Prefix(owl:=) Prefix(rdf:=) Prefix(xml:=) Prefix(xsd:=) Prefix(rdfs:=) Ontology( Annotation(rdfs:comment "This is an experimental ontology made for exploring the refactoring of GO molecular function based on the work of Paul Thomas. It should NOT be used in annotation.") Declaration(Class()) AnnotationAssertion(rdfs:label "high affinity zinc uptake transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.5.1.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Zn2+(out) = Zn2+(in), probably powered by proton motive force. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "low-affinity zinc ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Zn2+ = Zn2+, probably powered by proton motive force. In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "1,6-alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-1,6-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mcc"^^xsd:string) Annotation( "PMID:2644248"^^xsd:string) "Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->6) linkage."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "trans-hexaprenyltranstransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R05612"^^xsd:string) Annotation( "RHEA:20839"^^xsd:string) "Catalysis of the reaction: all-trans-hexaprenyl diphosphate + isopentenyl diphosphate = all-trans-heptaprenyl diphosphate + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "ssDNA-specific endodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(rdfs:label "single-stranded DNA endodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion( "single-stranded DNA specific endodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within a single-stranded deoxyribonucleic acid molecule by creating internal breaks."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.108"^^xsd:string) "lactase-phlorizin hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lactase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.108"^^xsd:string) "Catalysis of the reaction: lactose + H2O = D-glucose + D-galactose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.108"^^xsd:string) "lactose galactohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mcc"^^xsd:string) Annotation( "PMID:10521541"^^xsd:string) "Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-1,2-mannosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:cjm"^^xsd:string) "Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a mannosylphosphate group from one compound to another."^^xsd:string) AnnotationAssertion(rdfs:label "mannosylphosphate transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mcc"^^xsd:string) Annotation( "PMID:10521541"^^xsd:string) "Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->3) linkage."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-1,3-mannosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.2"^^xsd:string) "adenine aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.2"^^xsd:string) "ADase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.2"^^xsd:string) "Catalysis of the reaction: adenine + H2O = hypoxanthine + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.2"^^xsd:string) "adenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.2"^^xsd:string) "adenine aminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "adenine deaminase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acyl binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid."^^xsd:string) AnnotationAssertion( "acyl-CoA or acyl binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process"^^xsd:string) AnnotationAssertion( "acyl carrier activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:22221"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP) as part of the process of fatty acid biosynthesis."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.2.12"^^xsd:string) Annotation( "PMID:11433365"^^xsd:string) Annotation( "PMID:9242921"^^xsd:string) "Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2)."^^xsd:string) AnnotationAssertion(rdfs:label "peptidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.12"^^xsd:string) "peptidyl-tRNA:aminoacyl-tRNA N-peptidyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tRNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with transfer RNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group."^^xsd:string) AnnotationAssertion( "acyl-CoA or acyl binding"^^xsd:string) AnnotationAssertion(rdfs:label "fatty-acyl-CoA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "histidine/arginine/lysine/ornithine porter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-ornithine from one side of a membrane to the other. L-ornithine is 2,5-diaminopentanoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "L-ornithine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "L-ornithine transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "S-adenosyl methionine permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "S-adenosyl-L-methionine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "SAM transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "S-adenosyl methionine transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism."^^xsd:string) AnnotationAssertion( "S-adenosylmethionine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "S-adenosylmethionine transporter activity"^^xsd:string) AnnotationAssertion( "S-adenosylmethionine permease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of sulfur amino acids from one side of a membrane to the other. Sulphur amino acids contain sulfur in the form of cystine, methionine or their derivatives."^^xsd:string) AnnotationAssertion( "sulfur amino acid transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfur amino acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "sulphur amino acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "sulphur amino acid transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "S-methylmethionine transporter activity"^^xsd:string) AnnotationAssertion( "S-methylmethionine permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "S-methylmethionine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of S-methylmethionine from one side of a membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-methionine porter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of L-methionine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport."^^xsd:string) AnnotationAssertion(rdfs:label "L-methionine secondary active transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.99.1"^^xsd:string) "fumaric hydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "succinate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.1"^^xsd:string) "succinodehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.1"^^xsd:string) "succinic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.1"^^xsd:string) "succinic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.1"^^xsd:string) "succinyl dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.1"^^xsd:string) "succinate:(acceptor) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.1"^^xsd:string) Annotation( "GOC:kd"^^xsd:string) "Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.1"^^xsd:string) "succinate:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.1"^^xsd:string) "fumarate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.1"^^xsd:string) "succinate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.1"^^xsd:string) "fumarate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "imidazole glycerol phosphate synthase activity"^^xsd:string) AnnotationAssertion( "imidazoleglycerol phosphate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "imidazoleglycerol-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:GLUTAMIDOTRANS-RXN"^^xsd:string) "Catalysis of the reaction: phosphoribulosylformimino-AICAR-P + L-glutamine = D-erythro-imidazole-glycerol-phosphate + aminoimidazole carboxamide ribonucleotide + L-glutamate + 2 H(+)."^^xsd:string) AnnotationAssertion( "imidazole-glycerol-phosphate synthase activity"^^xsd:string) AnnotationAssertion( "glutamine amidotransferase:cyclase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.21"^^xsd:string) "glycerol-1-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.21"^^xsd:string) "glycerol 3-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.21"^^xsd:string) "Catalysis of the reaction: glycerol-1-phosphate + H2O = glycerol + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "glycerol-1-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.21"^^xsd:string) "glycerol-3-phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.21"^^xsd:string) "alpha-glycerol phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.21"^^xsd:string) "glycerol 3-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.21"^^xsd:string) "alpha-glycerophosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.101"^^xsd:string) "palmitoyl-dihydroxyacetone-phosphate reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acylglycerone-phosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.101"^^xsd:string) "palmitoyl dihydroxyacetone phosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.101"^^xsd:string) "palmitoyldihydroxyacetone-phosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.101"^^xsd:string) "acyldihydroxyacetone phosphate reductase activity"^^xsd:string) AnnotationAssertion( "1-acyldihydroxyacetone-phosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.101"^^xsd:string) "1-palmitoylglycerol-3-phosphate:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.101"^^xsd:string) "Catalysis of the reaction: 1-palmitoylglycerol-3-phosphate + NADP+ = palmitoylglycerone phosphate + NADPH + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0815316194"^^xsd:string) "Catalysis of movement along a microfilament, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP)."^^xsd:string) AnnotationAssertion( "actin-filament motor activity"^^xsd:string) AnnotationAssertion( "myosin ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "microfilament motor activity"^^xsd:string) AnnotationAssertion( "muscle motor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "actin filament motor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12642621"^^xsd:string) "Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein."^^xsd:string) AnnotationAssertion( "SNAP receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "SNARE binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) "Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA."^^xsd:string) AnnotationAssertion(rdfs:label "recombinase activity"^^xsd:string) AnnotationAssertion( "strand transferase"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "two-component sensor activity"^^xsd:string) AnnotationAssertion( "two-component system sensor activity "^^xsd:string) AnnotationAssertion(rdfs:label "phosphorelay sensor kinase activity"^^xsd:string) AnnotationAssertion( "two-component sensor molecule"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mcc"^^xsd:string) Annotation( "PMID:10966457"^^xsd:string) Annotation( "PMID:20223701"^^xsd:string) Annotation( "PMID:9191038"^^xsd:string) "Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:10966457"^^xsd:string) Annotation( "PMID:11842140"^^xsd:string) "Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response."^^xsd:string) AnnotationAssertion( "two-component response regulator activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphorelay response regulator activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nucleotide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:9556590"^^xsd:string) "Catalysis of the hydroxylation of sphingolipid long chain bases."^^xsd:string) AnnotationAssertion(rdfs:label "sphingosine hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ribonuclease MRP activity"^^xsd:string) AnnotationAssertion( "RNase MRP"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17881380"^^xsd:string) "Catalysis of the site-specific cleavage of RNA by a catalytic RNA-mediated mechanism; substrates include the A3 site in the ITS1 of pre-rRNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3'-5' exoribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "3'-5'-exoribonuclease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:02532"^^xsd:string) "S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:1555811337"^^xsd:string) Annotation( "PMID:10690410"^^xsd:string) "Catalysis of the dimethylation two adjacent A residues in the loop closing the 3'-terminal stem of the 18S rRNA, using S-adenosyl-L-methionine as a methyl donor."^^xsd:string) AnnotationAssertion(rdfs:label "rRNA (adenine-N6,N6-)-dimethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:02532"^^xsd:string) "dimethyladenosine transferase activity"^^xsd:string) AnnotationAssertion( "18S rRNA dimethylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "rDNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with DNA sequences encoding ribosomal RNA."^^xsd:string) AnnotationAssertion( "ribosomal DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "NAD diphosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "NAD+ diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.22"^^xsd:string) "NADH pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.22"^^xsd:string) "NAD+ pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.22"^^xsd:string) "NAD(+) pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.22"^^xsd:string) "nicotinamide adenine dinucleotide pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.22"^^xsd:string) "NADP pyrophosphatase activity"^^xsd:string) AnnotationAssertion( "NAD pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.22"^^xsd:string) "Catalysis of the reaction: NAD+ + H2O = AMP + NMN."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.22"^^xsd:string) "NAD+ phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.27.9"^^xsd:string) "splicing endonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.9"^^xsd:string) "tRNA-splicing endonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.9"^^xsd:string) "transfer splicing endonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.9"^^xsd:string) "tRNATRPintron endonuclease activity"^^xsd:string) AnnotationAssertion( "tRNA-intron endoribonuclease activity"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA-intron endonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.9"^^xsd:string) "Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.9"^^xsd:string) "transfer ribonucleate intron endoribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.9"^^xsd:string) "tRNA splicing endonuclease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.160"^^xsd:string) "2'-phospho-tRNA:NAD+ phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.160"^^xsd:string) "yeast 2'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.160"^^xsd:string) "Tpt1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.160"^^xsd:string) Annotation( "PMID:9148937"^^xsd:string) "Catalysis of the reaction: 2'-phospho-[ligated tRNA] + NAD+ = mature tRNA + ADP ribose 1'',2''-phosphate + nicotinamide + H2O. This reaction is the transfer of the splice junction 2-phosphate from ligated tRNA to NAD+ to produce ADP-ribose 1'-2' cyclic phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "tRNA 2'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.160"^^xsd:string) "2'-phospho-[ligated tRNA]:NAD+ phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.160"^^xsd:string) "Tpt1p"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA secondary structure binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with DNA containing secondary structure elements such as four-way junctions, bubbles, loops, Y-form DNA, or double-strand/single-strand junctions."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.52"^^xsd:string) "Catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.52"^^xsd:string) "N-linked-glycopeptide-(N-acetyl-beta-D-glucosaminyl)-L-asparagine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.52"^^xsd:string) "PNGase F"^^xsd:string) AnnotationAssertion(rdfs:label "peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.52"^^xsd:string) "N-glycanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.52"^^xsd:string) "N-oligosaccharide glycopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.52"^^xsd:string) "glycopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.52"^^xsd:string) "PNGase A"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.52"^^xsd:string) "glycopeptide N-glycosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.52"^^xsd:string) "jack-bean glycopeptidase"^^xsd:string) AnnotationAssertion( "PNGase"^^xsd:string) AnnotationAssertion( "peptide:N-glycanase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.89"^^xsd:string) "Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane."^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylglucosaminylphosphatidylinositol deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.89"^^xsd:string) "acetylglucosaminylphosphatidylinositol deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.89"^^xsd:string) "GlcNAc-PI de-N-acetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.89"^^xsd:string) "GlcNAc-PI deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.89"^^xsd:string) "6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.89"^^xsd:string) "N-acetyl-D-glucosaminylphosphatidylinositol acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.89"^^xsd:string) "N-acetylglucosaminylphosphatidylinositol de-N-acetylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxaloacetate secondary active transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of oxaloacetate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport."^^xsd:string) AnnotationAssertion( "oxaloacetate carrier activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.103"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + ethanolamine phosphate = S-adenosyl-L-homocysteine + N-methylethanolamine phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "phosphoethanolamine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.103"^^xsd:string) "phosphoethanolamine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.103"^^xsd:string) "S-adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.71"^^xsd:string) "sterol Delta(24(28))-methylene reductase activity"^^xsd:string) AnnotationAssertion( "sterol delta-24(28) methylene reductase activity"^^xsd:string) AnnotationAssertion( "D24(24-1)-sterol reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.71"^^xsd:string) "ergosterol:NADP+ delta24(241)-oxidoreductase activity"^^xsd:string) AnnotationAssertion( "sterol delta-24(28) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.71"^^xsd:string) "sterol delta24(28)-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.71"^^xsd:string) "sterol delta24(28)-methylene reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.71"^^xsd:string) "C-24(28) sterol reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.71"^^xsd:string) "delta24(241)-sterol reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "delta24(24-1) sterol reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.71"^^xsd:string) "sterol Delta(24(28))-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.71"^^xsd:string) Annotation( "RHEA:18504"^^xsd:string) "Catalysis of the reaction: ergosterol + NADP(+) = ergosta-5,7,22,24(24(1))-tetraen-3beta-ol + H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN3O-203"^^xsd:string) Annotation( "PMID:8988026"^^xsd:string) "Catalysis of the reaction which results in unsaturation at C-7 in the B ring of sterols."^^xsd:string) AnnotationAssertion(rdfs:label "C-8 sterol isomerase activity"^^xsd:string) AnnotationAssertion( "delta-8-delta-7 sterol isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "C-5 sterol desaturase activity"^^xsd:string) AnnotationAssertion( "sterol-C5-desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN3O-227"^^xsd:string) "Catalysis of the reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN3O-227"^^xsd:string) "Catalysis of the formation of the C-22(23) double bond in the sterol side chain. An example reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+."^^xsd:string) AnnotationAssertion(rdfs:label "C-22 sterol desaturase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.99.7"^^xsd:string) "(S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.7"^^xsd:string) "lanosterol 2,3-oxidosqualene cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.7"^^xsd:string) "oxidosqualene--lanosterol cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.7"^^xsd:string) "2,3-oxidosqualene sterol cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.7"^^xsd:string) "squalene epoxidase-cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.7"^^xsd:string) "2,3-epoxysqualene--lanosterol cyclase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lanosterol synthase activity"^^xsd:string) AnnotationAssertion( "OSC"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18033581"^^xsd:string) "oxidosqualene:lanosterol cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.7"^^xsd:string) "squalene 2,3-epoxide:lanosterol cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.7"^^xsd:string) "2,3-oxidosqualene-lanosterol cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.7"^^xsd:string) "2,3-epoxysqualene lanosterol cyclase activity"^^xsd:string) AnnotationAssertion( "2,3-epoxysqualene-lanosterol cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.7"^^xsd:string) "squalene-2,3-oxide-lanosterol cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.7"^^xsd:string) Annotation( "RHEA:14624"^^xsd:string) "Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus."^^xsd:string) AnnotationAssertion( "oxidosqualene-lanosterol cyclase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.170"^^xsd:string) Annotation( "PMID:9811880"^^xsd:string) "Catalysis of the reaction: 3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8,24-dien-4-alpha-carboxylate + NAD(P)+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + CO2 + NAD(P)H."^^xsd:string) AnnotationAssertion( "sterol-4-carboxylate 3-dehydrogenase (decarboxylating) activity"^^xsd:string) AnnotationAssertion( "3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate:NAD(P)+ 3-oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.170"^^xsd:string) "3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)"^^xsd:string) AnnotationAssertion( "sterol 4alpha-carboxylic decarboxylase activity"^^xsd:string) AnnotationAssertion( "3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)"^^xsd:string) AnnotationAssertion( "sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating)"^^xsd:string) AnnotationAssertion( "C-3 sterol dehydrogenase (C-4 decarboxylase) activity"^^xsd:string) AnnotationAssertion( "3beta-hydroxy-4beta-methylcholestenoate dehydrogenase activity"^^xsd:string) AnnotationAssertion( "C-3 sterol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.270"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "MetaCyc:1.1.1.270-RXN"^^xsd:string) Annotation( "MetaCyc:RXN3O-4110"^^xsd:string) Annotation( "MetaCyc:RXN66-19"^^xsd:string) Annotation( "MetaCyc:RXN66-24"^^xsd:string) Annotation( "MetaCyc:RXN66-314"^^xsd:string) Annotation( "MetaCyc:RXN66-319"^^xsd:string) Annotation( "PMID:9811880"^^xsd:string) "Catalysis of the reaction: a 3-beta-hydroxyl sterol + NADP+ = a 3-keto sterol + NADPH + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.270"^^xsd:string) "3beta-hydroxy-steroid:NADP+ 3-oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.270"^^xsd:string) "3-KSR activity"^^xsd:string) AnnotationAssertion( "3-keto-steroid reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-keto sterol reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "4-methylsterol oxidase activity"^^xsd:string) AnnotationAssertion( "methylsterol hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.72"^^xsd:string) "4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.72"^^xsd:string) "4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.72"^^xsd:string) Annotation( "PMID:9811880"^^xsd:string) "Catalysis of the reaction: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)H + H(+) + O2 = 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)+ + H2O."^^xsd:string) AnnotationAssertion( "methylsterol monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "C-4 methylsterol oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.5.1"^^xsd:string) Annotation( "GOC:kd"^^xsd:string) "Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH3. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.5.1"^^xsd:string) "benzonitrilase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nitrilase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.5.1"^^xsd:string) "nitrile aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.5.1"^^xsd:string) "acetonitrilase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peroxisome targeting sequence binding"^^xsd:string) AnnotationAssertion( "peroxisome targeting signal receptor"^^xsd:string) AnnotationAssertion( "PTS binding"^^xsd:string) AnnotationAssertion( "PTS receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0879693568"^^xsd:string) "Interacting selectively and non-covalently with a peroxisomal targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Enables the energy independent passage of toxins, sized less than 1000 Da, across a membrane towards the outside of the cell. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria."^^xsd:string) AnnotationAssertion(rdfs:label "toxin export channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.59"^^xsd:string) "cytochrome c-lysine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[cytochrome c]-lysine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.59"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + cytochrome c L-lysine = S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine. This is the addition of a methyl group to the N6 atom of a lysine residue in cytochrome c."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.59"^^xsd:string) "S-adenosyl-L-methionine:cytochrome c-L-lysine 6-N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.59"^^xsd:string) "S-adenosyl-L-methionine:cytochrome c-L-lysine N6-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.59"^^xsd:string) "cytochrome c (lysine) methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.59"^^xsd:string) "cytochrome c methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.59"^^xsd:string) "cytochrome c-specific protein-lysine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.59"^^xsd:string) "cytochrome c-specific protein methylase III activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.150"^^xsd:string) "type III PIP kinase activity"^^xsd:string) AnnotationAssertion( "phosphatidylinositol-3-phosphate 5-kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-phosphatidylinositol-3-phosphate 5-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.150"^^xsd:string) "ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.150"^^xsd:string) Annotation( "RHEA:13612"^^xsd:string) "Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.150"^^xsd:string) "phosphatidylinositol 3-phosphate 5-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.1.1"^^xsd:string) "alpha-alanine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.1"^^xsd:string) "L-alanine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.1"^^xsd:string) "NADH-dependent alanine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.1"^^xsd:string) "L-alanine:NAD+ oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.1"^^xsd:string) "Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.1"^^xsd:string) "AlaDH"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.1"^^xsd:string) "NAD-dependent alanine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.1"^^xsd:string) "alanine oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alanine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.1"^^xsd:string) "NAD-linked alanine dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with magnesium (Mg) ions."^^xsd:string) AnnotationAssertion(rdfs:label "magnesium ion binding"^^xsd:string) AnnotationAssertion( "magnesium binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.16.1.7"^^xsd:string) "iron chelate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.7"^^xsd:string) "NADH:Fe3+-EDTA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.7"^^xsd:string) "NADH:Fe(3+)-EDTA reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ferric-chelate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.7"^^xsd:string) "NADH:Fe(3+) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.7"^^xsd:string) "Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.7"^^xsd:string) "Fe(II):NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.7"^^xsd:string) "NADH2:Fe3+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.7"^^xsd:string) "ferric chelate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.7"^^xsd:string) "NADH:Fe3+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11566870"^^xsd:string) "Catalysis of the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "adenine nucleotide transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "spermine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of spermine from one side of the membrane to the other. Spermine is a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.10"^^xsd:string) "polyphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.10"^^xsd:string) "metaphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.10"^^xsd:string) "polyphosphate depolymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.10"^^xsd:string) "polyphosphate polyphosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "endopolyphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.10"^^xsd:string) "polymetaphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.10"^^xsd:string) "Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 phosphate residues."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.1"^^xsd:string) "NAD+ diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.1"^^xsd:string) "NMN adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.1"^^xsd:string) "NAD+ pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.1"^^xsd:string) "nicotinamide adenine dinucleotide pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.1"^^xsd:string) "Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.1"^^xsd:string) "NMNAT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.1"^^xsd:string) "adenosine triphosphate-nicotinamide mononucleotide transadenylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.1"^^xsd:string) "NAD(+) diphosphorylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nicotinamide-nucleotide adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.1"^^xsd:string) "nicotinamide mononucleotide adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.1"^^xsd:string) "ATP:NMN adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.1"^^xsd:string) "diphosphopyridine nucleotide pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.1"^^xsd:string) "NAD(+) pyrophosphorylase activity"^^xsd:string) AnnotationAssertion( "ATP:nicotinamide-nucleotide adenylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.22"^^xsd:string) "XMP:diphosphate 5-phospho-alpha-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.22"^^xsd:string) "Xan phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.22"^^xsd:string) Annotation( "GOC:clt"^^xsd:string) "Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + xanthine = (9-D-ribosylxanthine)-5'-phosphate + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.22"^^xsd:string) "5-phospho-alpha-D-ribose-1-diphosphate:xanthine phospho-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "xanthine phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion( "xanthine-guanine phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.22"^^xsd:string) "XMP pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.22"^^xsd:string) "xanthosine 5'-phosphate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.22"^^xsd:string) "xanthylate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.22"^^xsd:string) "xanthylic pyrophosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:as"^^xsd:string) "Catalysis of the transfer of sulfite ions from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "sulfite transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "sulphite transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "template for synthesis of G-rich strand of telomere DNA activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11812242"^^xsd:string) "Provision of the template used by reverse transcriptase to synthesize the G-rich strand of telomeric DNA."^^xsd:string) AnnotationAssertion( "telomerase, template"^^xsd:string) AnnotationAssertion( "telomerase RNA"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.6"^^xsd:string) "3HAO"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.6"^^xsd:string) "3-hydroxyanthranilic oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.6"^^xsd:string) "3-hydroxyanthranilate oxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxyanthranilate 3,4-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.6"^^xsd:string) Annotation( "RHEA:17956"^^xsd:string) "Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.6"^^xsd:string) "3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.6"^^xsd:string) "3-hydroxyanthranilic acid dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.6"^^xsd:string) "3-hydroxyanthranilic acid oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule."^^xsd:string) AnnotationAssertion( "binding to mRNA cap"^^xsd:string) AnnotationAssertion( "snRNA cap binding"^^xsd:string) AnnotationAssertion(rdfs:label "RNA cap binding"^^xsd:string) AnnotationAssertion( "mRNA cap binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "RNA m7G cap binding"^^xsd:string) AnnotationAssertion(rdfs:label "RNA 7-methylguanosine cap binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with the 7-methylguanosine group added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "RNA m2,2,7G cap binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with the trimethylguanosine (m(3)(2,2,7)-GTP) group located at the 5' end of some RNA molecules. Such trimethylated cap structures, generally produced by posttranscriptional modification of a 7-methylguanosine cap, are often found on snRNAs and snoRNAs transcribed by RNA polymerase II, but have also be found on snRNAs transcribed by RNA polymerase III. They have also been found on a subset of the mRNA population in some species, e.g. C. elegans."^^xsd:string) AnnotationAssertion(rdfs:label "RNA trimethylguanosine cap binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "PMID:10880518"^^xsd:string) Annotation( "PMID:12121975"^^xsd:string) "Interacting selectively and non-covalently with a hypermethylated cap structure consisting of 7-methylguanosine (m(7)G) followed by four methylated nucleotides (cap 4): 7-methylguanosine-ppp-N6, N6, 2'-O-trimethyladenosine-p-2'-O-methyladenosine-p-2'-O-methylcytosine-p-N3, 2'-O-dimethyluridine Such caps are known to be found at the 5' ends of SL RNAs of trypanosomatid protozoa."^^xsd:string) AnnotationAssertion(rdfs:label "RNA cap 4 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "lariat formation, 5'-splice site cleavage"^^xsd:string) AnnotationAssertion(rdfs:label "first spliceosomal transesterification activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "ISBN:0879695897"^^xsd:string) "Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the 3' exon."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3'-splice site cleavage, exon ligation"^^xsd:string) AnnotationAssertion(rdfs:label "second spliceosomal transesterification activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "ISBN:0879695897"^^xsd:string) "Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure."^^xsd:string) AnnotationAssertion( "lariat formation, 5'-splice site cleavage"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Holliday junction binding"^^xsd:string) AnnotationAssertion( "forked DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "ISBN:0815332181"^^xsd:string) Annotation( "PMID:15563464"^^xsd:string) "Interacting selectively and non-covalently with DNA containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices."^^xsd:string) AnnotationAssertion(rdfs:label "four-way junction DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "open form four-way junction DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "ISBN:0815332181"^^xsd:string) Annotation( "PMID:15563464"^^xsd:string) "Interacting selectively and non-covalently with DNA containing the open form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The open form of a four-way junction can be diagrammed without any of the strands crossing over."^^xsd:string) AnnotationAssertion( "open form Holliday junction binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "crossed form Holliday junction binding"^^xsd:string) AnnotationAssertion(rdfs:label "crossed form four-way junction DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "ISBN:0815332181"^^xsd:string) Annotation( "PMID:15563464"^^xsd:string) "Interacting selectively and non-covalently with DNA containing the crossed form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The crossed form of a four-way junction cannot be diagrammed without any of the strands crossing over, and instead contains a single crossover between two of the strands."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Y-form DNA binding"^^xsd:string) AnnotationAssertion( "splayed Y-form DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:16781730"^^xsd:string) "Interacting selectively and non-covalently with segment of DNA shaped like a Y. This shape occurs when DNA contains a region of paired double-stranded DNA on one end and a region of unpaired DNA strands on the opposite end."^^xsd:string) AnnotationAssertion( "forked DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "loop DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:16781730"^^xsd:string) "Interacting selectively and non-covalently with DNA containing a loop. A loop occurs when DNA contains a large insertion or deletion that causes a region of unpaired single-stranded DNA to loop out, while the rest of the DNA is in a paired double-stranded configuration."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:16781730"^^xsd:string) "Interacting selectively and non-covalently with DNA that contains a bubble. A bubble occurs when DNA contains a region of unpaired, single-stranded DNA flanked on both sides by regions of paired, double-stranded DNA."^^xsd:string) AnnotationAssertion(rdfs:label "bubble DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "double-strand/single-strand DNA junction binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:16781730"^^xsd:string) "Interacting selectively and non-covalently with a region of DNA that contains double-stranded DNA flanked by a region of single-stranded DNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "base pairing"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target nucleic acid molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target DNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "base pairing with DNA"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with ribonucleic acid (RNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target RNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "base pairing with RNA"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with messenger ribonucleic acid (mRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target mRNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "base pairing with mRNA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:9224623"^^xsd:string) "Catalysis of the removal of single bases present in mismatches by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site."^^xsd:string) AnnotationAssertion(rdfs:label "mismatch base pair DNA N-glycosylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "purine-specific mismatch base pair DNA N-glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:9224623"^^xsd:string) "Catalysis of the removal of purines present in mismatches, especially opposite oxidized purines, by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site."^^xsd:string) AnnotationAssertion( "A/G-specific adenine DNA glycosylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidized base lesion DNA N-glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:11554296"^^xsd:string) "Catalysis of the removal of oxidized bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "endonuclease VIII activity"^^xsd:string) AnnotationAssertion( "DNA glycosylase/AP-lyase"^^xsd:string) AnnotationAssertion( "endonuclease III"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "oxidized pyrimidine base lesion DNA N-glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:11554296"^^xsd:string) "Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site."^^xsd:string) AnnotationAssertion( "pyrimidine-specific oxidized base lesion DNA N-glycosylase activity"^^xsd:string) AnnotationAssertion( "DNA glycosylase/beta-lyase"^^xsd:string) AnnotationAssertion( "endodeoxyribonuclease III"^^xsd:string) AnnotationAssertion(rdfs:label "oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity"^^xsd:string) AnnotationAssertion( "bifunctional DNA glycosylase"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:9224623"^^xsd:string) "Catalysis of the removal of pyrimidine dimers by removing the 5' pyrimidine of the dimer by cleaving the N-C1' glycosidic bond between the 5' pyrimidine of the dimer and the deoxyribose sugar. The reaction releases the 5' pyrimidine of the dimer and leaves an apurinic (AP) site. The reaction involves the formation of a covalent enzyme substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site."^^xsd:string) AnnotationAssertion(rdfs:label "pyrimidine dimer DNA N-glycosylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.4"^^xsd:string) "aminopropanol oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.4"^^xsd:string) "D-1-amino-2-propanol:NAD(2) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.4"^^xsd:string) "(R)-2,3-butanediol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.4"^^xsd:string) "diacetyl (acetoin) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.4"^^xsd:string) "2,3-butanediol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.4"^^xsd:string) "butylene glycol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.4"^^xsd:string) "D-1-amino-2-propanol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.4"^^xsd:string) "D-aminopropanol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.4"^^xsd:string) "(R)-diacetyl reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(R,R)-butanediol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.4"^^xsd:string) "Catalysis of the reversible reaction: (R,R)-butane-2,3-diol + NAD+ = (R)-acetoin + NADH + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.4"^^xsd:string) "D-(-)-butanediol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.4"^^xsd:string) "D-butanediol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.4"^^xsd:string) "1-amino-2-propanol oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.4"^^xsd:string) "butyleneglycol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.4"^^xsd:string) "1-amino-2-propanol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mating pheromone activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:clt"^^xsd:string) Annotation( "GOC:elh"^^xsd:string) "The activity of binding to and activating specific cell surface receptors, thereby inducing a behavioral or physiological response(s) from a responding organism or cell that leads to the transfer or union of genetic material between organisms or cells. The mating pheromone can either be retained on the cell surface or secreted."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.71"^^xsd:string) "phosphatidylethanolamine methyltransferase I"^^xsd:string) AnnotationAssertion( "PLMT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.71"^^xsd:string) "methyltransferase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.71"^^xsd:string) "phosphatidylmonomethylethanolamine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.71"^^xsd:string) "phospholipid methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.71"^^xsd:string) "S-adenosyl-L-methionine:phosphatidyl-N-methylethanolamine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.71"^^xsd:string) "phosphatidyl-N-monomethylethanolamine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.71"^^xsd:string) "phosphatidyl-N-methylethanolamine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.71"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidyl-N-methylethanolamine N-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "adenyl-nucleotide exchange factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kd"^^xsd:string) "Stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.81"^^xsd:string) Annotation( "GOC:kad"^^xsd:string) Annotation( "MetaCyc:RXN-11277"^^xsd:string) Annotation( "PMID:8567632"^^xsd:string) Annotation( "PMID:9452443"^^xsd:string) "Catalysis of the reaction: a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycerol 3-phosphate + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "diacylglycerol diphosphate phosphatase activity"^^xsd:string) AnnotationAssertion( "diacylglycerol pyrophosphate phosphatase activity"^^xsd:string) AnnotationAssertion( "DGPP phosphohydrolase activity"^^xsd:string) AnnotationAssertion( "DGPP phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with inositol hexakisphosphate."^^xsd:string) AnnotationAssertion( "IP6 binding"^^xsd:string) AnnotationAssertion( "InsP6 binding"^^xsd:string) AnnotationAssertion(rdfs:label "inositol hexakisphosphate binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:2.7.1.151-RXN"^^xsd:string) "Catalysis of the reaction: D-myo-inositol 1,4,5-trisphosphate + ATP = D-myo-inositol 1,4,5,6-tetrakisphosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "inositol-1,4,5-trisphosphate 6-kinase activity"^^xsd:string) AnnotationAssertion( "inositol trisphosphate 6-kinase activity"^^xsd:string) AnnotationAssertion( "inositol polyphosphate multikinase activity"^^xsd:string) AnnotationAssertion( "ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion( "IpmK"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "inositol 1,4,5,6-tetrakisphosphate 3-kinase activity"^^xsd:string) AnnotationAssertion( "IpmK"^^xsd:string) AnnotationAssertion( "inositol polyphosphate multikinase activity"^^xsd:string) AnnotationAssertion( "1D-myo-inositol-tetrakisphosphate 3-kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol tetrakisphosphate 3-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) "Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate."^^xsd:string) AnnotationAssertion( "EC:2.7.1.151"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) "Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP."^^xsd:string) AnnotationAssertion( "1D-myo-inositol-tetrakisphosphate 6-kinase activity"^^xsd:string) AnnotationAssertion( "inositol 1,3,4,5-tetrakisphosphate 6-kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol tetrakisphosphate 6-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol-1,3,4,5,6-pentakisphosphate kinase activity"^^xsd:string) AnnotationAssertion( "EC:2.7.4.21"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:11311242"^^xsd:string) "Catalysis of the reaction: ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol tetrakisphosphate is unknown."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:16429326"^^xsd:string) "Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown."^^xsd:string) AnnotationAssertion(rdfs:label "inositol hexakisphosphate kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol heptakisphosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:16429326"^^xsd:string) "Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate. The isomeric configurations of the diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) and bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4) are unknown."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol hexakisphosphate 4-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:16429326"^^xsd:string) "Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:16429326"^^xsd:string) "Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "inositol hexakisphosphate 6-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:2.7.1.152-RXN"^^xsd:string) "Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate."^^xsd:string) AnnotationAssertion( "ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol hexakisphosphate 5-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "diphosphoinositol-pentakisphosphate 4-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:16429326"^^xsd:string) "Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "inositol heptakisphosphate 4-kinase activity"^^xsd:string) AnnotationAssertion( "IP7 4-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol heptakisphosphate 6-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:16429326"^^xsd:string) "Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:clt"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid."^^xsd:string) AnnotationAssertion(rdfs:label "translation repressor activity, nucleic acid binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "translation repressor activity, non-nucleic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:clt"^^xsd:string) "Antagonizes the ribosome-mediated translation of mRNA into a polypeptide but does not bind directly to nucleic acid."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:LUMAZINESYN-CPLX"^^xsd:string) "lumazine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.-.-"^^xsd:string) Annotation( "PMID:7559556"^^xsd:string) "Catalysis of the reaction: 3,4-dihydroxy-2-butanone-4-phosphate + 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione = 6,7-dimethyl-8-ribityllumazine + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "6,7-dimethyl-8-ribityllumazine synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sulphonate dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfonate dioxygenase activity"^^xsd:string) AnnotationAssertion( "sulfonate/alpha-ketoglutarate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.-"^^xsd:string) Annotation( "GOC:clt"^^xsd:string) Annotation( "PMID:10482536"^^xsd:string) "Catalysis of the reaction: sulfonate + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.17"^^xsd:string) "taurine, 2-oxoglutarate:O2 oxidoreductase (sulfite-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "taurine dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.17"^^xsd:string) Annotation( "RHEA:15912"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + O(2) + taurine = aminoacetaldehyde + CO(2) + succinate + sulfite."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.17"^^xsd:string) "2-aminoethanesulfonate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.17"^^xsd:string) "alpha-ketoglutarate-dependent taurine dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "base pairing with rRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with ribosomal ribonucleic acid (rRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target rRNA molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "base pairing with snRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with small nuclear ribonucleic acid (snRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target snRNA molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "base pairing with tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with transfer ribonucleic acid (mRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target tRNA molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a DNA region that regulates a DNA-based process. Such processes include transcription, DNA replication, and DNA repair."^^xsd:string) AnnotationAssertion(rdfs:label "regulatory region DNA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon."^^xsd:string) AnnotationAssertion(rdfs:label "transcription regulatory region sequence-specific DNA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II regulatory region sequence-specific DNA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II."^^xsd:string) AnnotationAssertion( "RNA polymerase II upstream activating sequence (UAS) sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II core promoter proximal region sequence-specific DNA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase II basal transcription machinery."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II core promoter sequence-specific DNA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase II distal enhancer sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sequence-specific DNA binding RNA polymerase II transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to modulate transcription by RNAP II."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence in an RNA polymerase II (Pol II) core promoter, the region composed of the transcription start site and binding sites for transcription factors of the Pol II basal transcription machinery, in order to modulate transcription by Pol II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "bacterial-type RNA polymerase regulatory region sequence-specific DNA binding"^^xsd:string) AnnotationAssertion( "eubacterial-type RNA polymerase regulatory region sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is part of a regulatory region that controls the transcription of a gene or operon by a bacterial-type RNA polymerase."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "eubacterial-type RNA polymerase core promoter sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence in a bacterial-type RNA polymerase core promoter, the region composed of the transcription start site and binding sites for transcription factors of the basal transcription machinery, in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex."^^xsd:string) AnnotationAssertion(rdfs:label "bacterial-type RNA polymerase core promoter sequence-specific DNA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "eubacterial-type RNA polymerase regulatory transcription factor sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for a bacterial-type RNA polymerase."^^xsd:string) AnnotationAssertion(rdfs:label "bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "core promoter proximal region sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to the core promoter. The transcribed region might be described as a gene, cistron, or operon."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "transcription factor binding transcription regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well."^^xsd:string) AnnotationAssertion(rdfs:label "core RNA polymerase binding transcription regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well."^^xsd:string) AnnotationAssertion(rdfs:label "core RNA polymerase II binding transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "polymerase III regulatory region sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is part of a regulatory region that controls transcription by RNA polymerase III. The transcribed region might be contain a single gene or a cistron containing multiple genes."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase II core binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with RNA polymerase III core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase III core binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well."^^xsd:string) AnnotationAssertion(rdfs:label "core RNA polymerase III binding transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a DNA-dependent core RNA polymerase to form a holoenzyme complex and also, while present in the holoenzyme, interacting with promoter sequences in order to confer sequence specific recognition of promoter DNA sequence motifs."^^xsd:string) AnnotationAssertion(rdfs:label "core DNA-dependent RNA polymerase binding promoter specificity activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "mitochondrial RNA polymerase core promoter sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is part of the core promoter for the mitochondrial RNA polymerase."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bacterial-type RNA polymerase core enzyme binding"^^xsd:string) AnnotationAssertion( "eubacterial-type RNA polymerase core enzyme binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with the bacterial-type RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one omega subunit."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mitochondrial single-subunit type RNA polymerase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:20701995"^^xsd:string) Annotation( "PMID:2088182"^^xsd:string) "Interacting selectively and non-covalently with a single subunit mitochondrial RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase III type 1 promoter sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is a part of a type 1 promoter that controls transcription by RNA polymerase III. Type 1 promoters are found in 5S rRNA genes, downstream of the transcription start site within the sequence of the mature RNA, and require TFIIIA for recognition."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is a part of a type 2 promoter that controls transcription by RNA polymerase III. Type 2 promoters consist of an A box and a B box downstream of the transcription start site within the sequence within the sequence of the mature RNA. Type 2 promoters are found in many tRNA genes as well as in other small RNAs."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase III type 2 promoter sequence-specific DNA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase III promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "The function of binding to a specific DNA sequence motif in an RNA polymerase III (Pol III) promoter in order to recruit the Pol III recruiting factor TFIIIB to the promoter."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "TFIIIC-type activity"^^xsd:string) AnnotationAssertion( "TFIIIA activity"^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase III type 1 promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "The function of binding to a specific DNA sequence motif in a type 1 RNA polymerase III (Pol III) promoter in order to recruit the Pol III recruiting factor TFIIIB to the promoter. For type 1 Pol III promoters, this requires both TFIIIA and TFIIIC."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is a part of a type 3 promoter that controls transcription by RNA polymerase III (Pol III). A type 3 Pol III promoter is composed of elements upstream of the transcription start site, including a TATA box. The human U6 snRNA gene has a type 3 promoter. Type 3 Pol III promoters have not been observed in S. cerevisiae."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase III type 3 promoter sequence-specific DNA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase III transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase III transcription factor binding transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "type 2 RNA polymerase III promoter recognition"^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase III type 2 promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence motif in a type 2 RNA polymerase III (Pol III) promoter in order to recruit TFIIIB to the promoter. For type 2 Pol III promoters, this requires TFIIIC activity."^^xsd:string) AnnotationAssertion( "TFIIIC-type activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "sequence-specific DNA binding transcription factor recruiting transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "The function of binding to a specific DNA sequence and recruiting another transcription factor to the DNA in order to modulate transcription. The recruited factor may bind DNA directly, or may be colocalized via protein-protein interactions."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence and recruiting RNA polymerase to the DNA in order to form the preinitiation complex (PIC)."^^xsd:string) AnnotationAssertion(rdfs:label "sequence-specific DNA binding RNA polymerase recruiting transcription factor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase II regulatory region DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with a DNA region that controls the transcription of a region of DNA by RNA polymerase II. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with a DNA region that controls the transcription of a region of DNA by RNA polymerase I. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase I regulatory region DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase III regulatory region DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with a DNA region that controls the transcription of a gene by RNA polymerase III. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a DNA region that controls the transcription of a gene or operon by a bacterial-type RNA polymerase. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors."^^xsd:string) AnnotationAssertion( "eubacterial-type RNA polymerase regulatory region DNA binding"^^xsd:string) AnnotationAssertion(rdfs:label "bacterial-type RNA polymerase regulatory region DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mitochondrial RNA polymerase regulatory region DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:20056105"^^xsd:string) "Interacting selectively and non-covalently with a DNA region that controls the transcription of a region of DNA by mitochondrial RNA polymerase. Binding may occur as a high affinity and sequence specific interaction or as a lower affinity interaction observed once a factor has been recruited to the DNA by other factors."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "plastid RNA polymerase regulatory region DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with a DNA region that controls the transcription of a region of DNA by a plastid RNA polymerase. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase III transcription factor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase III transcription factor, any protein required to initiate or regulate transcription by RNA polymerase III."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, Once recruited to an RNA polymerase III promoter by one or more other transcription factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex."^^xsd:string) AnnotationAssertion(rdfs:label "TFIIIB-type transcription factor activity"^^xsd:string) AnnotationAssertion( "RNA polymerase III recruiting transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 1 promoter by TFIIIA-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase III type 1 promoter TFIIIB-type transcription factor activity"^^xsd:string) AnnotationAssertion( "RNA polymerase III type 1 promoter polymerase recruiting transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase III type 2 promoter TFIIIB-type transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 2 promoter by a TFIIIC-type factor, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex."^^xsd:string) AnnotationAssertion( "RNA polymerase III type 2 promoter polymerase recruiting transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 3 promoter by SNAP-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase III type 3 promoter TFIIIB-type transcription factor activity"^^xsd:string) AnnotationAssertion( "RNA polymerase III type 3 promoter polymerase recruiting transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase III type 1 promoter DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with a region of DNA that is a part of a type 1 promoter that controls transcription by RNA polymerase III. Type 1 promoters are found in 5S rRNA genes, downstream of the transcription start site within the sequence of the mature RNA, and require TFIIIA for recognition."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase III type 2 promoter DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with a region of DNA that is a part of a type 2 promoter that controls transcription by RNA polymerase III. Type 2 promoters consist of an A box and a B box downstream of the transcription start site within the sequence within the sequence of the mature RNA. Type 2 promoters are found in many tRNA genes as well as in other small RNAs."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with a region of DNA that is a part of a type 3 promoter that controls transcription by RNA polymerase III. A type 3 Pol III promoter is composed of elements upstream of the transcription start site, including a TATA box. The human U6 snRNA gene has a type 3 promoter. Type 3 Pol III promoters have not been observed in S. cerevisiae."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase III type 3 promoter DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase III type 3 promoter TFIIIB recruiting transcription factor activity"^^xsd:string) AnnotationAssertion( "type 3 RNA polymerase III promoter recognition"^^xsd:string) AnnotationAssertion( "SNAPc-type activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "The function of binding to a specific DNA sequence motif in a type 3 RNA polymerase III (Pol III) promoter in order to recruit TFIIIB to the promoter. For type 3 Pol III promoters, this requires SNAPc activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "sequence-specific DNA binding RNA polymerase III transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase III. The transcription factor may or may not also interact selectively with a protein or macromolecular complex."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with a region of DNA that is a part of a hybrid promoter that controls transcription by RNA polymerase III (Pol III). A hybrid Pol III promoter contains both regulatory elements both upstream and downstream of the transcription initiation site. An example gene with such a promoter is the S. cerevisiae U6 gene."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase III hybrid type promoter DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Once recruited to an RNA polymerase III hybrid type promoter by sequence-specific DNA binding transcription factors, direct DNA binding, or a combination of both, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase III hybrid type promoter TFIIIB recruiting transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase III hybrid type promoter sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is a part of a hybrid type promoter that controls transcription by RNA polymerase III (Pol III). A hybrid Pol III promoter contains both regulatory elements both upstream and downstream of the transcription initiation site. An example gene with such a promoter is the S. cerevisiae U6 gene."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III hybrid type promoter, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase III hybrid type promoter TFIIIB-type transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase I core binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with RNA polymerase I core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a specific sequence of DNA that controls the transcription of a region of DNA by mitochondrial RNA polymerase."^^xsd:string) AnnotationAssertion(rdfs:label "mitochondrial RNA polymerase regulatory region sequence-specific DNA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mitochondrial RNA polymerase core promoter proximal region sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:20670382"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for a mitochondrial RNA polymerase."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "core promoter sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is part of a core promoter region composed of the transcription start site and binding sites for the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors."^^xsd:string) AnnotationAssertion(rdfs:label "core promoter binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase IV core binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:19110459"^^xsd:string) "Interacting selectively and non-covalently with RNA polymerase IV core enzyme, a multisubunit eukaryotic nuclear RNA polymerase found in plants and involved in siRNA production."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase V core binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:19110459"^^xsd:string) "Interacting selectively and non-covalently with RNA polymerase V core enzyme, a multisubunit eukaryotic nuclear RNA polymerase found in plants and involved in production of noncoding transcripts at target loci for silencing."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "SP6-type RNA polymerase binding"^^xsd:string) AnnotationAssertion( "T3/T7 type RNA polymerase binding"^^xsd:string) AnnotationAssertion( "T3-type RNA polymerase binding"^^xsd:string) AnnotationAssertion(rdfs:label "single-subunit type RNA polymerase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:20701995"^^xsd:string) "Interacting selectively and non-covalently with a single subunit RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6."^^xsd:string) AnnotationAssertion( "T7-type RNA polymerase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "plastid single-subunit type RNA polymerase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:20701995"^^xsd:string) "Interacting selectively and non-covalently with a single subunit plastid RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "plastid PEP RNA polymerase core enzyme binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:20701995"^^xsd:string) "Interacting selectively and non-covalently with the bacterial-type plastid PEP RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one double prime subunit."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "plastid sigma factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:20701995"^^xsd:string) "Interacting selectively and non-covalently with a plastid PEP core RNA polymerase to form a holoenzyme complex and also, while present in the holoenzyme, interacting with promoter sequences in order to confer sequence specific recognition of plastid PEP core promoter DNA sequence motifs."^^xsd:string) AnnotationAssertion( "sigma transcription factor"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "DNA-directed RNA polymerase activity involved in transcription from RNA polymerase I promoter"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase I specific promoter to direct initiation and catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase I activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase II activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'."^^xsd:string) AnnotationAssertion( "DNA-directed RNA polymerase activity involved in transcription from RNA polymerase II promoter"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase III activity"^^xsd:string) AnnotationAssertion( "DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase III specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase IV specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase IV activity"^^xsd:string) AnnotationAssertion( "DNA-directed RNA polymerase activity involved in transcription from RNA polymerase IV promoter"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "DNA-directed RNA polymerase activity involved in transcription from RNA polymerase V promoter"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase V specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase V activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bacterial-type RNA polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a bacterial-type specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:20701995"^^xsd:string) "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a plastid PEP-A RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'."^^xsd:string) AnnotationAssertion(rdfs:label "plastid PEP-A RNA polymerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:20701995"^^xsd:string) "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a plastid PEP-B RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'."^^xsd:string) AnnotationAssertion(rdfs:label "plastid PEP-B RNA polymerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "single subunit type RNA polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single subunit type RNA polymerase specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'."^^xsd:string) AnnotationAssertion( "T3/T7 type RNA polymerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single subunit type mitochondrial RNA polymerase specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'."^^xsd:string) AnnotationAssertion(rdfs:label "mitochondrial single subunit type RNA polymerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:20701995"^^xsd:string) "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single subunit type plastid RNA polymerase specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'."^^xsd:string) AnnotationAssertion(rdfs:label "plastid single subunit type RNA polymerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a nucleic acid region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair."^^xsd:string) AnnotationAssertion(rdfs:label "regulatory region nucleic acid binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a RNA region within the transcript that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon."^^xsd:string) AnnotationAssertion(rdfs:label "transcription regulatory region RNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "regulatory region RNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a RNA region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA binding transcription antitermination factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:8332211"^^xsd:string) "Binds to RNA, typically within the nascent RNA transcript, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind the nascent RNA include the lambda N protein and the HIV-1 tat protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA binding transcription antitermination factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:8332211"^^xsd:string) "Binds to DNA, typically within region of the promoter and transcribed region, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind DNA include the lambda Q protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to promote assembly of the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase II promoter."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence in an RNA polymerase II (Pol II) core promoter, the region composed of the transcription start site and binding sites for transcription factors of the Pol II basal transcription machinery, in order to promote assembly of the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase II promoter."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly"^^xsd:string) AnnotationAssertion( "sequence-specific core promoter binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase II transcription factor binding transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase I transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase I transcription factor binding transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II basal transcription factor binding transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "TFIID-class binding transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIID class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II transcription factor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIA class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well."^^xsd:string) AnnotationAssertion(rdfs:label "TFIIA-class binding transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIB class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well."^^xsd:string) AnnotationAssertion(rdfs:label "TFIIB-class binding transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "TFIIE-class binding transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIE class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "TFIIF-class binding transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIF class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "TFIIH-class binding transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIH class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, any of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II basal transcription factor binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "TFIIA-class transcription factor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIA class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "TFIIB-class transcription factor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIB class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "TFIID-class transcription factor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIID class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "TFIIE-class transcription factor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIE class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "TFIIF-class transcription factor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIF class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "TFIIH-class transcription factor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIH class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "basal transcription machinery binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with the basal transcription machinery which is composed of the RNA polymerase core enzyme and the basal transcription factor(s), the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "basal RNA polymerase II transcription machinery binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with the basal transcription machinery for RNA polymerase II which is composed of the RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits, and the basal RNA polymerase II transcription factors, the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase II activating transcription factor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase II repressing transcription factor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase II transcription repressing factor, a protein involved in negative regulation of transcription."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "RNA polymerase II transcriptional co-regulator"^^xsd:string) AnnotationAssertion( "thyroid receptor-associated protein"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:10213677"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the basal RNAP II transcription machinery."^^xsd:string) AnnotationAssertion( "TRAP protein"^^xsd:string) AnnotationAssertion( "RNA polymerase II transcription mediator activity"^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II transcription cofactor activity"^^xsd:string) AnnotationAssertion( "RNA polymerase II transcriptional cofactor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:10213677"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between activating transcription factors and the basal RNAP II transcription machinery."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II transcription coactivator activity"^^xsd:string) AnnotationAssertion( "RNA polymerase II transcription co-activator activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "RNA polymerase II transcription co-repressor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:10213677"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase II repressing transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II transcription corepressor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "basal bacterial-type RNA polymerase transcription machinery binding"^^xsd:string) AnnotationAssertion(rdfs:label "bacterial-type RNA polymerase holo enzyme binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with the basal transcription machinery which is composed of a bacterial-type RNA polymerase core enzyme and a sigma factor, the minimal set of factors required for formation of the preinitiation complex (PIC) by a bacterial-type RNA polymerase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to increase the frequency, rate or stability of the aggregation, arrangement and bonding together of proteins on RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC). Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between activating transcription factors and the basal RNAP II transcription machinery."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs), to facilitate the aggregation, arrangement and bonding together of proteins on RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase."^^xsd:string) AnnotationAssertion(rdfs:label "TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly"^^xsd:string) AnnotationAssertion( "TATA-binding protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for a bacterial-type RNA polymerase in order to modulate transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex."^^xsd:string) AnnotationAssertion(rdfs:label "bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "TATA-binding protein binding RNA polymerase II transcription factor activity"^^xsd:string) AnnotationAssertion( "TRF protein binding RNA polymerase II transcription factor activity"^^xsd:string) AnnotationAssertion(rdfs:label "TBP-class protein binding RNA polymerase II transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs), in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA by RNA polymerase II and recruiting another transcription factor to the DNA in order to modulate transcription by RNAP II."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, recruiting that specific transcription factor to the transcription machinery complex and thus permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well."^^xsd:string) AnnotationAssertion(rdfs:label "transcription factor recruiting transcription factor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase II transcription factor recruiting transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "The function of binding to an RNA polymerase II (RNAP II) transcription factor and recruiting it to the transcription machinery complex in order to modulate transcription by RNAP II."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "TFIIE-class transcription factor recruiting transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with a basal RNA polymerase II (RNAP II) transcription factor of the TFIIE-class in order to recruit it to the RNAP II preinitiation complex (PIC) in order to modulate transcription by RNAP II."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "TFIIF-class transcription factor recruiting transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with a basal RNA polymerase II (RNAP II) transcription factor of the TFIIF-class in order to recruit it to the RNAP II preinitiation complex (PIC) in order to modulate transcription by RNAP II."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "TFIIH-class transcription factor recruiting transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with a basal RNA polymerase II (RNAP II) transcription factor of the TFIIH-class in order to recruit it to the RNAP II preinitiation complex (PIC) in order to modulate transcription by RNAP II."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "core RNA polymerase II recruiting transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:20491932"^^xsd:string) Annotation( "PMID:20629756"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for a bacterial-type RNA polymerase in order to modulate transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex."^^xsd:string) AnnotationAssertion(rdfs:label "bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:20491932"^^xsd:string) Annotation( "PMID:20629756"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for a bacterial-type RNA polymerase in order to stop, prevent, or reduce the frequency, rate or extent of transcription from a bacterial-type RNA polymerase promoter."^^xsd:string) AnnotationAssertion(rdfs:label "bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sequence-specific DNA binding mitochondrial RNA polymerase transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:18391175"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by mitochondrial RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:18391175"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence that is part of the core promoter for mitochondrial RNA polymerase in order to modulate transcription by mitochondrial RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex."^^xsd:string) AnnotationAssertion(rdfs:label "mitochondrial RNA polymerase core promoter sequence-specific DNA binding transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:18391175"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for a mitochondrial RNA polymerase in order to modulate transcription by mitochondrial RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex."^^xsd:string) AnnotationAssertion(rdfs:label "mitochondrial RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "mitochondrial RNA polymerase termination site sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:18391175"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is a terminator for mitochondrial RNA polymerase."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mitochondrial RNA polymerase terminator site sequence-specific DNA binding transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:18391175"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is a terminator for mitochondrial RNA polymerase in order to promote transcription termination by mitochondrial RNA polymerase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "transcription termination site sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:18280161"^^xsd:string) Annotation( "PMID:18391175"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that promotes termination by RNA polymerase. The transcribed region might be described as a gene, cistron, or operon."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bacterial-type RNA polymerase termination site sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:18280161"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is a terminator for bacterial-type RNA polymerase."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bacterial-type RNA polymerase termination site sequence-specific DNA binding transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:18280161"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is a termination site for bacterial-type RNA polymerase in order to promote transcription termination by bacterial-type RNA polymerase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:11282468"^^xsd:string) Annotation( "PMID:20629756"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is an enhancer region that helps activate transcription of a gene or operon by a bacterial-type RNA polymerase. Enhancers for sigma-54 holoenzymes are typically located 80 to 150 base pairs upstream from the transcription start site, although they can be further away or may be downstream of the promoter. Some transcription units dependent on sigma-70 holoenzymes may also include enhancer sequences."^^xsd:string) AnnotationAssertion(rdfs:label "bacterial-type RNA polymerase enhancer sequence-specific DNA binding"^^xsd:string) AnnotationAssertion( "bacterial-type RNA polymerase upstream activating sequence (UAS) sequence-specific DNA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bacterial-type RNA polymerase transcription enhancer sequence-specific DNA binding transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:20629756"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is a bacterial-type enhancer region in order to activate transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. Enhancers for sigma-54 holoenzymes are typically located 80 to 150 base pairs upstream from the transcription start site. Some transcription units dependent on sigma-70 holoenzymes may also include enhancer sequences."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase III type 1 promoter sequence-specific DNA binding TFIIIC recruiting transcription factor activity"^^xsd:string) AnnotationAssertion( "type 1 RNA polymerase III promoter recognition"^^xsd:string) AnnotationAssertion( "TFIIIA activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "The function of binding to a specific DNA sequence motif in a type 1 RNA polymerase III (Pol III) promoter in order to recruit the transcription factor TFIIIC to the promoter."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase III transcription factor recruiting transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "The function of binding to an RNA polymerase III (RNAP III) transcription factor and recruiting it to the transcription machinery complex in order to modulate transcription by RNAP III."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase III transcription factor of the TFIIIB class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III."^^xsd:string) AnnotationAssertion(rdfs:label "TFIIIB-class transcription factor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase III transcription factor of the TFIIIA class, one of the factors involved in formation of the preinitiation complex (PIC) at type 1 promoters (5S genes) by RNA polymerase III."^^xsd:string) AnnotationAssertion(rdfs:label "TFIIIA-class transcription factor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "TFIIIC-class transcription factor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase III transcription factor of the TFIIIC class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) "The function of binding to a specific DNA sequence motif in a type 1 RNA polymerase III (Pol III) promoter in order to recruit the Pol III recruiting factor TFIIIB to the promoter. For type 1 Pol III promoters, this requires both TFIIIA and TFIIIC."^^xsd:string) AnnotationAssertion( "TFIIIC-type activity"^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase III type 1 promoter TFIIIB recruiting transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a specific sequence of DNA that is part of an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter."^^xsd:string) AnnotationAssertion(rdfs:label "enhancer sequence-specific DNA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a region of DNA that is in cis with and relatively close to the core promoter. The transcribed region might be described as a gene, cistron, or operon."^^xsd:string) AnnotationAssertion(rdfs:label "core promoter proximal region DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "transcription termination site DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a region of DNA that promotes termination by RNA polymerase. The transcribed region might be described as a gene, cistron, or operon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an intronic DNA sequence that regulates the transcription of the transcript it is contained within."^^xsd:string) AnnotationAssertion(rdfs:label "intronic transcription regulatory region sequence-specific DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase II intronic DNA sequence that regulates the transcription of the transcript it is contained within."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase I."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase I regulatory region sequence-specific DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase I CORE element sequence-specific DNA binding"^^xsd:string) AnnotationAssertion( "RNA polymerase I core promoter sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12865296"^^xsd:string) Annotation( "PMID:14969726"^^xsd:string) Annotation( "PMID:8057832"^^xsd:string) "Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery. This site is often referred to as the CORE element. In mammalian cells, the CORE element functions in conjunction with the Upstream Control Element (UCE), while in fungi, protozoa, and plants, the CORE element functions without a UCE."^^xsd:string) AnnotationAssertion( "RNA polymerase I core element sequence-specific DNA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12865296"^^xsd:string) Annotation( "PMID:14969726"^^xsd:string) Annotation( "PMID:8057832"^^xsd:string) "Interacting selectively and non-covalently with the upstream control element (UCE, or alternately referred to as the upstream element), a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase I."^^xsd:string) AnnotationAssertion( "RNA polymerase I upstream element sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase I upstream control element sequence-specific DNA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase I enhancer sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12865296"^^xsd:string) Annotation( "PMID:14969726"^^xsd:string) Annotation( "PMID:8057832"^^xsd:string) "Interacting selectively and non-covalently with a RNA polymerase I (Pol I) enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sequence-specific DNA binding RNA polymerase I transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase I. The transcription factor may or may not also interact selectively with a protein or macromolecular complex."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12865296"^^xsd:string) Annotation( "PMID:14969726"^^xsd:string) Annotation( "PMID:8057832"^^xsd:string) "Interacting selectively and non-covalently with the upstream control element (UCE, or alternately referred to as the upstream element, UE), a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase I in order to modulate transcription by RNA polymerase I."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase I upstream control element sequence-specific DNA binding transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase I CORE element sequence-specific DNA binding transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12865296"^^xsd:string) Annotation( "PMID:14969726"^^xsd:string) Annotation( "PMID:8057832"^^xsd:string) "Interacting selectively and non-covalently with CORE element, a regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery in order to modulate transcription by RNA polymerase I."^^xsd:string) AnnotationAssertion( "RNA polymerase I core promoter sequence-specific DNA binding transcription factor"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase I enhancer sequence-specific DNA binding transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12865296"^^xsd:string) Annotation( "PMID:14969726"^^xsd:string) Annotation( "PMID:8057832"^^xsd:string) "Interacting selectively and non-covalently with a RNA polymerase I (Pol I) enhancer in order to modulate transcription by RNA polymerase I."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase I transcription factor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase I transcription factor, any protein required to initiate or regulate transcription by RNA polymerase I."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase I (RNAP I) complex, typically composed of fourteen subunits, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well."^^xsd:string) AnnotationAssertion(rdfs:label "core RNA polymerase I binding transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) Annotation( "PMID:14969726"^^xsd:string) Annotation( "PMID:8057832"^^xsd:string) "The function of binding to an RNA polymerase I (RNAP I) transcription factor and recruiting it to the transcription machinery complex in order to modulate transcription by RNAP I."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase I transcription factor recruiting transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12381659"^^xsd:string) Annotation( "PMID:14969726"^^xsd:string) Annotation( "PMID:8057832"^^xsd:string) "Interacting selectively and non-covalently with the CORE element, a regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery and also binding to an RNA polymerase I (RNAP I) transcription factor to recruit it to the transcription machinery complex in order to modulate transcription by RNA polymerase I."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to increase the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:9811836"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12829264"^^xsd:string) Annotation( "PMID:12829265"^^xsd:string) Annotation( "PMID:22084422"^^xsd:string) Annotation( "PMID:2674688"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence and interacting selectively and non-covalently with any metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of those metal ions, in such a way that metal ion binding regulates the activity of the transcription factor in order to modulate transcription by an RNA polymerase. Specific mechanisms include increasing or decreasing the ability of the transcription factor to interact selectively and non-covalently with a specific DNA sequence (for example S. cerevisiae Cup2p or the prokaryotic SmtB/ArsR family, changing the conformation of transcription factor bound DNA between the apo- and metal-bound forms of the transcription factor. Additional mechanisms may exist."^^xsd:string) AnnotationAssertion(rdfs:label "metal ion regulated sequence-specific DNA binding transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12829264"^^xsd:string) Annotation( "PMID:12829265"^^xsd:string) Annotation( "PMID:2674688"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence and interacting selectively and non-covalently with any metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of those metal ions, in such a way that metal ion binding regulates the activity of the transcription factor in order to modulate transcription by RNA polymerase II. Specific mechanisms include increasing or decreasing the ability of the transcription factor to interact selectively and non-covalently with a specific DNA sequence (for example S. cerevisiae Cup2p or the prokaryotic SmtB/ArsR family, changing the conformation of transcription factor bound DNA between the apo- and metal-bound forms of the transcription factor. Additional mechanisms may exist."^^xsd:string) AnnotationAssertion(rdfs:label "metal ion regulated sequence-specific DNA binding RNA polymerase II transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12829264"^^xsd:string) Annotation( "PMID:12829265"^^xsd:string) Annotation( "PMID:22084422"^^xsd:string) Annotation( "PMID:2674688"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) and interacting selectively and non-covalently with any metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of those metal ions, in such a way that metal ion binding regulates the activity of the transcription factor that binds the core promoter proximal region in order to modulate transcription by RNA polymerase II. Specific mechanisms include increasing or decreasing the ability of the transcription factor to interact selectively and non-covalently with a specific DNA sequence (for example S. cerevisiae Cup2p or the prokaryotic SmtB/ArsR family, changing the conformation of transcription factor bound DNA between the apo- and metal-bound forms of the transcription factor. Additional mechanisms may exist."^^xsd:string) AnnotationAssertion(rdfs:label "metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:22084422"^^xsd:string) Annotation( "PMID:2674688"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) and interacting selectively and non-covalently with copper(I) (Cu+) ion(s) and responding, e.g. by conformational change, to changes in the cellular level of copper(I) (Cu+), such a way that copper ion binding regulates the activity of the transcription factor, perhaps by regulating the ability to interact selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II), or by regulating some other function of the transcription factor, in order to modulate transcription by RNAP II."^^xsd:string) AnnotationAssertion(rdfs:label "copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:22084422"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) and interacting selectively and non-covalently with zinc (Zn) ion(s) and responding, e.g. by conformational change, to changes in the cellular level of zinc (Zn), in such a way that zinc ion binding regulates the activity of the transcription factor, perhaps by regulating the ability to interact selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II), or by regulating some other function of the transcription factor, in order to modulate transcription by RNAP II."^^xsd:string) AnnotationAssertion(rdfs:label "zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12829264"^^xsd:string) Annotation( "PMID:12829265"^^xsd:string) Annotation( "PMID:22084422"^^xsd:string) Annotation( "PMID:2674688"^^xsd:string) "Interacting selectively and non-covalently with a specific bacterial-type transcription regulatory DNA sequence and interacting selectively and non-covalently with any metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of those metal ions, in such a way that metal ion binding regulates the activity of the transcription factor in order to modulate transcription by a bacterial-type RNA polymerase. Specific mechanisms include increasing or decreasing the ability of the transcription factor to interact selectively and non-covalently with a specific DNA sequence (for example S. cerevisiae Cup2p or the prokaryotic SmtB/ArsR family, changing the conformation of transcription factor bound DNA between the apo- and metal-bound forms of the transcription factor. Additional mechanisms may exist."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in positive regulation of transcription"^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in negative regulation of transcription"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12829264"^^xsd:string) Annotation( "PMID:12829265"^^xsd:string) Annotation( "PMID:22084422"^^xsd:string) Annotation( "PMID:2674688"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence and interacting selectively and non-covalently with any metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of those metal ions, in such a way that metal ion binding regulates the activity of the transcription factor in order to activate or increase the frequency, rate or extent of cellular DNA-dependent transcription by an RNA polymerase. Specific mechanisms include increasing or decreasing the ability of the transcription factor to interact selectively and non-covalently with a specific DNA sequence (for example S. cerevisiae Cup2p or the prokaryotic SmtB/ArsR family, changing the conformation of transcription factor bound DNA between the apo- and metal-bound forms of the transcription factor. Additional mechanisms may exist."^^xsd:string) AnnotationAssertion(rdfs:label "metal ion regulated sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "metal ion regulated sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12829264"^^xsd:string) Annotation( "PMID:12829265"^^xsd:string) Annotation( "PMID:22084422"^^xsd:string) Annotation( "PMID:2674688"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence and interacting selectively and non-covalently with any metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of those metal ions, in such a way that metal ion binding regulates the activity of the transcription factor in order to stop, prevent, or reduce the frequency, rate or extent of cellular DNA-dependent transcription by an RNA polymerase. Specific mechanisms include increasing or decreasing the ability of the transcription factor to interact selectively and non-covalently with a specific DNA sequence (for example S. cerevisiae Cup2p or the prokaryotic SmtB/ArsR family, changing the conformation of transcription factor bound DNA between the apo- and metal-bound forms of the transcription factor. Additional mechanisms may exist."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:2674688"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) and interacting selectively and non-covalently with copper(I) (Cu+) ion(s) and responding, e.g. by conformational change, to changes in the cellular level of copper(I) (Cu+), such a way that copper ion binding regulates the activity of the transcription factor in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter."^^xsd:string) AnnotationAssertion(rdfs:label "copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) and interacting selectively and non-covalently with zinc (Zn) ion(s) and responding, e.g. by conformational change, to changes in the cellular level of zinc (Zn), such a way that copper ion binding regulates the activity of the transcription factor in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter."^^xsd:string) AnnotationAssertion(rdfs:label "zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:22084422"^^xsd:string) Annotation( "PMID:2674688"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) and interacting selectively and non-covalently with metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of metal ion, such a way that metal ion binding regulates the activity of the transcription factor in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter."^^xsd:string) AnnotationAssertion(rdfs:label "metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in negative regulation of transcription"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:22084422"^^xsd:string) Annotation( "PMID:2674688"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) and interacting selectively and non-covalently with metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of metal ion, such a way that metal ion binding regulates the activity of the transcription factor in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12829264"^^xsd:string) Annotation( "PMID:12829265"^^xsd:string) Annotation( "PMID:2674688"^^xsd:string) "Interacting selectively and non-covalently with a specific bacterial-type transcription regulatory DNA sequence and interacting selectively and non-covalently with any metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of those metal ions, in such a way that metal ion binding regulates the activity of the transcription factor in order to activate or increase the frequency, rate or extent of cellular DNA-dependent transcription by a bacterial-type RNA polymerase. Specific mechanisms include increasing or decreasing the ability of the transcription factor to interact selectively and non-covalently with a specific DNA sequence (for example S. cerevisiae Cup2p or the prokaryotic SmtB/ArsR family, changing the conformation of transcription factor bound DNA between the apo- and metal-bound forms of the transcription factor. Additional mechanisms may exist."^^xsd:string) AnnotationAssertion(rdfs:label "metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in positive regulation of transcription"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex."^^xsd:string) AnnotationAssertion(rdfs:label "sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in positive regulation of transcription"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:12829264"^^xsd:string) Annotation( "PMID:12829265"^^xsd:string) Annotation( "PMID:2674688"^^xsd:string) "Interacting selectively and non-covalently with a specific bacterial-type transcription regulatory DNA sequence and interacting selectively and non-covalently with any metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of those metal ions, in such a way that metal ion binding regulates the activity of the transcription factor in order to stop, prevent, or reduce the frequency, rate or extent of cellular DNA-dependent transcription by a bacterial-type RNA polymerase. Specific mechanisms include increasing or decreasing the ability of the transcription factor to interact selectively and non-covalently with a specific DNA sequence (for example S. cerevisiae Cup2p or the prokaryotic SmtB/ArsR family, changing the conformation of transcription factor bound DNA between the apo- and metal-bound forms of the transcription factor. Additional mechanisms may exist."^^xsd:string) AnnotationAssertion(rdfs:label "metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "copper ion sensor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "PMID:12829264"^^xsd:string) Annotation( "PMID:12829265"^^xsd:string) Annotation( "PMID:19928961"^^xsd:string) "Interacting selectively and non-covalently with a specific bacterial-type transcription regulatory DNA sequence and interacting selectively and non-covalently with copper(I) (Cu+) ion(s) and responding, e.g. by conformational change, to changes in the cellular level of copper(I) (Cu+), in such a way that copper ion binding regulates the activity of the transcription factor in order to stop, prevent, or reduce the frequency, rate or extent of cellular DNA-dependent transcription by a bacterial-type RNA polymerase."^^xsd:string) AnnotationAssertion(rdfs:label "copper ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "cadmium ion sensor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "PMID:12829264"^^xsd:string) Annotation( "PMID:12829265"^^xsd:string) Annotation( "PMID:19456862"^^xsd:string) "Interacting selectively and non-covalently with a specific bacterial-type transcription regulatory DNA sequence and interacting selectively and non-covalently with cadmium (Cd) ion(s) and responding, e.g. by conformational change, to changes in the cellular level of cadmium (Cd), in such a way that cadmium (Cd) ion binding regulates the activity of the transcription factor in order to stop, prevent, or reduce the frequency, rate or extent of cellular DNA-dependent transcription by a bacterial-type RNA polymerase."^^xsd:string) AnnotationAssertion(rdfs:label "cadmium ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with a transcription cofactor, any protein involved in regulation of transcription via protein-protein interactions with transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery."^^xsd:string) AnnotationAssertion(rdfs:label "transcription cofactor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with a transcription corepressor, any protein involved in negative regulation of transcription via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery."^^xsd:string) AnnotationAssertion(rdfs:label "transcription corepressor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with a transcription coactivator, any protein involved in positive regulation of transcription via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery."^^xsd:string) AnnotationAssertion(rdfs:label "transcription coactivator binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase II transcription cofactor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with a transcription cofactor for RNA polymerase II, any protein involved in regulation of transcription via protein-protein interactions with RNA polymerase II transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery of RNA polymerase II."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase II transcription coactivator binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase II transcription coactivator, any protein involved in positive regulation of transcription of RNA polymerase II via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery of RNA polymerase II."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase II transcription corepressor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase II transcription corepressor, any protein involved in negative regulation of transcription by RNA polymerase II via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery of RNA polymerase II."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in the regulatory region for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in the transcription regulatory region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mcc"^^xsd:string) Annotation( "PMID:12912892"^^xsd:string) "Catalysis of the transfer of glycerophosphodiesters from one side of a membrane to the other. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol."^^xsd:string) AnnotationAssertion(rdfs:label "glycerophosphodiester transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mcc"^^xsd:string) "Catalysis of the transfer of guanine nucleotides (GMP, GDP, and GTP) from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "guanine nucleotide transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.10.99.2"^^xsd:string) "Catalysis of the reaction: 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-ribofuranosyl)nicotinamide + a hydroquinone."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.99.2"^^xsd:string) "NQO2"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.99.2"^^xsd:string) "QR2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.99.2"^^xsd:string) "NRH:quinone oxidoreductase 2 activity"^^xsd:string) AnnotationAssertion( "ribosyldihydronicotinamide dehydrogenase (quinone) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.99.2"^^xsd:string) "NAD(P)H:quinone oxidoreductase-2"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.99.2"^^xsd:string) "quinone reductase 2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.99.2"^^xsd:string) "NAD(P)H:quinone oxidoreductase 2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.99.2"^^xsd:string) "NQO(2) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.99.2"^^xsd:string) "1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide:quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.99.2"^^xsd:string) "NAD(P)H:quinone oxidoreductase2"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.99.2"^^xsd:string) "N-ribosyldihydronicotinamide dehydrogenase (quinone) activity"^^xsd:string) AnnotationAssertion(rdfs:label "dihydronicotinamide riboside quinone reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Naturally occurring peptide that is an opioid (any non-alkaloid having an opiate-like effect that can be reversed by naloxone or other recognized morphine antagonist). These include Leu- and Met-enkephalin, dynorphin and neoendorphin, alpha, beta, gamma and delta endorphins formed from beta-lipotropin, various pronase-resistant peptides such as beta casamorphin, and other peptides whose opiate-like action seems to be indirect."^^xsd:string) AnnotationAssertion(rdfs:label "opioid peptide activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-acetylglucosamine 6-O-sulfotransferase activity"^^xsd:string) AnnotationAssertion( "N-acetylglucosamine 6-O-sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:hjd"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-glucosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-glucosamine 6-sulfate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "LPS binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11079463"^^xsd:string) "Interacting selectively and non-covalently with lipopolysaccharide."^^xsd:string) AnnotationAssertion(rdfs:label "lipopolysaccharide binding"^^xsd:string) AnnotationAssertion( "endotoxin binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-21"^^xsd:string) AnnotationAssertion( "interleukin-21 receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-21 receptor."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-21 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-21 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-21 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "IL-21R"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-21 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "N-acetylgalactosamine 4-O-sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.-"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-galactosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4-sulfate."^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylgalactosamine 4-O-sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-amyloid binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with beta-amyloid peptide/protein and/or its precursor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:10506570"^^xsd:string) "Combining with a phorbol ester and transmitting the signal to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "phorbol ester receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10506570"^^xsd:string) "Combining with a phorbol ester and transmitting the signal by a mechanism independent of kinase activity."^^xsd:string) AnnotationAssertion(rdfs:label "non-kinase phorbol ester receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.38"^^xsd:string) "cholesterol 25-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.38"^^xsd:string) Annotation( "RHEA:21107"^^xsd:string) "Catalysis of the reaction: AH(2) + cholesterol + O(2) = 25-hydroxycholesterol + A + H(2)O."^^xsd:string) AnnotationAssertion(rdfs:label "cholesterol 25-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.38"^^xsd:string) "cholesterol,hydrogen-donor:oxygen oxidoreductase (25-hydroxylating) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "non-tyrosine kinase FGFR activity"^^xsd:string) AnnotationAssertion( "non-tyrosine kinase FGF receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:11418238"^^xsd:string) "Combining with fibroblast growth factor (FGF) and transmitting the signal from one side of the membrane to the other by a mechanism independent of tyrosine kinase activity."^^xsd:string) AnnotationAssertion(rdfs:label "non-tyrosine kinase fibroblast growth factor receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:18571247"^^xsd:string) "Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "serotonin receptor activity, coupled via Gi/o"^^xsd:string) AnnotationAssertion(rdfs:label "Gi/o-coupled serotonin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "5-HT1 receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:18571247"^^xsd:string) Annotation( "PMID:18703043"^^xsd:string) "Combining with serotonin and transmitting the signal across the membrane by activation of the Gq/11 subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gq/11 subunit subsequently activates phospholipase C and results in an increase in inositol triphosphate (IP3) levels."^^xsd:string) AnnotationAssertion(rdfs:label "Gq/11-coupled serotonin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "5-HT2 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "serotonin receptor activity, coupled via Gq/11"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "dopamine D5 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0953351033"^^xsd:string) Annotation( "IUPHAR_RECEPTOR:2252"^^xsd:string) Annotation( "IUPHAR_RECEPTOR:2260"^^xsd:string) "Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gs to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "dopamine D1 receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "dopamine neurotransmitter receptor activity, coupled via Gs"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "dopamine D3 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0953351033"^^xsd:string) Annotation( "IUPHAR_RECEPTOR:2254"^^xsd:string) Annotation( "IUPHAR_RECEPTOR:2256"^^xsd:string) Annotation( "IUPHAR_RECEPTOR:2258"^^xsd:string) "Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gi/Go to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "dopamine D4 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "dopamine D2 receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "dopamine neurotransmitter receptor activity, coupled via Gi/Go"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19325074"^^xsd:string) "Combining with a trace amine to initiate a change in cell activity. Trace amines are biogenic amines that are synthesized from aromatic amino acids and are substrates for monoamine oxidase, and are therefore detectable only at trace levels in mammals."^^xsd:string) AnnotationAssertion(rdfs:label "trace-amine receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Combining with angiotensin to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "angiotensin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:10977869"^^xsd:string) "An angiotensin receptor activity that acts via Gq-mediated activation of phospholipase C followed by phosphoinositide hydrolysis and Ca2+ signaling, and may act via additional signaling mechanisms."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "PLC-activating angiotensin receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "angiotensin type I receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peptide YY receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9315606"^^xsd:string) "Combining with gut peptide YY to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pancreatic polypeptide receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9315606"^^xsd:string) "Combining with pancreatic polypeptide PP to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "urotensin II receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:15102493"^^xsd:string) "Combining with urotensin II to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "G10D receptor"^^xsd:string) AnnotationAssertion(rdfs:label "adrenomedullin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Combining with adrenomedullin to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "neuromedin U receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Combining with neuromedin U to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "NMUR activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "G protein coupled nucleotide receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled nucleotide receptor activity"^^xsd:string) AnnotationAssertion( "G-protein-coupled nucleotide receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "nucleotide receptor activity, G-protein coupled"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) Annotation( "IUPHAR_GPCR:1294"^^xsd:string) "Combining with a nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."^^xsd:string) AnnotationAssertion( "nucleotide receptor activity, G protein coupled"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:9755289"^^xsd:string) "P1 receptor"^^xsd:string) AnnotationAssertion( "G-protein-coupled adenosine receptor activity"^^xsd:string) AnnotationAssertion( "adenosine receptor activity, G protein coupled"^^xsd:string) AnnotationAssertion( "adenosine nucleotide receptor"^^xsd:string) AnnotationAssertion( "G protein coupled A1 adenosine receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "adenosine receptor activity, G-protein coupled"^^xsd:string) AnnotationAssertion( "A2A adenosine receptor activity, G-protein coupled"^^xsd:string) AnnotationAssertion( "G-protein-coupled A2A adenosine receptor activity"^^xsd:string) AnnotationAssertion( "A1 adenosine receptor activity, G-protein coupled"^^xsd:string) AnnotationAssertion( "G-protein-coupled A3 adenosine receptor activity"^^xsd:string) AnnotationAssertion( "A2B adenosine receptor activity, G protein coupled"^^xsd:string) AnnotationAssertion( "G-protein-coupled A1 adenosine receptor activity"^^xsd:string) AnnotationAssertion( "G protein coupled adenosine receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled adenosine receptor activity"^^xsd:string) AnnotationAssertion( "A1 adenosine receptor activity, G protein coupled"^^xsd:string) AnnotationAssertion( "G-protein-coupled A2B adenosine receptor activity"^^xsd:string) AnnotationAssertion( "A3 adenosine receptor activity, G protein coupled"^^xsd:string) AnnotationAssertion( "A2A adenosine receptor activity, G protein coupled"^^xsd:string) AnnotationAssertion( "G protein coupled A2B adenosine receptor activity"^^xsd:string) AnnotationAssertion( "A2B adenosine receptor activity, G-protein coupled"^^xsd:string) AnnotationAssertion( "A3 adenosine receptor activity, G-protein coupled"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9755289"^^xsd:string) "Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."^^xsd:string) AnnotationAssertion( "G protein coupled A2A adenosine receptor activity"^^xsd:string) AnnotationAssertion( "G protein coupled A3 adenosine receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:9755289"^^xsd:string) "P2 receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with a purine nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "purinergic nucleotide receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:17983853"^^xsd:string) "ghrelin receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "growth hormone secretagogue receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:17983853"^^xsd:string) "Combining with ghrelin to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) Annotation( "PMID:7621403"^^xsd:string) Annotation( "UniProtKB-KW:KW-1183"^^xsd:string) "Combining with a virus component and mediating entry of the virus into the cell."^^xsd:string) AnnotationAssertion(rdfs:label "virus receptor activity"^^xsd:string) AnnotationAssertion( "viral receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "platelet ADP receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:11196645"^^xsd:string) "Combining with ADP and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "ADP receptor activity"^^xsd:string) AnnotationAssertion( "K101 receptor"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "orphanin-FQ receptor activity"^^xsd:string) AnnotationAssertion( "ORPH receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "nociceptin/orphanin-FQ receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "nociceptin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PR:000012940"^^xsd:string) "OFQ receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:18670432"^^xsd:string) "Combining with the peptide nociceptin, and transmitting the signal across the membrane by activating an associated G-protein."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "X-opioid receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Combining with a cysteinyl leukotriene to initiate a change in cell activity. Cysteinyl leukotrienes are leukotrienes that contain a peptide group based on cysteine."^^xsd:string) AnnotationAssertion(rdfs:label "cysteinyl leukotriene receptor activity"^^xsd:string) AnnotationAssertion( "CysLT receptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "leukotriene B4 receptor activity"^^xsd:string) AnnotationAssertion( "BLT receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Combining with leukotriene B4, LTB4, to initiate a change in cell activity. Leukotriene B4 is also known as (6Z, 8E, 10E, 14Z)-(5S, 12R)-5,12-dihydroxyicosa-6,8,10,14-tetraen-1-oate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "pituitary adenylate cyclase-activating peptide receptor activity"^^xsd:string) AnnotationAssertion( "pituitary adenylate cyclase-activating polypeptide receptor activity"^^xsd:string) AnnotationAssertion( "pituitary adenylate cyclase activating polypeptide receptor"^^xsd:string) AnnotationAssertion( "PACAP receptor"^^xsd:string) AnnotationAssertion(rdfs:label "pituitary adenylate cyclase-activating polypeptide receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "A G-protein coupled receptor that interacts with pituitary adenylate cyclase-activating polypeptide."^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "pituitary adenylate cyclase activating protein receptor activity"^^xsd:string) AnnotationAssertion( "pituitary adenylyl cyclase activating protein receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcitonin gene-related polypeptide receptor activity"^^xsd:string) AnnotationAssertion( "CGRP receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12037140"^^xsd:string) "Combining with a calcitonin gene-related polypeptide to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "G-protein coupled chemoattractant receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."^^xsd:string) AnnotationAssertion( "G protein chemoattractant receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "G-protein chemoattractant receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "PLC activating metabotropic glutamate receptor activity"^^xsd:string) AnnotationAssertion( "group I metabotropic glutamate receptor activity"^^xsd:string) AnnotationAssertion( "Group I metabotropic glutamate receptor"^^xsd:string) AnnotationAssertion( "phospholipase C activating metabotropic glutamate receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "PLC activating G-protein coupled glutamate receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9016303"^^xsd:string) "A G-protein coupled receptor that binds glutamate and is linked to the inositol 1,4,5-trisphosphate/calcium signaling system."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "adenylate cyclase inhibiting metabotropic glutamate receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "adenylate cyclase inhibiting G-protein coupled glutamate receptor activity"^^xsd:string) AnnotationAssertion( "adenylyl cyclase inhibiting metabotropic glutamate receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) "Combining with glutamate and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex to inhibit downstream adenylate cyclase activity."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "group II metabotropic glutamate receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "A G-protein coupled receptor that is activated by trans-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) and inhibits adenylate cyclase activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:9016303"^^xsd:string) "A G-protein coupled receptor that is activated by L-AP-4 and inhibits adenylate cyclase activity."^^xsd:string) AnnotationAssertion(rdfs:label "group III metabotropic glutamate receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3',5'-cAMP receptor activity"^^xsd:string) AnnotationAssertion( "class E G-protein coupled receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pg"^^xsd:string) "Combining with cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "adenosine 3',5'-cyclophosphate receptor activity"^^xsd:string) AnnotationAssertion( "class E GPCR"^^xsd:string) AnnotationAssertion(rdfs:label "cAMP receptor activity"^^xsd:string) AnnotationAssertion( "3',5' cAMP receptor activity"^^xsd:string) AnnotationAssertion( "class E G protein coupled receptor"^^xsd:string) AnnotationAssertion( "cyclic AMP receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) "Combining with cytokinin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled cytokinin receptor activity"^^xsd:string) AnnotationAssertion( "G-protein-coupled cytokinin receptor activity"^^xsd:string) AnnotationAssertion( "G protein coupled cytokinin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "cytokinin receptor activity, G-protein coupled"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "proteinase activated receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:11356985"^^xsd:string) "A G-protein coupled peptide receptor activity that is initiated by cleavage of the N terminus of the receptor by a serine protease, resulting in the generation of a new tethered ligand that interacts with the receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peptide receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Combining with an extracellular or intracellular peptide to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "exogenous peptide receptor activity"^^xsd:string) AnnotationAssertion( "endogenous peptide receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "G-protein-coupled receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) "Interacting selectively and non-covalently with a G-protein coupled receptor."^^xsd:string) AnnotationAssertion( "G protein coupled receptor ligand"^^xsd:string) AnnotationAssertion( "G-protein-coupled receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled receptor binding"^^xsd:string) AnnotationAssertion( "G protein coupled receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.99.3"^^xsd:string) "GalNAc alpha-2,6-sialyltransferase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.3"^^xsd:string) "Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-[(2->6)-alpha-N-acetylneuraminyl]-(N-acetyl-D-galactosaminyl)-glycoprotein."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.3"^^xsd:string) "CMP-N-acetylneuraminate:glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein alpha-2,6-N-acetylneuraminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ATPase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ajp"^^xsd:string) "Functions to increase the rate of ATP hydrolysis."^^xsd:string) AnnotationAssertion( "ATPase stimulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "sialate 9(4)-O-acetylesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.53"^^xsd:string) Annotation( "PMID:1991039"^^xsd:string) "Catalysis of the reaction: N-acetyl-O-acetylneuraminate (free or glycosidically bound) + H2O = N-acetylneuraminate + acetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.53"^^xsd:string) "N-acetylneuraminate acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sialate O-acetylesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.53"^^xsd:string) "N-acyl-O-acetylneuraminate O-acetylhydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ajp"^^xsd:string) "Maintains the phosphorylation state of certain molecules by associating with them and preventing them from associating with active phosphatases, and thus inhibiting the enzyme activity without interacting with the enzyme. Often pertains to proteins belonging to dual-specificity phosphatase family but lacking critical active site residues."^^xsd:string) AnnotationAssertion(rdfs:label "pseudophosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-amino-acid oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.2"^^xsd:string) "L-amino-acid:oxygen oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.2"^^xsd:string) "Catalysis of the reaction: a L-amino acid + H2O + O2 = a 2-oxo acid + NH3 + hydrogen peroxide."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.2"^^xsd:string) "ophio-amino-acid oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Catalysis of the phosphorylation of a simple or complex lipid."^^xsd:string) AnnotationAssertion(rdfs:label "lipid kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.138"^^xsd:string) "ATP:ceramide 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.138"^^xsd:string) "acylsphingosine kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ceramide kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.138"^^xsd:string) "Catalysis of the reaction: ATP + ceramide = ADP + ceramide-1-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the reaction: ATP = pppA(2'p5'A)n oligomers. This reaction requires the binding of double-stranded RNA."^^xsd:string) AnnotationAssertion( "(2-5')oligo(A) synthetase activity"^^xsd:string) AnnotationAssertion( "oligo-2',5'-adenylate synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2'-5'-oligoadenylate synthetase activity"^^xsd:string) AnnotationAssertion( "2-5A synthetase activity"^^xsd:string) AnnotationAssertion( "2'-5' oligoadenylate synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "galactosylceramide sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.11"^^xsd:string) "galactocerebroside sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.11"^^xsd:string) "galactolipid sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.11"^^xsd:string) "GSase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.11"^^xsd:string) "glycosphingolipid sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.11"^^xsd:string) "3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.11"^^xsd:string) Annotation( "PMID:10727929"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate."^^xsd:string) AnnotationAssertion( "galactosylceramide sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.11"^^xsd:string) "3'-phosphoadenylyl-sulfate:galactosylceramide 3'-sulfotransferase activity"^^xsd:string) AnnotationAssertion( "cerebroside sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.11"^^xsd:string) "glycolipid sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + RRACH = S-adenosyl-L-homocysteine + RRm6ACH; R is a purine, and H is C, A, or U."^^xsd:string) AnnotationAssertion(rdfs:label "mRNA (N6-adenosine)-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "prenylcysteine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.3.5"^^xsd:string) "S-prenyl-L-cysteine:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.3.5"^^xsd:string) "prenylcysteine lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Catalysis of the reaction: S-prenyl-L-cysteine + O2 + H2O = a prenal + L-cysteine + H2O2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.36"^^xsd:string) "Catalysis of the reaction: retinal + NAD+ + H2O = retinoate + NADH. Acts on both 11-trans and 13-cis forms of retinal."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.36"^^xsd:string) "retinal:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.36"^^xsd:string) "cytosolic retinal dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "retinal dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.45"^^xsd:string) "alpha-amino-beta-carboxymuconate-epsilon-semialdehade decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.45"^^xsd:string) "alpha-amino-beta-carboxymuconate-epsilon-semialdehyde beta-decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.45"^^xsd:string) "picolinic acid decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.45"^^xsd:string) "2-amino-3-(3-oxoprop-2-enyl)but-2-enedioate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aminocarboxymuconate-semialdehyde decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.45"^^xsd:string) "2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.45"^^xsd:string) "picolinic acid carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.45"^^xsd:string) Annotation( "RHEA:16560"^^xsd:string) "Catalysis of the reaction: 2-amino-3-carboxymuconate 6-semialdehyde + H(+) = 2-aminomuconate 6-semialdehyde + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.45"^^xsd:string) "2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase (2-aminomuconate-semialdehyde-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Catalysis of the transfer of beta-alanine from one side of a membrane to the other. Beta-alanine is 3-aminopropanoic acid."^^xsd:string) AnnotationAssertion( "beta-alanine transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-alanine transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:14636584"^^xsd:string) "Interacting selectively and non-covalently with a phosphorylated tyrosine residue within a protein."^^xsd:string) AnnotationAssertion(rdfs:label "phosphotyrosine binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "prostaglandin J receptor activity"^^xsd:string) AnnotationAssertion( "PGJ(2) receptor activity"^^xsd:string) AnnotationAssertion( "PGJ receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12878180"^^xsd:string) "Combining with prostaglandin J (PGJ(2)), a metabolite of prostaglandin D (PGD(2)) to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "PMID:12000961"^^xsd:string) "Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylserine binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Interacting selectively and non-covalently with a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes."^^xsd:string) AnnotationAssertion(rdfs:label "polymeric immunoglobulin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "IgM binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Interacting selectively and non-covalently with an immunoglobulin of the IgM isotype."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "polymeric immunoglobulin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "IgM receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with an immunoglobulin of the IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Interacting selectively and non-covalently with an opsonin, such as a complement component or antibody, deposited on the surface of a bacteria, virus, immune complex, or other particulate material."^^xsd:string) AnnotationAssertion(rdfs:label "opsonin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with an opsonin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "opsonin receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "complement binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Interacting selectively and non-covalently with any component or product of the complement cascade."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "complement component C1q binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Interacting selectively and non-covalently with the C1q component of the classical complement cascade."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "complement component C3a binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Interacting selectively and non-covalently with the C3a product of the complement cascade."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "complement component C3b binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Interacting selectively and non-covalently with the C3b product of the complement cascade."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Interacting selectively and non-covalently with the iC3b product of the complement cascade."^^xsd:string) AnnotationAssertion(rdfs:label "complement component iC3b binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Interacting selectively and non-covalently with the C3dg product of the complement cascade."^^xsd:string) AnnotationAssertion(rdfs:label "complement component C3dg binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "complement component C3d binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Interacting selectively and non-covalently with the C3d product of the complement cascade."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "complement component C4b binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Interacting selectively and non-covalently with the C4b product of the classical complement cascade."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "complement component C5a binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Interacting selectively and non-covalently with the C5a product of the complement cascade."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with the C1q component of the classical complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "complement component C1q receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with the iC3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "complement component iC3b receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with the C3dg product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "complement component C3dg receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with the C3d product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "complement component C3d receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "complement component C4b receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with the C4b product of the classical complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "collectin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Interacting selectively and non-covalently with a collectin, a member of a group of structurally related pattern recognition molecules characterized by having a carbohydrate recognition domain of the C-type lectin family at the C-terminus and a collagenous domain at the N-terminus."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "collectin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with a collectin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Interacting selectively and non-covalently with a pentraxin, a member of a family of inflammatory proteins with a radially symmetric arrangement of five identical, noncovalently linked chains in a pentagonal array."^^xsd:string) AnnotationAssertion(rdfs:label "pentraxin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12072369"^^xsd:string) Annotation( "PMID:12225919"^^xsd:string) Annotation( "PMID:12507420"^^xsd:string) Annotation( "PMID:12925128"^^xsd:string) Annotation( "PMID:14523544"^^xsd:string) "Interacting selectively and non-covalently with a repeating or polymeric structure, such as a polysaccharide or peptidoglycan."^^xsd:string) AnnotationAssertion( "pattern recognition activity"^^xsd:string) AnnotationAssertion(rdfs:label "pattern binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "callose binding"^^xsd:string) AnnotationAssertion( "1,3-beta-D-glucan binding"^^xsd:string) AnnotationAssertion(rdfs:label "(1->3)-beta-D-glucan binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14707091"^^xsd:string) "Interacting selectively and non-covalently with (1->3)-beta-D-glucans."^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "zymosan binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "polysaccharide receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:18154"^^xsd:string) Annotation( "PMID:14707091"^^xsd:string) "Combining with a polysaccharide and transmitting the signal to initiate a change in cell activity. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "beta-1,3-D-glucan receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "(1->3)-beta-D-glucan receptor activity"^^xsd:string) AnnotationAssertion( "(1,3)-beta-D-glucan receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14707091"^^xsd:string) "Combining with (1->3)-beta-D-glucans to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "zymosan receptor activity"^^xsd:string) AnnotationAssertion( "1,3-beta-D-glucan receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "lipopolysaccharide receptor activity"^^xsd:string) AnnotationAssertion( "LPS receptor activity"^^xsd:string) AnnotationAssertion( "endotoxin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14609719"^^xsd:string) Annotation( "PMID:15379975"^^xsd:string) "Combining with a lipopolysaccharide and transmitting the signal across the cell membrane to initiate a change in cell activity. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "lipoarabinomannan binding"^^xsd:string) AnnotationAssertion( "LAM binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10586073"^^xsd:string) "Interacting selectively and non-covalently with lipoarabinomannan."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lipoarabinomannan receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10586073"^^xsd:string) "Combining with lipoarabinomannan and transmitting the signal to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "LAM receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose."^^xsd:string) AnnotationAssertion(rdfs:label "nucleoside binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "purine nucleoside binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyrimidine nucleoside binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with a pyrimidine nucleoside, a compound consisting of a pyrimidine base linked either to ribose or deoxyribose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.223"^^xsd:string) "alpha-N-acetylglucosaminyltransferase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.223"^^xsd:string) "UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan 4IV-alpha-N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.223"^^xsd:string) "alpha1,4-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.223"^^xsd:string) "glucuronosylgalactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.223"^^xsd:string) "UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-beta-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-D-xylosyl-proteoglycan 4IV-alpha-N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.223"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.223"^^xsd:string) "alpha-1,4-N-acetylglucosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "PMID:14555765"^^xsd:string) "Interacting selectively and non-covalently with a farnesylated protein."^^xsd:string) AnnotationAssertion(rdfs:label "farnesylated protein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a glycoprotein, a protein that contains covalently bound glycose (monosaccharide) residues. These also include proteoglycans."^^xsd:string) AnnotationAssertion(rdfs:label "glycoprotein binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "isoglobotriaosylceramide synthase"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "PMID:10854427"^^xsd:string) "Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-(1->3) linkage."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-1,3-galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide."^^xsd:string) AnnotationAssertion( "G-alpha protein subunit binding"^^xsd:string) AnnotationAssertion(rdfs:label "G-protein alpha-subunit binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fibronectin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "retinoic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protease binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with any protease or peptidase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with one of the p53 family of proteins."^^xsd:string) AnnotationAssertion(rdfs:label "p53 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with an opsin, any of a group of hydrophobic, integral membrane glycoproteins located primarily in the disc membrane of rods or cones, involved in photoreception."^^xsd:string) AnnotationAssertion( "metarhodopsin binding"^^xsd:string) AnnotationAssertion(rdfs:label "opsin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nucleobase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "adenine binding"^^xsd:string) AnnotationAssertion( "6-aminopurine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with adenine, a purine base."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cytosine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with cytosine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with guanine."^^xsd:string) AnnotationAssertion(rdfs:label "guanine binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "uracil binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with uracil."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thymine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with thymine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "purine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "purine base binding"^^xsd:string) AnnotationAssertion(rdfs:label "purine nucleobase binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:26386"^^xsd:string) Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with a purine nucleobase, an organic nitrogenous base with a purine skeleton."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "pyrimidine base binding"^^xsd:string) AnnotationAssertion(rdfs:label "pyrimidine nucleobase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "pyrimidine binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:26432"^^xsd:string) Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with a pyrimidine nucleobase, an organic nitrogenous base with a pyrimidine skeleton."^^xsd:string) AnnotationAssertion( "1,3-diazine binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-9230"^^xsd:string) "Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxybenzoate decaprenyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "polyprenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Catalysis of the transfer of multiple prenyl groups from one compound (donor) to another (acceptor)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "interleukin-33 receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-33"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-33 receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-33 receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-33 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with interleukin-33."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-33 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-33 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-33 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-33 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-33R"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with UTP, uridine 5'-triphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "UTP binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "ISBN:0124020607"^^xsd:string) "Interacting selectively and non-covalently with CTP, cytidine 5'-triphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "CTP binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "HMP-PP pyrophosphatase"^^xsd:string) AnnotationAssertion(rdfs:label "4-amino-5-hydroxymethyl-2-methylpyrimidine diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-3543"^^xsd:string) "Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate + H2O = hydroxymethylpyrimidine phosphate + phosphate + H(+)."^^xsd:string) AnnotationAssertion( "HMP-PP diphosphatase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "G quadruplex binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18294969"^^xsd:string) Annotation( "PMID:18568163"^^xsd:string) Annotation( "PMID:19330720"^^xsd:string) "Interacting selectively and non-covalently with G-quadruplex RNA structures, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "G quartet RNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "G-quartet binding"^^xsd:string) AnnotationAssertion(rdfs:label "G-quadruplex RNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "G quartet binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "steroid receptor RNA activator RNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:10199399"^^xsd:string) Annotation( "PMID:15180993"^^xsd:string) "Interacting selectively and non-covalently with the steroid receptor RNA activator RNA (SRA). SRA enhances steroid hormone receptor transcriptional activity as an RNA transcript by an indirect mechanism that does not involve SRA-steroid receptor binding."^^xsd:string) AnnotationAssertion( "SRA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "aminoacyl-tRNA hydrolysis activity"^^xsd:string) AnnotationAssertion(rdfs:label "aminoacyl-tRNA editing activity"^^xsd:string) AnnotationAssertion( "amino acid proofreading activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "PMID:14663147"^^xsd:string) Annotation( "PMID:16087889"^^xsd:string) "The hydrolysis of an incorrectly aminoacylated tRNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dystroglycan binding"^^xsd:string) AnnotationAssertion( "beta-dystroglycan binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with dystroglycan. Dystroglycan is glycoprotein found in non-muscle tissues as well as in muscle tissues, often in association with dystrophin. The native dystroglycan cleaved into two non-covalently associated subunits, alpha (N-terminal) and beta (C-terminal)."^^xsd:string) AnnotationAssertion( "alpha-dystroglycan binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with high affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "high affinity IgA receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with low affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "low affinity IgA receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with high affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "high affinity IgM receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "low affinity IgM receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with low affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Ser-tRNA(Ala) hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "PMID:21285375"^^xsd:string) "Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tRNA (adenine-C2-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:22891362"^^xsd:string) "Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(37) in tRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + C2-methyladenine(37) in a tRNA."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "molecular function"^^xsd:string) AnnotationAssertion( "molecular function unknown"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions."^^xsd:string) AnnotationAssertion(rdfs:label "molecular_function"^^xsd:string) Declaration(Class()) AnnotationAssertion(rdfs:label "nucleic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with any nucleic acid."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid)."^^xsd:string) AnnotationAssertion( "plasmid binding"^^xsd:string) AnnotationAssertion(rdfs:label "DNA binding"^^xsd:string) AnnotationAssertion( "microtubule/chromatin interaction"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix."^^xsd:string) AnnotationAssertion(rdfs:label "DNA helicase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "AT binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:2670564"^^xsd:string) "Interacting selectively and non-covalently with oligo(A) and oligo(T) tracts of DNA (AT DNA)."^^xsd:string) AnnotationAssertion(rdfs:label "AT DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bent DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:12627977"^^xsd:string) "Interacting selectively and non-covalently with DNA in a bent conformation."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "lamin/chromatin binding"^^xsd:string) AnnotationAssertion(rdfs:label "chromatin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "PMID:20404130"^^xsd:string) "Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase."^^xsd:string) AnnotationAssertion( "nuclear membrane vesicle binding to chromatin"^^xsd:string) AnnotationAssertion( "microtubule/chromatin interaction"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "damaged DNA binding"^^xsd:string) AnnotationAssertion( "DNA repair protein"^^xsd:string) AnnotationAssertion( "DNA repair enzyme"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with damaged DNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA replication origin binding"^^xsd:string) AnnotationAssertion( "ARS binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "Interacting selectively and non-covalently with the DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA clamp loader activity"^^xsd:string) AnnotationAssertion( "PCNA loading activity"^^xsd:string) AnnotationAssertion( "PCNA loading complex activity"^^xsd:string) AnnotationAssertion( "DNA clamp loading ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:16082778"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) "Interacting selectively and non-covalently with double-stranded DNA."^^xsd:string) AnnotationAssertion(rdfs:label "double-stranded DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) "dsDNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "double-stranded telomeric DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0321000382"^^xsd:string) "Interacting selectively and non-covalently with double-stranded telomere-associated DNA."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "left-handed Z-DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0716720094"^^xsd:string) "Interacting selectively and non-covalently with DNA in the Z form, i.e. a left-handed helix in which the phosphate backbone zigzags."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:9440262"^^xsd:string) "Interacting selectively and non-covalently with any P-element, a class of Drosophila transposon responsible for hybrid dysgenesis."^^xsd:string) AnnotationAssertion(rdfs:label "P-element binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "random coil DNA binding"^^xsd:string) AnnotationAssertion( "random coil binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with DNA in a random coil configuration."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "SO:0000005"^^xsd:string) "Interacting selectively and non-covalently with satellite DNA, the many tandem repeats (identical or related) of a short basic repeating unit; many have a base composition or other property different from the genome average that allows them to be separated from the bulk (main band) genomic DNA."^^xsd:string) AnnotationAssertion(rdfs:label "satellite DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "single-stranded DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "ssDNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) "Interacting selectively and non-covalently with single-stranded DNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sequence-specific DNA binding transcription factor activity"^^xsd:string) AnnotationAssertion(rdfs:label "transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity"^^xsd:string) AnnotationAssertion( "sequence-specific distal enhancer binding RNA polymerase II transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to modulate transcription by RNAP II."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "steroid hormone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:14708019"^^xsd:string) "Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "retinoic acid receptor activity"^^xsd:string) AnnotationAssertion( "vitamin A receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:1328967"^^xsd:string) "Combining with retinoic acid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. Retinoic acid is one of the forms of vitamin A."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:10213677"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with a regulatory transcription factor and also with the basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery."^^xsd:string) AnnotationAssertion( "transcriptional co-regulator"^^xsd:string) AnnotationAssertion(rdfs:label "transcription cofactor activity"^^xsd:string) AnnotationAssertion( "transcriptional cofactor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "transcription coactivator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:10213677"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery."^^xsd:string) AnnotationAssertion( "transcription co-activator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "transcription corepressor activity"^^xsd:string) AnnotationAssertion( "transcription co-repressor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:10213677"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) "Interacting selectively and non-covalently with a repressing transcription factor and also with the basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence."^^xsd:string) AnnotationAssertion(rdfs:label "telomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.49"^^xsd:string) Annotation( "PMID:11812242"^^xsd:string) "Catalysis of the extension of the 3' end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo; uses the RNA subunit of the telomerase enzyme complex as its template."^^xsd:string) AnnotationAssertion(rdfs:label "telomeric template RNA reverse transcriptase activity"^^xsd:string) AnnotationAssertion( "telomerase, catalyst"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with an RNA molecule or a portion thereof."^^xsd:string) AnnotationAssertion(rdfs:label "RNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a RNA helix."^^xsd:string) AnnotationAssertion(rdfs:label "RNA helicase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with double-stranded RNA."^^xsd:string) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) "dsRNA binding"^^xsd:string) AnnotationAssertion(rdfs:label "double-stranded RNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a double-stranded RNA molecule."^^xsd:string) AnnotationAssertion( "double-stranded RNA specific editase activity"^^xsd:string) AnnotationAssertion(rdfs:label "double-stranded RNA adenosine deaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "ssRNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with single-stranded RNA."^^xsd:string) AnnotationAssertion(rdfs:label "single-stranded RNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kmv"^^xsd:string) Annotation( "SO:0000234"^^xsd:string) "Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns."^^xsd:string) AnnotationAssertion(rdfs:label "mRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mRNA 3'-UTR binding"^^xsd:string) AnnotationAssertion( "mRNA 3' UTR binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "structural constituent of ribosome"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "The action of a molecule that contributes to the structural integrity of the ribosome."^^xsd:string) AnnotationAssertion( "ribosomal protein"^^xsd:string) AnnotationAssertion( "ribosomal RNA"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "translation initiation factor activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "translation elongation factor activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Functions in chain elongation during polypeptide synthesis at the ribosome."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198547684"^^xsd:string) "Involved in catalyzing the release of a nascent polypeptide chain from a ribosome."^^xsd:string) AnnotationAssertion(rdfs:label "translation release factor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peptidyl-prolyl cis-trans isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.8"^^xsd:string) "peptide bond isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.8"^^xsd:string) "peptidylproline cis-trans-isomerase activity"^^xsd:string) AnnotationAssertion( "cyclophilin-type peptidyl-prolyl cis-trans isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.8"^^xsd:string) "cyclophilin activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "juglone-sensitive peptidyl-prolyl cis-trans isomerase activity"^^xsd:string) AnnotationAssertion( "cis-trans proline isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.8"^^xsd:string) "Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0)."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "juglone-sensitive cis-trans proline isomerase activity"^^xsd:string) AnnotationAssertion( "FK506-sensitive peptidyl-prolyl cis-trans isomerase"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.8"^^xsd:string) "peptidylprolyl cis-trans isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.8"^^xsd:string) "rotamase activity"^^xsd:string) AnnotationAssertion( "immunophilin"^^xsd:string) AnnotationAssertion( "peptidyl-prolyl isomerase B reaction"^^xsd:string) AnnotationAssertion( "parvulin"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.8"^^xsd:string) "peptidylprolyl isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.8"^^xsd:string) "PPIase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.4.1"^^xsd:string) "protein disulfide-isomerase"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.4.1"^^xsd:string) "S-S rearrangase activity"^^xsd:string) AnnotationAssertion( "protein thiol-disulphide exchange"^^xsd:string) AnnotationAssertion( "protein thiol-disulfide exchange"^^xsd:string) AnnotationAssertion( "protein cysteine-thiol oxidation"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.4.1"^^xsd:string) "protein disulfide-isomerase reaction"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.4.1"^^xsd:string) "Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins."^^xsd:string) AnnotationAssertion( "disulphide bond biosynthesis"^^xsd:string) AnnotationAssertion( "disulphide bond formation"^^xsd:string) AnnotationAssertion( "protein disulphide isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein disulfide isomerase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0815316194"^^xsd:string) "Catalysis of movement along a polymeric molecule such as a microfilament or microtubule, coupled to the hydrolysis of a nucleoside triphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "molecular motor"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "dynein ATPase activity"^^xsd:string) AnnotationAssertion( "axonemal motor activity"^^xsd:string) AnnotationAssertion(rdfs:label "microtubule motor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0815316194"^^xsd:string) "Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP)."^^xsd:string) AnnotationAssertion( "kinetochore motor activity"^^xsd:string) AnnotationAssertion( "kinesin motor activity"^^xsd:string) AnnotationAssertion( "dynein"^^xsd:string) AnnotationAssertion( "kinesin"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "actin binding"^^xsd:string) AnnotationAssertion( "membrane associated actin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:clt"^^xsd:string) "Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with monomeric actin, also known as G-actin."^^xsd:string) AnnotationAssertion(rdfs:label "actin monomer binding"^^xsd:string) AnnotationAssertion( "G actin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "actin lateral binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with an actin filament along its length."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.17"^^xsd:string) "Catalysis of the hydrolysis of the beta-(1->4) linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins."^^xsd:string) AnnotationAssertion( "muramidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.17"^^xsd:string) "lysozyme g"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.17"^^xsd:string) "L-7001"^^xsd:string) AnnotationAssertion( "mucopeptide N-acetylmuramoylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.17"^^xsd:string) "globulin G1"^^xsd:string) AnnotationAssertion(rdfs:label "lysozyme activity"^^xsd:string) AnnotationAssertion( "1,4-N-acetylmuramidase activity"^^xsd:string) AnnotationAssertion( "mucopeptide glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.17"^^xsd:string) "globulin G"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.17"^^xsd:string) "peptidoglycan N-acetylmuramoylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.17"^^xsd:string) "PR1-lysozyme"^^xsd:string) AnnotationAssertion( "N,O-diacetylmuramidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.2.13"^^xsd:string) "glutaminylpeptide gamma-glutamyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.13"^^xsd:string) "fibrin stabilizing factor"^^xsd:string) AnnotationAssertion( "fibrinoligase activity"^^xsd:string) AnnotationAssertion( "TGase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.13"^^xsd:string) "R-glutaminyl-peptide:amine gamma-glutamyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.13"^^xsd:string) "polyamine transglutaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.13"^^xsd:string) "tissue transglutaminase"^^xsd:string) AnnotationAssertion( "transglutaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.13"^^xsd:string) "protein-glutamine:amine gamma-glutamyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.13"^^xsd:string) Annotation( "RESID:AA0124"^^xsd:string) "Catalysis of the reaction: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3. This reaction is the formation of the N6-(L-isoglutamyl)-L-lysine isopeptide, resulting in cross-linking polypeptide chains; the gamma-carboxamide groups of peptidyl-glutamine residues act as acyl donors, and the 6-amino-groups of peptidyl-lysine residues act as acceptors, to give intra- and intermolecular N6-(5-glutamyl)lysine cross-links."^^xsd:string) AnnotationAssertion(rdfs:label "protein-glutamine gamma-glutamyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.13"^^xsd:string) "factor XIIIa"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "B cell receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0721662544"^^xsd:string) "Interacting selectively and non-covalently with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen."^^xsd:string) AnnotationAssertion(rdfs:label "antigen binding"^^xsd:string) AnnotationAssertion( "antibody"^^xsd:string) AnnotationAssertion( "immunoglobulin"^^xsd:string) AnnotationAssertion( "opsonin activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic."^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "catalytic activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "trehalosephosphate-UDP glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.15"^^xsd:string) "alpha,alpha-trehalose phosphate synthase (UDP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.15"^^xsd:string) "UDPglucose-glucose-phosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "trehalose-phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.15"^^xsd:string) "UDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.15"^^xsd:string) "trehalose phosphate synthase activity"^^xsd:string) AnnotationAssertion( "trehalosephosphate-UDP glucosyl transferase activity"^^xsd:string) AnnotationAssertion( "UDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "transglucosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.15"^^xsd:string) "trehalose-P synthetase activity"^^xsd:string) AnnotationAssertion( "trehalose 6-phosphate synthase activity"^^xsd:string) AnnotationAssertion( "trehalose 6-phosphate synthetase activity"^^xsd:string) AnnotationAssertion( "UDP-glucose-glucose-phosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.15"^^xsd:string) "Catalysis of the reaction: UDP-glucose + D-glucose-6-phosphate = UDP + alpha,alpha-trehalose-6-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.15"^^xsd:string) "phosphotrehalose-uridine diphosphate transglucosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.15"^^xsd:string) "UDP-glucose-glucosephosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.15"^^xsd:string) "trehalose phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.15"^^xsd:string) "uridine diphosphoglucose phosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.15"^^xsd:string) "trehalose phosphate-uridine diphosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "trehalose-phosphate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction involving an alpha-ketoacid."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-ketoacid dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "alpha-1,3-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.101"^^xsd:string) "uridine diphosphoacetylglucosamine-alpha-1,3-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.101"^^xsd:string) "GNTI activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.101"^^xsd:string) "UDP-N-acetyl-D-glucosamine:3-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.101"^^xsd:string) "UDP-N-acetylglucosaminyl:alpha-1,3-D-mannoside-beta-1,2-N-acetylglucosaminyltransferase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.101"^^xsd:string) "N-acetylglucosaminyltransferase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.101"^^xsd:string) "alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.101"^^xsd:string) Annotation( "RHEA:11459"^^xsd:string) "Catalysis of the reaction: 3-(alpha-D-mannosyl)-beta-D-mannosyl-R + UDP-N-acetyl-alpha-D-glucosamine = 3-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R + H(+) + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.101"^^xsd:string) "N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.101"^^xsd:string) "GnTI"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.101"^^xsd:string) "alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.101"^^xsd:string) "UDP-N-acetylglucosaminyl:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.99.8"^^xsd:string) "CMP-NeuAc:LM1 alpha-(2->8)-sialyltranferase activity"^^xsd:string) AnnotationAssertion( "alpha-N-acetylneuraminide alpha-2,8-sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.8"^^xsd:string) "ganglioside GD3 synthetase sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.8"^^xsd:string) "SAT-2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.8"^^xsd:string) "CMP-NeuAc:LM1(alpha-2,8) sialyltranferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.8"^^xsd:string) "ganglioside GD3 synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.8"^^xsd:string) "cytidine monophosphoacetylneuraminate-ganglioside GM3"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.8"^^xsd:string) "Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.8"^^xsd:string) "GD3 synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.8"^^xsd:string) "alpha-2,8-sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.8"^^xsd:string) "CMP-N-acetylneuraminate:alpha-N-acetylneuraminyl-2,3-beta-D-galactoside alpha-2,8-N-acetylneuraminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.102"^^xsd:string) "beta6-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.102"^^xsd:string) "uridine diphosphoacetylglucosamine-mucin beta-(1,6)-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.102"^^xsd:string) "beta(6)-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.102"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-D-galactosaminyl-R."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.102"^^xsd:string) "core 2 acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.102"^^xsd:string) "core 6-beta-GlcNAc-transferase A"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.102"^^xsd:string) "UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.102"^^xsd:string) "O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.102"^^xsd:string) "uridine diphosphoacetylglucosamine-mucin beta-(1->6)-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.144"^^xsd:string) "N-acetylglucosaminyltransferase III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.144"^^xsd:string) "beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.144"^^xsd:string) "uridine diphosphoacetylglucosamine-glycopeptide beta-4-acetylglucosaminyltransferase III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.144"^^xsd:string) "N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.144"^^xsd:string) "beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.144"^^xsd:string) "GnTIII activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.144"^^xsd:string) "uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase III"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.144"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-mannosyl-R = UDP + 4-(N-acetyl-beta-D-glucosaminyl)-beta-D-mannosyl-R."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.144"^^xsd:string) "UDP-N-acetyl-D-glucosamine:beta-D-mannosyl-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.38"^^xsd:string) "Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide."^^xsd:string) AnnotationAssertion(rdfs:label "beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.38"^^xsd:string) "UDP-galactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.38"^^xsd:string) "GalT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.38"^^xsd:string) "UDP-D-xylose:glycoprotein (D-xylose to the 3,6-disubstituted mannose of 4-N-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 2-beta-D-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.38"^^xsd:string) "thyroid glycoprotein beta-galactosyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.38"^^xsd:string) "glycoprotein 4-beta-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.38"^^xsd:string) "beta-N-acetyl-beta-(1,4)-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.38"^^xsd:string) "glycoprotein beta-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.38"^^xsd:string) "UDP-galactose--glycoprotein galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.38"^^xsd:string) "UDP-D-xylose:glycoprotein (D-xylose to the 3,6-disubstituted mannose of N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 2-beta-D-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.38"^^xsd:string) "thyroid galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.38"^^xsd:string) "UDPgalactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.38"^^xsd:string) "glycoprotein 4-beta-galactosyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.38"^^xsd:string) "uridine diphosphogalactose-glycoprotein galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.38"^^xsd:string) "beta-N-acetyl-beta-1,4-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.38"^^xsd:string) "UDPgalactose-glycoprotein galactosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "PMID:12957543"^^xsd:string) "Catalysis of the reaction: N-beta-alanyl dopamine + H2O = dopamine + beta-alanine."^^xsd:string) AnnotationAssertion( "NBAD hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-alanyl-dopamine hydrolase activity"^^xsd:string) AnnotationAssertion( "N-beta-alanyl-dopamine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "N-beta-alanyl dopamine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "PMID:12957543"^^xsd:string) "Catalysis of the synthesis of beta-alanyl-dopamine from the precursor dopamine (3,4-dihydroxyphenylethylamine)."^^xsd:string) AnnotationAssertion(rdfs:label "beta-alanyl-dopamine synthase activity"^^xsd:string) AnnotationAssertion( "NBAD transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.36"^^xsd:string) "carotene dioxygenase activity"^^xsd:string) AnnotationAssertion( "beta-carotene 15,15'-dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-carotene 15,15'-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.36"^^xsd:string) "beta-carotene:oxygen 15,15'-oxidoreductase (bond-cleaving)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.36"^^xsd:string) "carotene 15,15'-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.36"^^xsd:string) Annotation( "RHEA:10407"^^xsd:string) "Catalysis of the reaction: beta-carotene + O(2) = 2 retinal."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.99.1"^^xsd:string) "Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.1"^^xsd:string) "CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine alpha-2,6-N-acetylneuraminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.1"^^xsd:string) "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase activity"^^xsd:string) AnnotationAssertion( "beta-galactosamide alpha-2,6-sialyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-galactoside alpha-2,6-sialyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.99.4"^^xsd:string) "Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R."^^xsd:string) AnnotationAssertion(rdfs:label "beta-galactoside (CMP) alpha-2,3-sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.4"^^xsd:string) "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.4"^^xsd:string) "CMP-N-acetylneuraminate:beta-D-galactoside alpha-2,3-N-acetylneuraminyl-transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-ureidopropionase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.6"^^xsd:string) "N-carbamoyl-beta-alanine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.6"^^xsd:string) "Catalysis of the reaction: N-carbamoyl-beta-alanine + H2O = beta-alanine + CO2 + NH3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.41"^^xsd:string) "S-adenosyl-L-methionine:zymosterol 24-C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.41"^^xsd:string) "S-adenosyl-4-methionine:sterol Delta(24)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.41"^^xsd:string) "delta(24)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.41"^^xsd:string) "zymosterol-24-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.41"^^xsd:string) "24-sterol C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.41"^^xsd:string) "phytosterol methyltransferase activity"^^xsd:string) AnnotationAssertion( "delta(24)-sterol C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.41"^^xsd:string) "SMT1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.41"^^xsd:string) "S-adenosyl-4-methionine:sterol delta24-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.41"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + 5-alpha-cholest-8,24-dien-3-beta-ol = S-adenosyl-L-homocysteine + 24-methylene-5-alpha-cholest-8-en-3-beta-ol."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.41"^^xsd:string) "delta(24)-sterol methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.41"^^xsd:string) "S-adenosyl-L-methionine:Delta(24(23))-sterol methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sterol 24-C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.41"^^xsd:string) "delta24-sterol methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.41"^^xsd:string) "delta24-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.41"^^xsd:string) "S-adenosyl-L-methionine:Delta24(23)-sterol methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.2.4"^^xsd:string) "gamma-glutamyl-amino acid cyclotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.4"^^xsd:string) "gamma-L-glutamylcyclotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.4"^^xsd:string) "L-glutamic cyclase activity"^^xsd:string) AnnotationAssertion(rdfs:label "gamma-glutamylcyclotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.4"^^xsd:string) "Catalysis of the reaction: (5-L-glutamyl)-L-amino acid = 5-oxoproline + L-amino acid."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.4"^^xsd:string) "(5-L-glutamyl)-L-amino-acid 5-glutamyltransferase (cyclizing)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "gamma-glutamyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.2"^^xsd:string) "alpha-glutamyl transpeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.2"^^xsd:string) "Catalysis of the reaction: (5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl-amino acid."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.2"^^xsd:string) "gamma-GT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.2"^^xsd:string) "gamma-GPT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.2"^^xsd:string) "(5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.2"^^xsd:string) "L-gamma-glutamyl transpeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.2"^^xsd:string) "gamma-glutamyl peptidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.2"^^xsd:string) "L-glutamyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.2"^^xsd:string) "gamma-glutamyl transpeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.2"^^xsd:string) "L-gamma-glutamyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.2"^^xsd:string) "gamma-GTP"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.2"^^xsd:string) "glutamyl transpeptidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.51"^^xsd:string) "1-acyl-sn-glycerol 3-phosphate acyltransferase activity"^^xsd:string) AnnotationAssertion( "lysophosphatidate acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-acylglycerol-3-phosphate O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.51"^^xsd:string) "1-acylglycerophosphate acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.51"^^xsd:string) "1-acylglycero-3-phosphate acyltransferase activity"^^xsd:string) AnnotationAssertion( "1-acyl-sn-glycerol-3-phosphate acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.51"^^xsd:string) "1-acyl-sn-glycero-3-phosphate acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.51"^^xsd:string) "acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.51"^^xsd:string) "lysophosphatidic acid-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.51"^^xsd:string) "1-acylglycerolphosphate acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.51"^^xsd:string) Annotation( "GOC:ab"^^xsd:string) "Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.12"^^xsd:string) "pyrroline-5-carboxylic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-pyrroline-5-carboxylate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.12"^^xsd:string) "1-pyrroline-5-carboxylate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.12"^^xsd:string) "pyrroline-5-carboxylate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.12"^^xsd:string) "L-pyrroline-5-carboxylate-NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.12"^^xsd:string) "delta1-pyrroline-5-carboxylate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.12"^^xsd:string) "1-pyrroline dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.12"^^xsd:string) "Catalysis of the reaction: 1-pyrroline-5-carboxylate + NAD+ + H2O = L-glutamate + NADH + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.34"^^xsd:string) "UDP-glucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.34"^^xsd:string) "1,3-beta-glucan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.34"^^xsd:string) "UDP-glucose-beta-glucan glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.34"^^xsd:string) "(1,3)-beta-glucan (callose) synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.34"^^xsd:string) "UDP-glucose:(1,3)beta-glucan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.34"^^xsd:string) "1,3-beta-D-glucan-UDP glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1,3-beta-D-glucan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.34"^^xsd:string) "1,3-beta-glucan-uridine diphosphoglucosyltransferase activity"^^xsd:string) AnnotationAssertion( "beta-1,3-glucan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.34"^^xsd:string) "beta-1,3-glucan synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.34"^^xsd:string) "1,3-beta-D-glucan synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.34"^^xsd:string) "paramylon synthetase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.34"^^xsd:string) "UDPglucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.34"^^xsd:string) "uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "callose synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.34"^^xsd:string) "UDP-glucose-1,3-beta-glucan glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.34"^^xsd:string) "GS-II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.34"^^xsd:string) "UDPglucose-1,3-beta-D-glucan glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.34"^^xsd:string) "callose synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.34"^^xsd:string) "Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + [(1->3)-beta-D-glucosyl](n+1)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.34"^^xsd:string) "UDP-glucose-1,3-beta-D-glucan glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.18"^^xsd:string) "plant branching enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.18"^^xsd:string) "starch branching enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.18"^^xsd:string) "Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.18"^^xsd:string) "glycogen branching enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.18"^^xsd:string) "branching glycosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.18"^^xsd:string) "amylo-(1,4->1,6)-transglycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.18"^^xsd:string) "enzyme Q"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.18"^^xsd:string) "branching enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.18"^^xsd:string) "alpha-glucan-branching glycosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.18"^^xsd:string) "alpha-1,4-glucan:alpha-1,4-glucan-6-glycosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.18"^^xsd:string) "amylose isomerase activity"^^xsd:string) AnnotationAssertion( "1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-alpha-D-(1,4-alpha-D-glucano)-transferase activity"^^xsd:string) AnnotationAssertion( "1,4-glucan-6-(1,4-glucano)-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.18"^^xsd:string) "Q-enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.18"^^xsd:string) "amylo-(1,4 to 1,6)transglucosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1,4-alpha-glucan branching enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.18"^^xsd:string) "glucosan transglycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.18"^^xsd:string) "enzymatic branching factor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.146"^^xsd:string) "11beta-hydroxysteroid dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.146"^^xsd:string) Annotation( "PMID:15761036"^^xsd:string) "Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD(P)+ = an 11-oxosteroid + NAD(P)H + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.146"^^xsd:string) "corticosteroid 11-reductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.146"^^xsd:string) "dehydrogenase, 11beta-hydroxy steroid"^^xsd:string) AnnotationAssertion(rdfs:label "11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.146"^^xsd:string) "corticosteroid 11beta-dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.146"^^xsd:string) "11beta-hydroxy steroid dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.146"^^xsd:string) "beta-hydroxysteroid dehydrogenase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.22"^^xsd:string) "acyl-CoA:2-acylglycerol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.22"^^xsd:string) "acylglycerol palmitoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.22"^^xsd:string) "monoglyceride acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.22"^^xsd:string) "Catalysis of the reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.22"^^xsd:string) "acyl coenzyme A-monoglyceride acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-acylglycerol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.22"^^xsd:string) "monoacylglycerol acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.47"^^xsd:string) "PAF acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.47"^^xsd:string) "LDL-PLA2"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.47"^^xsd:string) "1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase activity"^^xsd:string) AnnotationAssertion( "2-acetyl-1-alkylglycerophosphocholine esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.47"^^xsd:string) "LDL-associated phospholipase A(2) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.47"^^xsd:string) "platelet-activating factor acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.47"^^xsd:string) "PAF 2-acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.47"^^xsd:string) "alkylacetyl-GPC:acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.47"^^xsd:string) "1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.47"^^xsd:string) "LDL-associated phospholipase A2"^^xsd:string) AnnotationAssertion(rdfs:label "1-alkyl-2-acetylglycerophosphocholine esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.47"^^xsd:string) "Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.47"^^xsd:string) "LDL-PLA(2) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.6.3"^^xsd:string) "H2-pteridine-CH2OH pyrophosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.3"^^xsd:string) "7,8-dihydro-6-hydroxymethylpterin diphosphokinase activity"^^xsd:string) AnnotationAssertion( "2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.3"^^xsd:string) "hydroxymethyldihydropteridine pyrophosphokinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.3"^^xsd:string) "HPPK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.3"^^xsd:string) Annotation( "RHEA:11415"^^xsd:string) "Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP = (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate + AMP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.3"^^xsd:string) "6-hydroxymethyl-7,8-dihydropterin diphosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.3"^^xsd:string) "7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.3"^^xsd:string) "ATP:2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine 6'-diphosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.3"^^xsd:string) "6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.3"^^xsd:string) "7,8-dihydroxymethylpterin-pyrophosphokinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "KDPH synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "phosphoenolpyruvate:D-erythrose-4-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "KDPH synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "phospho-2-dehydro-3-deoxyheptonate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "D-erythrose-4-phosphate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "DS-Co activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "7-phospho-2-keto-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "phospho-2-oxo-3-deoxyheptonate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "3-deoxy-D-arabino-heptolosonate-7-phosphate synthetase activity"^^xsd:string) AnnotationAssertion( "2-dehydro-3-deoxyphosphoheptonate aldolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-deoxy-7-phosphoheptulonate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) Annotation( "RHEA:14720"^^xsd:string) "Catalysis of the reaction: D-erythrose 4-phosphate + H(2)O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "2-dehydro-3-deoxy-phosphoheptonate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "deoxy-D-arabino-heptulosonate-7-phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "DS-Mn activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "DHAP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "DAH7-P synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "phospho-2-keto-3-deoxyheptonate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "phospho-2-keto-3-deoxyheptanoate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "2-keto-3-deoxy-D-arabino-heptonic acid 7-phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "phospho-2-keto-3-deoxyheptonic aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "3-deoxy-D-arabino-2-heptulosonic acid 7-phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.54"^^xsd:string) "DAHP synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.68"^^xsd:string) "2-deoxy-D-glucose-6-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-deoxyglucose-6-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.68"^^xsd:string) "2-deoxyglucose-6-phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.68"^^xsd:string) "Catalysis of the reaction: 2-deoxy-D-glucose-6-phosphate + H2O = 2-deoxy-D-glucose + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.45"^^xsd:string) "cerebroside synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.45"^^xsd:string) "UDPgalactose:2-2-hydroxyacylsphingosine galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.45"^^xsd:string) "UDP-galactose:2-(2-hydroxyacyl)sphingosine 1-beta-D-galactosyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.45"^^xsd:string) "UDPgalactose-2-hydroxyacylsphingosine galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.45"^^xsd:string) "UDPgalactose:2-(2-hydroxyacyl)sphingosine 1-beta-D-galactosyl-transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.45"^^xsd:string) "UDPgalactose:ceramide galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.45"^^xsd:string) "UDP-galactose-ceramide galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.45"^^xsd:string) "Catalysis of the reaction: UDP-galactose + 2-(2-hydroxyacyl)sphingosine = UDP + 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.45"^^xsd:string) "uridine diphosphogalactose-2-hydroxyacylsphingosine galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-isopropylmalate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.13"^^xsd:string) "alpha-IPM synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.13"^^xsd:string) "isopropylmalate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.13"^^xsd:string) "alpha-isopropylmalate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.13"^^xsd:string) "3-carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.13"^^xsd:string) "isopropylmalate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.13"^^xsd:string) Annotation( "RHEA:21527"^^xsd:string) "Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H(2)O = (2S)-2-isopropylmalate + CoA + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.13"^^xsd:string) "alpha-isopropylmalate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.13"^^xsd:string) "acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.13"^^xsd:string) "alpha-isopropylmalic synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.99.12"^^xsd:string) "2-methylbutanoyl-CoA:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.12"^^xsd:string) "Catalysis of the reaction: 2-methylbutanoyl-CoA + acceptor = 2-methylbut-2-enoyl-CoA + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.12"^^xsd:string) "branched-chain acyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-methylacyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.12"^^xsd:string) "2-methyl branched chain acyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.12"^^xsd:string) "2-methylbutanoyl-CoA:(acceptor) oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.145"^^xsd:string) "3-beta-hydroxy-5-ene steroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.145"^^xsd:string) "3beta-hydroxy-delta5-steroid:NAD+ 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.145"^^xsd:string) "Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.145"^^xsd:string) "3beta-hydroxy-delta5-C27-steroid dehydrogenase/isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.145"^^xsd:string) "3beta-HSDH"^^xsd:string) AnnotationAssertion(rdfs:label "3-beta-hydroxy-delta5-steroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.145"^^xsd:string) "3beta-hydroxy-delta5-C27-steroid oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.145"^^xsd:string) "3beta-hydroxy steroid dehydrogenase/isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.145"^^xsd:string) "progesterone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.145"^^xsd:string) "steroid-delta5-3beta-ol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.145"^^xsd:string) "3beta-hydroxy-5-ene-steroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.145"^^xsd:string) "delta5-3beta-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.145"^^xsd:string) "5-ene-3-beta-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.145"^^xsd:string) "3beta-hydroxy-delta5-steroid dehydrogenase activity"^^xsd:string) AnnotationAssertion( "3-beta-hydroxy-D5-steroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.145"^^xsd:string) "3beta-hydroxy-5-ene steroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.145"^^xsd:string) "3beta-hydroxy-5-ene-steroid oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.10"^^xsd:string) "5-dehydroquinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.10"^^xsd:string) "DHQase"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.10"^^xsd:string) "3-dehydroquinate hydro-lyase (3-dehydroshikimate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "3-dehydroquinate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.10"^^xsd:string) "dehydroquinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.10"^^xsd:string) "5-dehydroquinate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.10"^^xsd:string) "3-dehydroquinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.10"^^xsd:string) Annotation( "RHEA:21099"^^xsd:string) "Catalysis of the reaction: 3-dehydroquinate = 3-dehydroshikimate + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.10"^^xsd:string) "3-dehydroquinate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.10"^^xsd:string) "3-dehydroquinate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.10"^^xsd:string) "5-dehydroquinate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.10"^^xsd:string) "dehydroquinate dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.4"^^xsd:string) "3-deoxy-arabino-heptulonate-7-phosphate phosphate-lyase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.4"^^xsd:string) "5-dehydroquinic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.4"^^xsd:string) "3-deoxy-arabino-heptulonate-7-phosphate phosphate-lyase (cyclizing; 3-dehydroquinate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17586643"^^xsd:string) "DHQS"^^xsd:string) AnnotationAssertion(rdfs:label "3-dehydroquinate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.4"^^xsd:string) Annotation( "RHEA:21971"^^xsd:string) "Catalysis of the reaction: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.4"^^xsd:string) "5-dehydroquinate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.4"^^xsd:string) "dehydroquinate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17586643"^^xsd:string) "DHQ synthase"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.4"^^xsd:string) "3-deoxy-arabino-heptulosonate-7-phosphate phosphate-lyase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.4"^^xsd:string) "3-dehydroquinate synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.35"^^xsd:string) "beta-hydroxyacylcoenzyme A dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.35"^^xsd:string) "beta-ketoacyl-CoA reductase"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxyacyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.35"^^xsd:string) "L-3-hydroxyacyl coenzyme A dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.35"^^xsd:string) "beta-hydroxybutyrylcoenzyme A dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.35"^^xsd:string) "beta-hydroxyacyl-coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.35"^^xsd:string) "beta-keto-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19685079"^^xsd:string) "3-oxoacyl-thioester reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.35"^^xsd:string) "L-3-hydroxyacyl CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.35"^^xsd:string) "Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.35"^^xsd:string) "beta-hydroxyacyl dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-hydroxybutyrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.30"^^xsd:string) Annotation( "RHEA:20524"^^xsd:string) "Catalysis of the reaction: (R)-3-hydroxybutanoate + NAD(+) = acetoacetate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.30"^^xsd:string) "D-beta-hydroxybutyrate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.55"^^xsd:string) Annotation( "RHEA:17852"^^xsd:string) "Catalysis of the reaction: (R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.55"^^xsd:string) "crotonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.55"^^xsd:string) "(3R)-3-hydroxybutanoyl-CoA hydro-lyase (crotonoyl-CoA-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.55"^^xsd:string) "(3R)-3-hydroxybutanoyl-CoA hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.55"^^xsd:string) "enoyl coenzyme A hydrase (D)"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxybutyryl-CoA dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.55"^^xsd:string) "D-3-hydroxybutyryl-CoA dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.55"^^xsd:string) "D-3-hydroxybutyryl coenzyme A dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.2.4"^^xsd:string) "HIB CoA deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.4"^^xsd:string) "3-hydroxy-isobutyryl CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.4"^^xsd:string) "Catalysis of the reaction: 3-hydroxy-2-methylpropanoyl-CoA + H2O = CoA + 3-hydroxy-2-methylpropanoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.4"^^xsd:string) "3-hydroxy-2-methylpropanoyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxyisobutyryl-CoA hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.33"^^xsd:string) "(2R,3S)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.33"^^xsd:string) "(2R,3S)-3-isopropylmalate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.33"^^xsd:string) "Catalysis of the reaction: 3-isopropylmalate = 2-isopropylmaleate + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.33"^^xsd:string) "beta-isopropylmalate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.33"^^xsd:string) "alpha-isopropylmalate isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-isopropylmalate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.33"^^xsd:string) "isopropylmalate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.33"^^xsd:string) "alpha-IPM isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.85"^^xsd:string) "3-carboxy-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.85"^^xsd:string) "Catalysis of the reaction: 3-carboxy-2-hydroxy-4-methylpentanoate + NAD+ = 3-carboxy-4-methyl-2-oxopentanoate + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.85"^^xsd:string) "beta-isopropylmalic enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.85"^^xsd:string) "beta-IPM dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.85"^^xsd:string) "threo-Ds-3-isopropylmalate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.85"^^xsd:string) "beta-isopropylmalate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.85"^^xsd:string) "(2R,3S)-3-isopropylmalate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.85"^^xsd:string) "IMDH activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-isopropylmalate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.85"^^xsd:string) "IPMDH"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "Catalysis of the reaction: 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)dihydrolipoamide + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "alpha-ketoisocaproate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "2-oxoisovalerate (lipoate) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "dehydrogenase, branched chain alpha-keto acid activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "alpha-ketoisocaproic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "2-oxoisocaproate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "3-methyl-2-oxobutanoate:lipoamide oxidoreductase (decarboxylating and acceptor-2-methylpropanoylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "branched-chain (-2-oxoacid) dehydrogenase (BCD) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "3-methyl-2-oxobutanoate:dihydrolipoyllysine-residue (2-methylpropanoyl)transferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "alpha-ketoisovalerate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "branched-chain 2-keto acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "branched-chain 2-oxo acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "branched-chain keto acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "branched-chain alpha-keto acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "branched chain keto acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "dehydrogenase, 2-oxoisovalerate (lipoate) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "branched-chain alpha-oxo acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "alpha-keto-alpha-methylvalerate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "BCKDH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "BCOAD activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "alpha-oxoisocaproate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "branched-chain ketoacid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "3-methyl-2-oxobutanoate dehydrogenase (lipoamide) activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.4"^^xsd:string) "alpha-ketoisocaproic-alpha-keto-alpha-methylvaleric dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.2.11"^^xsd:string) "alpha-ketoisovalerate hydroxymethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.11"^^xsd:string) "ketopantoate hydroxymethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.11"^^xsd:string) "oxopantoate hydroxymethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.11"^^xsd:string) "5,10-methylene tetrahydrofolate:alpha-ketoisovalerate hydroxymethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.11"^^xsd:string) "dehydropantoate hydroxymethyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-methyl-2-oxobutanoate hydroxymethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.11"^^xsd:string) "5,10-methylenetetrahydrofolate:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.11"^^xsd:string) "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "3-oxo-5alpha-steroid 4-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "3-keto-delta4-steroid-5alpha-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "steroid delta4-5alpha-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "5alpha-reductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "Catalysis of the reaction: a 3-oxo-5-alpha-steroid + acceptor = a 3-oxo-delta(4)-steroid + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "delta4-3-oxosteroid-5alpha-reductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "3-oxo-5alpha-steroid:acceptor delta4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "delta4-3-keto steroid 5alpha-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "steroid 5 alpha reductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "3-oxosteroid delta4-dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "delta4-3-oxo steroid reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "4-ene-3-ketosteroid-5alpha-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "delta4-5alpha-dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-oxo-5-alpha-steroid 4-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "delta4-3-ketosteroid5alpha-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "3-oxo-5alpha-steroid delta4-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "steroid 5alpha-reductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "3-oxo-5alpha-steroid:(acceptor) delta4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "steroid 5-alpha-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.5"^^xsd:string) "testosterone 5alpha-reductase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.19"^^xsd:string) "3-enol-pyruvoylshikimate-5-phosphate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-phosphoshikimate 1-carboxyvinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.19"^^xsd:string) Annotation( "RHEA:21259"^^xsd:string) "Catalysis of the reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.19"^^xsd:string) "5-enolpyruvylshikimate-3-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.19"^^xsd:string) "phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.19"^^xsd:string) "EPSP synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "gamma-aminobutyric acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "GABA transferase activity"^^xsd:string) AnnotationAssertion( "4-aminobutyrate aminotransferase activity"^^xsd:string) AnnotationAssertion( "GABA transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "gamma-aminobutyric acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "aminobutyrate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "gamma-aminobutyrate aminotransaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "4-aminobutyric acid aminotransferase activity"^^xsd:string) AnnotationAssertion( "4-aminobutanoate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "beta-alanine-oxoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "gamma-aminobutyric transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "beta-alanine--oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "gamma-amino-N-butyrate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "beta-alanine aminotransferase"^^xsd:string) AnnotationAssertion(rdfs:label "4-aminobutyrate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "glutamate-succinic semialdehyde transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "GABA aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: 4-aminobutanoate + amino group acceptor = succinate semialdehyde + amino acid."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "aminobutyrate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "gamma-aminobutyrate transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-hydroxyphenylpyruvate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.27"^^xsd:string) "p-hydroxyphenylpyruvate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.27"^^xsd:string) "p-hydroxyphenylpyruvic oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.27"^^xsd:string) "4-hydroxyphenylpyruvate hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.27"^^xsd:string) "p-hydroxyphenylpyruvic acid hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.27"^^xsd:string) "p-hydroxyphenylpyruvic hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.27"^^xsd:string) "4-hydroxyphenylpyruvic acid dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.27"^^xsd:string) "p-hydroxyphenylpyruvate hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.27"^^xsd:string) "Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.27"^^xsd:string) "4-hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating, decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.27"^^xsd:string) "p-hydroxyphenylpyruvate oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "aminolevulinic acid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "delta-aminolevulinic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "aminolevulinate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "ALA synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "delta-aminolevulinate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "delta-ALA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "alpha-aminolevulinic acid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "aminolevulinate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "5-aminolevulinic acid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "succinyl-CoA:glycine C-succinyltransferase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "delta-aminolevulinic acid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "aminolevulinic synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "5-aminolevulinate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "aminolevulinic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) Annotation( "RHEA:12924"^^xsd:string) "Catalysis of the reaction: glycine + H(+) + succinyl-CoA = 5-aminolevulinate + CO(2) + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "ALA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "5-aminolevulinic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "ALAS activity"^^xsd:string) AnnotationAssertion(rdfs:label "5-aminolevulinate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "delta-aminolevulinate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.37"^^xsd:string) "delta-aminolevulinic synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.14"^^xsd:string) "5-methyltetrahydropteroyltri-L-glutamate:L-homocysteine S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.14"^^xsd:string) "methyltransferase, tetrahydropteroylglutamate-homocysteine transmethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.14"^^xsd:string) Annotation( "RHEA:21199"^^xsd:string) "Catalysis of the reaction: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.14"^^xsd:string) "MetE"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.14"^^xsd:string) "methionine synthase (cobalamin-independent) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.14"^^xsd:string) "tetrahydropteroylglutamate-homocysteine transmethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.14"^^xsd:string) "methyltetrahydropteroylpolyglutamate:homocysteine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.14"^^xsd:string) "homocysteine methylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.14"^^xsd:string) "cobalamin-independent methionine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.14"^^xsd:string) "tetrahydropteroyltriglutamate methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.11"^^xsd:string) "ATP:D-fructose-6-phosphate 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.11"^^xsd:string) "phosphofructokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.11"^^xsd:string) "Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.11"^^xsd:string) "nucleotide triphosphate-dependent phosphofructokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.11"^^xsd:string) "phospho-1,6-fructokinase activity"^^xsd:string) AnnotationAssertion( "6-phosphofructokinase reduction"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.11"^^xsd:string) "fructose 6-phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.11"^^xsd:string) "phosphohexokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.11"^^xsd:string) "ATP-dependent phosphofructokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.11"^^xsd:string) "6-phosphofructose 1-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.11"^^xsd:string) "PFK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.11"^^xsd:string) "D-fructose-6-phosphate 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.11"^^xsd:string) "phosphofructokinase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.11"^^xsd:string) "fructose 6-phosphokinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "6-phosphofructokinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.105"^^xsd:string) "6-phosphofructose 2-kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "6-phosphofructo-2-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.105"^^xsd:string) "phosphofructokinase 2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.105"^^xsd:string) "ATP:D-fructose-6-phosphate 2-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.105"^^xsd:string) Annotation( "RHEA:15656"^^xsd:string) "Catalysis of the reaction: beta-D-fructose 6-phosphate + ATP = beta-D-fructose 2,6-bisphosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.105"^^xsd:string) "ATP:beta-D-fructose-6-phosphate 2-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.105"^^xsd:string) "6-phosphofructo-2-kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.105"^^xsd:string) "fructose 6-phosphate 2-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.12"^^xsd:string) "6-pyruvoyl tetrahydrobiopterin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.12"^^xsd:string) Annotation( "RHEA:22051"^^xsd:string) "Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + triphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.12"^^xsd:string) "PTPS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.12"^^xsd:string) "2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate-lyase (6-pyruvoyl-5,6,7,8-tetrahydropterin-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "6-pyruvoyltetrahydropterin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.12"^^xsd:string) "2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.19"^^xsd:string) "nomega-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.19"^^xsd:string) "N(omega)-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.19"^^xsd:string) "omega-protein-N-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.19"^^xsd:string) "ADP-ribose-L-arginine cleaving enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.19"^^xsd:string) "Catalysis of the reaction: N2-(ADP-D-ribosyl)-L-arginine + H2O = L-arginine + ADP-ribose."^^xsd:string) AnnotationAssertion( "ADPribosylarginine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.19"^^xsd:string) "protein ADP-ribosylarginine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.19"^^xsd:string) "protein-nomega-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.19"^^xsd:string) "ADP-ribose-L-arginine cleavage enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "ADP-ribosylarginine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.6"^^xsd:string) "adenylate aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.6"^^xsd:string) "adenylate desaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.6"^^xsd:string) "Catalysis of the reaction: AMP + H2O = IMP + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.6"^^xsd:string) "myoadenylate deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.6"^^xsd:string) "adenosine 5-phosphate aminohydrolase activity"^^xsd:string) AnnotationAssertion( "adenylate deaminase reaction"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.6"^^xsd:string) "AMP aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.6"^^xsd:string) "5-adenylic acid deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.6"^^xsd:string) "AMP aminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.6"^^xsd:string) "adenylic acid deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.6"^^xsd:string) "adenylate deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.6"^^xsd:string) "adenyl deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.6"^^xsd:string) "adenylic deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.6"^^xsd:string) "5-AMP deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.6"^^xsd:string) "5-adenylate deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.6"^^xsd:string) "adenosine 5-monophosphate deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.6"^^xsd:string) "adenosine monophosphate deaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "AMP deaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.53"^^xsd:string) "diadenosine 5',5'''-P(1),P(4)-tetraphosphate phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.53"^^xsd:string) "AP-4-A phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.53"^^xsd:string) "Catalysis of the reaction: ADP + ATP = phosphate + P(1),P(4)-bis(5'-adenosyl)tetraphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.53"^^xsd:string) "adenine triphosphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion( "ADP:ATP adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.53"^^xsd:string) "diadenosinetetraphosphate alpha-beta-phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.53"^^xsd:string) "diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.53"^^xsd:string) "bis(5'-nucleosyl)-tetraphosphate phosphorylase (NDP-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "ATP adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.53"^^xsd:string) "dinucleoside oligophosphate alphabeta-phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.53"^^xsd:string) "diadenosine 5',5'''-P1,P4-tetraphosphate alphabeta-phosphorylase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.53"^^xsd:string) "diadenosinetetraphosphate alphabeta-phosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ATP citrate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.8"^^xsd:string) "acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.8"^^xsd:string) "ATP-citrate (pro-S-)-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.8"^^xsd:string) "ATP-citric lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.8"^^xsd:string) "ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.8"^^xsd:string) "acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.8"^^xsd:string) "adenosine triphosphate citrate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.8"^^xsd:string) "acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.8"^^xsd:string) "ATP citrate (pro-S)-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.8"^^xsd:string) Annotation( "RHEA:21163"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + ADP + H(+) + oxaloacetate + phosphate = ATP + citrate + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.8"^^xsd:string) "citrate cleavage enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.8"^^xsd:string) "ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)"^^xsd:string) AnnotationAssertion( "ATP-citrate (pro-S)-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.8"^^xsd:string) "citric cleavage enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.8"^^xsd:string) "citrate-ATP lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.17"^^xsd:string) "phosphoribosyl ATP synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.17"^^xsd:string) "phosphoribosyladenosine triphosphate:pyrophosphate phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.17"^^xsd:string) "phosphoribosyl ATP:pyrophosphate phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.17"^^xsd:string) "phosphoribosyladenosine triphosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.17"^^xsd:string) "Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.17"^^xsd:string) "adenosine triphosphate phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ATP phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.17"^^xsd:string) "phosphoribosyl-ATP pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.17"^^xsd:string) "phosphoribosyl-ATP:pyrophosphate-phosphoribosyl phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.17"^^xsd:string) "1-(5-phospho-D-ribosyl)-ATP:diphosphate phospho-alpha-D-ribosyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.17"^^xsd:string) "phosphoribosyl-ATP diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.17"^^xsd:string) "phosphoribosyladenosine triphosphate pyrophosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:8428937"^^xsd:string) "Catalysis of the transfer of a methyl group to the oxygen atom of a carboxyl group at the C-terminal of a protein."^^xsd:string) AnnotationAssertion( "C-terminal protein carboxyl methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein C-terminal carboxyl O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.11"^^xsd:string) "CDP-DG:inositol transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.11"^^xsd:string) "cytidine diphosphoglyceride-inositol transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.11"^^xsd:string) "CDP diglyceride-inositol phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion( "phosphatidylinositol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.11"^^xsd:string) "CDP-diacylglycerol--inositol phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.11"^^xsd:string) "cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:myo-inositol 3-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.11"^^xsd:string) "CDP-diacylglycerol:myo-inositol-3-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.11"^^xsd:string) Annotation( "RHEA:11583"^^xsd:string) "Catalysis of the reaction: myo-inositol + CDP-diacylglycerol = 1-phosphatidyl-1D-myo-inositol + CMP + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.11"^^xsd:string) "CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.11"^^xsd:string) "CDPdiacylglycerol-inositol 3-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.11"^^xsd:string) "cytidine diphosphodiglyceride-inositol phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.11"^^xsd:string) "CDP-diglyceride-inositol transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.11"^^xsd:string) "CDP-diglyceride:inositol transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.11"^^xsd:string) "cytidine diphosphoglyceride-inositol phosphatidyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.8"^^xsd:string) "CDP-diglyceride-L-serine phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion( "serine exchange enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.8"^^xsd:string) "CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.8"^^xsd:string) "CDP-diglycerine-serine O-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.8"^^xsd:string) "CDPdiglyceride-serine O-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.8"^^xsd:string) "cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "CDP-diacylglycerol-serine O-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.8"^^xsd:string) "PS synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.8"^^xsd:string) "CDPdiacylglycerol-serine O-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.8"^^xsd:string) "CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.8"^^xsd:string) "cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.8"^^xsd:string) "phosphatidylserine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.8"^^xsd:string) "phosphatidylserine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.8"^^xsd:string) "cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.8"^^xsd:string) "Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.8"^^xsd:string) "CDP-diglyceride:serine phosphatidyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.4.2"^^xsd:string) "cytidine triphosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.2"^^xsd:string) "UTP--ammonia ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.2"^^xsd:string) "uridine triphosphate aminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "CTP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.2"^^xsd:string) "cytidine 5'-triphosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.2"^^xsd:string) "CTP synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.2"^^xsd:string) "UTP:ammonia ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.2"^^xsd:string) "Catalysis of the reaction: ATP + UTP + NH3 = ADP + phosphate + CTP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-amino-acid oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.3"^^xsd:string) "L-amino acid:O2 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.3"^^xsd:string) "D-amino-acid:oxygen oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.3"^^xsd:string) "new yellow enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.3"^^xsd:string) "Catalysis of the reaction: a D-amino acid + H2O + O2 = a 2-oxo acid + NH3 + hydrogen peroxide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-arabinono-1,4-lactone oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.37"^^xsd:string) Annotation( "RHEA:23759"^^xsd:string) "Catalysis of the reaction: D-arabinono-1,4-lactone + O(2) = dehydro-D-arabinono-1,4-lactone + H(2)O(2) + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.37"^^xsd:string) "D-arabinono-1,4-lactone:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "DNA 5-cytosine methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "deoxyribonucleic (cytosine-5-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "deoxyribonucleic methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "methylphosphotriester-DNA methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "modification methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "cytosine DNA methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "restriction-modification system activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "DNA-cytosine 5-methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "cytosine 5-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "DNA cytosine C5 methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "site-specific DNA-methyltransferase (cytosine-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "deoxyribonucleic acid (cytosine-5-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "DNA (cytosine-5-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "type II DNA methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "DNA cytosine methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "DNA cytosine C(5) methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "cytosine-specific DNA methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "cytosine DNA methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "DNA-cytosine methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "DNA polymerase gamma"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "Taq DNA polymerase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "Tca DNA polymerase"^^xsd:string) AnnotationAssertion( "DNA polymerase V activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "sequenase"^^xsd:string) AnnotationAssertion( "epsilon DNA polymerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "DNA-directed DNA polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "deoxyribonucleic duplicase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "deoxyribonucleic polymerase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "deoxyribonucleic acid duplicase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and primer."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "DNA-dependent DNA polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "DNA replicase activity"^^xsd:string) AnnotationAssertion( "theta DNA polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "duplicase"^^xsd:string) AnnotationAssertion( "beta DNA polymerase activity"^^xsd:string) AnnotationAssertion( "mu DNA polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "DNA polymerase beta"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "DNA polymerase III"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "DNA polymerase alpha"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "DNA duplicase activity"^^xsd:string) AnnotationAssertion( "iota DNA polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity"^^xsd:string) AnnotationAssertion( "eta DNA polymerase activity"^^xsd:string) AnnotationAssertion( "delta DNA polymerase activity"^^xsd:string) AnnotationAssertion( "kappa DNA polymerase activity"^^xsd:string) AnnotationAssertion( "alpha DNA polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "Klenow fragment"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "DNA nucleotidyltransferase (DNA-directed) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "DNA polymerase I"^^xsd:string) AnnotationAssertion( "nu DNA polymerase activity"^^xsd:string) AnnotationAssertion( "sigma DNA polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "DNA polymerase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "Taq Pol I"^^xsd:string) AnnotationAssertion( "gamma DNA-directed DNA polymerase activity"^^xsd:string) AnnotationAssertion( "zeta DNA polymerase activity"^^xsd:string) AnnotationAssertion( "lambda DNA polymerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA primase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0716720094"^^xsd:string) "Catalysis of the synthesis of a short RNA primer on a DNA template, providing a free 3'-OH that can be extended by DNA-directed DNA polymerases. Catalyzed by a DNA-directed RNA polymerase that forms a complex with alpha DNA polymerase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "RNA nucleotidyltransferase (DNA-directed) activity"^^xsd:string) AnnotationAssertion( "DNA-directed RNA polymerase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "transcriptase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "RNA polymerase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "C RNA formation factors"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "DNA-dependent RNA nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion( "DNA-directed RNA polymerase III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "RNA polymerase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "RNA polymerase III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "C ribonucleic acid formation factors"^^xsd:string) AnnotationAssertion( "DNA-directed RNA polymerase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "DNA-dependent ribonucleate nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "DNA-directed RNA polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "DNA-dependent RNA polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "deoxyribonucleic acid-dependent ribonucleic acid polymerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.99.3"^^xsd:string) "deoxyribonucleic photolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.3"^^xsd:string) "photolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.3"^^xsd:string) "DNA cyclobutane dipyrimidine photolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.3"^^xsd:string) "Catalysis of the reaction: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA). This reaction represents the reactivation of irradiated DNA by light."^^xsd:string) AnnotationAssertion(Annotation( "PMID:16302973"^^xsd:string) "CPD photolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.3"^^xsd:string) "DNA-photoreactivating enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.3"^^xsd:string) "deoxyribocyclobutadipyrimidine pyrimidine-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.3"^^xsd:string) "deoxyribonucleic cyclobutane dipyrimidine photolyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "deoxyribodipyrimidine photo-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.3"^^xsd:string) "phr A photolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.3"^^xsd:string) "deoxyribonucleate pyrimidine dimer lyase (photosensitive)"^^xsd:string) AnnotationAssertion( "deoxyribodipyrimidine photolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.3"^^xsd:string) "photoreactivating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.3"^^xsd:string) "PRE"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.3"^^xsd:string) "PhrB photolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.3"^^xsd:string) "dipyrimidine photolyase (photosensitive)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.21"^^xsd:string) "DNA glycosidase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.21"^^xsd:string) "deoxyribonucleate 3-methyladenine glycosidase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.21"^^xsd:string) "DNA-3-methyladenine glycosylase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.21"^^xsd:string) Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:10872450"^^xsd:string) Annotation( "PMID:9224623"^^xsd:string) "Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site."^^xsd:string) AnnotationAssertion( "DNA-3-methyladenine glycosidase II activity"^^xsd:string) AnnotationAssertion(rdfs:label "alkylbase DNA N-glycosylase activity"^^xsd:string) AnnotationAssertion( "alkylbase DNA glycosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.21"^^xsd:string) "AlkA"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.21"^^xsd:string) "alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.21"^^xsd:string) "3-methyladenine DNA glycosylase II"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.99.18"^^xsd:string) "Phage-T(4) UV endonuclease activity"^^xsd:string) AnnotationAssertion(rdfs:label "DNA-(apurinic or apyrimidinic site) lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.18"^^xsd:string) "phage-T4 UV endonuclease"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.18"^^xsd:string) "E. coli endonuclease III activity"^^xsd:string) AnnotationAssertion( "endonuclease VIII activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.18"^^xsd:string) "deoxyribonuclease (apurinic or apyrimidinic) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.18"^^xsd:string) "micrococcus luteus UV endonuclease"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.18"^^xsd:string) "Catalysis of the cleavage of the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.18"^^xsd:string) "Phage-T4 UV endonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.18"^^xsd:string) "AP site-DNA 5'-phosphomonoester-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.18"^^xsd:string) "endodeoxyribonuclease (apurinic or apyrimidinic) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.18"^^xsd:string) "Micrococcus luteus UV endonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.18"^^xsd:string) "AP lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.18"^^xsd:string) "X-ray endonuclease III"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.18"^^xsd:string) "DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.18"^^xsd:string) "AP endonuclease class I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.18"^^xsd:string) "E. coli endonuclease III"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.63"^^xsd:string) "DNA-6-O-methylguanine:protein-L-cysteine S-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methylated-DNA-[protein]-cysteine S-methyltransferase activity"^^xsd:string) AnnotationAssertion( "DNA-6-O-methylguanine:[protein]-L-cysteine S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.63"^^xsd:string) "Catalysis of the reaction: DNA (containing 6-O-methylguanine) + (protein)-L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.63"^^xsd:string) "O-6-methylguanine-DNA-alkyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.63"^^xsd:string) "6-O-methylguanine-DNA methyltransferase activity"^^xsd:string) AnnotationAssertion( "O6-alkylguanine-DNA alkyltransferase"^^xsd:string) AnnotationAssertion( "MGMT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.63"^^xsd:string) "methylated-DNA-protein-cysteine S-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0716720094"^^xsd:string) "Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+."^^xsd:string) AnnotationAssertion(rdfs:label "DNA ligase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.5.1.1"^^xsd:string) "sealase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.1"^^xsd:string) "DNA repair enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "DNA ligase (ATP) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.1"^^xsd:string) "DNA-joining enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.1"^^xsd:string) "polydeoxyribonucleotide synthase (ATP) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.1"^^xsd:string) "deoxyribonucleic repair enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.1"^^xsd:string) "deoxyribonucleic ligase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.1"^^xsd:string) "deoxyribonucleic acid-joining enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.1"^^xsd:string) "polynucleotide ligase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.1"^^xsd:string) "DNA joinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.1"^^xsd:string) "deoxyribonucleic-joining enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.1"^^xsd:string) "deoxyribonucleic acid ligase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.1"^^xsd:string) "deoxyribonucleic acid joinase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.1"^^xsd:string) "polynucleotide ligase (ATP) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.1"^^xsd:string) "Catalysis of the reaction: ATP + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + diphosphate + deoxyribonucleotide(n+m)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.1"^^xsd:string) "deoxyribonucleate ligase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.1"^^xsd:string) "deoxyribonucleic joinase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.1"^^xsd:string) "deoxyribonucleic acid repair enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.1"^^xsd:string) "poly(deoxyribonucleotide):poly(deoxyribonucleotide) ligase (AMP-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "Polydeoxyribonucleotide synthase (NAD(+)) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "polydeoxyribonucleotide synthase (NAD)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "polynucleotide ligase (nicotinamide adenine dinucleotide)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "polynucleotide synthetase (nicotinamide adenine dinucleotide)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "deoxyribonucleic ligase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "deoxyribonucleic-joining enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "DNA ligase (NAD)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "polydeoxyribonucleotide synthase (NAD+) activity"^^xsd:string) AnnotationAssertion(rdfs:label "DNA ligase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "polynucleotide ligase (NAD(+)) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "polynucleotide ligase (NAD)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "DNA repair enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "poly(deoxyribonucleotide):poly(deoxyribonucleotide) ligase (AMP-forming, NMN-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "DNA-joining enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "polynucleotide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "deoxyribonucleate ligase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "deoxyribonucleic acid ligase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "deoxyribonucleic joinase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "deoxyribonucleic repair enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "deoxyribonucleic acid joinase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "polynucleotide ligase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "DNA joinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "Catalysis of the reaction: NAD+ + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + nicotinamide nucleotide + deoxyribonucleotide(n+m)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.2"^^xsd:string) "polynucleotide ligase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.31"^^xsd:string) "terminal addition enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.31"^^xsd:string) "terminal deoxyribonucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.31"^^xsd:string) "addase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.31"^^xsd:string) "deoxynucleotidyl terminal transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.31"^^xsd:string) "deoxyribonucleic nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "DNA nucleotidylexotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.31"^^xsd:string) "terminal deoxynucleotide transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.31"^^xsd:string) "TdT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.31"^^xsd:string) "terminal transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.31"^^xsd:string) "terminal deoxynucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.31"^^xsd:string) "nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.31"^^xsd:string) "Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.31"^^xsd:string) "deoxyribonucleic acid nucleotidyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA photolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:11124949"^^xsd:string) "Catalysis of the repair of a photoproduct resulting from ultraviolet irradiation of two adjacent pyrimidine residues in DNA."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA (6-4) photolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:11124949"^^xsd:string) "Catalysis of the reaction: pyrimidine-pyrimidone (6-4) photoproduct (in DNA) = 2 pyrimidine residues (in DNA). Catalyzes the reactivation of ultraviolet-irradiated DNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:8811192"^^xsd:string) "Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA."^^xsd:string) AnnotationAssertion(rdfs:label "DNA topoisomerase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.99.1.2"^^xsd:string) "omega-protein activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.99.1.2"^^xsd:string) "untwisting enzyme activity"^^xsd:string) AnnotationAssertion( "type I DNA topoisomerase activity"^^xsd:string) AnnotationAssertion( "type I topoisomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "DNA topoisomerase type I activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8811192"^^xsd:string) "Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.99.1.2"^^xsd:string) "relaxing enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.99.1.2"^^xsd:string) "topoisomerase"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.99.1.2"^^xsd:string) "nicking-closing enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.99.1.2"^^xsd:string) "deoxyribonucleate topoisomerase"^^xsd:string) AnnotationAssertion( "DNA topoisomerase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.99.1.2"^^xsd:string) "swivelase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.99.1.3"^^xsd:string) "type II DNA topoisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.99.1.3"^^xsd:string) "DNA topoisomerase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.99.1.3"^^xsd:string) "topoisomerase"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8811192"^^xsd:string) "Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.99.1.3"^^xsd:string) "deoxyribonucleate topoisomerase"^^xsd:string) AnnotationAssertion( "topoisomerase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.99.1.3"^^xsd:string) "DNA-gyrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.99.1.3"^^xsd:string) "DNA topoisomerase (ATP-hydrolysing)"^^xsd:string) AnnotationAssertion(rdfs:label "DNA topoisomerase type II (ATP-hydrolyzing) activity"^^xsd:string) AnnotationAssertion( "DNA topoisomerase type II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.99.1.3"^^xsd:string) "deoxyribonucleic topoisomerase activity"^^xsd:string) AnnotationAssertion( "DNA gyrase activity"^^xsd:string) AnnotationAssertion( "DNA topoisomerase IV activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.2"^^xsd:string) "flavin adenine dinucleotide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.2"^^xsd:string) "FAD synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.2"^^xsd:string) "adenosine triphosphate-riboflavin mononucleotide transadenylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.2"^^xsd:string) "FAD pyrophosphorylase activity"^^xsd:string) AnnotationAssertion( "ATP:FMN adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.2"^^xsd:string) Annotation( "RHEA:17240"^^xsd:string) "Catalysis of the reaction: ATP + FMN = diphosphate + FAD."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.2"^^xsd:string) "adenosine triphosphate-riboflavine mononucleotide transadenylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.2"^^xsd:string) "riboflavine adenine dinucleotide adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.2"^^xsd:string) "riboflavin mononucleotide adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.2"^^xsd:string) "FAD diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.2"^^xsd:string) "riboflavin adenine dinucleotide pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "FMN adenylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.1.7"^^xsd:string) Annotation( "RHEA:17188"^^xsd:string) "Catalysis of the reaction: IMP + NADP(+) + NH(4)(+) = GMP + 2 H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.7"^^xsd:string) "inosine-5'-phosphate:NADP+ oxidoreductase (aminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.7"^^xsd:string) "guanosine 5'-monophosphate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.7"^^xsd:string) "NADPH:GMP oxidoreductase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.7"^^xsd:string) "guanosine 5'-phosphate reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "GMP reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.7"^^xsd:string) "guanylate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.7"^^xsd:string) "guanosine 5'-monophosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.7"^^xsd:string) "NADPH2:guanosine-5'-phosphate oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.7"^^xsd:string) "NADPH:guanosine-5'-phosphate oxidoreductase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.7"^^xsd:string) "guanosine monophosphate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.4.1"^^xsd:string) "guanylate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.1"^^xsd:string) "xanthosine 5'-monophosphate aminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.1"^^xsd:string) "Xanthosine-5'-phosphate--ammonia ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.1"^^xsd:string) "xanthosine-5'-phosphate-ammonia ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "GMP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.1"^^xsd:string) "xanthosine-5'-phosphate:ammonia ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.1"^^xsd:string) "XMP aminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.1"^^xsd:string) "Catalysis of the reaction: ATP + xanthosine 5'-phosphate + NH3 = AMP + diphosphate + GMP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.5.2"^^xsd:string) "Catalysis of the reaction: ATP + xanthosine 5'-phosphate + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.2"^^xsd:string) "GMP synthase (glutamine-hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.2"^^xsd:string) "guanylate synthetase (glutamine-hydrolyzing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.2"^^xsd:string) "guanosine 5'-monophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.2"^^xsd:string) "guanosine monophosphate synthetase (glutamine-hydrolyzing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.2"^^xsd:string) "xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.2"^^xsd:string) "glutamine amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.2"^^xsd:string) "GMP synthetase (glutamine-hydrolyzing) activity"^^xsd:string) AnnotationAssertion(rdfs:label "GMP synthase (glutamine-hydrolyzing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.2"^^xsd:string) "xanthosine 5'-phosphate amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.2"^^xsd:string) "GMP synthetase (glutamine-hydrolysing)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GPI-anchor transamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0471331309"^^xsd:string) "Catalysis of the formation of the linkage between a protein and a glycosylphosphatidylinositol anchor. The reaction probably occurs by subjecting a peptide bond to nucleophilic attack by the amino group of ethanolamine-GPI, transferring the protein from a signal peptide to the GPI anchor."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "heterotrimeric G-protein GTPase, gamma-subunit"^^xsd:string) AnnotationAssertion( "protein-synthesizing GTPase activity, termination"^^xsd:string) AnnotationAssertion( "dynamin GTPase activity"^^xsd:string) AnnotationAssertion( "tubulin GTPase activity"^^xsd:string) AnnotationAssertion( "hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement"^^xsd:string) AnnotationAssertion( "Ran small monomeric GTPase activity"^^xsd:string) AnnotationAssertion( "small monomeric GTPase activity"^^xsd:string) AnnotationAssertion( "protein-synthesizing GTPase activity, initiation"^^xsd:string) AnnotationAssertion( "Sar small monomeric GTPase activity"^^xsd:string) AnnotationAssertion( "heterotrimeric G-protein GTPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "GTPase activity"^^xsd:string) AnnotationAssertion( "signal-recognition-particle GTPase activity"^^xsd:string) AnnotationAssertion( "RHEB small monomeric GTPase activity"^^xsd:string) AnnotationAssertion( "heterotrimeric G-protein GTPase, beta-subunit"^^xsd:string) AnnotationAssertion( "protein-synthesizing GTPase activity, elongation"^^xsd:string) AnnotationAssertion( "heterotrimeric G-protein GTPase, alpha-subunit"^^xsd:string) AnnotationAssertion( "Rho small monomeric GTPase activity"^^xsd:string) AnnotationAssertion( "Rab small monomeric GTPase activity"^^xsd:string) AnnotationAssertion( "ARF small monomeric GTPase activity"^^xsd:string) AnnotationAssertion( "Ras small monomeric GTPase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the reaction: GTP + H2O = GDP + phosphate."^^xsd:string) AnnotationAssertion( "protein-synthesizing GTPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GTP cyclohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.16"^^xsd:string) Annotation( "EC:3.5.4.25"^^xsd:string) Annotation( "EC:3.5.4.29"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.16"^^xsd:string) "GTP 8-formylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.16"^^xsd:string) "Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "GTP cyclohydrolase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.16"^^xsd:string) "guanosine triphosphate 8-deformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.16"^^xsd:string) "GTP 7,8-8,9-dihydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.16"^^xsd:string) "guanosine triphosphate cyclohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.16"^^xsd:string) "dihydroneopterin triphosphate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GTP cyclohydrolase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.25"^^xsd:string) "guanosine triphosphate cyclohydrolase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.25"^^xsd:string) "GTP-8-formylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.25"^^xsd:string) "GTP 7,8-8,9-dihydrolase (diphosphate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.25"^^xsd:string) Annotation( "RHEA:23707"^^xsd:string) "Catalysis of the reaction: GTP + 3 H(2)O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + diphosphate + formate + 3 H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.10"^^xsd:string) "inosinicase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.10"^^xsd:string) "Catalysis of the reaction: IMP + H2O = 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.10"^^xsd:string) "inosinate cyclohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.10"^^xsd:string) "IMP 1,2-hydrolase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.10"^^xsd:string) "IMP synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "IMP cyclohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "IMP dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.205"^^xsd:string) "inosinate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.205"^^xsd:string) "IMP oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.205"^^xsd:string) "inosine-5'-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.205"^^xsd:string) "inosine monophosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.205"^^xsd:string) "inosine 5'-monophosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.205"^^xsd:string) "Catalysis of the reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.205"^^xsd:string) "IMP:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.205"^^xsd:string) "inosine monophosphate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.205"^^xsd:string) "inosinic acid dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.14"^^xsd:string) "sorbitol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.14"^^xsd:string) "NAD-sorbitol dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.14"^^xsd:string) "Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.14"^^xsd:string) "polyol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.14"^^xsd:string) "glucitol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.14"^^xsd:string) "NAD-dependent sorbitol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.14"^^xsd:string) "L-iditol:NAD+ 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.14"^^xsd:string) "L-iditol:NAD oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.14"^^xsd:string) "L-iditol (sorbitol) dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-iditol 2-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.14"^^xsd:string) "NAD+-dependent sorbitol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-iduronidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.76"^^xsd:string) "Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.76"^^xsd:string) "alpha-L-iduronidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.76"^^xsd:string) "glycosaminoglycan alpha-L-iduronohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-hydroxyaminoacid dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.17"^^xsd:string) "serine deaminase activity"^^xsd:string) AnnotationAssertion( "L-serine hydro-lyase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.17"^^xsd:string) "L-serine ammonia-lyase (pyruvate-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-serine ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.17"^^xsd:string) "L-serine dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.17"^^xsd:string) "Catalysis of the reaction: L-serine = pyruvate + NH3."^^xsd:string) AnnotationAssertion( "L-serine deaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.38"^^xsd:string) "reductase, acetyl-gamma-glutamyl phosphate"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.38"^^xsd:string) "N-acetyl-L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetyl-gamma-glutamyl-phosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.38"^^xsd:string) "N-acetylglutamate 5-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.38"^^xsd:string) "N-acetyl-L-glutamate gamma-semialdehyde:NADP oxidoreductase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.38"^^xsd:string) "Catalysis of the reaction: N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.38"^^xsd:string) "N-acetylglutamic gamma-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.38"^^xsd:string) "NAGSA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.38"^^xsd:string) "N-acetyl-glutamate semialdehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.6.12"^^xsd:string) "N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.12"^^xsd:string) "acetylgalactosamine 4-sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.12"^^xsd:string) "Catalysis of the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate."^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylgalactosamine-4-sulfatase activity"^^xsd:string) AnnotationAssertion( "N-acetylgalactosamine-4-sulphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.12"^^xsd:string) "N-acetylgalactosamine 4-sulfate sulfohydrolase activity"^^xsd:string) AnnotationAssertion( "arylsulfatase B"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.12"^^xsd:string) "chondroitinsulfatase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.45"^^xsd:string) "2-acetamido-2-deoxy-alpha-D-glucose 1-phosphodiester acetamidodeoxyglucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.45"^^xsd:string) "alpha-N-acetyl-D-glucosamine-1-phosphodiester N-acetylglucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.45"^^xsd:string) "phosphodiester glycosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.45"^^xsd:string) "Catalysis of the reaction: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O = N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.45"^^xsd:string) "lysosomal alpha-N-acetylglucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.45"^^xsd:string) "alpha-N-acetylglucosaminyl phosphodiesterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.45"^^xsd:string) "glycoprotein-N-acetyl-D-glucosaminyl-phospho-D-mannose N-acetyl-D-glucosaminylphosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "beta-1,4-GalT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "UDP-galactose-N-acetylglucosamine beta-1,4-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "UDP-galactose-N-acetylglucosamine galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "N-acetylglucosamine (beta-1,4)galactosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetyllactosamine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "Gal-T"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "UDP-galactose-acetylglucosamine galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "N-acetyllactosamine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "NAL synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "lactosamine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "UDPgalactose:N-acetylglucosaminyl(beta-1,4)galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "UDP-galactose-N-acetylglucosamine beta-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "UDPgalactose:N-acetyl-D-glucosamine 4-beta-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "N-acetylglucosamine beta-(1,4)-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "lactose synthetase A protein"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "acetyllactosamine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "UDP-beta-1,4-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "UDP-Gal:N-acetylglucosamine beta-1,4-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "lactosamine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "UDPgalactose-N-acetylglucosamine beta-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "beta-1,4-galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "UDP-galactose:N-acetyl-D-glucosamine 4-beta-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "UDP-galactose N-acetylglucosamine beta-4-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "beta-(1,4)-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "Catalysis of the reaction: UDP-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "UDP-galactose:N-acetylglucosaminide beta-1,4-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "uridine diphosphogalactose-acetylglucosamine galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.90"^^xsd:string) "beta-N-acetylglucosaminide beta-1,4-galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.92"^^xsd:string) "ganglioside GM2 synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.92"^^xsd:string) "uridine diphosphoacetylgalactosamine-ganglioside GM3 acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.92"^^xsd:string) "UDP acetylgalactosamine-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.92"^^xsd:string) "UDP-N-acetylgalactosamine GM3 N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.92"^^xsd:string) "ganglioside GM3 acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.92"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + (N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide = UDP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.92"^^xsd:string) "GalNAc-T activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.92"^^xsd:string) "UDP-N-acetyl-D-galactosamine:1-O-[O-(N-acetyl-alpha-neuraminosyl)-(2->3)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]-ceramide 1,4-beta-N-acetyl-D-galactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.92"^^xsd:string) "GM2/GD2-synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.92"^^xsd:string) "asialo-GM2 synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.92"^^xsd:string) "UDP-N-acetyl-D-galactosamine:(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetyl-D-galactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.92"^^xsd:string) "uridine diphosphoacetylgalactosamine-hematoside acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.92"^^xsd:string) "uridine diphosphoacetylgalactosamine-acetylneuraminylgalactosylglucosylceramide acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.92"^^xsd:string) "beta-1,4N-aetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.92"^^xsd:string) "GM2 synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.26"^^xsd:string) "aspartylglucosylamine deaspartylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.26"^^xsd:string) "aspartylglucosylaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.26"^^xsd:string) "4-N-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.26"^^xsd:string) "aspartylglycosylamine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.26"^^xsd:string) "N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.26"^^xsd:string) "N-aspartyl-beta-glucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.26"^^xsd:string) "aspartylglucosylaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.26"^^xsd:string) "glucosylamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.26"^^xsd:string) "beta-aspartylglucosylamine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.26"^^xsd:string) "glycosylasparaginase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.26"^^xsd:string) Annotation( "RHEA:11547"^^xsd:string) "Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H(2)O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.26"^^xsd:string) "aspartylglucosaminidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.1.16"^^xsd:string) "1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.16"^^xsd:string) "1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide ketol-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.16"^^xsd:string) "N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.16"^^xsd:string) Annotation( "RHEA:15472"^^xsd:string) "Catalysis of the reaction: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.16"^^xsd:string) "phosphoribosylformiminoaminophosphoribosylimidazolecarboxamide isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.16"^^xsd:string) "phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.16"^^xsd:string) "N-(phosphoribosylformimino) aminophosphoribosylimidazolecarboxamide isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.30"^^xsd:string) "poly(ADP-ribose) synthase activity"^^xsd:string) AnnotationAssertion( "NAD ADP-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.30"^^xsd:string) "poly(ADP-ribose)polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.30"^^xsd:string) "Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.30"^^xsd:string) "NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.30"^^xsd:string) "ADP-ribosyltransferase (polymerizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.30"^^xsd:string) "poly(ADP-ribose) synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.30"^^xsd:string) "poly(adenosine diphosphate ribose) polymerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "NAD+ ADP-ribosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.23"^^xsd:string) "DPN kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "NAD+ kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.23"^^xsd:string) Annotation( "RHEA:18632"^^xsd:string) "Catalysis of the reaction: ATP + NAD(+) = ADP + 2 H(+) + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.23"^^xsd:string) "nicotinamide adenine dinucleotide kinase activity"^^xsd:string) AnnotationAssertion( "NAD kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.23"^^xsd:string) "ATP:NAD+ 2'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.23"^^xsd:string) "NADK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.23"^^xsd:string) "nicotinamide adenine dinucleotide kinase (phosphorylating)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.5.1"^^xsd:string) "NAD synthetase (glutamine-hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.1"^^xsd:string) "DPN synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.1"^^xsd:string) "desamidonicotinamide adenine dinucleotide amidotransferase activity"^^xsd:string) AnnotationAssertion( "NAD synthase (glutamine-hydrolyzing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.1"^^xsd:string) "NAD+ synthetase (glutamine-hydrolyzing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.1"^^xsd:string) "nicotinamide adenine dinucleotide synthetase (glutamine) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.1"^^xsd:string) "NAD+ synthase (glutamine-hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.1"^^xsd:string) "NAD(+) synthetase (glutamine-hydrolyzing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.1"^^xsd:string) "deamido-NAD+:L-glutamine amido-ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.1"^^xsd:string) "Catalysis of the reaction: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate."^^xsd:string) AnnotationAssertion(rdfs:label "NAD+ synthase (glutamine-hydrolyzing) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.5"^^xsd:string) "Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose."^^xsd:string) AnnotationAssertion(rdfs:label "NAD+ nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.5"^^xsd:string) "NAD hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.5"^^xsd:string) "nicotinamide adenine dinucleotide nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.5"^^xsd:string) "DPN hydrolase activity"^^xsd:string) AnnotationAssertion( "NAD nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.5"^^xsd:string) "nicotinamide adenine dinucleotide glycohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.5"^^xsd:string) "NADase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.5"^^xsd:string) "ADP-ribosyl cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.5"^^xsd:string) "NAD glycohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.5"^^xsd:string) "NAD+ glycohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.5"^^xsd:string) "diphosphopyridine nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.5"^^xsd:string) "DPNase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "NADH:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "beta-NADH dehydrogenase dinucleotide activity"^^xsd:string) AnnotationAssertion(rdfs:label "NADH dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "diphosphopyrinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "NADH2 dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "reduced diphosphopyridine nucleotide diaphorase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "NADH hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "diaphorase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "dihydrocodehydrogenase I dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "NADH:cytochrome c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "NADH:(acceptor) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "NADH diaphorase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "dihydronicotinamide adenine dinucleotide dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "type I dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "DPNH diaphorase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "type 1 dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "NADH oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "NADH-menadione oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.3"^^xsd:string) "diphosphopyridine diaphorase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "azoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "p-benzoquinone reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "NAD(P)H dehydrogenase (quinone) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "QR1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "NADH-menadione reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "naphthoquinone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "vitamin-K reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "menadione oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "NAD(P)H:(quinone-acceptor)oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "quinone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "flavoprotein NAD(P)H-quinone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "vitamin K reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "phylloquinone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "NAD(P)H-quinone dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "viologen accepting pyridine nucleotide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "NAD(P)H-quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "diaphorase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "NQO1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "NAD(P)H menadione reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "reduced NAD(P)H dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "NAD(P)H:quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "NAD(P)H2 dehydrogenase (quinone)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "NAD(P)H: menadione oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "NAD(P)H dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "DT-diaphorase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "Naphthoquinone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "NAD(P)H(2) dehydrogenase (quinone) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.2"^^xsd:string) "menadione reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "NAD(P)+-arginine ADP-ribosyltransferase activity"^^xsd:string) AnnotationAssertion( "NAD(P)-arginine ADP-ribosyltransferase activity"^^xsd:string) AnnotationAssertion( "peptidyl-arginine ADP-ribosylation activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.31"^^xsd:string) "NAD(P)+:protein-L-arginine ADP-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.31"^^xsd:string) "mono(ADPribosyl)transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "NAD(P)+-protein-arginine ADP-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.31"^^xsd:string) "NAD+:L-arginine ADP-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.31"^^xsd:string) "NAD(P)(+)--arginine ADP-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.31"^^xsd:string) "mono(ADP-ribosyl)transferase activity"^^xsd:string) AnnotationAssertion( "protein-arginine ADP-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.31"^^xsd:string) "ADP-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.31"^^xsd:string) "Catalysis of the reaction: NAD(P)+ + L-arginine = nicotinamide + N2-(ADP-D-ribosyl)-L-arginine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.31"^^xsd:string) "NAD(+):L-arginine ADP-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.31"^^xsd:string) "NAD(P)+:L-arginine ADP-D-ribosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NAD(P)+ transhydrogenase (B-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) "NAD transhydrogenase"^^xsd:string) AnnotationAssertion( "NAD(P) transhydrogenase (B-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) "NADPH-NAD oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) "NADPH-NAD transhydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) Annotation( "MetaCyc:PYRNUTRANSHYDROGEN-RXN"^^xsd:string) Annotation( "http://pubs.acs.org/cgi-bin/abstract.cgi/jacsat/1991/113/i07/f-pdf/f_ja00007a002.pdf"^^xsd:string) "Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+, driving the transfer of a solute or solutes from one side of a membrane to the other. In the course of the reaction (left to right) one H atom is transferred from inside the cell to outside. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to both NAD+ and NADP+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) "nicotinamide nucleotide transhydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) "non-energy-linked transhydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) "nicotinamide adenine dinucleotide (phosphate) transhydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) "NADH transhydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) "pyridine nucleotide transferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) "NADPH:NAD+ transhydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) "NADH-NADP-transhydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) "pyridine nucleotide transhydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) "NADPH:NAD+ oxidoreductase (B-specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) "H+-thase"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NADPH-hemoprotein reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "NADPH:hemoprotein oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "NADPH--cytochrome P450 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "NADPH--cytochrome P450 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "FAD-cytochrome c reductase activity"^^xsd:string) AnnotationAssertion( "NADPH:cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "CPR activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "dihydroxynicotinamide adenine dinucleotide phosphate-cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "TPNH(2) cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "NADPH-cytochrome p-450 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "NADPH-dependent cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "NADPH--cytochrome c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "Catalysis of the reaction: NADPH + H+ + n oxidized hemoprotein = NADP+ + n reduced hemoprotein."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "NADP--cytochrome reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "aldehyde reductase (NADPH-dependent) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "reductase, cytochrome c (reduced nicotinamide adenine dinucleotide phosphate) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "POR"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "NADPH--ferrihemoprotein reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "TPNH2 cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "NADPH--cytochrome c reductase activity"^^xsd:string) AnnotationAssertion( "NADPH-ferrihemoprotein reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "cytochrome P-450 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "NADP--cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "TPNH-cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "NADPH:P-450 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "cytochrome c reductase (reduced nicotinamide adenine dinucleotide phosphate, NADPH, NADPH-dependent) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "ferrihemoprotein P-450 reductase activity"^^xsd:string) AnnotationAssertion( "NADPH:cytochrome P450 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "NADPH-cytochrome P-450 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "NADPH:ferrihemoprotein oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "NADPH--ferricytochrome c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "cytochrome P450 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.4"^^xsd:string) "NADPH:P450 reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.6.99.1"^^xsd:string) "TPNH-diaphorase activity"^^xsd:string) AnnotationAssertion(rdfs:label "NADPH dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.1"^^xsd:string) "NADPH diaphorase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.1"^^xsd:string) "NADPH-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.1"^^xsd:string) "NADPH2-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.1"^^xsd:string) "NADPH:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.1"^^xsd:string) "triphosphopyridine nucleotide diaphorase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.1"^^xsd:string) "dihydronicotinamide adenine dinucleotide phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.1"^^xsd:string) "TPNH dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.1"^^xsd:string) "NADPH2 diaphorase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.1"^^xsd:string) "OYE"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.1"^^xsd:string) "old yellow enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.1"^^xsd:string) "Catalysis of the reaction: NADPH + H+ + quinone acceptor = NADP+ + hydroquinone."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.1"^^xsd:string) "NADPH:(acceptor) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.1"^^xsd:string) "reduced nicotinamide adenine dinucleotide phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.1"^^xsd:string) "triphosphopyridine diaphorase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NADPH:quinone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.5"^^xsd:string) "Catalysis of the reaction: NADPH + H+ + quinone = NADP+ + semiquinone."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.5"^^xsd:string) "quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.5"^^xsd:string) "NADPH:quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.5"^^xsd:string) "zeta-crystallin activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.49"^^xsd:string) "O-acetyl-L-homoserine sulfhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.49"^^xsd:string) "OAH sulfhydrylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "L-methionine anabolism, direct, from O-acetyl-L-homoserine"^^xsd:string) AnnotationAssertion( "L-methionine biosynthetic process, direct, from O-acetyl-L-homoserine"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "L-methionine formation, direct, from O-acetyl-L-homoserine"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "L-methionine synthesis, direct, from O-acetyl-L-homoserine"^^xsd:string) AnnotationAssertion( "4.2.99.9"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.49"^^xsd:string) "Catalysis of the reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate. Also reacts with other thiols and H2S, producing homocysteine or thioethers."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.49"^^xsd:string) "O-acetylhomoserine sulfhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.49"^^xsd:string) "O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "O-acetylhomoserine aminocarboxypropyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.49"^^xsd:string) "O-acetyl-L-homoserine acetate-lyase (adding methanethiol) activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "methionine biosynthetic process, direct, from O-acetyl-L-homoserine"^^xsd:string) AnnotationAssertion( "O-acetylhomoserine (thiol)-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.48"^^xsd:string) "O-succinylhomoserine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.48"^^xsd:string) "O4-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.48"^^xsd:string) "O-succinyl-L-homoserine succinate-lyase (adding cysteine) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.48"^^xsd:string) "cystathionine synthetase activity"^^xsd:string) AnnotationAssertion( "cystathionine g-synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.48"^^xsd:string) "homoserine O-transsuccinylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.48"^^xsd:string) "O-succinylhomoserine (thiol)-lyase activity"^^xsd:string) AnnotationAssertion( "O-succinyl-L-homoserine (thiol)-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.48"^^xsd:string) "cystathionine synthase activity"^^xsd:string) AnnotationAssertion( "CTT gamma synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.48"^^xsd:string) "Catalysis of the reaction: O-succinyl-L-homoserine + L-cysteine = cystathionine + succinate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.48"^^xsd:string) "homoserine transsuccinylase activity"^^xsd:string) AnnotationAssertion( "cystathionine gamma synthase activity"^^xsd:string) AnnotationAssertion( "O-succinyl-L-homoserine succinate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.48"^^xsd:string) "O-succinylhomoserine synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cystathionine gamma-synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.5.1.4"^^xsd:string) "RNA cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.4"^^xsd:string) "RNA 3'-terminal phosphate cyclase activity"^^xsd:string) AnnotationAssertion(rdfs:label "RNA-3'-phosphate cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.4"^^xsd:string) "RNA-3'-phosphate:RNA ligase (cyclizing, AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.4"^^xsd:string) "Catalysis of the reaction: ATP + RNA 3'-terminal-phosphate = AMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.49"^^xsd:string) "RT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.49"^^xsd:string) "RNA-dependent deoxyribonucleate nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.49"^^xsd:string) "Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.49"^^xsd:string) "RNA revertase activity"^^xsd:string) AnnotationAssertion(rdfs:label "RNA-directed DNA polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.49"^^xsd:string) "reverse transcriptase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.49"^^xsd:string) "RNA-dependent DNA polymerase activity"^^xsd:string) AnnotationAssertion( "RNA-directed DNA polymerase, group II intron encoded"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.49"^^xsd:string) "deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.49"^^xsd:string) "DNA nucleotidyltransferase (RNA-directed) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.49"^^xsd:string) "RNA-instructed DNA polymerase activity"^^xsd:string) AnnotationAssertion( "RNA-directed DNA polymerase, transposon encoded"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.49"^^xsd:string) "revertase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "RNA-dependent ribonucleate nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "RNA nucleotidyltransferase (RNA-directed) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "polymerase L"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "transcriptase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "RDRP"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "ribonucleic acid-dependent ribonucleic acid polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "PB2 proteins"^^xsd:string) AnnotationAssertion(rdfs:label "RNA-directed RNA polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "ribonucleic replicase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "PB1 proteins"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "RNA-dependent RNA replicase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "Q-beta replicase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "RNA replicase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "phage f2 replicase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "RNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "RNA-dependent RNA polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "ribonucleic synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "ribonucleic acid replicase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.48"^^xsd:string) "3D polymerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA ligase (ATP) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.3"^^xsd:string) "ribonucleic ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.3"^^xsd:string) "polyribonucleotide synthase (ATP) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.3"^^xsd:string) "Catalysis of the reaction: ATP + ribonucleotide(n) + ribonucleotide(m) = AMP + diphosphate + ribonucleotide(n+m)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.3"^^xsd:string) "poly(ribonucleotide):poly(ribonucleotide) ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.5.1.3"^^xsd:string) "polyribonucleotide ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(S)-2-hydroxy-acid oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "L-2-hydroxy acid oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + hydrogen peroxide."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "(S)-2-hydroxy-acid:oxygen 2-oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "L-alpha-hydroxy acid oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "hydroxy-acid oxidase A activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "hydroxy-acid oxidase B activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "hydroxyacid oxidase A"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "oxidase, L-2-hydroxy acid"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.7"^^xsd:string) "UDP acetylglucosamine epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.7"^^xsd:string) "uridine 5'-diphospho-N-acetylglucosamine-4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.7"^^xsd:string) "uridine diphosphoacetylglucosamine epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.7"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-galactosamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.7"^^xsd:string) "uridine diphosphate N-acetylglucosamine-4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.7"^^xsd:string) "UDP-GlcNAc 4-epimerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-N-acetylglucosamine 4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.7"^^xsd:string) "UDP-N-acetyl-D-glucosamine 4-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.15"^^xsd:string) "UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.15"^^xsd:string) "UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.15"^^xsd:string) "N-acetylglucosamine-1-phosphate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.15"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.15"^^xsd:string) "GlcNAc-1-P transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.15"^^xsd:string) "dolichol phosphate N-acetylglucosamine-1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.15"^^xsd:string) "uridine diphosphoacetylglucosamine-dolichyl phosphate acetylglucosamine-1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.15"^^xsd:string) "UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.15"^^xsd:string) "UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.15"^^xsd:string) "chitobiosylpyrophosphoryldolichol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.15"^^xsd:string) "UDP-acetylglucosamine-dolichol phosphate acetylglucosamine-1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity"^^xsd:string) AnnotationAssertion( "UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosamine-1-phosphate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.15"^^xsd:string) "UDP-acetylglucosamine-dolichol phosphate acetylglucosamine phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.17"^^xsd:string) "N-acetylglucosaminyl phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.17"^^xsd:string) "UDP-N-acetyl-D-glucosamine:lysosomal-enzyme N-acetylglucosaminephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.17"^^xsd:string) "UDP-GlcNAc:glycoprotein N-acetylglucosamine-1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.17"^^xsd:string) "UDP-N-acetylglucosamine:glycoprotein N-acetylglucosamine-1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.17"^^xsd:string) "N-acetylglucosaminylphosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.17"^^xsd:string) "UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.17"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lysosomal-enzyme D-mannose = UMP + lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose."^^xsd:string) AnnotationAssertion(rdfs:label "UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.17"^^xsd:string) "lysosomal enzyme precursor acetylglucosamine-1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.17"^^xsd:string) "UDP-N-acetylglucosamine:glycoprotein N-acetylglucosaminyl-1-phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.23"^^xsd:string) "UTP:2-acetamido-2-deoxy-alpha-D-glucose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.23"^^xsd:string) "uridine diphosphate-N-acetylglucosamine pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.23"^^xsd:string) "acetylglucosamine 1-phosphate uridylyltransferase"^^xsd:string) AnnotationAssertion( "UDP-N-acetylglucosamine pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.23"^^xsd:string) "N-acetylglucosamine-1-phosphate uridyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.23"^^xsd:string) "uridine diphosphoacetylglucosamine pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.23"^^xsd:string) "UDP-acetylglucosamine pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.23"^^xsd:string) "UDP-GlcNAc pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.23"^^xsd:string) "GlmU uridylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-N-acetylglucosamine diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.23"^^xsd:string) "uridine diphosphoacetylglucosamine phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.23"^^xsd:string) Annotation( "RHEA:13512"^^xsd:string) "Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.23"^^xsd:string) "UTP:N-acetyl-alpha-D-glucosamine-1-phosphate uridylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.2"^^xsd:string) "UDP-D-galactose 4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.2"^^xsd:string) "uridine diphosphate glucose 4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.2"^^xsd:string) "UDPglucose 4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.2"^^xsd:string) "UDPG-4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.2"^^xsd:string) "UDP-glucose epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.2"^^xsd:string) "UDP-galactose 4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.2"^^xsd:string) "4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.2"^^xsd:string) "uridine diphosphate galactose 4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.2"^^xsd:string) "uridine diphosphoglucose 4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.2"^^xsd:string) "uridine diphosphoglucose epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.2"^^xsd:string) "uridine diphospho-galactose-4-epimerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-glucose 4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.2"^^xsd:string) "galactowaldenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.2"^^xsd:string) "Catalysis of the reaction: UDP-glucose = UDP-galactose."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.2"^^xsd:string) "UDPgalactose 4-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-glucose 6-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.22"^^xsd:string) Annotation( "RHEA:23599"^^xsd:string) "Catalysis of the reaction: H(2)O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:10764828"^^xsd:string) "Catalysis of the addition of UDP-glucose on to asparagine-linked (N-linked) oligosaccharides of the form Man7-9GlcNAc2 on incorrectly folded glycoproteins."^^xsd:string) AnnotationAssertion(rdfs:label "UDP-glucose:glycoprotein glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "UGGT activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UTP:glucose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.9"^^xsd:string) "uridine-diphosphate glucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.9"^^xsd:string) Annotation( "RHEA:19892"^^xsd:string) "Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.9"^^xsd:string) "glucose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.9"^^xsd:string) "UTP:alpha-D-glucose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.9"^^xsd:string) "UDP-glucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.9"^^xsd:string) "uridine diphosphoglucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.9"^^xsd:string) "UDP glucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.9"^^xsd:string) "UDPG pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.9"^^xsd:string) "UDPG phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.9"^^xsd:string) "uridine 5'-diphosphoglucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.9"^^xsd:string) "UDP-glucose diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.9"^^xsd:string) "uridine diphosphate-D-glucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.9"^^xsd:string) "UTP-glucose-1-phosphate uridylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.2.1.6"^^xsd:string) "acetolactic synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.6"^^xsd:string) "acetohydroxyacid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.6"^^xsd:string) "alpha-acetolactate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.6"^^xsd:string) "alpha-acetohydroxyacid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.6"^^xsd:string) "alpha-acetolactate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.6"^^xsd:string) "Catalysis of the reaction: 2 pyruvate = 2-acetolactate + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.6"^^xsd:string) "alpha-acetohydroxy acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.6"^^xsd:string) "pyruvate:pyruvate acetaldehydetransferase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.6"^^xsd:string) "acetolactate pyruvate-lyase (carboxylating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetolactate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.6"^^xsd:string) "acetohydroxy acid synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.9"^^xsd:string) "Catalysis of the reaction: 2 acetyl-CoA = CoA + acetoacetyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.9"^^xsd:string) "thiolase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.9"^^xsd:string) "beta-acetoacetyl coenzyme A thiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.9"^^xsd:string) "acetyl-CoA:acetyl-CoA C-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.9"^^xsd:string) "3-oxothiolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetyl-CoA C-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.9"^^xsd:string) "2-methylacetoacetyl-CoA thiolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.9"^^xsd:string) "acetoacetyl-CoA thiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.9"^^xsd:string) "acetyl-CoA acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.9"^^xsd:string) "acetyl coenzyme A thiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.9"^^xsd:string) "acetyl-CoA:N-acetyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.2.1"^^xsd:string) "acetyl coenzyme A acylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.1"^^xsd:string) "acetyl-CoA acylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.1"^^xsd:string) "acetyl-CoA thiol esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.1"^^xsd:string) "acetyl coenzyme A deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.1"^^xsd:string) Annotation( "RHEA:20292"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + H(2)O = acetate + CoA + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.1"^^xsd:string) "acetyl-CoA deacylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.1"^^xsd:string) "acetyl coenzyme A hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.1"^^xsd:string) "acetyl-CoA synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.1"^^xsd:string) "acetyl-activating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.1"^^xsd:string) "ACS"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.1"^^xsd:string) "acetyl CoA synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.1"^^xsd:string) "short-chain acyl-coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.1"^^xsd:string) "acetate thiokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.1"^^xsd:string) "acetyl CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.1"^^xsd:string) "short chain fatty acyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.1"^^xsd:string) "acetic thiokinase activity"^^xsd:string) AnnotationAssertion( "acetate to acetyl-CoA"^^xsd:string) AnnotationAssertion(rdfs:label "acetate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.1"^^xsd:string) "acetyl-coenzyme A synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.1"^^xsd:string) "acetyl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.1"^^xsd:string) "Catalysis of the reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.1"^^xsd:string) "acetate:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.1"^^xsd:string) "acyl-activating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.1"^^xsd:string) "acetyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.1"^^xsd:string) "acetyl activating enzyme"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "3-ketothiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "pro-3-ketoacyl-CoA thiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "3-oxoacyl-CoA thiolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetyl-CoA C-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "ketoacyl-CoA acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "KAT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "acetyl-CoA acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "beta-ketoacyl coenzyme A thiolase activity"^^xsd:string) AnnotationAssertion( "2-keto-acyl thiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "3-oxoacyl-coenzyme A thiolase activity"^^xsd:string) AnnotationAssertion( "3-ketoacyl-CoA thiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "acetoacetyl-CoA beta-ketothiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "2-methylacetoacetyl-CoA thiolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "3-ketoacyl coenzyme A thiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "beta-ketoadipyl-CoA thiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "6-oxoacyl-CoA thiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "beta-ketothiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "3-ketoacyl CoA thiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "3-ketoacyl thiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "beta-ketoadipyl coenzyme A thiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "oxoacyl-coenzyme A thiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "acyl-CoA:acetyl-CoA C-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "long-chain 3-oxoacyl-CoA thiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "thiolase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "beta-ketoacyl-CoA thiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.16"^^xsd:string) "ketoacyl-coenzyme A thiolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.4.1.2"^^xsd:string) "Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "acetyl-CoA carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.2"^^xsd:string) "acetyl-CoA:carbon-dioxide ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.2"^^xsd:string) "acetyl coenzyme A carboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.7"^^xsd:string) "acetylcholine acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.7"^^xsd:string) "acetyl.beta-methylcholinesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.7"^^xsd:string) "true cholinesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.7"^^xsd:string) "acetylthiocholinesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.7"^^xsd:string) "choline esterase I activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetylcholinesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.7"^^xsd:string) "AcCholE"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.7"^^xsd:string) "Catalysis of the reaction: acetylcholine + H2O = choline + acetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.7"^^xsd:string) "acetylcholine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.2.8"^^xsd:string) "acetylglutamate phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.8"^^xsd:string) "ATP:N-acetyl-L-glutamate 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.8"^^xsd:string) "Catalysis of the reaction: ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate-5-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.8"^^xsd:string) "N-acetylglutamate phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.8"^^xsd:string) "N-acetylglutamate 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.8"^^xsd:string) "N-acetylglutamic 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetylglutamate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.8"^^xsd:string) "N-acetylglutamate kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "acetylornithine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.11"^^xsd:string) "N2-acetylornithine 5-transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.11"^^xsd:string) "N-acetylornithine-delta-transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.11"^^xsd:string) "acetylornithine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.11"^^xsd:string) "acetylornithine delta-transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.11"^^xsd:string) "N-acetylornithine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.11"^^xsd:string) "acetylornithine 5-aminotransferase activity"^^xsd:string) AnnotationAssertion( "N2-acetylornithine 5-aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.11"^^xsd:string) "2-N-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.11"^^xsd:string) "N2-acetyl-L-ornithine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.11"^^xsd:string) "ACOAT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.11"^^xsd:string) Annotation( "RHEA:18052"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + N(2)-acetyl-L-ornithine = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.11"^^xsd:string) "N(2)-acetylornithine 5-transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.11"^^xsd:string) "succinylornithine aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.2"^^xsd:string) "acid monophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.2"^^xsd:string) "phosphate-monoester phosphohydrolase (acid optimum)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.2"^^xsd:string) "Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.2"^^xsd:string) "acid phosphomonoesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.2"^^xsd:string) "acid phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.2"^^xsd:string) "phosphomonoesterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acid phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.2"^^xsd:string) "glycerophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.2"^^xsd:string) "acid phosphomonoester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.2"^^xsd:string) "acid nucleoside diphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.2"^^xsd:string) "uteroferrin"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.2"^^xsd:string) "orthophosphoric-monoester phosphohydrolase (acid optimum)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aconitate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.3"^^xsd:string) "citrate(isocitrate) hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.3"^^xsd:string) Annotation( "GOC:pde"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate."^^xsd:string) AnnotationAssertion( "aconitase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.3"^^xsd:string) "citrate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.3"^^xsd:string) "citrate(isocitrate) hydro-lyase (cis-aconitate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.3"^^xsd:string) "cis-aconitase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.99.3"^^xsd:string) "acyl-CoA:acceptor 2,3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.3"^^xsd:string) "fatty-acyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "acyl-CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.3"^^xsd:string) "long-chain acyl coenzyme A dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.3"^^xsd:string) "acyl CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.3"^^xsd:string) "acyl dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.3"^^xsd:string) "fatty acyl coenzyme A dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.3"^^xsd:string) "medium-chain acyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.3"^^xsd:string) "acyl coenzyme A dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.3"^^xsd:string) "long-chain acyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.3"^^xsd:string) "medium-chain acyl-coenzyme A dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.3"^^xsd:string) "acyl-CoA:(acceptor) 2,3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.3"^^xsd:string) "Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.3"^^xsd:string) "general acyl CoA dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acyl-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15904"^^xsd:string) Annotation( "EC:6.2.1.3"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; long-chain fatty acids have chain lengths of C13 to C22."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.3.6"^^xsd:string) "fatty acyl-CoA oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.6"^^xsd:string) "acyl coenzyme A oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.6"^^xsd:string) "acyl-CoA:oxygen 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.6"^^xsd:string) "Catalysis of the reaction: acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide."^^xsd:string) AnnotationAssertion(rdfs:label "acyl-CoA oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.6"^^xsd:string) "fatty acyl-coenzyme A oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.7"^^xsd:string) "acylphosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.7"^^xsd:string) "1,3-diphosphoglycerate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.7"^^xsd:string) "acetic phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.7"^^xsd:string) "acetylphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.7"^^xsd:string) "GP 1-3"^^xsd:string) AnnotationAssertion(rdfs:label "acylphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.7"^^xsd:string) "Ho 1-3"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.7"^^xsd:string) "Catalysis of the reaction: an acyl phosphate + H2O = a carboxylate + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.7"^^xsd:string) "adenylic pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.7"^^xsd:string) "APRT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.7"^^xsd:string) "AMP-pyrophosphate phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.7"^^xsd:string) "Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "adenine phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.7"^^xsd:string) "AMP:diphosphate phospho-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.7"^^xsd:string) "transphosphoribosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.7"^^xsd:string) "AMP diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.7"^^xsd:string) "adenosine phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.7"^^xsd:string) "adenylate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.7"^^xsd:string) "AMP pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.7"^^xsd:string) "adenine phosphoribosylpyrophosphate transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.4"^^xsd:string) "adenosine aminohydrolase activity"^^xsd:string) AnnotationAssertion( "adenosine deaminase reaction"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.4"^^xsd:string) "Catalysis of the reaction: adenosine + H2O = inosine + NH3."^^xsd:string) AnnotationAssertion(rdfs:label "adenosine deaminase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "adenosine kinase activity"^^xsd:string) AnnotationAssertion( "adenosine 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.20"^^xsd:string) Annotation( "PMID:11223943"^^xsd:string) "Catalysis of the reaction: ATP + adenosine = ADP + AMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.20"^^xsd:string) "ATP:adenosine 5'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.20"^^xsd:string) "adenosine kinase (phosphorylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix."^^xsd:string) AnnotationAssertion(rdfs:label "ATP-dependent DNA helicase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix."^^xsd:string) AnnotationAssertion(rdfs:label "ATP-dependent RNA helicase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.4"^^xsd:string) "copper-translocating P-type ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.4"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu2+(in) -> ADP + phosphate + Cu2+(out)."^^xsd:string) AnnotationAssertion(rdfs:label "copper-exporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.4"^^xsd:string) "ATP phosphohydrolase (Cu2+-exporting)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.4"^^xsd:string) "Cu(2+)-exporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.4"^^xsd:string) "Cu2+-exporting ATPase activity"^^xsd:string) AnnotationAssertion( "copper exporting ATPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phospholipid translocating ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.1"^^xsd:string) "flippase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phospholipid-translocating ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.1"^^xsd:string) "Mg(2+)-ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.1"^^xsd:string) Annotation( "PMID:15919184"^^xsd:string) Annotation( "PMID:9099684"^^xsd:string) "Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, driven by the hydrolysis of ATP."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.1"^^xsd:string) "ATP phosphohydrolase (phospholipid-flipping)"^^xsd:string) AnnotationAssertion( "aminophospholipid-transporting ATPase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.1"^^xsd:string) "phospholipid-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.1"^^xsd:string) "Mg2+-ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.1"^^xsd:string) "magnesium-ATPase activity"^^xsd:string) AnnotationAssertion( " phospolipid flippase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.3.1.1"^^xsd:string) "S-adenosyl-L-homocysteine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.1.1"^^xsd:string) "S-adenosylhomocysteinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.1.1"^^xsd:string) "AdoHcyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "adenosylhomocysteinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.1.1"^^xsd:string) "SAHase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.1.1"^^xsd:string) "S-adenosylhomocysteine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.1.1"^^xsd:string) "adenosylhomocysteine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.1.1"^^xsd:string) "S-adenosylhomocysteine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.1.1"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.50"^^xsd:string) "S-adenosyl-L-methionine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.50"^^xsd:string) "S-adenosylmethionine decarboxylase activity"^^xsd:string) AnnotationAssertion( "adenosyl methionine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.50"^^xsd:string) "S-adenosyl-L-methionine carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.50"^^xsd:string) Annotation( "RHEA:15984"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + H(+) = S-adenosylmethioninamine + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.50"^^xsd:string) "S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)-methylsulfonium-salt-forming]"^^xsd:string) AnnotationAssertion(rdfs:label "adenosylmethionine decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.62"^^xsd:string) Annotation( "RHEA:16864"^^xsd:string) "Catalysis of the reaction: 8-amino-7-oxononanoate + S-adenosyl-L-methionine(1+) = 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.62"^^xsd:string) "adenosylmethionine--8-amino-7-oxononanoate aminotransferase activity"^^xsd:string) AnnotationAssertion( "adenosylmethionine-8-amino-7-oxononanoate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.62"^^xsd:string) "7,8-diaminononanoate aminotransferase activity"^^xsd:string) AnnotationAssertion( "adenosyl methionine-8-amino-7-oxononanoate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.62"^^xsd:string) "7,8-diaminonanoate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.62"^^xsd:string) "DAPA transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.62"^^xsd:string) "7,8-diamino-pelargonic acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.62"^^xsd:string) "DAPA aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.62"^^xsd:string) "diaminopelargonate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.62"^^xsd:string) "7-keto-8-aminopelargonic acid"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.62"^^xsd:string) "7,8-diaminopelargonic acid aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "adenosylmethionine-8-amino-7-oxononanoate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.62"^^xsd:string) "S-adenosyl-L-methionine:8-amino-7-oxononanoate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.62"^^xsd:string) "7-keto-8-aminopelargonic acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.62"^^xsd:string) "7,8-diaminononanoate transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.6.1.1"^^xsd:string) "adenyl cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.1"^^xsd:string) "3',5'-cyclic AMP synthetase activity"^^xsd:string) AnnotationAssertion( "adenylyl cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.1"^^xsd:string) "adenylylcyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.1"^^xsd:string) "Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.1"^^xsd:string) "ATP diphosphate-lyase (cyclizing) activity"^^xsd:string) AnnotationAssertion(rdfs:label "adenylate cyclase activity"^^xsd:string) AnnotationAssertion( "cAMP generating peptide activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.1"^^xsd:string) "ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.1"^^xsd:string) "ATP pyrophosphate-lyase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.4.3"^^xsd:string) "5'-AMP-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.3"^^xsd:string) "myokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.3"^^xsd:string) "adenylic kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.3"^^xsd:string) "ATP:AMP phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.3"^^xsd:string) "Catalysis of the reaction: ATP + AMP = 2 ADP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.3"^^xsd:string) "adenylokinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "adenylate kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.2"^^xsd:string) "Catalysis of the reaction: N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.2"^^xsd:string) "N6-(1,2-dicarboxyethyl)AMP AMP-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.2"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "succino AMP-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.2"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "adenylosuccinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "adenylosuccinate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.2"^^xsd:string) "6-N-(1,2-dicarboxyethyl)AMP AMP-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.4.4"^^xsd:string) Annotation( "RHEA:15756"^^xsd:string) "Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H(+) + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "adenylosuccinate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.4"^^xsd:string) "IMP--aspartate ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.4"^^xsd:string) "IMP:L-aspartate ligase (GDP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.4"^^xsd:string) "succino-AMP synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.4"^^xsd:string) "adenylosuccinate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.4"^^xsd:string) "succinoadenylic kinosynthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.25"^^xsd:string) "5'-phosphoadenosine sulfate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.25"^^xsd:string) "ATP:adenylyl-sulfate 3'-phosphotransferase activity"^^xsd:string) AnnotationAssertion( "adenosine-5'-phosphosulphate 3'-phosphotransferase activity"^^xsd:string) AnnotationAssertion( "adenosine-5'-phosphosulfate 3'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.25"^^xsd:string) "adenosine 5'-phosphosulfate kinase activity"^^xsd:string) AnnotationAssertion( "adenylyl-sulphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.25"^^xsd:string) "adenosine phosphosulfate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.25"^^xsd:string) "APS kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.25"^^xsd:string) "adenosine-5'-phosphosulfate-3'-phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.25"^^xsd:string) "adenosine phosphosulfokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.25"^^xsd:string) "adenylylsulfate kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.25"^^xsd:string) "Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate."^^xsd:string) AnnotationAssertion( "adenylyl-sulfate kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "adenylylsulfate kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.2"^^xsd:string) "alanine-alpha-ketoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.2"^^xsd:string) "pyruvate-glutamate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.2"^^xsd:string) "alanine-pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion( "alanine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.2"^^xsd:string) "pyruvate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.2"^^xsd:string) "L-alanine-alpha-ketoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.2"^^xsd:string) "glutamic--pyruvic transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.2"^^xsd:string) "pyruvate-alanine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.2"^^xsd:string) "glutamic-pyruvic aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.2"^^xsd:string) "glutamic acid-pyruvic acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.2"^^xsd:string) Annotation( "RHEA:19456"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.2"^^xsd:string) "GPT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.2"^^xsd:string) "L-alanine transaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-alanine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.2"^^xsd:string) "glutamic--alanine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.2"^^xsd:string) "alanine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.2"^^xsd:string) "L-alanine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.2"^^xsd:string) "beta-alanine aminotransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.2"^^xsd:string) "ALT"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.1"^^xsd:string) "ethanol dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.1"^^xsd:string) "primary alcohol dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.1"^^xsd:string) "NAD-dependent alcohol dehydrogenase"^^xsd:string) AnnotationAssertion(rdfs:label "alcohol dehydrogenase (NAD) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.1"^^xsd:string) "NADH-aldehyde dehydrogenase"^^xsd:string) AnnotationAssertion( "aldo-keto reductase (NAD) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.1"^^xsd:string) "aliphatic alcohol dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.1"^^xsd:string) "NADH-alcohol dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.1"^^xsd:string) "ADH"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.1"^^xsd:string) "alcohol:NAD+ oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.1"^^xsd:string) "Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "alcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.1"^^xsd:string) "NAD-specific aromatic alcohol dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.1"^^xsd:string) "yeast alcohol dehydrogenase"^^xsd:string) AnnotationAssertion( "aldehyde dehydrogenase (NAD) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.1"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+; can proceed in the absence of a metal ion."^^xsd:string) AnnotationAssertion(rdfs:label "alcohol dehydrogenase activity, metal ion-independent"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alcohol dehydrogenase activity, zinc-dependent"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.1"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alcohol dehydrogenase activity, iron-dependent"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.1"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of iron."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.84"^^xsd:string) "AATASE activity"^^xsd:string) AnnotationAssertion(rdfs:label "alcohol O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.84"^^xsd:string) "alcohol acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.84"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + an alcohol = CoA + an acetyl ester."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.84"^^xsd:string) "acetyl-CoA:alcohol O-acetyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.2"^^xsd:string) "3beta-hydroxysteroid sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.2"^^xsd:string) "5alpha-androstenol sulfotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alcohol sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.2"^^xsd:string) "estrogen sulfokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.2"^^xsd:string) "hydroxysteroid sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.2"^^xsd:string) "steroid sulfokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.2"^^xsd:string) "3-hydroxysteroid sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.2"^^xsd:string) "delta5-3beta-hydroxysteroid sulfokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.2"^^xsd:string) "HST"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.2"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.2"^^xsd:string) "steroid alcohol sulfotransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.2"^^xsd:string) "estrogen sulfotransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.2"^^xsd:string) "3'-phosphoadenylyl-sulfate:alcohol sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.2"^^xsd:string) "sterol sulfokinase activity"^^xsd:string) AnnotationAssertion( "alcohol sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.2"^^xsd:string) "3beta-hydroxy steroid sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.2"^^xsd:string) "dehydroepiandrosterone sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.2"^^xsd:string) "alcohol/hydroxysteroid sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.2"^^xsd:string) "sterol sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-chloroallyl aldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0432"^^xsd:string) "Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2 e- + 3-chloroacrylic acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.3"^^xsd:string) "Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.3"^^xsd:string) "NAD-dependent aldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.3"^^xsd:string) "propionaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.3"^^xsd:string) "NAD-dependent 4-hydroxynonenal dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aldehyde dehydrogenase (NAD) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.3"^^xsd:string) "m-methylbenzaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.3"^^xsd:string) "NAD-aldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.3"^^xsd:string) "CoA-independent aldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.3"^^xsd:string) "aldehyde dehydrogenase (NAD+)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.3"^^xsd:string) "NAD-linked aldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.3"^^xsd:string) "aldehyde:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.5"^^xsd:string) "aldehyde:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.5"^^xsd:string) "ALDH"^^xsd:string) AnnotationAssertion(rdfs:label "aldehyde dehydrogenase [NAD(P)+] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.5"^^xsd:string) "Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aldehyde oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.1"^^xsd:string) "Catalysis of the reaction: an aldehyde + H2O + O2 = a carboxylic acid + hydrogen peroxide."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.1"^^xsd:string) "aldehyde:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.1"^^xsd:string) "quinoline oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.21"^^xsd:string) "aldose reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alditol:NADP+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.21"^^xsd:string) "Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.21"^^xsd:string) "polyol dehydrogenase (NADP(+)) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aldo-keto reductase (NADP) activity"^^xsd:string) AnnotationAssertion( "aldo-keto reductase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or a ketone + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) "NADPH-dependent aldo-keto reductase activity"^^xsd:string) AnnotationAssertion( "aldo-keto reductase activity"^^xsd:string) AnnotationAssertion( "alcohol dehydrogenase (NADP+) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.3"^^xsd:string) "Catalysis of the reaction: alpha-D-glucose = beta-D-glucose. Also acts on L-arabinose, D-xylose, D-galactose, maltose and lactose."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.3"^^xsd:string) "aldose mutarotase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.3"^^xsd:string) "mutarotase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aldose 1-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.1"^^xsd:string) "glycerophosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alkaline phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.1"^^xsd:string) "alkaline phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.1"^^xsd:string) "Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.1"^^xsd:string) "phosphomonoesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.1"^^xsd:string) "phosphate-monoester phosphohydrolase (alkaline optimum)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.1"^^xsd:string) "orthophosphoric-monoester phosphohydrolase (alkaline optimum)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.1"^^xsd:string) "alkaline phosphomonoesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.1"^^xsd:string) "alkaline phenyl phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.4"^^xsd:string) "allantoate amidinohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.4"^^xsd:string) Annotation( "RHEA:11019"^^xsd:string) "Catalysis of the reaction: allantoate + H(2)O = (S)-ureidoglycolate + urea."^^xsd:string) AnnotationAssertion( "allantoine amidinohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "allantoicase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "allantoinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.5"^^xsd:string) "(S)-allantoin amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.5"^^xsd:string) "Catalysis of the reaction: allantoin + H2O = allantoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "allophanate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.54"^^xsd:string) "urea-1-carboxylate amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.54"^^xsd:string) "allophanate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.54"^^xsd:string) Annotation( "RHEA:19032"^^xsd:string) "Catalysis of the reaction: H(2)O + 3 H(+) + urea-1-carboxylate = 2 CO(2) + 2 NH(4)(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.4"^^xsd:string) "Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.4"^^xsd:string) "amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.4"^^xsd:string) "acylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.4"^^xsd:string) "acylamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.4"^^xsd:string) "N-acetylaminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.4"^^xsd:string) "fatty acylamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.4"^^xsd:string) "acylamide amidohydrolase activity"^^xsd:string) AnnotationAssertion( "acetamidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "amidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.1"^^xsd:string) "acetylglutamate acetylglutamate synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetyl-CoA:L-glutamate N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.1"^^xsd:string) "amino acid acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.1"^^xsd:string) "AGAS"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.1"^^xsd:string) "N-acetylglutamate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.1"^^xsd:string) "amino-acid N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.1"^^xsd:string) Annotation( "RHEA:24295"^^xsd:string) "Catalysis of the reaction: L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.31"^^xsd:string) "L-alpha-aminoadipate delta-semialdehyde oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.31"^^xsd:string) "aminoadipate semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-aminoadipate-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.31"^^xsd:string) "L-alpha-aminoadipate delta-semialdehyde:NAD oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.31"^^xsd:string) "aminoadipate-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.31"^^xsd:string) "L-2-aminoadipate-6-semialdehyde:NAD(P)+ 6-oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.31"^^xsd:string) "alpha-aminoadipate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.31"^^xsd:string) "AAR"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.31"^^xsd:string) "2-aminoadipic semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.31"^^xsd:string) "Catalysis of the reaction: L-2-aminoadipate 6-semialdehyde + NADP+ + H2O = L-2-aminoadipate + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.31"^^xsd:string) "2-aminoadipate semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.31"^^xsd:string) "alpha-aminoadipate-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.31"^^xsd:string) "L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine dinucleotide oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.14"^^xsd:string) "glutamine phosphoribosyldiphosphate amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.14"^^xsd:string) "5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.14"^^xsd:string) Annotation( "RHEA:14908"^^xsd:string) "Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.14"^^xsd:string) "phosphoribose pyrophosphate amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.14"^^xsd:string) "phosphoribosylpyrophosphate glutamyl amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.14"^^xsd:string) "glutamine ribosylpyrophosphate 5-phosphate amidotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "amidophosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.14"^^xsd:string) "5'-phosphoribosylpyrophosphate amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.14"^^xsd:string) "5-phosphoribosyl-1-pyrophosphate amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.14"^^xsd:string) "phosphoribosyldiphosphate 5-amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.14"^^xsd:string) "phosphoribosyl pyrophosphate amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.14"^^xsd:string) "glutamine 5-phosphoribosylpyrophosphate amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.14"^^xsd:string) "glutamine phosphoribosylpyrophosphate amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.14"^^xsd:string) "alpha-5-phosphoribosyl-1-pyrophosphate amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.14"^^xsd:string) "5-phosphororibosyl-1-pyrophosphate amidotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.29"^^xsd:string) "aminoacyl-tRNA aminoacylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.29"^^xsd:string) "N-substituted aminoacyl transfer RNA hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aminoacyl-tRNA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.29"^^xsd:string) "peptidyl-tRNA hydrolase activity"^^xsd:string) AnnotationAssertion( "aminoacyl-tRNA hydrolase reaction"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.29"^^xsd:string) "aminoacyl-transfer ribonucleate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.29"^^xsd:string) "Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA."^^xsd:string) AnnotationAssertion(Annotation( "PMID:15292242"^^xsd:string) "D-tyrosyl-tRNA hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.14"^^xsd:string) "N-acyl-L-amino-acid amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.14"^^xsd:string) "dehydropeptidase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.14"^^xsd:string) "histozyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.14"^^xsd:string) "short acyl amidoacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.14"^^xsd:string) "L-aminoacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.14"^^xsd:string) "Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.14"^^xsd:string) "amido acid deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.14"^^xsd:string) "L-amino-acid acylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.14"^^xsd:string) "acylase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.14"^^xsd:string) "long acyl amidoacylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aminoacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.14"^^xsd:string) "hippurase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.14"^^xsd:string) "benzamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.14"^^xsd:string) "alpha-N-acylaminoacid hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.14"^^xsd:string) "aminoacylase I activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.2.10"^^xsd:string) "Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.10"^^xsd:string) "glycine-cleavage system T-protein activity"^^xsd:string) AnnotationAssertion(rdfs:label "aminomethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.10"^^xsd:string) "S-aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.10"^^xsd:string) "T-protein"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.10"^^xsd:string) "tetrahydrofolate aminomethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.10"^^xsd:string) "glycine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.10"^^xsd:string) "protein-S8-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.10"^^xsd:string) "protein-8-S-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.18"^^xsd:string) "phosphoribosyl-anthranilate diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.18"^^xsd:string) "phosphoribosylanthranilate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.18"^^xsd:string) "N-(5-phospho-D-ribosyl)-anthranilate:diphosphate phospho-alpha-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.18"^^xsd:string) "PRT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.18"^^xsd:string) "phosphoribosyl-anthranilate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.18"^^xsd:string) "phosphoribosylanthranilate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.18"^^xsd:string) "anthranilate-PP-ribose-P phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "anthranilate phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.18"^^xsd:string) Annotation( "RHEA:11771"^^xsd:string) "Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.18"^^xsd:string) "anthranilate phosphoribosylpyrophosphate phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.18"^^xsd:string) "anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3.27"^^xsd:string) "Catalysis of the reaction: chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate."^^xsd:string) AnnotationAssertion(rdfs:label "anthranilate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.27"^^xsd:string) "anthranilate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.27"^^xsd:string) "chorismate pyruvate-lyase (amino-accepting) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.34"^^xsd:string) "arachidonate:oxygen 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.34"^^xsd:string) "leukotriene A4 synthase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.34"^^xsd:string) "5-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.34"^^xsd:string) "leukotriene-A(4) synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.34"^^xsd:string) "arachidonic acid 5-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.34"^^xsd:string) "arachidonic 5-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.34"^^xsd:string) "LTA synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.34"^^xsd:string) "delta(5)-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.34"^^xsd:string) "delta5-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.34"^^xsd:string) "Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.34"^^xsd:string) "C-5-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.34"^^xsd:string) "5Delta-lipoxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arachidonate 5-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.34"^^xsd:string) "5-delta-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.34"^^xsd:string) "leukotriene-A4 synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.31"^^xsd:string) "arachidonate:oxygen 12-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.31"^^xsd:string) "12Delta-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.31"^^xsd:string) "delta12-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.31"^^xsd:string) Annotation( "RHEA:10431"^^xsd:string) "Catalysis of the reaction: arachidonate + O(2) = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.31"^^xsd:string) "12-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.31"^^xsd:string) "C-12 lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.31"^^xsd:string) "12S-lipoxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arachidonate 12-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.31"^^xsd:string) "leukotriene A4 synthase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.31"^^xsd:string) "LTA4 synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.1"^^xsd:string) "canavanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.1"^^xsd:string) "arginine amidinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.1"^^xsd:string) "arginine transamidinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.1"^^xsd:string) "L-arginase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.1"^^xsd:string) "L-arginine amidinohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arginase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.1"^^xsd:string) "Catalysis of the reaction: L-arginine + H2O = L-ornithine + urea."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arginine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.3"^^xsd:string) "adenosine 5'-triphosphate:L-arginine"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.3"^^xsd:string) "ATP:L-arginine N-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.3"^^xsd:string) "arginine phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.3"^^xsd:string) "adenosine 5'-triphosphate-arginine phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.3"^^xsd:string) Annotation( "RHEA:22943"^^xsd:string) "Catalysis of the reaction: L-arginine + ATP = N(omega)-phospho-L-arginine + ADP + 2 H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.4.5"^^xsd:string) "argininosuccinate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.5"^^xsd:string) "L-citrulline:L-aspartate ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "argininosuccinate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.5"^^xsd:string) "argininosuccinic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.5"^^xsd:string) "arginosuccinate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.5"^^xsd:string) "arginine succinate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.5"^^xsd:string) "citrulline--aspartate ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.5"^^xsd:string) "Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.2.1"^^xsd:string) "2-(Nomega-L-arginino)succinate arginine-lyase (fumarate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.1"^^xsd:string) "N-(L-argininosuccinate) arginine-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.1"^^xsd:string) "arginine-succinate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.1"^^xsd:string) "Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.1"^^xsd:string) "2-(omega-N-L-arginino)succinate arginine-lyase (fumarate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.1"^^xsd:string) "arginosuccinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.1"^^xsd:string) "omega-N-(L-arginino)succinate arginine-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "argininosuccinate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.1"^^xsd:string) "argininosuccinic acid lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "arginyl-tRNA-protein transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arginyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.8"^^xsd:string) "arginyl-transfer ribonucleate-protein transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.8"^^xsd:string) "Catalysis of the reaction: L-arginyl-tRNA + protein = tRNA + L-arginyl-protein."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.8"^^xsd:string) "arginyl-transfer ribonucleate-protein aminoacyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.8"^^xsd:string) "arginine transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.8"^^xsd:string) "arginyl-tRNA protein transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.8"^^xsd:string) "arginyl-tRNA--protein transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.8"^^xsd:string) "L-arginyl-tRNA:protein arginyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.28"^^xsd:string) "aromatic-L-amino-acid carboxy-lyase (tryptamine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.28"^^xsd:string) "Catalysis of the reaction: L-tryptophan = tryptamine + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.28"^^xsd:string) "aromatic amino acid decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.28"^^xsd:string) "5-hydroxytryptophan decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.28"^^xsd:string) "hydroxytryptophan decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.28"^^xsd:string) "tryptophan decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.28"^^xsd:string) "aromatic-L-amino-acid carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.28"^^xsd:string) "DOPA decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.28"^^xsd:string) "L-DOPA decarboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aromatic-L-amino-acid decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.87"^^xsd:string) "arylalkylamine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.87"^^xsd:string) "AANAT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.87"^^xsd:string) "melatonin rhythm enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "aralkylamine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.87"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + an aralkylamine = CoA + an N-acetylaralkylamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.87"^^xsd:string) "serotonin acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.87"^^xsd:string) "acetyl-CoA:2-arylethylamine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.87"^^xsd:string) "serotonin N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.87"^^xsd:string) "serotonin acetylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arylamine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.5"^^xsd:string) "2-naphthylamine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.5"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + an arylamine = CoA + an N-acetylarylamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.5"^^xsd:string) "indoleamine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.5"^^xsd:string) "acetyl-CoA:arylamine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.5"^^xsd:string) "p-aminosalicylate N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.5"^^xsd:string) "arylamine acetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.5"^^xsd:string) "acetyl CoA-arylamine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.5"^^xsd:string) "arylamine acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.5"^^xsd:string) "4-aminobiphenyl N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.5"^^xsd:string) "beta-naphthylamine N-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.9"^^xsd:string) "formylkynureninase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.9"^^xsd:string) "aryl-formylamine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.9"^^xsd:string) "formylkynurenine formamidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arylformamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.9"^^xsd:string) "kynurenine formamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.9"^^xsd:string) "formamidase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.9"^^xsd:string) "formylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.9"^^xsd:string) "Catalysis of the reaction: N-formyl-L-kynurenine + H2O = formate + L-kynurenine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.9"^^xsd:string) "formamidase II"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.1"^^xsd:string) "dopamine sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.1"^^xsd:string) "phenol sulfokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.1"^^xsd:string) "p-nitrophenol sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.1"^^xsd:string) "PST"^^xsd:string) AnnotationAssertion( "aryl sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.1"^^xsd:string) "1-naphthol phenol sulfotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aryl sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.1"^^xsd:string) "2-naphtholsulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.1"^^xsd:string) "sulfokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.1"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.1"^^xsd:string) "ritodrine sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.1"^^xsd:string) "phenol sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.1"^^xsd:string) "arylsulfotransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.1"^^xsd:string) "4-nitrocatechol sulfokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.1"^^xsd:string) "3'-phosphoadenylyl-sulfate:phenol sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.8.1"^^xsd:string) "esterase E4"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.1"^^xsd:string) "paraoxon esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.1"^^xsd:string) "phosphotriesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.1"^^xsd:string) "organophosphorus hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.1"^^xsd:string) "organophosphate esterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aryldialkylphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.1"^^xsd:string) "pirimiphos-methyloxon esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.1"^^xsd:string) "aryltriphosphate dialkylphosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.1"^^xsd:string) "Catalysis of the reaction: aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.1"^^xsd:string) "aryltriphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.1"^^xsd:string) "A-esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.1"^^xsd:string) "organophosphate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.1"^^xsd:string) "organophosphorus acid anhydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.1"^^xsd:string) "paraoxon hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.1"^^xsd:string) "OPH"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.1"^^xsd:string) "esterase B1"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.1"^^xsd:string) "paraoxonase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.2"^^xsd:string) "aromatic esterase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.2"^^xsd:string) "A-esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.2"^^xsd:string) "aryl-ester hydrolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.2"^^xsd:string) "Catalysis of the reaction: a phenyl acetate + H2O = a phenol + acetate."^^xsd:string) AnnotationAssertion(rdfs:label "arylesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.2"^^xsd:string) "paraoxonase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.6.1"^^xsd:string) "Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.1"^^xsd:string) "nitrocatechol sulfatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arylsulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.1"^^xsd:string) "aryl-sulfate sulphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.1"^^xsd:string) "aryl-sulphate sulphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.1"^^xsd:string) "phenolsulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.1"^^xsd:string) "p-nitrophenyl sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.1"^^xsd:string) "4-methylumbelliferyl sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.1"^^xsd:string) "sulfatase activity"^^xsd:string) AnnotationAssertion( "arylsulphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.1"^^xsd:string) "phenylsulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.1"^^xsd:string) "aryl-sulfate sulfohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.1"^^xsd:string) "estrogen sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.1"^^xsd:string) "arylsulfohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.5.4"^^xsd:string) "Catalysis of the reaction: ATP + L-aspartate + L-glutamine = AMP + diphosphate + L-asparagine + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.4"^^xsd:string) "AS"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.4"^^xsd:string) "asparagine synthetase (glutamine-hydrolyzing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.4"^^xsd:string) "AS-B activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.4"^^xsd:string) "L-aspartate:L-glutamine amido-ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.4"^^xsd:string) "asparagine synthase (glutamine-hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.4"^^xsd:string) "asparagine synthetase B activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.4"^^xsd:string) "glutamine-dependent asparagine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.4"^^xsd:string) "asparagine synthetase (glutamine-hydrolysing)"^^xsd:string) AnnotationAssertion(rdfs:label "asparagine synthase (glutamine-hydrolyzing) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.1"^^xsd:string) "alpha-asparaginase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.1"^^xsd:string) "colaspase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.1"^^xsd:string) "crasnitin"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.1"^^xsd:string) "elspar"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.1"^^xsd:string) "Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.1"^^xsd:string) "asparaginase II"^^xsd:string) AnnotationAssertion(rdfs:label "asparaginase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.1"^^xsd:string) "leunase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.1"^^xsd:string) "L-asparaginase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.1"^^xsd:string) "L-asparagine amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.11"^^xsd:string) "L-aspartate 1-carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.11"^^xsd:string) "L-aspartate alpha-decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.11"^^xsd:string) "aspartic alpha-decarboxylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.11"^^xsd:string) "Catalysis of the reaction: L-aspartate = beta-alanine + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "aspartate 1-decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.11"^^xsd:string) "L-aspartate 1-carboxy-lyase (beta-alanine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.11"^^xsd:string) "aspartate alpha-decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "L-aspartate-2-ketoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "glutamate-oxalacetate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "aspartic acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "AAT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "aspartyl aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "glutamic-aspartic aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "L-aspartate-alpha-ketoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "aspartic aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "glutamic--oxaloacetic transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "aspartate-2-oxoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "2-oxoglutarate-glutamate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "L-aspartate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "glutamic oxalic transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "glutamate-oxalate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "aspartate alpha-ketoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "L-aspartate-2-oxoglutarate-transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "GOT (enzyme)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "transaminase A activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "oxaloacetate transferase activity"^^xsd:string) AnnotationAssertion( "aspartate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "L-aspartic aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "aspartate:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "L-aspartate-2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "glutamic--aspartic transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "AspT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "glutamic-oxalacetic transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "glutamate oxaloacetate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "oxaloacetate-aspartate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.1"^^xsd:string) "aspartate transaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-aspartate:2-oxoglutarate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.3.2"^^xsd:string) "aspartate transcarbamylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.2"^^xsd:string) "carbamoylaspartotranskinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.2"^^xsd:string) "L-aspartate transcarbamoylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aspartate carbamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.2"^^xsd:string) "L-aspartate transcarbamylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.2"^^xsd:string) "aspartic acid transcarbamoylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.2"^^xsd:string) Annotation( "RHEA:20016"^^xsd:string) "Catalysis of the reaction: L-aspartate + carbamoyl phosphate = N-carbamoyl-L-aspartate + H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.2"^^xsd:string) "ATCase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.2"^^xsd:string) "carbamylaspartotranskinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.2"^^xsd:string) "aspartic transcarbamylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.2"^^xsd:string) "carbamoyl-phosphate:L-aspartate carbamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.2"^^xsd:string) "aspartate carbamyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.2"^^xsd:string) "aspartate transcarbamoylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.2"^^xsd:string) "aspartic carbamyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.1.1"^^xsd:string) "Catalysis of the reaction: ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.1"^^xsd:string) "asparagine synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aspartate-ammonia ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.1"^^xsd:string) "L-asparagine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.1"^^xsd:string) "L-aspartate:ammonia ligase (AMP-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.2.4"^^xsd:string) "aspartokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.4"^^xsd:string) "beta-aspartokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.4"^^xsd:string) "aspartic kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.4"^^xsd:string) Annotation( "RHEA:23779"^^xsd:string) "Catalysis of the reaction: L-aspartate + ATP = 4-phospho-L-aspartate + ADP + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "aspartate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.4"^^xsd:string) "ATP:L-aspartate 4-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.11"^^xsd:string) "L-aspartate-beta-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aspartate-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.11"^^xsd:string) "aspartic semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.11"^^xsd:string) "aspartate semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.11"^^xsd:string) "L-aspartate-beta-semialdehyde:NADP oxidoreductase (phosporylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.11"^^xsd:string) "aspartic beta-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.11"^^xsd:string) "L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.11"^^xsd:string) Annotation( "RHEA:24287"^^xsd:string) "Catalysis of the reaction: L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.11"^^xsd:string) "ASA dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.24"^^xsd:string) "bilirubin:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.24"^^xsd:string) "Catalysis of the reaction: bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(rdfs:label "biliverdin reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.4.14"^^xsd:string) "biotin carboxylase (component of acetyl CoA carboxylase) activity"^^xsd:string) AnnotationAssertion(rdfs:label "biotin carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.14"^^xsd:string) "Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.14"^^xsd:string) "biotin-carboxyl-carrier-protein:carbon-dioxide ligase (ADP-forming) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.1.6"^^xsd:string) Annotation( "RHEA:22063"^^xsd:string) "Catalysis of the reaction: 2 S-adenosyl-L-methionine + dethiobiotin + S(2-) = 2 5'-deoxyadenosine + 2 L-methionine + biotin + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "biotin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.6"^^xsd:string) "dethiobiotin:sulfur sulfurtransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.6"^^xsd:string) "biotin synthetase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.4.15"^^xsd:string) "biotin:apocarboxylase ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.15"^^xsd:string) "Catalysis of the reaction: ATP + biotin + apo-(acetyl-CoA:carbon-dioxide ligase (ADP forming)) = AMP + diphosphate + (acetyl-CoA:carbon-dioxide ligase (ADP forming))."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.15"^^xsd:string) "acetyl-CoA carboxylase biotin holoenzyme synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.15"^^xsd:string) "acetyl coenzyme A holocarboxylase synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.15"^^xsd:string) "biotin-acetyl coenzyme A carboxylase synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.15"^^xsd:string) "biotin--protein ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.15"^^xsd:string) "HCS"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.15"^^xsd:string) "biotin:apo-acetyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "biotin-[acetyl-CoA-carboxylase] ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.15"^^xsd:string) "biotin holoenzyme synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.15"^^xsd:string) "biotin-acetyl-CoA-carboxylase ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.15"^^xsd:string) "biotin-acetyl-CoA carboxylase synthetase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.15"^^xsd:string) "acetyl CoA holocarboxylase synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.15"^^xsd:string) "biotin--[acetyl-CoA carboxylase] synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.11"^^xsd:string) "biotin-methylcrotonoyl-CoA-carboxylase synthetase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.11"^^xsd:string) "biotin-methylcrotonoyl-CoA-carboxylase ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.11"^^xsd:string) "beta-methylcrotonyl coenzyme A holocarboxylase synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.11"^^xsd:string) "biotin:apo-3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.11"^^xsd:string) "biotin-beta-methylcrotonyl coenzyme A carboxylase synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.11"^^xsd:string) "Catalysis of the reaction: ATP + biotin + apo-(3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming))."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.11"^^xsd:string) "biotin--[methylcrotonoyl-CoA-carboxylase] synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.11"^^xsd:string) "holocarboxylase-synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.4.9"^^xsd:string) "biotin-transcarboxylase synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.9"^^xsd:string) "biotin-methylmalonyl-CoA-carboxyltransferase synthetase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.9"^^xsd:string) "methylmalonyl coenzyme A holotranscarboxylase synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.9"^^xsd:string) "biotin:apomethylmalonyl-CoA:pyruvate carboxytransferase ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.9"^^xsd:string) "biotin--[methylmalonyl-CoA-carboxytransferase] synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.9"^^xsd:string) "biotin-methylmalonyl-CoA-carboxytransferase ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.9"^^xsd:string) "biotin-methylmalonyl-CoA-carboxytransferase synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.9"^^xsd:string) "biotin--[methylmalonyl-CoA-carboxyltransferase] ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.9"^^xsd:string) "biotin--[methylmalonyl-CoA-carboxyltransferase] synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.9"^^xsd:string) "Catalysis of the reaction: ATP + biotin + apo-(methylmalonyl-CoA:pyruvate carboxytransferase) = AMP + diphosphate + (methylmalonyl-CoA:pyruvate carboxytransferase)."^^xsd:string) AnnotationAssertion( "biotin-[methylmalonyl-CoA-carboxyltransferase] ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.9"^^xsd:string) "biotin-methylmalonyl-CoA-carboxyltransferase ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.9"^^xsd:string) "biotin-methylmalonyl coenzyme A carboxyltransferase synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.9"^^xsd:string) "biotin:apomethylmalonyl-CoA:pyruvate carboxyltransferase ligase (AMP-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.4.10"^^xsd:string) "biotin-propionyl-CoA-carboxylase (ATP-hydrolysing) ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.10"^^xsd:string) "holocarboxylase synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.10"^^xsd:string) "biotin:apo-propanoyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.10"^^xsd:string) "biotin-propionyl coenzyme A carboxylase synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.10"^^xsd:string) "biotin-propionyl-CoA-carboxylase (ATP-hydrolysing) synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.10"^^xsd:string) "propionyl coenzyme A holocarboxylase synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.10"^^xsd:string) "propionyl-CoA holocarboxylase synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.10"^^xsd:string) "biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.10"^^xsd:string) "Catalysis of the reaction: ATP + biotin + apo-(propanoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (propanoyl-CoA:carbon-dioxide ligase (ADP-forming))."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.17"^^xsd:string) "diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.17"^^xsd:string) "Ap(4)A hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.17"^^xsd:string) "diguanosinetetraphosphatase (asymmetrical) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.17"^^xsd:string) "bis(5'-guanosyl)-tetraphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.17"^^xsd:string) "P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.17"^^xsd:string) "bis(5'-adenosyl)-tetraphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.17"^^xsd:string) "diadenosine P1,P4-tetraphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.17"^^xsd:string) "Ap4A hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.17"^^xsd:string) "dinucleosidetetraphosphatase (asymmetrical) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.17"^^xsd:string) Annotation( "PMID:4955726"^^xsd:string) "Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.17"^^xsd:string) "diadenosine 5',5'''-P(1),P(4)-tetraphosphate asymmetrical hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.17"^^xsd:string) "Ap(4)Aase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.17"^^xsd:string) "diadenosinetetraphosphatase (asymmetrical) activity"^^xsd:string) AnnotationAssertion(rdfs:label "bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity"^^xsd:string) AnnotationAssertion( "diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.17"^^xsd:string) "Ap4Aase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.17"^^xsd:string) "dinucleoside tetraphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.17"^^xsd:string) "1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bisphosphoglycerate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.4"^^xsd:string) "BPGM activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.4"^^xsd:string) "2,3-bisphosphoglycerate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.4"^^xsd:string) "3-phospho-D-glycerate 1,2-phosphomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.4"^^xsd:string) "2,3-diphosphoglycerate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.4"^^xsd:string) "biphosphoglycerate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.4"^^xsd:string) "DPGM"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.4"^^xsd:string) "glycerate phosphomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.4"^^xsd:string) "diphosphoglyceric mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.4"^^xsd:string) "2,3-bisphosphoglycerate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.4"^^xsd:string) "2,3-diphosphoglyceromutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.4"^^xsd:string) "bisphosphoglyceromutase"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.4"^^xsd:string) "2,3-diphosphoglycerate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.4"^^xsd:string) "bisphosphoglycerate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.4"^^xsd:string) "diphosphoglycerate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.4"^^xsd:string) "diphosphoglyceromutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.4"^^xsd:string) "Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bisphosphoglycerate 2-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.13"^^xsd:string) Annotation( "RHEA:21907"^^xsd:string) "Catalysis of the reaction: 2,3-bisphospho-D-glycerate + H(2)O = 3-phospho-D-glycerate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.13"^^xsd:string) "2,3-bisphospho-D-glycerate 2-phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "branched-chain-amino-acid transaminase activity"^^xsd:string) AnnotationAssertion( "branched-chain amino acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.42"^^xsd:string) "glutamate-branched-chain amino acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.42"^^xsd:string) "branched-chain amino acid-glutamate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.42"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.42"^^xsd:string) "transaminase B activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.42"^^xsd:string) "branched-chain-amino-acid:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.42"^^xsd:string) "L-branched chain amino acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.42"^^xsd:string) "branched-chain aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.8.1"^^xsd:string) "3-hydroxyacyl CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.8.1"^^xsd:string) "short-chain acyl-coenzyme A dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.8.1"^^xsd:string) "butanoyl-CoA:acceptor 2,3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.8.1"^^xsd:string) "short-chain-acyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.8.1"^^xsd:string) "enoyl-coenzyme A reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.8.1"^^xsd:string) "Catalysis of the reaction: butanoyl-CoA + electron-transfer flavoprotein = 2-butenoyl-CoA + reduced electron-transfer flavoprotein."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.8.1"^^xsd:string) "short-chain acyl CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "butyryl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.8.1"^^xsd:string) "butyryl dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.8.1"^^xsd:string) "unsaturated acyl-CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.8.1"^^xsd:string) "unsaturated acyl coenzyme A reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.8.1"^^xsd:string) "butanoyl-CoA:(acceptor) 2,3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.8.1"^^xsd:string) "ethylene reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.8.1"^^xsd:string) "butyryl coenzyme A dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.4.16"^^xsd:string) "carbamoylphosphate synthetase (ammonia) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.16"^^xsd:string) "carbamoylphosphate synthase (ammonia)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.16"^^xsd:string) "carbamoylphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.16"^^xsd:string) "carbamoyl-phosphate synthetase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.16"^^xsd:string) "carbmoylphosphate synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "carbamoyl-phosphate synthase (ammonia) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.16"^^xsd:string) "carbamylphosphate synthetase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.16"^^xsd:string) Annotation( "RHEA:10627"^^xsd:string) "Catalysis of the reaction: 2 ATP + CO(2) + H(2)O + NH(4)(+) = 2 ADP + carbamoyl phosphate + 5 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.16"^^xsd:string) "carbamylphosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.16"^^xsd:string) "CPS I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.16"^^xsd:string) "carbamoyl-phosphate synthetase (ammonia) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.16"^^xsd:string) "carbon-dioxide--ammonia ligase activity"^^xsd:string) AnnotationAssertion( "carbamoyl phosphate synthase (ammonia) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.16"^^xsd:string) "carbon-dioxide:ammonia ligase (ADP-forming, carbamate-phosphorylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.5.5"^^xsd:string) "carbamoyl-phosphate synthetase (glutamine-hydrolysing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.5"^^xsd:string) "hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.5"^^xsd:string) "carbon-dioxide::L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.5"^^xsd:string) "glutamine-dependent carbamoyl-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.5"^^xsd:string) "CPS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.5"^^xsd:string) "Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.5"^^xsd:string) "carbamoyl-phosphate synthase (glutamine-hydrolysing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.5"^^xsd:string) "carbamoyl phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.5"^^xsd:string) "glutamine-dependent carbamyl phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.5"^^xsd:string) "GD-CPSase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.5"^^xsd:string) "carbamoyl-phosphate synthetase (glutamine-hydrolyzing) activity"^^xsd:string) AnnotationAssertion( "carbamoyl phosphate synthase (glutamine-hydrolyzing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.5"^^xsd:string) "carbamyl phosphate synthetase (glutamine) activity"^^xsd:string) AnnotationAssertion(rdfs:label "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.5"^^xsd:string) "carbamoylphosphate synthetase II activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.1"^^xsd:string) "carbonic anhydrase A"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.1"^^xsd:string) "carbonic acid anhydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.1"^^xsd:string) "carbonate hydro-lyase (carbon-dioxide-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.1"^^xsd:string) "anhydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.1"^^xsd:string) "carbonate anhydrase activity"^^xsd:string) AnnotationAssertion(rdfs:label "carbonate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.1"^^xsd:string) "Catalysis of the reaction: H2CO3 = CO2 + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.1"^^xsd:string) "carboxyanhydrase activity"^^xsd:string) AnnotationAssertion( "carbonic anhydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.1"^^xsd:string) "carbonate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.1"^^xsd:string) "carbonic dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.184"^^xsd:string) "prostaglandin 9-ketoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.184"^^xsd:string) "carbonyl reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.184"^^xsd:string) "aldehyde reductase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.184"^^xsd:string) "secondary-alcohol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "carbonyl reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.184"^^xsd:string) "ALR3"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.184"^^xsd:string) "Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.184"^^xsd:string) "aldehyde reductase 1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.184"^^xsd:string) "xenobiotic ketone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.184"^^xsd:string) "nonspecific NADPH-dependent carbonyl reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.184"^^xsd:string) "NADPH-dependent carbonyl reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.184"^^xsd:string) "NADPH2-dependent carbonyl reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.7"^^xsd:string) "acetyl-CoA-carnitine O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.7"^^xsd:string) "carnitine acetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.7"^^xsd:string) Annotation( "RHEA:21139"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + carnitine = (R)-O-acetylcarnitine + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.7"^^xsd:string) "carnitine acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.7"^^xsd:string) "carnitine acetyl coenzyme A transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.7"^^xsd:string) "acetyl-CoA:carnitine O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.7"^^xsd:string) "CATC"^^xsd:string) AnnotationAssertion(rdfs:label "carnitine O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.7"^^xsd:string) "carnitine-acetyl-CoA transferase activity"^^xsd:string) AnnotationAssertion( "carnitine O-acetyltransferase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.7"^^xsd:string) "acetylcarnitine transferase activity"^^xsd:string) AnnotationAssertion( "carnitine O-acetyltransferase I activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.21"^^xsd:string) "carnitine palmitoyltransferase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.21"^^xsd:string) "palmitoyl-CoA:L-carnitine O-palmitoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.21"^^xsd:string) "carnitine palmitoyltransferase-A"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.21"^^xsd:string) "carnitine palmitoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.21"^^xsd:string) "carnitine palmitoyltransferase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.21"^^xsd:string) "CPTi"^^xsd:string) AnnotationAssertion(rdfs:label "carnitine O-palmitoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.21"^^xsd:string) "acylcarnitine transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.21"^^xsd:string) "CPTo"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.21"^^xsd:string) "CPT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.21"^^xsd:string) "CPT-A"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.21"^^xsd:string) "CPT-B"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.21"^^xsd:string) "CPT I (outer membrane carnitine palmitoyl transferase)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.21"^^xsd:string) "palmitoylcarnitine transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.21"^^xsd:string) "L-carnitine palmitoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.21"^^xsd:string) "outer malonyl-CoA inhibitable carnitine palmitoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.21"^^xsd:string) "Catalysis of the reaction: palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.11.1.6"^^xsd:string) "optidase activity"^^xsd:string) AnnotationAssertion( "catalase reaction"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.6"^^xsd:string) "equilase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.6"^^xsd:string) "catalase-peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.6"^^xsd:string) "Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O."^^xsd:string) AnnotationAssertion(rdfs:label "catalase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.6"^^xsd:string) "caperase activity"^^xsd:string) AnnotationAssertion( "haem catalase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.6"^^xsd:string) "CAT"^^xsd:string) AnnotationAssertion( "heme catalase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.6"^^xsd:string) "hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity"^^xsd:string) AnnotationAssertion( "manganese catalase activity"^^xsd:string) AnnotationAssertion( "bacterial catalase-peroxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.10.3.1"^^xsd:string) "Catalysis of the reaction: 2 catechol + O2 = 2 1,2-benzoquinone + 2 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.1"^^xsd:string) "catecholase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.1"^^xsd:string) "pyrocatechol oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.1"^^xsd:string) "dopa oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.1"^^xsd:string) "phenolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.1"^^xsd:string) "polyphenol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.1"^^xsd:string) "o-diphenol:oxygen oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.1"^^xsd:string) "1,2-benzenediol:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "catechol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.1"^^xsd:string) "o-diphenol oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.1"^^xsd:string) "tyrosinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.1"^^xsd:string) "o-diphenolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.1"^^xsd:string) "diphenol oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.6.8"^^xsd:string) "arylsulfatase A activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.8"^^xsd:string) "cerebroside sulfate sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.8"^^xsd:string) "cerebroside-3-sulfate 3-sulfohydrolase activity"^^xsd:string) AnnotationAssertion( "cerebroside-sulphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cerebroside-sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.8"^^xsd:string) "Catalysis of the reaction: a cerebroside 3-sulfate + H2O = a cerebroside + sulfate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.41"^^xsd:string) "Catalysis of the reaction: chitin + H2O = chitosan + acetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.41"^^xsd:string) "chitin amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "chitin deacetylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.16"^^xsd:string) "chitin-UDP N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.16"^^xsd:string) "trans-N-acetylglucosaminosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.16"^^xsd:string) "chitin-UDP acetyl-glucosaminyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.16"^^xsd:string) "UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.16"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1)."^^xsd:string) AnnotationAssertion(rdfs:label "chitin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.16"^^xsd:string) "chitin synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.16"^^xsd:string) "chitin-uridine diphosphate acetylglucosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.6"^^xsd:string) Annotation( "RHEA:18824"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + choline = acetylcholine + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.6"^^xsd:string) "choline acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "choline O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.6"^^xsd:string) "acetyl-CoA:choline O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.6"^^xsd:string) "CHOACTase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.6"^^xsd:string) "choline acetylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.32"^^xsd:string) "choline-ethanolamine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.32"^^xsd:string) Annotation( "RHEA:12840"^^xsd:string) "Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.32"^^xsd:string) "ATP:choline phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.32"^^xsd:string) "choline phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.32"^^xsd:string) "choline kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "choline kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.8"^^xsd:string) "choline esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.8"^^xsd:string) "butyrylcholine esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.8"^^xsd:string) "acylcholine acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.8"^^xsd:string) "anticholineesterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cholinesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.8"^^xsd:string) "propionylcholinesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.8"^^xsd:string) "Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.8"^^xsd:string) "benzoylcholinesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.8"^^xsd:string) "pseudocholinesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.8"^^xsd:string) "choline esterase II (unspecific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.8"^^xsd:string) "BtChoEase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.8"^^xsd:string) "non-specific cholinesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.8"^^xsd:string) "butyrylcholinesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "CTP:choline-phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.15"^^xsd:string) "CTP:phosphorylcholine cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.15"^^xsd:string) "CTP-phosphocholine cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.15"^^xsd:string) "CDP-choline pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.15"^^xsd:string) "choline phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.15"^^xsd:string) "cytidine diphosphocholine pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.15"^^xsd:string) "phosphorylcholine cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.15"^^xsd:string) "CDP-choline synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.15"^^xsd:string) "CTP:phosphocholine cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "choline-phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.15"^^xsd:string) "phosphorylcholine transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.15"^^xsd:string) "phosphocholine cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.15"^^xsd:string) "Catalysis of the reaction: CTP + choline phosphate = diphosphate + CDP-choline."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.15"^^xsd:string) "phosphorylcholine:CTP cytidylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.99.5"^^xsd:string) "hydroxyphenylpyruvate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.5"^^xsd:string) "chorismate pyruvatemutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.5"^^xsd:string) Annotation( "RHEA:13900"^^xsd:string) "Catalysis of the reaction: chorismate = prephenate."^^xsd:string) AnnotationAssertion(rdfs:label "chorismate mutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.5"^^xsd:string) "5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase (chorismate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.5"^^xsd:string) "5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.5"^^xsd:string) "5-enolpyruvylshikimate-3-phosphate phospholyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.5"^^xsd:string) Annotation( "RHEA:21023"^^xsd:string) "Catalysis of the reaction: 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "chorismate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.3.1"^^xsd:string) "citrate oxaloacetate-lyase ((pro-3S)-CH2COO-rightacetyl-CoA)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.1"^^xsd:string) "oxalacetic transacetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.1"^^xsd:string) "citrate oxaloacetate-lyase, CoA-acetylating activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.1"^^xsd:string) "oxaloacetate transacetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.1"^^xsd:string) "citrate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.1"^^xsd:string) "citric-condensing enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.1"^^xsd:string) "citrate oxaloacetate-lyase [(pro-3S)-CH2COOrightacetyl-CoA]"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.1"^^xsd:string) "citrate condensing enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.1"^^xsd:string) "citrate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.1"^^xsd:string) Annotation( "ISBN:0121227073"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.1"^^xsd:string) "citrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.1"^^xsd:string) "citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)->acetyl-CoA) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.1"^^xsd:string) "(R)-citric synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.1"^^xsd:string) "citric synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.1"^^xsd:string) "acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming]"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.1"^^xsd:string) "condensing enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "citrate (Si)-synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.3.3"^^xsd:string) "coproporphyrinogen:oxygen oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion( "coprogen oxidase activity"^^xsd:string) AnnotationAssertion( "coproporphyrinogenase activity"^^xsd:string) AnnotationAssertion( "coproporphyrinogen-III oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.3"^^xsd:string) Annotation( "RHEA:18260"^^xsd:string) "Catalysis of the reaction: coproporphyrinogen III + 2 H(+) + O(2) = 2 CO(2) + 2 H(2)O + protoporphyrinogen IX."^^xsd:string) AnnotationAssertion(rdfs:label "coproporphyrinogen oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.1.21"^^xsd:string) "11-deoxycorticosterone ketol-isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "corticosteroid side-chain-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.21"^^xsd:string) "11-deoxycorticosterone aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.21"^^xsd:string) Annotation( "RHEA:17864"^^xsd:string) "Catalysis of the reaction: 11-deoxycorticosterone = 20-hydroxy-3-oxopregn-4-en-21-al."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.3.2"^^xsd:string) "CKMiMi"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.2"^^xsd:string) "CK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.2"^^xsd:string) "phosphocreatine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.2"^^xsd:string) "CK-MM"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.2"^^xsd:string) "BB-CK"^^xsd:string) AnnotationAssertion(rdfs:label "creatine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.2"^^xsd:string) "MM-CK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.2"^^xsd:string) "creatine phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.2"^^xsd:string) "Mi-CK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.2"^^xsd:string) "ATP:creatine N-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.2"^^xsd:string) "adenosine triphosphate-creatine transphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.2"^^xsd:string) "creatine phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.2"^^xsd:string) "MB-CK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.2"^^xsd:string) "CK-BB"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.2"^^xsd:string) "ATP:creatine phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.2"^^xsd:string) Annotation( "RHEA:17160"^^xsd:string) "Catalysis of the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.2"^^xsd:string) "CK-MB"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.2"^^xsd:string) "MiMi-CK"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclic-nucleotide phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.37"^^xsd:string) "Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 2'-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.37"^^xsd:string) "CNPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.37"^^xsd:string) "2',3'-cyclic nucleotide phosphohydrolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.37"^^xsd:string) "2',3'-cyclic nucleoside monophosphate phosphodiesterase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.37"^^xsd:string) "2':3'-CNMP-3'-ase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.37"^^xsd:string) "2',3'-cyclic AMP phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.37"^^xsd:string) "2',3'-cyclic nucleotide 3'-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.37"^^xsd:string) "nucleoside-2',3'-cyclic-phosphate 2'-nucleotidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.37"^^xsd:string) "cyclic-CMP phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.37"^^xsd:string) "cyclic 2',3'-nucleotide 3'-phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.37"^^xsd:string) "2':3'-cyclic nucleotide 3'-phosphodiesterase activity"^^xsd:string) AnnotationAssertion( "2',3'-cyclic nucleotide 3'-phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.37"^^xsd:string) "cyclic 2',3'-nucleotide phosphodiesterase"^^xsd:string) AnnotationAssertion(rdfs:label "2',3'-cyclic-nucleotide 3'-phosphodiesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.17"^^xsd:string) "cyclic 3',5'-phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.17"^^xsd:string) "3',5'-cyclonucleotide phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.17"^^xsd:string) "cyclic 3',5'-mononucleotide phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.17"^^xsd:string) "3',5'-nucleotide phosphodiesterase activity"^^xsd:string) AnnotationAssertion( "3',5' cyclic-nucleotide phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.17"^^xsd:string) "cyclic AMP phosphodiesterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3',5'-cyclic-nucleotide phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.17"^^xsd:string) "Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.17"^^xsd:string) "nucleoside 3',5'-cyclic phosphate diesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.17"^^xsd:string) "3', 5'-cyclic nucleoside monophosphate phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.17"^^xsd:string) "cyclic nucleotide phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.17"^^xsd:string) "3',5'-cyclic-nucleotide 5'-nucleotidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.17"^^xsd:string) "3':5'-cyclic nucleotide 5'-nucleotidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.17"^^xsd:string) "cyclic 3',5'-nucleotide phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.17"^^xsd:string) "3': 5'-monophosphate phosphodiesterase (cyclic CMP) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.17"^^xsd:string) "nucleoside-3',5-monophosphate phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.17"^^xsd:string) "PDE"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.17"^^xsd:string) "cyclic 3',5-nucleotide monophosphate phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.17"^^xsd:string) "cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3',5' cAMP-specific phosphodiesterase activity"^^xsd:string) AnnotationAssertion( "3',5'-cyclic-AMP-specific phosphodiesterase activity"^^xsd:string) AnnotationAssertion( "3',5'-cAMP-specific phosphodiesterase activity"^^xsd:string) AnnotationAssertion( "cAMP-specific phosphodiesterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3',5'-cyclic-AMP phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: adenosine 3',5'-cyclic phosphate + H2O = adenosine 5'-phosphate."^^xsd:string) AnnotationAssertion( "cyclic AMP-specific phosphodiesterase activity"^^xsd:string) AnnotationAssertion( "adenosine 3',5'-cyclophosphate-specific phosphodiesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is regulated by calmodulin."^^xsd:string) AnnotationAssertion(rdfs:label "calmodulin-dependent cyclic-nucleotide phosphodiesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cGMP-stimulated cyclic-nucleotide phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is increased in the presence of cGMP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cGMP-inhibited cyclic-nucleotide phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is decreased in the presence of cGMP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.-"^^xsd:string) "Catalysis of the reaction: nucleoside cyclic phosphate + H2O = nucleoside phosphate. This reaction is the hydrolysis of bonds in a cyclic nucleotide."^^xsd:string) AnnotationAssertion(rdfs:label "photoreceptor cyclic-nucleotide phosphodiesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.8"^^xsd:string) "L-cystathionine L-homocysteine-lyase (deaminating; pyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.8"^^xsd:string) "Catalysis of the reaction: cystathionine + H2O = L-homocysteine + NH3 + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.8"^^xsd:string) "beta-cystathionase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.8"^^xsd:string) "L-cystathionine L-homocysteine-lyase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.8"^^xsd:string) "cystine lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cystathionine beta-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.8"^^xsd:string) "cystathionine L-homocysteine-lyase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.8"^^xsd:string) "beta C-S lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.22"^^xsd:string) "Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.22"^^xsd:string) "L-serine hydro-lyase (adding homocysteine)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.22"^^xsd:string) "serine sulfhydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.22"^^xsd:string) "beta-thionase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.22"^^xsd:string) "L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.22"^^xsd:string) "methylcysteine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.22"^^xsd:string) "serine sulfhydrylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cystathionine beta-synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.1"^^xsd:string) "L-cystathionine cysteine-lyase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.1"^^xsd:string) "L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.1"^^xsd:string) "homoserine dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.1"^^xsd:string) "homoserine deaminase-cystathionase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cystathionine gamma-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.1"^^xsd:string) "homoserine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:24918"^^xsd:string) "Catalysis of the reaction: L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4+."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.1"^^xsd:string) "gamma-cystathionase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.47"^^xsd:string) "cysteine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.47"^^xsd:string) "O-acetylserine (thiol)-lyase A activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.47"^^xsd:string) "O-acetylserine sulfhydrylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.47"^^xsd:string) "O-acetyl-L-serine sulfohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.47"^^xsd:string) "OAS sulfhydrylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.47"^^xsd:string) "3-O-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.47"^^xsd:string) "acetylserine sulfhydrylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.47"^^xsd:string) "O3-acetyl-L-serine acetate-lyase (adding hydrogen-sulfide)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.47"^^xsd:string) "O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.8"^^xsd:string) "Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.47"^^xsd:string) "O-acetylserine (thiol)-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cysteine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.47"^^xsd:string) "O(3)-acetyl-L-serine acetate-lyase (adding hydrogen-sulfide) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.47"^^xsd:string) "O-acetyl-L-serine sulfhydrylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.9.1.1"^^xsd:string) "L-selenocysteinyl-tRNASel synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.9.1.1"^^xsd:string) "cysteinyl-tRNASec-selenium transferase activity"^^xsd:string) AnnotationAssertion( "cysteinyl-tRNA(Ser) selenium transferase activity"^^xsd:string) AnnotationAssertion( "selenocysteinyl-tRNA(Ser) synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.9.1.1"^^xsd:string) "cysteinyl-tRNA(Sel)-selenium transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.9.1.1"^^xsd:string) "cysteinyl-tRNA(Sec)-selenium transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.9.1.1"^^xsd:string) "L-selenocysteinyl-tRNA(Sel) synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.9.1.1"^^xsd:string) "L-selenocysteinyl-tRNA(Sec) synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.9.1.1"^^xsd:string) "selenophosphate:L-seryl-tRNASec selenium transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-seryl-tRNASec selenium transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.9.1.1"^^xsd:string) "L-selenocysteinyl-tRNASec synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.9.1.1"^^xsd:string) "cysteinyl-tRNASel-selenium transferase activity"^^xsd:string) AnnotationAssertion( "selenocysteine synthase activity"^^xsd:string) AnnotationAssertion( "L-seryl-tRNA(Ser) selenium transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.9.1.1"^^xsd:string) "Catalysis of the reaction: L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + H2O + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.5"^^xsd:string) "cytidine aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.5"^^xsd:string) "cytosine nucleoside deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.5"^^xsd:string) "Catalysis of the reaction: cytidine + H2O = uridine + NH3."^^xsd:string) AnnotationAssertion(rdfs:label "cytidine deaminase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.4.14"^^xsd:string) "CTP:CMP phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.14"^^xsd:string) "ATP:UMP-CMP phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.14"^^xsd:string) "ATP:CMP phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.14"^^xsd:string) "deoxycytidylate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.14"^^xsd:string) "Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP."^^xsd:string) AnnotationAssertion(rdfs:label "cytidylate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.14"^^xsd:string) "deoxycytidine monophosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.14"^^xsd:string) "dCMP kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.14"^^xsd:string) "CMP kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.14"^^xsd:string) "cytidine monophosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.14"^^xsd:string) "pyrimidine nucleoside monophosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.14"^^xsd:string) "UMP-CMP kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.6.2.2"^^xsd:string) "NADH:ferricytochrome-b5 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.2"^^xsd:string) "NADH 5alpha-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.2"^^xsd:string) "NADH-cytochrome b5 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.2"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the reaction: NAD(P)H + H+ + 2 ferricytochrome b(5) = NAD(P)+ + 2 ferrocytochrome b(5)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.2"^^xsd:string) "NADH-cytochrome-b5 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.2"^^xsd:string) "dihydronicotinamide adenine dinucleotide-cytochrome b5 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.2"^^xsd:string) "cytochrome b5 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.2"^^xsd:string) "NADH-ferricytochrome b5 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.2"^^xsd:string) "reduced nicotinamide adeninedinucleotide-cytochrome b5 reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cytochrome-b5 reductase activity, acting on NAD(P)H"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cytochrome-c oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.3.1"^^xsd:string) "ferrocytochrome c oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.3.1"^^xsd:string) "indophenolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.3.1"^^xsd:string) "cytochrome a3 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.3.1"^^xsd:string) "warburg's respiratory enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.3.1"^^xsd:string) "NADH cytochrome c oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.3.1"^^xsd:string) "cytochrome aa3 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.3.1"^^xsd:string) "aa3-type cytochrome c oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.3.1"^^xsd:string) "ferrocytochrome-c:oxygen oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.3.1"^^xsd:string) "caa3-type cytochrome c oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.3.1"^^xsd:string) "ba3-type cytochrome c oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.3.1"^^xsd:string) "complex IV (mitochondrial electron transport) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.3.1"^^xsd:string) "Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.3.1"^^xsd:string) "indophenol oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.3.1"^^xsd:string) "cbb3-type cytochrome c oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.3.1"^^xsd:string) "cytochrome oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "cytochrome c oxidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.11.1.5"^^xsd:string) "cytochrome c-H2O oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.5"^^xsd:string) "cytochrome peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.5"^^xsd:string) "Catalysis of the reaction: 2 ferrocytochrome c + hydrogen peroxide = 2 ferricytochrome c + 2 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.5"^^xsd:string) "mesocytochrome c peroxidase azide"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.5"^^xsd:string) "cytochrome c-551 peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.5"^^xsd:string) "cytochrome c peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.5"^^xsd:string) "mesocytochrome c peroxidase cyanate"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.5"^^xsd:string) "mesocytochrome c peroxidase cyanide"^^xsd:string) AnnotationAssertion(rdfs:label "cytochrome-c peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.5"^^xsd:string) "apocytochrome c peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.5"^^xsd:string) "ferrocytochrome-c:hydrogen-peroxide oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cytosine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.1"^^xsd:string) "cytosine aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.1"^^xsd:string) "Catalysis of the reaction: cytosine + H2O = uracil + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.1"^^xsd:string) "isocytosine deaminase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.12"^^xsd:string) "dCMP aminohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dCMP deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.12"^^xsd:string) "deoxycytidylate aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.12"^^xsd:string) "deoxycytidine-5'-monophosphate aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.12"^^xsd:string) "deoxycytidine-5'-phosphate deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.12"^^xsd:string) "Catalysis of the reaction: dCMP + H2O = dUMP + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.12"^^xsd:string) "deoxy-CMP-deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.12"^^xsd:string) "deoxycytidine monophosphate deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.12"^^xsd:string) "deoxycytidylate deaminase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycogen debranching enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the cleavage of branch points in branched glycogen polymers."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.25"^^xsd:string) "D-enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.25"^^xsd:string) "oligo-1,4-1,4-glucantransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.25"^^xsd:string) "Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan."^^xsd:string) AnnotationAssertion(rdfs:label "4-alpha-glucanotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.25"^^xsd:string) "dextrin glycosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.25"^^xsd:string) "disproportionating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.25"^^xsd:string) "debranching enzyme maltodextrin glycosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.25"^^xsd:string) "amylomaltase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.25"^^xsd:string) "1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.25"^^xsd:string) "dextrin transglycosylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.33"^^xsd:string) "dextrin-1,6-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.33"^^xsd:string) "dextrin 6-alpha-D-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.33"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the (1->6) glycosidic linkages present."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.33"^^xsd:string) "amylopectin 1,6-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.33"^^xsd:string) "glycogen phosphorylase-limit dextrin alpha-1,6-glucohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "amylo-alpha-1,6-glucosidase activity"^^xsd:string) AnnotationAssertion( "amylo-1,6-glucosidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.76"^^xsd:string) "deoxyadenosine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.76"^^xsd:string) "purine-deoxyribonucleoside kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.76"^^xsd:string) Annotation( "RHEA:23455"^^xsd:string) "Catalysis of the reaction: 2'-deoxyadenosine + ATP = ADP + dAMP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.76"^^xsd:string) "ATP:deoxyadenosine 5'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "deoxyadenosine kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.74"^^xsd:string) "deoxycytidine-cytidine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.74"^^xsd:string) "Ara-C kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.74"^^xsd:string) "arabinofuranosylcytosine kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "deoxycytidine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.74"^^xsd:string) "2'-deoxycytidine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.74"^^xsd:string) "deoxycytidine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.74"^^xsd:string) "Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.74"^^xsd:string) "NTP:deoxycytidine 5'-phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "deoxyguanosine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.113"^^xsd:string) "NTP-deoxyguanosine 5'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.113"^^xsd:string) "ATP:deoxyguanosine 5'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.113"^^xsd:string) "2'-deoxyguanosine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.113"^^xsd:string) "deoxyguanosine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.113"^^xsd:string) Annotation( "RHEA:19204"^^xsd:string) "Catalysis of the reaction: 2'-deoxyguanosine + ATP = ADP + dGMP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.113"^^xsd:string) "(dihydroxypropoxymethyl)guanine kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "deoxyribose-phosphate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.4"^^xsd:string) "phosphodeoxyriboaldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.4"^^xsd:string) "deoxyribose-5-phosphate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.4"^^xsd:string) "2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.4"^^xsd:string) Annotation( "RHEA:12824"^^xsd:string) "Catalysis of the reaction: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.4"^^xsd:string) "2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.4"^^xsd:string) "deoxyriboaldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.4"^^xsd:string) "2-deoxyribose-5-phosphate aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.24"^^xsd:string) "ATP:dephospho-CoA 3'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.24"^^xsd:string) Annotation( "RHEA:18248"^^xsd:string) "Catalysis of the reaction: 3'-dephospho-CoA + ATP = ADP + CoA + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.24"^^xsd:string) "3'-dephospho-CoA kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.24"^^xsd:string) "dephosphocoenzyme A kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.24"^^xsd:string) "dephosphocoenzyme A kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dephospho-CoA kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.3.3"^^xsd:string) Annotation( "RHEA:15808"^^xsd:string) "Catalysis of the reaction: 7,8-diaminononanoate + ATP + CO(2) = ADP + dethiobiotin + 4 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.3"^^xsd:string) "desthiobiotin synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dethiobiotin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.3"^^xsd:string) "7,8-diaminononanoate:carbon-dioxide cyclo-ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.3"^^xsd:string) "DTB synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.2"^^xsd:string) "sn-1,2-diacylglycerol cholinephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.2"^^xsd:string) "phosphorylcholine--glyceride transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.2"^^xsd:string) "cytidine diphosphorylcholine diglyceride transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.2"^^xsd:string) "cholinephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.2"^^xsd:string) "cytidine diphosphocholine glyceride transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.2"^^xsd:string) "1-alkyl-2-acetyl-sn-glycerol cholinephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.2"^^xsd:string) "1-alkyl-2-acetyl-m-glycerol:CDPcholine choline phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.2"^^xsd:string) "CDP-choline diglyceride phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.2"^^xsd:string) "alkylacylglycerol cholinephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.2"^^xsd:string) "CDP-choline:1,2-diacylglycerol cholinephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.2"^^xsd:string) "phosphocholine diacylglyceroltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.2"^^xsd:string) "alkylacylglycerol choline phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.2"^^xsd:string) "Catalysis of the reaction: CDP-choline + 1,2-diacylglycerol = CMP + a phosphatidylcholine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.2"^^xsd:string) "1-alkyl-2-acetylglycerol cholinephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.2"^^xsd:string) "CPT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.2"^^xsd:string) "diacylglycerol choline phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "diacylglycerol cholinephosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.107"^^xsd:string) "DGK activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.107"^^xsd:string) "arachidonoyl-specific diacylglycerol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.107"^^xsd:string) "diglyceride kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.107"^^xsd:string) "1,2-diacylglycerol kinase activity"^^xsd:string) AnnotationAssertion( "CTP:diacylglycerol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.107"^^xsd:string) "ATP:diacylglycerol phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.107"^^xsd:string) "1,2-diacylglycerol kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.107"^^xsd:string) Annotation( "GOC:elh"^^xsd:string) "Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol-3-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.107"^^xsd:string) "diacylglycerol:ATP kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.107"^^xsd:string) "sn-1,2-diacylglycerol kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "diacylglycerol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.107"^^xsd:string) "DG kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.107"^^xsd:string) "ATP:1,2-diacylglycerol 3-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "diacylglycerol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.20"^^xsd:string) "Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.20"^^xsd:string) "palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.20"^^xsd:string) "diglyceride O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.20"^^xsd:string) "1,2-diacylglycerol acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.20"^^xsd:string) "acyl-CoA:1,2-diacylglycerol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.20"^^xsd:string) "diacylglycerol acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.20"^^xsd:string) "diglyceride acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "spermine N(1)-acetyltransferase"^^xsd:string) AnnotationAssertion( "diamine acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.57"^^xsd:string) "putrescine acetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.57"^^xsd:string) "spermidine N(1)-acetyltransferase activity"^^xsd:string) AnnotationAssertion( "spermine N-acetyltransferase"^^xsd:string) AnnotationAssertion( "acetyl-coenzyme A-1,4-diaminobutane N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.57"^^xsd:string) "spermidine/spermine N1-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.57"^^xsd:string) "acetyl-CoA:alkane-alpha,omega-diamine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.57"^^xsd:string) "spermidine N1-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.57"^^xsd:string) "putrescine acetyltransferase activity"^^xsd:string) AnnotationAssertion( "putrescine (diamine)-acetylating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.57"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine."^^xsd:string) AnnotationAssertion( "spermine acetyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.57"^^xsd:string) "putrescine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.57"^^xsd:string) "spermidine acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "diamine N-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "dihydrofolate reduction"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.3"^^xsd:string) "dihydrofolic acid reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dihydrofolate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.3"^^xsd:string) "5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.3"^^xsd:string) "Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.3"^^xsd:string) "pteridine reductase:dihydrofolate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.3"^^xsd:string) "dihydrofolate reductase:thymidylate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.3"^^xsd:string) "7,8-dihydrofolate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.3"^^xsd:string) "tetrahydrofolate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.3"^^xsd:string) "folic acid reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.3"^^xsd:string) "dihydrofolic reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.3"^^xsd:string) "NADPH-dihydrofolate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.3"^^xsd:string) "thymidylate synthetase-dihydrofolate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.3"^^xsd:string) "DHFR"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.3"^^xsd:string) "folic reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dihydrolipoamide branched chain acyltransferase activity"^^xsd:string) AnnotationAssertion( "dihydrolipoamide branched chain transacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: acyl-CoA + dihydrolipoamide = CoA + S-acyldihydrolipoamide, where the acyl group is a branched chain."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "dihydrolipoamide dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "dihydrolipoylprotein reduction"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "dihydrolipoic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "LDP-Glc activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "E3 component of alpha-ketoacid dehydrogenase complexes activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "protein-N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "dihydrothioctic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "dehydrolipoate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dihydrolipoyl dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "lipoate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "lipoyl dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "LDP-Val activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "lipoic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "Catalysis of the reaction: protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "protein-6-N-(dihydrolipoyl)lysine:NAD+ oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "lipoamide dehydrogenase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "diaphorase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "dihydrolipoamide reduction"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "lipoamide oxidoreductase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "glycine-cleavage system L-protein activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "L-protein activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "dihydrolipoamide:NAD+ oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "lipoamide reductase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.4"^^xsd:string) "lipoamide reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.61"^^xsd:string) "lipoyl transsuccinylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.61"^^xsd:string) "dihydrolipoyl transsuccinylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.61"^^xsd:string) "succinyl-CoA:dihydrolipoamide S-succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.61"^^xsd:string) "lipoic transsuccinylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.61"^^xsd:string) "enzyme-dihydrolipoyllysine:succinyl-CoA S-succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.61"^^xsd:string) "succinyl-CoA:dihydrolipoate S-succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.61"^^xsd:string) "dihydrolipoamide succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.61"^^xsd:string) "lipoate succinyltransferase (Escherichia coli) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.61"^^xsd:string) "succinyl-CoA:enzyme-N6-(dihydrolipoyl)lysine S-succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.61"^^xsd:string) "succinyl-CoA:enzyme-6-N-(dihydrolipoyl)lysine S-succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.61"^^xsd:string) "dihydrolipolyl transsuccinylase activity"^^xsd:string) AnnotationAssertion( "dihydrolipoamide S-succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.61"^^xsd:string) "Catalysis of the reaction: succinyl-CoA + dihydrolipoamide = CoA + S-succinyldihydrolipoamide."^^xsd:string) AnnotationAssertion(rdfs:label "dihydrolipoyllysine-residue succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.61"^^xsd:string) "dihydrolipoic transsuccinylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.61"^^xsd:string) "lipoate succinyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dihydroneopterin aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.25"^^xsd:string) "2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine glycolaldehyde-lyase (2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.25"^^xsd:string) "Catalysis of the reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.25"^^xsd:string) "2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine glycolaldehyde-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.2.3"^^xsd:string) "(S)-dihydroorotate amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.3"^^xsd:string) "dihydroorotate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.3"^^xsd:string) "DHOase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.3"^^xsd:string) Annotation( "RHEA:24299"^^xsd:string) "Catalysis of the reaction: (S)-dihydroorotate + H(2)O = N-carbamoyl-L-aspartate + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "dihydroorotase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.3"^^xsd:string) "carbamoylaspartic dehydrase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.5.2"^^xsd:string) Annotation( "RHEA:18076"^^xsd:string) "Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate."^^xsd:string) AnnotationAssertion(rdfs:label "dihydroorotate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.5.2"^^xsd:string) "dihydroorotate:ubiquinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.5.2"^^xsd:string) "(DHO) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.5.2"^^xsd:string) Annotation( ) "(S)-dihydroorotate:quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.5.2"^^xsd:string) "dihydoorotic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.5.2"^^xsd:string) "DHOdehase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "FB:FBrf0039640"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) Annotation( "ISSN:05829879"^^xsd:string) Annotation( "http://www.abbs.info/fulltxt/eng/35030306.htm"^^xsd:string) "Catalysis of the reaction: 7,8-dihydropterin + H2O = 7,8-dihydrolumazine + NH3."^^xsd:string) AnnotationAssertion(rdfs:label "dihydropterin deaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:1745247"^^xsd:string) Annotation( "PMID:6815189"^^xsd:string) "Catalysis of the reaction: a 7,8-dihydropteridine + O2 = a pterin + hydrogen peroxide."^^xsd:string) AnnotationAssertion(rdfs:label "dihydropterin oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.34"^^xsd:string) "6,7-dihydropteridine:NAD(P)H oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.34"^^xsd:string) "dihydropteridine (reduced nicotinamide adenine dinucleotide) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.34"^^xsd:string) "NAD(P)H2:6,7-dihydropteridine oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.34"^^xsd:string) "NADH-dihydropteridine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.34"^^xsd:string) "5,6,7,8-tetrahydropteridine:NAD(P)H+ oxidoreductase activity"^^xsd:string) AnnotationAssertion( "dihydropteridine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.34"^^xsd:string) "Catalysis of the reaction: NADP+ + 5,6,7,8-tetrahydropteridine = NADPH + H+ + 6,7-dihydropteridine."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.34"^^xsd:string) "NADPH-specific dihydropteridine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.34"^^xsd:string) "5,6,7,8-tetrahydropteridine:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "6,7-dihydropteridine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.34"^^xsd:string) "NAD(P)H(2):6,7-dihydropteridine oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.34"^^xsd:string) "NADPH-dihydropteridine reductase activity"^^xsd:string) AnnotationAssertion( "dihydropteridine reduction"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.34"^^xsd:string) "DHPR activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.34"^^xsd:string) "dihydropteridine reductase (NADH) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.15"^^xsd:string) "dihydropteroate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.15"^^xsd:string) "dihydropteroic synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.15"^^xsd:string) "dihydropteroate diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.15"^^xsd:string) "7,8-dihydropteroic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.15"^^xsd:string) "dihydropteroate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.15"^^xsd:string) "Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate = diphosphate + dihydropteroate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.15"^^xsd:string) "2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.15"^^xsd:string) "DHPS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.15"^^xsd:string) "(2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.15"^^xsd:string) "7,8-dihydropteroate synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dihydropteroate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.15"^^xsd:string) "7,8-dihydropteroate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dihydropyrimidinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.2"^^xsd:string) "hydantoin peptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.2"^^xsd:string) "hydropyrimidine hydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.2"^^xsd:string) "D-hydantoinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.2"^^xsd:string) "pyrimidine hydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.2"^^xsd:string) "Catalysis of the reaction: 5,6-dihydrouracil + H2O = 3-ureidopropionate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.2"^^xsd:string) "hydantoinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.2"^^xsd:string) "5,6-dihydropyrimidine amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dihydroorotate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.1"^^xsd:string) Annotation( "RHEA:15444"^^xsd:string) "Catalysis of the reaction: (S)-dihydroorotate + O(2) = H(2)O(2) + orotate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.1"^^xsd:string) "(S)-dihydroorotate:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.1"^^xsd:string) "4,5-L-dihydroorotate:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.1"^^xsd:string) "5,6-dihydrouracil:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.1"^^xsd:string) "Catalysis of the reaction: 5,6-dihydrouracil + NAD+ = uracil + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.1"^^xsd:string) "uracil reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.1"^^xsd:string) "pyrimidine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.1"^^xsd:string) "thymine reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dihydrouracil dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.1"^^xsd:string) "dehydrogenase, dihydrouracil"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.9"^^xsd:string) "2,3-dihydroxy-acid hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.9"^^xsd:string) "alpha,beta-dihydroxyisovalerate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.9"^^xsd:string) "alpha,beta-dihydroxyacid dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.9"^^xsd:string) "2,3-dihydroxyisovalerate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.9"^^xsd:string) "acetohydroxyacid dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.9"^^xsd:string) "dihydroxy acid dehydrase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dihydroxy-acid dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.9"^^xsd:string) "2,3-dihydroxy-acid hydro-lyase (3-methyl-2-oxobutanoate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.9"^^xsd:string) "Catalysis of the reaction: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.9"^^xsd:string) "DHAD"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.1"^^xsd:string) "diprenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.1"^^xsd:string) "geranyl pyrophosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.1"^^xsd:string) "geranyl pyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.1"^^xsd:string) "dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.1"^^xsd:string) "trans-farnesyl pyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.1"^^xsd:string) "(2E,6E)-farnesyl diphosphate synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dimethylallyltranstransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.1"^^xsd:string) "geranyl-diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.1"^^xsd:string) "DMAPP:IPP-dimethylallyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.1"^^xsd:string) "Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate."^^xsd:string) AnnotationAssertion( "dimethylallyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "N-nitrosodimethylamine demethylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dimethylnitrosamine demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the removal of a methyl group from N-nitrosodimethylamine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.33"^^xsd:string) "mevalonate-5-pyrophosphate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.33"^^xsd:string) "pyrophosphomevalonic acid decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.33"^^xsd:string) "mevalonate 5-diphosphate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.33"^^xsd:string) "pyrophosphomevalonate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.33"^^xsd:string) Annotation( "RHEA:23735"^^xsd:string) "Catalysis of the reaction: (R)-5-diphosphomevalonate + ATP = ADP + CO(2) + H(+) + isopentenyl diphosphate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.33"^^xsd:string) "mevalonate diphosphate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.33"^^xsd:string) "mevalonate pyrophosphate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.33"^^xsd:string) "ATP:(R)-5-diphosphomevalonate carboxy-lyase (adding ATP; isopentenyl-diphosphate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.33"^^xsd:string) "5-pyrophosphomevalonate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.33"^^xsd:string) "ATP:(R)-5-diphosphomevalonate carboxy-lyase (dehydrating)"^^xsd:string) AnnotationAssertion(rdfs:label "diphosphomevalonate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.98"^^xsd:string) "S-adenosyl-L-methionine:elongation factor 2 methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "diphthine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.98"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine = S-adenosyl-L-homocysteine + 2-(3-carboxy-3-(methylammonio)propyl)-L-histidine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.98"^^xsd:string) "diphthine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.98"^^xsd:string) "S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.3.8"^^xsd:string) "delta3-cis-delta2-trans-enoyl-CoA isomerase"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.8"^^xsd:string) "acetylene-allene isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.8"^^xsd:string) "delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.8"^^xsd:string) "delta3,Delta2-enoyl-CoA isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.8"^^xsd:string) "3,2-trans-enoyl-CoA isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.8"^^xsd:string) "dodecenoyl-CoA delta3-cis-delta2-trans-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.8"^^xsd:string) "dodecenoyl-CoA Delta-isomerase activity"^^xsd:string) AnnotationAssertion( "dodecenoyl-CoA D-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.8"^^xsd:string) "Catalysis of the reaction: 3-cis-dodecenoyl-CoA = 2-trans-dodecenoyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.8"^^xsd:string) "dodecenoyl-CoA (3Z)-(2E)-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.8"^^xsd:string) "delta(3),Delta(2)-enoyl-CoA isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dodecenoyl-CoA delta-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.8"^^xsd:string) "dodecenoyl-CoA isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.153"^^xsd:string) "UDP-N-acetylglucosamine-dolichol phosphate N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.153"^^xsd:string) "dolichyl-phosphate N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.153"^^xsd:string) "dolichyl phosphate N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.153"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.153"^^xsd:string) "uridine diphosphoacetylglucosamine-dolichol phosphate acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.153"^^xsd:string) "UDP-N-acetyl-D-glucosamine:dolichyl-phosphate alpha-N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.153"^^xsd:string) "dolichyl-phosphate acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.153"^^xsd:string) "dolichyl phosphate acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dolichyl-phosphate alpha-N-acetylglucosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "TRP-2"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "dopachrome delta7,Delta2-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "DCT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "dopachrome conversion factor activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "TRP activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "dopachrome-rearranging enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) Annotation( "RHEA:13044"^^xsd:string) "Catalysis of the reaction: L-dopachrome = 5,6-dihydroxyindole-2-carboxylate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "L-dopachrome-methyl ester tautomerase activity"^^xsd:string) AnnotationAssertion( "dopachrome delta-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "dopachrome rearranging enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "tyrosinase-related protein 2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "L-dopachrome keto-enol isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "L-dopachrome isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "TRP2"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "TRP-1"^^xsd:string) AnnotationAssertion(rdfs:label "dopachrome isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "dopachrome Delta(7),Delta(2)-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "tryosinase-related protein-2"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "dopachrome oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "dopachrome keto-enol isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "dopachrome tautomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.12"^^xsd:string) "DCF activity"^^xsd:string) AnnotationAssertion( "dopachrome conversion activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.108"^^xsd:string) "dolichol phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.108"^^xsd:string) "CTP:dolichol O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dolichol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.108"^^xsd:string) "Catalysis of the reaction: CTP + dolichol = CDP + dolichyl phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.109"^^xsd:string) "dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase activity"^^xsd:string) AnnotationAssertion( "dolichyl-phosphate-mannose-protein O-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.109"^^xsd:string) "protein O-D-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dolichyl-phosphate-mannose-protein mannosyltransferase activity"^^xsd:string) AnnotationAssertion( "protein O-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.109"^^xsd:string) "Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein."^^xsd:string) AnnotationAssertion( "O-glycoside mannosyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.109"^^xsd:string) "dolichol phosphomannose-protein mannosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.23"^^xsd:string) "Catalysis of the reaction: dUTP + H2O = dUMP + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.23"^^xsd:string) "deoxyuridine-triphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.23"^^xsd:string) "desoxyuridine 5'-triphosphate nucleotidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.23"^^xsd:string) "dUTP nucleotidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.23"^^xsd:string) "dUTPase activity"^^xsd:string) AnnotationAssertion( "dUTP pyrophosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dUTP diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.23"^^xsd:string) "desoxyuridine 5'-triphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.139"^^xsd:string) "palmitoyl-CoA:ecdysone palmitoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.139"^^xsd:string) "fatty acyl-CoA:ecdysone acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.139"^^xsd:string) Annotation( "RHEA:15220"^^xsd:string) "Catalysis of the reaction: Ecdysone + palmitoyl-CoA = CoA + ecdysone palmitate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.139"^^xsd:string) "acyl-CoA:ecdysone acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ecdysone O-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.5.1"^^xsd:string) "ETF-QO activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.5.1"^^xsd:string) "electron transfer flavoprotein-ubiquinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.5.1"^^xsd:string) "electron-transferring-flavoprotein:ubiquinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.5.1"^^xsd:string) "ETF-ubiquinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.5.1"^^xsd:string) "electron transfer flavoprotein Q oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.5.1"^^xsd:string) "electron transfer flavoprotein reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.5.1"^^xsd:string) "ETF:ubiquinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.5.1"^^xsd:string) "electron transfer flavoprotein dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "electron-transferring-flavoprotein dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.5.1"^^xsd:string) "Catalysis of the reaction: reduced ETF + ubiquinone = ETF + ubiquinol."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.5.1"^^xsd:string) "ETF dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#ENDOPEPTIDASE"^^xsd:string) "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain."^^xsd:string) AnnotationAssertion(rdfs:label "endopeptidase activity"^^xsd:string) AnnotationAssertion( "proteinase"^^xsd:string) AnnotationAssertion( "proteasome endopeptidase activity"^^xsd:string) AnnotationAssertion( "endoprotease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "elastase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ATP-dependent peptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "ATP-dependent proteolysis"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the hydrolysis of peptide bonds."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aminopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the hydrolysis of N-terminal amino acid residues from in a polypeptide chain."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carboxypeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the hydrolysis of the terminal or penultimate peptide bond at the C-terminal end of a peptide or polypeptide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "metallocarboxypeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CARBOXYPEPTIDASE"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) "Catalysis of the hydrolysis of C-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0716720094"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CARBOXYPEPTIDASE"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) "Catalysis of the hydrolysis of a peptide bond not more than three residues from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)."^^xsd:string) AnnotationAssertion( "serine carboxypeptidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "serine-type carboxypeptidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "aspartic protease activity"^^xsd:string) AnnotationAssertion(rdfs:label "aspartic-type endopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "aspartate protease activity"^^xsd:string) AnnotationAssertion( "aspartic endopeptidase activity"^^xsd:string) AnnotationAssertion( "carboxyl protease activity"^^xsd:string) AnnotationAssertion( "aspartyl protease activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_apoptosis"^^xsd:string) "caspase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#ENDOPEPTIDASE"^^xsd:string) "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile."^^xsd:string) AnnotationAssertion( "thiol endopeptidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cysteine-type endopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_apoptosis"^^xsd:string) "metacaspase activity"^^xsd:string) AnnotationAssertion( "lysosomal cysteine-type endopeptidase"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcium-dependent cysteine-type endopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium."^^xsd:string) AnnotationAssertion( "calpain activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ubiquitinyl hydrolase 1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.15"^^xsd:string) "ubiquitin thioesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.15"^^xsd:string) "ubiquitin-C-terminal-thioester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.15"^^xsd:string) Annotation( "GOC:jh2"^^xsd:string) "Catalysis of the reaction: ubiquitin C-terminal thioester + H2O = ubiquitin + a thiol."^^xsd:string) AnnotationAssertion( "ubiquitin C-terminal hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.15"^^xsd:string) "ubiquitin carboxy-terminal hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ubiquitin thiolesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.15"^^xsd:string) "ubiquitin carboxy-terminal esterase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#ENDOPEPTIDASE"^^xsd:string) "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "metalloendoproteinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "metalloendopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "metalloendoprotease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "serine-type endopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0716720094"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)."^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "serine elastase activity"^^xsd:string) AnnotationAssertion( "blood coagulation factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.4.25"^^xsd:string) "tricorn proteinase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.25"^^xsd:string) "multicatalytic endopeptidase complex"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.25"^^xsd:string) "26S protease"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.25"^^xsd:string) "alkaline protease"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.25"^^xsd:string) "tricorn protease"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.25"^^xsd:string) "multicatalytic proteinase (complex)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.25"^^xsd:string) "prosome"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.25"^^xsd:string) "ingensin"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.25"^^xsd:string) "MCP"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.25"^^xsd:string) "lens neutral proteinase"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#ENDOPEPTIDASE"^^xsd:string) "Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile."^^xsd:string) AnnotationAssertion( "threonine endopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.25"^^xsd:string) "large multicatalytic protease"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.25"^^xsd:string) "multicatalytic proteinase"^^xsd:string) AnnotationAssertion(rdfs:label "threonine-type endopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.25"^^xsd:string) "proteasome endopeptidase complex"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "short chain enoyl coenzyme A hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "D-3-hydroxyacyl-CoA dehydratase"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "enoyl coenzyme A hydrase (D)"^^xsd:string) AnnotationAssertion( "short-chain enoyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "2-enoyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "2-octenoyl coenzyme A hydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "enoyl hydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "enoyl coenzyme A hydrase (L)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "acyl coenzyme A hydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "hydratase, enoyl coenzyme A"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "trans-2-enoyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "beta-hydroxyacyl-CoA dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "beta-hydroxyacid dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "ECH"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "enoyl coenzyme A hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2-enoyl-CoA + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "(3S)-3-hydroxyacyl-CoA hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "crotonyl hydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "unsaturated acyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "enoyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.17"^^xsd:string) "enol-CoA hydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.3.2.10"^^xsd:string) "aryl epoxide hydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.10"^^xsd:string) "cytosolic epoxide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.10"^^xsd:string) "arene-oxide hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.10"^^xsd:string) "soluble epoxide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.10"^^xsd:string) "sEH"^^xsd:string) AnnotationAssertion(rdfs:label "epoxide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.10"^^xsd:string) "Catalysis of the reaction: an epoxide + H2O = a glycol."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.10"^^xsd:string) "epoxide hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.10"^^xsd:string) "epoxide hydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.10"^^xsd:string) "trans-stilbene oxide hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.62"^^xsd:string) "17beta,20alpha-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.62"^^xsd:string) "20alpha-hydroxysteroid dehydrogenase"^^xsd:string) AnnotationAssertion(rdfs:label "estradiol 17-beta-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.62"^^xsd:string) "17-beta-HSD activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.62"^^xsd:string) "17beta-HSD"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.62"^^xsd:string) "estradiol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.62"^^xsd:string) "17beta-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.62"^^xsd:string) "estradiol-17beta:NAD(P)+ 17-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.62"^^xsd:string) "17beta-estradiol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.62"^^xsd:string) "17-beta-estradiol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.62"^^xsd:string) "17-beta-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.62"^^xsd:string) "Catalysis of the reaction: estradiol-17-beta + NADP+ = estrone + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.62"^^xsd:string) "estrogen 17-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.62"^^xsd:string) "estradiol 17beta-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.4"^^xsd:string) "estrogen sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.4"^^xsd:string) "3'-phosphoadenylyl-sulfate:estrone 3-sulfotransferase activity"^^xsd:string) AnnotationAssertion( "estrone sulphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "estrone sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.4"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.4"^^xsd:string) "oestrogen sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.4"^^xsd:string) "estrogen sulfotransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.4"^^xsd:string) "3'-phosphoadenylylsulfate:oestrone sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.4"^^xsd:string) "3'-phosphoadenylyl sulfate-estrone 3-sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.82"^^xsd:string) "ethanolamine phosphokinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ethanolamine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.82"^^xsd:string) "ethanolamine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.82"^^xsd:string) "ATP:ethanolamine O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.82"^^xsd:string) Annotation( "RHEA:13072"^^xsd:string) "Catalysis of the reaction: ATP + ethanolamine = ADP + 2 H(+) + phosphoethanolamine."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "CTP:ethanolamine-phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.14"^^xsd:string) "CTP:phosphoethanolamine cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ethanolamine-phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.14"^^xsd:string) "CTP-phosphoethanolamine cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.14"^^xsd:string) "ET"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.14"^^xsd:string) "phosphorylethanolamine transferase activity"^^xsd:string) AnnotationAssertion( "phosphoethanolamine cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.14"^^xsd:string) "ethanolamine phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.14"^^xsd:string) "Catalysis of the reaction: CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.1"^^xsd:string) "phosphorylethanolamine-glyceride transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.1"^^xsd:string) "EPT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.1"^^xsd:string) "Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.1"^^xsd:string) "CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.1"^^xsd:string) "CDPethanolamine diglyceride phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.1"^^xsd:string) "diacylglycerol ethanolaminephosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ethanolaminephosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.18"^^xsd:string) "neuraminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.18"^^xsd:string) "sialidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.18"^^xsd:string) "alpha-neuraminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.18"^^xsd:string) "N-acylneuraminate glycohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.18"^^xsd:string) "acetylneuraminyl hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.18"^^xsd:string) "acetylneuraminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.18"^^xsd:string) "Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates."^^xsd:string) AnnotationAssertion(rdfs:label "exo-alpha-sialidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.11"^^xsd:string) "acid phosphoanhydride phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.11"^^xsd:string) "metaphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.11"^^xsd:string) "Gra-Pase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.11"^^xsd:string) "polyphosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.11"^^xsd:string) "exopolypase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.11"^^xsd:string) "Catalysis of the reaction: polyphosphate(n) + H2O = polyphosphate(n-1) + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "exopolyphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.21"^^xsd:string) "presqualene-diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.21"^^xsd:string) "presqualene synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "farnesyl-diphosphate farnesyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.21"^^xsd:string) "Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.21"^^xsd:string) "farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.29"^^xsd:string) "trans,trans-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.29"^^xsd:string) "geranylgeranyl pyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.29"^^xsd:string) Annotation( "RHEA:17656"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "farnesyltranstransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.29"^^xsd:string) "farnesyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.29"^^xsd:string) "geranylgeranyl-diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.29"^^xsd:string) "geranylgeranyl-PP synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.29"^^xsd:string) "geranylgeranyl pyrophosphate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "fatty-acid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.85"^^xsd:string) "acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.85"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+."^^xsd:string) AnnotationAssertion(rdfs:label "fatty acid synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "[acyl-carrier protein] S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.38"^^xsd:string) "ACP acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.38"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + [acyl-carrier protein] = CoA + acetyl-[acyl-carrier protein]."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.38"^^xsd:string) "acetyl-CoA:acyl-carrier-protein S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.38"^^xsd:string) "acetyl coenzyme A-acyl-carrier-protein transacylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[acyl-carrier-protein] S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.38"^^xsd:string) "acyl-carrier-protein acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.38"^^xsd:string) "ACAT activity"^^xsd:string) AnnotationAssertion( "ACP S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.38"^^xsd:string) "acyl-carrier-protein S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.38"^^xsd:string) "ACPacetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.38"^^xsd:string) "acyl-carrier-proteinacetyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.39"^^xsd:string) "malonyl-CoA:ACP transacylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[acyl-carrier-protein] S-malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.39"^^xsd:string) "FabD"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.39"^^xsd:string) "malonyl-CoA:acyl carrier protein transacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.39"^^xsd:string) "acyl carrier proteinmalonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.39"^^xsd:string) "MCAT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.39"^^xsd:string) "acyl-carrier-protein S-malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.39"^^xsd:string) "malonyl-CoA:acyl-carrier-protein S-malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.39"^^xsd:string) "malonyl transacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.39"^^xsd:string) "malonyl coenzyme A-acyl carrier protein transacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.39"^^xsd:string) "Catalysis of the reaction: malonyl-CoA + [acyl-carrier protein] = CoA + malonyl-[acyl-carrier protein]."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.39"^^xsd:string) "malonyl-CoA-acyl carrier protein transacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.39"^^xsd:string) "acyl carrier protein malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.39"^^xsd:string) "malonyl transferase activity"^^xsd:string) AnnotationAssertion( "ACP S-malonyltransferase activity"^^xsd:string) AnnotationAssertion( "[acyl-carrier protein] S-malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.39"^^xsd:string) "malonyl-CoA:AcpM transacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.39"^^xsd:string) "MAT"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "beta-ketoacyl-acyl carrier protein synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-oxoacyl-[acyl-carrier-protein] synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "beta-ketoacyl-acyl-carrier-protein synthase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "beta-ketoacyl-[acyl carrier protein] synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "beta-ketoacyl-ACP synthetase activity"^^xsd:string) AnnotationAssertion( "3-oxoacyl-ACP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "beta-ketoacyl-acyl carrier protein synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "condensing enzyme activity"^^xsd:string) AnnotationAssertion( "3-oxoacyl-[acyl-carrier protein] synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "KAS I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "acyl-acyl-carrier-protein:malonyl-acyl-carrier-protein C-acyltransferase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "beta-ketoacylsynthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "3-oxoacyl-acyl-carrier-protein synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "acyl-malonyl acyl carrier protein-condensing enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "3-oxoacyl:ACP synthase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "beta-ketoacyl synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "acyl-malonyl(acyl-carrier-protein)-condensing enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "FabF1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "FabB"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "KASI"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "fatty acid condensing enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "3-ketoacyl-acyl carrier protein synthase activity"^^xsd:string) AnnotationAssertion( "ketoacyl-ACP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "beta-ketoacyl acyl carrier protein synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.41"^^xsd:string) "beta-ketoacyl-ACP synthase I activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.100"^^xsd:string) "beta-ketoacyl reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.100"^^xsd:string) "Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.100"^^xsd:string) "3-ketoacyl acyl carrier protein reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.100"^^xsd:string) "beta-ketoacyl-ACP reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.100"^^xsd:string) "beta-ketoacyl-acyl-carrier protein(ACP) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.100"^^xsd:string) "3-oxoacyl-ACPreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.100"^^xsd:string) "beta-ketoacyl-acyl carrier protein reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.100"^^xsd:string) "3-oxoacyl-acyl-carrier-protein reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.100"^^xsd:string) "NADPH-specific 3-oxoacyl-acylcarrier proteinreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.100"^^xsd:string) "(3R)-3-hydroxyacyl-acyl-carrier-protein:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.100"^^xsd:string) "beta-ketoacyl acyl carrier protein (ACP) reductase activity"^^xsd:string) AnnotationAssertion( "3-oxoacyl-ACP reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.100"^^xsd:string) "beta-ketoacyl thioester reductase activity"^^xsd:string) AnnotationAssertion( "3-oxoacyl-[acyl-carrier protein] reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.61"^^xsd:string) "(3R)-3-hydroxypalmitoyl-acyl-carrier-protein hydro-lyase (hexadec-2-enoyl-acyl-carrier protein-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.61"^^xsd:string) "D-3-hydroxypalmitoyl-acyl-carrier-protein dehydratase activity"^^xsd:string) AnnotationAssertion( "3-hydroxypalmitoyl-[acyl-carrier protein] dehydratase activity"^^xsd:string) AnnotationAssertion( "3-hydroxypalmitoyl-ACP dehydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.61"^^xsd:string) "D-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.61"^^xsd:string) "3-hydroxypalmitoyl-acyl-carrier-protein dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.61"^^xsd:string) "beta-hydroxypalmityl-ACP dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.61"^^xsd:string) "(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.61"^^xsd:string) "Catalysis of the reaction: (3R)-3-hydroxypalmitoyl-[acyl-carrier protein] = 2-hexadecenoyl-[acyl-carrier protein] + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.61"^^xsd:string) "beta-hydroxypalmitoyl thioester dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.61"^^xsd:string) "(3R)-3-hydroxypalmitoyl-acyl-carrier-protein hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.61"^^xsd:string) "beta-hydroxypalmitoyl-acyl carrier protein dehydrase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.9"^^xsd:string) "Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.9"^^xsd:string) "enoyl-[acyl-carrier protein] reductase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.9"^^xsd:string) "NADH-specific enoyl-ACP reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.9"^^xsd:string) "acyl-acyl-carrier-protein:NAD+ oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.9"^^xsd:string) "enoyl-acyl-carrier-protein reductase (NADH)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.9"^^xsd:string) "NADH-enoyl acyl carrier protein reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "enoyl-[acyl-carrier-protein] reductase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.9"^^xsd:string) "enoyl-ACP reductase (NADH) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.10"^^xsd:string) "enoyl-acyl-carrier-protein reductase (NADPH, B-specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.10"^^xsd:string) "acyl-acyl-carrier-protein:NADP+ oxidoreductase (B-specific)"^^xsd:string) AnnotationAssertion(rdfs:label "enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity"^^xsd:string) AnnotationAssertion( "enoyl-[acyl-carrier protein] reductase (NADPH, B-specific) activity"^^xsd:string) AnnotationAssertion( "enoyl-ACP reductase (NADPH, B-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.10"^^xsd:string) "enoyl-acyl-carrier-protein reductase (NADPH2, B-specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.10"^^xsd:string) "NADPH 2-enoyl Co A reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.10"^^xsd:string) "Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.10"^^xsd:string) "reductase, enoyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide phosphate)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.10"^^xsd:string) "enoyl acyl-carrier-protein reductase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "oleoyl-[acyl-carrier protein] hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.14"^^xsd:string) "Catalysis of the reaction: oleoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + oleate."^^xsd:string) AnnotationAssertion( "oleoyl-ACP hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.14"^^xsd:string) "oleoyl-acyl-carrier-protein hydrolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.14"^^xsd:string) "oleoyl-ACP thioesterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oleoyl-[acyl-carrier-protein] hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.14"^^xsd:string) "oleoyl-acyl carrier protein thioesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.86"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADH + 2n NADPH + 4n H+ = a long-chain acyl-CoA + n CoA + n CO2 + 2n NAD+ + 2n NADP+."^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "fatty acyl CoA synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.86"^^xsd:string) "yeast fatty acid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.86"^^xsd:string) "acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl- reducing)"^^xsd:string) AnnotationAssertion(rdfs:label "fatty-acyl-CoA synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.16.3.1"^^xsd:string) "ferroxidase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.3.1"^^xsd:string) "ceruloplasmin activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.3.1"^^xsd:string) "Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O."^^xsd:string) AnnotationAssertion( "multicopper ferroxidase iron transport mediator activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.3.1"^^xsd:string) "iron(II): oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.3.1"^^xsd:string) "ferro:O2 oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ferroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.3.1"^^xsd:string) "ferroxidase, iron II:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.3.1"^^xsd:string) "caeruloplasmin"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.3.1"^^xsd:string) "Fe(II):oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.18.1.2"^^xsd:string) "NADPH:ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.2"^^xsd:string) "ferredoxin-TPN reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.2"^^xsd:string) "ferredoxin:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.2"^^xsd:string) "ferredoxin-nicotinamide adenine dinucleotide phosphate reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ferredoxin-NADP+ reductase activity"^^xsd:string) AnnotationAssertion( "ferredoxin-NADP reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.2"^^xsd:string) Annotation( "GOC:kd"^^xsd:string) "Catalysis of the reaction: reduced ferredoxin + NADP+ = oxidized ferredoxin + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.2"^^xsd:string) "NADP:ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.2"^^xsd:string) "TPNH-ferredoxin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.2"^^xsd:string) "ferredoxin-nicotinamide-adenine dinucleotide phosphate (oxidized) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.2"^^xsd:string) "ferredoxin-NADP oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.2"^^xsd:string) "ferredoxin-NADP-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.2"^^xsd:string) "reduced nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.99.1.1"^^xsd:string) "protoheme ferrolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.1"^^xsd:string) "heme synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ferrochelatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.1"^^xsd:string) "iron chelatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.1"^^xsd:string) "ferro-protoporphyrin chelatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.1"^^xsd:string) "protoheme ferro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.1"^^xsd:string) "heme synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.1"^^xsd:string) "protoheme ferro-lyase (protoporphyrin-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.1"^^xsd:string) Annotation( "RHEA:22587"^^xsd:string) "Catalysis of the reaction: protoheme = Fe(2+) + protoporphyrin IX."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.17"^^xsd:string) "N(10)-formyltetrahydropteroyldiglutamate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.17"^^xsd:string) "folylpoly-gamma-glutamate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.17"^^xsd:string) "folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase activity"^^xsd:string) AnnotationAssertion( "folylpolyglutamate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.17"^^xsd:string) "N10-formyltetrahydropteroyldiglutamate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.17"^^xsd:string) "Catalysis of the reaction: ATP + tetrahydrofolyl-(Glu)(n) + L-glutamate = ADP + phosphate + tetrahydrofolyl-(Glu)(n+1)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.17"^^xsd:string) "folylpolyglutamyl synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tetrahydrofolylpolyglutamate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.17"^^xsd:string) "tetrahydrofolyl-[gamma-Glu]n:L-glutamate gamma-ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.17"^^xsd:string) "tetrahydropteroyl-[gamma-polyglutamate]:L-glutamate gamma-ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.17"^^xsd:string) "folylpolyglutamate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.17"^^xsd:string) "tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.17"^^xsd:string) "folate polyglutamate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.17"^^xsd:string) "FPGS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.17"^^xsd:string) "formyltetrahydropteroyldiglutamate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.17"^^xsd:string) "tetrahydrofolate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.17"^^xsd:string) "folylpoly(gamma-glutamate) synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.49"^^xsd:string) Annotation( "RHEA:21951"^^xsd:string) "Catalysis of the reaction: formamide + H(2)O = formate + NH(4)(+)."^^xsd:string) AnnotationAssertion( "formamide hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "formamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.49"^^xsd:string) "formamide amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) "10-formyl-THF synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.3"^^xsd:string) "formate:tetrahydrofolate ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.3"^^xsd:string) "tetrahydrofolic formylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.3"^^xsd:string) "formyltetrahydrofolate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.3"^^xsd:string) "tetrahydrofolate formylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.3"^^xsd:string) "10-formyltetrahydrofolate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.3"^^xsd:string) "Catalysis of the reaction: ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate."^^xsd:string) AnnotationAssertion(rdfs:label "formate-tetrahydrofolate ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.46"^^xsd:string) "beta-D-fructose-2,6-bisphosphate 2-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "fructose-2,6-bisphosphate 2-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.46"^^xsd:string) "D-fructose-2,6-bisphosphate 2-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.46"^^xsd:string) "Catalysis of the reaction: D-fructose 2,6-bisphosphate + H2O = D-fructose-6-phosphate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.46"^^xsd:string) "fructose-2,6-bisphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.13"^^xsd:string) "fructose 1,6-diphosphate aldolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "fructose-bisphosphate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.13"^^xsd:string) "fructose diphosphate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.13"^^xsd:string) "fructose 1-phosphate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.13"^^xsd:string) "aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.13"^^xsd:string) "diphosphofructose aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.13"^^xsd:string) "1,6-diphosphofructose aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.13"^^xsd:string) "zymohexase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.13"^^xsd:string) "fructoaldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.13"^^xsd:string) "Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde-3-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.13"^^xsd:string) "D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.13"^^xsd:string) "SMALDO"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.13"^^xsd:string) "ketose 1-phosphate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.13"^^xsd:string) "D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.13"^^xsd:string) "phosphofructoaldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.13"^^xsd:string) "fructose-1,6-bisphosphate triosephosphate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.13"^^xsd:string) "fructose 1-monophosphate aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.2"^^xsd:string) "fumarase activity"^^xsd:string) AnnotationAssertion(rdfs:label "fumarate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.2"^^xsd:string) "(S)-malate hydro-lyase (fumarate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.2"^^xsd:string) "L-malate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.2"^^xsd:string) "(S)-malate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.2"^^xsd:string) Annotation( "RHEA:12463"^^xsd:string) "Catalysis of the reaction: (S)-malate = fumarate + H(2)O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.7.1.2"^^xsd:string) "beta-diketonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.2"^^xsd:string) "4-fumarylacetoacetate fumarylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.2"^^xsd:string) "fumarylacetoacetate hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "fumarylacetoacetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.2"^^xsd:string) Annotation( "RHEA:10247"^^xsd:string) "Catalysis of the reaction: 4-fumarylacetoacetate + H(2)O = acetoacetate + fumarate + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.6"^^xsd:string) "galactokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.6"^^xsd:string) Annotation( "RHEA:13556"^^xsd:string) "Catalysis of the reaction: D-galactose + ATP = alpha-D-galactose 1-phosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.6"^^xsd:string) "ATP:D-galactose 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.6"^^xsd:string) "ATP:D-galactose-1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactokinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.46"^^xsd:string) "Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine."^^xsd:string) AnnotationAssertion(rdfs:label "galactosylceramidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.46"^^xsd:string) "ceramide galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.46"^^xsd:string) "galactocerebroside-beta-D-galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.46"^^xsd:string) "galcerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.46"^^xsd:string) "D-galactosyl-N-acylsphingosine galactohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.46"^^xsd:string) "galactocerebroside beta-galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.46"^^xsd:string) "galactosylcerebrosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.46"^^xsd:string) "cerebroside beta-galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.46"^^xsd:string) "beta-galactocerebrosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.46"^^xsd:string) "beta-galactosylceramidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.46"^^xsd:string) "galactocerebroside galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.46"^^xsd:string) "lactosylceramidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.46"^^xsd:string) "lactosylceramidase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.46"^^xsd:string) "galactocerebrosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.46"^^xsd:string) "galactosylceramidase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.46"^^xsd:string) "galactosylceramide beta-galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.46"^^xsd:string) "cerebroside galactosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "farnesyl-diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.10"^^xsd:string) "geranyl transferase I"^^xsd:string) AnnotationAssertion(rdfs:label "geranyltranstransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.10"^^xsd:string) "FPP synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.10"^^xsd:string) "geranyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.10"^^xsd:string) Annotation( "RHEA:19364"^^xsd:string) "Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.10"^^xsd:string) "farnesylpyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion( "farnesyl pyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.10"^^xsd:string) "geranyl-diphosphate:isopentenyl-diphosphate geranyltranstransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.10"^^xsd:string) "farnesyl diphosphate synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.58"^^xsd:string) "exo-1,3-beta-D-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.58"^^xsd:string) "exo (1->3)-beta-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.58"^^xsd:string) "exo-beta-(1->3)-D-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.58"^^xsd:string) "Catalysis of the successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.58"^^xsd:string) "exo-beta-1,3-D-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.58"^^xsd:string) "1,3-beta-glucan glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.58"^^xsd:string) "beta-1,3-glucan exo-hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "glucan 1,3-beta-glucosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucan exo-1,3-beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.58"^^xsd:string) "exo-1,3-beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.58"^^xsd:string) "exo-beta-1,3-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.58"^^xsd:string) "exo-1,3-beta-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.58"^^xsd:string) "exo-beta-(1->3)-glucanohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.3"^^xsd:string) "glucose amylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.3"^^xsd:string) "gamma-1,4-glucan glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.3"^^xsd:string) "gamma-amylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.3"^^xsd:string) "1,4-alpha-D-glucan glucohydrolase activity"^^xsd:string) AnnotationAssertion( "glucoamylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.3"^^xsd:string) "Catalysis of the hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.3"^^xsd:string) "exo-1,4-alpha-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.3"^^xsd:string) "amyloglucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.3"^^xsd:string) "lysosomal alpha-glucosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucan 1,4-alpha-glucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.2"^^xsd:string) "Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose-6-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.2"^^xsd:string) "ATP:D-glucose 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.2"^^xsd:string) "glucose kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.2"^^xsd:string) "glucokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "glucokinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.17"^^xsd:string) "gulonolactonase activity"^^xsd:string) AnnotationAssertion(rdfs:label "gluconolactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.17"^^xsd:string) "aldonolactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.17"^^xsd:string) "D-glucono-1,5-lactone lactonohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.17"^^xsd:string) "Catalysis of the reaction: D-glucono-1,5-lactone + H2O = D-gluconate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.17"^^xsd:string) "lactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.17"^^xsd:string) "glucono-delta-lactonase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.99.6"^^xsd:string) Annotation( "RHEA:12175"^^xsd:string) "Catalysis of the reaction: D-glucosamine 6-phosphate + H(2)O = beta-D-fructose 6-phosphate + NH(4)(+)."^^xsd:string) AnnotationAssertion(rdfs:label "glucosamine-6-phosphate deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.6"^^xsd:string) "phosphoglucosaminisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.6"^^xsd:string) "glucosamine-6-phosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.6"^^xsd:string) "glucosaminephosphate isomerase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.6"^^xsd:string) "glucosamine phosphate deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.6"^^xsd:string) "GlcN6P deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.6"^^xsd:string) "2-amino-2-deoxy-D-glucose-6-phosphate aminohydrolase (ketol isomerizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.6"^^xsd:string) "aminodeoxyglucosephosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.6"^^xsd:string) "phosphoglucosamine isomerase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.4"^^xsd:string) "glucosamine 6-phosphate acetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.4"^^xsd:string) "glucosamine-6-phosphate acetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.4"^^xsd:string) "phosphoglucosamine acetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.4"^^xsd:string) "aminodeoxyglucosephosphate acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.4"^^xsd:string) "acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.4"^^xsd:string) "D-glucosamine-6-P N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.4"^^xsd:string) "phosphoglucosamine transacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.4"^^xsd:string) "phosphoglucosamine N-acetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.4"^^xsd:string) "N-acetylglucosamine-6-phosphate synthase activity"^^xsd:string) AnnotationAssertion( "glucosamine-phosphate N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.4"^^xsd:string) Annotation( "RHEA:10295"^^xsd:string) "Catalysis of the reaction: D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "glucosamine 6-phosphate N-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.2"^^xsd:string) "D-glucose:acceptor 1-oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.10"^^xsd:string) "D-glucose:(acceptor) 1-oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.10"^^xsd:string) "Catalysis of the reaction: D-glucose + acceptor = D-glucono-1,5-lactone + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.10"^^xsd:string) "glucose dehydrogenase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.10"^^xsd:string) "glucose dehydrogenase (Aspergillus) activity"^^xsd:string) AnnotationAssertion( "glucose dehydrogenase (acceptor) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "G6PDH"^^xsd:string) AnnotationAssertion( "glucose-6-phosphate 1-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.49"^^xsd:string) "Entner-doudoroff enzyme"^^xsd:string) AnnotationAssertion( "glucose 6-phosphate dehydrogenase (NADP) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.49"^^xsd:string) "zwischenferment"^^xsd:string) AnnotationAssertion( "D-glucose 6-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion( "NADP-glucose-6-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion( "NADP-dependent glucose 6-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.49"^^xsd:string) "G6PD activity"^^xsd:string) AnnotationAssertion( "6-phosphoglucose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.49"^^xsd:string) "Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.49"^^xsd:string) "D-glucose-6-phosphate:NADP+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion( "GDH"^^xsd:string) AnnotationAssertion( "Zwischenferment"^^xsd:string) AnnotationAssertion( "6-phosphoglucose dehydrogenas"^^xsd:string) AnnotationAssertion(rdfs:label "glucose-6-phosphate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.9"^^xsd:string) Annotation( "RHEA:16692"^^xsd:string) "Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.9"^^xsd:string) "glucose 6-phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.9"^^xsd:string) "D-glucose-6-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucose-6-phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.1.9"^^xsd:string) "Catalysis of the reaction: D-glucose 6-phosphate = D-fructose 6-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "glucose-6-phosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.9"^^xsd:string) "D-glucose-6-phosphate aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.9"^^xsd:string) "hexose phosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.9"^^xsd:string) "hexose monophosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.9"^^xsd:string) "phosphohexomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.9"^^xsd:string) "glucose phosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.9"^^xsd:string) "phosphoglucoisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.9"^^xsd:string) "hexosephosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.9"^^xsd:string) "D-glucose-6-phosphate ketol-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.9"^^xsd:string) "phosphohexose isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.9"^^xsd:string) "phosphohexoisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.9"^^xsd:string) "oxoisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.9"^^xsd:string) "phosphosaccharomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.9"^^xsd:string) "phosphoglucose isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.45"^^xsd:string) "ceramide glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.45"^^xsd:string) "Catalysis of the reaction: D-glucosyl-N-acylsphingosine + H2O = D-glucose + N-acylsphingosine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.45"^^xsd:string) "GlcCer-beta-glucosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucosylceramidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.45"^^xsd:string) "glucosylsphingosine beta-D-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.45"^^xsd:string) "beta-glucosylceramidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.45"^^xsd:string) "glucosylsphingosine beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.45"^^xsd:string) "D-glucosyl-N-acylsphingosine glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.45"^^xsd:string) "beta-glucocerebrosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.45"^^xsd:string) "acid beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.45"^^xsd:string) "psychosine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.45"^^xsd:string) "beta-D-glucocerebrosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.45"^^xsd:string) "glucosylcerebrosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.45"^^xsd:string) "glucocerebrosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.45"^^xsd:string) "glucosphingosine glucosylhydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.2.11"^^xsd:string) "ATP-L-glutamate 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.11"^^xsd:string) "gamma-glutamyl kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.11"^^xsd:string) "ATP:gamma-L-glutamate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.11"^^xsd:string) "gamma-glutamate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.11"^^xsd:string) "ATP:L-glutamate 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamate 5-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.11"^^xsd:string) Annotation( "RHEA:14880"^^xsd:string) "Catalysis of the reaction: L-glutamate + ATP = L-glutamyl 5-phosphate + ADP + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.11"^^xsd:string) "glutamate kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.41"^^xsd:string) "gamma-glutamylphosphate reductase activity"^^xsd:string) AnnotationAssertion( "glutamate-phosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.41"^^xsd:string) "gamma-glutamyl phosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.41"^^xsd:string) "glutamyl-gamma-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.41"^^xsd:string) "beta-glutamylphosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.41"^^xsd:string) "L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.41"^^xsd:string) Annotation( "RHEA:19544"^^xsd:string) "Catalysis of the reaction: L-glutamate 5-semialdehyde + NADP(+) + phosphate = L-glutamyl 5-phosphate + H(+) + NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "glutamate-5-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.41"^^xsd:string) "glutamate semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion( "glutamylphosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.41"^^xsd:string) "glutamate-gamma-semialdehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.15"^^xsd:string) "aspartic alpha-decarboxylase"^^xsd:string) AnnotationAssertion(rdfs:label "glutamate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.15"^^xsd:string) "cysteic acid decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.15"^^xsd:string) "gamma-glutamate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.15"^^xsd:string) "L-glutamic decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.15"^^xsd:string) "L-glutamate alpha-decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.15"^^xsd:string) "L-aspartate-alpha-decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.15"^^xsd:string) "Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.15"^^xsd:string) "L-glutamic acid decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.15"^^xsd:string) "L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.15"^^xsd:string) "L-glutamate 1-carboxy-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.1.2"^^xsd:string) "NAD:glutamate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.2"^^xsd:string) "L-glutamate:NAD+ oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.2"^^xsd:string) "NAD-linked glutamic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.2"^^xsd:string) "glutamate dehydrogenase (NAD)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.2"^^xsd:string) "glutamic acid dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.2"^^xsd:string) "NAD-dependent glutamic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.2"^^xsd:string) "glutamic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.2"^^xsd:string) "NADH-linked glutamate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.2"^^xsd:string) "NAD-specific glutamic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.2"^^xsd:string) "glutamate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.2"^^xsd:string) "NAD-linked glutamate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.2"^^xsd:string) "NAD-specific glutamate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamate dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.2"^^xsd:string) "NAD-dependent glutamate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.2"^^xsd:string) "L-glutamate dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.2"^^xsd:string) "Catalysis of the reaction: L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.2"^^xsd:string) "NAD-glutamate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutamate dehydrogenase [NAD(P)+] activity"^^xsd:string) AnnotationAssertion( "glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)"^^xsd:string) AnnotationAssertion( "glutamate biosynthesis, using glutamate dehydrogenase (NAD(P)+)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.3"^^xsd:string) "Catalysis of the reaction: L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.3"^^xsd:string) "L-glutamate:NAD(P)+ oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.3"^^xsd:string) "glutamic dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.1.4"^^xsd:string) "L-glutamate:NADP+ oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.4"^^xsd:string) "NAD(P)H-dependent glutamate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.4"^^xsd:string) "L-glutamate dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.4"^^xsd:string) "L-glutamic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.4"^^xsd:string) "NAD(P)-glutamate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.4"^^xsd:string) "Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.4"^^xsd:string) "glutamic acid dehydrogenase"^^xsd:string) AnnotationAssertion(rdfs:label "glutamate dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.4"^^xsd:string) "dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate))"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.4"^^xsd:string) "glutamic dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.1.13"^^xsd:string) "L-glutamate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.13"^^xsd:string) "glutamine-ketoglutaric aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.13"^^xsd:string) "NADPH-glutamate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.13"^^xsd:string) "L-glutamine:2-oxoglutarate aminotransferase, NADPH oxidizing activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.13"^^xsd:string) "glutamate synthetase (NADP) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.13"^^xsd:string) Annotation( "RHEA:15504"^^xsd:string) "Catalysis of the reaction: 2 L-glutamate + NADP(+) = 2-oxoglutarate + L-glutamine + H(+) + NADPH. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + NADP+ + H2O = NH3 + 2-oxoglutarate + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.13"^^xsd:string) "L-glutamate:NADP+ oxidoreductase (transaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.13"^^xsd:string) "NADPH-dependent glutamate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.13"^^xsd:string) "GOGAT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.13"^^xsd:string) "glutamate (reduced nicotinamide adenine dinucleotide phosphate) synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.13"^^xsd:string) "L-glutamate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.13"^^xsd:string) "NADPH-linked glutamate synthase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.13"^^xsd:string) "glutamine amide-2-oxoglutarate aminotransferase (oxidoreductase, NADP) activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamate synthase (NADPH) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.1.2"^^xsd:string) "L-glutamine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.2"^^xsd:string) "L-glutamate:ammonia ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.2"^^xsd:string) "glutamylhydroxamic synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.2"^^xsd:string) Annotation( "RHEA:16172"^^xsd:string) "Catalysis of the reaction: L-glutamate + ATP + NH(4)(+) = L-glutamine + ADP + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "glutamate-ammonia ligase activity"^^xsd:string) AnnotationAssertion( "glutamine synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.2"^^xsd:string) "gamma-glutamylcysteine synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamate-cysteine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.2"^^xsd:string) Annotation( "RHEA:13288"^^xsd:string) "Catalysis of the reaction: L-cysteine + L-glutamate + ATP = L-gamma-glutamyl-L-cysteine + ADP + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.2"^^xsd:string) "gamma-glutamyl-L-cysteine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.2"^^xsd:string) "gamma-glutamylcysteinyl synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.2"^^xsd:string) "L-glutamate:L-cysteine gamma-ligase (ADP-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.35"^^xsd:string) "acetylglutamate-acetylornithine transacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.35"^^xsd:string) "acetylornithine glutamate acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.35"^^xsd:string) "2-N-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.35"^^xsd:string) "N-acetylglutamate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.35"^^xsd:string) "acetylornithinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.35"^^xsd:string) "ornithine acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.35"^^xsd:string) "acetylglutamate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.35"^^xsd:string) "acetylglutamic synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.35"^^xsd:string) "N-acetyl-L-glutamate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.35"^^xsd:string) "N-acetylglutamate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.35"^^xsd:string) "acetylglutamic-acetylornithine transacetylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamate N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.35"^^xsd:string) "ornithine transacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.35"^^xsd:string) "glutamate acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.35"^^xsd:string) "alpha-N-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.35"^^xsd:string) Annotation( "RHEA:15352"^^xsd:string) "Catalysis of the reaction: N(2)-acetyl-L-ornithine + L-glutamate = N-acetyl-L-glutamate + L-ornithine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.35"^^xsd:string) "N2-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.2"^^xsd:string) "Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.2"^^xsd:string) "glutaminase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.2"^^xsd:string) "L-glutaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.2"^^xsd:string) "glutamine aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.2"^^xsd:string) "L-glutamine amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.16"^^xsd:string) "glucosamine 6-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.16"^^xsd:string) "D-fructose-6-phosphate amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.16"^^xsd:string) "glucosaminephosphate isomerase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.16"^^xsd:string) "glucosamine-6-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.16"^^xsd:string) "L-glutamine-D-fructose-6-phosphate amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.16"^^xsd:string) "L-glutamine:D-fructose-6-phosphate isomerase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.16"^^xsd:string) "glucosamine--fructose-6-phosphate aminotransferase (isomerizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.16"^^xsd:string) Annotation( "RHEA:13240"^^xsd:string) "Catalysis of the reaction: beta-D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.16"^^xsd:string) "GlcN6P synthase activity"^^xsd:string) AnnotationAssertion( "glucosamine-6-phosphate isomerase (glutamine-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamine-fructose-6-phosphate transaminase (isomerizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.16"^^xsd:string) "hexosephosphate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.99.7"^^xsd:string) "glutaryl-CoA:(acceptor) 2,3-oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "glutaryl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.7"^^xsd:string) "Catalysis of the reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.7"^^xsd:string) "glutaryl coenzyme A dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.7"^^xsd:string) "glutaryl-CoA:acceptor 2,3-oxidoreductase (decarboxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glutathione reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.7"^^xsd:string) "glutathione S-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.7"^^xsd:string) "NADPH-glutathione reductase activity"^^xsd:string) AnnotationAssertion( "glutathione-disulphide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.7"^^xsd:string) "GSSG reductase activity"^^xsd:string) AnnotationAssertion( "oxidized glutathione reduction"^^xsd:string) AnnotationAssertion(rdfs:label "glutathione-disulfide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.7"^^xsd:string) "NADPH:oxidized-glutathione oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.7"^^xsd:string) "GSH reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.7"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.7"^^xsd:string) "NADPH-GSSG reductase activity"^^xsd:string) AnnotationAssertion( "glutathione reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.7"^^xsd:string) "glutathione:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.3"^^xsd:string) "GSH synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.3"^^xsd:string) Annotation( "RHEA:13560"^^xsd:string) "Catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.3"^^xsd:string) "glutathione synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutathione synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.3"^^xsd:string) "gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.18"^^xsd:string) "glutathione S-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.18"^^xsd:string) "S-(hydroxyalkyl)glutathione lyase activity"^^xsd:string) AnnotationAssertion( "glutathione conjugation reaction"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.18"^^xsd:string) "glutathione S-alkyl transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutathione transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.18"^^xsd:string) "Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.18"^^xsd:string) "glutathione S-aryltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.18"^^xsd:string) "glutathione S-aralkyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.18"^^xsd:string) "glutathione S-alkyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.18"^^xsd:string) "RX:glutathione R-transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.12"^^xsd:string) "triosephosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.12"^^xsd:string) "NADH-glyceraldehyde phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.12"^^xsd:string) "NAD-dependent glyceraldehyde phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.12"^^xsd:string) "glyceraldehyde-3-P-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.12"^^xsd:string) "phosphoglyceraldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.12"^^xsd:string) "3-phosphoglyceraldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.12"^^xsd:string) "dehydrogenase, glyceraldehyde phosphate"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.12"^^xsd:string) "GAPDH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.12"^^xsd:string) "NAD-dependent glyceraldehyde-3-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.12"^^xsd:string) "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.12"^^xsd:string) "D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.12"^^xsd:string) "glyceraldehyde phosphate dehydrogenase (NAD)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.15"^^xsd:string) "sn-glycerol 3-phosphate acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.15"^^xsd:string) "alpha-glycerophosphate acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycerol-3-phosphate O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.15"^^xsd:string) "glycerophosphate acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.15"^^xsd:string) "sn-glycerol-3-phosphate acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.15"^^xsd:string) "glycerophosphate transacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.15"^^xsd:string) "Catalysis of the reaction: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.15"^^xsd:string) "glycerol phosphate transacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.15"^^xsd:string) "acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.15"^^xsd:string) "3-glycerophosphate acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.15"^^xsd:string) "glycerol phosphate acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.15"^^xsd:string) "glycerol 3-phosphate acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.15"^^xsd:string) "ACP:sn-glycerol-3-phosphate acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.8"^^xsd:string) "alpha-glycerophosphate dehydrogenase (NAD) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.8"^^xsd:string) "NAD-dependent glycerol phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.8"^^xsd:string) "L-alpha-glycerol phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.8"^^xsd:string) "NAD-linked glycerol 3-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.8"^^xsd:string) "NAD-alpha-glycerophosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.8"^^xsd:string) "alpha-glycerol phosphate dehydrogenase (NAD) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.8"^^xsd:string) "NADH-dihydroxyacetone phosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.8"^^xsd:string) "hydroglycerophosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.8"^^xsd:string) "L-glycerophosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.8"^^xsd:string) "NAD-dependent glycerol-3-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycerol-3-phosphate dehydrogenase [NAD+] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.8"^^xsd:string) Annotation( "EC:1.1.1.94"^^xsd:string) "Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.8"^^xsd:string) "L-glycerol phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.8"^^xsd:string) "glycerophosphate dehydrogenase (NAD) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.8"^^xsd:string) "glycerol phosphate dehydrogenase (NAD) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.8"^^xsd:string) "NAD-L-glycerol-3-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.8"^^xsd:string) "glycerol 1-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.8"^^xsd:string) "L-alpha-glycerophosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.8"^^xsd:string) "glycerol-3-phosphate dehydrogenase (NAD) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.5.3"^^xsd:string) "FAD-dependent glycerol-3-phosphate dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.3"^^xsd:string) "flavin-linked glycerol-3-phosphate dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.3"^^xsd:string) "Catalysis of the reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.3"^^xsd:string) "glycerophosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycerol-3-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.3"^^xsd:string) "glycerol-3-phosphate CoQ reductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.3"^^xsd:string) Annotation( ) "sn-glycerol-3-phosphate:quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.3"^^xsd:string) "L-glycerophosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.3"^^xsd:string) "sn-glycerol-3-phosphate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.21"^^xsd:string) "glycerol-1-phosphate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.21"^^xsd:string) "alpha-glycerophosphate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.21"^^xsd:string) "L-alpha-glycerol-3-phosphate oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycerol-3-phosphate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.21"^^xsd:string) "glycerol phosphate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.21"^^xsd:string) Annotation( "RHEA:18372"^^xsd:string) "Catalysis of the reaction: sn-glycerol 3-phosphate + O(2) = glycerone phosphate + H(2)O(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.21"^^xsd:string) "L-alpha-glycerophosphate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.21"^^xsd:string) "sn-glycerol-3-phosphate:oxygen 2-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.30"^^xsd:string) Annotation( "RHEA:21647"^^xsd:string) "Catalysis of the reaction: ATP + glycerol = sn-glycerol 3-phosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.30"^^xsd:string) "GK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.30"^^xsd:string) "glycerokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.30"^^xsd:string) "ATP:glycerol 3-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.30"^^xsd:string) "glyceric kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.30"^^xsd:string) "glycerol kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.30"^^xsd:string) "ATP:glycerol-3-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycerol kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.29"^^xsd:string) "acetol kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.29"^^xsd:string) "acetol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.29"^^xsd:string) "dihydroxyacetone kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycerone kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.29"^^xsd:string) "ATP:glycerone phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.29"^^xsd:string) Annotation( "RHEA:15776"^^xsd:string) "Catalysis of the reaction: ATP + glycerone = ADP + glycerone phosphate + 2 H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.2.1"^^xsd:string) "5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycine hydroxymethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.1"^^xsd:string) "serine aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.1"^^xsd:string) "serine transhydroxymethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.1"^^xsd:string) "L-serine hydroxymethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.1"^^xsd:string) "allothreonine aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.1"^^xsd:string) "serine hydroxymethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.1"^^xsd:string) "serine hydroxymethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.1"^^xsd:string) "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.11"^^xsd:string) "UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.11"^^xsd:string) "UDP-glucose-glycogen glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.11"^^xsd:string) "UDP-glycogen synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycogen (starch) synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.11"^^xsd:string) "UDPG-glycogen synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.11"^^xsd:string) "glycogen (starch) synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.11"^^xsd:string) "UDPG-glycogen transglucosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.11"^^xsd:string) "uridine diphosphoglucose-glycogen glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.11"^^xsd:string) "UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.11"^^xsd:string) "Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UDP + (1,4)-alpha-D-glucosyl(n+1)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.4.2"^^xsd:string) "protein P1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.4.2"^^xsd:string) "glycine:H-protein-lipoyllysine oxidoreductase (decarboxylating, acceptor-amino-methylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.4.2"^^xsd:string) "Catalysis of the reaction: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.4.2"^^xsd:string) "glycine-cleavage complex"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.4.2"^^xsd:string) "glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.4.2"^^xsd:string) "glycine decarboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycine dehydrogenase (decarboxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.4.2"^^xsd:string) "glycine-cleavage complex P-protein activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.4.2"^^xsd:string) "P-protein"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.4.2"^^xsd:string) "glycine cleavage system P-protein activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage."^^xsd:string) AnnotationAssertion( "glycolipid mannosyl transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycolipid mannosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.131"^^xsd:string) "guanosine diphosphomannose-oligosaccharide-lipid mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.131"^^xsd:string) "oligosaccharide-lipid mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.131"^^xsd:string) "GDP-D-mannose:D-Man-alpha-(1->3)-[D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,2-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.131"^^xsd:string) "Catalysis of the reaction: an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP + 2 H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.131"^^xsd:string) "glycolipid 2-alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.131"^^xsd:string) "GDP-mannose-oligosaccharide-lipid mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.131"^^xsd:string) "GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.132"^^xsd:string) "GDP-mannose-oligosaccharide-lipid mannosyltransferase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.132"^^xsd:string) "Catalysis of the reaction: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP + H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->3)-D-mannosyl-D-mannose linkage."^^xsd:string) AnnotationAssertion(rdfs:label "GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.132"^^xsd:string) "glycolipid 3-alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.132"^^xsd:string) "GDP-mannose:glycolipid 1,3-alpha-D-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.132"^^xsd:string) Annotation( ) "GDP-D-mannose:D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol 3-alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.132"^^xsd:string) "guanosine diphosphomannose-oligosaccharide-lipid II mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.132"^^xsd:string) "mannosyltransferase II activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.97"^^xsd:string) "tetradecanoyl-CoA:glycylpeptide N-tetradecanoyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycylpeptide N-tetradecanoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.97"^^xsd:string) "peptide N-tetradecanoyltransferase activity"^^xsd:string) AnnotationAssertion( "N-myristoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.97"^^xsd:string) "protein N-myristoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.97"^^xsd:string) "Catalysis of the reaction: tetradecanoyl-CoA + glycyl-peptide = CoA + N-tetradecanoylglycyl-peptide."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.97"^^xsd:string) "myristoyl-coenzyme A:protein N-myristoyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.97"^^xsd:string) "myristoyl-CoA-protein N-myristoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.97"^^xsd:string) "peptide N-myristoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.97"^^xsd:string) "myristoylating enzymes"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.40"^^xsd:string) "A-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.40"^^xsd:string) "fucosylgalactose acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.40"^^xsd:string) "blood-group substance A-dependent acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.40"^^xsd:string) "histo-blood group A acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.40"^^xsd:string) "fucosylgalactose alpha-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.40"^^xsd:string) "UDP-GalNAc:Fucalpha1->2Galalpha1->3-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.40"^^xsd:string) "blood-group substance alpha-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.40"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.40"^^xsd:string) "UDP-N-acetyl-D-galactosamine:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose 3-N-acetyl-D-galactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.40"^^xsd:string) "alpha-3-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.40"^^xsd:string) "histo-blood group A transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.40"^^xsd:string) "fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.40"^^xsd:string) "histo-blood group A glycosyltransferase (Fucalpha1->2Galalpha1->3-N-acetylgalactosaminyltransferase)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.40"^^xsd:string) "A transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.40"^^xsd:string) "UDP-N-acetyl-D-galactosamine:alpha-L-fucosyl-1,2-D-galactose 3-N-acetyl-D-galactosaminyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.37"^^xsd:string) "UDP-galactose:alpha-L-fucosyl-(1,2)-D-galactoside 3-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.37"^^xsd:string) "blood-group substance beta-dependent galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.37"^^xsd:string) "histo-blood group B transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.37"^^xsd:string) "blood-group substance B-dependent galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.37"^^xsd:string) "UDPgalactose:alpha-L-fucosyl-(1->2)-D-galactoside 3-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.37"^^xsd:string) "Catalysis of the reaction: UDP-galactose + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-alpha-D-galactosyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.37"^^xsd:string) "UDP-galactose:alpha-L-fucosyl-(1->2)-D-galactoside 3-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.37"^^xsd:string) "B transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.37"^^xsd:string) "[blood group substance] alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.37"^^xsd:string) "histo-blood substance B-dependent galactosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "fucosylgalactoside 3-alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.37"^^xsd:string) "fucosylglycoprotein 3-alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.37"^^xsd:string) "UDPgalactose:alpha-L-fucosyl-(1,2)-D-galactoside 3-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.37"^^xsd:string) "histo-blood substance beta-dependent galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.37"^^xsd:string) "UDPgalactose:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose 3-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "glycoprotein-fucosylgalactoside alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.37"^^xsd:string) "UDPgalactose:O-alpha-L-fucosyl(1,2)D-galactose alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.37"^^xsd:string) "UDPgalactose:O-alpha-L-fucosyl(1->2)D-galactose alpha-D-galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.42"^^xsd:string) "GDPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.42"^^xsd:string) Annotation( "PMID:2989286"^^xsd:string) "Catalysis of the reaction: GDP + H2O = GMP + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "guanosine 5'-diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.42"^^xsd:string) "GDP phosphohydrolase activity"^^xsd:string) AnnotationAssertion( "guanosine diphosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "guanosine-diphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.6.1.2"^^xsd:string) "Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate."^^xsd:string) AnnotationAssertion( "receptor guanylate cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.2"^^xsd:string) "guanyl cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.2"^^xsd:string) "GTP diphosphate-lyase (cyclizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.2"^^xsd:string) "GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "guanylate cyclase activity"^^xsd:string) AnnotationAssertion( "guanylyl cyclase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.4.8"^^xsd:string) "5'-GMP kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "guanylate kinase activity"^^xsd:string) AnnotationAssertion( "membrane-associated guanylate kinase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.8"^^xsd:string) "deoxyguanylate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.8"^^xsd:string) "ATP:(d)GMP phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.8"^^xsd:string) "ATP:GMP phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.8"^^xsd:string) "guanosine monophosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.8"^^xsd:string) "GMP kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.8"^^xsd:string) "Catalysis of the reaction: ATP + GMP = ADP + GDP."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "helicase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA or RNA helix."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.3"^^xsd:string) "ORP33 proteins"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.3"^^xsd:string) "haem oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.3"^^xsd:string) "heme,hydrogen-donor:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)"^^xsd:string) AnnotationAssertion( "haem oxygenase (decyclizing) activity"^^xsd:string) AnnotationAssertion(rdfs:label "heme oxygenase (decyclizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.3"^^xsd:string) "heme oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.3"^^xsd:string) "haem oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.3"^^xsd:string) "Catalysis of the reaction: heme + 3 donor-H2 + 3 O2 = biliverdin + Fe2+ + CO + 3 acceptor + 3 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.3"^^xsd:string) "heme oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "heparan sulfate 2-O-sulfotransferase activity"^^xsd:string) AnnotationAssertion( "heparan-sulfate 2-O-sulphotransferase activity"^^xsd:string) AnnotationAssertion( "heparin 2-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9153262"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 2-O-sulfate; results in 2-O-sulfation of iduronic acid residues in heparan sulfate."^^xsd:string) AnnotationAssertion( "heparin-sulphate 2-sulphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.114"^^xsd:string) "S-adenosyl-L-methionine:3-hexaprenyl-4,5-dihydroxylate O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hexaprenyldihydroxybenzoate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.114"^^xsd:string) "DHHB methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.114"^^xsd:string) "dihydroxyhexaprenylbenzoate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.114"^^xsd:string) "DHHB-Mt activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.114"^^xsd:string) "3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.114"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + 3-hexaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-hexaprenyl-4-hydroxy-5-methoxybenzoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.1"^^xsd:string) "Catalysis of the reaction: ATP + D-hexose = ADP + D-hexose 6-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.1"^^xsd:string) "ATP-dependent hexokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.1"^^xsd:string) "hexokinase D"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.1"^^xsd:string) "hexokinase type I activity"^^xsd:string) AnnotationAssertion(rdfs:label "hexokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.1"^^xsd:string) "hexokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.1"^^xsd:string) "glucose ATP phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.1"^^xsd:string) "hexokinase type IV"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.1"^^xsd:string) "hexokinase type III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.1"^^xsd:string) "hexokinase type IV (glucokinase) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.1"^^xsd:string) "hexokinase type II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.1"^^xsd:string) "ATP:D-hexose 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.1"^^xsd:string) "hexokinase type IV glucokinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histidine ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "histidine alpha-deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "histidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.3"^^xsd:string) "L-histidine ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.3"^^xsd:string) "L-histidine ammonia-lyase (urocanate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.3"^^xsd:string) "Catalysis of the reaction: L-histidine = urocanate + NH3."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "histidinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.22"^^xsd:string) "Catalysis of the reaction: L-histidine = histamine + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.22"^^xsd:string) "L-histidine carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.22"^^xsd:string) "L-histidine carboxy-lyase (histamine-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "histidine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.22"^^xsd:string) "L-histidine decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.23"^^xsd:string) "Catalysis of the reaction: L-histidinol + NAD+ = L-histidine + NADH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "histidinol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.9"^^xsd:string) "L-histidinol phosphate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.9"^^xsd:string) "imidazolylacetolphosphate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.9"^^xsd:string) "L-histidinol-phosphate:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.9"^^xsd:string) "imidazole acetol-phosphate transaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "histidinol-phosphate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.9"^^xsd:string) "histidinol phosphate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.9"^^xsd:string) "IAP transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.9"^^xsd:string) "histidine:imidazoleacetol phosphate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.9"^^xsd:string) "imidazolylacetolphosphate transaminase activity"^^xsd:string) AnnotationAssertion( "histidinol-phosphate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.9"^^xsd:string) "glutamic-imidazoleacetol phosphate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.9"^^xsd:string) "imidazoleacetol phosphate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.9"^^xsd:string) "Catalysis of the reaction: L-histidinol-phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.15"^^xsd:string) "HPpase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.15"^^xsd:string) Annotation( "RHEA:14468"^^xsd:string) "Catalysis of the reaction: L-histidinol phosphate + H(2)O = L-histidinol + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "histidinol-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.15"^^xsd:string) "histidinol phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.15"^^xsd:string) "histidinolphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.15"^^xsd:string) "histidinolphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.15"^^xsd:string) "L-histidinol phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.15"^^xsd:string) "L-histidinol-phosphate phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone."^^xsd:string) AnnotationAssertion( "H2A/H2B histone acetyltransferase activity"^^xsd:string) AnnotationAssertion( "H4/H2A acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "nucleosome-histone acetyltransferase activity"^^xsd:string) AnnotationAssertion( "H3/H4 histone acetyltransferase activity"^^xsd:string) AnnotationAssertion( "histone acetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "acetyl-CoA:histone acetyltransferase activity"^^xsd:string) AnnotationAssertion( "H4/H2 histone acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "histone transacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "histone acetokinase activity"^^xsd:string) AnnotationAssertion( "histone lysine acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "histone acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.-"^^xsd:string) Annotation( "PMID:9893272"^^xsd:string) "Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.17"^^xsd:string) "cytochrome c heme-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.17"^^xsd:string) "cytochrome c synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.17"^^xsd:string) "holocytochrome-c apocytochrome-c-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "holocytochrome-c synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.17"^^xsd:string) "holocytochrome c synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.17"^^xsd:string) "holocytochrome-c apocytochrome-c-lyase (heme-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.17"^^xsd:string) "Catalysis of the reaction: holocytochrome c = apocytochrome c + heme."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.36"^^xsd:string) "2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.36"^^xsd:string) Annotation( "RHEA:15488"^^xsd:string) "Catalysis of the reaction: (-)-homoisocitrate = cis-homoaconitate + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.36"^^xsd:string) "LysF"^^xsd:string) AnnotationAssertion(rdfs:label "homoaconitate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.36"^^xsd:string) "(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate hydro-lyase [(Z)-but-1-ene-1,2,4-tricarboxylate-forming]"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.36"^^xsd:string) "homoaconitase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.36"^^xsd:string) "Lys4"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.36"^^xsd:string) "HACN activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.36"^^xsd:string) "cis-homoaconitase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "homocitrate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.14"^^xsd:string) "acetyl-coenzyme A:2-ketoglutarate C-acetyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.14"^^xsd:string) "acetyl-CoA:2-oxoglutarate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.14"^^xsd:string) "2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA- acetylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.14"^^xsd:string) Annotation( "RHEA:12932"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + acetyl-CoA + H(2)O = CoA + H(+) + homocitrate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.14"^^xsd:string) "2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acetylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.14"^^xsd:string) "homocitrate synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.5"^^xsd:string) "homogentisic acid oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.5"^^xsd:string) "homogentisic acid oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.5"^^xsd:string) "homogentisic oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.5"^^xsd:string) Annotation( "RHEA:15452"^^xsd:string) "Catalysis of the reaction: homogentisate + O(2) = 4-maleylacetoacetate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.5"^^xsd:string) "homogentisate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.5"^^xsd:string) "homogentisicase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.5"^^xsd:string) "homogentisate:oxygen 1,2-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.5"^^xsd:string) "homogentisate dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "homogentisate 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.5"^^xsd:string) "homogentisate oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.3"^^xsd:string) "Catalysis of the reaction: L-homoserine + NADP+ = L-aspartate-4-semialdehyde + NADPH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "homoserine dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.39"^^xsd:string) "homoserine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.39"^^xsd:string) Annotation( "RHEA:13988"^^xsd:string) "Catalysis of the reaction: L-homoserine + ATP = O-phospho-L-homoserine + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.39"^^xsd:string) "ATP:L-homoserine O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.39"^^xsd:string) "HSK"^^xsd:string) AnnotationAssertion(rdfs:label "homoserine kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "homoserine O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.31"^^xsd:string) Annotation( "RHEA:13704"^^xsd:string) "Catalysis of the reaction: L-homoserine + acetyl-CoA = O-acetyl-L-homoserine + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.31"^^xsd:string) "homoserine transacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.31"^^xsd:string) "homoserine O-trans-acetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.31"^^xsd:string) "homoserine acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.31"^^xsd:string) "acetyl-CoA:L-homoserine O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.31"^^xsd:string) "L-homoserine O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.31"^^xsd:string) "homoserine-O-transacetylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.35"^^xsd:string) "hyaluronidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.35"^^xsd:string) "hyaluronate 4-glycanohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hyalurononglucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.35"^^xsd:string) "hyaluronoglucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.35"^^xsd:string) "Catalysis of the random hydrolysis of (1->4) linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.35"^^xsd:string) "chondroitinase I activity"^^xsd:string) AnnotationAssertion( "hyaluronoglucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.35"^^xsd:string) "chondroitinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroxyacylglutathione hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.6"^^xsd:string) "glyoxalase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.6"^^xsd:string) "Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.6"^^xsd:string) "S-2-hydroxylacylglutathione hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.6"^^xsd:string) "S-(2-hydroxyacyl)glutathione hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.6"^^xsd:string) "acetoacetylglutathione hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.50"^^xsd:string) "4-methyl-5-(beta-hydroxyethyl)thiazole kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydroxyethylthiazole kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.50"^^xsd:string) Annotation( "RHEA:24215"^^xsd:string) "Catalysis of the reaction: 5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphoethyl)-thiazole + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.50"^^xsd:string) "hydroxyethylthiazole kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.50"^^xsd:string) "ATP:4-methyl-5-(2-hydroxyethyl)thiazole 2-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.61"^^xsd:string) "porphobilinogen:(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.61"^^xsd:string) "porphobilinogen ammonia-lyase (polymerizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.61"^^xsd:string) "uroporphyrinogen I synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydroxymethylbilane synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.61"^^xsd:string) "uroporphyrinogen synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.61"^^xsd:string) "(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.61"^^xsd:string) "uroporphyrinogen I synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.61"^^xsd:string) "(4-(2-carboxyethyl)-3-(carboxymethyl)pyrrol-2-yl)methyltransferase (hydrolyzing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.61"^^xsd:string) "uroporphyrinogen synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.61"^^xsd:string) Annotation( "RHEA:13188"^^xsd:string) "Catalysis of the reaction: H(2)O + 4 porphobilinogen = hydroxymethylbilane + 4 NH(4)(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.61"^^xsd:string) "pre-uroporphyrinogen synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.61"^^xsd:string) "porphobilinogen deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.61"^^xsd:string) "HMB-synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3.4"^^xsd:string) "HMG-CoA lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.4"^^xsd:string) "3-hydroxy-3-methylglutaryl CoA cleaving enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.4"^^xsd:string) "(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase (acetyl-CoA-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.4"^^xsd:string) "3-hydroxy-3-methylglutaryl coenzyme A lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.4"^^xsd:string) "3-hydroxy-3-methylglutarate-CoA lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.4"^^xsd:string) "hydroxymethylglutaryl coenzyme A lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.4"^^xsd:string) Annotation( "RHEA:24407"^^xsd:string) "Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "hydroxymethylglutaryl-CoA lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.4"^^xsd:string) "(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.4"^^xsd:string) "hydroxymethylglutaryl coenzyme A-cleaving enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.4"^^xsd:string) "3-hydroxy-3-methylglutaryl-CoA lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.34"^^xsd:string) "HMG-CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.34"^^xsd:string) "3-hydroxy-3-methylglutaryl-coenzyme A reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.34"^^xsd:string) Annotation( "RHEA:15992"^^xsd:string) "Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "hydroxymethylglutaryl-CoA reductase (NADPH) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.3.10"^^xsd:string) "3-hydroxy-3-methylglutaryl-coenzyme A synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.10"^^xsd:string) "(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.10"^^xsd:string) "3-hydroxy-3-methylglutaryl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.10"^^xsd:string) "acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.10"^^xsd:string) "(s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.10"^^xsd:string) "3-hydroxy-3-methylglutaryl CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.10"^^xsd:string) "3-hydroxy-3-methylglutaryl-CoA synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydroxymethylglutaryl-CoA synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.10"^^xsd:string) "hydroxymethylglutaryl coenzyme A-condensing enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.10"^^xsd:string) "hydroxymethylglutaryl coenzyme A synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.10"^^xsd:string) Annotation( "RHEA:10191"^^xsd:string) "Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H(2)O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.10"^^xsd:string) "3-hydroxy-3-methylglutaryl coenzyme A synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.10"^^xsd:string) "HMG-CoA synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.10"^^xsd:string) "acetoacetyl coenzyme A transacetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.10"^^xsd:string) "beta-hydroxy-beta-methylglutaryl-CoA synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.10"^^xsd:string) "hydroxymethylglutaryl coenzyme alpha-condensing enzyme activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "guanine-hypoxanthine phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "IMP-GMP pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "inosinic pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "6-mercaptopurine phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "6-hydroxypurine phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "IMP diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "Transphosphoribosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "inosinic acid pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "inosinate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hypoxanthine phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "HGPRTase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "IMP:diphosphate phospho-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "hypoxanthine-guanine phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "inosine 5'-phosphate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "IMP pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "HPRT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "purine-6-thiol phosphoribosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "iduronate-2-sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.13"^^xsd:string) "chondroitinsulfatase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.13"^^xsd:string) "iduronate-2-sulfate sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.13"^^xsd:string) "L-idurono sulfate sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.13"^^xsd:string) "L-iduronate-2-sulfate 2-sulfohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.13"^^xsd:string) "iduronate sulfatase activity"^^xsd:string) AnnotationAssertion( "iduronate-2-sulphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.13"^^xsd:string) "2-sulfo-L-iduronate 2-sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.13"^^xsd:string) "idurono-2-sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.13"^^xsd:string) "sulfoiduronate sulfohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.13"^^xsd:string) "iduronide-2-sulfate sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.13"^^xsd:string) "iduronate sulfate sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.13"^^xsd:string) "Catalysis of the hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.13"^^xsd:string) "L-iduronosulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.13"^^xsd:string) "sulfo-L-iduronate sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.13"^^xsd:string) "L-iduronate 2-sulfate sulfatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "imidazoleglycerol-phosphate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.19"^^xsd:string) Annotation( "RHEA:11043"^^xsd:string) "Catalysis of the reaction: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H(2)O."^^xsd:string) AnnotationAssertion( "imidazoleglycerol phosphate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.19"^^xsd:string) "D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase [3-(imidazol-4-yl)-2-oxopropyl-phosphate-forming]"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.19"^^xsd:string) "D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.19"^^xsd:string) "IGP dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.48"^^xsd:string) "Catalysis of the reaction: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.48"^^xsd:string) "1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.48"^^xsd:string) "indole-3-glycerophosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.48"^^xsd:string) "indoleglycerol phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.48"^^xsd:string) "indoleglycerol phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.48"^^xsd:string) "1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase [cyclizing; 1-C-(3-indolyl)-glycerol-3-phosphate-forming]"^^xsd:string) AnnotationAssertion(rdfs:label "indole-3-glycerol-phosphate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inorganic diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.1"^^xsd:string) "pyrophosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.1"^^xsd:string) "inorganic pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.1"^^xsd:string) Annotation( "RHEA:24579"^^xsd:string) "Catalysis of the reaction: diphosphate + H(2)O = H(+) + 2 phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.1"^^xsd:string) "diphosphate phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.67"^^xsd:string) "phosphatidylinositol kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-phosphatidylinositol 4-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.67"^^xsd:string) "PI kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.67"^^xsd:string) "PtdIns-4-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.67"^^xsd:string) "PI4K-alpha activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.67"^^xsd:string) Annotation( "RHEA:19880"^^xsd:string) "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = 1-phosphatidyl-1D-myo-inositol 4-phosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.67"^^xsd:string) "type II phosphatidylinositol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.67"^^xsd:string) "PI 4-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.67"^^xsd:string) "ATP:1-phosphatidyl-1D-myo-inositol 4-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.67"^^xsd:string) "phosphatidylinositol kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.67"^^xsd:string) "PI4K"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.67"^^xsd:string) "PI4-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.67"^^xsd:string) "phosphatidylinositol 4-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidylinositol phospholipase C activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.11"^^xsd:string) "1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.11"^^xsd:string) "phosphoinositidase C activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.11"^^xsd:string) "monophosphatidylinositol phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.11"^^xsd:string) Annotation( "RHEA:23915"^^xsd:string) "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H(+)."^^xsd:string) AnnotationAssertion( "phosphatidylinositol-4,5-bisphosphate hydrolysis"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.11"^^xsd:string) "PI-PLC activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.11"^^xsd:string) "1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity"^^xsd:string) AnnotationAssertion( "1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.11"^^xsd:string) "phosphoinositide phospholipase C activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.11"^^xsd:string) "triphosphoinositide phosphodiesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.6.1.13"^^xsd:string) "1-phosphatidyl-D-myo-inositol inositolphosphohydrolase (cyclic-phosphate-forming)"^^xsd:string) AnnotationAssertion( "1-phosphatidylinositol phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.13"^^xsd:string) "1-phosphatidyl-1D-myo-inositol diacyl-sn-glycerol-lyase (1D-myo-inositol-1,2-cyclic-phosphate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.13"^^xsd:string) "1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.13"^^xsd:string) "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol = D-myo-inositol 1,2-cyclic phosphate + diacylglycerol."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol diacylglycerol-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.13"^^xsd:string) "monophosphatidylinositol phosphodiesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.64"^^xsd:string) "D-myo-inositol-1,3-bisphosphate 3-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.64"^^xsd:string) "inositol-polyphosphate 3-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.64"^^xsd:string) "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O = 1-phosphatidyl-1D-myo-inositol + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.64"^^xsd:string) "1-phosphatidyl-1D-myo-inositol-3-phosphate 3-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.64"^^xsd:string) "phosphatidyl-3-phosphate 3-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.64"^^xsd:string) "inositol 1,3-bisphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.64"^^xsd:string) "inositol-1,3-bisphosphate 3-phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol-3-phosphatase activity"^^xsd:string) AnnotationAssertion( "inositol-1,4,-bisphosphate 3-phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.36"^^xsd:string) "PtdIns(4,5)P2 phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.36"^^xsd:string) Annotation( "RHEA:22767"^^xsd:string) "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.36"^^xsd:string) "triphosphoinositide phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.36"^^xsd:string) "phosphatidylinositol-bisphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.36"^^xsd:string) "triphosphoinositide phosphomonoesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.36"^^xsd:string) "phosphatidyl-myo-inositol-4,5-bisphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.36"^^xsd:string) "PtdIns(4,5)P(2) phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.36"^^xsd:string) "phosphatidylinositol 4,5-bisphosphate phosphatase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.57"^^xsd:string) "inositol polyphosphate 1-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.57"^^xsd:string) Annotation( "GOC:hb"^^xsd:string) "Catalysis of the reaction: 1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.57"^^xsd:string) "inositol-polyphosphate 1-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.57"^^xsd:string) "1D-myo-inositol-1,4-bisphosphate 1-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol-1,4-bisphosphate 1-phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "inositol 1,4,5-trisphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "inositol phosphate 5-phosphomonoesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "InsP(3)/Ins(1,3,4,5)P(4) 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "inositol trisphosphate phosphomonoesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "Ins(1,4,5)P(3) 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "inosine triphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "inositol polyphosphate-5-phosphatase activity"^^xsd:string) AnnotationAssertion( "inositol triphosphate 5-phosphomonoesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "D-myo-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "D-myo-inositol 1,4,5-trisphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "InsP3/Ins(1,3,4,5)P4 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "Ins(1,4,5)P3/Ins(1,3,4,5)P4 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "5PTase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate."^^xsd:string) AnnotationAssertion( "type II inositol-1,4,5-trisphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "type I inositol-polyphosphate phosphatase activity"^^xsd:string) AnnotationAssertion( "inositol-1,4,5-trisphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion( "type II inositol polyphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "D-myo-inositol 1,4,5-triphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "L-myo-inositol 1,4,5-trisphosphate-monoesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "inositol-1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "Ins(1,4,5)P3 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "myo-inositol-1,4,5-trisphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol-polyphosphate 5-phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol-hexakisphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.62"^^xsd:string) "MIPP activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.62"^^xsd:string) "inositol tetrakisphosphate phosphomonoesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.62"^^xsd:string) "multiple inositol-polyphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.62"^^xsd:string) "1D-myo-inositol-hexakisphosphate 5-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.62"^^xsd:string) "Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol pentakisphosphate (mixed isomers) + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.11.1.8"^^xsd:string) "tyrosine iodinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.8"^^xsd:string) "iodotyrosine deiodinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.8"^^xsd:string) "thyroperoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.8"^^xsd:string) "iodotyrosine deiodase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.8"^^xsd:string) "thyroid peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.8"^^xsd:string) "monoiodotyrosine deiodinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.8"^^xsd:string) "Catalysis of the reaction: iodide + hydrogen peroxide = iodine + 2 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.8"^^xsd:string) "iodide peroxidase-tyrosine iodinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.8"^^xsd:string) "iodoperoxidase (heme type)"^^xsd:string) AnnotationAssertion(rdfs:label "iodide peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.8"^^xsd:string) "TPO activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.8"^^xsd:string) "iodinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.8"^^xsd:string) "iodide:hydrogen-peroxide oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.-"^^xsd:string) "IDP3"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.41"^^xsd:string) Annotation( "EC:1.1.1.42"^^xsd:string) "Catalysis of the reaction: isocitrate + acceptor = 2-oxoglutarate + CO2 + reduced acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "isocitrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.-"^^xsd:string) "oxalosuccinate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.-"^^xsd:string) "isocitric acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.-"^^xsd:string) "IDP activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.-"^^xsd:string) "isocitric dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.-"^^xsd:string) "beta-ketoglutaric-isocitric carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.-"^^xsd:string) "oxalsuccinic decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.-"^^xsd:string) "IDP1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.-"^^xsd:string) "IDH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.-"^^xsd:string) "oxalosuccinate carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.-"^^xsd:string) "IDP2"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.41"^^xsd:string) "isocitrate:NAD+ oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.41"^^xsd:string) "NAD isocitric dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "isocitrate dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.41"^^xsd:string) "NAD-specific isocitrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.41"^^xsd:string) "NAD-linked isocitrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.41"^^xsd:string) "isocitrate dehydrogenase (NAD) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.41"^^xsd:string) "nicotinamide adenine dinucleotide isocitrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.41"^^xsd:string) "NAD dependent isocitrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.41"^^xsd:string) "Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.41"^^xsd:string) "NAD isocitrate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.42"^^xsd:string) "NADP-dependent isocitrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.42"^^xsd:string) "NADP(+)-ICDH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.42"^^xsd:string) "isocitrate:NADP+ oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.42"^^xsd:string) "isocitrate dehydrogenase (NADP-dependent) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.42"^^xsd:string) "NADP-linked isocitrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.42"^^xsd:string) "isocitrate dehydrogenase (NADP) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.42"^^xsd:string) "isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.42"^^xsd:string) "isocitrate (NADP) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.42"^^xsd:string) "NADP-dependent isocitric dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.42"^^xsd:string) "NADP isocitric dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.42"^^xsd:string) "Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.42"^^xsd:string) "NADP-specific isocitrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.42"^^xsd:string) "dual-cofactor-specific isocitrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.42"^^xsd:string) "triphosphopyridine nucleotide-linked isocitrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.42"^^xsd:string) "NADP(+)-IDH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.42"^^xsd:string) "NADP(+)-linked isocitrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "isocitrate dehydrogenase (NADP+) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3.1"^^xsd:string) "threo-DS-isocitrate glyoxylate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.1"^^xsd:string) "isocitritase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.1"^^xsd:string) "isocitratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.1"^^xsd:string) "ICL activity"^^xsd:string) AnnotationAssertion(rdfs:label "isocitrate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.1"^^xsd:string) "isocitrate glyoxylate-lyase (succinate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.1"^^xsd:string) "isocitrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.1"^^xsd:string) Annotation( "RHEA:13248"^^xsd:string) "Catalysis of the reaction: isocitrate = glyoxylate + succinate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.1"^^xsd:string) "isocitrate glyoxylate-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.3.2"^^xsd:string) "methylbutenylpyrophosphate isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "isopentenyl-diphosphate delta-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.2"^^xsd:string) "IPP isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.2"^^xsd:string) "isopentenyl-diphosphate delta3-delta2-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.2"^^xsd:string) Annotation( "RHEA:23287"^^xsd:string) "Catalysis of the reaction: isopentenyl diphosphate = dimethylallyl diphosphate."^^xsd:string) AnnotationAssertion( "isopentenyl-diphosphate D-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.2"^^xsd:string) "isopentenylpyrophosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.2"^^xsd:string) "isopentenylpyrophosphate delta-isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.59"^^xsd:string) Annotation( "EMBL:AF304352"^^xsd:string) "Catalysis of the reaction: methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + H2O = (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + methanol. A carboxylesterase that hydrolyzes the ester linkage of juvenile hormone."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.59"^^xsd:string) "JH esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.59"^^xsd:string) "methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "juvenile-hormone esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.59"^^xsd:string) "JH-esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.59"^^xsd:string) "juvenile hormone carboxyesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.59"^^xsd:string) "juvenile hormone analog esterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ketohexokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.3"^^xsd:string) "Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.3"^^xsd:string) "ATP:D-fructose 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.3"^^xsd:string) "hepatic fructokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.3"^^xsd:string) "ketohexokinase (phosphorylating)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.86"^^xsd:string) "Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.86"^^xsd:string) "acetohydroxy acid reductoisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.86"^^xsd:string) "isomeroreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.86"^^xsd:string) "(R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.86"^^xsd:string) "alpha-keto-beta-hydroxylacyl reductoisomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ketol-acid reductoisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.86"^^xsd:string) "reductoisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.86"^^xsd:string) "dihydroxyisovalerate (isomerizing) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.86"^^xsd:string) "acetohydroxy acid isomeroreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.86"^^xsd:string) "ketol acid reductoisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.86"^^xsd:string) "2-hydroxy-3-keto acid reductoisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.86"^^xsd:string) "dihydroxyisovalerate dehydrogenase (isomerizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.86"^^xsd:string) "acetolactate reductoisomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.12"^^xsd:string) "6-phosphogluconic dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.12"^^xsd:string) "6-phospho-D-gluconate hydro-lyase (2-dehydro-3-deoxy-6-phospho-D-gluconate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.12"^^xsd:string) "6-phospho-D-gluconate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.12"^^xsd:string) "gluconate-6-phosphate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.12"^^xsd:string) "6-phosphogluconate dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.12"^^xsd:string) "gluconate 6-phosphate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.12"^^xsd:string) "6-phosphogluconate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.12"^^xsd:string) Annotation( "RHEA:17280"^^xsd:string) "Catalysis of the reaction: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H(2)O."^^xsd:string) AnnotationAssertion(rdfs:label "phosphogluconate dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lactate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) "Catalysis of the reaction: lactate + NAD+ = H+ + NADH + pyruvate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.2.4"^^xsd:string) "D-lactate (cytochrome) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.4"^^xsd:string) "cytochrome-dependent D-(-)-lactate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.4"^^xsd:string) "lactic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.4"^^xsd:string) "(R)-lactate:ferricytochrome-c 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.4"^^xsd:string) "D-lactate ferricytochrome c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.4"^^xsd:string) "D-(-)-lactic cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.4"^^xsd:string) "Catalysis of the reaction: (R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c."^^xsd:string) AnnotationAssertion(rdfs:label "D-lactate dehydrogenase (cytochrome) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.4"^^xsd:string) "D-lactate-cytochrome c reductase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.27"^^xsd:string) "L-lactic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.27"^^xsd:string) "L-lactic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.27"^^xsd:string) Annotation( "RHEA:23447"^^xsd:string) "Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "L-lactate dehydrogenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.2.3"^^xsd:string) "lactate dehydrogenase (cytochrome)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.3"^^xsd:string) "L-lactate cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.3"^^xsd:string) "lactic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.3"^^xsd:string) "dehydrogenase, lactate (cytochrome)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.3"^^xsd:string) "flavocytochrome b2"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.3"^^xsd:string) "(S)-lactate:ferricytochrome-c 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.3"^^xsd:string) "L-lactate ferricytochrome c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.3"^^xsd:string) "cytochrome b2 (flavin-free derivative of flavocytochrome b2)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.3"^^xsd:string) "L-lactate cytochrome c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.3"^^xsd:string) "L(+)-lactate:cytochrome c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.3"^^xsd:string) "lactic cytochrome c reductase activity"^^xsd:string) AnnotationAssertion( "cytochrome b2"^^xsd:string) AnnotationAssertion(rdfs:label "L-lactate dehydrogenase (cytochrome) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.3"^^xsd:string) "Catalysis of the reaction: (S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.22"^^xsd:string) "UDPgalactose-glucose galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.22"^^xsd:string) "UDPgalactose:D-glucose 4-beta-D-galactotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.22"^^xsd:string) "lactose synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.22"^^xsd:string) "Catalysis of the reaction: UDP-galactose + D-glucose = UDP + lactose."^^xsd:string) AnnotationAssertion(rdfs:label "lactose synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.22"^^xsd:string) "UDP-galactose-glucose galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.22"^^xsd:string) "UDP-galactose:D-glucose 4-beta-D-galactotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.22"^^xsd:string) "uridine diphosphogalactose-glucose galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.5"^^xsd:string) "ketone-aldehyde mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.5"^^xsd:string) "glyoxylase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.5"^^xsd:string) "methylglyoxalase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.5"^^xsd:string) "glyoxalase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.5"^^xsd:string) Annotation( "RHEA:19072"^^xsd:string) "Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal."^^xsd:string) AnnotationAssertion(rdfs:label "lactoylglutathione lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.5"^^xsd:string) "aldoketomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.5"^^xsd:string) "(R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing; glutathione-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.5"^^xsd:string) "(R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.3.2.6"^^xsd:string) "LTA-4 hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.6"^^xsd:string) Annotation( "RHEA:22327"^^xsd:string) "Catalysis of the reaction: H(2)O + leukotriene A(4) = leukotriene B(4)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.6"^^xsd:string) "LTA4 hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.6"^^xsd:string) "(7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.6"^^xsd:string) "leukotriene A(4) hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "leukotriene-A4 hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.6"^^xsd:string) "leukotriene A4 hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.6"^^xsd:string) "LTA4H"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.20"^^xsd:string) "leukotriene A(4):glutathione S-leukotrienyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.20"^^xsd:string) "leukotriene-C4 glutathione-lyase (leukotriene-A4-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.20"^^xsd:string) "leukotriene A4:glutathione S-leukotrienyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.20"^^xsd:string) "leukotriene C(4) synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.20"^^xsd:string) "(7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase (epoxide-ring-opening)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.20"^^xsd:string) "(7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.20"^^xsd:string) "LTC4 synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.20"^^xsd:string) Annotation( "RHEA:17620"^^xsd:string) "Catalysis of the reaction: leukotriene C(4) = glutathione + leukotriene A(4)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.20"^^xsd:string) "LTC(4) synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.20"^^xsd:string) "LTC4 synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.20"^^xsd:string) "LTC(4) synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.20"^^xsd:string) "leukotriene C4 synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "leukotriene-C4 synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lipoprotein lipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.34"^^xsd:string) "diacylglycerol hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.34"^^xsd:string) "lipemia-clearing factor"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.34"^^xsd:string) "postheparin esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.34"^^xsd:string) "diacylglycerol lipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.34"^^xsd:string) "clearing factor lipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.34"^^xsd:string) "postheparin lipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.34"^^xsd:string) "diglyceride lipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.34"^^xsd:string) "triacylglycero-protein acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.34"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) "Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate, where the triacylglycerol is part of a lipoprotein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.99.13"^^xsd:string) "palmitoyl-coenzyme A dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.13"^^xsd:string) "palmitoyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "long-chain-acyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.13"^^xsd:string) "long-chain-acyl-CoA:acceptor 2,3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.13"^^xsd:string) "long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.13"^^xsd:string) "Catalysis of the reaction: acyl-CoA + ETF = 2,3-dehydroacyl-CoA + reduced ETF."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.13"^^xsd:string) "long-chain acyl-coenzyme A dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "long-chain acyl-CoA synthetase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "ACS3"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "fatty acid thiokinase (long chain) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "FAA1"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "long chain fatty acyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "oleoyl-CoA synthetase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "LCFA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "acyl-activating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "palmitoyl-CoA ligase"^^xsd:string) AnnotationAssertion( "long-chain-fatty-acyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "long-chain fatty acyl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion( "long-chain acyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "stearoyl-CoA synthetase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "long-chain acyl CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "lignoceroyl-CoA synthase activity"^^xsd:string) AnnotationAssertion( "long-chain fatty acid activation"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "palmitoyl coenzyme A synthetase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "pristanoyl-CoA synthetase"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15904"^^xsd:string) Annotation( "EC:6.2.1.3"^^xsd:string) "Catalysis of the reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a long-chain fatty acid is a fatty acid with a chain length between C13 and C22."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "thiokinase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "arachidonyl-CoA synthetase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "fatty acid thiokinase (long-chain) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "palmitoyl-CoA synthase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "long-chain acyl-CoA synthetase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "long-chain acyl-coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "long-chain fatty acid-CoA ligase activity"^^xsd:string) AnnotationAssertion( "long-chain-fatty-acid-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "acyl-CoA synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.32"^^xsd:string) "Catalysis of the reaction: acetyl phosphate + L-lysine = phosphate + N6-acetyl-L-lysine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.32"^^xsd:string) "lysine N6-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.32"^^xsd:string) "acetyl-phosphate:L-lysine N6-acetyltransferase activity"^^xsd:string) AnnotationAssertion( "lysine acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.32"^^xsd:string) "LAT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.32"^^xsd:string) "acetyl-phosphate:L-lysine 6-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lysine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.32"^^xsd:string) "lysine N(6)-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the oxidative decarboxylation of malate with the concomitant production of pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.39"^^xsd:string) "pyruvic-malic carboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "malic enzyme activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.38"^^xsd:string) "NAD-linked malic enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.39"^^xsd:string) "malate dehydrogenase (decarboxylating) activity"^^xsd:string) AnnotationAssertion( "malate dehydrogenase (oxaloacetate-decarboxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.38"^^xsd:string) Annotation( "EC:1.1.1.39"^^xsd:string) "NAD-specific malic enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.38"^^xsd:string) "(S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.38"^^xsd:string) Annotation( "EC:1.1.1.39"^^xsd:string) "NAD-malic enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.39"^^xsd:string) "(S)-malate:NAD+ oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.38"^^xsd:string) Annotation( "EC:1.1.1.39"^^xsd:string) "Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.38"^^xsd:string) Annotation( "EC:1.1.1.39"^^xsd:string) "'malic' enzyme"^^xsd:string) AnnotationAssertion(rdfs:label "malate dehydrogenase (decarboxylating) (NAD+) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.40"^^xsd:string) "L-malate:NADP oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "malate dehydrogenase (decarboxylating) (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.40"^^xsd:string) "'malic' enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.40"^^xsd:string) "NADP-specific malate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.40"^^xsd:string) "malate dehydrogenase (decarboxylating, NADP)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.40"^^xsd:string) "NADP-specific malic enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.40"^^xsd:string) "Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.40"^^xsd:string) "(S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.40"^^xsd:string) "NADP-malic enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.40"^^xsd:string) "NADP-linked decarboxylating malic enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.40"^^xsd:string) "malate dehydrogenase (NADP, decarboxylating)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.3.9"^^xsd:string) "glyoxylate transacetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.9"^^xsd:string) "acetyl-CoA:glyoxylate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.9"^^xsd:string) "malic-condensing enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.9"^^xsd:string) "L-malate glyoxylate-lyase (CoA-acetylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.9"^^xsd:string) "malic synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.9"^^xsd:string) "glyoxylate transacetylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "malate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.9"^^xsd:string) "malate condensing enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.9"^^xsd:string) "glyoxylic transacetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.9"^^xsd:string) "malate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.9"^^xsd:string) Annotation( "RHEA:18184"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + glyoxylate + H(2)O = (S)-malate + CoA + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.13"^^xsd:string) "GTP:alpha-D-mannose-1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.13"^^xsd:string) "PIM-GMP (phosphomannose isomerase-guanosine 5'-diphospho-D-mannose pyrophosphorylase)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.13"^^xsd:string) "GDP-mannose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion( "GTP:mannose-1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.13"^^xsd:string) "guanosine triphosphate-mannose 1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannose-1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.13"^^xsd:string) Annotation( "RHEA:15232"^^xsd:string) "Catalysis of the reaction: alpha-D-mannose 1-phosphate + GTP = diphosphate + GDP-alpha-D-mannose."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.13"^^xsd:string) "mannose 1-phosphate guanylyltransferase (guanosine triphosphate)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.13"^^xsd:string) "guanosine diphosphomannose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.13"^^xsd:string) "guanosine 5'-diphospho-D-mannose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.13"^^xsd:string) "GTP-mannose-1-phosphate guanylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.1.8"^^xsd:string) "D-mannose-6-phosphate ketol-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.8"^^xsd:string) "D-mannose-6-phosphate aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.8"^^xsd:string) "phosphomannose isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.8"^^xsd:string) "phosphohexomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.8"^^xsd:string) "phosphomannoisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.8"^^xsd:string) "Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.8"^^xsd:string) "mannose phosphate isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannose-6-phosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.8"^^xsd:string) "phosphohexoisomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.9"^^xsd:string) "formyl-methenyl-methylenetetrahydrofolate synthetase (combined)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.9"^^xsd:string) "Catalysis of the reaction: 5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate."^^xsd:string) AnnotationAssertion(rdfs:label "methenyltetrahydrofolate cyclohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) "5,10-methenyl-THF cyclohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.9"^^xsd:string) "5,10-methenyltetrahydrofolate 5-hydrolase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.9"^^xsd:string) "citrovorum factor cyclodehydrase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.6"^^xsd:string) "ATP:L-methionine S-adenosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.6"^^xsd:string) "ATP-methionine adenosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.6"^^xsd:string) "Catalysis of the reaction: ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.6"^^xsd:string) "methionine S-adenosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.6"^^xsd:string) "S-adenosyl-L-methionine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.6"^^xsd:string) "AdoMet synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.6"^^xsd:string) "adenosylmethionine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.6"^^xsd:string) "S-adenosylmethionine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.6"^^xsd:string) "S-adenosylmethionine synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methionine adenosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.6"^^xsd:string) "methionine-activating enzyme"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.2.9"^^xsd:string) "formylmethionyl-transfer ribonucleic synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "GO:curators"^^xsd:string) "conversion of mitochondrial met-tRNAf to fmet-tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GO:curators"^^xsd:string) "mitochondrial N-terminal peptidyl-methionine N-formylation"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.9"^^xsd:string) "methionyl-transfer RNA transformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.9"^^xsd:string) "N(10)-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.9"^^xsd:string) "methionyl ribonucleic formyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.9"^^xsd:string) "methionyl-transfer ribonucleic transformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.9"^^xsd:string) "N10-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.9"^^xsd:string) "Catalysis of the reaction: 10-formyltetrahydrofolate + L-methionyl-tRNA + H2O = tetrahydrofolate + N-formylmethionyl-tRNA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.9"^^xsd:string) "methionyl-tRNA transformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.9"^^xsd:string) "methionyl-tRNA Met formyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methionyl-tRNA formyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GO:curators"^^xsd:string) "N-terminal peptidyl-methionine N-formylation"^^xsd:string) AnnotationAssertion(Annotation( "GO:curators"^^xsd:string) "conversion of met-tRNAf to fmet-tRNA"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.9"^^xsd:string) "10-formyltetrahydrofolate:L-methionyl-tRNA N-formyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.9"^^xsd:string) "methionyl-transfer ribonucleate methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.16"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid methylene fatty acid."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.16"^^xsd:string) "S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (methenylating)"^^xsd:string) AnnotationAssertion(rdfs:label "methylene-fatty-acyl-phospholipid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.16"^^xsd:string) "cyclopropane synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.16"^^xsd:string) "unsaturated-phospholipid methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.56"^^xsd:string) "S-adenosyl-L-methionine:mRNA (guanine-7-N-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.56"^^xsd:string) "guanine-7-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.56"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA. m7G(5')pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.56"^^xsd:string) "S-adenosyl-L-methionine:mRNA (guanine-N7-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.56"^^xsd:string) "messenger ribonucleate guanine 7-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.56"^^xsd:string) "messenger RNA guanine 7-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mRNA (guanine-N7-)-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mRNA (nucleoside-2'-O-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.57"^^xsd:string) "mRNA (adenosine-2'-O-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.57"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + m7G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA. R may be guanosine or adenosine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.57"^^xsd:string) "S-adenosyl-L-methionine:mRNA (nucleoside-2'-O-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.57"^^xsd:string) "messenger RNA (nucleoside-2'-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.57"^^xsd:string) "messenger ribonucleate nucleoside 2'-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "GTP:mRNA guanylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mRNA guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.50"^^xsd:string) "Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.50"^^xsd:string) "mRNA capping enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.50"^^xsd:string) "protein lambda2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.50"^^xsd:string) "messenger RNA guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.50"^^xsd:string) "GTP--RNA guanylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.4.1.4"^^xsd:string) "beta-methylcrotonyl coenzyme A carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.4"^^xsd:string) "beta-methylcrotonyl-CoA carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.4"^^xsd:string) "methylcrotonyl-CoA carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.4"^^xsd:string) "methylcrotonyl coenzyme A carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.4"^^xsd:string) "beta-methylcrotonyl CoA carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.4"^^xsd:string) "3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "methylcrotonoyl-CoA carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.4"^^xsd:string) Annotation( "RHEA:13592"^^xsd:string) "Catalysis of the reaction: 3-methylbut-2-enoyl-CoA + ATP + bicarbonate = trans-3-methylglutaconyl-CoA + ADP + 2 H(+) + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) "5,10-methylene-THF dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.5"^^xsd:string) "N5,N10-methylenetetrahydrofolate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.-"^^xsd:string) Annotation( "EC:1.5.1.15"^^xsd:string) "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(P)+ = 5,10-methenyltetrahydrofolate + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(rdfs:label "methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methylenetetrahydrofolate dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.15"^^xsd:string) "5,10-methylenetetrahydrofolate:NAD+ oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.15"^^xsd:string) Annotation( "RHEA:22895"^^xsd:string) "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(+) = 5,10-methenyltetrahydrofolate + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.5"^^xsd:string) "5,10-methylenetetrahydrofolate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.5"^^xsd:string) Annotation( "RHEA:22815"^^xsd:string) "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.5"^^xsd:string) "5,10-methylenetetrahydrofolate:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methylenetetrahydrofolate dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.5"^^xsd:string) "5,10-methylenetetrahydrofolate:NADP oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "N5,10-methylenetetrahydrofolate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "5,10-methylenetetrahydrofolate reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "5-methyltetrahydrofolate:(acceptor) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "5,10-methylenetetrahydropteroylglutamate reductase activity"^^xsd:string) AnnotationAssertion( "5,10-methylenetetrahydrofolate reductase (FADH2) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "methylenetetrahydrofolate reductase (NADPH(2)) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "5,10-CH2-H4folate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "5,10-CH(2)-H(4)folate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "methylenetetrahydrofolic acid reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "5-methyltetrahydrofolate:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "N(5),N(10)-methylenetetrahydrofolate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "methylenetetrahydrofolate reductase activity"^^xsd:string) AnnotationAssertion( "1.7.99.5"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "5-methyltetrahydrofolate:NAD(+) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "5-methyltetrahydrofolate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "N(5,10)-methylenetetrahydrofolate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "5,10-methylenetetrahydrofolate reductase (FADH(2)) activity"^^xsd:string) AnnotationAssertion( "5,10-methylenetetrahydrofolate reductase (FADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "MTHFR activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "5-methyltetrahydrofolate:NADP(+) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "MetF"^^xsd:string) AnnotationAssertion(rdfs:label "methylenetetrahydrofolate reductase (NAD(P)H) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "5-methyltetrahydrofolate:NAD oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "5,10-methylenetetrahydrofolic acid reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "methylenetetrahydrofolate reductase (NADPH2)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "methylenetetrahydrofolate reductase [NAD(P)H]"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "N5,N10-methylenetetrahydrofolate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.20"^^xsd:string) "5,10-methylenetetrahydrofolate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methylglutaconyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.18"^^xsd:string) "(S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase (trans-3-methylglutaconyl-CoA-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.18"^^xsd:string) "methylglutaconyl coenzyme A hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.18"^^xsd:string) "3-methylglutaconyl CoA hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.18"^^xsd:string) Annotation( "RHEA:21539"^^xsd:string) "Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = trans-3-methylglutaconyl-CoA + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.18"^^xsd:string) "(S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.18"^^xsd:string) "methylglutaconase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.27"^^xsd:string) "2-methyl-3-oxopropanoate:NAD+ 3-oxidoreductase (CoA-propanoylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.27"^^xsd:string) "MSDH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.27"^^xsd:string) "MMSA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.27"^^xsd:string) "Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + CO2 + NADH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "methylmalonate-semialdehyde dehydrogenase (acylating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.41"^^xsd:string) "(S)-2-methyl-3-oxopropanoyl-CoA carboxy-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methylmalonyl-CoA decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.41"^^xsd:string) "(S)-methylmalonyl-CoA carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.41"^^xsd:string) "Catalysis of the reaction: (S)-2-methyl-3-oxopropanoyl-CoA = propanoyl-CoA + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.41"^^xsd:string) "(S)-methylmalonyl-CoA carboxy-lyase (propanoyl-CoA-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.41"^^xsd:string) "methylmalonyl-coenzyme A decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.99.1"^^xsd:string) "methylmalonyl-CoA 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.99.1"^^xsd:string) Annotation( "RHEA:20556"^^xsd:string) "Catalysis of the reaction: (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.99.1"^^xsd:string) "DL-methylmalonyl-CoA racemase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methylmalonyl-CoA epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.99.1"^^xsd:string) "methylmalonyl-CoA racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.99.1"^^xsd:string) "2-methyl-3-oxopropanoyl-CoA 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.99.1"^^xsd:string) "methylmalonyl coenzyme A racemase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.99.2"^^xsd:string) Annotation( "RHEA:22891"^^xsd:string) "Catalysis of the reaction: (R)-methylmalonyl-CoA = succinyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "methylmalonyl-CoA mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.2"^^xsd:string) "(S)-methylmalonyl-CoA mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.2"^^xsd:string) "(R)-2-methyl-3-oxopropanoyl-CoA CoA-carbonylmutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.2"^^xsd:string) "methylmalonyl coenzyme A carbonylmutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.2"^^xsd:string) "methylmalonyl-CoA CoA-carbonyl mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.2"^^xsd:string) "(R)-methylmalonyl-CoA CoA-carbonylmutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.2"^^xsd:string) "methylmalonyl coenzyme A mutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.32"^^xsd:string) Annotation( "EC:1.1.1.33"^^xsd:string) "Catalysis of the reaction: (R)-mevalonate + acceptor = mevaldate + reduced acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "mevaldate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.36"^^xsd:string) "mevalonic acid kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.36"^^xsd:string) "MVA kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.36"^^xsd:string) "mevalonate phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.36"^^xsd:string) "mevalonic kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.36"^^xsd:string) "ATP:(R)-mevalonate 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.36"^^xsd:string) Annotation( "RHEA:17068"^^xsd:string) "Catalysis of the reaction: (R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.36"^^xsd:string) "mevalonate 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.36"^^xsd:string) "ATP:mevalonate 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.36"^^xsd:string) "mevalonate kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "mevalonate kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "http://www.onelook.com/"^^xsd:string) "Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cytochrome P450 CYP27B"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.13"^^xsd:string) "25-hydroxy D3-1alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.13"^^xsd:string) "1-hydroxylase-25-hydroxyvitamin D3 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.13"^^xsd:string) "calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.13"^^xsd:string) "25-OHD-1 alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.13"^^xsd:string) "25-hydroxyvitamin D3 1alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.13"^^xsd:string) "25-hydroxycholecalciferol 1-monooxygenase activity"^^xsd:string) AnnotationAssertion( "25-hydroxy vitamin D3 1-alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.13"^^xsd:string) "25-hydroxyvitamin D-1 alpha hydroxylase activity"^^xsd:string) AnnotationAssertion( "25-hydroxycholecalciferol 1-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.13"^^xsd:string) Annotation( "RHEA:20576"^^xsd:string) "Catalysis of the reaction: calcidiol + H(+) + NADPH + O(2) = calcitriol + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(rdfs:label "calcidiol 1-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.13"^^xsd:string) "25-hydroxycholecalciferol-1-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.13"^^xsd:string) "25-hydroxycholecalciferol 1alpha-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "flavin monooxygenase activity"^^xsd:string) AnnotationAssertion( "methylphenyltetrahydropyridine N-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "FMO2"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "FAD-containing monooxygenase activity"^^xsd:string) AnnotationAssertion( "dimethylaniline monooxygenase (N-oxide-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "FMO-I"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "flavin mixed function oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "FMO5"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "FMO activity"^^xsd:string) AnnotationAssertion(rdfs:label "N,N-dimethylaniline monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "FMO4"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "N,N-dimethylaniline,NADPH:oxygen oxidoreductase (N-oxide-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "mixed-function amine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "dimethylaniline oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine:oxygen N-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "flavin-containing monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "FMO-II"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "DMA oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "FMO1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.8"^^xsd:string) "Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "FMO3"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "dimethylaniline N-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.11"^^xsd:string) "Ziegler's enzyme"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.17.1"^^xsd:string) "dopa beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.1"^^xsd:string) "dopamine beta-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.1"^^xsd:string) "MDBH (membrane-associated dopamine beta-monooxygenase)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.1"^^xsd:string) "3,4-dihydroxyphenethylamine beta-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.1"^^xsd:string) "4-(2-aminoethyl)pyrocatechol beta-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.1"^^xsd:string) "3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.1"^^xsd:string) "SDBH (soluble dopamine beta-monooxygenase)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.1"^^xsd:string) "oxygenase, dopamine beta-mono-"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.1"^^xsd:string) "dopamine-B-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.1"^^xsd:string) Annotation( "RHEA:19120"^^xsd:string) "Catalysis of the reaction: L-ascorbate + dopamine + O(2) = (R)-noradrenaline + dehydroascorbate + H(2)O."^^xsd:string) AnnotationAssertion( "dopamine b-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.1"^^xsd:string) "(3,4-dihydroxyphenethylamine)beta-mono-oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.1"^^xsd:string) "phenylamine beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dopamine beta-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.1"^^xsd:string) "dopamine beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.1"^^xsd:string) "dopamine hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ecdysone 20-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ecdysone 20-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.22"^^xsd:string) Annotation( "RHEA:14024"^^xsd:string) "Catalysis of the reaction: AH(2) + Ecdysone + O(2) = 20-hydroxyecdysone + A + H(2)O."^^xsd:string) AnnotationAssertion( "ecdysone modification"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.22"^^xsd:string) "alpha-ecdysone C-20 hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.22"^^xsd:string) "ecdysone,hydrogen-donor:oxygen oxidoreductase (20-hydroxylating)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "kynurenine 3-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.9"^^xsd:string) "L-kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.9"^^xsd:string) "L-kynurenine-3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.9"^^xsd:string) Annotation( "RHEA:20548"^^xsd:string) "Catalysis of the reaction: L-kynurenine + H(+) + NADPH + O(2) = 3-hydroxy-L-kynurenine + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion( "kynurenine 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.9"^^xsd:string) "kynurenine hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "chlorogenic acid oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "tyrosinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "polyphenolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) "prophenol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "o-diphenol:O2 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "monophenol monooxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "cresolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "chlorogenic oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "o-diphenol:oxygen oxidoreductase"^^xsd:string) AnnotationAssertion( "prophenoloxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "pyrocatechol oxidase"^^xsd:string) AnnotationAssertion( "phenol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "monophenol dihydroxyphenylalanine:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:2494997"^^xsd:string) "monophenol oxygenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "catecholase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "phenolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "monophenol, dihydroxy-L-phenylalanine oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "L-tyrosine monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "monophenol monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "o-diphenol oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "tyrosine-dopa oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "o-diphenol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "polyaromatic oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "monophenolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "monophenol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "monophenol,L-dopa:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:4965136"^^xsd:string) "Catalysis of the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "N-acetyl-6-hydroxytryptophan oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.1"^^xsd:string) "dopa oxidase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "peptidylglycine 2-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.3"^^xsd:string) "PAM-B"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.3"^^xsd:string) "peptide-alpha-amide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.3"^^xsd:string) "peptidylglycine,ascorbate:oxygen oxidoreductase (2-hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "peptidylglycine monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.3"^^xsd:string) "peptidylglycine alpha-amidating monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.3"^^xsd:string) "PAM-A"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.3"^^xsd:string) "peptidylglycine alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.3"^^xsd:string) "Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.3"^^xsd:string) "PAM activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.3"^^xsd:string) "peptide alpha-amide synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.3"^^xsd:string) "peptidyl alpha-amidating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.3"^^xsd:string) "peptide alpha-amidating enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.3"^^xsd:string) "synthase, peptide alpha-amide"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.16.1"^^xsd:string) "PAH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.1"^^xsd:string) "phenylalaninase activity"^^xsd:string) AnnotationAssertion( "phenylalanine hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.1"^^xsd:string) "L-phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.1"^^xsd:string) "phenylalanine 4-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.1"^^xsd:string) "Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin."^^xsd:string) AnnotationAssertion(rdfs:label "phenylalanine 4-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "RHEA:25285"^^xsd:string) "Catalysis of the reaction: H(+) + NADPH + O(2) + squalene = (S)-2,3-epoxysqualene + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.132"^^xsd:string) "squalene hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R02874"^^xsd:string) "squalene,NADPH:oxygen oxidoreductase (2,3-epoxidizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.132"^^xsd:string) "squalene 2,3-oxidocyclase activity"^^xsd:string) AnnotationAssertion(rdfs:label "squalene monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.132"^^xsd:string) "squalene-2,3-epoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.132"^^xsd:string) "squalene epoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.132"^^xsd:string) "squalene-2,3-epoxide cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.132"^^xsd:string) "squalene oxydocyclase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.15.4"^^xsd:string) "oxygenase, steroid 11beta -mono-"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.4"^^xsd:string) "steroid 11beta-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.4"^^xsd:string) "Catalysis of the reaction: a steroid + reduced adrenal ferredoxin + O2 = an 11-beta-hydroxysteroid + oxidized adrenal ferredoxin + H2O."^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP11B1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.4"^^xsd:string) "steroid 11beta-hydroxylase activity"^^xsd:string) AnnotationAssertion( "steroid 11-beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.4"^^xsd:string) "steroid,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11beta-hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "steroid 11-beta-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.4"^^xsd:string) "steroid 11beta/18-hydroxylase activity"^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP11B2"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.4"^^xsd:string) "cytochrome p450 XIB1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.4"^^xsd:string) "steroid 11-beta/18-hydroxylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "steroid 17-alpha-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.9"^^xsd:string) "cytochrome p450 XVIIA1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.9"^^xsd:string) "Catalysis of the reaction: a steroid + AH2 + O2 = a 17a-hydroxysteroid + A + H2O."^^xsd:string) AnnotationAssertion( "steroid 17-alpha-hydroxylase-C17-20 lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.9"^^xsd:string) "steroid,hydrogen-donor:oxygen oxidoreductase (17alpha-hydroxylating)"^^xsd:string) AnnotationAssertion( "steroid 17-alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.9"^^xsd:string) "steroid 17alpha-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.9"^^xsd:string) "steroid 17alphahydroxylase/17,20 lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.9"^^xsd:string) "17alpha-hydroxylase-C17,20 lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.9"^^xsd:string) "cytochrome P45017alpha"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.9"^^xsd:string) "cytochrome P-450 (P-45017alpha,lyase)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.9"^^xsd:string) "steroid 17alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.9"^^xsd:string) "steroid 17-alpha-hydroxylase/17,20 lyase activity"^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP17"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "steroid 21-monooxygenase activity"^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP21A1"^^xsd:string) AnnotationAssertion( "steroid 21-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.10"^^xsd:string) "Catalysis of the reaction: a steroid + donor-H2 + O2 = a 21-hydroxysteroid + acceptor + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.10"^^xsd:string) "cytochrome p450 XXIA1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.10"^^xsd:string) "steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.10"^^xsd:string) "21-hydroxylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.16.4"^^xsd:string) "indoleacetic acid-5-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.4"^^xsd:string) "Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.4"^^xsd:string) "tryptophan hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.4"^^xsd:string) "L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "tryptophan 5-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.4"^^xsd:string) "tryptophan 5-hydroxylase activity"^^xsd:string) AnnotationAssertion( "L-tryptophan hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "tyrosine hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tyrosine 3-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.2"^^xsd:string) "Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O."^^xsd:string) AnnotationAssertion( "tyrosine 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.2"^^xsd:string) "L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.2"^^xsd:string) "L-tyrosine hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.5.1.4"^^xsd:string) "D-glucose 6-phosphate cycloaldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.4"^^xsd:string) "1L-myo-inositol-1-phosphate lyase (isomerizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.4"^^xsd:string) "glucose 6-phosphate cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.4"^^xsd:string) "glucose-6-phosphate inositol monophosphate cycloaldolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol-3-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.4"^^xsd:string) "inositol 1-phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.4"^^xsd:string) Annotation( "RHEA:10719"^^xsd:string) "Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.4"^^xsd:string) "glucocycloaldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.4"^^xsd:string) "inositol 1-phosphate synthatase activity"^^xsd:string) AnnotationAssertion( "myo-inositol-1-phosphate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.99.10"^^xsd:string) "SAT-3"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.10"^^xsd:string) "CMP-N-acetylneuraminate:neolactotetraosylceramide alpha-2,3-sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.10"^^xsd:string) "sialyltransferase 3"^^xsd:string) AnnotationAssertion(rdfs:label "neolactotetraosylceramide alpha-2,3-sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.10"^^xsd:string) "cytidine monophosphoacetylneuraminate-neolactotetraosylceramide sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.10"^^xsd:string) "Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.19"^^xsd:string) "quinolinic acid phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.19"^^xsd:string) Annotation( "RHEA:12736"^^xsd:string) "Catalysis of the reaction: CO(2) + diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.19"^^xsd:string) "QAPRTase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nicotinate-nucleotide diphosphorylase (carboxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.19"^^xsd:string) "nicotinate mononucleotide pyrophosphorylase (carboxylating)"^^xsd:string) AnnotationAssertion( "nicotinate-nucleotide pyrophosphorylase (carboxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.19"^^xsd:string) "nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase (carboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.19"^^xsd:string) "NAD pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.19"^^xsd:string) "quinolinate phosphoribosyltransferase (decarboxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.19"^^xsd:string) "quinolinic phosphoribosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "nicotinic acid mononucleotide adenylyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.18"^^xsd:string) "deamidonicotinamide adenine dinucleotide pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.18"^^xsd:string) "deamido-NAD(+) diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.18"^^xsd:string) "nicotinate mononucleotide adenylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nicotinate-nucleotide adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.18"^^xsd:string) "Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.18"^^xsd:string) "deamido-NAD+ pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.18"^^xsd:string) "deamido-NAD(+) pyrophosphorylase activity"^^xsd:string) AnnotationAssertion( "ATP:nicotinate-nucleotide adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.18"^^xsd:string) "ATP:nicotinate-ribonucleotide adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.18"^^xsd:string) "NaMN-ATase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.11"^^xsd:string) "nicotinic acid mononucleotide glycohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.11"^^xsd:string) "nicotinic acid mononucleotide pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.11"^^xsd:string) "nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.11"^^xsd:string) "nicotinic acid phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.11"^^xsd:string) "niacin ribonucleotidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nicotinate phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.11"^^xsd:string) Annotation( "RHEA:13396"^^xsd:string) "Catalysis of the reaction: diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.39"^^xsd:string) "Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.39"^^xsd:string) "NADPH-diaphorase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.39"^^xsd:string) "nitric-oxide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.39"^^xsd:string) "L-arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.39"^^xsd:string) "NO synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.39"^^xsd:string) "endothelium-derived relaxation factor-forming enzyme activity"^^xsd:string) AnnotationAssertion( "nitric oxide synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.39"^^xsd:string) "endothelium-derived relaxing factor synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nitric-oxide synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.39"^^xsd:string) "nitric oxide synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within nucleic acids."^^xsd:string) AnnotationAssertion(rdfs:label "nuclease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks."^^xsd:string) AnnotationAssertion(rdfs:label "endonuclease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "DNA nicking activity"^^xsd:string) AnnotationAssertion(rdfs:label "endodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks."^^xsd:string) AnnotationAssertion( "endonuclease G activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "endoribonuclease activity"^^xsd:string) AnnotationAssertion( "endonuclease G activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.27.5"^^xsd:string) "Catalysis of the endonucleolytic cleavage of RNA to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in C-P or U-P with 2',3'-cyclic phosphate intermediates."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.5"^^xsd:string) "gene S glycoproteins"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.5"^^xsd:string) "ceratitis capitata alkaline ribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.5"^^xsd:string) "S-genotype-assocd. glycoproteins"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.5"^^xsd:string) "SLSG glycoproteins"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.5"^^xsd:string) "ribonucleate 3'-pyrimidino-oligonucleotidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.5"^^xsd:string) "RNase A activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.5"^^xsd:string) "pancreatic RNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.5"^^xsd:string) "ribonuclease I activity"^^xsd:string) AnnotationAssertion(rdfs:label "pancreatic ribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.5"^^xsd:string) "ribonucleic phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.5"^^xsd:string) "alkaline ribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.5"^^xsd:string) "RNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.5"^^xsd:string) "endoribonuclease I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.5"^^xsd:string) "RNase I activity"^^xsd:string) AnnotationAssertion( "ribonuclease A"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.5"^^xsd:string) "gene S locus-specific glycoproteins"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "RNase H2 activity"^^xsd:string) AnnotationAssertion( "ribonuclease H2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.4"^^xsd:string) "hybrid nuclease activity"^^xsd:string) AnnotationAssertion(rdfs:label "RNA-DNA hybrid ribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) "ribonuclease H activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.4"^^xsd:string) "endoribonuclease H (calf thymus)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.4"^^xsd:string) "hybridase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.4"^^xsd:string) "Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.4"^^xsd:string) "endoribonuclease H"^^xsd:string) AnnotationAssertion( "ribonuclease H1 activity"^^xsd:string) AnnotationAssertion( "ribonuclease H3 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.4"^^xsd:string) "endoribonuclease0 H activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.4"^^xsd:string) "hybrid ribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.4"^^xsd:string) "hybridase (ribonuclease H)"^^xsd:string) AnnotationAssertion( "RNase H3 activity"^^xsd:string) AnnotationAssertion( "calf thymus ribonuclease H activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.4"^^xsd:string) "RNA*DNA hybrid ribonucleotidohydrolase activity"^^xsd:string) AnnotationAssertion( "RNase H activity"^^xsd:string) AnnotationAssertion( "RNase H1 activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ribonuclease III activity"^^xsd:string) AnnotationAssertion( "pre-mRNA 3'-end processing endonuclease"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.3"^^xsd:string) "RNase III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.3"^^xsd:string) "ribonuclease 3 activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11157775"^^xsd:string) Annotation( "PMID:15242644"^^xsd:string) "Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.26.5"^^xsd:string) "Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor."^^xsd:string) AnnotationAssertion( "RNase P"^^xsd:string) AnnotationAssertion(rdfs:label "ribonuclease P activity"^^xsd:string) AnnotationAssertion( "tRNA 5' leader endonuclease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "exonuclease activity"^^xsd:string) AnnotationAssertion( "exonuclease IX activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.1"^^xsd:string) "alkaline phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.1"^^xsd:string) "exonuclease I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.1"^^xsd:string) "5'-PDase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.1"^^xsd:string) "Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.1"^^xsd:string) "5'-exonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.1"^^xsd:string) "5'-NPDase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.1"^^xsd:string) "phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.1"^^xsd:string) "nucleotide pyrophosphatase/phosphodiesterase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.1"^^xsd:string) "5'NPDE activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.1"^^xsd:string) "PDE I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.1"^^xsd:string) "5'-nucleotide phosphodiesterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphodiesterase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.1"^^xsd:string) "5'-phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.1"^^xsd:string) "orthophosphoric diester phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.1"^^xsd:string) "5'-PDE activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.1"^^xsd:string) "oligonucleate 5'-nucleotidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.1"^^xsd:string) "5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "exodeoxyribonuclease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "alkaline DNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "dornavac"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "deoxyribonucleic phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "DNase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "pancreatic deoxyribonuclease"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "endodeoxyribonuclease I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "DNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "Escherichia coli endonuclease I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "pancreatic DNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "DNA depolymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "thymonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "alkaline deoxyribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "DNA endonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "dornava"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "pancreatic dornase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "DNAase activity"^^xsd:string) AnnotationAssertion(rdfs:label "deoxyribonuclease I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "thymonuclease, dornase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "deoxyribonuclease A"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "DNA nuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "deoxyribonuclease (pancreatic)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.1"^^xsd:string) "Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.22.1"^^xsd:string) "pancreatic DNase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.1"^^xsd:string) "Catalysis of the endonucleolytic cleavage of DNA to 3'-phosphodinucleotide and 3'-phosphooligonucleotide end products."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.1"^^xsd:string) "acid DNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.1"^^xsd:string) "deoxyribonucleate 3'-nucleotidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.1"^^xsd:string) "lysosomal DNase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.1"^^xsd:string) "DNase II activity"^^xsd:string) AnnotationAssertion(rdfs:label "deoxyribonuclease II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.1"^^xsd:string) "acid deoxyribonuclease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of an RNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "exoribonuclease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.13.2"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions."^^xsd:string) AnnotationAssertion(rdfs:label "exoribonuclease H activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.13.2"^^xsd:string) "retroviral reverse transcriptase RNaseH"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "5'-3' exoribonuclease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.13.4"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.13.4"^^xsd:string) "2',3'-exoribonuclease activity"^^xsd:string) AnnotationAssertion(rdfs:label "poly(A)-specific ribonuclease activity"^^xsd:string) AnnotationAssertion( "poly(A)-specific RNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.13.4"^^xsd:string) "3'-exoribonuclease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid."^^xsd:string) AnnotationAssertion(rdfs:label "deoxyribonuclease activity"^^xsd:string) AnnotationAssertion( "caspase-activated deoxyribonuclease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA."^^xsd:string) AnnotationAssertion(rdfs:label "ribonuclease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tRNA-specific ribonuclease activity"^^xsd:string) AnnotationAssertion( "tRNA-specific RNase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of phosphodiester bonds in tRNA molecules."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.4.6"^^xsd:string) "nucleoside 5'-diphosphate kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nucleoside diphosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.6"^^xsd:string) "Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.6"^^xsd:string) "nucleoside diphosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.6"^^xsd:string) "nucleoside diphosphate (UDP) kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.6"^^xsd:string) "NDK activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.6"^^xsd:string) "nucleotide phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.6"^^xsd:string) "ATP:nucleoside-diphosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion( "nucleoside-diphosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.6"^^xsd:string) "nucleoside 5'-diphosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.6"^^xsd:string) "UDP kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.6"^^xsd:string) "uridine diphosphate kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.9"^^xsd:string) "Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides."^^xsd:string) AnnotationAssertion(rdfs:label "nucleotide diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.9"^^xsd:string) "nucleotide-sugar pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.9"^^xsd:string) "dinucleotide nucleotidohydrolase activity"^^xsd:string) AnnotationAssertion( "nucleotide pyrophosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.73"^^xsd:string) "octanol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.73"^^xsd:string) Annotation( "RHEA:24623"^^xsd:string) "Catalysis of the reaction: 1-octanol + NAD(+) = 1-octanal + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.73"^^xsd:string) "1-octanol dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "octanol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of any O-glycosyl bond."^^xsd:string) AnnotationAssertion(rdfs:label "hydrolase activity, hydrolyzing O-glycosyl compounds"^^xsd:string) AnnotationAssertion( "O-glucosyl hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.28"^^xsd:string) "Catalysis of the reaction: alpha,alpha-trehalose + H2O = 2 D-glucose."^^xsd:string) AnnotationAssertion(rdfs:label "alpha,alpha-trehalase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.28"^^xsd:string) "alpha,alpha-trehalose glucohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.1"^^xsd:string) "glycogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.1"^^xsd:string) "1,4-alpha-D-glucan glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.1"^^xsd:string) "endoamylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-amylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.1"^^xsd:string) "alpha amylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.1"^^xsd:string) "taka-amylase A"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.1"^^xsd:string) "Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.22"^^xsd:string) "alpha-galactosidase A"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.22"^^xsd:string) "alpha-D-galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.22"^^xsd:string) "alpha-D-galactoside galactohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.22"^^xsd:string) "alpha-galactoside galactohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.22"^^xsd:string) "Catalysis of the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactohydrolase."^^xsd:string) AnnotationAssertion( "melibiase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.20"^^xsd:string) "alpha-D-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.20"^^xsd:string) "acid maltase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.20"^^xsd:string) "glucoinvertase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.20"^^xsd:string) "alpha-glucopyranosidase activity"^^xsd:string) AnnotationAssertion( "alpha-glucosidase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.20"^^xsd:string) "alpha-D-glucoside glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.20"^^xsd:string) "alpha-glucoside hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.20"^^xsd:string) "Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.20"^^xsd:string) "lysosomal alpha-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.20"^^xsd:string) "alpha-1,4-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.20"^^xsd:string) "glucosidoinvertase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.20"^^xsd:string) "glucosidosucrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.20"^^xsd:string) "maltase-glucoamylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.24"^^xsd:string) "Catalysis of the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.24"^^xsd:string) "alpha-D-mannopyranosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.24"^^xsd:string) "alpha-D-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.24"^^xsd:string) "exo-alpha-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.24"^^xsd:string) "1,2-alpha-D-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.24"^^xsd:string) "alpha-D-mannoside mannohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.24"^^xsd:string) "p-nitrophenyl-alpha-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.24"^^xsd:string) "1,2-alpha-mannosidase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.51"^^xsd:string) "Catalysis of the reaction: an alpha-L-fucoside + H2O = an alcohol + L-fucose."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-L-fucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.51"^^xsd:string) "alpha-L-fucoside fucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.51"^^xsd:string) "alpha-fucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.50"^^xsd:string) "alpha-N-acetyl-D-glucosaminide N-acetylglucosaminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.50"^^xsd:string) "N-acetyl-alpha-D-glucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.50"^^xsd:string) "alpha-acetylglucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.50"^^xsd:string) "Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-N-acetylglucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.50"^^xsd:string) "NAG activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.50"^^xsd:string) "N-acetyl-alpha-glucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.50"^^xsd:string) "alpha-D-2-acetamido-2-deoxyglucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-N-acetylhexosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.52"^^xsd:string) "beta-D-N-acetylhexosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.52"^^xsd:string) "Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.52"^^xsd:string) "beta-hexosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.52"^^xsd:string) "N-acetyl-beta-D-hexosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.52"^^xsd:string) "beta-N-acetyl-D-hexosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.52"^^xsd:string) "beta-acetylaminodeoxyhexosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.52"^^xsd:string) "hexosaminidase A"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.52"^^xsd:string) "beta-acetylhexosaminidinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.52"^^xsd:string) "beta-D-hexosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.52"^^xsd:string) "N-acetylhexosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.52"^^xsd:string) "beta-N-acetyl-D-hexosaminide N-acetylhexosaminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.52"^^xsd:string) "N-acetyl-beta-glucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.52"^^xsd:string) "N-acetyl-beta-hexosaminidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "maxinvert L 1000 activity"^^xsd:string) AnnotationAssertion( "alkaline invertase activity"^^xsd:string) AnnotationAssertion( "acid invertase activity"^^xsd:string) AnnotationAssertion( "saccharase activity"^^xsd:string) AnnotationAssertion( "beta-D-fructofuranoside fructohydrolase activity"^^xsd:string) AnnotationAssertion( "glucosucrase activity"^^xsd:string) AnnotationAssertion( "beta-h-fructosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-fructofuranosidase activity"^^xsd:string) AnnotationAssertion( "invertase activity"^^xsd:string) AnnotationAssertion( "fructosylinvertase activity"^^xsd:string) AnnotationAssertion( "beta-fructosidase activity"^^xsd:string) AnnotationAssertion( "invertin activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.26"^^xsd:string) Annotation( "MetaCyc:RXN-9985"^^xsd:string) "Catalysis of the reaction: a fructofuranosylated fructofuranosyl acceptor + H2O = a non fructofuranosylated fructofuranosyl acceptor + a beta-D-fructofuranoside."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.23"^^xsd:string) "Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.23"^^xsd:string) "beta-D-lactosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-galactosidase activity"^^xsd:string) AnnotationAssertion( "lactose hydrolysis"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.23"^^xsd:string) "exo-(1->4)-beta-D-galactanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.23"^^xsd:string) "sumiklat"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.23"^^xsd:string) "lactozym"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.23"^^xsd:string) "maxilact"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.23"^^xsd:string) "oryzatym"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.23"^^xsd:string) "beta-D-galactoside galactohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.23"^^xsd:string) "beta-lactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.23"^^xsd:string) "hydrolact"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.23"^^xsd:string) "S 2107"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.23"^^xsd:string) "beta-D-galactanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.23"^^xsd:string) "trilactase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.31"^^xsd:string) "glucuronidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.31"^^xsd:string) "exo-beta-D-glucuronidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-glucuronidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.31"^^xsd:string) "beta-glucuronide glucuronohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.31"^^xsd:string) "Catalysis of the reaction: a beta-D-glucuronoside + H2O = an alcohol + D-glucuronate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.31"^^xsd:string) "ketodase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.31"^^xsd:string) "beta-D-glucuronoside glucuronosohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.25"^^xsd:string) "Catalysis of the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.25"^^xsd:string) "exo-beta-D-mannanase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.25"^^xsd:string) "beta-D-mannoside mannohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.25"^^xsd:string) "beta-mannoside mannohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.25"^^xsd:string) "mannase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.25"^^xsd:string) "beta-D-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.25"^^xsd:string) "mannanase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.14"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:kah"^^xsd:string) Annotation( "GOC:pde"^^xsd:string) Annotation( "PMID:11468293"^^xsd:string) "Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.14"^^xsd:string) "chitodextrinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.14"^^xsd:string) "1,4-beta-poly-N-acetylglucosaminidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "chitinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.14"^^xsd:string) "poly-beta-glucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.14"^^xsd:string) "beta-1,4-poly-N-acetyl glucosamidinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.14"^^xsd:string) "poly[1,4-(N-acetyl-beta-D-glucosaminide)] glycanohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.130"^^xsd:string) "glucosyl mannosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycoprotein endo-alpha-1,2-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.130"^^xsd:string) "glucosylmannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.130"^^xsd:string) "endomannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.130"^^xsd:string) "glycoprotein glucosylmannohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.130"^^xsd:string) "endo-alpha-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.130"^^xsd:string) "Catalysis of the hydrolysis of the terminal alpha-glucosyl-(1,3)-mannosyl unit from Glc-Man(9)-(GlcNAc)(2) oligosaccharide component of the glycoprotein produced in the Golgi membrane."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.113"^^xsd:string) "Catalysis of the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.113"^^xsd:string) "mannosidase 1A activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.113"^^xsd:string) "mannosidase 1B activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.113"^^xsd:string) "Man9-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.113"^^xsd:string) "1,2-alpha-mannosidase"^^xsd:string) AnnotationAssertion(rdfs:label "mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.113"^^xsd:string) "exo-alpha-1,2-mannanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.113"^^xsd:string) "mannosidase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.113"^^xsd:string) "ManI activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.113"^^xsd:string) "man9-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.113"^^xsd:string) "mannose-9 processing alpha-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.113"^^xsd:string) "1,2-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.113"^^xsd:string) "glycoprotein processing mannosidase I"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.114"^^xsd:string) "exo-1,3-1,6-alpha-mannosidase activity"^^xsd:string) AnnotationAssertion( "mannosyl-oligosaccharide (1->3)-(1->6)-alpha-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.114"^^xsd:string) "ManII activity"^^xsd:string) AnnotationAssertion( "mannosyl-oligosaccharide (1->3,6)-alpha-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.114"^^xsd:string) "mannosidase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.114"^^xsd:string) "Catalysis of the hydrolysis of the terminal (1->3)- and (1->6)-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3)."^^xsd:string) AnnotationAssertion(rdfs:label "mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.114"^^xsd:string) "Golgi alpha-mannosidase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.114"^^xsd:string) "alpha-D-mannosidase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.114"^^xsd:string) "alpha-mannosidase II"^^xsd:string) AnnotationAssertion( "mannosyl-oligosaccharide (1->3/6)-alpha-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.114"^^xsd:string) "1,3-(1,6-)mannosyl-oligosaccharide alpha-D-mannohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.114"^^xsd:string) "GlcNAc transferase I-dependent alpha1,3[alpha1,6]mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.114"^^xsd:string) "alpha-(1,3/6)-mannosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.106"^^xsd:string) "processing A-glucosidase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.106"^^xsd:string) "mannosyl-oligosaccharide glucohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannosyl-oligosaccharide glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.106"^^xsd:string) "Glc3Man9NAc2 oligosaccharide glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.106"^^xsd:string) "Catalysis of the exohydrolysis of the non-reducing terminal glucose residue in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2)."^^xsd:string) AnnotationAssertion( "mannosyl-oligosaccharide glucosidase (processing A-glucosidase I) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.106"^^xsd:string) "trimming glucosidase I"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.10"^^xsd:string) "Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.10"^^xsd:string) "limit dextrinase (erroneous)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rb"^^xsd:string) "alpha-methylglucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.10"^^xsd:string) "alpha-limit dextrinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.10"^^xsd:string) "oligosaccharide alpha-1,6-glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.10"^^xsd:string) "dextrin 6alpha-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.10"^^xsd:string) "exo-oligo-1,6-glucosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oligo-1,6-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.10"^^xsd:string) "isomaltase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.10"^^xsd:string) "sucrase-isomaltase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.10"^^xsd:string) "dextrin 6-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.10"^^xsd:string) "oligosaccharide alpha-1,6-glucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sucrose hydrolysis"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.48"^^xsd:string) "sucrose-alpha-D-glucohydrolase activity"^^xsd:string) AnnotationAssertion( "alpha-D-glucopyranosyl beta-D-fructofuranoside hydrolysis"^^xsd:string) AnnotationAssertion( "sucrose alpha-D-glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.48"^^xsd:string) Annotation( "MetaCyc:RXN-1461"^^xsd:string) "Catalysis of the reaction: sucrose + H2O = alpha-D-glucose + beta-D-fructose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.48"^^xsd:string) "sucrose alpha-glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.48"^^xsd:string) "sucrase-isomaltase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.48"^^xsd:string) "sucrase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sucrose alpha-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.48"^^xsd:string) "intestinal sucrase activity"^^xsd:string) AnnotationAssertion( "beta-D-fructofuranosyl alpha-D-glucopyranoside hydrolysis"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.48"^^xsd:string) "sucrase(invertase)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.119"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "oligosaccharide transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a oligosaccharyl group to an acceptor molecule, typically another carbohydrate or a lipid."^^xsd:string) AnnotationAssertion(rdfs:label "oligosaccharyl transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.141"^^xsd:string) "UDP-N-acetyl-D-glucosamine:N-acetyl-D-glucosaminyl-diphosphodolichol N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.141"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N''-diacetylchitobiosyldiphosphodolichol."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.141"^^xsd:string) "N,N'-diacetylchitobiosylpyrophosphoryldolichol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.141"^^xsd:string) "UDP-GlcNAc:dolichyl-pyrophosphoryl-GlcNAc GlcNAc transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.141"^^xsd:string) "uridine diphosphoacetylglucosamine-dolichylacetylglucosamine pyrophosphate acetylglucosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.142"^^xsd:string) "GDP-mannose-dolichol diphosphochitobiose mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.142"^^xsd:string) "Catalysis of the reaction: GDP-mannose + chitobiosyldiphosphodolichol = GDP + beta-D-mannosylchitobiosyldiphosphodolichol."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.142"^^xsd:string) "GDP-mannose:chitobiosyldiphosphodolichol beta-D-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.142"^^xsd:string) "guanosine diphosphomannose-dolichol diphosphochitobiose mannosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "chitobiosyldiphosphodolichol beta-mannosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.119"^^xsd:string) "dolichyldiphosphooligosaccharide-protein glycosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dolichyl-diphosphooligosaccharide-protein glycotransferase activity"^^xsd:string) AnnotationAssertion( "dolichyl-diphosphooligosaccharide-protein glycosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.119"^^xsd:string) "oligomannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.119"^^xsd:string) "dolichyldiphosphooligosaccharide-protein oligosaccharyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.119"^^xsd:string) "dolichyldiphosphoryloligosaccharide-protein oligosaccharyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.119"^^xsd:string) "dolichylpyrophosphodiacetylchitobiose-protein glycosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.119"^^xsd:string) "dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.119"^^xsd:string) "Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by glycosylamine linkage to protein L-asparagine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.119"^^xsd:string) "asparagine N-glycosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.117"^^xsd:string) "UDP-glucose:dolichol phosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.117"^^xsd:string) "UDP-glucose:dolichyl-phosphate beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.117"^^xsd:string) "UDP-glucose:dolichyl monophosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.117"^^xsd:string) "Catalysis of the reaction: UDP-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.117"^^xsd:string) "uridine diphosphoglucose-dolichol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.117"^^xsd:string) "UDPglucose:dolichyl-phosphate beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.117"^^xsd:string) "UDP-glucose:dolicholphosphoryl glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.117"^^xsd:string) "UDP-glucose:dolichyl phosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.117"^^xsd:string) "polyprenyl phosphate:UDP-D-glucose glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dolichyl-phosphate beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.117"^^xsd:string) "UDP-glucose dolichyl-phosphate glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.83"^^xsd:string) "dolichyl-phospho-mannose synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.83"^^xsd:string) "dolichyl-phosphate mannose synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.83"^^xsd:string) "GDPmannose:dolichyl-phosphate mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.83"^^xsd:string) "GDPMan:DolP mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.83"^^xsd:string) "guanosine diphosphomannose-dolichol phosphate mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.83"^^xsd:string) "dolichyl mannosyl phosphate synthase activity"^^xsd:string) AnnotationAssertion( "DPM synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.83"^^xsd:string) "dolichol-phosphate mannose synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.83"^^xsd:string) "mannosylphosphodolichol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.83"^^xsd:string) "dolichol-phosphate mannosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dolichyl-phosphate beta-D-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.83"^^xsd:string) "GDP-mannose-dolichol phosphate mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.83"^^xsd:string) "GDP-mannose:dolichyl-phosphate beta-D-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.83"^^xsd:string) "dolichyl phosphate mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.83"^^xsd:string) "GDPmannose-dolichylmonophosphate mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.83"^^xsd:string) "Catalysis of the reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate."^^xsd:string) AnnotationAssertion( "dolichol-phosphate-mannose synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.83"^^xsd:string) "dolichol phosphate mannose synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.83"^^xsd:string) "mannosylphosphoryldolichol synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of an alpha-D-glucosyl residue from dolichyl-phosphate D-glucose into a membrane lipid-linked oligosaccharide."^^xsd:string) AnnotationAssertion(rdfs:label "dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.130"^^xsd:string) "dolichol phosphomannose-oligosaccharide-lipid mannosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.130"^^xsd:string) "Catalysis of the transfer of an alpha-D-mannosyl residue from dolichyl-phosphate D-mannose into membrane lipid-linked oligosaccharide."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.130"^^xsd:string) "oligomannosylsynthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.130"^^xsd:string) "dolichyl-phosphate-D-mannose:glycolipid alpha-D-mannosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.3.3"^^xsd:string) "OTC activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.3"^^xsd:string) "ornithine transcarbamylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ornithine carbamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.3"^^xsd:string) "L-ornithine transcarbamylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.3"^^xsd:string) "ornithine carbamyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.3"^^xsd:string) "L-ornithine carbamyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.3"^^xsd:string) "L-ornithine carbamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.3"^^xsd:string) "OTCase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.3"^^xsd:string) "carbamoyl-phosphate:L-ornithine carbamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.3"^^xsd:string) "Catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.3"^^xsd:string) "carbamylphosphate-ornithine transcarbamylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.3"^^xsd:string) "citrulline phosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ornithine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.17"^^xsd:string) Annotation( "RHEA:22967"^^xsd:string) "Catalysis of the reaction: L-ornithine + H(+) = CO(2) + putrescine."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.17"^^xsd:string) "SpeC"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.17"^^xsd:string) "L-ornithine carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.17"^^xsd:string) "L-ornithine carboxy-lyase (putrescine-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "ornithine--keto acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "ornithine:alpha-oxoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "L-ornithine:alpha-ketoglutarate delta-aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "ornithine 5-aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "Catalysis of the reaction: L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "ornithine delta-transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "L-ornithine 5-aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "L-ornithine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "ornithine--oxo acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "GabT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "ornithine ketoacid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "ornithine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "L-ornithine:2-oxo-acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "ornithine--alpha-ketoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "ornithine--ketoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "ornithine aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ornithine-oxo-acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "OAT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "ornithine--oxo-acid transaminase activity"^^xsd:string) AnnotationAssertion( "ornithine-oxo-acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "ornithine--2-oxoacid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.13"^^xsd:string) "ornithine--keto acid aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.10"^^xsd:string) "orotidylic acid phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.10"^^xsd:string) "OPRT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.10"^^xsd:string) "orotidine-5'-phosphate diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.10"^^xsd:string) "OPRTase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.10"^^xsd:string) "orotic acid phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.10"^^xsd:string) "orotidylic phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.10"^^xsd:string) "orotate phosphoribosyl pyrophosphate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.10"^^xsd:string) "orotidine-5'-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.10"^^xsd:string) "orotidylic pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.10"^^xsd:string) "orotidine monophosphate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.10"^^xsd:string) "orotidylate phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "orotate phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.10"^^xsd:string) "orotidylate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.10"^^xsd:string) "Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.10"^^xsd:string) "orotidine phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.10"^^xsd:string) "orotidine 5'-monophosphate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.10"^^xsd:string) "orotidine-5'-phosphate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.10"^^xsd:string) "orotidylic acid pyrophosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "orotate reductase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.14"^^xsd:string) Annotation( "RHEA:13516"^^xsd:string) "Catalysis of the reaction: (S)-dihydroorotate + NAD(+) = H(+) + NADH + orotate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.14"^^xsd:string) "(S)-dihydroorotate:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) "uridine 5'-monophosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) "OMPdcase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) Annotation( "RHEA:11599"^^xsd:string) "Catalysis of the reaction: H(+) + orotidine 5'-phosphate = CO(2) + UMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) "orotate monophosphate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) "UMP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) "orotidine-5'-phosphate carboxy-lyase (UMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) "orotodylate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) "orotic decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) "orotate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) "orotidylic decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) "orotidine-5'-phosphate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) "orotidine monophosphate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) "ODCase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) "OMP decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) "orotidine 5'-phosphate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) "orotidylic acid decarboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "orotidine-5'-phosphate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) "OMP-DC"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) "orotidine phosphate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.23"^^xsd:string) "orotidine-5'-monophosphate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.4.2"^^xsd:string) "2-oxoglutarate:dihydrolipoyllysine-residue succinyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.2"^^xsd:string) "AKGDH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.2"^^xsd:string) "ketoglutaric dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.2"^^xsd:string) "2-ketoglutarate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.2"^^xsd:string) "2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.2"^^xsd:string) "oxoglutarate decarboxylase activity"^^xsd:string) AnnotationAssertion( "oxoglutarate dehydrogenase (lipoamide) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.2"^^xsd:string) "oxoglutarate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oxoglutarate dehydrogenase (succinyl-transferring) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.2"^^xsd:string) "2-oxoglutarate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.2"^^xsd:string) "alpha-ketoglutaric dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.2"^^xsd:string) "OGDC activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.2"^^xsd:string) "alpha-oxoglutarate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.2"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.2"^^xsd:string) "alpha-ketoglutaric acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.2"^^xsd:string) "alpha-ketoglutarate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.2"^^xsd:string) "2-oxoglutarate: lipoate oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.1"^^xsd:string) "(R)-pantoate:beta-alanine ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.1"^^xsd:string) "pantothenate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.1"^^xsd:string) "pantoate-activating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.1"^^xsd:string) "pantoic-activating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.1"^^xsd:string) "D-pantoate:beta-alanine ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "pantoate-beta-alanine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.1"^^xsd:string) "Catalysis of the reaction: ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.22"^^xsd:string) Annotation( "RHEA:12451"^^xsd:string) "Catalysis of the reaction: (R)-pantothenate + H(2)O = (R)-pantoate + beta-alanine."^^xsd:string) AnnotationAssertion(rdfs:label "pantothenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.22"^^xsd:string) "pantothenate amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.22"^^xsd:string) "pantothenate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.22"^^xsd:string) "(R)-pantothenate amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.33"^^xsd:string) "D-pantothenate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.33"^^xsd:string) "Catalysis of the reaction: ATP + pantothenate = ADP + D-4'-phosphopantothenate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.33"^^xsd:string) "ATP:pantothenate 4'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.33"^^xsd:string) "ATP:(R)-pantothenate 4'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.33"^^xsd:string) "pantothenic acid kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pantothenate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.33"^^xsd:string) "pantothenate kinase (phosphorylating) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.3"^^xsd:string) "ATP:pantetheine-4'-phosphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.3"^^xsd:string) "pantetheine phosphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.3"^^xsd:string) "dephospho-CoA diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.3"^^xsd:string) "3'-dephospho-CoA pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.3"^^xsd:string) "PPAT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.3"^^xsd:string) "dephospho-CoA pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pantetheine-phosphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.3"^^xsd:string) "dephospho-coenzyme A pyrophosphorylase activity"^^xsd:string) AnnotationAssertion( "phosphopantetheine adenylyltransferase activity"^^xsd:string) AnnotationAssertion( "ATP:pantetheine-phosphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.3"^^xsd:string) Annotation( "RHEA:19804"^^xsd:string) "Catalysis of the reaction: ATP + pantetheine 4'-phosphate = 3'-dephospho-CoA + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.88"^^xsd:string) "peptide acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.88"^^xsd:string) "acetyl-CoA:peptide nalpha-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.88"^^xsd:string) "acetyl-CoA:peptide alpha-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.88"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide. This reaction is the acetylation of the N-terminal amino acid residue of a peptide or protein."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.88"^^xsd:string) "protein N-terminal acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.88"^^xsd:string) "N(alpha)-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.88"^^xsd:string) "amino-terminal amino acid-acetylating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.88"^^xsd:string) "nalpha-acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "peptide alpha-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.88"^^xsd:string) "NAT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.88"^^xsd:string) "beta-endorphin acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.16"^^xsd:string) "aspartyl/asparaginyl beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "peptide-aspartate beta-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.16"^^xsd:string) "aspartate beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.16"^^xsd:string) "Catalysis of the reaction: peptide L-aspartate + 2-oxoglutarate + O2 = peptide 3-hydroxy-L-aspartate + succinate + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.16"^^xsd:string) "aspartylpeptide beta-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.16"^^xsd:string) "peptide-L-aspartate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.2.5"^^xsd:string) "peptidyl-alpha-hydroxyglycine alpha-amidating lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "peptidylamidoglycolate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.5"^^xsd:string) "PGL"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.5"^^xsd:string) "Catalysis of the reaction: peptidylamidoglycolate = peptidyl amide + glyoxylate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.5"^^xsd:string) "peptidylamidoglycolate peptidylamide-lyase (glyoxylate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.5"^^xsd:string) "PAL"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.5"^^xsd:string) "alpha-hydroxyglycine amidating dealkylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.5"^^xsd:string) "HGAD"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.5"^^xsd:string) "peptidylamidoglycolate peptidylamide-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.11.1.7"^^xsd:string) "japanese radish peroxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.7"^^xsd:string) "donor:hydrogen-peroxide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.7"^^xsd:string) "guaiacol peroxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.7"^^xsd:string) "verdoperoxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.7"^^xsd:string) "pyrocatechol peroxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.7"^^xsd:string) "oxyperoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.7"^^xsd:string) "horseradish peroxidase (HRP)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.7"^^xsd:string) "Catalysis of the reaction: donor + hydrogen peroxide = oxidized donor + 2 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.7"^^xsd:string) "heme peroxidase"^^xsd:string) AnnotationAssertion( "eosinophil peroxidase activity"^^xsd:string) AnnotationAssertion( "peroxidase reaction"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.7"^^xsd:string) "scopoletin peroxidase"^^xsd:string) AnnotationAssertion( "bacterial catalase-peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.7"^^xsd:string) "thiocyanate peroxidase"^^xsd:string) AnnotationAssertion( "myeloperoxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "peroxidase activity"^^xsd:string) AnnotationAssertion( "secretory plant peroxidase activity"^^xsd:string) AnnotationAssertion( "lactoperoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.7"^^xsd:string) "protoheme peroxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.7"^^xsd:string) "extensin peroxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.7"^^xsd:string) "MPO"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "non-selenium glutathione peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.9"^^xsd:string) "GSH peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.9"^^xsd:string) "glutathione:hydrogen-peroxide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.9"^^xsd:string) "selenium-glutathione peroxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutathione peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.9"^^xsd:string) "reduced glutathione peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.9"^^xsd:string) "Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.28"^^xsd:string) "noradrenalin N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.28"^^xsd:string) "norepinephrine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.28"^^xsd:string) "S-adenosyl-L-methionine:phenylethanolamine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.28"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine + N-methylphenylethanolamine."^^xsd:string) AnnotationAssertion(rdfs:label "phenylethanolamine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.28"^^xsd:string) "noradrenaline N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.28"^^xsd:string) "phenethanolamine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.28"^^xsd:string) "norepinephrine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.28"^^xsd:string) "phenethanolamine N-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.4.8"^^xsd:string) "adenosine 3',5'-bisphosphate,sulfite:oxidized-thioredoxin oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.8"^^xsd:string) "PAPS sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.8"^^xsd:string) "PAPS reductase activity"^^xsd:string) AnnotationAssertion( "phosphoadenylyl-sulphate reductase (thioredoxin) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.8"^^xsd:string) "thioredoxin:3'-phospho-adenylylsulfate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.8"^^xsd:string) "PAPS reductase, thioredoxin-dependent activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.8"^^xsd:string) "PAdoPS reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.8"^^xsd:string) "thioredoxin:adenosine 3'-phosphate 5'-phosphosulfate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.8"^^xsd:string) "3'-phosphoadenylylsulfate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.8"^^xsd:string) Annotation( "RHEA:11727"^^xsd:string) "Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.8"^^xsd:string) "adenosine 3',5'-bisphosphate,sulfite:thioredoxin-disulfide oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoadenylyl-sulfate reductase (thioredoxin) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.8"^^xsd:string) "phosphoadenosine-phosphosulfate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "CDP-diacylglycerol synthase activity"^^xsd:string) AnnotationAssertion( "CDP-diglyceride diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.41"^^xsd:string) "CTP:1,2-diacylglycerophosphate-cytidyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.41"^^xsd:string) "DAG synthetase activity"^^xsd:string) AnnotationAssertion( "CDP-diglyceride pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.41"^^xsd:string) "CDP-DG"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.41"^^xsd:string) "phosphatidate cytidyltransferase activity"^^xsd:string) AnnotationAssertion( "CDP-diglyceride synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.41"^^xsd:string) "phosphatidic acid cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.41"^^xsd:string) "CTP:phosphatidate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.41"^^xsd:string) "cytidine diphosphoglyceride pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.41"^^xsd:string) "CDP-diacylglyceride synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.41"^^xsd:string) "CDP-diglyceride synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.41"^^xsd:string) "Catalysis of the reaction: CTP + phosphatidate = diphosphate + CDP-diacylglycerol."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.41"^^xsd:string) "CDP diglyceride pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.41"^^xsd:string) "CTP-diacylglycerol synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.43"^^xsd:string) "lecithin--cholesterol acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.43"^^xsd:string) "LCAT (lecithin-cholesterol acyltransferase)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.43"^^xsd:string) "phosphatidylcholine:sterol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.43"^^xsd:string) "LCAT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.43"^^xsd:string) "phospholipid--cholesterol acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.43"^^xsd:string) "lecithin:cholesterol acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylcholine-sterol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.43"^^xsd:string) "Catalysis of the reaction: phosphatidylcholine + a sterol = a sterol ester + 1-acylglycerophosphocholine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.17"^^xsd:string) "lipid methyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.17"^^xsd:string) "S-adenosyl-L-methionine:phosphatidylethanolamine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.17"^^xsd:string) "phosphatidylethanolamine-S-adenosylmethionine methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylethanolamine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.17"^^xsd:string) "LMTase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.17"^^xsd:string) "phosphatidylethanolamine-N-methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.17"^^xsd:string) "phosphatidylethanolamine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.17"^^xsd:string) Annotation( "RHEA:11167"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H(+) + phosphatidyl-N-methylethanolamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.17"^^xsd:string) "PEMT"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.65"^^xsd:string) "phosphatidyl-L-serine carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.65"^^xsd:string) Annotation( "RHEA:20831"^^xsd:string) "Catalysis of the reaction: H(+) + phosphatidyl-L-serine = CO(2) + phosphatidylethanolamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.65"^^xsd:string) "PS decarboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylserine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.65"^^xsd:string) "phosphatidyl-L-serine carboxy-lyase (phosphatidylethanolamine-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.2.3"^^xsd:string) Annotation( "RHEA:23807"^^xsd:string) "Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.3"^^xsd:string) "N-acetyl-alpha-D-glucosamine 1,6-phosphomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.3"^^xsd:string) "phospho-N-acetylglucosamine mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.3"^^xsd:string) "acetylglucosamine phosphomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.3"^^xsd:string) "acetylaminodeoxyglucose phosphomutase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoacetylglucosamine mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.3"^^xsd:string) "N-acetyl-D-glucosamine 1,6-phosphomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.3"^^xsd:string) "N-acetylglucosamine-phosphate mutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.-"^^xsd:string) "PEPCK activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.-"^^xsd:string) "phosphopyruvate carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.-"^^xsd:string) "PEP carboxykinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.-"^^xsd:string) "Catalysis of the reaction: source of phosphate + oxaloacetate = phosphoenolpyruvate + CO2 + other reaction products."^^xsd:string) AnnotationAssertion(rdfs:label "phosphoenolpyruvate carboxykinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.49"^^xsd:string) Annotation( "RHEA:18620"^^xsd:string) "Catalysis of the reaction: ATP + oxaloacetate = ADP + CO(2) + H(+) + phosphoenolpyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.49"^^xsd:string) "phosphopyruvate carboxylase (ATP)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.49"^^xsd:string) "phosphoenolpyruvate carboxylase (ATP)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.49"^^xsd:string) "phosphopyruvate carboxykinase"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.49"^^xsd:string) "ATP:oxaloacetate carboxy-lyase (transphosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.49"^^xsd:string) "ATP:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.49"^^xsd:string) "phosphoenolpyruvic carboxykinase"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.49"^^xsd:string) "PEPCK (ATP)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.49"^^xsd:string) "phosphopyruvate carboxykinase (adenosine triphosphate)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.49"^^xsd:string) "PEPK"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoenolpyruvate carboxykinase (ATP) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.32"^^xsd:string) "phosphoenolpyruvic carboxylase (GTP)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.32"^^xsd:string) "phosphopyruvate (guanosine triphosphate) carboxykinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.32"^^xsd:string) "GTP:oxaloacetate carboxy-lyase (adding GTP; phosphoenolpyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.32"^^xsd:string) "Catalysis of the reaction: GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "phosphoenolpyruvate carboxykinase (GTP) activity"^^xsd:string) AnnotationAssertion( "phosphoenolpyruvate carboxylase (GTP)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.32"^^xsd:string) "phosphopyruvate carboxylase (GTP)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.32"^^xsd:string) "GTP:oxaloacetate carboxy-lyase (transphosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.32"^^xsd:string) "phosphoenolpyruvic carboxykinase"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.32"^^xsd:string) "phosphoenolpyruvic carboxykinase (GTP)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.2.2"^^xsd:string) "phosphoglucose mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.2"^^xsd:string) "Catalysis of the reaction: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "phosphoglucomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.2"^^xsd:string) "alpha-D-glucose 1,6-phosphomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.2"^^xsd:string) "glucose phosphomutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.2.8"^^xsd:string) "D-mannose 1,6-phosphomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.8"^^xsd:string) "alpha-D-mannose 1,6-phosphomutase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphomannomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.8"^^xsd:string) "phosphomannose mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.8"^^xsd:string) Annotation( "RHEA:11143"^^xsd:string) "Catalysis of the reaction: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.8"^^xsd:string) "mannose phosphomutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.44"^^xsd:string) "6-phosphogluconic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.44"^^xsd:string) "6-phosphogluconic carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.44"^^xsd:string) "6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.44"^^xsd:string) "6-phosphogluconate dehydrogenase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.44"^^xsd:string) "Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.44"^^xsd:string) "6PGD activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.44"^^xsd:string) "phosphogluconic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphogluconate dehydrogenase (decarboxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.44"^^xsd:string) "6-phospho-D-gluconate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "phosphoglyceric acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "alpha-KG reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "Catalysis of the reaction: 3-phosphoglycerate + NAD+ = 3-phosphohydroxypyruvate + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "PGDH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "D-3-phosphoglycerate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "D- and L-HGA"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoglycerate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "3-phosphoglyceric acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "D-3-phosphoglycerate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "alphaKG reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "3PHP reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "glycerate 3-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "SerA"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "SerA 3PG dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "3-phosphoglycerate:NAD+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "3-phosphoglycerate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "alpha-phosphoglycerate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "phosphoglycerate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "3-phospho-D-glycerate:NAD+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.95"^^xsd:string) "glycerate-1,3-phosphate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphoglycerate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.3"^^xsd:string) "ATP-3-phospho-D-glycerate-1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.3"^^xsd:string) "glycerate 3-phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.3"^^xsd:string) "phosphoglyceric acid kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.3"^^xsd:string) Annotation( "RHEA:14804"^^xsd:string) "Catalysis of the reaction: 3-phospho-D-glycerate + ATP = 3-phospho-D-glyceroyl phosphate + ADP + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.3"^^xsd:string) "phosphoglycerokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.3"^^xsd:string) "glycerophosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.3"^^xsd:string) "3-phosphoglyceric kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.3"^^xsd:string) "3-phosphoglycerate phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.3"^^xsd:string) "3-phosphoglycerate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.3"^^xsd:string) "ATP:D-3-phosphoglycerate 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.3"^^xsd:string) "phosphoglyceric kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.3"^^xsd:string) "ATP:3-phospho-D-glycerate 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.3"^^xsd:string) "3-phosphoglyceric acid kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.3"^^xsd:string) "3-phosphoglyceric acid phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.3"^^xsd:string) "PGK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.3"^^xsd:string) "3-PGK"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.2.1"^^xsd:string) "D-phosphoglycerate 2,3-phosphomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.1"^^xsd:string) "monophosphoglycerate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.1"^^xsd:string) "PGAM activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.1"^^xsd:string) "Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.1"^^xsd:string) "PGA mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.1"^^xsd:string) "monophosphoglyceromutase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoglycerate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.1"^^xsd:string) "diphosphoglycomutase"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.1"^^xsd:string) "MPGM"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.1"^^xsd:string) "phosphoglyceromutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.1"^^xsd:string) "bisphosphoglyceromutase"^^xsd:string) AnnotationAssertion( "PGM"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.1"^^xsd:string) "GriP mutase"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.1"^^xsd:string) "phosphoglycerate phosphomutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the hydrolysis of a glycerophospholipid."^^xsd:string) AnnotationAssertion(rdfs:label "phospholipase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycosylphosphatidylinositol phospholipase D activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.50"^^xsd:string) "GPI-PLD activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.50"^^xsd:string) "Catalysis of the reaction: glycoprotein phosphatidylinositol + H2O = phosphatidate + glycoprotein inositol."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.50"^^xsd:string) "glycoprotein-phosphatidylinositol phosphatidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.50"^^xsd:string) "phosphatidylinositol-specific phospholipase D activity"^^xsd:string) AnnotationAssertion( "glycoprotein phospholipase D activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.50"^^xsd:string) "phosphatidylinositol phospholipase D activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.50"^^xsd:string) "phosphatidylinositol-glycan-specific phospholipase D activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.5"^^xsd:string) "lysophosphatidylcholine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.5"^^xsd:string) "phospholipase B activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.5"^^xsd:string) "phosphatidase B"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.5"^^xsd:string) "Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.5"^^xsd:string) "lysophopholipase L2"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.5"^^xsd:string) "lecithinase B activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.5"^^xsd:string) "lysophosphatidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.5"^^xsd:string) "2-lysophosphatidylcholine acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.5"^^xsd:string) "lysolecithinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lysophospholipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.5"^^xsd:string) "lecitholipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.5"^^xsd:string) "lysophospholipase A1"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.4"^^xsd:string) "phosphatidase activity"^^xsd:string) AnnotationAssertion( "cytosolic phospholipase A2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.4"^^xsd:string) "phosphatidolipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.4"^^xsd:string) "phosphatidylcholine 2-acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.4"^^xsd:string) "Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate."^^xsd:string) AnnotationAssertion( "secreted phospholipase A2 activity"^^xsd:string) AnnotationAssertion(rdfs:label "phospholipase A2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.4"^^xsd:string) "lecithinase A activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.4"^^xsd:string) "phospholipase A"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.3"^^xsd:string) "lecithinase C activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.3"^^xsd:string) Annotation( "EC:3.1.4.4"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate."^^xsd:string) AnnotationAssertion(rdfs:label "phospholipase C activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.3"^^xsd:string) "lipophosphodiesterase C"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.3"^^xsd:string) "phosphatidase C"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phospholipase D activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.4"^^xsd:string) "choline phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.4"^^xsd:string) "lecithinase D activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.4"^^xsd:string) "phosphatidylcholine phosphatidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.4"^^xsd:string) "lipophosphodiesterase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.4"^^xsd:string) "Catalysis of the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphomevalonate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.2"^^xsd:string) "ATP:(R)-5-phosphomevalonate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.2"^^xsd:string) "mevalonate phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.2"^^xsd:string) "5-phosphomevalonate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.2"^^xsd:string) "mevalonic acid phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.2"^^xsd:string) "ATP:5-phosphomevalonate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.2"^^xsd:string) "mevalonate-5-phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.2"^^xsd:string) Annotation( "RHEA:16344"^^xsd:string) "Catalysis of the reaction: (R)-5-phosphomevalonate + ATP = (R)-5-diphosphomevalonate + ADP + H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phosphopantothenoylcysteine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.5"^^xsd:string) "(R)-4'-phosphopantothenate:L-cysteine ligase activity"^^xsd:string) AnnotationAssertion( "phosphopantothenate-cysteine ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphopantothenate--cysteine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.5"^^xsd:string) "Catalysis of the reaction: CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + (R)-4'-phosphopantothenoyl-L-cysteine. Cysteine can be replaced by some of its derivatives."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.36"^^xsd:string) "4-phosphopantotheoylcysteine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.36"^^xsd:string) "N-((R)-4'-phosphopantothenoyl)-L-cysteine carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.36"^^xsd:string) Annotation( "RHEA:16796"^^xsd:string) "Catalysis of the reaction: N-[(R)-4-phosphonatopantothenoyl]-L-cysteinate + H(+) = CO(2) + pantetheine 4'-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.36"^^xsd:string) "PPC-decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.36"^^xsd:string) "N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.36"^^xsd:string) "4-phosphopantothenoyl-L-cysteine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.36"^^xsd:string) "N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase (pantotheine-4'-phosphate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "phosphopantothenoylcysteine decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2-phospho-D-glycerate-hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.11"^^xsd:string) "nervous-system specific enolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.11"^^xsd:string) "enolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.11"^^xsd:string) "2-phospho-D-glycerate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.11"^^xsd:string) "2-phosphoglyceric dehydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphopyruvate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.11"^^xsd:string) "2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.11"^^xsd:string) "gamma-enolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.11"^^xsd:string) "14-3-2-protein"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.11"^^xsd:string) "2-phosphoglycerate enolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.11"^^xsd:string) "2-phosphoglycerate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.11"^^xsd:string) "phosphoenolpyruvate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.11"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.19"^^xsd:string) "PRAMP-cyclohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.19"^^xsd:string) "phosphoribosyladenosine monophosphate cyclohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.19"^^xsd:string) Annotation( "RHEA:20052"^^xsd:string) "Catalysis of the reaction: 1-(5-phosphonatoribosyl)-5'-AMP + H(2)O = 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide."^^xsd:string) AnnotationAssertion(rdfs:label "phosphoribosyl-AMP cyclohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.19"^^xsd:string) "1-(5-phospho-D-ribosyl)-AMP 1,6-hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phosphoribosyl-ATP pyrophosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoribosyl-ATP diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.31"^^xsd:string) "phosphoribosyladenosine triphosphate pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.31"^^xsd:string) "1-(5-phosphoribosyl)-ATP diphosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.31"^^xsd:string) Annotation( "RHEA:22831"^^xsd:string) "Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + H(2)O = 1-(5-phosphonatoribosyl)-5'-AMP + diphosphate + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.4.13"^^xsd:string) "5-phospho-D-ribosylamine:glycine ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.13"^^xsd:string) "phosphoribosylglycineamide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.13"^^xsd:string) "glycinamide ribonucleotide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.13"^^xsd:string) "5'-phosphoribosylglycinamide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.13"^^xsd:string) "glycineamide ribonucleotide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.13"^^xsd:string) "GAR synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.13"^^xsd:string) "GAR"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoribosylamine-glycine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.13"^^xsd:string) Annotation( "RHEA:17456"^^xsd:string) "Catalysis of the reaction: 5-phospho-D-ribosylamine + ATP + glycine = N(1)-(5-phospho-D-ribosyl)glycinamide + ADP + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.13"^^xsd:string) "GARS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.13"^^xsd:string) "phosphoribosylglycinamide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.13"^^xsd:string) "2-amino-N-ribosylacetamide 5'-phosphate kinosynthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.21"^^xsd:string) "ADE2"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.21"^^xsd:string) "1-(5-phosphoribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.21"^^xsd:string) "AIR carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.21"^^xsd:string) "5-phosphoribosyl-5-aminoimidazole carboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoribosylaminoimidazole carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.21"^^xsd:string) Annotation( "RHEA:10795"^^xsd:string) "Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.21"^^xsd:string) "5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.21"^^xsd:string) "5-amino-1-ribosylimidazole 5-phosphate carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.21"^^xsd:string) "5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase [5-amino-1-(5-phospho-D-ribosyl)imidazole-forming]"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.21"^^xsd:string) "class II PurE"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.6"^^xsd:string) Annotation( "RHEA:22631"^^xsd:string) "Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.6"^^xsd:string) "phosphoribosylaminoimidazolesuccinocarboxamide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.6"^^xsd:string) "phosphoribosylaminoimidazole-succinocarboxamide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.6"^^xsd:string) "4-[(N-succinylamino)carbonyl]-5-aminoimidazole ribonucleotide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.6"^^xsd:string) "PurC"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.6"^^xsd:string) "SAICAR synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.6"^^xsd:string) "5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate:L-aspartate ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.6"^^xsd:string) "phosphoribosylaminoimidazole-succinocarboxamide synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.6"^^xsd:string) "SAICAR synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.6"^^xsd:string) "SAICARs activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.6"^^xsd:string) "4-((N-succinylamino)carbonyl)-5-aminoimidazole ribonucleotide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.6"^^xsd:string) "4-(N-succinocarboxamide)-5-aminoimidazole synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.6"^^xsd:string) "5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.1.24"^^xsd:string) "PRA isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.24"^^xsd:string) "N-(5'-phosphoribosyl)anthranilate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.24"^^xsd:string) "IGPS:PRAI (indole-3-glycerol-phosphate synthetase/N-5'-phosphoribosylanthranilate isomerase complex)"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.24"^^xsd:string) "N-(5-phospho-beta-D-ribosyl)anthranilate ketol-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.24"^^xsd:string) Annotation( "RHEA:21543"^^xsd:string) "Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.24"^^xsd:string) "PRAI activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoribosylanthranilate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.24"^^xsd:string) "N-(5-phospho-beta-D-ribosyl)anthranilate aldose-ketose-isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.3.1"^^xsd:string) "2-(formamido)-1-N-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.1"^^xsd:string) "AIR synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.1"^^xsd:string) "phosphoribosyl-aminoimidazole synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.1"^^xsd:string) "phosphoribosylaminoimidazole synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoribosylformylglycinamidine cyclo-ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.1"^^xsd:string) "AIR synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.1"^^xsd:string) Annotation( "RHEA:23035"^^xsd:string) "Catalysis of the reaction: 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.1"^^xsd:string) "AIRS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.1"^^xsd:string) "2-(formamido)-N1-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.1"^^xsd:string) "5'-aminoimidazole ribonucleotide synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.5.3"^^xsd:string) "phosphoribosylformylglycinamidine synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoribosylformylglycinamidine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.3"^^xsd:string) "formylglycinamide ribonucloetide amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.3"^^xsd:string) "N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.3"^^xsd:string) "FGARAT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.3"^^xsd:string) "2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.3"^^xsd:string) "formylglycinamide ribotide amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.3"^^xsd:string) "FGAM synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.3"^^xsd:string) "5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.3"^^xsd:string) "phosphoribosylformylglycineamidine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.3"^^xsd:string) "FGAR amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.3"^^xsd:string) Annotation( "RHEA:17132"^^xsd:string) "Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H(2)O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.3"^^xsd:string) "FGAM synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.2.3"^^xsd:string) "Catalysis of the reaction: 10-formyltetrahydrofolate + 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide = tetrahydrofolate + 5'-phosphoribosyl-5-formamido-4-imidazolecarboxamide."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.3"^^xsd:string) "5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.3"^^xsd:string) "5-amino-4-imidazolecarboxamide ribotide transformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.3"^^xsd:string) "10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazole-carboxamide N-formyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.3"^^xsd:string) "aminoimidazolecarboxamide ribonucleotide transformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.3"^^xsd:string) "5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.3"^^xsd:string) "10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.3"^^xsd:string) "AICAR formyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.3"^^xsd:string) "AICAR transformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.3"^^xsd:string) "5-amino-4-imidazolecarboxamide ribonucleotide transformylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoribosylaminoimidazolecarboxamide formyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.2.2"^^xsd:string) "10-formyltetrahydrofolate:5'-phosphoribosylglycinamide N-formyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.2"^^xsd:string) "GAR formyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.2"^^xsd:string) "5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.2"^^xsd:string) "5'-phosphoribosylglycinamide transformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.2"^^xsd:string) "Catalysis of the reaction: 10-formyltetrahydrofolate + N1-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.2"^^xsd:string) "glycinamide ribonucleotide transformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.2"^^xsd:string) "GAR transformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.2"^^xsd:string) "GART activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.2"^^xsd:string) "2-amino-N-ribosylacetamide 5'-phosphate transformylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoribosylglycinamide formyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.2"^^xsd:string) "GAR TFase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.1"^^xsd:string) "amylopectin phosphorylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.1"^^xsd:string) "amylophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.1"^^xsd:string) "polyphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.1"^^xsd:string) "1,4-alpha-glucan phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.1"^^xsd:string) "potato phosphorylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.1"^^xsd:string) "1,4-alpha-D-glucan:phosphate alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.1"^^xsd:string) "starch phosphorylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.1"^^xsd:string) "muscle phosphorylase a and b activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.1"^^xsd:string) "myophosphorylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.1"^^xsd:string) "alpha-glucan phosphorylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.1"^^xsd:string) "granulose phosphorylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.1"^^xsd:string) "glucan phosphorylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.1"^^xsd:string) "Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. The name should be qualified in each instance by adding the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, glycogen phosphorylase."^^xsd:string) AnnotationAssertion(rdfs:label "phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.1"^^xsd:string) "glucosan phosphorylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.1"^^xsd:string) "muscle phosphorylase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.3"^^xsd:string) "Catalysis of the reaction: L(or D)-O-phosphoserine + H2O = L(or D)-serine + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.3"^^xsd:string) "O-phosphoserine phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoserine phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.52"^^xsd:string) "PdxC"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.52"^^xsd:string) "hydroxypyruvic phosphate--glutamic transaminase activity"^^xsd:string) AnnotationAssertion( "phosphoserine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.52"^^xsd:string) "phosphohydroxypyruvic--glutamic transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.52"^^xsd:string) "3-O-phospho-L-serine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.52"^^xsd:string) "PSAT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.52"^^xsd:string) "phosphohydroxypyruvate transaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "O-phospho-L-serine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.52"^^xsd:string) "Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.52"^^xsd:string) "3PHP transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.52"^^xsd:string) "3-phosphoserine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.52"^^xsd:string) "SerC"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.52"^^xsd:string) "phosphoserine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.52"^^xsd:string) "L-phosphoserine aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.143"^^xsd:string) "Catalysis of the hydrolysis of poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose."^^xsd:string) AnnotationAssertion(rdfs:label "poly(ADP-ribose) glycohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.15"^^xsd:string) "pectin depolymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.15"^^xsd:string) "pectin hydrolase activity"^^xsd:string) AnnotationAssertion( "endopolygalacturonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.15"^^xsd:string) "Catalysis of the random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate and other galacturonans."^^xsd:string) AnnotationAssertion( "poly(1,4-alpha-D-galacturonide) glycanohydrolase activity"^^xsd:string) AnnotationAssertion( "poly-alpha-1,4-galacturonide glycanohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "polygalacturonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.15"^^xsd:string) "pectolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.15"^^xsd:string) "pectin polygalacturonase activity"^^xsd:string) AnnotationAssertion( "endo-D-galacturonase activity"^^xsd:string) AnnotationAssertion( "endo-polygalacturonase activity"^^xsd:string) AnnotationAssertion( "endogalacturonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.15"^^xsd:string) "pectinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.33"^^xsd:string) "polynucleotide 5'-triphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.33"^^xsd:string) "polynucleotide 5'-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.33"^^xsd:string) "5'-polynucleotidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "polynucleotide 5'-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.33"^^xsd:string) "Catalysis of the reaction: 5'-phosphopolynucleotide + H2O = polynucleotide + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "ATP:polynucleotidylexotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "terminal riboadenylate transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "polynucleotide adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "poly(A) hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "poly(A) polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "polyadenylic polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "RNA adenylating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "polyadenylate nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "AMP polynucleotidylexotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "NTP polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "polyadenylate polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "ATP-polynucleotide adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "adenosine triphosphate:ribonucleic acid adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "poly-A polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "polyadenylic acid polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "ATP:polynucleotide adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "polyadenylate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "poly(A) synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.19"^^xsd:string) "RNA formation factors, PF1"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.41"^^xsd:string) "UDP-N-acetylgalactosamine-glycoprotein N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.41"^^xsd:string) "UDP-acetylgalactosamine:peptide-N-galactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.41"^^xsd:string) "glycoprotein acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.41"^^xsd:string) "polypeptide-N-acetylgalactosamine transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.41"^^xsd:string) "UDP-acetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.41"^^xsd:string) "UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.41"^^xsd:string) "UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.41"^^xsd:string) "UDP-N-acetylgalactosamine-protein N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.41"^^xsd:string) "UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "polypeptide N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.41"^^xsd:string) "uridine diphosphoacetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.41"^^xsd:string) "UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.41"^^xsd:string) "UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.41"^^xsd:string) Annotation( "ISBN:0879695595"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.41"^^xsd:string) "UDP-N-acetylgalactosamine:kappa-casein polypeptide N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.41"^^xsd:string) "UDP-N-acetylgalactosamine:protein N-acetylgalactosaminyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.41"^^xsd:string) "protein-UDP acetylgalactosaminyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.8"^^xsd:string) "nucleoside diphosphate:polynucleotidyl transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "polyribonucleotide nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.8"^^xsd:string) "polyribonucleotide:phosphate nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.8"^^xsd:string) "Catalysis of the reaction: ATP + RNA(n) = diphosphate + RNA(n+1)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.8"^^xsd:string) "polynucleotide phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.8"^^xsd:string) "polyribonucleotide phosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.24"^^xsd:string) "delta-aminolevulinic acid dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.24"^^xsd:string) "5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing; porphobilinogen-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.24"^^xsd:string) "aminolevulinic dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.24"^^xsd:string) "5-levulinic acid dehydratase activity"^^xsd:string) AnnotationAssertion( "delta-aminolevulinic acid dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.24"^^xsd:string) "delta-aminolevulinic dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.24"^^xsd:string) "delta-aminolevulinate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.24"^^xsd:string) Annotation( "RHEA:24067"^^xsd:string) "Catalysis of the reaction: 2 5-aminolevulinate = 2 H(2)O + H(+) + porphobilinogen."^^xsd:string) AnnotationAssertion(rdfs:label "porphobilinogen synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.24"^^xsd:string) "5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing)"^^xsd:string) AnnotationAssertion( "aminolevulinate dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "procollagen-proline 4-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "protocollagen proline hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "hydroxylase, collagen proline activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "prolylprotocollagen hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "prolylprotocollagen dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "proline hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "prolyl 4-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "protocollagen hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "proline, 2-oxoglutarate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "protocollagen prolyl hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "protocollagen proline dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "prolyl hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "peptidyl proline hydroxylase activity"^^xsd:string) AnnotationAssertion( "procollagen-proline,2-oxoglutarate-4-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "protocollagen proline 4-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "proline protocollagen hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "proline,2-oxoglutarate 4-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) "collagen proline hydroxylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.99.8"^^xsd:string) "L-proline:(acceptor) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.8"^^xsd:string) "Catalysis of the reaction: L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.8"^^xsd:string) "L-proline:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "proline dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.8"^^xsd:string) "L-proline dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.4.1.3"^^xsd:string) "PCCase activity"^^xsd:string) AnnotationAssertion(rdfs:label "propionyl-CoA carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.3"^^xsd:string) "propanoyl-CoA:carbon-dioxide ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.3"^^xsd:string) "Catalysis of the reaction: ATP + propanoyl-CoA + HCO3- = ADP + phosphate + (S)-methylmalonyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.3"^^xsd:string) "propionyl coenzyme A carboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "prenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.58"^^xsd:string) "farnesyl-diphosphate:protein-cysteine farnesyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.58"^^xsd:string) "CAAX farnesyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.58"^^xsd:string) "FTase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.58"^^xsd:string) Annotation( "PMID:8621375"^^xsd:string) "Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "protein farnesyltransferase activity"^^xsd:string) AnnotationAssertion( "protein-cysteine farnesyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:8621375"^^xsd:string) "Catalysis of the covalent addition of a geranylgeranyl (20-carbon isoprenoid) group via thioether linkages to a cysteine residue at or near the C terminus of a protein."^^xsd:string) AnnotationAssertion( "protein-cysteine geranylgeranyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein geranylgeranyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.59"^^xsd:string) "protein geranylgeranyltransferase type I"^^xsd:string) AnnotationAssertion( "GGTase-I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.59"^^xsd:string) "type I protein geranyl-geranyltransferase activity"^^xsd:string) AnnotationAssertion( "GGTaseI activity"^^xsd:string) AnnotationAssertion( "geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.59"^^xsd:string) Annotation( "PMID:8621375"^^xsd:string) "Catalysis of the reaction: geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate. This reaction is the formation of a thioether linkage between the C-1 atom of the geranylgeranyl group and a cysteine residue fourth from the C-terminus of the protein. The protein substrates have the C-terminal sequence CA1A2X, where the terminal residue, X, is preferably leucine and A2 should not be aromatic. Known substrates include most g-subunits of heterotrimeric G proteins and Ras-related GTPases such as members of the Ras and Rac/Rho families."^^xsd:string) AnnotationAssertion( "geranylgeranyltransferase type I activity"^^xsd:string) AnnotationAssertion(rdfs:label "CAAX-protein geranylgeranyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Rab geranylgeranyltransferase activity"^^xsd:string) AnnotationAssertion( "GGTaseII activity"^^xsd:string) AnnotationAssertion( "protein geranylgeranyltransferase type II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.60"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:8621375"^^xsd:string) "Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.60"^^xsd:string) "type II protein geranyl-geranyltransferase activity"^^xsd:string) AnnotationAssertion( "Rab-protein geranylgeranyltransferase activity"^^xsd:string) AnnotationAssertion( "GGTase-II activity"^^xsd:string) AnnotationAssertion( "geranylgeranyl-diphosphate,geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity"^^xsd:string) AnnotationAssertion( "RabGGTase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.51"^^xsd:string) "Catalysis of the reaction: prephenate = phenylpyruvate + H2O + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.51"^^xsd:string) "prephenate hydro-lyase (decarboxylating; phenylpyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.51"^^xsd:string) "prephenate hydro-lyase (decarboxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "prephenate dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.13"^^xsd:string) "prephenate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.13"^^xsd:string) Annotation( "RHEA:21643"^^xsd:string) "Catalysis of the reaction: NADP(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "prephenate dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.13"^^xsd:string) "prephenate:NADP+ oxidoreductase (decarboxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.1"^^xsd:string) "prostaglandin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.1"^^xsd:string) "PG synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.1"^^xsd:string) "prostaglandin synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.1"^^xsd:string) "(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "prostaglandin-endoperoxide synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.1"^^xsd:string) "Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.1"^^xsd:string) "fatty acid cyclooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.1"^^xsd:string) "(PG)H synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.1"^^xsd:string) "prostaglandin endoperoxide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.1"^^xsd:string) "prostaglandin G/H synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.99.2"^^xsd:string) "prostaglandin D2 synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.2"^^xsd:string) "PGD2 synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.2"^^xsd:string) "(5,13)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate D-isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "prostaglandin-D synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.2"^^xsd:string) Annotation( "RHEA:10603"^^xsd:string) "Catalysis of the reaction: prostaglandin H(2) = prostaglandin D(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.2"^^xsd:string) "prostaglandin-R-prostaglandin D isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.2"^^xsd:string) "prostaglandin-H2 D-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.2"^^xsd:string) "PGH-PGD isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.15"^^xsd:string) "Catalysis of the reaction: protein L-arginine + H2O = protein L-citrulline + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.15"^^xsd:string) "protein-L-arginine iminohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-arginine deiminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.15"^^xsd:string) "peptidylarginine deiminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.100"^^xsd:string) "protein C-terminal farnesylcysteine O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.100"^^xsd:string) "farnesyl-protein carboxymethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.100"^^xsd:string) "prenylcysteine carboxylmethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.100"^^xsd:string) "S-farnesylcysteine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.100"^^xsd:string) "farnesyl cysteine C-terminal methyltransferase activity"^^xsd:string) AnnotationAssertion( "protein-S-isoprenylcysteine O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.100"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.100"^^xsd:string) "S-adenosyl-L-methionine:protein-C-terminal-S-farnesyl-L-cysteine O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.100"^^xsd:string) "isoprenylcysteine carboxylmethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.100"^^xsd:string) "farnesylated protein C-terminal O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.100"^^xsd:string) "prenylcysteine carboxyl methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.100"^^xsd:string) "prenylated protein methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.100"^^xsd:string) "protein S-farnesylcysteine C-terminal methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.100"^^xsd:string) "prenylated protein carboxyl methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.100"^^xsd:string) "isoprenylated protein methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.100"^^xsd:string) "prenylcysteine carboxymethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.100"^^xsd:string) "prenylcysteine methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein kinase activity"^^xsd:string) AnnotationAssertion( "protamine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:PROTEIN-KINASE-RXN"^^xsd:string) "Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.13.3"^^xsd:string) "protein histidine kinase (ambiguous)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.3"^^xsd:string) "HK1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.3"^^xsd:string) "protein kinase (histidine)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.3"^^xsd:string) "protein kinase (histidine) (ambiguous)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.3"^^xsd:string) "Sln1p"^^xsd:string) AnnotationAssertion( "protein-histidine kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein histidine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.3"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.3"^^xsd:string) "histidine protein kinase (ambiguous)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.3"^^xsd:string) "histidine protein kinase activity"^^xsd:string) AnnotationAssertion( "histidine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.3"^^xsd:string) "ATP:protein-L-histidine N-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.3"^^xsd:string) "HP165"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.3"^^xsd:string) "EnvZ"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.3"^^xsd:string) "histidine kinase (ambiguous)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "atypical protein kinase C activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "serine-specific protein kinase activity"^^xsd:string) AnnotationAssertion( "galactosyltransferase-associated kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "HIPK2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "glycogen synthase A kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "Raf kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "mitogen-activated S6 kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "non-specific serine/threonine protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "phosphorylase B kinase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "dsk1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "Prp4 protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "cytidine 3',5'-cyclic monophosphate-responsive protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "Raf-1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "p82 kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "casein kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "hydroxyalkyl-protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "Wee-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "protein-cysteine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "T-antigen kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "protein-aspartyl kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "protein kinase A activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "protein phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "ATP-protein transphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "WEE1Hu"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "ribosomal S6 protein kinase activity"^^xsd:string) AnnotationAssertion( "glycogen synthase kinase 3 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "PKC"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "phosphorylase b kinase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "protein serine-threonine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "serine(threonine) protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "glycogen synthase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "PKA"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "M phase-specific cdc2 kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "AP50 kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "A-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "protein kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "serine/threonine protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "protein serine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "MAPK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "STK32"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "calcium/phospholipid-dependent protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "protein-serine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "mitogen-activated protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "protein glutamyl kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "betaIIPKC"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "serine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "protein kinase p58 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "Hpr kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "Wee 1-like kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "ribosomal protein S6 kinase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "ATP:protein phosphotransferase (non-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "epsilon PKC"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "serine protein kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein serine/threonine kinase activity"^^xsd:string) AnnotationAssertion( "atypical PKC activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "twitchin kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.1"^^xsd:string) "threonine-specific protein kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.30"^^xsd:string) "Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.30"^^xsd:string) "ATP:receptor-protein phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.30"^^xsd:string) "receptor protein serine/threonine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.30"^^xsd:string) "receptor type I serine/threonine protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.30"^^xsd:string) "STK13"^^xsd:string) AnnotationAssertion(rdfs:label "transmembrane receptor protein serine/threonine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.30"^^xsd:string) "receptor type II serine/threonine protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.30"^^xsd:string) "TGF-beta kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.30"^^xsd:string) "activin receptor kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.30"^^xsd:string) "receptor serine/threonine protein kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-phosphoinositide-dependent protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "phosphatidylinositol-3-phosphate protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10075713"^^xsd:string) "PDK activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of a phosphatidylinositol-3-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of DNA."^^xsd:string) AnnotationAssertion(rdfs:label "DNA-dependent protein kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "SNF1A/AMP-activated protein kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "AMP-activated protein kinase activity"^^xsd:string) AnnotationAssertion( "5'-AMP-activated protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "AMPK activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of AMP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "calmodulin-dependent kinase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "calcium/calmodulin-dependent protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "CaMKKbeta"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "CAM PKII"^^xsd:string) AnnotationAssertion( "calmodulin regulated protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "CaM kinase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "CaMKII"^^xsd:string) AnnotationAssertion( "multifunctional calcium/calmodulin regulated protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "CaMKIV"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "ATP:caldesmon O-phosphotransferase activity"^^xsd:string) AnnotationAssertion( "Ca2+/CaM-dependent kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "CaM kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "Ca2+/calmodulin-dependent protein kinase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "microtubule-associated protein 2 kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "Ca2+/calmodulin-dependent protein kinase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "calmodulin-dependent protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "calcium/calmodulin-dependent protein kinase type II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "ATP:protein phosphotransferase (Ca2+/calmodulin-dependent) activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:11264466"^^xsd:string) "Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions require the presence of calcium-bound calmodulin."^^xsd:string) AnnotationAssertion( "calcium- and calmodulin-dependent protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "Ca2+/calmodulin-dependent protein kinase activity"^^xsd:string) AnnotationAssertion( "multifunctional calcium- and calmodulin-regulated protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "STK20"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "CaM-regulated serine/threonine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "Ca2+/calmodulin-dependent protein kinase 1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "caldesmon kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "Ca2+/calmodulin-dependent protein kinase IV activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "Ca2+/calmodulin-dependent protein kinase kinase beta activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "CaMKI"^^xsd:string) AnnotationAssertion( "calmodulin-dependent protein kinase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.17"^^xsd:string) "CaMKKalpha"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.20"^^xsd:string) "eukaryotic elongation factor 2 kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "elongation factor-2 kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.20"^^xsd:string) "EF2K"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.20"^^xsd:string) "calmodulin-dependent protein kinase III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.20"^^xsd:string) "elongation factor 2 kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.20"^^xsd:string) "CaM kinase III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.20"^^xsd:string) Annotation( "MetaCyc:2.7.11.20-RXN"^^xsd:string) "Catalysis of the reaction: ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.20"^^xsd:string) "STK19"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.20"^^xsd:string) "eEF2 kinase activity"^^xsd:string) AnnotationAssertion( "eEF-2 kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.20"^^xsd:string) "ATP:elongation factor 2 phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.20"^^xsd:string) "eEF2K"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.20"^^xsd:string) "Ca/CaM-kinase III activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.18"^^xsd:string) "myosin kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.18"^^xsd:string) "calcium/calmodulin-dependent myosin light chain kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.18"^^xsd:string) "ATP:myosin-light-chain O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.18"^^xsd:string) "myosin light-chain kinase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.18"^^xsd:string) "myosin light-chain kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.18"^^xsd:string) "smooth-muscle-myosin-light-chain kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.18"^^xsd:string) "myosin light chain protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.18"^^xsd:string) "MLCK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.18"^^xsd:string) "ATP:myosin-light-chain O-phosphotransferase"^^xsd:string) AnnotationAssertion(rdfs:label "myosin light chain kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.18"^^xsd:string) "MLCkase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.18"^^xsd:string) "STK18"^^xsd:string) AnnotationAssertion( "myosin-light-chain kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.18"^^xsd:string) "myosin light-chain kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.18"^^xsd:string) "myosin light-chain kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.18"^^xsd:string) "Catalysis of the reaction: ATP + myosin-light-chain = ADP + myosin-light-chain phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.19"^^xsd:string) "dephosphophosphorylase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.19"^^xsd:string) "phosphorylase kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.19"^^xsd:string) "PHK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.19"^^xsd:string) "phosphorylase B kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphorylase kinase activity"^^xsd:string) AnnotationAssertion( "phosphorylase kinase, intrinsic catalyst activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.19"^^xsd:string) "ATP:phosphorylase-b phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.19"^^xsd:string) "glycogen phosphorylase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.19"^^xsd:string) "STK17"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.19"^^xsd:string) "Catalysis of the reaction: 4 ATP + 2 phosphorylase b = 4 ADP + phosphorylase a."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of a cyclic nucleotide."^^xsd:string) AnnotationAssertion(rdfs:label "cyclic nucleotide-dependent protein kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.11"^^xsd:string) "AMPK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.11"^^xsd:string) "PKA"^^xsd:string) AnnotationAssertion( "adenosine 3',5'-cyclophosphate-dependent protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.11"^^xsd:string) "protein kinase A activity"^^xsd:string) AnnotationAssertion( "cAMP-dependent protein kinase, intrinsic catalyst activity"^^xsd:string) AnnotationAssertion(rdfs:label "cAMP-dependent protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.11"^^xsd:string) "ATP:protein phosphotransferase (cAMP-dependent) activity"^^xsd:string) AnnotationAssertion( "cyclic AMP-dependent protein kinase activity"^^xsd:string) AnnotationAssertion( "3',5' cAMP-dependent protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.11"^^xsd:string) "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cAMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.11"^^xsd:string) "PKA C"^^xsd:string) AnnotationAssertion( "3',5'-cAMP-dependent protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.11"^^xsd:string) "STK22"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.12"^^xsd:string) "cGMP-dependent protein kinase ibeta activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.12"^^xsd:string) "ATP:protein phosphotransferase (cGMP-dependent) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.12"^^xsd:string) "guanosine 3':5'-cyclic monophosphate-dependent protein kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cGMP-dependent protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cGMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.12"^^xsd:string) "PKG 1alpha"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.12"^^xsd:string) "STK23"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.12"^^xsd:string) "PKG"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.12"^^xsd:string) "PKG 1beta"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.12"^^xsd:string) "3':5'-cyclic GMP-dependent protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.12"^^xsd:string) "PKG II"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "CDK, catalytic subunit activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pr"^^xsd:string) Annotation( "GOC:rn"^^xsd:string) Annotation( "PMID:7877684"^^xsd:string) Annotation( "PMID:9841670"^^xsd:string) "Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.22"^^xsd:string) "cyclin-dependent kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.22"^^xsd:string) "cyclin-A associated kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.22"^^xsd:string) "cdk-activating kinase activity"^^xsd:string) AnnotationAssertion( "cyclin-dependent protein kinase, intrinsic catalyst activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.22"^^xsd:string) "cyclin-dependent kinase 6 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.22"^^xsd:string) "CDK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.22"^^xsd:string) "cdc2 kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.22"^^xsd:string) "cyclin-dependent kinase-2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.22"^^xsd:string) "ATP:cyclin phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.22"^^xsd:string) "cyclin D-cdk6 kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.22"^^xsd:string) "cyclin-dependent kinase-4 activity"^^xsd:string) AnnotationAssertion( "CDK activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.22"^^xsd:string) "Cdk-activating protein kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyclin-dependent protein serine/threonine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.22"^^xsd:string) "neuronal cdc2-like kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.22"^^xsd:string) "cyclin E kinase activity"^^xsd:string) AnnotationAssertion( "cyclin-dependent protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.22"^^xsd:string) "cyclin D-dependent kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.22"^^xsd:string) "D-type cyclin kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "eukaryotic translation initiation factor 2alpha kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "InterPro:IPR015516"^^xsd:string) "Catalysis of the reaction: ATP + [eukaryotic translation initiation factor 2 alpha subunit] = ADP + [eukaryotic translation initiation factor 2 alpha subunit] phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein kinase C activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "nPKCdelta"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "PKCzeta"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "PKCdelta"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "Pkc1p"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "STK24"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "nPKCepsilon"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "protein kinase Cepsilon activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "nPKCeta"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "nPKCtheta"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "cPKCalpha"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "cPKCgamma"^^xsd:string) AnnotationAssertion( "diacylglycerol-activated phospholipid-dependent PKC activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "PKCgamma"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "PKCepsilon"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "PKCalpha"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "cPKCbeta"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "nPKC"^^xsd:string) AnnotationAssertion( "PKC activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "PKCbeta"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "cPKC"^^xsd:string) AnnotationAssertion( "diacylglycerol-activated phospholipid-dependent protein kinase C activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "PKC"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) "ATP:protein phosphotransferase (diacylglycerol-dependent) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "calcium-dependent PKC activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9601053"^^xsd:string) "conventional protein kinase C activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol and calcium."^^xsd:string) AnnotationAssertion(rdfs:label "calcium-dependent protein kinase C activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcium-independent protein kinase C activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9601053"^^xsd:string) "novel protein kinase C activity"^^xsd:string) AnnotationAssertion( "calcium-independent PKC activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol but not calcium."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "receptor signaling protein serine/threonine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.13"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate."^^xsd:string) AnnotationAssertion( "receptor signalling protein serine/threonine kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.16"^^xsd:string) "GPCR kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.16"^^xsd:string) "GPCRK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.16"^^xsd:string) "GRK6"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.16"^^xsd:string) "ATP:G-protein-coupled receptor phosphotransferase activity"^^xsd:string) AnnotationAssertion( "G-protein-coupled receptor phosphorylating protein kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled receptor kinase activity"^^xsd:string) AnnotationAssertion( "G protein coupled receptor phosphorylating protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.16"^^xsd:string) "G-protein-coupled receptor kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.16"^^xsd:string) "G protein-coupled receptor kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "Catalysis of the reaction: ATP + G-protein coupled receptor = ADP + G-protein coupled receptor phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.16"^^xsd:string) "GRK5"^^xsd:string) AnnotationAssertion( "GPCR phosphorylating protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.16"^^xsd:string) "STK16"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.16"^^xsd:string) "GRK4"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NF-kappaB-inducing kinase activity"^^xsd:string) AnnotationAssertion( "NIK"^^xsd:string) AnnotationAssertion(Annotation( "PMID:20685151"^^xsd:string) "Catalysis of the phosphorylation of the alpha or beta subunit of the inhibitor of kappaB kinase complex (IKK)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "JNK"^^xsd:string) AnnotationAssertion( "JNK3alpha1"^^xsd:string) AnnotationAssertion( "SAPK1"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the reaction: JUN + ATP = JUN phosphate + ADP. This reaction is the phosphorylation and activation of members of the JUN family, a gene family that encodes nuclear transcription factors."^^xsd:string) AnnotationAssertion( "c-Jun N-terminal kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "JUN kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "JUN kinase kinase kinase activity"^^xsd:string) AnnotationAssertion( "JNK kinase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Catalysis of the reaction: JNKK + ATP = JNKK phosphate + ADP. This reaction is the phosphorylation and activation of JUN kinase kinases (JNKKs)."^^xsd:string) AnnotationAssertion( "JNKKK"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ERK2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "p38-2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "mitogen-activated protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "MBP kinase II activity"^^xsd:string) AnnotationAssertion( "MAP kinase 1 activity"^^xsd:string) AnnotationAssertion( "MP kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "MBP kinase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "p42mapk"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "ATP:protein phosphotransferase (MAPKK-activated) activity"^^xsd:string) AnnotationAssertion( "Mpk2"^^xsd:string) AnnotationAssertion( "p38"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "ERK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "MAP-2 kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "extracellular signal-regulated kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "myelin basic protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "STK26"^^xsd:string) AnnotationAssertion( "mitogen activated kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ma"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "LeMPK3"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "pp44mapk"^^xsd:string) AnnotationAssertion( "SAPK2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) Annotation( "PMID:20811974"^^xsd:string) "MAPK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "p42 mitogen-activated protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "PMK-3"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "PMK-1"^^xsd:string) AnnotationAssertion( "ERK1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "pp42"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "p44mpk"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "Dp38"^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "PMK-2"^^xsd:string) AnnotationAssertion( "MAP kinase 2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.24"^^xsd:string) "p38delta"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.12.2"^^xsd:string) Annotation( "PMID:20811974"^^xsd:string) "MAPKK"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.2"^^xsd:string) "MAP kinase kinase 4 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.2"^^xsd:string) "MKK7"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.2"^^xsd:string) "MKK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.2"^^xsd:string) "mitogen-activated protein kinase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.2"^^xsd:string) "MEK2"^^xsd:string) AnnotationAssertion( "ERK activator kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.2"^^xsd:string) "MAPKK1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.2"^^xsd:string) "MKK2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.2"^^xsd:string) "STK27"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.2"^^xsd:string) "MEK1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.2"^^xsd:string) "MAP kinase or ERK kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.2"^^xsd:string) "ATP:protein phosphotransferase (MAPKKK-activated) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.2"^^xsd:string) "MAP kinase kinase 7 activity"^^xsd:string) AnnotationAssertion( "MAPKK activity"^^xsd:string) AnnotationAssertion( "MEK activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.2"^^xsd:string) "MKK6"^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.2"^^xsd:string) "MKK4"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.2"^^xsd:string) "MAP2K"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) "MAPK activator activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "MAPK/ERK kinase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.25"^^xsd:string) "REKS"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.25"^^xsd:string) "cRaf"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.25"^^xsd:string) "MEK kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.25"^^xsd:string) "MLTKa"^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase kinase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.25"^^xsd:string) "MEKK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.25"^^xsd:string) "MLK-like mitogen-activated protein triple kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.25"^^xsd:string) "MEKK1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.25"^^xsd:string) "cMos"^^xsd:string) AnnotationAssertion( "MEKK activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.25"^^xsd:string) "MAPKKK activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.25"^^xsd:string) "ATP:protein phosphotransferase (MAPKKKK-activated) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.25"^^xsd:string) "STK28"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.25"^^xsd:string) "MLTKb"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.25"^^xsd:string) "mitogen-activated protein kinase kinase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.25"^^xsd:string) Annotation( "PMID:20811974"^^xsd:string) "MAP3K"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.25"^^xsd:string) "MLTK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.25"^^xsd:string) "MEKK2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.25"^^xsd:string) "Mil/Raf"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9561267"^^xsd:string) "Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.25"^^xsd:string) "MEKK3"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ribosomal protein S6 kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9822608"^^xsd:string) "Catalysis of the reaction: ribosomal protein S6 + ATP = ribosomal protein S6 phosphate + ATP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.12.1"^^xsd:string) "Mps1p"^^xsd:string) AnnotationAssertion( "protein threonine/tyrosine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.1"^^xsd:string) "dDYRK2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.1"^^xsd:string) "Arabidopsis dual specificity kinase 1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.1"^^xsd:string) "ATP:protein phosphotransferase (Ser/Thr- and Tyr-phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.1"^^xsd:string) "ADK1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.1"^^xsd:string) "CLK1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.12.1"^^xsd:string) "dual-specificity kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate."^^xsd:string) AnnotationAssertion( "dual-specificity protein kinase"^^xsd:string) AnnotationAssertion(rdfs:label "protein serine/threonine/tyrosine kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.10"^^xsd:string) "Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate."^^xsd:string) AnnotationAssertion( "JAK"^^xsd:string) AnnotationAssertion( "protein-tyrosine kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein tyrosine kinase activity"^^xsd:string) AnnotationAssertion( "Janus kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.10.1"^^xsd:string) "receptor protein tyrosine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.1"^^xsd:string) "ephrin-B3 receptor tyrosine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.1"^^xsd:string) "Drosophila Eph kinase activity"^^xsd:string) AnnotationAssertion( "neurotrophin TRKC receptor activity"^^xsd:string) AnnotationAssertion( "neurotrophin TRK receptor activity"^^xsd:string) AnnotationAssertion( "sevenless receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.1"^^xsd:string) "ATP:protein-L-tyrosine O-phosphotransferase (receptor-type) activity"^^xsd:string) AnnotationAssertion(rdfs:label "transmembrane receptor protein tyrosine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.1"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate."^^xsd:string) AnnotationAssertion( "neurotrophin TRKA receptor activity"^^xsd:string) AnnotationAssertion( "neurotrophin TRKB receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.1"^^xsd:string) "ATP:protein-tyrosine O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.1"^^xsd:string) "receptor protein-tyrosine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.1"^^xsd:string) "insulin receptor protein-tyrosine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.1"^^xsd:string) "neurite outgrowth regulating kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.1"^^xsd:string) "anaplastic lymphoma kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.1"^^xsd:string) "novel oncogene with kinase-domain activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.10.2"^^xsd:string) "cytoplasmic protein tyrosine kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "non-membrane spanning protein tyrosine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.2"^^xsd:string) "non-specific protein-tyrosine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.2"^^xsd:string) "Catalysis of the reaction: ATP + a non-membrane spanning protein L-tyrosine = ADP + a non-membrane spanning protein L-tyrosine phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.2"^^xsd:string) "p60c-src protein tyrosine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.2"^^xsd:string) "focal adhesion kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.2"^^xsd:string) "Bruton's tyrosine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.2"^^xsd:string) "ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.2"^^xsd:string) "ATP:protein-tyrosine O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.2"^^xsd:string) "janus kinase 1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.2"^^xsd:string) "janus kinase 2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.2"^^xsd:string) "janus kinase 3 activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "receptor signalling protein tyrosine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.10.2"^^xsd:string) "Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "receptor signaling protein tyrosine kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.77"^^xsd:string) "L-aspartyl/L-isoaspartyl protein methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.77"^^xsd:string) "D-aspartyl/L-isoaspartyl methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.77"^^xsd:string) "protein L-isoaspartyl methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.77"^^xsd:string) "protein-beta-aspartate O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.77"^^xsd:string) "protein D-aspartate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.77"^^xsd:string) "L-isoaspartyl protein carboxyl methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.77"^^xsd:string) "protein (D-aspartate) methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.77"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + protein L-beta-aspartate = S-adenosyl-L-homocysteine + protein L-beta-aspartate methyl ester."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.77"^^xsd:string) "protein-L-isoaspartate O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.77"^^xsd:string) "L-isoaspartyl/D-aspartyl protein carboxyl methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.77"^^xsd:string) "protein-L-isoaspartate(D-aspartate) O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.77"^^xsd:string) "protein beta-aspartate O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.77"^^xsd:string) "protein O-methyltransferase (L-isoaspartate)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.77"^^xsd:string) "protein L-isoaspartate methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.77"^^xsd:string) "S-adenosyl-L-methionine:protein-L-isoaspartate O-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.3.13"^^xsd:string) "lysyl oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.13"^^xsd:string) "Catalysis of the reaction: peptidyl-L-lysyl-peptide + H2O + O2 = peptidyl-allysyl-peptide + NH3 + hydrogen peroxide."^^xsd:string) AnnotationAssertion(rdfs:label "protein-lysine 6-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.13"^^xsd:string) "protein-L-lysine:oxygen 6-oxidoreductase (deaminating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "protein phosphatase-2C activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "protein phosphatase-1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "phosphoprotein phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity."^^xsd:string) AnnotationAssertion( "protein phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "protein phosphatase-2A activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoprotein phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "protein phosphatase-2B activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "HMG-CoA reductase phosphatase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "phosphatase IV"^^xsd:string) AnnotationAssertion( "serine/threonine specific protein phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "Aspergillus awamori acid protein phosphatase"^^xsd:string) AnnotationAssertion( "protein phosphatase X"^^xsd:string) AnnotationAssertion(rdfs:label "protein serine/threonine phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "protein D phosphatase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "phosphatase III"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "phosphatase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "phosphatase SP"^^xsd:string) AnnotationAssertion( "protein phosphatase type 4 activity"^^xsd:string) AnnotationAssertion( "protein phosphatase type 2A, intrinsic catalyst activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate."^^xsd:string) AnnotationAssertion( "protein phosphatase type 1, intrinsic catalyst activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "polycation modulated (PCM-) phosphatase"^^xsd:string) AnnotationAssertion( "protein phosphatase type 2A activity"^^xsd:string) AnnotationAssertion( "protein phosphatase type 2B, intrinsic catalyst activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "branched-chain alpha-keto acid dehydrogenase phosphatase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "BCKDH phosphatase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "phosphatase C-II"^^xsd:string) AnnotationAssertion( "protein phosphatase type 2C activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "phosphatase 2B"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "phosphopyruvate dehydrogenase phosphatase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "phosphospectrin phosphatase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase"^^xsd:string) AnnotationAssertion( "protein phosphatase type 1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "phosphatase IB"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "phosphatase 2A"^^xsd:string) AnnotationAssertion( "calcineurin"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "phosphatase H-II"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "casein phosphatase"^^xsd:string) AnnotationAssertion( "protein phosphatase type 2B activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "phosphatase I"^^xsd:string) AnnotationAssertion( "protein phosphatase type 4, intrinsic catalyst activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "calcium-dependent protein serine/threonine phosphatase, intrinsic catalyst activity"^^xsd:string) AnnotationAssertion(rdfs:label "calcium-dependent protein serine/threonine phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of calcium ions."^^xsd:string) AnnotationAssertion( "calcineurin"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of magnesium."^^xsd:string) AnnotationAssertion(rdfs:label "magnesium-dependent protein serine/threonine phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "PTPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "phosphotyrosine phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "protein-tyrosine-phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein tyrosine phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "tyrosylprotein phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "PTP-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "tyrosine O-phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "[phosphotyrosine]protein phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "phosphotyrosine histone phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "PPT-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "protein phosphotyrosine phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "phosphotyrosine protein phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "protein-tyrosine-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "phosphoprotein phosphatase (phosphotyrosine) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "phosphotyrosylprotein phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "non-membrane spanning protein tyrosine phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "Catalysis of the reaction: non-membrane spanning protein tyrosine phosphate + H2O = non-membrane spanning protein tyrosine + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "Catalysis of the reaction: prenylated-protein tyrosine phosphate + H2O = prenylated-protein tyrosine + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "prenylated protein tyrosine phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "receptor signalling protein tyrosine phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "receptor signaling protein tyrosine phosphatase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxygen-dependent protoporphyrinogen oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.4"^^xsd:string) "protoporphyrinogen-IX:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.4"^^xsd:string) Annotation( "RHEA:25579"^^xsd:string) "Catalysis of the reaction: 3 O(2) + protoporphyrinogen IX = 3 H(2)O(2) + protoporphyrin IX."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.70"^^xsd:string) "uracil hydro-lyase (adding D-ribose 5-phosphate)"^^xsd:string) AnnotationAssertion( "pseudouridine monophosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.70"^^xsd:string) "uracil hydro-lyase (adding D-ribose 5-phosphate; pseudouridine-5'-phosphate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.70"^^xsd:string) "uracil hydrolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.70"^^xsd:string) Annotation( "RHEA:18340"^^xsd:string) "Catalysis of the reaction: D-ribose 5-phosphate + uracil = H(2)O + pseudouridine 5'-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.70"^^xsd:string) "psiUMP synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.70"^^xsd:string) "pseudouridylic acid synthetase activity"^^xsd:string) AnnotationAssertion( "pseudouridine-5'-phosphate glycosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pseudouridylate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.70"^^xsd:string) "5-ribosyluracil 5-phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.70"^^xsd:string) "pseudouridylate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.70"^^xsd:string) "pseudouridine monophosphate synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.1"^^xsd:string) "purine deoxynucleoside phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.1"^^xsd:string) "PUNPI"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.1"^^xsd:string) "purine ribonucleoside phosphorylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "purine-nucleoside phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.1"^^xsd:string) "Catalysis of the reaction: purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.1"^^xsd:string) "inosine phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.1"^^xsd:string) "purine nucleoside phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.1"^^xsd:string) "PUNPII"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.1"^^xsd:string) "purine deoxyribonucleoside phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.1"^^xsd:string) "inosine-guanosine phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.1"^^xsd:string) "PNPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.1"^^xsd:string) "purine-nucleoside:phosphate ribosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.3.8"^^xsd:string) "Catalysis of the reaction: pyridoxal + H2O + O2 = 4-pyridoxate + hydrogen peroxide."^^xsd:string) AnnotationAssertion(rdfs:label "pyridoxal oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.8"^^xsd:string) "pyridoxal:oxygen 4-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.3.5"^^xsd:string) "PMP oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.5"^^xsd:string) "pyridoxamine phosphate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.5"^^xsd:string) "pyridoxal 5'-phosphate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyridoxamine-phosphate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.5"^^xsd:string) "pyridoxine (pyridoxamine)phosphate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.5"^^xsd:string) "pyridoxamine-5'-phosphate:oxygen oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.5"^^xsd:string) "pyridoxol-5'-phosphate:oxygen oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.5"^^xsd:string) "pyridoxaminephosphate oxidase (EC 1.4.3.5: deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.5"^^xsd:string) "pyridoxine (pyridoxamine) 5'-phosphate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.5"^^xsd:string) "Catalysis of the reaction: pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH3 + hydrogen peroxide."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.5"^^xsd:string) "pyridoxamine 5'-phosphate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.5"^^xsd:string) "PdxH"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.4.1"^^xsd:string) "PDA synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.4.1"^^xsd:string) "pyrimidodiazepine:glutathione-disulfide oxidoreductase (ring-opening, cyclizing)"^^xsd:string) AnnotationAssertion(rdfs:label "pyrimidodiazepine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.4.1"^^xsd:string) "Catalysis of the reaction: a pyrimidodiazepine + oxidized glutathione = 6-pyruvoyltetrahydropterin + 2 glutathione."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.2"^^xsd:string) "L-proline-NAD(P)+ 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyrroline-5-carboxylate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.2"^^xsd:string) "1-pyrroline-5-carboxylate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.2"^^xsd:string) "NADPH-L-delta1-pyrroline carboxylic acid reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.2"^^xsd:string) "Catalysis of the reaction: L-proline + NADP+ = 1-pyrroline-5-carboxylate + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.2"^^xsd:string) "L-proline oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.2"^^xsd:string) "P5CR activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.2"^^xsd:string) "L-proline:NAD(P)+ 5-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyruvate carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.1"^^xsd:string) "pyruvate:carbon-dioxide ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.1"^^xsd:string) Annotation( "RHEA:20847"^^xsd:string) "Catalysis of the reaction: ATP + bicarbonate + pyruvate = ADP + 2 H(+) + oxaloacetate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.1"^^xsd:string) "pyruvic carboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.1"^^xsd:string) "2-oxo-acid carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.1"^^xsd:string) "alpha-ketoacid carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.1"^^xsd:string) "alpha-carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.1"^^xsd:string) "pyruvic decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.1"^^xsd:string) "2-oxo-acid carboxy-lyase (aldehyde-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "pyruvate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.1"^^xsd:string) "Catalysis of the reaction: a 2-oxo acid = an aldehyde + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.4.1"^^xsd:string) "pyruvic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.1"^^xsd:string) "pyruvic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyruvate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0716020094"^^xsd:string) "Catalysis of the oxidative decarboxylation of pyruvate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.4.1"^^xsd:string) "MtPDC (mitochondrial pyruvate dehydogenase complex) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.1"^^xsd:string) "PDH"^^xsd:string) AnnotationAssertion( "pyruvate dehydrogenase (lipoamide) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.1"^^xsd:string) "pyruvate:dihydrolipoyllysine-residue acetyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.1"^^xsd:string) "pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyruvate dehydrogenase (acetyl-transferring) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.1"^^xsd:string) "pyruvate dehydrogenase complex activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.4.1"^^xsd:string) "Catalysis of the reaction: pyruvate + lipoamide = S-acetyldihydrolipoamide + CO2."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.2"^^xsd:string) "STK1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.2"^^xsd:string) "ATP:pyruvate dehydrogenase (acetyl-transferring) phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.2"^^xsd:string) "PDK3"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.2"^^xsd:string) "PDHK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.2"^^xsd:string) "PDK"^^xsd:string) AnnotationAssertion(rdfs:label "pyruvate dehydrogenase (acetyl-transferring) kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.2"^^xsd:string) "pyruvate dehydrogenase kinase activator protein activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.2"^^xsd:string) "PDK4"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.2"^^xsd:string) "PDK2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.2"^^xsd:string) "PDK1"^^xsd:string) AnnotationAssertion( "pyruvate dehydrogenase (lipoamide) kinase activity"^^xsd:string) AnnotationAssertion( "[pyruvate dehydrogenase (lipoamide)] kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.2"^^xsd:string) "pyruvate dehydrogenase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.2"^^xsd:string) "Catalysis of the reaction: ATP + pyruvate dehydrogenase (acetyl-transferring) = ADP + pyruvate dehydrogenase (acetyl-transferring) phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.2"^^xsd:string) "pyruvate dehydrogenase kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.2"^^xsd:string) "PDH kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.43"^^xsd:string) "pyruvate dehydrogenase (lipoamide)-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.43"^^xsd:string) "phosphopyruvate dehydrogenase phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.43"^^xsd:string) "Catalysis of the reaction: [pyruvate dehydrogenase (lipoamide)] phosphate + H2O = [pyruvate dehydrogenase (lipoamide)] + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.43"^^xsd:string) "pyruvate dehydrogenase phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.43"^^xsd:string) "pyruvate dehydrogenase (lipoamide)-phosphatase activity"^^xsd:string) AnnotationAssertion( "[pyruvate dehydrogenase (lipoamide)] phosphatase, intrinsic catalyst activity"^^xsd:string) AnnotationAssertion(rdfs:label "[pyruvate dehydrogenase (lipoamide)] phosphatase activity"^^xsd:string) AnnotationAssertion( "pyruvate dehydrogenase (lipoamide) phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dihydrolipoyllysine-residue acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.12"^^xsd:string) "transacetylase X activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.12"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + dihydrolipoamide = CoA + S-acetyldihydrolipoamide."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.12"^^xsd:string) "lipoic acid acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.12"^^xsd:string) "lipoate transacetylase activity"^^xsd:string) AnnotationAssertion( "dihydrolipoamide S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.12"^^xsd:string) "lipoic transacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.12"^^xsd:string) "thioltransacetylase A activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.12"^^xsd:string) "lipoate acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.12"^^xsd:string) "dihydrolipoyl acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.12"^^xsd:string) "dihydrolipoate acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.12"^^xsd:string) "acetyl-CoA: enzyme-6-N-(dihydrolipoyl)lysine S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.12"^^xsd:string) "lipoylacetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.12"^^xsd:string) "dihydrolipoic transacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.12"^^xsd:string) "acetyl-CoA: enzyme-N6-(dihydrolipoyl)lysine S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.12"^^xsd:string) "acetyl-CoA:dihydrolipoamide S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.12"^^xsd:string) "enzyme-dihydrolipoyllysine:acetyl-CoA S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.12"^^xsd:string) "lipoic acetyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.40"^^xsd:string) "phosphoenol transphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.40"^^xsd:string) "ATP:pyruvate 2-O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.40"^^xsd:string) "phosphoenolpyruvate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.40"^^xsd:string) "Catalysis of the reaction: ATP + pyruvate = ADP + phosphoenolpyruvate."^^xsd:string) AnnotationAssertion(rdfs:label "pyruvate kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.2.1.3"^^xsd:string) "all-trans-retinal 11-cis-trans-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.3"^^xsd:string) "retinoid isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:24127"^^xsd:string) "Catalysis of the reaction: all-trans-retinal = 11-cis-retinal."^^xsd:string) AnnotationAssertion(rdfs:label "retinal isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.3"^^xsd:string) "retinene isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.105"^^xsd:string) "MDR"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.105"^^xsd:string) "retinol (vitamin A1) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.105"^^xsd:string) "retinol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "retinol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.105"^^xsd:string) "all-trans retinol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.105"^^xsd:string) "retinene reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.105"^^xsd:string) "microsomal retinol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.105"^^xsd:string) "Catalysis of the reaction: retinol + NAD+ = retinal + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) Annotation( "PMID:12036956"^^xsd:string) "retinal reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.9"^^xsd:string) "heavy riboflavin synthase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.9"^^xsd:string) "6,7-dimethyl-8-(1-D-ribityl)lumazine:6,7-dimethyl-8-(1-D-ribityl)lumazine 2,3-butanediyltransferase activity"^^xsd:string) AnnotationAssertion( "vitamin B2 synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "riboflavin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "BRENDA:2.5.1.9"^^xsd:string) "lumazine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.9"^^xsd:string) "light riboflavin synthase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.9"^^xsd:string) Annotation( "RHEA:20775"^^xsd:string) "Catalysis of the reaction: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) = 5-amino-6-(D-ribitylamino)uracil + riboflavin."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.9"^^xsd:string) "riboflavine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.9"^^xsd:string) "riboflavin synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.9"^^xsd:string) "riboflavine synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.15"^^xsd:string) "ribokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.15"^^xsd:string) "ATP:D-ribose 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.15"^^xsd:string) "deoxyribokinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ribokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.15"^^xsd:string) "Catalysis of the reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.15"^^xsd:string) "D-ribokinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "class II ribonucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.4.1"^^xsd:string) "Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin."^^xsd:string) AnnotationAssertion(Annotation( "GOC:pde"^^xsd:string) "ribonucleoside-diphosphate reductase activity"^^xsd:string) AnnotationAssertion( "class I ribonucleotide reductase activity"^^xsd:string) AnnotationAssertion( "adenosylcobalamin-dependent ribonucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.4.1"^^xsd:string) "2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase activity"^^xsd:string) AnnotationAssertion( "class II ribonucleoside-diphosphate reductase activity"^^xsd:string) AnnotationAssertion( "anaerobic iron-sulfur-dependent ribonucleotide reductase activity"^^xsd:string) AnnotationAssertion( "aerobic non-heme iron-dependent ribonucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.4.1"^^xsd:string) "2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.4.1"^^xsd:string) "ribonucleoside diphosphate reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"^^xsd:string) AnnotationAssertion( "purine/pyrimidine nucleoside diphosphate reduction"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.4.1"^^xsd:string) "ribonucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.4.1"^^xsd:string) "ribonucleoside 5'-diphosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.4.1"^^xsd:string) "ribonucleotide diphosphate reductase activity"^^xsd:string) AnnotationAssertion( "RNR"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.4.1"^^xsd:string) "nucleoside diphosphate reductase activity"^^xsd:string) AnnotationAssertion( "class III ribonucleotide reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.6.1"^^xsd:string) "phosphoribosylpyrophosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.1"^^xsd:string) "phosphoribosylpyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.1"^^xsd:string) "ribophosphate pyrophosphokinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ribose phosphate diphosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.1"^^xsd:string) "PPRibP synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.1"^^xsd:string) "ribose-phosphate diphosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.1"^^xsd:string) "PP-ribose P synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.1"^^xsd:string) "PRPP synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.1"^^xsd:string) "5-phosphoribosyl-1-pyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.1"^^xsd:string) "phosphoribosyl-diphosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.1"^^xsd:string) "pyrophosphoribosylphosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.1"^^xsd:string) "phosphoribosyl pyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.1"^^xsd:string) Annotation( "RHEA:15612"^^xsd:string) "Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H(+)."^^xsd:string) AnnotationAssertion( "ribose-phosphate pyrophosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.1"^^xsd:string) "ribose-5-phosphate pyrophosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.1"^^xsd:string) "5-phosphoribose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.1"^^xsd:string) "phosphoribosyl diphosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.1"^^xsd:string) "5-phosphoribosyl-alpha-1-pyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.1"^^xsd:string) "ATP:D-ribose-5-phosphate diphosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.1"^^xsd:string) "D-xylulose-5-phosphate 3-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.1"^^xsd:string) "erythrose-4-phosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.1"^^xsd:string) "phosphoketopentose epimerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ribulose-phosphate 3-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.1"^^xsd:string) "D-ribulose phosphate-3-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.1"^^xsd:string) "D-ribulose-5-phosphate epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.1"^^xsd:string) Annotation( "RHEA:13680"^^xsd:string) "Catalysis of the reaction: D-ribulose 5-phosphate = D-xylulose 5-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.1"^^xsd:string) "pentose-5-phosphate 3-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.1"^^xsd:string) "D-ribulose-5-P 3-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.1"^^xsd:string) "phosphoketopentose 3-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.1"^^xsd:string) "D-ribulose-5-phosphate 3-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.1"^^xsd:string) "D-ribulose 5-phosphate epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.1"^^xsd:string) "xylulose phosphate 3-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.1"^^xsd:string) "erythrose-4-phosphate epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.1"^^xsd:string) "ribulose 5-phosphate 3-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.1"^^xsd:string) "phosphoribulose epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.1.6"^^xsd:string) "D-ribose-5-phosphate ketol-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.6"^^xsd:string) "ribose 5-phosphate epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.6"^^xsd:string) "D-ribose 5-phosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.6"^^xsd:string) Annotation( "RHEA:14660"^^xsd:string) "Catalysis of the reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.6"^^xsd:string) "D-ribose-5-phosphate aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.6"^^xsd:string) "5-phosphoribose isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.6"^^xsd:string) "phosphopentoseisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.6"^^xsd:string) "phosphoriboisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.6"^^xsd:string) "phosphopentosisomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ribose-5-phosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.6"^^xsd:string) "ribose phosphate isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "saccharopine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the cleavage of N6-(L-1,3-dicarboxypropyl)-L-lysine to release an amino acid (lysine or glutamate), with the concomitant reduction of an electron acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.-"^^xsd:string) "lysine-2-oxoglutarate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.-"^^xsd:string) "lysine-ketoglutarate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.7"^^xsd:string) "6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.7"^^xsd:string) "epsilon-N-(L-glutaryl-2)-L-lysine:NAD oxidoreductase (L-lysine forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.7"^^xsd:string) "N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.7"^^xsd:string) Annotation( "RHEA:12443"^^xsd:string) "Catalysis of the reaction: L-saccharopine + H(2)O + NAD(+) = 2-oxoglutarate + L-lysine + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.7"^^xsd:string) "dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, lysine forming)"^^xsd:string) AnnotationAssertion(rdfs:label "saccharopine dehydrogenase (NAD+, L-lysine-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.7"^^xsd:string) "N6-(glutar-2-yl)-L-lysine:NAD oxidoreductase (L-lysine-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.10"^^xsd:string) "N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.10"^^xsd:string) "6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.10"^^xsd:string) "saccharopine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.10"^^xsd:string) Annotation( "RHEA:10023"^^xsd:string) "Catalysis of the reaction: L-saccharopine + H(2)O + NADP(+) = L-allysine + L-glutamate + H(+) + NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.10"^^xsd:string) "aminoadipic semialdehyde-glutamate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.10"^^xsd:string) "aminoadipate semialdehyde-glutamate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.10"^^xsd:string) "epsilon-N-(L-glutaryl-2)-L-lysine:NAD+(P) oxidoreductase (L-2-aminoadipate-semialdehyde forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.10"^^xsd:string) "aminoadipic semialdehyde-glutamic reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.10"^^xsd:string) "saccharopine (nicotinamide adenine dinucleotide phosphate, glutamate-forming) dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.9.3"^^xsd:string) "selenium donor protein activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.3"^^xsd:string) "selenophosphate synthetase activity"^^xsd:string) AnnotationAssertion( "selenophosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.3"^^xsd:string) "ATP:selenide, water phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.3"^^xsd:string) "selenide,water dikinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "selenide, water dikinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.3"^^xsd:string) Annotation( "RHEA:18740"^^xsd:string) "Catalysis of the reaction: ATP + H(2)O + hydrogen selenide = AMP + 3 H(+) + phosphate + selenophosphorate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sepiapterin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.153"^^xsd:string) "7,8-dihydrobiopterin:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.153"^^xsd:string) "Catalysis of the reaction: 7,8-dihydrobiopterin + NADP+ = sepiapterin + NADPH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "serine palmitoyltransferase"^^xsd:string) AnnotationAssertion(rdfs:label "serine C-palmitoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.50"^^xsd:string) "SPT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.50"^^xsd:string) "acyl-CoA:serine C-2 acyltransferase decarboxylating"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.50"^^xsd:string) Annotation( "RHEA:14764"^^xsd:string) "Catalysis of the reaction: L-serine + H(+) + palmitoyl-CoA = 3-dehydrosphinganine + CO(2) + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.50"^^xsd:string) "3-oxosphinganine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.50"^^xsd:string) "palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "serine-pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion( "serine-pyruvate aminotransferase, type 2B"^^xsd:string) AnnotationAssertion( "serine-pyruvate aminotransferase, type 1"^^xsd:string) AnnotationAssertion( "serine-pyruvate aminotransferase, type 2A"^^xsd:string) AnnotationAssertion(rdfs:label "serine-pyruvate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.51"^^xsd:string) "SPT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.51"^^xsd:string) Annotation( "RHEA:22855"^^xsd:string) "Catalysis of the reaction: L-serine + pyruvate = 3-hydroxypyruvate + L-alanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.51"^^xsd:string) "serine--pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.51"^^xsd:string) "hydroxypyruvate:L-alanine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.51"^^xsd:string) "L-serine:pyruvate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.25"^^xsd:string) "dehydroshikimic reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.25"^^xsd:string) "DHS reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.25"^^xsd:string) "Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "shikimate 3-dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.25"^^xsd:string) "shikimate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.25"^^xsd:string) "5-dehydroshikimic reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.25"^^xsd:string) "shikimate:NADP(+) 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.25"^^xsd:string) "5-dehydroshikimate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.25"^^xsd:string) "shikimate:NADP(+) oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.71"^^xsd:string) "shikimate kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.71"^^xsd:string) "shikimate kinase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.71"^^xsd:string) "ATP:shikimate 3-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "shikimate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.71"^^xsd:string) Annotation( "RHEA:13124"^^xsd:string) "Catalysis of the reaction: ATP + shikimate = 3-phosphoshikimate + ADP + 2 H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.16"^^xsd:string) "aminopropyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.16"^^xsd:string) "spermidine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.16"^^xsd:string) "putrescine aminopropyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.16"^^xsd:string) "SpeE"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.16"^^xsd:string) "S-adenosylmethioninamine:putrescine 3-aminopropyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.16"^^xsd:string) "Catalysis of the reaction: S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine."^^xsd:string) AnnotationAssertion(rdfs:label "spermidine synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.12"^^xsd:string) "acid sphingomyelinase activity"^^xsd:string) AnnotationAssertion( "sphingomyelinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.12"^^xsd:string) Annotation( "RHEA:19256"^^xsd:string) "Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.12"^^xsd:string) "neutral sphingomyelinase activity"^^xsd:string) AnnotationAssertion( "neutral sphingomyelin phosphodiesterase"^^xsd:string) AnnotationAssertion(rdfs:label "sphingomyelin phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.12"^^xsd:string) "sphingomyelin cholinephosphohydrolase activity"^^xsd:string) AnnotationAssertion( "acid sphingomyelin phosphodiesterase"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.19.1"^^xsd:string) "stearoyl-CoA, hydrogen-donor:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.19.1"^^xsd:string) "fatty acid desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.19.1"^^xsd:string) "Catalysis of the reaction: stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = oleoyl-CoA + 2 ferricytochrome b5 + H2O."^^xsd:string) AnnotationAssertion( "delta-9 acyl-phospholipid desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.19.1"^^xsd:string) "delta(9)-desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.19.1"^^xsd:string) "acyl-CoA desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.19.1"^^xsd:string) "stearoyl-CoA,ferrocytochrome-b5:oxygen oxidoreductase (9,10-dehydrogenating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.19.1"^^xsd:string) "delta9-desaturase activity"^^xsd:string) AnnotationAssertion(rdfs:label "stearoyl-CoA 9-desaturase activity"^^xsd:string) AnnotationAssertion( "stearoyl-CoA desaturase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.3.1"^^xsd:string) "3-oxosteroid isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.1"^^xsd:string) "delta5-3-keto steroid isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.1"^^xsd:string) "delta(5)-3-keto steroid isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.1"^^xsd:string) "delta5-steroid isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.1"^^xsd:string) "delta5-3-ketosteroid isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "steroid delta-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.1"^^xsd:string) "hydroxysteroid isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.1"^^xsd:string) "delta5(or delta4)-3-keto steroid isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.1"^^xsd:string) "delta(5)-steroid isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.1"^^xsd:string) "3-oxosteroid delta5-delta4-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.1"^^xsd:string) "Catalysis of the reaction: a 3-oxo-delta(5)-steroid = a 3-oxo-delta(4)-steroid."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.1"^^xsd:string) "delta(5)-3-oxosteroid isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.1"^^xsd:string) "delta5-ketosteroid isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.1"^^xsd:string) "delta(5)-3-ketosteroid isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.1"^^xsd:string) "steroid isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.1"^^xsd:string) "delta5-3-oxosteroid isomerase activity"^^xsd:string) AnnotationAssertion( "steroid D-isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.13"^^xsd:string) "Catalysis of the reaction: a steryl ester + H2O = a sterol + a fatty acid."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.13"^^xsd:string) "triterpenol esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.13"^^xsd:string) "cholesterol ester synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.13"^^xsd:string) "cholesterol ester hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sterol esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.13"^^xsd:string) "cholesteryl esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.13"^^xsd:string) "cholesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.13"^^xsd:string) "sterol ester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.13"^^xsd:string) "acylcholesterol lipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.13"^^xsd:string) "cholesteryl ester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.13"^^xsd:string) "cholesteryl ester synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.13"^^xsd:string) "cholesterol esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.13"^^xsd:string) "steryl-ester acylhydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.26"^^xsd:string) "sterol-ester synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.26"^^xsd:string) "sterol-ester synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sterol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.26"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: acyl-CoA + a sterol = CoA + a sterol ester."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.6.2"^^xsd:string) "phenolic steroid sulfatase activity"^^xsd:string) AnnotationAssertion( "steryl-sulphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.2"^^xsd:string) "steroid sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.2"^^xsd:string) "dehydroepiandrosterone sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.2"^^xsd:string) "3-beta-hydroxysteroid sulfate sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.2"^^xsd:string) "steryl-sulfate sulfohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.2"^^xsd:string) "steroid 3-sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.2"^^xsd:string) "dehydroepiandrosterone sulfate sulfatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "steryl-sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.2"^^xsd:string) "sterol sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.2"^^xsd:string) "arylsulfatase C activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.2"^^xsd:string) "Catalysis of the reaction: 3-beta-hydroxyandrost-5-en-17-one 3-sulfate + H2O = 3-beta-hydroxyandrost-5-en-17-one + sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.2"^^xsd:string) "steroid sulfate sulfohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.2"^^xsd:string) "pregnenolone sulfatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.-"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: succinate + CoA + nucleotide triphosphate = nucleotide diphosphate + phosphate + succinyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "succinate-CoA ligase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.5"^^xsd:string) "Catalysis of the reaction: ATP + succinate + CoA = ADP + succinyl-CoA + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.5"^^xsd:string) "succinic thiokinase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.5"^^xsd:string) "succinate:CoA ligase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.5"^^xsd:string) "A-STK (adenin nucleotide-linked succinate thiokinase)"^^xsd:string) AnnotationAssertion(rdfs:label "succinate-CoA ligase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.5"^^xsd:string) "A-SCS"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.5"^^xsd:string) "succinyl coenzyme A synthetase (adenosine diphosphate-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.5"^^xsd:string) "succinyl-CoA synthetase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.5"^^xsd:string) "succinate thiokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.5"^^xsd:string) "succinyl coenzyme A synthetase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.5"^^xsd:string) "succinyl-CoA synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.4"^^xsd:string) "SCS"^^xsd:string) AnnotationAssertion(rdfs:label "succinate-CoA ligase (GDP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.4"^^xsd:string) "Catalysis of the reaction: GTP + succinate + CoA = GDP + succinyl-CoA + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.4"^^xsd:string) "G-STK"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.4"^^xsd:string) "succinyl coenzyme A synthetase (GDP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.4"^^xsd:string) "succinyl coenzyme A synthetase (guanosine diphosphate-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.4"^^xsd:string) "succinyl CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.4"^^xsd:string) "succinic thiokinase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.4"^^xsd:string) "succinyl-CoA synthetase (GDP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.4"^^xsd:string) "succinyl coenzyme A synthetase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.4"^^xsd:string) "succinate-phosphorylating enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.4"^^xsd:string) "P-enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.4"^^xsd:string) "succinate:CoA ligase (GDP-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.24"^^xsd:string) "succinate-semialdehyde:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.24"^^xsd:string) "succinic semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.24"^^xsd:string) "succinyl semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "succinate-semialdehyde dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.24"^^xsd:string) "succinate semialdehyde:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "succinate-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.24"^^xsd:string) "succinate semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.24"^^xsd:string) "Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "succinyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.3"^^xsd:string) "succinyl coenzyme A hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.3"^^xsd:string) "succinyl-CoA acylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.3"^^xsd:string) Annotation( "RHEA:11519"^^xsd:string) "Catalysis of the reaction: H(2)O + succinyl-CoA = CoA + H(+) + succinate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.3"^^xsd:string) "succinyl coenzyme A deacylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sulphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "MetaCyc:SULFATE-ADENYLYLTRANS-RXN"^^xsd:string) Annotation( "MetaCyc:SULFATE-ADENYLYLTRANSFERASE-ADP-RXN"^^xsd:string) "Catalysis of the transfer of an adenylyl group from an adenosine nucleotide (ATP or ADP) to sulfate, forming adenylylsulfate."^^xsd:string) AnnotationAssertion(rdfs:label "sulfate adenylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.5"^^xsd:string) Annotation( "RHEA:16532"^^xsd:string) "Catalysis of the reaction: ADP + H(+) + sulfate = 5'-adenylyl sulfate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.5"^^xsd:string) "sulfate (adenosine diphosphate) adenylyltransferase activity"^^xsd:string) AnnotationAssertion( "ADP:sulfate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.5"^^xsd:string) "adenosine diphosphate sulfurylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfate adenylyltransferase (ADP) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.5"^^xsd:string) "ADP-sulfurylase activity"^^xsd:string) AnnotationAssertion( "sulphate adenylyltransferase (ADP) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.4"^^xsd:string) "adenosinetriphosphate sulfurylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.4"^^xsd:string) "adenosine-5'-triphosphate sulfurylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.4"^^xsd:string) "ATP-sulfurylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.4"^^xsd:string) "sulfate adenylate transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfate adenylyltransferase (ATP) activity"^^xsd:string) AnnotationAssertion( "sulphate adenylyltransferase (ATP) activity"^^xsd:string) AnnotationAssertion( "ATP:sulfate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.4"^^xsd:string) "ATP sulfurylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.4"^^xsd:string) "sulfurylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.4"^^xsd:string) "Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.4"^^xsd:string) "adenylylsulfate pyrophosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.29"^^xsd:string) "Catalysis of the reaction: 3-sulfino-L-alanine = hypotaurine + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.29"^^xsd:string) "cysteic decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.29"^^xsd:string) "CSADCase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.29"^^xsd:string) "CADCase/CSADCase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.29"^^xsd:string) "sulfoalanine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.29"^^xsd:string) "CSAD"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.29"^^xsd:string) "cysteinesulfinate decarboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfinoalanine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.29"^^xsd:string) "cysteinesulfinic acid decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.29"^^xsd:string) "L-cysteinesulfinic acid decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.29"^^xsd:string) "3-sulfino-L-alanine carboxy-lyase activity"^^xsd:string) AnnotationAssertion( "sulphinoalanine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.29"^^xsd:string) "cysteine-sulfinate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.29"^^xsd:string) "3-sulfino-L-alanine carboxy-lyase (hypotaurine-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sulphite reductase (NADPH) activity"^^xsd:string) AnnotationAssertion( "NADPH:sulfite reductase flavoprotein"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.2"^^xsd:string) "hydrogen-sulfide:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.2"^^xsd:string) "Catalysis of the reaction: hydrogen sulfide + 3 NADP+ + 3 H2O = sulfite + 3 NADPH + 3 H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.2"^^xsd:string) "NADPH-dependent sulfite reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.2"^^xsd:string) "H2S-NADP oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.2"^^xsd:string) "NADPH-sulfite reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfite reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.2"^^xsd:string) "sulfite (reduced nicotinamide adenine dinucleotide phosphate) reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "SODF"^^xsd:string) AnnotationAssertion( "copper, zinc superoxide dismutase activity"^^xsd:string) AnnotationAssertion( "iron superoxide dismutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "cuprein"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "superoxide dismutase II"^^xsd:string) AnnotationAssertion( "zinc superoxide oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "Cu,Zn-SOD"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "hemocuprein"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "cytocuprein"^^xsd:string) AnnotationAssertion( "Mn, Fe superoxide dismutase"^^xsd:string) AnnotationAssertion( "manganese superoxide dismutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "superoxide dismutase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "SOD-3"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "SODS"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "Fe-SOD"^^xsd:string) AnnotationAssertion(rdfs:label "superoxide dismutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "SOD-1"^^xsd:string) AnnotationAssertion( "iron superoxide oxidoreductase"^^xsd:string) AnnotationAssertion( "manganese superoxide oxidoreductase"^^xsd:string) AnnotationAssertion( "nickel superoxide dismutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "erythrocuprein"^^xsd:string) AnnotationAssertion( "superoxide:superoxide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "SOD-2"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "ferrisuperoxide dismutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "hepatocuprein"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "Mn-SOD"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "SOD"^^xsd:string) AnnotationAssertion( "nickel superoxide oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "SOD-4"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.1"^^xsd:string) "Cu-Zn superoxide dismutase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "thiamine pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "thiaminpyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "thiamin-pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.-"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: TDP + H2O = TMP + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "thiamine-pyrophosphatase activity"^^xsd:string) AnnotationAssertion( "thiamin pyrophosphatase activity"^^xsd:string) AnnotationAssertion( "TPPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.6.2"^^xsd:string) "thiamin:ATP pyrophosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.2"^^xsd:string) "TPTase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.2"^^xsd:string) "thiamin pyrophosphotransferase activity"^^xsd:string) AnnotationAssertion( "thiamin pyrophosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.2"^^xsd:string) "Catalysis of the reaction: ATP + thiamine = AMP + thiamine diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "thiamin diphosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.2"^^xsd:string) "thiaminokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.2"^^xsd:string) "ATP:thiamine diphosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.2"^^xsd:string) "ATP:thiamin pyrophosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiamine diphosphokinase activity"^^xsd:string) AnnotationAssertion( "thiamine pyrophosphokinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.3"^^xsd:string) "TMP diphosphorylase activity"^^xsd:string) AnnotationAssertion( "thiamine-phosphate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiamine-phosphate diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.3"^^xsd:string) "thiamine-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.3"^^xsd:string) "thiamine phosphate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.3"^^xsd:string) "TMP pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.3"^^xsd:string) "TMP-PPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.3"^^xsd:string) "thiamine monophosphate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.3"^^xsd:string) "2-methyl-4-amino-5-hydroxymethylpyrimidine-diphosphate:4-methyl-5-(2-phosphoethyl)thiazole 2-methyl-4-aminopyrimidine-5-methenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.3"^^xsd:string) Annotation( "RHEA:22331"^^xsd:string) "Catalysis of the reaction: 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5-(2-phosphoethyl)-thiazole + H(+) = diphosphate + thiamine phosphate."^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "thiamin-phosphate diphosphorylase activity"^^xsd:string) AnnotationAssertion( "thiamin-phosphate pyrophosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.96"^^xsd:string) Annotation( "RHEA:19616"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + dimethyl sulfide = S-adenosyl-L-homocysteine + trimethylsulfonium."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.96"^^xsd:string) "thioether methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.96"^^xsd:string) "S-adenosyl-L-methionine:thioether S-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thioether S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.96"^^xsd:string) "S-adenosyl-L-methionine:dimethyl-sulfide S-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.1.9"^^xsd:string) "NADP--thioredoxin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.9"^^xsd:string) "NADPH:oxidized thioredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.9"^^xsd:string) "NADPH2:oxidized thioredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion( "thioredoxin disulfide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.9"^^xsd:string) Annotation( "RHEA:20348"^^xsd:string) "Catalysis of the reaction: NADP(+) + thioredoxin = H(+) + NADPH + thioredoxin disulfide."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.9"^^xsd:string) "thioredoxin:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion( "thioredoxin-disulphide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.9"^^xsd:string) "NADPH--thioredoxin reductase activity"^^xsd:string) AnnotationAssertion( "thioredoxin reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(rdfs:label "thioredoxin-disulfide reductase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "thiosulphate sulphurtransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.1"^^xsd:string) "thiosulfate cyanide transsulfurase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.1"^^xsd:string) "rhodanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.1"^^xsd:string) Annotation( "RHEA:16884"^^xsd:string) "Catalysis of the reaction: hydrogen cyanide + thiosulfate = H(+) + sulfite + thiocyanate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.1"^^xsd:string) "thiosulfate thiotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiosulfate sulfurtransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.1"^^xsd:string) "thiosulfate:cyanide sulfurtransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.1"^^xsd:string) "rhodanese activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.5"^^xsd:string) "L-threonine acetaldehyde-lyase activity"^^xsd:string) AnnotationAssertion( "L-threonine aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.5"^^xsd:string) "Catalysis of the reaction: L-threonine = glycine + acetaldehyde."^^xsd:string) AnnotationAssertion(rdfs:label "threonine aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.5"^^xsd:string) "L-threonine acetaldehyde-lyase (glycine-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "threonine ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.19"^^xsd:string) "L-threonine hydro-lyase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.19"^^xsd:string) "threonine dehydrase activity"^^xsd:string) AnnotationAssertion( "threonine dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.19"^^xsd:string) "serine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.19"^^xsd:string) "threonine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.19"^^xsd:string) "L-threonine dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.19"^^xsd:string) "Catalysis of the reaction: L-threonine = 2-oxobutanoate + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.19"^^xsd:string) "L-serine dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.19"^^xsd:string) "L-threonine ammonia-lyase (2-oxobutanoate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.19"^^xsd:string) "L-threonine deaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-threonine ammonia-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "threonine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.1"^^xsd:string) "Catalysis of the reaction: O-phospho-L-homoserine + H2O = L-threonine + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.1"^^xsd:string) "threonine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.1"^^xsd:string) "O-phospho-L-homoserine phospho-lyase (adding water; L-threonine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.1"^^xsd:string) "O-phospho-L-homoserine phospho-lyase (adding water)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cytochrome P450 CYP5"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.5"^^xsd:string) "thromboxane synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.5"^^xsd:string) "thromboxane synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.5"^^xsd:string) Annotation( "RHEA:17140"^^xsd:string) "Catalysis of the reaction: prostaglandin H(2) = thromboxane A(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.5"^^xsd:string) "(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate thromboxane-A2-isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thromboxane-A synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.5"^^xsd:string) "(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.21"^^xsd:string) "thymidine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.21"^^xsd:string) "ATP:thymidine 5'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.21"^^xsd:string) "2'-deoxythymidine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.21"^^xsd:string) "deoxythymidine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.21"^^xsd:string) "Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "thymidine kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.4.9"^^xsd:string) "thymidylic acid kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.9"^^xsd:string) "ATP:dTMP phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.9"^^xsd:string) "thymidine monophosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.9"^^xsd:string) "thymidylic kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thymidylate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.9"^^xsd:string) "thymidylate monophosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.9"^^xsd:string) "deoxythymidine 5'-monophosphate kinase activity"^^xsd:string) AnnotationAssertion( "dTMP kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.9"^^xsd:string) "thymidine 5'-monophosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.9"^^xsd:string) "Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.9"^^xsd:string) "TMPK activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.45"^^xsd:string) "methylenetetrahydrofolate:dUMP C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.45"^^xsd:string) "TMP synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.45"^^xsd:string) "thymidylate synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thymidylate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.45"^^xsd:string) Annotation( "RHEA:12107"^^xsd:string) "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.45"^^xsd:string) "dTMP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.45"^^xsd:string) "5,10-methylenetetrahydrofolate:dUMP C-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.97.1.10"^^xsd:string) "type II iodothyronine deiodinase activity"^^xsd:string) AnnotationAssertion( "thyroxine 5' deiodinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thyroxine 5'-deiodinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.10"^^xsd:string) "Catalysis of the reaction: 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + donor-H2."^^xsd:string) AnnotationAssertion(Annotation( "PMID:20403357"^^xsd:string) "outer ring-deiodinating pathway"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.10"^^xsd:string) "type I iodothyronine deiodinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.10"^^xsd:string) "iodothyronine outer ring monodeiodinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.10"^^xsd:string) "acceptor:3,5,3'-triiodo-L-thyronine oxidoreductase (iodinating)"^^xsd:string) AnnotationAssertion( "thyroxine deiodinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.10"^^xsd:string) "diiodothyronine 5'-deiodinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.10"^^xsd:string) "iodothyronine 5'-deiodinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.10"^^xsd:string) "L-thyroxine iodohydrolase (reducing) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.2.1.2"^^xsd:string) "transaldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.2"^^xsd:string) "glycerone transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.2"^^xsd:string) "dihydroxyacetonetransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.2"^^xsd:string) "Catalysis of the reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.2"^^xsd:string) "dihydroxyacetone transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.2.1.1"^^xsd:string) "sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.1"^^xsd:string) Annotation( "GOC:fmc"^^xsd:string) "Catalysis of the reversible transfer of a 2-carbon ketol group (CH2OH-CO-) from a ketose phosphate donor to an aldose phosphate acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "transketolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.1"^^xsd:string) "glycolaldehydetransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.1"^^xsd:string) "glycoaldehyde transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:fmc"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "fructose 6-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bm"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element."^^xsd:string) AnnotationAssertion(rdfs:label "transposase activity"^^xsd:string) AnnotationAssertion( "P-element encoded transposase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.12"^^xsd:string) "trehalose 6-phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.12"^^xsd:string) "Catalysis of the reaction: trehalose 6-phosphate + H2O = trehalose + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.12"^^xsd:string) "trehalose-6-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trehalose-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.12"^^xsd:string) "trehalose 6-phosphatase activity"^^xsd:string) AnnotationAssertion( "trehalose phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "lipazin"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "butyrinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "tributyrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "amano B"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "amano P"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "hepatic monoacylglycerol acyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "glycerol-ester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "tributyrinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "amano CE"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "triacylglycerol ester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "salt-resistant post-heparin lipase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "PPL"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "triacylglycerol acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "heparin releasable hepatic lipase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "hepatic lipase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "amno N-AP"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "capalase L"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "triglyceridase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "triglyceride hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "GA 56"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "steapsin"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "tributyrin esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "tween hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "post-heparin plasma protamine-resistant lipase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "tween-hydrolyzing esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "glycerol ester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "amano CES"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "meito MY 30"^^xsd:string) AnnotationAssertion(rdfs:label "triglyceride lipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "takedo 1969-4-9"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "triacylglycerol lipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "GEH"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "amano AP"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "tweenesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "triolein hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "tweenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "meito sangyo OF lipase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "triacetinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "liver lipase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.3"^^xsd:string) "cacordase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.1.1"^^xsd:string) "triose phosphate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.1"^^xsd:string) "D-glyceraldehyde-3-phosphate ketol-isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "triose-phosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.1"^^xsd:string) "triosephosphate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.1"^^xsd:string) "triose phosphoisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.1"^^xsd:string) Annotation( "RHEA:18588"^^xsd:string) "Catalysis of the reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.1"^^xsd:string) "D-glyceraldehyde-3-phosphate aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.1"^^xsd:string) "phosphotriose isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.1"^^xsd:string) "triosephosphate isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.61"^^xsd:string) "S-adenosyl-L-methionine:tRNA (5-methylaminomethyl-2-thio-uridylate)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.61"^^xsd:string) Annotation( "GOC:imk"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing 5-aminomethyl-2-thiouridine = S-adenosyl-L-homocysteine + tRNA containing 5-methylaminomethyl-2-thiouridylate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.61"^^xsd:string) "transfer ribonucleate 5-methylaminomethyl-2-thiouridylate 5-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.61"^^xsd:string) "tRNA 5-methylaminomethyl-2-thiouridylate 5'-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.32"^^xsd:string) "N2,N2-dimethylguanine tRNA methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.32"^^xsd:string) "S-adenosyl-L-methionine:tRNA (guanine-2-N-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.32"^^xsd:string) "guanine-N2-methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.32"^^xsd:string) "tRNA(m(2,2)G26)dimethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.32"^^xsd:string) "tRNA 2,2-dimethylguanosine-26 methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.32"^^xsd:string) "S-adenosyl-L-methionine:tRNA (guanine-N2-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA (guanine-N2-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.32"^^xsd:string) "tRNA(guanine-26,N(2)-N(2)) methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.32"^^xsd:string) "N(2),N(2)-dimethylguanine tRNA methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.32"^^xsd:string) "transfer ribonucleate guanine N2-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.32"^^xsd:string) "tRNA(guanine-26,N2-N2) methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.32"^^xsd:string) "transfer ribonucleate guanine 2-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.32"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing guanine = S-adenosyl-L-homocysteine + tRNA containing N2-methylguanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.32"^^xsd:string) "transfer RNA guanine 2-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "ATP (CTP):tRNA nucleotidyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "CTP(ATP):tRNA nucleotidyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "transfer ribonucleic-terminal trinucleotide nucleotidyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "transfer ribonucleate adenylyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "ATP(CTP)-tRNA nucleotidyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "transfer ribonucleic adenylyl (cytidylyl) transferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "tRNA-nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "transfer ribonucleate adenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "transfer ribonucleic acid nucleotidyl transferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "tRNA CCA-pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "transfer RNA adenylyltransferase"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA adenylyltransferase activity"^^xsd:string) AnnotationAssertion( "ATP:tRNA adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "transfer ribonucleate cytidylyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "-C-C-A pyrophosphorylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "ribonucleic cytidylic cytidylic adenylic pyrophosphorylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "ribonucleic cytidylyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "transfer ribonucleate nucleotidyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "Catalysis of the reaction: ATP + tRNA(n) = diphosphate + tRNA(n+1)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "transfer-RNA nucleotidyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "CCA-adding enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "tRNA CCA-diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.25"^^xsd:string) "tRNA adenylyl(cytidylyl)transferase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "aminoacyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion( "aminoacyl-tRNA synthetase auxiliary protein activity"^^xsd:string) AnnotationAssertion(rdfs:label "aminoacyl-tRNA ligase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.7"^^xsd:string) "alanyl-transfer ribonucleic acid synthetase activity"^^xsd:string) AnnotationAssertion( "alanyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alanine-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.7"^^xsd:string) "alanine translase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.7"^^xsd:string) "L-alanine:tRNAAla ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.7"^^xsd:string) "alanyl-transfer RNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.7"^^xsd:string) "alanine tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.7"^^xsd:string) "Ala-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.7"^^xsd:string) "alanine-transfer RNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.7"^^xsd:string) "alanyl-transfer ribonucleate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.7"^^xsd:string) "Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.7"^^xsd:string) "alanine transfer RNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.7"^^xsd:string) "alanyl-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.7"^^xsd:string) "AlaRS"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.19"^^xsd:string) "arginyl transfer ribonucleic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.19"^^xsd:string) "arginine translase activity"^^xsd:string) AnnotationAssertion( "arginyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.19"^^xsd:string) "arginyl-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.19"^^xsd:string) "L-arginine:tRNAArg ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.19"^^xsd:string) "Catalysis of the reaction: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)."^^xsd:string) AnnotationAssertion(rdfs:label "arginine-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.19"^^xsd:string) "arginine-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.19"^^xsd:string) "arginyl-transfer RNA synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aspartate-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.12"^^xsd:string) "aspartyl-transfer RNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.12"^^xsd:string) "aspartyl ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion( "aspartyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.12"^^xsd:string) "aspartyl ribonucleic synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.12"^^xsd:string) "aspartyl-transfer ribonucleic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.12"^^xsd:string) "Catalysis of the reaction: ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.12"^^xsd:string) "L-aspartate:tRNAAsp ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.12"^^xsd:string) "aspartic acid translase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.22"^^xsd:string) "asparaginyl transfer ribonucleic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.22"^^xsd:string) "asparaginyl transfer RNA synthetase activity"^^xsd:string) AnnotationAssertion( "asparaginyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "asparagine-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.22"^^xsd:string) "L-asparagine:tRNAAsn ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.22"^^xsd:string) Annotation( "RHEA:11183"^^xsd:string) "Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.22"^^xsd:string) "asparaginyl-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.22"^^xsd:string) "asparagine translase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.22"^^xsd:string) "asparagyl-transfer RNA synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.16"^^xsd:string) "cysteinyl-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.16"^^xsd:string) "L-cysteine:tRNACys ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "cysteine-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.16"^^xsd:string) "Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.16"^^xsd:string) "cysteine translase activity"^^xsd:string) AnnotationAssertion( "cysteinyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.16"^^xsd:string) "cysteinyl-transferRNA synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.17"^^xsd:string) "glutamate-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.17"^^xsd:string) "glutamyl-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.17"^^xsd:string) "Catalysis of the reaction: ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.17"^^xsd:string) "glutamyl-transfer RNA synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamate-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.17"^^xsd:string) "glutamic acid translase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.17"^^xsd:string) "glutamyl-transfer ribonucleic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.17"^^xsd:string) "L-glutamate:tRNAGlu ligase (AMP-forming) activity"^^xsd:string) AnnotationAssertion( "glutamyl-tRNA synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.18"^^xsd:string) "GlnRS"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.18"^^xsd:string) "L-glutamine:tRNAGln ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.18"^^xsd:string) "glutaminyl ribonucleic acid"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.18"^^xsd:string) "glutaminyl-transfer RNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.18"^^xsd:string) "Catalysis of the reaction: ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.18"^^xsd:string) "glutamine-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamine-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.18"^^xsd:string) "glutaminyl-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion( "glutaminyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.18"^^xsd:string) "glutamine translase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.14"^^xsd:string) "glycyl-transfer ribonucleic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.14"^^xsd:string) "glycyl-transfer RNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.14"^^xsd:string) "glycyl-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.14"^^xsd:string) "Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)."^^xsd:string) AnnotationAssertion( "glycyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.14"^^xsd:string) "glycyl translase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.14"^^xsd:string) "glycine:tRNAGly ligase (AMP-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycine-tRNA ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "histidyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.21"^^xsd:string) "histidyl-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.21"^^xsd:string) "histidine translase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.21"^^xsd:string) "Catalysis of the reaction: ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His)."^^xsd:string) AnnotationAssertion(rdfs:label "histidine-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.21"^^xsd:string) "L-histidine:tRNAHis ligase (AMP-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.5"^^xsd:string) Annotation( "RHEA:11063"^^xsd:string) "Catalysis of the reaction: L-isoleucine + ATP + tRNA(Ile) = L-isoleucyl-tRNA(Ile) + AMP + diphosphate + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.5"^^xsd:string) "isoleucyl-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.5"^^xsd:string) "isoleucyl-transfer RNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.5"^^xsd:string) "isoleucine-transfer RNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.5"^^xsd:string) "L-isoleucine:tRNAIle ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "isoleucine-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.5"^^xsd:string) "isoleucine translase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.5"^^xsd:string) "isoleucine-tRNA synthetase activity"^^xsd:string) AnnotationAssertion( "isoleucyl-tRNA synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.4"^^xsd:string) "leucyl-transfer ribonucleic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.4"^^xsd:string) "leucine translase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.4"^^xsd:string) "leucine-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.4"^^xsd:string) "L-leucine:tRNALeu ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "leucine-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.4"^^xsd:string) Annotation( "RHEA:11691"^^xsd:string) "Catalysis of the reaction: L-leucine + ATP + tRNA(Leu) = AMP + diphosphate + 2 H(+) + Leu-tRNA(Leu)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.4"^^xsd:string) "leucyl-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion( "leucyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.4"^^xsd:string) "leucyl-transfer RNA synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.6"^^xsd:string) "lysyl-transfer RNA synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lysine-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.6"^^xsd:string) "lysyl-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.6"^^xsd:string) "L-lysine:tRNALys ligase (AMP-forming)"^^xsd:string) AnnotationAssertion( "lysyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.6"^^xsd:string) "lysine translase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.6"^^xsd:string) "Catalysis of the reaction: ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.6"^^xsd:string) "lysine-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.6"^^xsd:string) "L-lysine-transfer RNA ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.10"^^xsd:string) "methionyl-transfer RNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.10"^^xsd:string) "Catalysis of the reaction: ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)."^^xsd:string) AnnotationAssertion(rdfs:label "methionine-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.10"^^xsd:string) "methionyl-transfer ribonucleic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.10"^^xsd:string) "methionine translase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.10"^^xsd:string) "MetRS activity"^^xsd:string) AnnotationAssertion( "methionyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.10"^^xsd:string) "methionyl-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.10"^^xsd:string) "L-methionine:tRNAMet ligase (AMP-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.20"^^xsd:string) "phenylalanyl-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.20"^^xsd:string) "Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.20"^^xsd:string) "L-phenylalanine:tRNAPhe ligase (AMP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.20"^^xsd:string) "phenylalanine-tRNA synthetase activity"^^xsd:string) AnnotationAssertion( "phenylalanyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.20"^^xsd:string) "phenylalanyl-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.20"^^xsd:string) "L-phenylalanyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.20"^^xsd:string) "phenylalanyl-transfer RNA ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phenylalanine-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.20"^^xsd:string) "phenylalanyl-transfer RNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.20"^^xsd:string) "phenylalanine translase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.15"^^xsd:string) "Catalysis of the reaction: ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.15"^^xsd:string) "proline translase activity"^^xsd:string) AnnotationAssertion( "prolyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.15"^^xsd:string) "L-proline:tRNAPro ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.15"^^xsd:string) "prolyl-transferRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.15"^^xsd:string) "prolyl-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.15"^^xsd:string) "prolyl-transfer ribonucleic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.15"^^xsd:string) "prolyl-s-RNA synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "proline-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.15"^^xsd:string) "prolinyl-tRNA ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.11"^^xsd:string) "SerRS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.11"^^xsd:string) "seryl-transfer ribonucleic acid synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "serine-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.11"^^xsd:string) "Catalysis of the reaction: ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.11"^^xsd:string) "serine translase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.11"^^xsd:string) "seryl-transfer RNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.11"^^xsd:string) "seryl-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.11"^^xsd:string) "L-serine:tRNASer ligase (AMP-forming)"^^xsd:string) AnnotationAssertion( "seryl-tRNA synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.3"^^xsd:string) "threonyl-transfer RNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.3"^^xsd:string) "threonyl-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.3"^^xsd:string) "threonyl ribonucleic synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.3"^^xsd:string) "Catalysis of the reaction: ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr)."^^xsd:string) AnnotationAssertion(rdfs:label "threonine-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.3"^^xsd:string) "threonine translase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.3"^^xsd:string) "threonyl-transfer ribonucleic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.3"^^xsd:string) "threonine-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.3"^^xsd:string) "L-threonine:tRNAThr ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.3"^^xsd:string) "TRS"^^xsd:string) AnnotationAssertion( "threonyl-tRNA synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.2"^^xsd:string) "tryptophanyl-transfer RNA synthetase activity"^^xsd:string) AnnotationAssertion( "tryptophanyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.2"^^xsd:string) "tryptophanyl-transfer ribonucleic synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.2"^^xsd:string) "tryptophanyl-transfer ribonucleic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.2"^^xsd:string) "tryptophan translase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.2"^^xsd:string) "L-tryptophan-tRNA(Trp) ligase (AMP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.2"^^xsd:string) "tryptophanyl-tRNA synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.2"^^xsd:string) "tryptophanyl-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.2"^^xsd:string) "L-tryptophan-tRNATrp ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.2"^^xsd:string) "tryptophanyl ribonucleic synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.2"^^xsd:string) "TrpRS activity"^^xsd:string) AnnotationAssertion(rdfs:label "tryptophan-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.2"^^xsd:string) "L-tryptophan:tRNATrp ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.2"^^xsd:string) "Catalysis of the reaction: ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophanyl-tRNA(Trp)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.1"^^xsd:string) "tyrosine tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.1"^^xsd:string) "tyrosyl-transfer ribonucleic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.1"^^xsd:string) "L-tyrosine-tRNA(Tyr) ligase (AMP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.1"^^xsd:string) "tyrosyl-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion( "tyrosyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.1"^^xsd:string) "L-tyrosine:tRNATyr ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "tyrosine-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.1"^^xsd:string) "tyrosyl-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.1"^^xsd:string) "tyrosine-transfer RNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.1"^^xsd:string) "tyrosine-transfer ribonucleate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.1"^^xsd:string) "L-tyrosine-tRNATyr ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.1"^^xsd:string) "tyrosine translase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.1"^^xsd:string) Annotation( "RHEA:10223"^^xsd:string) "Catalysis of the reaction: L-tyrosine + ATP + tRNA(Tyr) = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.1"^^xsd:string) "tyrosyl-transfer RNA synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.9"^^xsd:string) "L-valine:tRNAVal ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.9"^^xsd:string) "valine translase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.9"^^xsd:string) Annotation( "RHEA:10707"^^xsd:string) "Catalysis of the reaction: L-valine + ATP + tRNA(Val) = L-valyl-tRNA(Val) + AMP + diphosphate + 2 H(+)."^^xsd:string) AnnotationAssertion( "valyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.9"^^xsd:string) "valyl-transfer RNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.9"^^xsd:string) "valyl-transfer ribonucleic acid synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "valine-tRNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.9"^^xsd:string) "valine transfer ribonucleate ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.9"^^xsd:string) "valyl-transfer ribonucleate synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.11"^^xsd:string) "tryptamin 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.11"^^xsd:string) "tryptamine 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.11"^^xsd:string) "TDO"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.11"^^xsd:string) "L-tryptophan pyrrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.11"^^xsd:string) "tryptophan peroxidase activity"^^xsd:string) AnnotationAssertion( "indoleamine-pyrrole 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.11"^^xsd:string) "L-tryptophan 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.11"^^xsd:string) "L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.11"^^xsd:string) "tryptophan pyrrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.11"^^xsd:string) "Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.11"^^xsd:string) "tryptophan oxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tryptophan 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.11"^^xsd:string) "indolamine 2,3-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.20"^^xsd:string) "L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate; L-tryptophan and glyceraldehyde-3-phosphate-forming]"^^xsd:string) AnnotationAssertion(rdfs:label "tryptophan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:10535"^^xsd:string) "Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.20"^^xsd:string) "indoleglycerol phosphate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.20"^^xsd:string) "tryptophan synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.20"^^xsd:string) "L-serine hydro-lyase (adding indoleglycerol-phosphate)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.20"^^xsd:string) "tryptophan desmolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.20"^^xsd:string) "L-tryptophan synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tubulin-tyrosine ligase activity"^^xsd:string) AnnotationAssertion( "tubulinyl-tyrosine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.25"^^xsd:string) "alpha-tubulin:L-tyrosine ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.25"^^xsd:string) "TTL activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.25"^^xsd:string) "Catalysis of the reaction: ATP + detyrosinated alpha-tubulin + L-tyrosine = alpha-tubulin + ADP + phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10745161"^^xsd:string) "Catalysis of the hydroxylation of tyramine to form octopamine."^^xsd:string) AnnotationAssertion(rdfs:label "tyramine-beta hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.25"^^xsd:string) "L-tyrosine carboxy-lyase (tyramine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.25"^^xsd:string) "L-(-)-tyrosine apodecarboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tyrosine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.25"^^xsd:string) "L-tyrosine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.25"^^xsd:string) "L-tyrosine carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.25"^^xsd:string) "Catalysis of the reaction: L-tyrosine = tyramine + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.5"^^xsd:string) "glutamic-hydroxyphenylpyruvic transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.5"^^xsd:string) "L-tyrosine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.5"^^xsd:string) "phenylpyruvate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.5"^^xsd:string) "phenylalanine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.5"^^xsd:string) "phenylalanine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.5"^^xsd:string) "tyrosine-2-ketoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.5"^^xsd:string) "tyrosine-alpha-ketoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.5"^^xsd:string) "L-phenylalanine 2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.5"^^xsd:string) "phenylpyruvic acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.5"^^xsd:string) "glutamic phenylpyruvic aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-tyrosine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.5"^^xsd:string) "tyrosine-alpha-ketoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.5"^^xsd:string) "Catalysis of the reaction: L-tyrosine + 2-oxoglutarate = 4-hydroxyphenylpyruvate + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.5"^^xsd:string) "TyrAT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.5"^^xsd:string) "tyrosine transaminase activity"^^xsd:string) AnnotationAssertion( "tyrosine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.5"^^xsd:string) "phenylalanine-alpha-ketoglutarate transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10072378"^^xsd:string) Annotation( "http://www.bostonbiochem.com/E-301.html"^^xsd:string) "Catalysis of the reaction: a protein L-lysine + a ubiquitin + ATP = a protein-N-ubiquityl-lysine + AMP + diphosphate. This reaction is the activation of the C-terminal carboxyl group of ubiquitin by the formation of a high-energy thiolester bond in an ATP-dependent manner."^^xsd:string) AnnotationAssertion(rdfs:label "ubiquitin activating enzyme activity"^^xsd:string) AnnotationAssertion( "E1"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "E2"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "anaphase-promoting complex activity"^^xsd:string) AnnotationAssertion( "ubiquitin protein-ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.19"^^xsd:string) "ubiquitin:protein-lysine N-ligase (AMP-forming) activity"^^xsd:string) AnnotationAssertion( "ubiquitin ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.19"^^xsd:string) Annotation( "GOC:jh2"^^xsd:string) Annotation( "PMID:9635407"^^xsd:string) "Catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine."^^xsd:string) AnnotationAssertion( "ubiquitin-conjugating enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "ubiquitin-protein ligase activity"^^xsd:string) AnnotationAssertion( "E3"^^xsd:string) AnnotationAssertion( "ubiquitin-ligase activity"^^xsd:string) AnnotationAssertion( "ubiquitin protein ligase activity"^^xsd:string) AnnotationAssertion( "ubiquitin conjugating enzyme activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:15657442"^^xsd:string) "deubiquitylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.19.12"^^xsd:string) "ubiquitin C-terminal hydrolase activity"^^xsd:string) AnnotationAssertion( "UBP"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jh2"^^xsd:string) Annotation( "ISBN:0120793709"^^xsd:string) "Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin."^^xsd:string) AnnotationAssertion(rdfs:label "ubiquitin-specific protease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "ubiquitin hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:19261746"^^xsd:string) "deubiquitinase"^^xsd:string) AnnotationAssertion( "UCH2"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19188440"^^xsd:string) "deubiquitinating enzyme"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "uracil-DNA glycosylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "uracil DNA N-glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) Annotation( "PMID:9224623"^^xsd:string) "Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.9"^^xsd:string) "uridine monophosphate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.9"^^xsd:string) "uridylate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "uracil phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.9"^^xsd:string) "UMP:pyrophosphate phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.9"^^xsd:string) "UMP pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.9"^^xsd:string) "UMP diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.9"^^xsd:string) "UMP:diphosphate phospho-alpha-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.9"^^xsd:string) "UPRTase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.9"^^xsd:string) "uridine 5'-phosphate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.9"^^xsd:string) Annotation( "RHEA:13020"^^xsd:string) "Catalysis of the reaction: diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.9"^^xsd:string) "uridylic pyrophosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.3.3"^^xsd:string) "uricase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.3.3"^^xsd:string) "Catalysis of the reaction: urate + O2 + H2O = 5-hydroxyisourate + hydrogen peroxide."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.3.3"^^xsd:string) "urate:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "urate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.3.3"^^xsd:string) "uric acid oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.3.3"^^xsd:string) "uricase II activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.4.6"^^xsd:string) "urea carboxylase (hydrolyzing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.6"^^xsd:string) "ATP--urea amidolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.6"^^xsd:string) Annotation( "RHEA:20899"^^xsd:string) "Catalysis of the reaction: ATP + bicarbonate + urea = ADP + 2 H(+) + phosphate + urea-1-carboxylate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.6"^^xsd:string) "urea:carbon-dioxide ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.6"^^xsd:string) "urease (ATP-hydrolyzing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.6"^^xsd:string) "UCA activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.6"^^xsd:string) "urea carboxylase (hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.6"^^xsd:string) "urea amidolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.6"^^xsd:string) "urease (ATP-hydrolysing)"^^xsd:string) AnnotationAssertion(rdfs:label "urea carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.6"^^xsd:string) "UALase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.19"^^xsd:string) "(S)-ureidoglycolate amidohydrolase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.19"^^xsd:string) Annotation( "RHEA:19812"^^xsd:string) "Catalysis of the reaction: (S)-ureidoglycolate + H(2)O + 2 H(+) = CO(2) + glyoxylate + 2 NH(4)(+)."^^xsd:string) AnnotationAssertion(rdfs:label "ureidoglycolate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.48"^^xsd:string) "uridine phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.48"^^xsd:string) "uridine-cytidine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.48"^^xsd:string) "Catalysis of the reaction: ATP + uridine = ADP + UMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.48"^^xsd:string) "pyrimidine ribonucleoside kinase activity"^^xsd:string) AnnotationAssertion( "uridine kinase reaction"^^xsd:string) AnnotationAssertion(rdfs:label "uridine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.48"^^xsd:string) "uridine monophosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.48"^^xsd:string) "uridine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.48"^^xsd:string) "ATP:uridine 5'-phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.3"^^xsd:string) "UrdPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.3"^^xsd:string) "Catalysis of the reaction: uridine + phosphate = uracil + alpha-D-ribose 1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.3"^^xsd:string) "uridine:phosphate alpha-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.3"^^xsd:string) "pyrimidine phosphorylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "uridine phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.3"^^xsd:string) "UPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.3"^^xsd:string) "UPH"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.107"^^xsd:string) "S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.107"^^xsd:string) "S-adenosyl-L-methionine-dependent uroporphyrinogen III methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.107"^^xsd:string) "adenosylmethionine-uroporphyrinogen III methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.107"^^xsd:string) "urogen III methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.107"^^xsd:string) "uroporphyrinogen-III C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.107"^^xsd:string) "uroporphyrinogen methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.107"^^xsd:string) "Catalysis of the reaction: 2 S-adenosyl-L-methionine + uroporphyrin III = 2 S-adenosyl-L-homocysteine + precorrin-2."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.107"^^xsd:string) "CobA"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.107"^^xsd:string) "SUMT activity"^^xsd:string) AnnotationAssertion(rdfs:label "uroporphyrin-III C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.107"^^xsd:string) "SirA"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.107"^^xsd:string) "CysG"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.107"^^xsd:string) "uroporphyrinogen-III methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.107"^^xsd:string) "uroporphyrinogen-III methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.107"^^xsd:string) "uroporphyrinogen III methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.107"^^xsd:string) "S-adenosyl-L-methionine:uroporphyrinogen-III C-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.75"^^xsd:string) "URO-synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.75"^^xsd:string) "uroporphyrinogen isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.75"^^xsd:string) "uroporphyrinogen III cosynthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.75"^^xsd:string) Annotation( "RHEA:18968"^^xsd:string) "Catalysis of the reaction: hydroxymethylbilane = H(2)O + uroporphyrinogen III."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.75"^^xsd:string) "uroporphyrinogen-III cosynthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.75"^^xsd:string) "hydroxymethylbilane hydro-lyase (cyclizing; uroporphyrinogen-III-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.75"^^xsd:string) "hydroxymethylbilane hydro-lyase (cyclizing) activity"^^xsd:string) AnnotationAssertion(rdfs:label "uroporphyrinogen-III synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.75"^^xsd:string) "porphobilinogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.75"^^xsd:string) "uroporphyrinogen-III cosynthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.37"^^xsd:string) "porphyrinogen decarboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "uroporphyrinogen decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.37"^^xsd:string) "Catalysis of the reaction: uroporphyrinogen-III = coproporphyrinogen + 4 CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.37"^^xsd:string) "uroporphyrinogen-III carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.37"^^xsd:string) "porphyrinogen carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.37"^^xsd:string) "uroporphyrinogen-III carboxy-lyase (coproporphyrinogen-III-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.37"^^xsd:string) "uroporphyrinogen III decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.17.1.4"^^xsd:string) "Catalysis of the reaction: xanthine + NAD+ + H2O = urate + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.4"^^xsd:string) "xanthine/NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.4"^^xsd:string) "xanthine/NAD(+) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.4"^^xsd:string) "xanthine-NAD oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.4"^^xsd:string) "xanthine oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "xanthine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.4"^^xsd:string) "xanthine:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.4"^^xsd:string) "NAD-xanthine dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "xanthine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.2"^^xsd:string) "xanthine oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.2"^^xsd:string) "xanthine:O(2) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.2"^^xsd:string) "xanthine:O2 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.2"^^xsd:string) "xanthine:xanthine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.2"^^xsd:string) "schardinger enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.2"^^xsd:string) "Catalysis of the reaction: xanthine + H2O + O2 = urate + hydrogen peroxide."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.2"^^xsd:string) "xanthine:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.2"^^xsd:string) "Schardinger enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.2"^^xsd:string) "hypoxanthine-xanthine oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "xylulokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.17"^^xsd:string) "xylulokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.17"^^xsd:string) "D-xylulokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.17"^^xsd:string) "xylulose kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.17"^^xsd:string) Annotation( "RHEA:10967"^^xsd:string) "Catalysis of the reaction: D-xylulose + ATP = D-xylulose 5-phosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.17"^^xsd:string) "ATP:D-xylulose 5-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "enzyme inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Stops, prevents or reduces the activity of an enzyme."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stops, prevents or reduces the activity of dUTP pyrophosphatase."^^xsd:string) AnnotationAssertion(rdfs:label "dUTP pyrophosphatase inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "phospholipase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Stops, prevents or reduces the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a phospholipid."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "protein kinase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Stops, prevents or reduces the activity of a protein kinase, an enzyme which phosphorylates a protein."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclin-dependent protein serine/threonine kinase inhibitor activity"^^xsd:string) AnnotationAssertion( "cyclin dependent kinase inhibitor"^^xsd:string) AnnotationAssertion( "cyclin-dependent protein kinase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) "Stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase."^^xsd:string) AnnotationAssertion( "cyclin dependent protein kinase inhibitor activity"^^xsd:string) AnnotationAssertion( "cyclin-dependent kinase inhibitor"^^xsd:string) AnnotationAssertion( "CDK inhibitor"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "cAMP-dependent protein kinase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stops, prevents or reduces the activity of a cAMP-dependent protein kinase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "protein phosphatase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Stops, prevents or reduces the activity of a protein phosphatase, an enzyme that hydrolyzes phosphate groups from phosphorylated proteins."^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "phosphoprotein phosphatase inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "protein serine/threonine phosphatase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Stops, prevents or reduces the activity of a serine/threonine protein phosphatase, an enzyme that catalyzes the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides."^^xsd:string) AnnotationAssertion(rdfs:label "endopeptidase inhibitor activity"^^xsd:string) AnnotationAssertion( "proteinase inhibitor"^^xsd:string) AnnotationAssertion( "endoproteinase inhibitor"^^xsd:string) AnnotationAssertion( "alpha-2 macroglobulin"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "serine protease inhibitor activity"^^xsd:string) AnnotationAssertion( "serine proteinase inhibitor activity"^^xsd:string) AnnotationAssertion(rdfs:label "serine-type endopeptidase inhibitor activity"^^xsd:string) AnnotationAssertion( "serpin activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Stops, prevents or reduces the activity of a cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile."^^xsd:string) AnnotationAssertion( "thiol protease inhibitor"^^xsd:string) AnnotationAssertion(rdfs:label "cysteine-type endopeptidase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "cysteine protease inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "signal transducer activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response."^^xsd:string) AnnotationAssertion( "quorum sensing response regulator activity"^^xsd:string) AnnotationAssertion( "quorum sensing signal generator activity"^^xsd:string) AnnotationAssertion( "hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "asialoglycoprotein receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:11278827"^^xsd:string) Annotation( "PMID:7624395"^^xsd:string) Annotation( "Wikipedia:Asialoglycoprotein"^^xsd:string) "Receiving an asialoglycoprotein, and delivering the asialoglycoprotein into the cell via endocytosis. An asialoglycoprotein is a plasma glycoproteins from which the terminal sialic acid residue on their complex carbohydrate groups has been removed. The asialoglycoprotein receptor recognizes the terminal galactose and N-acetylgalactosamine units of the asialoglycoprotein, the receptor-ligand complex is internalized and transported to a sorting organelle where disassociation occurs before the receptor is recycled to the cell membrane."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:1325649"^^xsd:string) Annotation( "PMID:7493958"^^xsd:string) "Combining with an aryl hydrocarbon and transmitting the signal to initiate a change in cell activity. The aryl hydrocarbon receptor is a ligand-activated transcription factor which translocates to the nucleus to activate transcription upon ligand-binding."^^xsd:string) AnnotationAssertion(rdfs:label "aryl hydrocarbon receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "complement receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) Annotation( "PMID:11884446"^^xsd:string) "Combining with any component or product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "complement component C3a receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with the C3a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with the C3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "complement component C3b receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with the C5a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "complement component C5a receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "nuclear hormone receptor"^^xsd:string) AnnotationAssertion(rdfs:label "ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "GOC:txnOH"^^xsd:string) "Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "ligand-dependent nuclear receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "nuclear receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "ligand-dependent transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "juvenile hormone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:15475158"^^xsd:string) "Combining with juvenile hormone and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:19372015"^^xsd:string) "Combining with an androgen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an androgen response element in DNA in order to modulate transcription by RNA polymerase II."^^xsd:string) AnnotationAssertion(rdfs:label "androgen receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:yaf"^^xsd:string) "androgen response element binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:17689856"^^xsd:string) Annotation( "PMID:20920967"^^xsd:string) "Combining with a glucocorticoid and transmitting the signal within the cell trigger a change in cell activity or function."^^xsd:string) AnnotationAssertion(rdfs:label "glucocorticoid receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ecdysteroid hormone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:1653701"^^xsd:string) "Combining with an ecdysteroid hormone and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "retinoid-X receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "9-cis retinoic acid receptor activity"^^xsd:string) AnnotationAssertion( "RXR"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:17132853"^^xsd:string) "Combining with 9-cis retinoic acid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "Combining with thyroid hormone and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II."^^xsd:string) AnnotationAssertion(rdfs:label "thyroid hormone receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "non-G-protein-coupled 7TM receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "transmembrane signaling receptor activity"^^xsd:string) AnnotationAssertion( "non-G-protein coupled 7TM receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "transmembrane signalling receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "transmembrane receptor activity"^^xsd:string) AnnotationAssertion( "non G protein coupled 7TM receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "Wikipedia:Transmembrane_receptor"^^xsd:string) "Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:2466967"^^xsd:string) "Catalysis of the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine."^^xsd:string) AnnotationAssertion(rdfs:label "acetylcholine-activated cation-selective channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "nicotinic acetylcholine-activated cation-selective channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "ionotropic GABA receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "GABA-A receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8974333"^^xsd:string) "Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-A receptors function as chloride channels."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cytokine receptor activity"^^xsd:string) AnnotationAssertion( "IL receptor"^^xsd:string) AnnotationAssertion( "hematopoietin/interferon-class (D200-domain) cytokine receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "interleukin receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with ciliary neurotrophic factor (CNTF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "CNTF receptor activity"^^xsd:string) AnnotationAssertion( "gp130"^^xsd:string) AnnotationAssertion(rdfs:label "ciliary neurotrophic factor receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with erythropoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "erythropoietin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "granulocyte macrophage colony-stimulating factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "CSF2R"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with granulocyte macrophage colony-stimulating factor (GM-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "CSF-2 receptor activity"^^xsd:string) AnnotationAssertion( "granulocyte macrophage colony stimulating factor receptor activity"^^xsd:string) AnnotationAssertion( "GMC-SF receptor activity"^^xsd:string) AnnotationAssertion( "GM-CSF receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with granulocyte colony-stimulating factor (G-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "granulocyte colony stimulating factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "G-CSF receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "granulocyte colony-stimulating factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "CSF3R"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with a growth hormone and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "growth hormone receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:9607096"^^xsd:string) "Combining with an interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IFN receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "interferon receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "interferon-delta receptor activity"^^xsd:string) AnnotationAssertion( "interferon-omega receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0126896631"^^xsd:string) Annotation( "PMID:15546383"^^xsd:string) Annotation( "PMID:16681834"^^xsd:string) Annotation( "PR:000025848"^^xsd:string) "Combining with a type I interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families."^^xsd:string) AnnotationAssertion( "interferon-beta receptor activity"^^xsd:string) AnnotationAssertion( "interferon-epsilon receptor activity"^^xsd:string) AnnotationAssertion( "interferon-tau receptor activity"^^xsd:string) AnnotationAssertion( "interferon-alpha/beta receptor activity"^^xsd:string) AnnotationAssertion( "interferon-zeta receptor activity"^^xsd:string) AnnotationAssertion( "interferon-kappa receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "type I interferon receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "type I IFN receptor activity"^^xsd:string) AnnotationAssertion( "interferon-alpha receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0126896631"^^xsd:string) Annotation( "PMID:15546383"^^xsd:string) "Combining with interferon-gamma (a type II interferon) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IFNG receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "interferon-gamma receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IFN-gamma receptor activity"^^xsd:string) AnnotationAssertion( "type II interferon receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "IL-1R"^^xsd:string) AnnotationAssertion( "IL-1 receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-1 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "interleukin-1, Type I, activating binding"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-1, Type I, activating receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "interleukin-1 Type I receptor activity"^^xsd:string) AnnotationAssertion( "IL-1 type I, activating binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "interleukin-1 activating receptor activity"^^xsd:string) AnnotationAssertion( "IL-1 type I, activating receptor"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15062641"^^xsd:string) Annotation( "PMID:18613828"^^xsd:string) "Combining with interleukin-1 to initiate a change in cell activity via signaling pathways and mediated by adaptor proteins."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:15062641"^^xsd:string) Annotation( "PMID:18613828"^^xsd:string) "Combining with interleukin-1 to initiate a change in cell activity by inhibiting the activity of type I interleukin receptors."^^xsd:string) AnnotationAssertion( "IL-1 type II, blocking receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "interleukin-1 blocking receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-1, Type II, blocking receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "interleukin-1 Type II receptor activity"^^xsd:string) AnnotationAssertion( "IL-1 type II, blocking binding"^^xsd:string) AnnotationAssertion( "interleukin-1, Type II, blocking binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-2 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-2 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-2 receptor activity"^^xsd:string) AnnotationAssertion( "IL-2R"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-3 receptor activity"^^xsd:string) AnnotationAssertion( "IL-3R"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-3 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-3 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "IL-4R"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-4 receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-4 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-4 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-5 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-5 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-5 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "IL-5R"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "gp130"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-6 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "IL-6R"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-6 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-6 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "IL-7R"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-7 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-7 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-7 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-8 receptor activity"^^xsd:string) AnnotationAssertion( "IL-8R"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-8 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-8 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-9 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-9 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "IL-9R"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-9 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-10 receptor activity"^^xsd:string) AnnotationAssertion( "IL-10R"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-10 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-10 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "IL-11R"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-11 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "gp130"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-11 receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-11 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with leukemia inhibitory factor (LIF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "leukemia inhibitory factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "LIF receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "leukemia inhibitory factor receptor beta-protein activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oncostatin-M receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with oncostatin-M and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with prolactin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "prolactin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Epstein-Barr Virus-induced receptor activity"^^xsd:string) AnnotationAssertion( "EBV-induced receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "receptor activity, G-protein coupled"^^xsd:string) AnnotationAssertion( "G protein coupled receptor activity"^^xsd:string) AnnotationAssertion( "orphan GPCR activity"^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled receptor activity"^^xsd:string) AnnotationAssertion( "G protein linked receptor activity"^^xsd:string) AnnotationAssertion( "RDC1 receptor activity"^^xsd:string) AnnotationAssertion( "Mas proto-oncogene receptor activity"^^xsd:string) AnnotationAssertion( "G-protein linked receptor activity"^^xsd:string) AnnotationAssertion( "SREB receptor"^^xsd:string) AnnotationAssertion( "orphan G protein coupled receptor activity"^^xsd:string) AnnotationAssertion( "orphan G-protein coupled receptor activity"^^xsd:string) AnnotationAssertion( "super conserved receptor expressed in brain receptor activity"^^xsd:string) AnnotationAssertion( "GPCR activity"^^xsd:string) AnnotationAssertion( "G-protein-coupled receptor activity"^^xsd:string) AnnotationAssertion( "G-protein coupled receptor activity, unknown ligand"^^xsd:string) AnnotationAssertion( "ligand-dependent GPCR activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "Wikipedia:GPCR"^^xsd:string) Annotation( "http://www.iuphar-db.org"^^xsd:string) "Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9755289"^^xsd:string) "Catalysis of the transmembrane transfer of a cation by a channel that opens when extracellular ATP has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion(Annotation( "PMID:9755289"^^xsd:string) "P2X receptor"^^xsd:string) AnnotationAssertion( "purinoceptor"^^xsd:string) AnnotationAssertion( "purinoreceptor"^^xsd:string) AnnotationAssertion(rdfs:label "extracellular ATP-gated cation channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mating-type factor pheromone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "Combining with a mating-type factor pheromone to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "class D G-protein-coupled receptor activity"^^xsd:string) AnnotationAssertion( "class D GPCR activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with the mating-type a-factor pheromone to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "mating-type a-factor pheromone receptor activity"^^xsd:string) AnnotationAssertion( "class D G-protein coupled receptor activity"^^xsd:string) AnnotationAssertion( "class D G protein coupled receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mating-type alpha-factor pheromone receptor activity"^^xsd:string) AnnotationAssertion( "class D G-protein-coupled receptor activity"^^xsd:string) AnnotationAssertion( "class D GPCR activity"^^xsd:string) AnnotationAssertion( "class D G protein coupled receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with the mating-type alpha-factor pheromone to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "class D G-protein coupled receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "adrenergic receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "IUPHAR_GPCR:1274"^^xsd:string) "Combining with epinephrine or norepinephrine and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex."^^xsd:string) AnnotationAssertion( "adrenoceptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-adrenergic receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "IUPHAR_GPCR:1274"^^xsd:string) "Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha-adrenergic receptors."^^xsd:string) AnnotationAssertion( "alpha adrenoceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "IUPHAR_GPCR:1274"^^xsd:string) "Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha1-adrenergic receptors; the activity involves transmitting the signal to the Gq alpha subunit of a heterotrimeric G protein."^^xsd:string) AnnotationAssertion( "alpha1 adrenoceptor"^^xsd:string) AnnotationAssertion(rdfs:label "alpha1-adrenergic receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "alpha2 adrenoceptor"^^xsd:string) AnnotationAssertion(rdfs:label "alpha2-adrenergic receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "IUPHAR_GPCR:1274"^^xsd:string) "Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha2-adrenergic receptors; the activity involves transmitting the signal to the Gi alpha subunit of a heterotrimeric G protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-adrenergic receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "IUPHAR_GPCR:1274"^^xsd:string) "Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors; the activity involves transmitting the signal to the Gs alpha subunit of a heterotrimeric G protein."^^xsd:string) AnnotationAssertion( "beta adrenoceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta1-adrenergic receptor activity"^^xsd:string) AnnotationAssertion( "beta1 adrenoceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "IUPHAR_GPCR:1274"^^xsd:string) "Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta1-adrenergic receptors."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "IUPHAR_GPCR:1274"^^xsd:string) "Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta2-adrenergic receptors."^^xsd:string) AnnotationAssertion( "beta2 adrenoceptor"^^xsd:string) AnnotationAssertion(rdfs:label "beta2-adrenergic receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Combining with anaphylatoxin to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "anaphylatoxin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "C3a anaphylatoxin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with anaphylatoxin C3a to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "C5a anaphylatoxin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with anaphylatoxin C5a to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:10977869"^^xsd:string) "An angiotensin receptor activity that acts via Gi protein coupling and cGMP (NO) generation, and may also act via additional signaling mechanisms."^^xsd:string) AnnotationAssertion(rdfs:label "angiotensin type II receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Combining with bombesin to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "bombesin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bradykinin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Combining with bradykinin to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcitonin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:21649645"^^xsd:string) "Combining with calcitonin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "cannabinoid receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "endocannabinoid receptor activity"^^xsd:string) AnnotationAssertion( "cannaboid receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "IUPHAR_GPCR:1279"^^xsd:string) Annotation( "Wikipedia:Cannabinoid"^^xsd:string) "Combining with a cannabinoid to initiate a change in cell activity. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "IUPHAR_GPCR:1280"^^xsd:string) Annotation( "PMID:12183377"^^xsd:string) Annotation( "PMID:8662823"^^xsd:string) Annotation( "http://en.wikipedia.org/wiki/Chemokine"^^xsd:string) "Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria."^^xsd:string) AnnotationAssertion(rdfs:label "chemokine receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:9835394"^^xsd:string) "Combining with cholecystokinin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity. Cholecystokinin can act as a neuropeptide or as a gastrointestinal hormone."^^xsd:string) AnnotationAssertion(rdfs:label "cholecystokinin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PR:000005110"^^xsd:string) Annotation( "Wikipedia:Cholecystokinin"^^xsd:string) "CCK receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IUPHAR_GPCR:1282"^^xsd:string) "Combining with the neurotransmitter dopamine to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "dopamine neurotransmitter receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "eicosanoid receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "icosanoid receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "Combining with an icosanoid to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Combining with a prostanoid, any compound based on or derived from the prostanoate structure, to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "prostanoid receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "prostaglandin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Combining with a prostaglandin (PG) to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "prostaglandin D receptor activity"^^xsd:string) AnnotationAssertion( "PGD(2) receptor activity"^^xsd:string) AnnotationAssertion( "PGD receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Combining with prostaglandin D (PGD(2)) to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Combining with prostaglandin E (PGE(2)) to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "PGE(2) receptor activity"^^xsd:string) AnnotationAssertion( "PGE receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "prostaglandin E receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Combining with prostaglandin F (PGF (2-alpha)) to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "PGF(2-alpha) receptor activity"^^xsd:string) AnnotationAssertion( "PGF receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "prostaglandin F receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Combining with a thromboxane (TXA) to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "TXA receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "thromboxane receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:15242977"^^xsd:string) "TXA2 receptor activity"^^xsd:string) AnnotationAssertion( "TXA(2) receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "thromboxane A2 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Combining with thromboxane A2 (TXA(2)) and transmitting the signal across the membrane to activate an associated G-protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "endothelin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "IUPHAR_GPCR:1283"^^xsd:string) Annotation( "IUPHAR_RECEPTOR:2263"^^xsd:string) Annotation( "IUPHAR_RECEPTOR:2265"^^xsd:string) "Combining with endothelin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:8582288"^^xsd:string) "endothelin-A receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:8582288"^^xsd:string) "endothelin-B receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "follicle-stimulating hormone receptor activity"^^xsd:string) AnnotationAssertion( "FSH receptor activity"^^xsd:string) AnnotationAssertion( "follicle stimulating hormone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with follicle-stimulating hormone to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "lutropin receptor"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "PMID:18848524"^^xsd:string) Annotation( "PMID:1922095"^^xsd:string) "Combining with luteinizing hormone (also called lutropin) to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "PMID:18848524"^^xsd:string) "LH receptor"^^xsd:string) AnnotationAssertion(Annotation( "PMID:1922095"^^xsd:string) "lutropin-choriogonadotropic hormone receptor"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18848524"^^xsd:string) "LHR"^^xsd:string) AnnotationAssertion(rdfs:label "luteinizing hormone receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "GABA-B receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "IUPHAR_RECEPTOR:1276"^^xsd:string) Annotation( "Wikipedia:GABAB_receptor"^^xsd:string) "Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled GABA receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "Wikipedia:GABAB_receptor"^^xsd:string) "metabotropic GABA receptor"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "galanin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Combining with galanin to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:22438981"^^xsd:string) "Combining with glucagon and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."^^xsd:string) AnnotationAssertion(rdfs:label "glucagon receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "gonadotropin-releasing hormone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "gonadotrophin-releasing hormone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with gonadotropin-releasing hormone to initiate a change in cell activity. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus."^^xsd:string) AnnotationAssertion( "GnRH receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "histamine receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Combining with histamine to initiate a change in cell activity. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "ionotropic glutamate receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:10049997"^^xsd:string) Annotation( "PMID:8804111"^^xsd:string) "An ionotropic glutamate receptor activity that exhibits fast gating by glutamate and acts by opening a cation channel permeable to sodium, potassium, and, in the absence of a GluR2 subunit, calcium."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity"^^xsd:string) AnnotationAssertion( "AMPA receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "NMDA receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:10049997"^^xsd:string) "An ionotropic glutamate receptor activity that exhibits slow gating by glutamate, acts by opening a nonselective cation channel, and can be activated by L-aspartate."^^xsd:string) AnnotationAssertion(rdfs:label "N-methyl-D-aspartate selective glutamate receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Combining with a leukotriene to initiate a change in cell activity. Leukotrienes are pharmacologically active substances with a set of three conjugated double bonds; some contain a peptide group based on cysteine."^^xsd:string) AnnotationAssertion(rdfs:label "leukotriene receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "melanocortin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Combining with melanocortin to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "adrenocorticotropin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Combining with corticotropin to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "corticotropin receptor activity"^^xsd:string) AnnotationAssertion( "adrenocorticotropic hormone receptor activity"^^xsd:string) AnnotationAssertion( "ACTH receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-endorphin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "Wikipedia:Beta-endorphin"^^xsd:string) "Combining with beta-endorphin, and transmitting the signal across the membrane by activating an associated G-protein. Beta-endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor proopiomelanocortin (POMC)."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "mu-opioid receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "MSH receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "melanocyte-stimulating hormone receptor activity"^^xsd:string) AnnotationAssertion( "MSHR activity"^^xsd:string) AnnotationAssertion( "melanocyte stimulating hormone receptor activity"^^xsd:string) AnnotationAssertion( "melanophore-stimulating hormone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:7581459"^^xsd:string) "Combining with melanocyte-stimulating hormone to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Combining with an N-formyl peptide to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "N-formyl peptide receptor activity"^^xsd:string) AnnotationAssertion( "Fmet-leu-phe receptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:9315606"^^xsd:string) "Combining with neuropeptide Y to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "neuropeptide Y receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19135896"^^xsd:string) Annotation( "PMID:21041441"^^xsd:string) "odorant receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "olfactory receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:19135896"^^xsd:string) Annotation( "PMID:21041441"^^xsd:string) "Combining with an odorant and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity in response to detection of smell."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:60598"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:20494127"^^xsd:string) "Combining with an opioid (any narcotic derived from or resembling opium), and transmitting the signal across the membrane by activating an associated G-protein."^^xsd:string) AnnotationAssertion(rdfs:label "opioid receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "octopamine receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:17134"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Combining with the biogenic amine octopamine to initiate a change in cell activity. Octopamine is found in both vertebrates and invertebrates and can have properties both of a hormone and a neurotransmitter and acts as an adrenergic agonist."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Combining with oxytocin to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "oxytocin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with parathyroid hormone to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "parathyroid hormone receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "platelet activating factor receptor activity"^^xsd:string) AnnotationAssertion( "PAF receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with platelet activating factor to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:28790"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates."^^xsd:string) AnnotationAssertion( "G protein coupled serotonin receptor activity"^^xsd:string) AnnotationAssertion( "G-protein-coupled serotonin receptor activity"^^xsd:string) AnnotationAssertion( "5-hydroxytryptamine receptor"^^xsd:string) AnnotationAssertion( "5-HT receptor"^^xsd:string) AnnotationAssertion(rdfs:label "serotonin receptor activity"^^xsd:string) AnnotationAssertion( "G-protein coupled serotonin receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "Wikipedia:Somatostatin"^^xsd:string) "Combining with somatostatin to initiate a change in cell activity. Somatostatin is a peptide hormone that regulates the endocrine system by signaling via G-protein coupled somatostatin receptors. Somatostatin has two active forms produced by proteolytic cleavage: a 14 amino acid peptide (SST-14) and a 28 amino acid peptide (SST-28)."^^xsd:string) AnnotationAssertion(rdfs:label "somatostatin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "Wikipedia:Somatostatin"^^xsd:string) "growth hormone-inhibiting hormone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "Wikipedia:Somatostatin"^^xsd:string) "SRIF receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "Wikipedia:Somatostatin"^^xsd:string) "GHIH receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "Wikipedia:Somatostatin"^^xsd:string) "somatotrophin release inhibiting factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "Wikipedia:Somatostatin"^^xsd:string) "SST receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tachykinin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:7639617"^^xsd:string) Annotation( "Wikipedia:Tachykinin"^^xsd:string) "Combining with a tachykinin neuropeptide and transmitting the signal across the membrane by activating an associated G-protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "thyrotropin receptor"^^xsd:string) AnnotationAssertion( "thyroid stimulating hormone receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "thyroid-stimulating hormone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with thyroid-stimulating hormone to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "TSH receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thyrotropin-releasing hormone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with thyrotropin-releasing hormone to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:2678449"^^xsd:string) Annotation( "PMID:3011819"^^xsd:string) "Combining selectively with transferrin, and delivering transferrin into the cell via endocytosis. Transferrin is a major iron carrier protein in vertebrates."^^xsd:string) AnnotationAssertion(rdfs:label "transferrin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "vasoactive intestinal polypeptide receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with vasoactive intestinal polypeptide to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Combining with vasopressin to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "vasopressin activated calcium mobilizing receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "vasopressin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.48"^^xsd:string) "Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "transmembrane receptor protein tyrosine phosphatase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Eph receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "ephrin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9530499"^^xsd:string) "Combining with an ephrin to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "GPI-linked Eph receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "GPI-linked ephrin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9530499"^^xsd:string) "Combining with a GPI-anchored ephrin to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "transmembrane-ephrin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9530499"^^xsd:string) "Combining with a transmembrane ephrin to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "transmembrane-Eph receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "TGF-alpha receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "epidermal growth factor-activated receptor activity"^^xsd:string) AnnotationAssertion( "transforming growth factor-alpha receptor activity"^^xsd:string) AnnotationAssertion( "EGF receptor activity"^^xsd:string) AnnotationAssertion( "EGFR"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "epidermal growth factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Combining with an epidermal growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "FGF receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "fibroblast growth factor receptor activity"^^xsd:string) AnnotationAssertion( "FGFR"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "FGF-activated receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with a fibroblast growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "fibroblast growth factor-activated receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "HGF-activated receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "hepatocyte growth factor-activated receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "hepatocyte growth factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with hepatocyte growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "HGF receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "insulin-activated receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "insulin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Combining with insulin and transmitting the signal across the plasma membrane to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "insulin-like growth factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with insulin-like growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "IGF receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "insulin-like growth factor-activated receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "IGF-activated receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with macrophage colony-stimulating factor (M-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate."^^xsd:string) AnnotationAssertion( "CSF-1"^^xsd:string) AnnotationAssertion( "Fms"^^xsd:string) AnnotationAssertion( "macrophage colony stimulating factor receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "macrophage colony-stimulating factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "M-CSF receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "platelet-derived growth factor-activated receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with platelet-derived growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "PDGF-activated receptor activity"^^xsd:string) AnnotationAssertion( "PDGFR activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "platelet-derived growth factor receptor activity"^^xsd:string) AnnotationAssertion( "PDGF receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "PDGF alpha-receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10372961"^^xsd:string) "alphaPDGF receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "platelet-derived growth factor alpha-receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:1657917"^^xsd:string) "Combining with platelet-derived growth factor isoform PDGF-AA, PDGF-BB or PDGF-AB to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "PDGF beta-receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "platelet-derived growth factor beta-receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10372961"^^xsd:string) "betaPDGF receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:1657917"^^xsd:string) "Combining with platelet-derived growth factor isoform PDGF-BB or PDGF-AB to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PR:000009345"^^xsd:string) "KIT"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:10698217"^^xsd:string) "Combining with stem cell factor (SCF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. Stem cell factor is a cytokine that stimulates mast cell growth and differentiation."^^xsd:string) AnnotationAssertion(rdfs:label "stem cell factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PR:000009345"^^xsd:string) "KL receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PR:000009345"^^xsd:string) "KIT ligand receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PR:000009345"^^xsd:string) "SCF receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "VEGF-activated receptor activity"^^xsd:string) AnnotationAssertion( "VEGFR activity"^^xsd:string) AnnotationAssertion(rdfs:label "vascular endothelial growth factor-activated receptor activity"^^xsd:string) AnnotationAssertion( "VEGF receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "vascular endothelial growth factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with a vascular endothelial growth factor (VEGF) and transmitting the signal across the plasma membrane to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate."^^xsd:string) AnnotationAssertion( "TGFbeta receptor activity"^^xsd:string) AnnotationAssertion( "TGF-beta receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "TGFbeta-activated receptor activity"^^xsd:string) AnnotationAssertion( "TGFbetaR"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "transforming growth factor beta receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "transforming growth factor beta-activated receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "Reactome:REACT_6945.1"^^xsd:string) "Combining with a complex of transforming growth factor beta and a type II TGF-beta receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of TGF-beta signals."^^xsd:string) AnnotationAssertion( "type I TGF-beta receptor activity"^^xsd:string) AnnotationAssertion( "type I TGFbeta receptor activity"^^xsd:string) AnnotationAssertion( "transforming growth factor beta ligand binding to type I receptor"^^xsd:string) AnnotationAssertion(rdfs:label "transforming growth factor beta receptor activity, type I"^^xsd:string) AnnotationAssertion( "type I transforming growth factor beta receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type II TGFbeta receptor activity"^^xsd:string) AnnotationAssertion( "type II TGF-beta receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "transforming growth factor beta receptor activity, type II"^^xsd:string) AnnotationAssertion( "transforming growth factor beta ligand binding to type II receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "Reactome:REACT_6872.1"^^xsd:string) "Combining with transforming growth factor beta to initiate a change in cell activity; upon ligand binding, binds to and catalyzes the phosphorylation of a type I TGF-beta receptor."^^xsd:string) AnnotationAssertion( "type II transforming growth factor beta receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "http://www.mercksource.com/"^^xsd:string) "Combining with a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth, and transmitting the signal to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "neurotrophin receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "tumor necrosis factor receptor activity, type II"^^xsd:string) AnnotationAssertion(rdfs:label "tumor necrosis factor-activated receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "tumor necrosis factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "http://lookwayup.com/"^^xsd:string) "Combining with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages, to initiate a change in cell function."^^xsd:string) AnnotationAssertion( "TNF receptor activity, type I"^^xsd:string) AnnotationAssertion( "tumor necrosis factor receptor activity, type I"^^xsd:string) AnnotationAssertion( "TNF receptor activity"^^xsd:string) AnnotationAssertion( "NGF/TNF (6 C-domain) receptor activity"^^xsd:string) AnnotationAssertion( "TNF receptor activity, type II"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Sensing extracellular osmolarity to initiate a change in cell activity, and spanning the membrane of the cell."^^xsd:string) AnnotationAssertion(rdfs:label "osmosensor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "death receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "apoptosis-activating receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:ecd"^^xsd:string) Annotation( "GOC:mtg_apoptosis"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) Annotation( "PMID:10209153"^^xsd:string) "Combining with an extracellular messenger (called a death ligand), and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic or necrotic cell death."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:ecd"^^xsd:string) Annotation( "PMID:10209153"^^xsd:string) "Combining with an extracellular messenger (death ligand) without transmission of the signal. Decoy death receptors compete with death receptors for ligand binding, and do not initiate apoptosis."^^xsd:string) AnnotationAssertion(rdfs:label "decoy death receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "low-density lipoprotein receptor activity"^^xsd:string) AnnotationAssertion( "LDL receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein into the cell via endocytosis."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "LDLR activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "netrin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:15960985"^^xsd:string) "Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "netrin receptor activity involved in chemorepulsion"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "netrin receptor activity involved in negative chemotaxis"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell away from a higher concentration of netrin."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "repulsive netrin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:11790542"^^xsd:string) Annotation( "PMID:12379907"^^xsd:string) Annotation( "PMID:12621157"^^xsd:string) Annotation( "PMID:20981357"^^xsd:string) "Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, beta-amyloid fibrils, and advanced glycation end products (AGEs)."^^xsd:string) AnnotationAssertion(rdfs:label "scavenger receptor activity"^^xsd:string) AnnotationAssertion( "macrophage receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "KDEL sequence binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a KDEL sequence, the C terminus tetrapeptide sequence Lys-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum."^^xsd:string) AnnotationAssertion( "KDEL receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with the signal recognition particle."^^xsd:string) AnnotationAssertion( "docking protein"^^xsd:string) AnnotationAssertion(rdfs:label "signal recognition particle binding"^^xsd:string) AnnotationAssertion( "signal recognition particle receptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "signal sequence binding"^^xsd:string) AnnotationAssertion( "signal sequence receptor"^^xsd:string) AnnotationAssertion( "protein signal sequence binding"^^xsd:string) AnnotationAssertion( "leader sequence binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a signal sequence, a specific peptide sequence found on protein precursors or mature proteins that dictates where the mature protein is localized."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "NES receptor"^^xsd:string) AnnotationAssertion(rdfs:label "nuclear export signal receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:11743003"^^xsd:string) "Combining with a nuclear export signal (NES) to mediate transport of the NES-containing protein through the nuclear pore to the cytoplasm."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:14709540"^^xsd:string) "peroxisomal targeting signal 1 (PTS1) binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:11687502"^^xsd:string) "Interacting selectively and non-covalently with a type 1 peroxisome targeting signal, a tripeptide with the consensus sequence (S/A/C)-(K/R/H)-L."^^xsd:string) AnnotationAssertion( "peroxisome targeting signal-1 receptor"^^xsd:string) AnnotationAssertion( "peroxisome targeting signal-1 binding"^^xsd:string) AnnotationAssertion(rdfs:label "peroxisome matrix targeting signal-1 binding"^^xsd:string) AnnotationAssertion( "PEX5"^^xsd:string) AnnotationAssertion( "PTS1 receptor"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14709540"^^xsd:string) "PTS1 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "peroxisome targeting signal-2 receptor"^^xsd:string) AnnotationAssertion( "peroxisome targeting signal-2 binding"^^xsd:string) AnnotationAssertion( "PEX7"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14709540"^^xsd:string) "PTS2 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:11687502"^^xsd:string) "Interacting selectively and non-covalently with a type 2 peroxisome targeting signal, a nonapeptide with a broad consensus sequence of (R/K)-(L/V/I)-(XXXXX)-(H/Q)-(L/A/F)."^^xsd:string) AnnotationAssertion( "PTS2 receptor"^^xsd:string) AnnotationAssertion(rdfs:label "peroxisome matrix targeting signal-2 binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14709540"^^xsd:string) "peroxisomal targeting signal 2 (PTS2) binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:2970671"^^xsd:string) "Combining with a laminin, a glycoprotein that constitutes the majority of proteins in the basement membrane, to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "laminin receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:9521906"^^xsd:string) "Combining with the extracellular matrix ligand tiggrin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "tiggrin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Conveys a signal from an upstream receptor or intracellular signal transducer, converting the signal into a form where it can ultimately trigger a change in the state or activity of a cell."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "intracellular signal transducer activity"^^xsd:string) AnnotationAssertion(rdfs:label "receptor signaling protein activity"^^xsd:string) AnnotationAssertion( "receptor signalling protein activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "transmembrane receptor protein tyrosine kinase adaptor protein activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_MIT_16mar07"^^xsd:string) Annotation( "PMID:10502414"^^xsd:string) Annotation( "PMID:20565848"^^xsd:string) "The binding activity of a molecule that brings together a transmembrane receptor protein tyrosine kinase and one or more other molecules, permitting them to function in a coordinated way."^^xsd:string) AnnotationAssertion(rdfs:label "transmembrane receptor protein tyrosine kinase adaptor activity"^^xsd:string) AnnotationAssertion( "transmembrane receptor protein tyrosine kinase docking protein activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "SH3/SH2 adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:so"^^xsd:string) "Interacting selectively and non-covalently and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68)."^^xsd:string) AnnotationAssertion( "SH3/SH2 adaptor protein activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "transforming growth factor beta receptor, cytoplasmic mediator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Activity of any of the molecules that transmit the signal from a TGF-beta receptor through the cytoplasm to the nucleus."^^xsd:string) AnnotationAssertion( "TGFbeta receptor, cytoplasmic mediator activity"^^xsd:string) AnnotationAssertion( "TGF-beta receptor, cytoplasmic mediator activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12511654"^^xsd:string) Annotation( "PMID:15213240"^^xsd:string) Annotation( "PMID:9405336"^^xsd:string) "The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently."^^xsd:string) AnnotationAssertion(rdfs:label "MAP-kinase scaffold activity"^^xsd:string) AnnotationAssertion( "MAP-kinase scaffold protein activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "protein kinase C eta binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) "PKC delta binding"^^xsd:string) AnnotationAssertion( "PKC binding"^^xsd:string) AnnotationAssertion(rdfs:label "protein kinase C binding"^^xsd:string) AnnotationAssertion( "protein kinase C delta binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with protein kinase C."^^xsd:string) AnnotationAssertion( "PKC alpha binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) "PKC eta binding"^^xsd:string) AnnotationAssertion( "protein kinase C alpha binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Modulates the rate of GTP hydrolysis by a small monomeric GTPase."^^xsd:string) AnnotationAssertion( "small GTPase regulatory/interacting protein activity"^^xsd:string) AnnotationAssertion(rdfs:label "small GTPase regulator activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "guanyl-nucleotide release factor activity"^^xsd:string) AnnotationAssertion( "GEF"^^xsd:string) AnnotationAssertion(rdfs:label "guanyl-nucleotide exchange factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase."^^xsd:string) AnnotationAssertion( "guanyl-nucleotide releasing factor"^^xsd:string) AnnotationAssertion( "GNRP"^^xsd:string) AnnotationAssertion( "GDS"^^xsd:string) AnnotationAssertion( "GDP-dissociation stimulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "ARF guanyl-nucleotide exchange factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stimulates the exchange of guanyl nucleotides associated with the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ran family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase."^^xsd:string) AnnotationAssertion(rdfs:label "Ran guanyl-nucleotide exchange factor activity"^^xsd:string) AnnotationAssertion( "RCC1"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ras superfamily. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase."^^xsd:string) AnnotationAssertion(rdfs:label "Ras guanyl-nucleotide exchange factor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Rho guanine nucleotide exchange factor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rho family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase."^^xsd:string) AnnotationAssertion(rdfs:label "Rho guanyl-nucleotide exchange factor activity"^^xsd:string) AnnotationAssertion( "RhoGEF"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Sar guanyl-nucleotide exchange factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Sar family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_MIT_16mar07"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "The binding activity of a molecule that brings together a guanyl-nucleotide exchange factor and one or more other proteins, permitting them to function in a coordinated way."^^xsd:string) AnnotationAssertion(rdfs:label "guanyl-nucleotide exchange factor adaptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "GDI"^^xsd:string) AnnotationAssertion(rdfs:label "GDP-dissociation inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "Rab GDP-dissociation inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Prevents the dissociation of GDP from the small GTPase Rab, thereby preventing GTP from binding."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Rho GDP-dissociation inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Prevents the dissociation of GDP from the small GTPase Rho, thereby preventing GTP from binding."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "GIP"^^xsd:string) AnnotationAssertion(rdfs:label "GTPase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "GAP activity"^^xsd:string) AnnotationAssertion(rdfs:label "GTPase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:pg"^^xsd:string) "Rab GAP activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Increases the rate of GTP hydrolysis by a GTPase of the Rab family."^^xsd:string) AnnotationAssertion(rdfs:label "Rab GTPase activator activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Ran GTPase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Increases the rate of GTP hydrolysis by a GTPase of the Ran family."^^xsd:string) AnnotationAssertion(Annotation( "GOC:pg"^^xsd:string) "Ran GAP activity"^^xsd:string) AnnotationAssertion( "RanGAP"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:pg"^^xsd:string) "Ras GAP activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Increases the rate of GTP hydrolysis by a GTPase of the Ras superfamily."^^xsd:string) AnnotationAssertion(rdfs:label "Ras GTPase activator activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:pg"^^xsd:string) "Rho GAP activity"^^xsd:string) AnnotationAssertion(rdfs:label "Rho GTPase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Increases the rate of GTP hydrolysis by a GTPase of the Rho family."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:pg"^^xsd:string) "Sar GAP activity"^^xsd:string) AnnotationAssertion(rdfs:label "Sar GTPase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Increases the rate of GTP hydrolysis by a GTPase of the Sar family."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "receptor-associated protein activity"^^xsd:string) AnnotationAssertion(rdfs:label "receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:ceb"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function."^^xsd:string) AnnotationAssertion( "receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "FGF receptor binding"^^xsd:string) AnnotationAssertion( "fibroblast growth factor"^^xsd:string) AnnotationAssertion( "FGFR binding"^^xsd:string) AnnotationAssertion( "FGFR ligand"^^xsd:string) AnnotationAssertion(rdfs:label "fibroblast growth factor receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) "Interacting selectively and non-covalently with the fibroblast growth factor receptor (FGFR)."^^xsd:string) AnnotationAssertion( "fibroblast growth factor receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 1 fibroblast growth factor receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "GOC:fb_curators"^^xsd:string) "Interacting selectively and non-covalently with the type 1 fibroblast growth factor receptor (FGFR1)."^^xsd:string) AnnotationAssertion( "breathless binding"^^xsd:string) AnnotationAssertion( "type 1 fibroblast growth factor receptor ligand"^^xsd:string) AnnotationAssertion( "breathless ligand"^^xsd:string) AnnotationAssertion( "FGFR1 ligand"^^xsd:string) AnnotationAssertion( "FGFR1 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "frizzled ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "PR:000001315"^^xsd:string) "Interacting selectively and non-covalently with the frizzled (fz) receptor."^^xsd:string) AnnotationAssertion( "fz binding"^^xsd:string) AnnotationAssertion(rdfs:label "frizzled binding"^^xsd:string) AnnotationAssertion( "fz ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "fz2 binding"^^xsd:string) AnnotationAssertion( "frizzled-2 ligand"^^xsd:string) AnnotationAssertion( "fz2 ligand"^^xsd:string) AnnotationAssertion(rdfs:label "frizzled-2 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "PR:000007719"^^xsd:string) "Interacting selectively and non-covalently with frizzled-2 (fz2)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type 2 fibroblast growth factor receptor ligand"^^xsd:string) AnnotationAssertion( "FGFR2 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:fb_curators"^^xsd:string) "Interacting selectively and non-covalently with the type 2 fibroblast growth factor receptor (FGFR2)."^^xsd:string) AnnotationAssertion(rdfs:label "type 2 fibroblast growth factor receptor binding"^^xsd:string) AnnotationAssertion( "FGFR2 ligand"^^xsd:string) AnnotationAssertion( "heartless binding"^^xsd:string) AnnotationAssertion( "heartless ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Notch ligand"^^xsd:string) AnnotationAssertion( "N ligand"^^xsd:string) AnnotationAssertion(rdfs:label "Notch binding"^^xsd:string) AnnotationAssertion( "Notch receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) "Interacting selectively and non-covalently with the Notch (N) protein, a surface receptor."^^xsd:string) AnnotationAssertion( "N binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "PMID:11731473"^^xsd:string) "Interacting selectively and non-covalently with the patched (ptc) protein, a receptor for hedgehog proteins."^^xsd:string) AnnotationAssertion( "ptc binding"^^xsd:string) AnnotationAssertion( "patched ligand"^^xsd:string) AnnotationAssertion( "ptc ligand"^^xsd:string) AnnotationAssertion(rdfs:label "patched binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "transforming growth factor beta ligand binding to type II receptor"^^xsd:string) AnnotationAssertion( "type II TGF-beta binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:11252892"^^xsd:string) "Interacting selectively and non-covalently with a type II transforming growth factor beta receptor."^^xsd:string) AnnotationAssertion( "TGF-beta type II binding"^^xsd:string) AnnotationAssertion( "punt ligand"^^xsd:string) AnnotationAssertion( "transforming growth factor beta receptor type II binding"^^xsd:string) AnnotationAssertion( "punt binding"^^xsd:string) AnnotationAssertion(rdfs:label "type II transforming growth factor beta receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Ror binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with the receptor tyrosine kinase-like orphan receptor (Ror)."^^xsd:string) AnnotationAssertion( "Ror ligand"^^xsd:string) AnnotationAssertion( "receptor tyrosine kinase-like orphan receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "receptor tyrosine kinase-like orphan receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "SE20 receptor binding"^^xsd:string) AnnotationAssertion( "Wit binding"^^xsd:string) AnnotationAssertion(rdfs:label "wishful thinking binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "PMID:11856529"^^xsd:string) "Interacting selectively and non-covalently with wishful thinking (Wit), a type II bone morphogenic protein receptor."^^xsd:string) AnnotationAssertion( "Wit ligand"^^xsd:string) AnnotationAssertion( "wishful thinking ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sev ligand"^^xsd:string) AnnotationAssertion( "sev binding"^^xsd:string) AnnotationAssertion( "sevenless ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "PMID:3151175"^^xsd:string) "Interacting selectively and non-covalently with the sevenless (sev) protein, a receptor tyrosine kinase."^^xsd:string) AnnotationAssertion(rdfs:label "sevenless binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "smo binding"^^xsd:string) AnnotationAssertion( "smo ligand"^^xsd:string) AnnotationAssertion( "smoothened ligand"^^xsd:string) AnnotationAssertion(rdfs:label "smoothened binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "PMID:11731473"^^xsd:string) "Interacting selectively and non-covalently with the smoothened (smo) protein, which interacts with patched to transmit hedgehog signals."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Tl binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) "Interacting selectively and non-covalently with the Toll protein, a transmembrane receptor."^^xsd:string) AnnotationAssertion( "Toll receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "Toll binding"^^xsd:string) AnnotationAssertion( "Toll ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "torso ligand"^^xsd:string) AnnotationAssertion( "tor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "PMID:2927509"^^xsd:string) "Interacting selectively and non-covalently with the torso (tor) protein, a receptor tyrosine kinase."^^xsd:string) AnnotationAssertion( "tor binding"^^xsd:string) AnnotationAssertion(rdfs:label "torso binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "TRAIL binding"^^xsd:string) AnnotationAssertion( "death receptor adaptor protein activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) Annotation( "PMID:15654015"^^xsd:string) "Interacting selectively and non-covalently with any member of the death receptor (DR) family. The DR family falls within the tumor necrosis factor receptor superfamily and is characterized by a cytoplasmic region of ~80 residues termed the death domain (DD)."^^xsd:string) AnnotationAssertion( "death receptor interacting protein activity"^^xsd:string) AnnotationAssertion( "death receptor-associated factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "NGFR binding"^^xsd:string) AnnotationAssertion( "death receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "death receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "TNFR1 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "EDAR binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "KILLER binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "APO binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "FAS binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "DR binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) "Interacting selectively and non-covalently with scavenger receptors, a family of proteins that are expressed on myeloid cells and are involved in the uptake of effete cellular components and foreign particles."^^xsd:string) AnnotationAssertion(rdfs:label "scavenger receptor binding"^^xsd:string) AnnotationAssertion( "scavenger receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198599471"^^xsd:string) "Functions to control the survival, growth, differentiation and effector function of tissues and cells."^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "autocrine activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "paracrine activity"^^xsd:string) AnnotationAssertion(rdfs:label "cytokine activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cytokine receptor binding"^^xsd:string) AnnotationAssertion( "hematopoietin/interferon-class (D200-domain) cytokine receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "hematopoietin/interferon-class (D200-domain) cytokine receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with a cytokine receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ciliary neurotrophic factor receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the ciliary neurotrophic factor receptor."^^xsd:string) AnnotationAssertion(rdfs:label "ciliary neurotrophic factor receptor binding"^^xsd:string) AnnotationAssertion( "ciliary neurotrophic factor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "erythropoietin receptor binding"^^xsd:string) AnnotationAssertion( "erythropoietin"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the erythropoietin receptor."^^xsd:string) AnnotationAssertion( "erythropoietin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "GM-CSF receptor ligand"^^xsd:string) AnnotationAssertion( "GMC-SF receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the granulocyte macrophage colony-stimulating factor receptor."^^xsd:string) AnnotationAssertion( "granulocyte macrophage colony-stimulating factor receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "GM-CSF receptor binding"^^xsd:string) AnnotationAssertion( "granulocyte macrophage colony-stimulating factor"^^xsd:string) AnnotationAssertion(rdfs:label "granulocyte macrophage colony-stimulating factor receptor binding"^^xsd:string) AnnotationAssertion( "granulocyte macrophage colony stimulating factor receptor binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "GC-SF receptor ligand"^^xsd:string) AnnotationAssertion( "G-CSF receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "granulocyte colony-stimulating factor receptor binding"^^xsd:string) AnnotationAssertion( "granulocyte colony-stimulating factor receptor ligand"^^xsd:string) AnnotationAssertion( "granulocyte colony-stimulating factor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the granulocyte colony-stimulating factor receptor."^^xsd:string) AnnotationAssertion( "granulocyte colony stimulating factor receptor binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the growth hormone receptor."^^xsd:string) AnnotationAssertion( "growth hormone receptor ligand"^^xsd:string) AnnotationAssertion( "growth hormone"^^xsd:string) AnnotationAssertion(rdfs:label "growth hormone receptor binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PR:000008922"^^xsd:string) "IFNAR1 binding"^^xsd:string) AnnotationAssertion(Annotation( "PR:000008923"^^xsd:string) "IFNAR2 binding"^^xsd:string) AnnotationAssertion( "interferon-alpha/beta"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17502368"^^xsd:string) "IFNAR binding"^^xsd:string) AnnotationAssertion( "interferon-alpha/beta receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "PR:000008922"^^xsd:string) Annotation( "PR:000008923"^^xsd:string) "interferon-alpha/beta receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:17502368"^^xsd:string) "Interacting selectively and non-covalently with an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2)."^^xsd:string) AnnotationAssertion(rdfs:label "type I interferon receptor binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the interferon-gamma receptor."^^xsd:string) AnnotationAssertion(rdfs:label "interferon-gamma receptor binding"^^xsd:string) AnnotationAssertion( "interferon-gamma"^^xsd:string) AnnotationAssertion( "interferon-gamma receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-2"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-2 receptor."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-2 receptor binding"^^xsd:string) AnnotationAssertion( "interleukin-2 receptor ligand"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-3 receptor."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-3 receptor binding"^^xsd:string) AnnotationAssertion( "IL-3"^^xsd:string) AnnotationAssertion( "interleukin-3 receptor ligand"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-4"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-4 receptor."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-4 receptor binding"^^xsd:string) AnnotationAssertion( "interleukin-4 receptor ligand"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-5"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-5 receptor binding"^^xsd:string) AnnotationAssertion( "interleukin-5 receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-5 receptor."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-6"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-6 receptor."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-6 receptor binding"^^xsd:string) AnnotationAssertion( "interleukin-6 receptor ligand"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-7"^^xsd:string) AnnotationAssertion( "interleukin-7 receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-7 receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-7 receptor."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-9 receptor binding"^^xsd:string) AnnotationAssertion( "interleukin-9 receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-9 receptor."^^xsd:string) AnnotationAssertion( "IL-9"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-10 receptor binding"^^xsd:string) AnnotationAssertion( "interleukin-10 receptor ligand"^^xsd:string) AnnotationAssertion( "IL-10"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-10 receptor."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-11 receptor binding"^^xsd:string) AnnotationAssertion( "interleukin-11 receptor ligand"^^xsd:string) AnnotationAssertion( "IL-11"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-11 receptor."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "interleukin-12 receptor ligand"^^xsd:string) AnnotationAssertion( "IL-12"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-12 receptor."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-12 receptor binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-13 receptor binding"^^xsd:string) AnnotationAssertion( "IL-13"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-13 receptor."^^xsd:string) AnnotationAssertion( "interleukin-13 receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-14 receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-14 receptor."^^xsd:string) AnnotationAssertion( "interleukin-14 receptor ligand"^^xsd:string) AnnotationAssertion( "IL-14"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "leukemia inhibitory factor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the leukemia inhibitory factor receptor."^^xsd:string) AnnotationAssertion(rdfs:label "leukemia inhibitory factor receptor binding"^^xsd:string) AnnotationAssertion( "leukemia inhibitory factor receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "oncostatin-M receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the oncostatin-M receptor."^^xsd:string) AnnotationAssertion(rdfs:label "oncostatin-M receptor binding"^^xsd:string) AnnotationAssertion( "oncostatin-M"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the prolactin receptor."^^xsd:string) AnnotationAssertion( "prolactin"^^xsd:string) AnnotationAssertion( "prolactin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "prolactin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-1 receptor binding"^^xsd:string) AnnotationAssertion( "IL-1"^^xsd:string) AnnotationAssertion( "interleukin-1 receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-1 receptor."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-1 type I"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a Type I interleukin-1 receptor."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-1, Type I receptor binding"^^xsd:string) AnnotationAssertion( "interleukin-1, Type I receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-1 type II"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-1, Type II receptor binding"^^xsd:string) AnnotationAssertion( "interleukin-1, Type II receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a Type II interleukin-1 receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ebc"^^xsd:string) "Blocks the binding of interleukin-1 to the interleukin-1 receptor complex."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-1 receptor antagonist activity"^^xsd:string) AnnotationAssertion( "IL-1ra"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-8"^^xsd:string) AnnotationAssertion( "interleukin-8 receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-8 receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-8 receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "epidermal growth factor receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "epidermal growth factor receptor binding"^^xsd:string) AnnotationAssertion( "transforming growth factor alpha receptor ligand"^^xsd:string) AnnotationAssertion( "EGF receptor ligand"^^xsd:string) AnnotationAssertion( "TGF-alpha receptor binding"^^xsd:string) AnnotationAssertion( "transforming growth factor alpha receptor binding"^^xsd:string) AnnotationAssertion( "EGFR binding"^^xsd:string) AnnotationAssertion( "EGF"^^xsd:string) AnnotationAssertion( "transforming growth factor alpha"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the epidermal growth factor receptor."^^xsd:string) AnnotationAssertion( "TGFalpha receptor binding"^^xsd:string) AnnotationAssertion( "EGF receptor binding"^^xsd:string) AnnotationAssertion( "epidermal growth factor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "macrophage colony stimulating factor receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the macrophage colony-stimulating factor receptor."^^xsd:string) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "M-CSF receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "macrophage colony-stimulating factor receptor binding"^^xsd:string) AnnotationAssertion( "macrophage colony-stimulating factor receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "insulin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the insulin receptor."^^xsd:string) AnnotationAssertion( "insulin receptor ligand"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "insulin-like growth factor"^^xsd:string) AnnotationAssertion( "IGF receptor binding"^^xsd:string) AnnotationAssertion( "insulin-like growth factor receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "insulin-like growth factor receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the insulin-like growth factor receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "transforming growth factor beta receptor binding"^^xsd:string) AnnotationAssertion( "transforming growth factor beta"^^xsd:string) AnnotationAssertion( "TGFbeta receptor binding"^^xsd:string) AnnotationAssertion( "inhibin"^^xsd:string) AnnotationAssertion( "transforming growth factor beta ligand binding to type II receptor"^^xsd:string) AnnotationAssertion( "transforming growth factor beta receptor anchoring activity"^^xsd:string) AnnotationAssertion( "TGF-beta receptor binding"^^xsd:string) AnnotationAssertion( "activin"^^xsd:string) AnnotationAssertion( "transforming growth factor beta ligand binding to type I receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the transforming growth factor beta receptor."^^xsd:string) AnnotationAssertion( "transforming growth factor beta receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "PDGFR binding"^^xsd:string) AnnotationAssertion( "PDGF receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "platelet-derived growth factor receptor binding"^^xsd:string) AnnotationAssertion( "PDGF"^^xsd:string) AnnotationAssertion( "platelet-derived growth factor"^^xsd:string) AnnotationAssertion( "platelet-derived growth factor receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the platelet-derived growth factor receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "neurotrophin"^^xsd:string) AnnotationAssertion( "NGF receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "nerve growth factor receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:15654015"^^xsd:string) "Interacting selectively and non-covalently with the nerve growth factor receptor."^^xsd:string) AnnotationAssertion( "nerve growth factor receptor ligand"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the tumor necrosis factor receptor."^^xsd:string) AnnotationAssertion( "tumor necrosis factor"^^xsd:string) AnnotationAssertion( "TNF receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "tumor necrosis factor receptor binding"^^xsd:string) AnnotationAssertion( "tumor necrosis factor receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a neurotrophin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "neurotrophin receptor binding"^^xsd:string) AnnotationAssertion( "neurotrophin"^^xsd:string) AnnotationAssertion( "neurotrophin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "neurotrophin p75 receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the neurotrophin p75 receptor."^^xsd:string) AnnotationAssertion(rdfs:label "neurotrophin p75 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "neurotrophin TRK receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "neurotrophin TRK receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a neurotrophin TRK receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "neurotrophin TRKA receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "neurotrophin TRKA receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the neurotrophin TRKA receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "neurotrophin TRKB receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the neurotrophin TRKB receptor."^^xsd:string) AnnotationAssertion(rdfs:label "neurotrophin TRKB receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "neurotrophin TRKC receptor binding"^^xsd:string) AnnotationAssertion( "neurotrophin TRKC receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the neurotrophin TRKC receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "hepatocyte growth factor receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the hepatocyte growth factor receptor."^^xsd:string) AnnotationAssertion( "hepatocyte growth factor"^^xsd:string) AnnotationAssertion( "HGF receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "hepatocyte growth factor receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "vascular endothelial growth factor receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with any vascular endothelial growth factor receptor."^^xsd:string) AnnotationAssertion(rdfs:label "vascular endothelial growth factor receptor binding"^^xsd:string) AnnotationAssertion( "vascular endothelial growth factor"^^xsd:string) AnnotationAssertion( "VEGFR binding"^^xsd:string) AnnotationAssertion( "VEGF receptor binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "stem cell factor receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "stem cell factor receptor binding"^^xsd:string) AnnotationAssertion( "SCF"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:10698217"^^xsd:string) "Interacting selectively and non-covalently with the stem cell factor receptor (SCFR), a type III transmembrane kinase receptor."^^xsd:string) AnnotationAssertion( "SCFR binding"^^xsd:string) AnnotationAssertion( "KIT binding"^^xsd:string) AnnotationAssertion( "stem cell factor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0120781859"^^xsd:string) "Interacting selectively and non-covalently with CD40, a receptor found on the surface of all B-lymphocytes."^^xsd:string) AnnotationAssertion(rdfs:label "CD40 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CD27 receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0120781859"^^xsd:string) "Interacting selectively and non-covalently with a CD27, a receptor found on the surface of T cells and some B cells and NK cells."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Neu receptor binding"^^xsd:string) AnnotationAssertion( "Neu receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "ErbB-2 class receptor binding"^^xsd:string) AnnotationAssertion( "HER2 receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the protein-tyrosine kinase receptor Neu/ErbB-2/HER2."^^xsd:string) AnnotationAssertion( "HER2 receptor binding"^^xsd:string) AnnotationAssertion( "ErbB-2 class receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) "Interacting selectively and non-covalently with an integrin."^^xsd:string) AnnotationAssertion(rdfs:label "integrin binding"^^xsd:string) AnnotationAssertion( "integrin ligand"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "peptide hormone"^^xsd:string) AnnotationAssertion( "cAMP generating peptide activity"^^xsd:string) AnnotationAssertion( "lipopeptide hormone"^^xsd:string) AnnotationAssertion(rdfs:label "hormone activity"^^xsd:string) AnnotationAssertion( "glycopeptide hormone"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "gonadotropin hormone-releasing hormone activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "luteinizing hormone/follicle-stimulating hormone releasing factor activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "LH/FSH-RF"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "luteinizing hormone-releasing hormone activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "luteinizing hormone-releasing factor activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "LHRH activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "GnRH activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "PMID:11026571"^^xsd:string) Annotation( "Wikipedia:Gonadotropin-releasing_hormone"^^xsd:string) "The action characteristic of gonadotropin hormone-releasing hormone (GnRH), any of a family of decapeptide amide hormones that are released by the hypothalamus in response to neural and/or chemical stimuli. In at least mammals, upon receptor binding, GnRH causes the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by the anterior pituitary."^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "gonadotrophin hormone-releasing hormone activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "neuropeptide hormone activity"^^xsd:string) AnnotationAssertion( "neurohormone"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "The action characteristic of a neuropeptide hormone, any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue, composed of short chains of amino acids; they include endorphins, enkephalins, vasopressin, and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters, although some are also hormones."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "neurohypophyseal hormone activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "neurohypophysial hormone activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19243634"^^xsd:string) "The action characteristic of a neurohypophyseal hormone, any of a family of structurally and functionally related nonapeptides that are synthesized as part of a larger precursor molecule comprising a signal peptide, the nonapeptide hormone, and a neurophysin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sgd_curators"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "The activity of binding to and activating specific cell surface receptors, thereby inducing behavioral, developmental, or physiological response(s) from a responding organism or cell. The substance may be released or retained on the cell surface. Pheromones may serve as a specific attractant, social communicator, or sexual stimulant."^^xsd:string) AnnotationAssertion(rdfs:label "pheromone activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell."^^xsd:string) AnnotationAssertion(rdfs:label "structural molecule"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "structural constituent of cell wall"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "The action of a molecule that contributes to the structural integrity of a cell wall."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "structural constituent of cytoskeleton"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "The action of a molecule that contributes to the structural integrity of a cytoskeletal structure."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "The action of a molecule that contributes to the structural integrity of the extracellular matrix."^^xsd:string) AnnotationAssertion(rdfs:label "extracellular matrix structural constituent"^^xsd:string) AnnotationAssertion( "extracellular matrix glycoprotein"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "structural constituent of eye lens"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "The action of a molecule that contributes to the structural integrity of the lens of an eye."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "structural protein of chorion"^^xsd:string) AnnotationAssertion(rdfs:label "structural constituent of chorion"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:sensu"^^xsd:string) "The action of a molecule that contributes to the structural integrity of a chorion. An example of this is found in Drosophila melanogaster."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "structural constituent of chitin-based cuticle"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mtg_sensu"^^xsd:string) "The action of a molecule that contributes to the structural integrity of a chitin-based cuticle. An example of this is found in Drosophila melanogaster."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "small-molecule carrier or transporter"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:dgf"^^xsd:string) "Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion(rdfs:label "transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:cy"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism."^^xsd:string) AnnotationAssertion(rdfs:label "ion channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion(rdfs:label "intracellular ligand-gated ion channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "intracellular ligand-gated calcium channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ryanodine receptor"^^xsd:string) AnnotationAssertion( "caffeine-sensitive calcium-release channel"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion(rdfs:label "ryanodine-sensitive calcium-release channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "inositol-1,4,5-trisphosphate receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "InsP3 receptor"^^xsd:string) AnnotationAssertion(rdfs:label "inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity"^^xsd:string) AnnotationAssertion( "IP3 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:8660280"^^xsd:string) Annotation( "Wikipedia:Inositol_trisphosphate_receptor"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a channel that opens when inositol 1,4,5-trisphosphate (IP3) has been bound by the channel complex or one of its constituent parts."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "intracellular cyclic nucleotide activated cation channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transmembrane transfer of a cation by a channel that opens when intracellular cyclic nucleotide has been bound by the channel complex or one of its constituent parts."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "HCN channel activity"^^xsd:string) AnnotationAssertion( "intracellular cyclic AMP activated cation channel activity"^^xsd:string) AnnotationAssertion( "intracellular 3',5' cAMP activated cation channel activity"^^xsd:string) AnnotationAssertion(rdfs:label "intracellular cAMP activated cation channel activity"^^xsd:string) AnnotationAssertion( "intracellular 3',5'-cAMP activated cation channel activity"^^xsd:string) AnnotationAssertion( "intracellular adenosine 3',5'-cyclophosphate activated cation channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "hyperpolarization-activated cyclic nucleotide-gated channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "intracellular cGMP activated cation channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transmembrane transfer of a cation by a channel that opens when intracellular cGMP has been bound by the channel complex or one of its constituent parts."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion(rdfs:label "ATP-binding and phosphorylation-dependent chloride channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Catalysis of the transmembrane transfer of an anion by a volume-sensitive channel. An anion is a negatively charged ion. A volume-sensitive channel is a channel that responds to changes in the volume of a cell."^^xsd:string) AnnotationAssertion(rdfs:label "volume-sensitive anion channel activity"^^xsd:string) AnnotationAssertion( "volume-regulated channel"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcium activated cation channel activity"^^xsd:string) AnnotationAssertion( "intracellular calcium-activated potassium channel"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient."^^xsd:string) AnnotationAssertion( "polycystin"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "intracellular sodium activated potassium channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "PMID:12628167"^^xsd:string) "Catalysis of the transmembrane transfer of potassium by a channel that opens in response to stimulus by a sodium ion or ions. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Sodium activated potassium channels have distinctive properties, including a large single channel conductance, subconductance states, and a block of single channel currents at positive potentials, similar to inward rectification."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transmembrane transfer of chloride by a channel that opens in response to stimulus by a calcium ion or ions. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism."^^xsd:string) AnnotationAssertion(rdfs:label "intracellular calcium activated chloride channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "extracellular ligand-gated ion channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "excitatory extracellular ligand-gated ion channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0323037070"^^xsd:string) "Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific extracellular excitatory ligand has been bound by the channel complex or one of its constituent parts. Excitatory ligands, such as acetylcholine or glutamate, open cation-selective channels."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transmembrane transfer of a cation by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts, and that is activated by serotonin."^^xsd:string) AnnotationAssertion( "5-hydroxytryptamine-gated receptor-channel"^^xsd:string) AnnotationAssertion(rdfs:label "serotonin-activated cation-selective channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "extracellular-glutamate-gated ion channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inhibitory extracellular ligand-gated ion channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0323037070"^^xsd:string) "Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific extracellular inhibitory ligand has been bound by the channel complex or one of its constituent parts. Inhibitory ligands, such as GABA or glycine, open chloride-selective channels."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:14977398"^^xsd:string) "Catalysis of the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself."^^xsd:string) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) "Kir channel activity"^^xsd:string) AnnotationAssertion(rdfs:label "inward rectifier potassium channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "connexin"^^xsd:string) AnnotationAssertion( "intercellular channel"^^xsd:string) AnnotationAssertion( "innexin channel activity"^^xsd:string) AnnotationAssertion( "innexin"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dgh"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes."^^xsd:string) AnnotationAssertion(rdfs:label "gap junction channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "voltage gated ion channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion(rdfs:label "voltage-gated ion channel activity"^^xsd:string) AnnotationAssertion( "voltage-dependent ion channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "voltage-dependent calcium channel activity"^^xsd:string) AnnotationAssertion( "voltage-sensitive calcium channel"^^xsd:string) AnnotationAssertion( "depolarization-activated calcium channel"^^xsd:string) AnnotationAssertion( "depolarization-activated voltage gated calcium channel activity"^^xsd:string) AnnotationAssertion( "depolarization-activated voltage-gated calcium channel"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion(rdfs:label "voltage-gated calcium channel activity"^^xsd:string) AnnotationAssertion( "dihydropyridine-sensitive calcium channel activity"^^xsd:string) AnnotationAssertion( "depolarization-activated voltage-gated calcium channel activity"^^xsd:string) AnnotationAssertion( "voltage gated calcium channel activity"^^xsd:string) AnnotationAssertion( "voltage-gated calcium ion channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Modulates the activity of a calcium channel."^^xsd:string) AnnotationAssertion(rdfs:label "calcium channel regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "voltage-dependent chloride channel activity"^^xsd:string) AnnotationAssertion(rdfs:label "voltage-gated chloride channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion( "voltage gated chloride channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion( "voltage-sensitive sodium channel"^^xsd:string) AnnotationAssertion( "voltage gated sodium channel activity"^^xsd:string) AnnotationAssertion(rdfs:label "voltage-gated sodium channel activity"^^xsd:string) AnnotationAssertion( "voltage-gated sodium ion channel activity"^^xsd:string) AnnotationAssertion( "voltage-dependent sodium channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "voltage-dependent potassium channel activity"^^xsd:string) AnnotationAssertion( "voltage gated potassium channel activity"^^xsd:string) AnnotationAssertion( "voltage-gated potassium ion channel activity"^^xsd:string) AnnotationAssertion(rdfs:label "voltage-gated potassium channel activity"^^xsd:string) AnnotationAssertion( "voltage-sensitive potassium channel"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "A-type (transient outward) potassium channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:5575340"^^xsd:string) "Catalysis of the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel that produces a transient outward current upon a step change in membrane potential."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "delayed rectifier potassium channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:11343411"^^xsd:string) Annotation( "PMID:2462513"^^xsd:string) "Catalysis of the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and activation is slow."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "open rectifier potassium channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:8917578"^^xsd:string) "Catalysis of the transmembrane transfer of a potassium ion by an open rectifier voltage-gated channel. An open rectifier current-voltage relationship is one in which the direction of rectification depends on the external potassium ion concentration."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "anion channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the energy-independent passage of anions across a lipid bilayer down a concentration gradient."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism."^^xsd:string) AnnotationAssertion(rdfs:label "chloride channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cystic fibrosis transmembrane conductance regulator"^^xsd:string) AnnotationAssertion(rdfs:label "channel-conductance-controlling ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.49"^^xsd:string) "cystic-fibrosis membrane-conductance-regulating protein activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.49"^^xsd:string) "ATP phosphohydrolase (channel-conductance-controlling)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.49"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate. An animal enzyme that is active in forming a chloride channel, the absence of which brings about cystic fibrosis. It is also involved in the functioning of other transmembrane channels."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:def"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the energy-independent passage of cations across a lipid bilayer down a concentration gradient."^^xsd:string) AnnotationAssertion( "cation diffusion facilitator activity"^^xsd:string) AnnotationAssertion(rdfs:label "cation channel activity"^^xsd:string) AnnotationAssertion( "nonselective cation channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism."^^xsd:string) AnnotationAssertion(rdfs:label "calcium channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "potassium channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism."^^xsd:string) AnnotationAssertion(rdfs:label "sodium channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "allantoin uptake transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "allantoin/allantoate transporter"^^xsd:string) AnnotationAssertion( "allantoin permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:2.A.39.3.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: allantoin(out) + H+(out) = allantoin(in) + H+(in) by secondary active transport."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of amines, including polyamines, from one side of the membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group."^^xsd:string) AnnotationAssertion(rdfs:label "amine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "amine/amide/polyamine channel activity"^^xsd:string) AnnotationAssertion( "amine/polyamine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "amino acid-polyamine transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "hydrogen:vesicular amine antiporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "vesicular hydrogen:amino acid antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "Reactome:428625"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a vesicle membrane to the other according to the reaction: H+(in) + amino acid(out) = H+(out) + amino acid(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of acetylcholine from one side of the membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions."^^xsd:string) AnnotationAssertion(rdfs:label "acetylcholine transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.1.2.13"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acetylcholine(in) = H+(in) + acetylcholine(out)."^^xsd:string) AnnotationAssertion( "acetylcholine:proton antiporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetylcholine:hydrogen antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + H+(out) = amino acid(in) + H+(in)."^^xsd:string) AnnotationAssertion( "cation/amino acid symporter"^^xsd:string) AnnotationAssertion(rdfs:label "hydrogen:amino acid symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "insulin-activated sodium:amino acid symporter activity"^^xsd:string) AnnotationAssertion( "glutamate/aspartate:sodium symporter activity"^^xsd:string) AnnotationAssertion( "sodium:amino acid transporter activity"^^xsd:string) AnnotationAssertion( "sodium/amino acid transporter activity"^^xsd:string) AnnotationAssertion( "insulin-activated sodium:amino acid transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "sodium:amino acid symporter activity"^^xsd:string) AnnotationAssertion( "insulin-activated sodium/amino acid transporter activity"^^xsd:string) AnnotationAssertion( "sodium/excitatory amino acid symporter activity"^^xsd:string) AnnotationAssertion( "isoleucine/valine:sodium symporter activity"^^xsd:string) AnnotationAssertion( "sodium/excitatory amino acid cotransporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + Na+(out) = amino acid(in) + Na+(in)."^^xsd:string) AnnotationAssertion( "threonine/serine:sodium symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "high affinity basic amino acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of basic amino acids from one side of a membrane to the other. Acidic amino acids have a pH above 7. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations."^^xsd:string) AnnotationAssertion( "high-affinity basic amino acid transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of arginine from one side of a membrane to the other. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations."^^xsd:string) AnnotationAssertion(rdfs:label "high affinity arginine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "high-affinity arginine transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "histidine/arginine/lysine/ornithine porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-histidine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "L-histidine transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "high affinity L-histidine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "high affinity histidine permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "high affinity lysine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of lysine from one side of a membrane to the other. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations."^^xsd:string) AnnotationAssertion( "high affinity lysine transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of a neutral L-amino acid from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport."^^xsd:string) AnnotationAssertion(rdfs:label "neutral L-amino acid secondary active transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "neutral L-amino acid porter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "neutral amino acid:sodium symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.23.3.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral amino acid(out) + Na+(out) = neutral amino acid(in) + Na+(in)."^^xsd:string) AnnotationAssertion( "neutral amino acid-sodium cotransporter"^^xsd:string) AnnotationAssertion( "sodium/neutral amino acid transporter"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + H+(out) = proline(in) + H+(in)."^^xsd:string) AnnotationAssertion( "hydrogen/proline transporter"^^xsd:string) AnnotationAssertion(rdfs:label "hydrogen:proline symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sodium/proline symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "proline:sodium symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.22.2.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + Na+(out) = proline(in) + Na+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "high-affinity tryptophan transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "high-affinity tryptophan transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the high-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "valine/tyrosine/tryptophan permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-tyrosine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-tyrosine from one side of a membrane to the other. L-tyrosine is 2-amino-3-(4-hydroxyphenyl)propanoic acid."^^xsd:string) AnnotationAssertion( "L-tyrosine permease activity"^^xsd:string) AnnotationAssertion( "L-tyrosine transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "leucine/isoleucine/valine porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-valine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-valine from one side of a membrane to the other. L-valine is 2-amino-3-methylbutanoic acid."^^xsd:string) AnnotationAssertion( "isoleucine/valine:sodium symporter activity"^^xsd:string) AnnotationAssertion( "L-valine transporter activity"^^xsd:string) AnnotationAssertion( "valine/tyrosine/tryptophan permease activity"^^xsd:string) AnnotationAssertion( "leucine/valine/isoleucine permease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "choline:sodium symporter activity"^^xsd:string) AnnotationAssertion( "sodium/choline symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.22.3.5"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: choline(out) + Na+(out) = choline(in) + Na+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "creatine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of creatine across a membrane. Creatine is a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "creatine:sodium symporter activity"^^xsd:string) AnnotationAssertion( "sodium/chloride-dependent creatine transporter"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.22.3.4"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: creatine(out) + Na+(out) = creatine(in) + Na+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of dicarboxylic acids from one side of the membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups."^^xsd:string) AnnotationAssertion( "dicarboxylic acid permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "dicarboxylic acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "dicarboxylate (succinate/fumarate/malate) antiporter activity"^^xsd:string) AnnotationAssertion( "sodium:dicarboxylate/tricarboxylate symporter activity"^^xsd:string) AnnotationAssertion( "dicarboxylate carrier"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glutamate/aspartate porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-glutamate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "glutamate/aspartate:sodium symporter activity"^^xsd:string) AnnotationAssertion( "L-glutamate transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "high-affinity glutamate transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "high-affinity glutamate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.3.10.5"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + H+(out) = glutamate(in) + H+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inorganic phosphate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of a inorganic phosphate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.20.2.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: HPO42-(out) + Na+(out) = HPO42-(in) + Na+(in)."^^xsd:string) AnnotationAssertion( "sodium/phosphate cotransporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "high affinity inorganic phosphate:sodium symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lipid transporter activity"^^xsd:string) AnnotationAssertion( "lipophorin"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of lipids into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion( "apolipoprotein"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "plasma membrane long-chain fatty acid transporter"^^xsd:string) AnnotationAssertion(rdfs:label "long-chain fatty acid transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15904"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of long-chain fatty acids into, out of or within a cell, or between cells. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peroxisomal fatty-acyl-CoA transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "peroxisomal fatty acyl CoA transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.47"^^xsd:string) "ATP phosphohydrolase (fatty-acyl-CoA-transporting)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.47"^^xsd:string) "Catalysis of the reaction: ATP + H2O + fatty acyl CoA(cis) = ADP + phosphate + fatty acyl CoA(trans). The transport of fatty acyl CoA into and out of peroxisomes."^^xsd:string) AnnotationAssertion( "fatty-acyl-CoA-transporting ATPase"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell."^^xsd:string) AnnotationAssertion(rdfs:label "neurotransmitter transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "neurotransmitter transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.22.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neurotransmitter(out) + Na+(out) = neurotransmitter(in) + Na+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "neurotransmitter:sodium symporter activity"^^xsd:string) AnnotationAssertion( "sodium/neurotransmitter symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of dopamine from one side of the membrane to the other. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline."^^xsd:string) AnnotationAssertion(rdfs:label "dopamine transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.22.1.3"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dopamine(out) + Na+(out) = dopamine(in) + Na+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "dopamine:sodium symporter activity"^^xsd:string) AnnotationAssertion( "sodium/dopamine symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.22.3.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + Na+(out) = gamma-aminobutyric acid(in) + Na+(in)."^^xsd:string) AnnotationAssertion( "sodium/chloride-dependent GABA transporter activity"^^xsd:string) AnnotationAssertion( "betaine/GABA:sodium symporter activity"^^xsd:string) AnnotationAssertion( "4-aminobutyrate:sodium symporter activity"^^xsd:string) AnnotationAssertion( "GABA:sodium symporter activity"^^xsd:string) AnnotationAssertion( "4-aminobutanoate:sodium symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "gamma-aminobutyric acid:sodium symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "norepinephrine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "levarterenol transporter activity"^^xsd:string) AnnotationAssertion( "noradrenaline transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of norepinephrine from one side of the membrane to the other. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "noradrenaline:sodium symporter activity"^^xsd:string) AnnotationAssertion( "sodium/norepinephrine symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.22.1.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: norepinephrine(out) + Na+(out) = norepinephrine(in) + Na+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "norepinephrine:sodium symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sodium/serotonin symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.22.1.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: serotonin(out) + Na+(out) = serotonin(in) + Na+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "serotonin:sodium symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide) from one side of a membrane to the other."^^xsd:string) AnnotationAssertion( "intracellular nucleoside transmembrane transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "nucleoside transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "PMID:15034926"^^xsd:string) "Catalysis of the transfer of a nucleotide-sugar from one side of the membrane to the other. A nucleotide-sugar is any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative."^^xsd:string) AnnotationAssertion(rdfs:label "nucleotide-sugar transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nucleotide-sulfate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "nucleotide-sulphate transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of nucleotide-sulfate from one side of a membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "organic acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of organic acids, any acidic compound containing carbon in covalent linkage, from one side of the membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sodium/chloride-dependent organic acid cotransporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.28.1.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organic acid(out) + Na+(out) = organic acid(in) + Na+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "organic acid:sodium symporter activity"^^xsd:string) AnnotationAssertion( "sodium:dicarboxylate/tricarboxylate symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxygen transporter activity"^^xsd:string) AnnotationAssertion( "oxygen-carrying"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of oxygen into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion( "globin"^^xsd:string) AnnotationAssertion( "hemerythrin"^^xsd:string) AnnotationAssertion( "hemocyanin"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "purine base transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "purine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:26386"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "purine nucleobase transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "purine ribonucleotide transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, from one side of a membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "ATP transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:26432"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "pyrimidine base transmembrane transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyrimidine nucleobase transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "pyrimidine transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sugar transporter"^^xsd:string) AnnotationAssertion( "proton:sugar symporter activity"^^xsd:string) AnnotationAssertion( "hydrogen:sugar transporter activity"^^xsd:string) AnnotationAssertion( "cation/sugar symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.1.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + H+(out) = sugar(in) + H+(in)."^^xsd:string) AnnotationAssertion( "sugar:hydrogen ion symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "sugar:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "sugar porter activity"^^xsd:string) AnnotationAssertion( "hydrogen:sugar symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "general alpha-glucoside transporter activity"^^xsd:string) AnnotationAssertion( "general alpha-glucoside:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.1.11"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-glucoside(out) + H+(out) = alpha-glucoside(in) + H+(in). Alpha-glucosides include trehalose, maltose, turanose, isomaltose, alpha-methylglucoside, maltotriose, palatinose, trehalose and melezitose."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-glucoside:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "general alpha-glucoside:proton symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "fructose permease activity"^^xsd:string) AnnotationAssertion( "fructose porter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of fructose from one side of the membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey."^^xsd:string) AnnotationAssertion(rdfs:label "fructose transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "galactose transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "galactose/glucose (methylgalactoside) porter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of galactose from one side of the membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "lactose/glucose efflux transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucose transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of the hexose monosaccharide glucose from one side of the membrane to the other."^^xsd:string) AnnotationAssertion( "glucose permease activity"^^xsd:string) AnnotationAssertion( "galactose/glucose (methylgalactoside) porter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "transepithelial hydrogen:glucose symporter activity"^^xsd:string) AnnotationAssertion( "hydrogen:glucose transporter activity"^^xsd:string) AnnotationAssertion( "transepithelial hydrogen:glucose transporter activity"^^xsd:string) AnnotationAssertion( "transepithelial hydrogen/glucose transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydrogen:glucose symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy."^^xsd:string) AnnotationAssertion( "constitutive hydrogen:glucose transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "constitutive hydrogen:glucose symporter activity"^^xsd:string) AnnotationAssertion( "constitutive hydrogen/glucose transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "high-affinity hydrogen/glucose transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations."^^xsd:string) AnnotationAssertion( "high-affinity hydrogen:glucose transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "high-affinity hydrogen:glucose symporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy."^^xsd:string) AnnotationAssertion( "low-affinity hydrogen:glucose transporter activity"^^xsd:string) AnnotationAssertion( "low-affinity hydrogen/glucose transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "low-affinity hydrogen:glucose symporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "insulin-responsive hydrogen:glucose symporter activity"^^xsd:string) AnnotationAssertion( "transepithelial hydrogen/glucose transporter activity"^^xsd:string) AnnotationAssertion( "insulin-responsive hydrogen:glucose transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+, in response to a stimulus by insulin. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "low-affinity glucose:sodium symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.21.3.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations."^^xsd:string) AnnotationAssertion( "low-affinity glucose-sodium cotransporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "maltose porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "maltose transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of maltose from one side of the membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "maltose:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "hydrogen/maltose transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.1.10"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: maltose(out) + H+(out) = maltose(in) + H+(in)."^^xsd:string) AnnotationAssertion( "maltose permease"^^xsd:string) AnnotationAssertion( "maltose:proton symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "myo-inositol transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "vitamin Bh transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of myo-inositol from one side of the membrane to the other. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "myo-inositol:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "myo-inositol:proton symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.1.8"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + H+(out) = myo-inositol(in) + H+(in)."^^xsd:string) AnnotationAssertion( "hydrogen/myo-inositol transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "myo-inositol:sodium symporter activity"^^xsd:string) AnnotationAssertion( "myo-inositol-sodium cotransporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.21.4.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + Na+(out) = myo-inositol(in) + Na+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of taurine from one side of the membrane to the other. Taurine (2-aminoethanesulfonic acid) is a sulphur-containing amino acid derivative which is important in the metabolism of fats."^^xsd:string) AnnotationAssertion(rdfs:label "taurine transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sodium/chloride-dependent taurine transporter"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.22.3.3"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: taurine(out) + Na+(out) = taurine(in) + Na+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "taurine:sodium symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tricarboxylate secondary active transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "tricarboxylate carrier activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of tricarboxylate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "water transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of water (H2O) from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of copper (Cu) ions from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "copper ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "intracellular copper ion transporter"^^xsd:string) AnnotationAssertion( "plasma membrane copper transporter"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "zinc, iron permease activity"^^xsd:string) AnnotationAssertion( "transmembrane iron permease activity"^^xsd:string) AnnotationAssertion( "transmembrane iron ion permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "iron ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "multicopper ferroxidase iron transport mediator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of iron (Fe) ions from one side of a membrane to the other."^^xsd:string) AnnotationAssertion( "iron transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "manganese ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dgf"^^xsd:string) "Catalysis of the transfer of manganese (Mn) ions from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity"^^xsd:string) AnnotationAssertion( "zinc, cadmium uptake permease activity"^^xsd:string) AnnotationAssertion( "zinc, iron permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dgf"^^xsd:string) "Catalysis of the transfer of zinc (Zn) ions from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "zinc ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "cobalt, zinc uptake permease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.8"^^xsd:string) "calcium-translocating P-type ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.8"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans)."^^xsd:string) AnnotationAssertion( "calcium ABC transporter"^^xsd:string) AnnotationAssertion( "calcium efflux ATPase"^^xsd:string) AnnotationAssertion(rdfs:label "calcium-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "calcium transporting ATPase activity"^^xsd:string) AnnotationAssertion( "calcium pump"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.8"^^xsd:string) "plasma membrane Ca-ATPase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.8"^^xsd:string) "ATP phosphohydrolase (Ca2+-transporting)"^^xsd:string) AnnotationAssertion( "sarcoplasmic reticulum ATPase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.8"^^xsd:string) "Ca2+-pumping ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.8"^^xsd:string) "Ca(2+)-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.8"^^xsd:string) "Ca2+-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.8"^^xsd:string) "sarco(endo)plasmic reticulum Ca2+-ATPase"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.9"^^xsd:string) "sodium/potassium-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.9"^^xsd:string) "ATP phosphohydrolase (Na+/K+-exchanging)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.9"^^xsd:string) "Na,K-activated ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.9"^^xsd:string) "Na,K-pump"^^xsd:string) AnnotationAssertion( "sodium/potassium-exchanging ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.9"^^xsd:string) "(Na+ + K+)-activated ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.9"^^xsd:string) "Na(+)/K(+)-exchanging ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.9"^^xsd:string) "(Na+ + K+)-ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.9"^^xsd:string) "Na+,K+ pump"^^xsd:string) AnnotationAssertion( "sodium pump"^^xsd:string) AnnotationAssertion(rdfs:label "sodium:potassium-exchanging ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.9"^^xsd:string) "Na+,K+-ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.9"^^xsd:string) "Na+/K+-ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.9"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.9"^^xsd:string) "Na(+)/K(+)-ATPase activity"^^xsd:string) AnnotationAssertion( "sodium:potassium exchanging ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.9"^^xsd:string) "Na+/K+-exchanging ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "eye pigment precursor transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:3.A.1.204.1"^^xsd:string) "Catalysis of the reaction: ATP + H2O + eye pigment precursor(in) = ADP + phosphate + eye pigment precursor(out)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + cation(out) = sugar(in) + cation(in)."^^xsd:string) AnnotationAssertion(rdfs:label "cation:sugar symporter activity"^^xsd:string) AnnotationAssertion( "sugar:cation symporter activity"^^xsd:string) AnnotationAssertion( "cation/sugar symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.21.3.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "glucose:sodium symporter activity"^^xsd:string) AnnotationAssertion( "sodium/glucose symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sodium-dependent nucleoside transporter activity"^^xsd:string) AnnotationAssertion( "nucleoside-sodium cotransporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + Na+(out) = nucleoside(in) + Na+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "nucleoside:sodium symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + cation(out) = amino acid(in) + cation(in)."^^xsd:string) AnnotationAssertion(rdfs:label "cation:amino acid symporter activity"^^xsd:string) AnnotationAssertion( "cation/amino acid symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "OMIM:600544"^^xsd:string) "Catalysis of the transfer of a oligopeptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement."^^xsd:string) AnnotationAssertion( "hydrogen/oligopeptide symporter"^^xsd:string) AnnotationAssertion( "proton-dependent oligopeptide transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "proton-dependent oligopeptide secondary active transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of amines across chromaffin granule membranes."^^xsd:string) AnnotationAssertion(rdfs:label "chromaffin granule amine transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of amines across synaptic vesicle membranes."^^xsd:string) AnnotationAssertion(rdfs:label "synaptic vesicle amine transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) Annotation( "PMID:16371597"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in)."^^xsd:string) AnnotationAssertion( "mitochondrial sodium/calcium ion exchange"^^xsd:string) AnnotationAssertion( "sodium/calcium exchanger"^^xsd:string) AnnotationAssertion( "sodium:calcium exchange"^^xsd:string) AnnotationAssertion(rdfs:label "calcium:sodium antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sodium/phosphate symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + phosphate(out) = Na+(in) + phosphate(in)."^^xsd:string) AnnotationAssertion(rdfs:label "sodium:phosphate symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent cation(out) + H+(in) = monovalent cation(in) + H+(out)."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "monovalent cation:proton antiporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "monovalent cation:hydrogen antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion A(out) + inorganic anion B(in) = inorganic anion A(in) + inorganic anion B(out)."^^xsd:string) AnnotationAssertion(rdfs:label "inorganic anion exchanger activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CMP-N-acetylneuraminate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a CMP-N-acetylneuraminate from one side of the membrane to the other."^^xsd:string) AnnotationAssertion( "CMP-sialic acid transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a GDP-fucose from one side of the membrane to the other. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "GDP-fucose transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GDP-mannose transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a GDP-mannose from one side of the membrane to the other. GDP-mannose is a substance composed of mannose in glycosidic linkage with guanosine diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a UDP-galactose from one side of the membrane to the other. UDP-galactose is a substance composed of galactose in glycosidic linkage with uridine diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "UDP-galactose transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-glucose transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a UDP-glucose from one side of the membrane to the other. UDP-glucose is a substance composed of glucose in glycosidic linkage with uridine diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-glucuronic acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a UDP-glucuronic acid from one side of the membrane to the other. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-N-acetylglucosamine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a UDP-N-acetylglucosamine from one side of the membrane to the other. N-acetylglucosamine is a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-N-acetylgalactosamine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a N-acetylgalactosamine from one side of the membrane to the other. N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of UDP-xylose from one side of the membrane to the other. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "UDP-xylose transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.29.13.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + fumarate(in) = succinate(in) + fumarate(out)."^^xsd:string) AnnotationAssertion(rdfs:label "succinate:fumarate antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ATP/ADP exchange"^^xsd:string) AnnotationAssertion( "ATP/ADP exchanger"^^xsd:string) AnnotationAssertion( "ADP/ATP translocase"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.29.1.1"^^xsd:string) "Catalysis of the reaction: ATP(out) + ADP(in) = ATP(in) + ADP(out)."^^xsd:string) AnnotationAssertion( "adenine nucleotide translocase"^^xsd:string) AnnotationAssertion(rdfs:label "ATP:ADP antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "flavin-adenine dinucleotide carrier activity"^^xsd:string) AnnotationAssertion(rdfs:label "FAD carrier activity"^^xsd:string) AnnotationAssertion( "flavin adenine dinucleotide carrier activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of flavin adenine dinucleotide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "fatty acyl carnitine carrier"^^xsd:string) AnnotationAssertion(rdfs:label "carnitine:acyl carnitine antiporter activity"^^xsd:string) AnnotationAssertion( "carnitine:acyl carnitine carrier activity"^^xsd:string) AnnotationAssertion( "carnitine/acyl carnitine carrier activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9032458"^^xsd:string) "Catalysis of the reaction: carnitine (mitochondrial) + acyl carnitine (cytoplasm) = carnitine (cytoplasm) + acyl carnitine (mitochondrial)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyruvate secondary active transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of pyruvate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport."^^xsd:string) AnnotationAssertion( "pyruvate carrier activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:14570579"^^xsd:string) Annotation( "PMID:15556857"^^xsd:string) "Interacting selectively and non-covalently with both N-ethylmaleimide-sensitive fusion protein (NSF) and a cis-SNARE complex (i.e. a SNARE complex in which all proteins are associated with the same membrane) and increasing the ATPase activity of NSF, thereby allowing ATP hydrolysis by NSF to disassemble the cis-SNARE complex."^^xsd:string) AnnotationAssertion( "SNAP"^^xsd:string) AnnotationAssertion(rdfs:label "soluble NSF attachment protein activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "SNAP-25"^^xsd:string) AnnotationAssertion( "SNARE"^^xsd:string) AnnotationAssertion( "t-SNARE activity"^^xsd:string) AnnotationAssertion( "Q-SNARE activity"^^xsd:string) AnnotationAssertion( "R-SNARE activity"^^xsd:string) AnnotationAssertion( "v-SNARE activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:14570579"^^xsd:string) "Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion."^^xsd:string) AnnotationAssertion(rdfs:label "SNAP receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nucleocytoplasmic transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of substances between the nucleus and the cytoplasm of a cell."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule."^^xsd:string) AnnotationAssertion(rdfs:label "binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "steroid binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:50113"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with any androgen, male sex hormones."^^xsd:string) AnnotationAssertion(rdfs:label "androgen binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:27300"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0471331309"^^xsd:string) "Interacting selectively and non-covalently with vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3)."^^xsd:string) AnnotationAssertion( "cholecalciferol binding"^^xsd:string) AnnotationAssertion( "calciferol binding"^^xsd:string) AnnotationAssertion( "ergocalciferol binding"^^xsd:string) AnnotationAssertion(rdfs:label "vitamin D binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "juvenile hormone binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with juvenile hormone, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity."^^xsd:string) AnnotationAssertion(rdfs:label "retinoid binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "11-cis retinaldehyde binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:16066"^^xsd:string) "Interacting selectively and non-covalently with 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. Retinal is one of the three compounds that makes up vitamin A."^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:16066"^^xsd:string) "11-cis-retinal binding"^^xsd:string) AnnotationAssertion(rdfs:label "11-cis retinal binding"^^xsd:string) AnnotationAssertion( "vitamin A binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "trans retinal binding"^^xsd:string) AnnotationAssertion(rdfs:label "all-trans retinal binding"^^xsd:string) AnnotationAssertion( "xanthopsin"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:17898"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Interacting selectively and non-covalently with all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A."^^xsd:string) AnnotationAssertion( "visual yellow binding"^^xsd:string) AnnotationAssertion( "all-trans retinaldehyde binding"^^xsd:string) AnnotationAssertion( "vitamin A binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis."^^xsd:string) AnnotationAssertion(rdfs:label "fatty acid binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "iron ion binding"^^xsd:string) AnnotationAssertion( "iron binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with iron (Fe) ions."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "copper/cadmium binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with copper (Cu) ions."^^xsd:string) AnnotationAssertion( "copper binding"^^xsd:string) AnnotationAssertion(rdfs:label "copper ion binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcium ion binding"^^xsd:string) AnnotationAssertion( "calcium ion storage activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with calcium ions (Ca2+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "protein amino acid binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "protein folding chaperone"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules)."^^xsd:string) AnnotationAssertion( "alpha-2 macroglobulin receptor-associated protein activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein binding"^^xsd:string) AnnotationAssertion( "protein degradation tagging activity"^^xsd:string) AnnotationAssertion( "protein tagging activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calmodulin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "collagen binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cytoskeletal regulatory protein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "PMID:15163540"^^xsd:string) "Interacting selectively and non-covalently with any protein involved in modulating the reorganization of the cytoskeleton."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "insulin-like growth factor binding"^^xsd:string) AnnotationAssertion( "IGF binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with an insulin-like growth factor, any member of a group of polypeptides that are structurally homologous to insulin and share many of its biological activities, but are immunologically distinct from it."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope."^^xsd:string) AnnotationAssertion( "lamin/chromatin binding"^^xsd:string) AnnotationAssertion(rdfs:label "lamin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "profilin binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0721662544"^^xsd:string) "Interacting selectively and non-covalently with profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) Annotation( "ISBN:0815316194"^^xsd:string) "Interacting selectively and non-covalently with tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle."^^xsd:string) AnnotationAssertion(rdfs:label "tropomyosin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator."^^xsd:string) AnnotationAssertion(rdfs:label "ATP binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GTP binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with GTP, guanosine triphosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a macrolide, any of a large group of structurally related antibiotics produced by Streptomyces species."^^xsd:string) AnnotationAssertion(rdfs:label "macrolide binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "FK506 binding"^^xsd:string) AnnotationAssertion( "FK506-sensitive peptidyl-prolyl cis-trans isomerase"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the immunosuppressant FK506."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:28260"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with the aldohexose galactose (galacto-hexose), a common constituent of many oligo- and polysaccharides."^^xsd:string) AnnotationAssertion( "galactose binding lectin"^^xsd:string) AnnotationAssertion(rdfs:label "galactose binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucose binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:17234"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the D- or L-enantiomer of glucose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mannose binding"^^xsd:string) AnnotationAssertion( "mannose binding lectin"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:37684"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0192800981"^^xsd:string) "Interacting selectively and non-covalently with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with any glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues."^^xsd:string) AnnotationAssertion(rdfs:label "glycosaminoglycan binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hyaluronic acid binding"^^xsd:string) AnnotationAssertion( "hyaluronan binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:16336"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "vitamin M binding"^^xsd:string) AnnotationAssertion( "vitamin B9 binding"^^xsd:string) AnnotationAssertion(rdfs:label "folic acid binding"^^xsd:string) AnnotationAssertion( "folate binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester."^^xsd:string) AnnotationAssertion(rdfs:label "phospholipid binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium."^^xsd:string) AnnotationAssertion(rdfs:label "calcium-dependent phospholipid binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol."^^xsd:string) AnnotationAssertion(rdfs:label "1-phosphatidylinositol binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ebc"^^xsd:string) "phosphatidylinositol 4,5-bisphosphate binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions."^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:18348"^^xsd:string) "PIP2 binding"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol-4,5-bisphosphate binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "PtdIns(4,5)P2 binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:18348"^^xsd:string) "1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "PIP3 binding"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol-3,4,5-trisphosphate binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester."^^xsd:string) AnnotationAssertion(rdfs:label "phospholipid transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "odorant binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0721662544"^^xsd:string) "Interacting selectively and non-covalently with an odorant, any substance capable of stimulating the sense of smell."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pheromone binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chemokine activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) Annotation( "PMID:12183377"^^xsd:string) Annotation( "http://en.wikipedia.org/wiki/Chemokine"^^xsd:string) Annotation( "http://www.copewithcytokines.de/cope.cgi?key=Cytokines"^^xsd:string) "The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mtg_sensu"^^xsd:string) "The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a larva. An example of this is found in Drosophila melanogaster."^^xsd:string) AnnotationAssertion(rdfs:label "structural constituent of chitin-based larval cuticle"^^xsd:string) AnnotationAssertion( "structural constituent of larval cuticle"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "structural constituent of pupal chitin-based cuticle"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mtg_sensu"^^xsd:string) "The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a pupa. An example of this is found in Drosophila melanogaster."^^xsd:string) AnnotationAssertion( "structural constituent of pupal cuticle"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mtg_sensu"^^xsd:string) "The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of an adult organism. An example of this is found in Drosophila melanogaster."^^xsd:string) AnnotationAssertion(rdfs:label "structural constituent of adult chitin-based cuticle"^^xsd:string) AnnotationAssertion( "structural constituent of adult cuticle"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-catenin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Interacting selectively and non-covalently with the beta subunit of the catenin complex."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "microtubule/chromatin interaction"^^xsd:string) AnnotationAssertion(rdfs:label "microtubule binding"^^xsd:string) AnnotationAssertion( "microtubule severing activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "G-protein-coupled photoreceptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "photoreceptor activity, G-protein coupled"^^xsd:string) AnnotationAssertion( "G protein coupled photoreceptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled photoreceptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jsg"^^xsd:string) Annotation( "GOC:sl"^^xsd:string) "COOH-terminus binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jsg"^^xsd:string) "carboxylate-terminal binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sl"^^xsd:string) "carboxy-terminus binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxy function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue."^^xsd:string) AnnotationAssertion(Annotation( "GOC:jsg"^^xsd:string) "carboxy-terminal binding"^^xsd:string) AnnotationAssertion(rdfs:label "protein C-terminus binding"^^xsd:string) AnnotationAssertion( "C-terminal binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jsg"^^xsd:string) "carboxylate-terminus binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sl"^^xsd:string) "C-terminal end binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jsg"^^xsd:string) "COOH-terminal binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sl"^^xsd:string) "carboxyl-terminus binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jsg"^^xsd:string) "carboxyl-terminal binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix."^^xsd:string) AnnotationAssertion(rdfs:label "ATP-dependent helicase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "monocarboxylate carrier"^^xsd:string) AnnotationAssertion( "prostaglandin/thromboxane transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "monocarboxylic acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of monocarboxylic acids from one side of the membrane to the other. A monocarboxylic acid is an organic acid with one COOH group."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "pentaxin receptor"^^xsd:string) AnnotationAssertion(rdfs:label "pentraxin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with a pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:18840757"^^xsd:string) "Combining with a neuronal pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "neuronal pentraxin receptor activity"^^xsd:string) AnnotationAssertion( "neuronal pentaxin receptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "eclosion hormone activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "The action characteristic of eclosion hormone, a peptide hormone that, upon receptor binding, triggers the death of certain muscles and neurons during insect metamorphosis."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "high-density lipoprotein particle binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with high-density lipoprotein particle, a lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "HDL binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "diuretic hormone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with a diuretic hormone and transmitting the signal to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "axon guidance receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) Annotation( "PMID:15107857"^^xsd:string) Annotation( "PMID:15339666"^^xsd:string) "Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "receptor activity involved in axon guidance"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Increases the activity of an enzyme."^^xsd:string) AnnotationAssertion(rdfs:label "enzyme activator activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcium sensitive guanylate cyclase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Increases the activity of guanylate cyclase in response to a change in calcium ion concentration."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:pg"^^xsd:string) "ARF GAP activity"^^xsd:string) AnnotationAssertion(rdfs:label "ARF GTPase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Increases the rate of GTP hydrolysis by the GTPase ARF."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chitin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "glutamate receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "extracellular-glutamate-gated chloride channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "The stopping, prevention or reduction of the activity of the enzyme ornithine decarboxylase."^^xsd:string) AnnotationAssertion(rdfs:label "ornithine decarboxylase inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "translation termination factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ma"^^xsd:string) "Functions in the termination of translation."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "N-acetyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phosphodiesterase"^^xsd:string) AnnotationAssertion( "inositol or phosphatidylinositol phosphodiesterase activity"^^xsd:string) AnnotationAssertion( "inositol/phosphatidylinositol phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group."^^xsd:string) AnnotationAssertion(rdfs:label "phosphoric diester hydrolase activity"^^xsd:string) AnnotationAssertion( "endonuclease VIII activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0815316194"^^xsd:string) "The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation."^^xsd:string) AnnotationAssertion(rdfs:label "growth factor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "imaginal disc growth factor receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with an imaginal disc growth factor receptor."^^xsd:string) AnnotationAssertion( "imaginal disc growth factor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "light-activated voltage gated calcium channel activity"^^xsd:string) AnnotationAssertion( "light-activated voltage-dependent calcium channel activity"^^xsd:string) AnnotationAssertion(rdfs:label "light-activated voltage-gated calcium channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a voltage-gated channel that is activated in response to light. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton)."^^xsd:string) AnnotationAssertion(rdfs:label "cytoskeletal protein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_MIT_16mar07"^^xsd:string) "The binding activity of a molecule that brings together a cytoskeletal protein and one or more other molecules, permitting them to function in a coordinated way."^^xsd:string) AnnotationAssertion(rdfs:label "cytoskeletal adaptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "DNA dependent ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single- or double-stranded DNA, and it drives another reaction."^^xsd:string) AnnotationAssertion(rdfs:label "DNA-dependent ATPase activity"^^xsd:string) AnnotationAssertion( "DNA-dependent adenosinetriphosphatase activity"^^xsd:string) AnnotationAssertion( "adenosinetriphosphatase (DNA-dependent)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:8396141"^^xsd:string) "Catalysis of the hydrolysis of the epoxide in a juvenile hormone to the corresponding diol."^^xsd:string) AnnotationAssertion(rdfs:label "juvenile hormone epoxide hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0321000382"^^xsd:string) "Interacting selectively and non-covalently with 5S ribosomal RNA, the smallest RNA constituent of a ribosome."^^xsd:string) AnnotationAssertion(rdfs:label "5S rRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the unprocessed 5S ribosomal RNA transcript."^^xsd:string) AnnotationAssertion(rdfs:label "5S rRNA primary transcript binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alcohol dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion( "NADP-aldehyde reductase activity"^^xsd:string) AnnotationAssertion( "alcohol:NADP dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.2"^^xsd:string) "aldehyde reductase (NADPH) activity"^^xsd:string) AnnotationAssertion( "aldehyde reductase (NADPH2) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.2"^^xsd:string) "Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "guanosine diphospho-L-fucose-lactose fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "blood group H alpha-2-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "guanosine diphosphofucose-lactose fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "alpha-2-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "galactoside 2-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "GDP-L-fucose:lactose fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-R = GDP + alpha-L-fucosyl-(1,2)-beta-D-galactosyl-R."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "guanosine diphosphofucose-galactoside 2-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "H-gene-encoded beta-galactoside alpha-1->2 fucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactoside 2-alpha-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "guanosine diphosphofucose-glycoprotein 2-alpha-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "blood-group substance H-dependent fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "guanosine diphosphofucose-galactosylacetylglucosaminylgalactosyl-glucosylceramide alpha-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "guanosine diphosphofucose-galactosylacetylglucosaminylgalactosylglucosylceramide alpha-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "guanosine diphosphofucose-glycoprotein 2-alpha-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "H-gene-encoded beta-galactoside alpha1->2 fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "secretor-type beta-galactoside alpha-1->2 fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "alpha-(1->2)-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "GDP fucose-lactose fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "alpha-2-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "secretor-type beta-galactoside alpha1->2 fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "beta-galactoside alpha1->2 fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "GDP-beta-L-fucose:beta-D-galactosyl-R 2-alpha-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion( "alpha(1,2)-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "guanosine diphosphofucose-beta-D-galactosyl-alpha-2-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.69"^^xsd:string) "beta-galactoside alpha-1->2 fucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.12"^^xsd:string) "hexose 1-phosphate uridyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.12"^^xsd:string) "uridyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.12"^^xsd:string) "UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.12"^^xsd:string) "hexose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.12"^^xsd:string) "Gal-1-P uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.12"^^xsd:string) "UDPglucose:alpha-D-galactose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.12"^^xsd:string) "UDP-glucose-hexose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.12"^^xsd:string) Annotation( "RHEA:13992"^^xsd:string) "Catalysis of the reaction: alpha-D-galactose 1-phosphate + UDP-D-glucose = alpha-D-glucose 1-phosphate + UDP-D-galactose."^^xsd:string) AnnotationAssertion(rdfs:label "UDP-glucose:hexose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.12"^^xsd:string) "galactose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.12"^^xsd:string) "uridyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.12"^^xsd:string) "uridylyl removing enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.12"^^xsd:string) "UDPglucose-hexose-1-phosphate uridylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.150"^^xsd:string) "N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.150"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.150"^^xsd:string) "galbeta1->4GlcNAc-R beta1->6 N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.150"^^xsd:string) "uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->6-acetylglucosaminyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.150"^^xsd:string) "N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.150"^^xsd:string) "UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide beta-1,6-N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.150"^^xsd:string) "UDP-GlcNAc:Gal-R, beta-D-6-N-acetylglucosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.38"^^xsd:string) "histidine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.38"^^xsd:string) Annotation( "RHEA:16568"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + L-histidine = 3-(imidazol-5-yl)pyruvate + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.38"^^xsd:string) "histidine-2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-histidine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion( "histidine aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-methylacyl-CoA racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.99.4"^^xsd:string) "2-methylacyl-CoA 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.99.4"^^xsd:string) "Catalysis of the reaction: (2S)-2-methylacyl-CoA = (2R)-2-methylacyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.1"^^xsd:string) Annotation( "RHEA:23887"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinamide = 1-methylnicotinamide + S-adenosyl-L-homocysteine."^^xsd:string) AnnotationAssertion(rdfs:label "nicotinamide N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.1"^^xsd:string) "nicotinamide methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.1"^^xsd:string) "S-adenosyl-L-methionine:nicotinamide N-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.4.11"^^xsd:string) "peptide-L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (S)-S-oxide-forming] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.11"^^xsd:string) "peptide Met(O) reductase activity"^^xsd:string) AnnotationAssertion( "peptide-methionine-(S)-S-oxide reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "peptide-methionine (S)-S-oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.11"^^xsd:string) "MsrA"^^xsd:string) AnnotationAssertion( "protein-methionine-S-oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.11"^^xsd:string) "methionine S-oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.11"^^xsd:string) "methionine sulfoxide reductase activity"^^xsd:string) AnnotationAssertion( "methionine sulfoxide (protein) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.11"^^xsd:string) "peptide methionine sulfoxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.11"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:11169920"^^xsd:string) "Catalysis of the reactions: peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin, and L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the S enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.11"^^xsd:string) "methionine sulfoxide reductase A activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.11"^^xsd:string) "methionine sulphoxide reductase A activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.11"^^xsd:string) "methionine S-oxide reductase (S-form oxidizing) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.43"^^xsd:string) "6-phosphogluconate dehydrogenase (NAD)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.43"^^xsd:string) "Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = 6-phospho-2-dehydro-D-gluconate + NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "phosphogluconate 2-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.43"^^xsd:string) "2-keto-6-phosphogluconate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.43"^^xsd:string) "gluconate 6-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.43"^^xsd:string) "phosphogluconate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.43"^^xsd:string) "6-phospho-D-gluconate:NAD(P)+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion( "6-phosphogluconate 2-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.43"^^xsd:string) "6-phosphogluconic dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.3.1"^^xsd:string) "sarcosine:oxygen oxidoreductase (demethylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.1"^^xsd:string) Annotation( "RHEA:13316"^^xsd:string) "Catalysis of the reaction: H(2)O + O(2) + sarcosine = formaldehyde + glycine + H(2)O(2)."^^xsd:string) AnnotationAssertion(rdfs:label "sarcosine oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.99.4"^^xsd:string) "PGI(2) synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.4"^^xsd:string) "PGI2 synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.4"^^xsd:string) "PGI2 synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "prostaglandin-I synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.4"^^xsd:string) "prostagladin I2 synthetase activity"^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP8A1"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.4"^^xsd:string) "prostacyclin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.4"^^xsd:string) "(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.4"^^xsd:string) "prostacycline synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.4"^^xsd:string) Annotation( "RHEA:23583"^^xsd:string) "Catalysis of the reaction: prostaglandin H(2) = prostaglandin I(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.4"^^xsd:string) "PGI(2) synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.27"^^xsd:string) "sphinganine-1-phosphate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.27"^^xsd:string) "sphinganine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.27"^^xsd:string) "sphinganine-1-phosphate alkanal-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.27"^^xsd:string) "Catalysis of the reaction: sphinganine 1-phosphate = phosphoethanolamine + palmitaldehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.27"^^xsd:string) "sphinganine-1-phosphate palmitaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.27"^^xsd:string) "sphingosine-1-phosphate aldolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sphinganine-1-phosphate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.27"^^xsd:string) "dihydrosphingosine 1-phosphate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.27"^^xsd:string) "sphingosine-1-phosphate lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.99.6"^^xsd:string) "SiaT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.6"^^xsd:string) "cytidine monophosphoacetylneuraminate-beta-galactosyl(1->4)acetylglucosaminide alpha2->3-sialyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetyllactosaminide alpha-2,3-sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.6"^^xsd:string) "CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein alpha-2,3-N-acetylneuraminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.6"^^xsd:string) "alpha2->3 sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.6"^^xsd:string) "Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.67"^^xsd:string) "thiopurine methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiopurine S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.67"^^xsd:string) "mercaptopurine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.67"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.67"^^xsd:string) "TPMT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.67"^^xsd:string) "6-thiopurine transmethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.67"^^xsd:string) "S-adenosyl-L-methionine:thiopurine S-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.80"^^xsd:string) "ceramide:UDPGlc glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.80"^^xsd:string) "UDPglucose:N-acylsphingosine D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.80"^^xsd:string) "Catalysis of the reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.80"^^xsd:string) "UDP-glucose:N-acylsphingosine D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.80"^^xsd:string) "UDP-glucose:ceramide glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ceramide glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.80"^^xsd:string) "UDP-glucose-ceramide glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.80"^^xsd:string) "ceramide:UDP-glucose glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.80"^^xsd:string) "glucosylceramide synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.80"^^xsd:string) "uridine diphosphoglucose-ceramide glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "ubiquinol:ferricytochrome-c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "reduced coenzyme Q-cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "ubiquinol-cytochrome c2 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "ubiquinol-cytochrome c1 oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ubiquinol-cytochrome-c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "reduced ubiquinone-cytochrome c reductase, complex III (mitochondrial electron transport)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "ubiquinol-cytochrome c-2 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "complex III (mitochondrial electron transport) activity"^^xsd:string) AnnotationAssertion( "cytochrome bc1 complex"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "coenzyme QH2-cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "mitochondrial electron transport complex III"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "reduced ubiquinone-cytochrome c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "ubiquinol-cytochrome c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: CoQH2 + 2 ferricytochrome c = CoQ + 2 ferrocytochrome c + 2 H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "ubihydroquinol:cytochrome c oxidoreductase activity"^^xsd:string) AnnotationAssertion( "ubiquinone-cytochrome b-c1 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "QH2:cytochrome c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "ubiquinone--cytochrome-c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "ubiquinone-cytochrome c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "coenzyme Q-cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "ubiquinone-cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "dihydrocoenzyme Q-cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.2"^^xsd:string) "CoQH2-cytochrome c oxidoreductase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.17"^^xsd:string) "cholesterol 7alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion( "cholesterol 7-alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cholesterol 7-alpha-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.17"^^xsd:string) "Catalysis of the reaction: cholesterol + NADPH + H+ + O2 = 7-alpha-hydroxycholesterol + NADP+ + H2O."^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP7A1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.17"^^xsd:string) "cholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.17"^^xsd:string) "cholesterol 7alpha-monooxygenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.96"^^xsd:string) Annotation( "RHEA:11923"^^xsd:string) "Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H(2)O."^^xsd:string) AnnotationAssertion(rdfs:label "4-alpha-hydroxytetrahydrobiopterin dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.96"^^xsd:string) "pterin-4alpha-carbinolamine dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.96"^^xsd:string) "(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin hydro-lyase [(6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin-forming]"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.96"^^xsd:string) "4alpha-hydroxy-tetrahydropterin dehydratase activity"^^xsd:string) AnnotationAssertion( "4a-hydroxytetrahydrobiopterin dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.96"^^xsd:string) "tetrahydrobiopterin dehydratase activity"^^xsd:string) AnnotationAssertion( "pterin-4a-carbinolamine dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.96"^^xsd:string) "4-alpha-hydroxy-tetrahydropterin dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.96"^^xsd:string) "4a-hydroxytetrahydrobiopterin hydro-lyase activity"^^xsd:string) AnnotationAssertion( "pterin-4-alpha-carbinolamine dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.6"^^xsd:string) "Catalysis of the reaction: an acetic ester + H2O = an alcohol + acetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.6"^^xsd:string) "acetic ester hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetylesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.6"^^xsd:string) "C-esterase (in animal tissues)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.6"^^xsd:string) "acetic-ester acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.6"^^xsd:string) "citrus acetylesterase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.6"^^xsd:string) "chloroesterase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.6"^^xsd:string) "p-nitrophenyl acetate esterase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.24"^^xsd:string) Annotation( "RHEA:15384"^^xsd:string) "Catalysis of the reaction: H(+) + O(2) + quercetin = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO."^^xsd:string) AnnotationAssertion(rdfs:label "quercetin 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.24"^^xsd:string) "quercetinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.24"^^xsd:string) "quercetin:oxygen 2,3-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.24"^^xsd:string) "flavonol 2,4-oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.3.21"^^xsd:string) Annotation( ) "primary-amine:oxygen oxidoreductase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.21"^^xsd:string) "amine oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "primary amine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.21"^^xsd:string) Annotation( "EC:1.4.3.22"^^xsd:string) Annotation( "EC:1.4.3.4"^^xsd:string) Annotation( "MetaCyc:RXN-9597"^^xsd:string) "Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide."^^xsd:string) AnnotationAssertion( "amine oxidase (copper-containing) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription."^^xsd:string) AnnotationAssertion(rdfs:label "transcription factor binding"^^xsd:string) AnnotationAssertion( "TF binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "translation factor activity, RNA binding"^^xsd:string) AnnotationAssertion(rdfs:label "translation factor activity, nucleic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Functions during translation by interacting selectively and non-covalently with nucleic acids during polypeptide synthesis at the ribosome."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "complex 1 dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "NADH dehydrogenase (ubiquinone) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "NADH-ubiquinone-1 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "NADH-Q6 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "mitochondrial electron transport complex I activity"^^xsd:string) AnnotationAssertion( "ubiquinone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "dihydronicotinamide adenine dinucleotide-coenzyme Q reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "NADH:ubiquinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "NADH-ubiquinone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "complex I (electron transport chain) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "mitochondrial electron transport complex 1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "NADH-coenzyme Q reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "DPNH-coenzyme Q reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "NADH-ubiquinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "NADH-CoQ reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "complex I (mitochondrial electron transport) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "NADH-CoQ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "NADH:ubiquinone oxidoreductase complex activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "type 1 dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "coenzyme Q reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "NADH coenzyme Q1 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "DPNH-ubiquinone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "electron transfer complex I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "complex I (NADH:Q1 oxidoreductase) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "Catalysis of the reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "NADH-coenzyme Q oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.3"^^xsd:string) "reduced nicotinamide adenine dinucleotide-coenzyme Q reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein tyrosine/serine/threonine phosphatase activity"^^xsd:string) AnnotationAssertion( "dual-specificity protein phosphatase"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "NLS binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "nuclear localisation sequence binding"^^xsd:string) AnnotationAssertion(rdfs:label "nuclear localization sequence binding"^^xsd:string) AnnotationAssertion( "nuclear localization signal binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a nuclear localization sequence, a specific peptide sequence that acts as a signal to localize the protein within the nucleus."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "adenosine 3',5'-cyclophosphate response element binding protein binding"^^xsd:string) AnnotationAssertion( "3',5' cAMP response element binding protein binding"^^xsd:string) AnnotationAssertion( "cyclic AMP response element binding protein binding"^^xsd:string) AnnotationAssertion(rdfs:label "cAMP response element binding protein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the cAMP response element binding protein."^^xsd:string) AnnotationAssertion( "CREB binding"^^xsd:string) AnnotationAssertion( "3',5'-cAMP response element binding protein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxysterol binding"^^xsd:string) AnnotationAssertion(Annotation( "http://www.onelook.com/"^^xsd:string) "Interacting selectively and non-covalently with oxysterol, an oxidized form of cholesterol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "poly-A binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "polyadenylate binding"^^xsd:string) AnnotationAssertion(rdfs:label "poly(A) binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "poly(rA) binding"^^xsd:string) AnnotationAssertion( "poly(A) binding, within an RNA molecule"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "drug binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with phenylalkylamine or any of its derivatives."^^xsd:string) AnnotationAssertion(rdfs:label "phenylalkylamine binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sulfotransferase activity"^^xsd:string) AnnotationAssertion( "sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "The action of a molecule that contributes to the structural integrity of bone."^^xsd:string) AnnotationAssertion(rdfs:label "structural constituent of bone"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the enzyme protein phosphatase 1."^^xsd:string) AnnotationAssertion(rdfs:label "protein phosphatase 1 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hedgehog receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:go_curators"^^xsd:string) Annotation( "PMID:9278137"^^xsd:string) "Combining with a member of the hedgehog protein family and transmitting the signal across the membrane to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "patched activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "protein tyrosine phosphatase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a tyrosyl phenolic group of a protein."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of a methyl group to an acceptor molecule."^^xsd:string) AnnotationAssertion( "methylase"^^xsd:string) AnnotationAssertion(rdfs:label "methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a methyl group to the carbon atom of an acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "C-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "N-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a methyl group to the sulfur atom of an acceptor molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "RNA methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "mRNA methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "tRNA methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.33"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.33"^^xsd:string) "N7-methylguanine methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.33"^^xsd:string) "7-methylguanine transfer ribonucleate methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.33"^^xsd:string) "S-adenosyl-L-methionine:tRNA (guanine-N7-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA (guanine-N7-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.33"^^xsd:string) "S-adenosyl-L-methionine:tRNA (guanine-7-N-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.33"^^xsd:string) "tRNA guanine 7-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.33"^^xsd:string) "transfer ribonucleate guanine 7-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.5.1"^^xsd:string) "succinic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.5.1"^^xsd:string) "succinate:ubiquinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.5.1"^^xsd:string) "menaquinol: fumarate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.5.1"^^xsd:string) "succinate dehydrogenase complex (i. e. SDH, involved in aerobic respiration, repressed in anaerobic respiration)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.5.1"^^xsd:string) "complex II"^^xsd:string) AnnotationAssertion(rdfs:label "succinate dehydrogenase (ubiquinone) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.5.1"^^xsd:string) Annotation( "RHEA:13716"^^xsd:string) "Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol."^^xsd:string) AnnotationAssertion( "quinol:fumarate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.5.1"^^xsd:string) "fumarate reductase complex (i.e. FRD, involved in anaerobic respiration, repressed in aerobic respiration)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the enzyme adenylate cyclase."^^xsd:string) AnnotationAssertion(rdfs:label "adenylate cyclase binding"^^xsd:string) AnnotationAssertion( "adenylyl cyclase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.1"^^xsd:string) Annotation( "MetaCyc:GLYCOPHOSPHORYL-RXN"^^xsd:string) "Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "glycogen phosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction."^^xsd:string) AnnotationAssertion(rdfs:label "RNA-dependent ATPase activity"^^xsd:string) AnnotationAssertion( "RNA-dependent adenosinetriphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "poly-pyrimidine tract binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with any stretch of pyrimidines (cytosine or uracil) in an RNA molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "neuropeptide receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Combining with a neuropeptide to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "eukaryotic initiation factor 4E binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with eukaryotic initiation factor 4E, a polypeptide factor involved in the initiation of ribosome-mediated translation."^^xsd:string) AnnotationAssertion( "eIF4E binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "metalloprotease inhibitor"^^xsd:string) AnnotationAssertion( "metalloproteinase inhibitor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity."^^xsd:string) AnnotationAssertion(rdfs:label "metalloendopeptidase inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of an RNA molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:1660461"^^xsd:string) "Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of a tRNA molecule; observed for His tRNAs."^^xsd:string) AnnotationAssertion(rdfs:label "tRNA guanylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "InterPro:IPR004224"^^xsd:string) Annotation( "PMID:11846783"^^xsd:string) "Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule."^^xsd:string) AnnotationAssertion(rdfs:label "UDP-glycosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.4"^^xsd:string) "phosphatic acid phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.4"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) "Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.4"^^xsd:string) "acid phosphatidyl phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.4"^^xsd:string) "phosphatidic acid phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.4"^^xsd:string) "phosphatic acid phosphohydrolase activity"^^xsd:string) AnnotationAssertion( "phosphatidate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.4"^^xsd:string) "3-sn-phosphatidate phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:12429745"^^xsd:string) "Receiving vitellogenin, and delivering vitellogenin into the cell via endocytosis."^^xsd:string) AnnotationAssertion(rdfs:label "vitellogenin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with ferrous iron, Fe(II)."^^xsd:string) AnnotationAssertion(rdfs:label "ferrous iron binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with ferric iron, Fe(III)."^^xsd:string) AnnotationAssertion(rdfs:label "ferric iron binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ion channel inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stops, prevents, or reduces the activity of an ion channel."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "heparan sulfate binding"^^xsd:string) AnnotationAssertion(rdfs:label "heparin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tyramine receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "http://www.onelook.com/"^^xsd:string) "Combining with the biogenic amine tyramine to initiate a change in cell activity. Tyramine is a sympathomimetic amine derived from tyrosine with an action resembling that of epinephrine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) "Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "amine receptor activity, G-protein coupled "^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled amine receptor activity"^^xsd:string) AnnotationAssertion( "biogenic amine receptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0815332181"^^xsd:string) "Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid."^^xsd:string) AnnotationAssertion( "peptide hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "peptidase activity"^^xsd:string) AnnotationAssertion( "proteinase activity"^^xsd:string) AnnotationAssertion( "protease activity"^^xsd:string) AnnotationAssertion( "hydrolase, acting on peptide bonds"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cysteine-type peptidase activity"^^xsd:string) AnnotationAssertion( "cysteine protease activity"^^xsd:string) AnnotationAssertion( "thiol protease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#EXOPEPTIDASE"^^xsd:string) "Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions."^^xsd:string) AnnotationAssertion(rdfs:label "metalloexopeptidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0716720094"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)."^^xsd:string) AnnotationAssertion( "serine protease activity"^^xsd:string) AnnotationAssertion(rdfs:label "serine-type peptidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "metallopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "metalloprotease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "metalloproteinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) "Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "exopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#EXOPEPTIDASE"^^xsd:string) "Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both."^^xsd:string) AnnotationAssertion( "exoprotease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dipeptidyl-peptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mb"^^xsd:string) "Catalysis of the hydrolysis of N-terminal dipeptides from a polypeptide chain."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tripeptidyl-peptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the release of an N-terminal tripeptide from a polypeptide."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mb"^^xsd:string) "Catalysis of the release of C-terminal dipeptides from a polypeptide chain."^^xsd:string) AnnotationAssertion(rdfs:label "peptidyl-dipeptidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "omega peptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.19.-"^^xsd:string) "Catalysis of the removal of terminal peptide residues that are substituted, cyclized or linked by isopeptide bonds (peptide linkages other than those of alpha-carboxyl to alpha-amino groups)."^^xsd:string) AnnotationAssertion( "peptidase activity, acting on peptides containing modified amino acids"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tRNA-specific adenosine deaminase activity"^^xsd:string) AnnotationAssertion( "tRNA-adenosine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "IMG:00700"^^xsd:string) "Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a tRNA molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.31"^^xsd:string) "Catalysis of the reaction: a nucleotide + H2O = a nucleoside + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "nucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.31"^^xsd:string) "deoxyribonucleoside-activated nucleotidase (DAN)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.31"^^xsd:string) "nucleotide phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.31"^^xsd:string) "nucleotide-specific phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.31"^^xsd:string) "NSP I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.31"^^xsd:string) "NSP II"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.31"^^xsd:string) "acid nucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.31"^^xsd:string) "deoxyinosine-activated nucleotidase (DIAN)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "5' nucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.5"^^xsd:string) "snake venom 5'-nucleotidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.5"^^xsd:string) "5'-AMP nucleotidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.5"^^xsd:string) "adenosine monophosphatase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.5"^^xsd:string) "uridine 5'-nucleotidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.5"^^xsd:string) "adenosine 5'-phosphatase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.5"^^xsd:string) "UMPase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.5"^^xsd:string) "AMP phosphohydrolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.5"^^xsd:string) "AMPase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.5"^^xsd:string) "5'-AMPase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.5"^^xsd:string) "AMP phosphatase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.5"^^xsd:string) "5'-ribonucleotide phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.5"^^xsd:string) "thimidine monophosphate nucleotidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.5"^^xsd:string) "5'-mononucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.5"^^xsd:string) "5'-adenylic phosphatase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.5"^^xsd:string) "Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "5'-nucleotidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.6"^^xsd:string) "3'-ribonucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.6"^^xsd:string) "3'-mononucleotidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3'-nucleotidase activity"^^xsd:string) AnnotationAssertion( "3' nucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.6"^^xsd:string) "3'-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.6"^^xsd:string) "3'-ribonucleotide phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.6"^^xsd:string) "Catalysis of the reaction: a 3'-ribonucleotide + H2O = a ribonucleoside + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ecdysis-triggering hormone activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9020043"^^xsd:string) "The action characteristic of ecdysis-triggering hormone, a peptide hormone that, upon receptor binding, initiates pre-ecdysis and ecdysis (i.e. cuticle shedding) through direct action on the central nervous system."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.13.1"^^xsd:string) "protein-histidine pros-kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein histidine pros-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.1"^^xsd:string) "ATP:protein-L-histidine N-pros-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.1"^^xsd:string) "Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(pi)-phospho-L-histidine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.1"^^xsd:string) "ATP:protein-L-histidine Npi-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.1"^^xsd:string) "HK2"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.13.2"^^xsd:string) "HK3"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.2"^^xsd:string) "protein-histidine tele-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.2"^^xsd:string) "ATP:protein-L-histidine Ntau-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.2"^^xsd:string) "ATP:protein-L-histidine N-tele-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.13.2"^^xsd:string) "Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(tau)-phospho-L-histidine."^^xsd:string) AnnotationAssertion(rdfs:label "protein histidine tele-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.3.5"^^xsd:string) "3-oxoacid coenzyme A-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.5"^^xsd:string) "succinyl coenzyme A-acetoacetyl coenzyme A-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.5"^^xsd:string) "acetoacetyl coenzyme A-succinic thiophorase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.5"^^xsd:string) "3-ketoacid coenzyme A transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.5"^^xsd:string) "acetoacetate succinyl-CoA transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-oxoacid CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.5"^^xsd:string) "Catalysis of the reaction: succinyl-CoA + a 3-oxo acid = succinate + a 3-oxo-acyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.5"^^xsd:string) "succinyl-CoA:3-oxo-acid CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.5"^^xsd:string) "3-oxoacid CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.5"^^xsd:string) "succinyl-CoA transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.5"^^xsd:string) "3-ketoacid CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.5"^^xsd:string) "3-oxo-CoA transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.5"^^xsd:string) "succinyl-CoA:3-ketoacid-CoA transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "allatostatin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Combining with allatostatin to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:12486120"^^xsd:string) "Interacting selectively and non-covalently with importin-alpha to mediate its transfer through the nuclear pore to the cytoplasm."^^xsd:string) AnnotationAssertion( "importin-alpha binding"^^xsd:string) AnnotationAssertion(rdfs:label "importin-alpha export receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "G/T-mismatch-specific thymine-DNA glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:9224623"^^xsd:string) "Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site."^^xsd:string) AnnotationAssertion(rdfs:label "pyrimidine-specific mismatch base pair DNA N-glycosylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:11549764"^^xsd:string) "Catalysis of the sulfurylation of the desulfo form of molybdenum cofactor (MoCo), a cofactor required for the activity of some enzymes, such as aldehyde oxidase."^^xsd:string) AnnotationAssertion( "molybdopterin synthase sulfurylase activity"^^xsd:string) AnnotationAssertion( "molybdopterin cofactor sulfurase activity"^^xsd:string) AnnotationAssertion(rdfs:label "Mo-molybdopterin cofactor sulfurase activity"^^xsd:string) AnnotationAssertion( "Mo-molybdopterin cofactor sulphurase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a sequence of uracil residues in an RNA molecule."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "poly(U) binding"^^xsd:string) AnnotationAssertion(rdfs:label "poly(U) RNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "poly-glutamine tract binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a polyglutamine tract, i.e. a series of consecutive glutamine residues, in a protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "JAK pathway signal transduction adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_MIT_16mar07"^^xsd:string) "The binding activity of a molecule that brings together two molecules of the JAK signal transduction pathway, permitting them to function in a coordinated way."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "zinc binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with zinc (Zn) ions."^^xsd:string) AnnotationAssertion(rdfs:label "zinc ion binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sulphate porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "secondary active sulfate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "secondary active sulphate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "sulfate porter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the secondary active transfer of sulfate from one side of the membrane to the other. Secondary active transport is catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.19.4.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + K+(in) + Na+(out) = Ca2+(out) + K+(out) + Na+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "calcium, potassium:sodium antiporter activity"^^xsd:string) AnnotationAssertion( "potassium-dependent sodium/calcium exchanger"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of a methyl group (CH3-) to a protein."^^xsd:string) AnnotationAssertion(rdfs:label "protein methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sulfonylurea receptor activity"^^xsd:string) AnnotationAssertion( "sulphonylurea receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with sulfonylurea, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with a protein bride of sevenless (boss) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "boss receptor activity"^^xsd:string) AnnotationAssertion( "sevenless receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lipid binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a lipid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "calcium/calmodulin-responsive adenylate cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.1"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate, stimulated by calcium-bound calmodulin."^^xsd:string) AnnotationAssertion(rdfs:label "calcium- and calmodulin-responsive adenylate cyclase activity"^^xsd:string) AnnotationAssertion( "calcium- and calmodulin-responsive adenylyl cyclase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a DNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "3'-5'-exodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion( "3'-5' exodeoxyribonuclease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a single-stranded DNA molecule."^^xsd:string) AnnotationAssertion( "single-stranded DNA specific exodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "ssDNA-specific exodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(rdfs:label "single-stranded DNA exodeoxyribonuclease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "DNA bending involving DNA binding"^^xsd:string) AnnotationAssertion( "DNA bending activity"^^xsd:string) AnnotationAssertion(rdfs:label "DNA binding, bending"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:10710711"^^xsd:string) Annotation( "PMID:19037758"^^xsd:string) "The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "structural constituent of muscle"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "The action of a molecule that contributes to the structural integrity of a muscle fiber."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "voltage-gated anion channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion( "voltage-dependent ion-selective channel activity"^^xsd:string) AnnotationAssertion( "voltage-gated ion-selective channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a double-stranded DNA molecule."^^xsd:string) AnnotationAssertion( "double-stranded DNA specific exodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(rdfs:label "double-stranded DNA exodeoxyribonuclease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "ssDNA-specific 3'-5' exodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion( "single-stranded DNA specific 3'-5' exodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(rdfs:label "single-stranded DNA 3'-5' exodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:22562358"^^xsd:string) "Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a single-stranded DNA molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "double-stranded DNA 3'-5' exodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:22562358"^^xsd:string) "Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a double-stranded DNA molecule."^^xsd:string) AnnotationAssertion( "double-stranded DNA specific 3'-5' exodeoxyribonuclease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:6181418"^^xsd:string) "Interacting selectively and non-covalently with 7S RNA, the RNA component of the signal recognition particle (SRP)."^^xsd:string) AnnotationAssertion(rdfs:label "7S RNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Combining with the ligand Gurken to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "gurken-activated receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "gurken receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "structural constituent of vitelline membrane"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:sensu"^^xsd:string) "The action of a molecule that contributes to the structural integrity of the vitelline membrane of an egg. An example of this is found in Drosophila melanogaster."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the gurken growth factor receptor."^^xsd:string) AnnotationAssertion(rdfs:label "gurken receptor binding"^^xsd:string) AnnotationAssertion( "gurken receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein."^^xsd:string) AnnotationAssertion(rdfs:label "protein prenyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a protein from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "protein transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Ral guanyl-nucleotide exchange factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ral family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase."^^xsd:string) AnnotationAssertion( "Ral GDP-dissociation stimulator activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "transmembrane cation transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "cation transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dgf"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of cation from one side of the membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methyl-CpG binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:11746232"^^xsd:string) "Interacting selectively and non-covalently with a methylated cytosine/guanine dinucleotide."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "macrophage receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ar"^^xsd:string) Annotation( "PMID:12507420"^^xsd:string) Annotation( "PMID:12925128"^^xsd:string) Annotation( "PMID:14523544"^^xsd:string) Annotation( "Wikipedia:Pattern_recognition_receptor"^^xsd:string) "Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species, or damage-associated molecular pattern (DAMP), an endogenous molecule released from damaged cells), and transmitting a signal to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "signaling pattern recognition receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "Wikipedia:Pattern_recognition_receptor"^^xsd:string) "signaling PRR activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reactions: protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "protein tyrosine/threonine phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Q-type calcium channel"^^xsd:string) AnnotationAssertion(rdfs:label "high voltage-gated calcium channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "PMID:16382099"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a high voltage-gated channel. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion( "high voltage-dependent calcium channel activity"^^xsd:string) AnnotationAssertion( "L-type calcium channel"^^xsd:string) AnnotationAssertion( "P-type calcium channel"^^xsd:string) AnnotationAssertion( "N-type calcium channel"^^xsd:string) AnnotationAssertion( "high voltage gated calcium channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "T-type calcium channel"^^xsd:string) AnnotationAssertion(rdfs:label "low voltage-gated calcium channel activity"^^xsd:string) AnnotationAssertion( "low voltage gated calcium channel activity"^^xsd:string) AnnotationAssertion( "low voltage-dependent calcium channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "PMID:16382099"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a low voltage-gated channel. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "g-butyrobetaine dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "gamma-butyrobetaine dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.1"^^xsd:string) Annotation( "RHEA:24031"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + 4-(trimethylammonio)butanoate + O(2) = carnitine + CO(2) + succinate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.1"^^xsd:string) "butyrobetaine hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.1"^^xsd:string) "gamma-BBH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.1"^^xsd:string) "gamma-butyrobetaine hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.1"^^xsd:string) "4-trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)"^^xsd:string) AnnotationAssertion( "gamma-butyrobetaine,2-oxoglutarate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.1"^^xsd:string) "alpha-butyrobetaine hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:20811974"^^xsd:string) "MAP4K activity"^^xsd:string) AnnotationAssertion( "MAPKKKK"^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase kinase kinase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:11790549"^^xsd:string) "Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.23"^^xsd:string) "RNA-polymerase-subunit kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.23"^^xsd:string) "ATP:DNA-directed RNA polymerase phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.23"^^xsd:string) "RNA polymerase subunit kinase activity"^^xsd:string) AnnotationAssertion( "[RNA-polymerase]-subunit kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.23"^^xsd:string) "CTD kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II carboxy-terminal domain kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.23"^^xsd:string) "STK9"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.23"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA polymerase II); phosphorylation occurs on residues in the carboxy-terminal domain (CTD) repeats."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.99"^^xsd:string) Annotation( "GOC:cjm"^^xsd:string) Annotation( "Wikipedia:Sialyltransferase"^^xsd:string) "Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins."^^xsd:string) AnnotationAssertion(rdfs:label "sialyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an acyl group to an oxygen atom on the acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "O-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion( "GlcNAc transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to a sugar."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an oligosaccharide."^^xsd:string) AnnotationAssertion( "GalNAc transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetylgalactosaminyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thioredoxin peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-267"^^xsd:string) "Catalysis of the reaction: thioredoxin + hydrogen peroxide = thioredoxin disulfide + H2O."^^xsd:string) AnnotationAssertion( "TrxPx activity"^^xsd:string) AnnotationAssertion( "TPx activity"^^xsd:string) AnnotationAssertion( "thiol peroxidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mechanically-gated ion channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.10"^^xsd:string) "TBK1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.10"^^xsd:string) "inhibitor of NFkappaB kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "IkappaB kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.10"^^xsd:string) "ikappaB kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.10"^^xsd:string) "IKBKB"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.10"^^xsd:string) "IKK-2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.10"^^xsd:string) "STK12"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.10"^^xsd:string) "IKBKA"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.10"^^xsd:string) "IKK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.10"^^xsd:string) "inhibitor of NF-kappaB kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.10"^^xsd:string) "ATP:IkappaB protein phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.10"^^xsd:string) "CHUK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.10"^^xsd:string) "TANK-binding kinase 1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.10"^^xsd:string) "Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.10"^^xsd:string) "IKK-1"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.15.6"^^xsd:string) "cholesterol side-chain-cleaving enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.6"^^xsd:string) "cytochrome p450scc"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.6"^^xsd:string) "cholesterol C20-22 desmolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.6"^^xsd:string) "Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.6"^^xsd:string) "desmolase, steroid 20-22"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.6"^^xsd:string) "cytochrome p450(scc) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.6"^^xsd:string) "cholesterol desmolase activity"^^xsd:string) AnnotationAssertion( "Cyp11a1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.6"^^xsd:string) "cholesterol side-chain cleavage enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.6"^^xsd:string) "enzymes, cholesterol side-chain-cleaving"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.6"^^xsd:string) "C27-side chain cleavage enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.6"^^xsd:string) "cytochrome P-450(scc) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.6"^^xsd:string) "cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.6"^^xsd:string) "steroid 20-22 desmolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.6"^^xsd:string) "cytochrome P-450scc"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.6"^^xsd:string) "cholesterol 20-22-desmolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cholesterol monooxygenase (side-chain-cleaving) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.6"^^xsd:string) "cholesterol C(20-22) desmolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.6"^^xsd:string) "steroid 20-22-lyase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cytochrome P450 CYP2A12"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: a steroid + donor-H2 + O2 = 7-alpha-hydroxysteroid + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "steroid 7-alpha-hydroxylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "testosterone 15-alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP2A4"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: testosterone + donor-H2 + O2 = 15-alpha-hydroxytestosterone + H2O."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cytochrome P450 CYP2A5"^^xsd:string) AnnotationAssertion(rdfs:label "coumarin 7-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "Reactome:163103"^^xsd:string) "Catalysis of the reaction: coumarin + O2 + NADPH + H+ = hydroxycoumarin + H2O + NADP+."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cytochrome P450 CYP2B9"^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP2B10"^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP2D11"^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP2D9"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: testosterone + donor-H2 + O2 = 6-alpha-hydroxytestosterone + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "testosterone 16-alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP2D10"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the incorporation of one atom from molecular oxygen into arachidonic acid and the reduction of the other atom of oxygen to water."^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP2B19"^^xsd:string) AnnotationAssertion(rdfs:label "arachidonic acid monooxygenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arachidonic acid epoxygenase activity"^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP2J5"^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP2J6"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10681399"^^xsd:string) Annotation( "http://lipidlibrary.aocs.org/Lipids/eic_hete/index.htm"^^xsd:string) "Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cytochrome P450 CYP2G1"^^xsd:string) AnnotationAssertion(rdfs:label "steroid hydroxylase activity"^^xsd:string) AnnotationAssertion( "olfactory-specific steroid hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0721662544"^^xsd:string) "Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10882791"^^xsd:string) "Catalysis of the reaction: an oxysterol + NADPH + O2 = 7-alpha-hydroxylated oxysterol + NADP+ + H2O."^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP7B1"^^xsd:string) AnnotationAssertion(rdfs:label "oxysterol 7-alpha-hydroxylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sterol 12-alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: a steroid + donor-H2 + O2 = 12-alpha-hydroxysteroid + H2O."^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP8B1"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.70"^^xsd:string) "lanosterol 14-demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.70"^^xsd:string) "obtusufoliol 14-demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.70"^^xsd:string) "cytochrome P450 51 activity"^^xsd:string) AnnotationAssertion(rdfs:label "sterol 14-demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.70"^^xsd:string) "sterol 14-alpha-demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.70"^^xsd:string) "sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.70"^^xsd:string) "lanosterol 14-alpha-demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.70"^^xsd:string) "sterol 14alpha-demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.70"^^xsd:string) "lanosterol 14alpha-demethylase activity"^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP51"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.70"^^xsd:string) "Catalysis of the reaction: obtusifoliol + 3 O2 + 3 NADPH + 3 H+ = 4-alpha-methyl-5-alpha-ergosta-8,14,24(28)-trien-3-beta-ol + formate + 3 NADP+ + 3 H2O."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cytochrome P450 CYP2F2"^^xsd:string) AnnotationAssertion(Annotation( "PMID:1742282"^^xsd:string) Annotation( "PMID:1981702"^^xsd:string) "Catalysis of the conversion of naphthalene to naphthalene 1,2-oxide."^^xsd:string) AnnotationAssertion(rdfs:label "naphthalene hydroxylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "retinoic acid 4-hydroxylase activity"^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP261"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19519282"^^xsd:string) "Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "25-hydroxyvitamin D3 24-hydroxylase activity"^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP24"^^xsd:string) AnnotationAssertion(rdfs:label "25-hydroxycholecalciferol-24-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0471331309"^^xsd:string) "Catalysis of the hydroxylation of C-24 of 25-hydroxycholecalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycholecalciferol."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10681399"^^xsd:string) Annotation( "http://lipidlibrary.aocs.org/Lipids/eic_hete/index.htm"^^xsd:string) "Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-14,15-epoxyeicosatrienoic acid."^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP2C29"^^xsd:string) AnnotationAssertion(rdfs:label "arachidonic acid 14,15-epoxygenase activity"^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP2C39"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arachidonic acid 11,12-epoxygenase activity"^^xsd:string) AnnotationAssertion( "cytochrome P450 CYP2C38"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10681399"^^xsd:string) Annotation( "http://lipidlibrary.aocs.org/Lipids/eic_hete/index.htm"^^xsd:string) "Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-11,12-epoxyeicosatrienoic acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end."^^xsd:string) AnnotationAssertion(rdfs:label "3'-5' exonuclease activity"^^xsd:string) AnnotationAssertion( "3'-5'-exonuclease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 5' end."^^xsd:string) AnnotationAssertion(rdfs:label "5'-3' exonuclease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a coenzyme A (CoA) group from one compound (donor) to another (acceptor)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-hydroxybutyrate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a coenzyme A (CoA) group to 4-hydroxybutyrate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "para-hydroxybenzoate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:4OHBENZOATE-OCTAPRENYLTRANSFER-RXN"^^xsd:string) "Catalysis of the reaction: farnesylfarnesylgeranyl diphosphate + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate."^^xsd:string) AnnotationAssertion( "PHB polyprenyl diphosphate transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxybenzoate octaprenyltransferase activity"^^xsd:string) AnnotationAssertion( "para-hydroxybenzoate:polyprenyltransferase activity"^^xsd:string) AnnotationAssertion( "para-hydroxybenzoate-polyprenyl diphosphate transferase activity"^^xsd:string) AnnotationAssertion( "4-HB polyprenyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "8-oxo-7,8-dihydroguanosine triphosphatase activity"^^xsd:string) AnnotationAssertion( "8-oxo-GTPase activity"^^xsd:string) AnnotationAssertion( "8-oxo-7,8-dihydroguanine triphosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15878881"^^xsd:string) "Catalysis of the reaction: 8-oxo-7,8-dihydroguanosine triphosphate = 8-oxo-7,8-dihydroguanosine phosphate + diphosphate. 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for transcription."^^xsd:string) AnnotationAssertion( "7,8-dihydro-8-oxoguanine-triphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a CDP-alcohol group from one compound to another."^^xsd:string) AnnotationAssertion(rdfs:label "CDP-alcohol phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "delta5-delta2,4-dienoyl-CoA isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11278886"^^xsd:string) "Catalysis of the isomerization of 3,5-dienoyl-CoA to 2,4-dienoyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein-N-terminal asparagine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8910481"^^xsd:string) "Catalysis of the reaction: protein-L-asparagine + H2O = protein-L-aspartate + NH3. This reaction is the deamidation of an N-terminal asparagine residue in a peptide or protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA lariat debranching enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:7519612"^^xsd:string) "Catalysis of the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "Catalysis of the reaction: phospho-(DNA-directed RNA polymerase) + H2O = (DNA-directed RNA polymerase) + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "CTD phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "long-chain fatty acyl-glutamate deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.55"^^xsd:string) "long-chain aminoacylase activity"^^xsd:string) AnnotationAssertion( "long-chain-fatty-acyl-glutamate deacylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "long-chain fatty-acyl-glutamate deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.55"^^xsd:string) "long-chain acylglutamate amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.55"^^xsd:string) "Catalysis of the reaction: N-long-chain-fatty-acyl-L-glutamate + H2O = a fatty acid anion + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.55"^^xsd:string) "N-long-chain-fatty-acyl-L-glutamate amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.21"^^xsd:string) "aryl-beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.21"^^xsd:string) "p-nitrophenyl beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.21"^^xsd:string) "amygdalase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.21"^^xsd:string) "beta-D-glucoside glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.21"^^xsd:string) "beta-1,6-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.21"^^xsd:string) "cellobiase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.21"^^xsd:string) "beta-D-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.21"^^xsd:string) "amygdalinase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.21"^^xsd:string) "limarase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.21"^^xsd:string) "beta-glucoside glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.21"^^xsd:string) "gentobiase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.21"^^xsd:string) "gentiobiase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.21"^^xsd:string) "primeverosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.21"^^xsd:string) "salicilinase activity"^^xsd:string) AnnotationAssertion( "cytokine beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.21"^^xsd:string) "elaterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.21"^^xsd:string) "Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.21"^^xsd:string) "arbutinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.21"^^xsd:string) "emulsin"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycoprotein 6-alpha-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.68"^^xsd:string) "GDPfucose-glycoprotein fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.68"^^xsd:string) "guanosine diphosphofucose--glycoprotein fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.68"^^xsd:string) "glycoprotein fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.68"^^xsd:string) "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1,6)fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.68"^^xsd:string) "FucT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.68"^^xsd:string) Annotation( "RHEA:12988"^^xsd:string) "Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->6)]-N-acetyl-beta-D-glucosaminyl}asparagine + GDP + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.68"^^xsd:string) "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1,6)fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.68"^^xsd:string) "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1->6)fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.68"^^xsd:string) "GDP-L-fucose--glycoprotein fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.68"^^xsd:string) "GDP-fucose--glycoprotein fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.68"^^xsd:string) "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1->6)fucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ubiquinone biosynthetic process methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity"^^xsd:string) AnnotationAssertion( "ubiquinone biosynthesis methyltransferase activity"^^xsd:string) AnnotationAssertion( "2-polyprenyl-6-methoxy-1,4-benzoquinone methylase activity"^^xsd:string) AnnotationAssertion( "coenzyme Q biosynthesis methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kd"^^xsd:string) Annotation( "PMID:9083048"^^xsd:string) "Catalysis of the reaction: 2-polyprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine."^^xsd:string) AnnotationAssertion( "coenzyme Q biosynthetic process methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein kinase C inhibitor activity"^^xsd:string) AnnotationAssertion( "diacylglycerol-activated phospholipid-dependent protein kinase C inhibitor activity"^^xsd:string) AnnotationAssertion( "diacylglycerol-activated phospholipid-dependent PKC inhibitor activity"^^xsd:string) AnnotationAssertion( "PKC inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Stops, prevents or reduces the activity of protein kinase C, an enzyme which phosphorylates a protein."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "calcium-dependent protein kinase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stops, prevents or reduces the activity of a calcium-dependent protein kinase."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Stops, prevents or reduces the activity of a ribonuclease, any enzyme that catalyzes the hydrolysis of phosphodiester bonds in chains of RNA."^^xsd:string) AnnotationAssertion(rdfs:label "ribonuclease inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidylethanolamine binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with selenium (Se)."^^xsd:string) AnnotationAssertion(rdfs:label "selenium binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "vitamin E binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:33234"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) Annotation( "ISBN:0721662544"^^xsd:string) "Interacting selectively and non-covalently with vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant."^^xsd:string) AnnotationAssertion( "alpha-tocopherol binding"^^xsd:string) AnnotationAssertion( "tocopherol binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with JUN kinase, an enzyme that catalyzes the phosphorylation and activation of members of the JUN family."^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:ebc"^^xsd:string) "JNK binding"^^xsd:string) AnnotationAssertion(rdfs:label "JUN kinase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcitriol receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "Wikipedia:Calcitriol"^^xsd:string) "1,25-dihydroxyvitamin D3 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "Wikipedia:Calcitriol"^^xsd:string) "1,25-(OH)2D3 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16549446"^^xsd:string) " 1alpha,25(OH)2D3 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "Wikipedia:Calcitriol_receptor"^^xsd:string) "vitamin D3 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:17823"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:16549446"^^xsd:string) Annotation( "PMID:17082781"^^xsd:string) Annotation( "Wikipedia:Calcitriol_receptor"^^xsd:string) "Combining with calcitriol, the hormonally active form of vitamin D3, and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II."^^xsd:string) AnnotationAssertion(Annotation( "Wikipedia:Calcitriol"^^xsd:string) "1,25-dihydroxycholecalciferol receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:17823"^^xsd:string) "1alpha,25-dihydroxyvitamin D3 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "The action characteristic of thyrotropin-releasing hormone (TRH), a hormone released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary."^^xsd:string) AnnotationAssertion( "thyrotropin releasing hormone activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "TRH activity"^^xsd:string) AnnotationAssertion(rdfs:label "thyrotropin-releasing hormone activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.127"^^xsd:string) "ins(1,4,5)P(3) 3-kinase activity"^^xsd:string) AnnotationAssertion( "inositol trisphosphate 3-kinase activity"^^xsd:string) AnnotationAssertion( "inositol-trisphosphate 3-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.127"^^xsd:string) "IP3K activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.127"^^xsd:string) "Ins(1,4,5)P3 3-kinase activity"^^xsd:string) AnnotationAssertion( "1D-myo-inositol-trisphosphate 3-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.127"^^xsd:string) Annotation( "RHEA:11023"^^xsd:string) "Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "inositol-1,4,5-trisphosphate 3-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.127"^^xsd:string) "ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.127"^^xsd:string) "IP3 3-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.7"^^xsd:string) "adenosine-3'(2'),5'-bisphosphate 3'(2')-phosphohydrolase activity"^^xsd:string) AnnotationAssertion( "3'(2'),5' bisphosphate nucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.7"^^xsd:string) "3'-phosphoadenylylsulfate 3'-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.7"^^xsd:string) "phosphoadenylate 3'-nucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.7"^^xsd:string) "DPNPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3'(2'),5'-bisphosphate nucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.7"^^xsd:string) "Catalysis of the reaction: adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.7"^^xsd:string) "3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.31"^^xsd:string) "Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxyisobutyrate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a phosphate group, usually from ATP, to a fructose substrate molecule."^^xsd:string) AnnotationAssertion(rdfs:label "phosphofructokinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.5"^^xsd:string) "phosphatidylglycerolphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.5"^^xsd:string) "phosphatidylglycerophosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.5"^^xsd:string) "cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):sn-glycerol-3-phosphate phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.5"^^xsd:string) "phosphatidylglycerol phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.5"^^xsd:string) "CDPdiacylglycerol:sn-glycero-3-phosphate phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.5"^^xsd:string) "phosphatidylglycerol phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.5"^^xsd:string) "PGP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.5"^^xsd:string) "CDPdiacylglycerol-sn-glycerol-3-phosphate 3-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.5"^^xsd:string) "sn-glycerol-3-phosphate phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.5"^^xsd:string) "CDP-diacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.5"^^xsd:string) "glycerol phosphate phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.5"^^xsd:string) "CDPdiacylglycerol:glycerol-3-phosphate phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.5"^^xsd:string) "phosphatidylglycerophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.5"^^xsd:string) "3-phosphatidyl-1'-glycerol-3'-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.5"^^xsd:string) "glycerol 3-phosphate phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.5"^^xsd:string) "glycerophosphate phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.5"^^xsd:string) "CDPdiacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.5"^^xsd:string) Annotation( "RHEA:12596"^^xsd:string) "Catalysis of the reaction: sn-glycerol 3-phosphate + CDP-diacylglycerol = 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate + CMP + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.3.1"^^xsd:string) "D-aspartate:oxygen oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.1"^^xsd:string) "aspartic oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-aspartate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.1"^^xsd:string) "D-aspartic oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.1"^^xsd:string) "Catalysis of the reaction: D-aspartate + H2O + O2 = oxaloacetate + NH3 + hydrogen peroxide."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.47"^^xsd:string) "GDP-D-mannose 4,6-dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.47"^^xsd:string) "guanosine diphosphomannose 4,6-dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.47"^^xsd:string) "GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "GDP-mannose 4,6-dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.47"^^xsd:string) "GDP-mannose 4,6-hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.47"^^xsd:string) Annotation( "RHEA:23823"^^xsd:string) "Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.47"^^xsd:string) "guanosine diphosphomannose oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.47"^^xsd:string) "GDPmannose 4,6-dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.47"^^xsd:string) "guanosine 5'-diphosphate-D-mannose oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.47"^^xsd:string) "GDP-D-mannose dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.47"^^xsd:string) "Gmd"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.10.3.3"^^xsd:string) "ascorbic oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.3"^^xsd:string) "L-ascorbate:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.3"^^xsd:string) "ascorbase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.3"^^xsd:string) "ascorbic acid oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-ascorbate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.3"^^xsd:string) "ascorbate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.3"^^xsd:string) "AA oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.3"^^xsd:string) "L-ascorbic acid oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.3"^^xsd:string) "AAO"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.3"^^xsd:string) "Catalysis of the reaction: 2 L-ascorbate + O2 = 2 dehydroascorbate + 2 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.3"^^xsd:string) "L-ascorbate:O2 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.3"^^xsd:string) "ascorbate oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.25"^^xsd:string) "Catalysis of the reaction: N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.25"^^xsd:string) "acetylaminodeoxyglucosephosphate acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.25"^^xsd:string) "acetylglucosamine phosphate deacetylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylglucosamine-6-phosphate deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.25"^^xsd:string) "2-acetamido-2-deoxy-D-glucose-6-phosphate amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.25"^^xsd:string) "N-acetyl-D-glucosamine-6-phosphate amidohydrolase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-acetylglucosamine-6-sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.14"^^xsd:string) "N-acetylglucosamine 6-sulfate sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.14"^^xsd:string) "chondroitinsulfatase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.14"^^xsd:string) "glucosamine-6-sulfatase activity"^^xsd:string) AnnotationAssertion( "N-acetylglucosamine-6-sulphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.14"^^xsd:string) "N-acetyl-D-glucosamine-6-sulfate 6-sulfohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.14"^^xsd:string) "O,N-disulfate O-sulfohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.14"^^xsd:string) "2-acetamido-2-deoxy-D-glucose 6-sulfate sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.14"^^xsd:string) "acetylglucosamine 6-sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.14"^^xsd:string) "Catalysis of the hydrolysis of the 6-sulfate group of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the formation of a phosphodiester bond between a hydroxyl group at the end of one RNA chain and the 5'-phosphate group at the end of another."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alanine-glyoxylate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.44"^^xsd:string) "L-alanine-glycine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.44"^^xsd:string) "alanine--glyoxylate aminotransferase activity"^^xsd:string) AnnotationAssertion( "alanine-glyoxylate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.44"^^xsd:string) "alanine-glyoxylic aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.44"^^xsd:string) "AGT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.44"^^xsd:string) "Catalysis of the reaction: L-alanine + glyoxylate = pyruvate + glycine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.44"^^xsd:string) "L-alanine:glyoxylate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.145"^^xsd:string) "uridine diphosphoacetylglucosamine-glycopeptide beta-4-acetylglucosaminyltransferase IV activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.145"^^xsd:string) "uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase IV"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.145"^^xsd:string) "UDP-N-acetyl-D-glucosamine:3-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.145"^^xsd:string) "N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.145"^^xsd:string) "beta-acetylglucosaminyltransferase IV activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.145"^^xsd:string) "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.145"^^xsd:string) "N-acetylglucosaminyltransferase IV activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.145"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R."^^xsd:string) AnnotationAssertion( "alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.145"^^xsd:string) "GnTIV activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.143"^^xsd:string) "alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.143"^^xsd:string) "uridine diphosphoacetylglucosamine-alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.143"^^xsd:string) "acetylglucosaminyltransferase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.143"^^xsd:string) "uridine diphosphoacetylglucosamine-alpha-D-mannoside beta(1,2)-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.143"^^xsd:string) "UDP-N-acetyl-D-glucosamine:6-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.143"^^xsd:string) "uridine diphosphoacetylglucosamine-alpha-D-mannoside beta-1,2-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.143"^^xsd:string) "alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.143"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.143"^^xsd:string) "uridine diphosphoacetylglucosamine-mannoside alpha(1,6)-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.143"^^xsd:string) "UDP-GlcNAc:mannoside alpha-(1,6) acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.143"^^xsd:string) "UDP-GlcNAc:mannoside alpha-1,6 acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.143"^^xsd:string) "N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.143"^^xsd:string) "uridine diphosphoacetylglucosamine-mannoside alpha-1,6-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.143"^^xsd:string) "GnTII activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.143"^^xsd:string) "N-acetylglucosaminyltransferase II activity"^^xsd:string) AnnotationAssertion( "alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.49"^^xsd:string) "N-acetyl-alpha-galactosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.49"^^xsd:string) "alpha-NAGA activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.49"^^xsd:string) "alpha-galactosidase B activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.49"^^xsd:string) "alpha-N-acetyl-D-galactosaminide N-acetylgalactosaminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.49"^^xsd:string) "Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-alpha-D-galactosaminides."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.49"^^xsd:string) "N-acetyl-alpha-D-galactosaminidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-N-acetylgalactosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.49"^^xsd:string) "alpha-acetylgalactosaminidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.163"^^xsd:string) "uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->3-acetylglucosaminyltransferase"^^xsd:string) AnnotationAssertion(rdfs:label "beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.163"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.163"^^xsd:string) "UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.163"^^xsd:string) "poly-N-acetyllactosamine extension enzyme activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.137"^^xsd:string) "overt mitochondrial carnitine palmitoyltransferase"^^xsd:string) AnnotationAssertion(rdfs:label "carnitine O-octanoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.137"^^xsd:string) "medium-chain/long-chain carnitine acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.137"^^xsd:string) Annotation( "RHEA:17180"^^xsd:string) "Catalysis of the reaction: (R)-carnitine + octanoyl-CoA = (S)-octanoylcarnitine + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.137"^^xsd:string) "easily solubilized mitochondrial carnitine palmitoyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.137"^^xsd:string) "octanoyl-CoA:L-carnitine O-octanoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.137"^^xsd:string) "carnitine medium-chain acyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.17"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.17"^^xsd:string) "chondroitin 6-O-sulfotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "chondroitin 6-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.17"^^xsd:string) "3'-phosphoadenylyl-sulfate:chondroitin 6'-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.17"^^xsd:string) "3'-phosphoadenosine 5'-phosphosulfate (PAPS):chondroitin sulfate sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.17"^^xsd:string) "terminal 6-sulfotransferase activity"^^xsd:string) AnnotationAssertion( "chondroitin 6-sulphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.46"^^xsd:string) "dTDPglucose 4,6-hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.46"^^xsd:string) Annotation( "RHEA:17224"^^xsd:string) "Catalysis of the reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.46"^^xsd:string) "dTDP-glucose 4,6-hydro-lyase (dTDP-4-dehydro-6-deoxy-D-glucose-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.46"^^xsd:string) "dTDP-glucose 4,6-hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.46"^^xsd:string) "dTDPglucose 4,6-dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.46"^^xsd:string) "thymidine diphosphoglucose oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dTDP-glucose 4,6-dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.46"^^xsd:string) "TDP-glucose oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "formylmethionine deformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.31"^^xsd:string) "N-formyl-L-methionine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.31"^^xsd:string) Annotation( "RHEA:17784"^^xsd:string) "Catalysis of the reaction: N-formyl-L-methionine + H(2)O = L-methionine + formate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.29"^^xsd:string) "Catalysis of the reaction: (R)-glycerate + NAD+ = hydroxypyruvate + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.29"^^xsd:string) "hydroxypyruvate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycerate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.186"^^xsd:string) "priming glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "alpha-1,4-glucan-protein synthase (UDP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.186"^^xsd:string) "glycogenin activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.186"^^xsd:string) "Catalysis of the reaction: UDP-glucose + glycogenin = UDP + glucosylglycogenin."^^xsd:string) AnnotationAssertion(rdfs:label "glycogenin glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "1,4alpha-glucan-protein synthase (UDP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.186"^^xsd:string) "UDP-glucose:glycogenin glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.186"^^xsd:string) "UDP-alpha-D-glucose:glycogenin alpha-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.23"^^xsd:string) "3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.23"^^xsd:string) "3-OST-1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.23"^^xsd:string) "isoform/isozyme 1 (3-OST-1, HS3ST1)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.23"^^xsd:string) "heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.23"^^xsd:string) "glucosaminyl 3-O-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.23"^^xsd:string) "3'-phosphoadenylyl-sulfate:heparin-glucosamine 3-O-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.23"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. The [heparan sulfate]-glucosamine 3-sulfate has a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S."^^xsd:string) AnnotationAssertion( "heparin-glucosamine 3-O-sulfotransferase activity"^^xsd:string) AnnotationAssertion( "heparin-glucosamine 3-O-sulphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.125"^^xsd:string) "S-adenosyl-L-methionine:histone-arginine nomega-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "histone-arginine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.125"^^xsd:string) "S-adenosyl-L-methionine:histone-arginine omega-N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.125"^^xsd:string) "nuclear protein (histone) N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histone-arginine N-methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.125"^^xsd:string) "histone protein methylase I"^^xsd:string) AnnotationAssertion( "histone methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.125"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-arginine = S-adenosyl-L-homocysteine + (histone)-N-methyl-arginine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.125"^^xsd:string) "protein methylase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.125"^^xsd:string) "histone protein methylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.99.10"^^xsd:string) "isovaleroyl-coenzyme A dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "isovaleryl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.10"^^xsd:string) "Catalysis of the reaction: 3-methylbutanoyl-CoA + ETF = 3-methylbut-2-enoyl-CoA + reduced ETF."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.10"^^xsd:string) "3-methylbutanoyl-CoA:(acceptor) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.10"^^xsd:string) "isovaleryl-coenzyme A dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.10"^^xsd:string) "3-methylbutanoyl-CoA:acceptor oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.1.12"^^xsd:string) "L-ornithine ammonia-lyase (cyclizing; L-proline-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "ornithine cyclodeaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.12"^^xsd:string) Annotation( "RHEA:24371"^^xsd:string) "Catalysis of the reaction: L-ornithine = L-proline + NH(4)(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.12"^^xsd:string) "L-ornithine ammonia-lyase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.12"^^xsd:string) "OCD activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.12"^^xsd:string) "ornithine cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.12"^^xsd:string) "ornithine cyclase (deaminating) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "palmitoyl-protein thioesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.22"^^xsd:string) "palmitoyl-[protein] hydrolase"^^xsd:string) AnnotationAssertion( "palmitoyl-protein hydrolase activity"^^xsd:string) AnnotationAssertion( "palmitoyl-protein thiolesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.22"^^xsd:string) "Catalysis of the reaction: palmitoyl-protein + H2O = palmitate + protein."^^xsd:string) AnnotationAssertion(rdfs:label "palmitoyl-(protein) hydrolase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.4"^^xsd:string) "procollagen-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "procollagen-lysine 5-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.4"^^xsd:string) "lysylprotocollagen dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.4"^^xsd:string) "procollagen-lysine,2-oxoglutarate 5-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.4"^^xsd:string) "protocollagen lysyl hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.4"^^xsd:string) "lysine,2-oxoglutarate 5-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.4"^^xsd:string) "Catalysis of the reaction: procollagen L-lysine + 2-oxoglutarate + O2 = procollagen 5-hydroxy-L-lysine + succinate + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.4"^^xsd:string) "protocollagen lysine hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.4"^^xsd:string) "lysine-2-oxoglutarate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.4"^^xsd:string) "protocollagen lysine dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.4"^^xsd:string) "lysine hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.4"^^xsd:string) "lysyl hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.4"^^xsd:string) "collagen lysine hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein-tyrosine sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.20"^^xsd:string) "3'-phosphoadenylyl-sulfate:protein-tyrosine O-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.20"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate."^^xsd:string) AnnotationAssertion( "protein-tyrosine sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.20"^^xsd:string) "tyrosylprotein sulfotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.1"^^xsd:string) "nucleoside hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.1"^^xsd:string) "purine beta-ribosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.1"^^xsd:string) "nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.1"^^xsd:string) "N-ribosyl purine ribohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.1"^^xsd:string) "Catalysis of the reaction: a N-D-ribosylpurine + H2O = a purine + D-ribose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.1"^^xsd:string) "IAG-nucleoside hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.1"^^xsd:string) "purine-specific nucleoside N-ribohydrolase activity"^^xsd:string) AnnotationAssertion( "purine nucleosidase reaction"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.1"^^xsd:string) "inosine-adenosine-guanosine preferring nucleoside hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.1"^^xsd:string) "purine ribonucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.1"^^xsd:string) "ribonucleoside hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.1"^^xsd:string) "N-D-ribosylpurine ribohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.1"^^xsd:string) "purine-nucleoside ribohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.1"^^xsd:string) "IAG-NH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.1"^^xsd:string) "nucleosidase g activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.1"^^xsd:string) "purine nucleoside hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "purine nucleosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.35"^^xsd:string) "pyridoxine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.35"^^xsd:string) "pyridoxal phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.35"^^xsd:string) "pyridoxamine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.35"^^xsd:string) "Catalysis of the reaction: ATP + pyridoxal = ADP + pyridoxal 5'-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.35"^^xsd:string) "vitamin B(6) kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.35"^^xsd:string) "pyridoxal 5-phosphate-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.35"^^xsd:string) "vitamin B6 kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.35"^^xsd:string) "pyridoxal kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "pyridoxal kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.35"^^xsd:string) "ATP:pyridoxal 5'-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.29"^^xsd:string) "tRNA guanine transglycosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.29"^^xsd:string) "Catalysis of the reaction: tRNA guanine + queuine = tRNA queuine + guanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.29"^^xsd:string) "guanine insertion enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.29"^^xsd:string) "tRNA-guanine transglycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.29"^^xsd:string) "transfer ribonucleate glycosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.29"^^xsd:string) "guanine, queuine-tRNA transglycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.29"^^xsd:string) "tRNA transglycosylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "queuine tRNA-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.29"^^xsd:string) "Q-insertase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.29"^^xsd:string) "[tRNA]-guanine:queuine tRNA-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.29"^^xsd:string) "queuine transfer ribonucleate ribosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.8.3"^^xsd:string) "sarcosine:(acceptor) oxidoreductase (demethylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.8.3"^^xsd:string) "sarcosine:acceptor oxidoreductase (demethylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.8.3"^^xsd:string) "sarcosine N-demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.8.3"^^xsd:string) Annotation( "RHEA:19796"^^xsd:string) "Catalysis of the reaction: sarcosine + H2O + electron-transfer flavoprotein = glycine + formaldehyde + reduced electron-transfer flavoprotein."^^xsd:string) AnnotationAssertion(rdfs:label "sarcosine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.8.3"^^xsd:string) "monomethylglycine dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.91"^^xsd:string) "sphingosine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.91"^^xsd:string) "dihydrosphingosine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.91"^^xsd:string) "dihydrosphingosine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.91"^^xsd:string) "Catalysis of the reaction: ATP + sphinganine = ADP + sphinganine 1-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "sphinganine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.91"^^xsd:string) "ATP:sphinganine 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion( "sphingosine kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sulphite oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.3.1"^^xsd:string) Annotation( "RHEA:24603"^^xsd:string) "Catalysis of the reaction: H(2)O + O(2) + sulfite = H(2)O(2) + H(+) + sulfate."^^xsd:string) AnnotationAssertion(rdfs:label "sulfite oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.3.1"^^xsd:string) "sulfite:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid."^^xsd:string) AnnotationAssertion(rdfs:label "transaminase activity"^^xsd:string) AnnotationAssertion( "aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sulphuric ester hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfuric ester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: RSO-R' + H2O = RSOOH + R'H. This reaction is the hydrolysis of any sulfuric ester bond, any ester formed from sulfuric acid, O=SO(OH)2."^^xsd:string) AnnotationAssertion( "sulfatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.52"^^xsd:string) "Catalysis of the reaction: diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "diphosphoinositol-polyphosphate diphosphatase activity"^^xsd:string) AnnotationAssertion( "diphosphoinositol polyphosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.52"^^xsd:string) "diphosphoinositol-polyphosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.52"^^xsd:string) "diphospho-myo-inositol-polyphosphate diphosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.52"^^xsd:string) "DIPP activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "gamma-glutamyl carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18374194"^^xsd:string) "Catalysis of the reaction: peptidyl-glutamate + reduced vitamin K + CO2 + O2 = peptidyl-gamma-carboxyglutamate + vitamin K epoxide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "LacCer synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "UDP-galactose glucosylceramide beta-1,4-galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "lactosylceramide synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10764"^^xsd:string) Annotation( "PMID:9593693"^^xsd:string) "Catalysis of the reaction: UDP-D-galactose + a glucosylceramide = a lactosylceramide + uridine-5'-diphosphate. The glucosylceramide has sphinganine as the long chain base."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of arsenite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport."^^xsd:string) AnnotationAssertion( "arsenite porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "arsenite secondary active transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:27902"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Enables the directed movement of tetracycline into, out of or within a cell, or between cells. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles)."^^xsd:string) AnnotationAssertion(rdfs:label "tetracycline transporter activity"^^xsd:string) AnnotationAssertion( "tetracyclin transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "translation activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Any of a group of soluble proteins functioning in the activation of ribosome-mediated translation of mRNA into a polypeptide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protoheme IX farnesyltransferase activity"^^xsd:string) AnnotationAssertion( "heme O synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9177788"^^xsd:string) "heme A:farnesyltransferase activity"^^xsd:string) AnnotationAssertion( "haem O synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:HEMEOSYN-RXN"^^xsd:string) "Catalysis of the reaction: protoheme IX + (2E,6E)-farnesyl diphosphate + H2O = heme o + diphosphate."^^xsd:string) AnnotationAssertion( "protohaem IX farnesyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.101"^^xsd:string) "1,6-beta-D-mannan mannanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.101"^^xsd:string) "Catalysis of the random hydrolysis of (1->6)-alpha-D-mannosidic linkages in unbranched (1->6)-mannans."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.101"^^xsd:string) "1,6-alpha-D-mannan mannanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.101"^^xsd:string) "endo-1,6-beta-mannanase activity"^^xsd:string) AnnotationAssertion( "endo-alpha-D-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.101"^^xsd:string) "endo-alpha-1->6-D-mannanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.101"^^xsd:string) "mannan endo-1,6-beta-mannosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannan endo-1,6-alpha-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.101"^^xsd:string) "exo-1,6-beta-mannanase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10212226"^^xsd:string) "Catalysis of the reaction: UDP-galactose + N-acetylglucosamine = galactose-beta-1,3-N-acetylglucosamine + UDP."^^xsd:string) AnnotationAssertion( "beta3Gal-Ts activity"^^xsd:string) AnnotationAssertion( "UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "beta-1,3-GalTase activity"^^xsd:string) AnnotationAssertion( "UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "melatonin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Combining with benzodiazepines, a class of drugs with hypnotic, anxiolytic, anticonvulsive, amnestic and myorelaxant properties, to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "benzodiazepine receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "monoamine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:25375"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of the membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sucrose:proton symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "sucrose:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.5.3"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + H+(out) = sucrose(in) + H+(in)."^^xsd:string) AnnotationAssertion( "hydrogen/sucrose transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sodium:iodide symporter activity"^^xsd:string) AnnotationAssertion( "sodium/iodide symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.21.5.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: iodide(out) + Na+(out) = iodide(in) + Na+(in)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sodium/bile acid symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "bile acid:sodium symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.28.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(out) + Na+(out) = bile acid(in) + Na+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dgf"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a negatively charged ion from one side of a membrane to the other."^^xsd:string) AnnotationAssertion( "anion transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "anion transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sodium:bicarbonate cotransporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "sodium:bicarbonate symporter activity"^^xsd:string) AnnotationAssertion( "sodium/bicarbonate cotransporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.31.2.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sodium/potassium/chloride symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.30.1.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + K+(out) + Cl-(out) = Na+(in) + K+(in) + Cl-(in)."^^xsd:string) AnnotationAssertion(rdfs:label "sodium:potassium:chloride symporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.53.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in)."^^xsd:string) AnnotationAssertion( "sulphate:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfate:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "sulfate/hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "sulfate:proton symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "polyspecific organic cation transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "organic cation porter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "Catalysis of the transfer of organic cations from one side of the membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction."^^xsd:string) AnnotationAssertion(rdfs:label "secondary active organic cation transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "organic anion transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sucrose permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of sucrose from one side of the membrane to the other. Sucrose is the disaccharide O-beta-D-fructofuranosyl-(2->1)-alpha-D-glucopyranoside, a sweet-tasting, non-reducing sugar isolated industrially from sugar beet or sugar cane."^^xsd:string) AnnotationAssertion( "sucrose permease (PTS) activity"^^xsd:string) AnnotationAssertion(rdfs:label "sucrose transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hexose uniporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.1.5"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) = hexose(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "folate transporter activity"^^xsd:string) AnnotationAssertion( "vitamin M transporter activity"^^xsd:string) AnnotationAssertion( "vitamin B9 transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines."^^xsd:string) AnnotationAssertion(rdfs:label "folic acid transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "reduced folate transporter"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of reduced folate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport."^^xsd:string) AnnotationAssertion(rdfs:label "reduced folate carrier activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals."^^xsd:string) AnnotationAssertion(rdfs:label "ammonium transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.40.6.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ascorbate(out) + Na+(out) = ascorbate(in) + Na+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "L-ascorbate:sodium symporter activity"^^xsd:string) AnnotationAssertion( "sodium-dependent L-ascorbic acid transporter"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of acetyl-CoA into, out of or within a cell, or between cells. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis."^^xsd:string) AnnotationAssertion(rdfs:label "acetyl-CoA transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.21.5.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: multivitamin(out) + Na+(out) = multivitamin(in) + Na+(in). Multivitamins include pantothenate, biotin and lipoate."^^xsd:string) AnnotationAssertion(rdfs:label "sodium-dependent multivitamin transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.1.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + phosphate(in) = glucose 6-phosphate(in) + phosphate(out)."^^xsd:string) AnnotationAssertion(rdfs:label "glucose 6-phosphate:phosphate antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "phosphatidylcholine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of phosphatidylcholine into, out of or within a cell, or between cells. Phosphatidylcholine refers to a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylcholine transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of phosphatidylinositol into, out of or within a cell, or between cells. Phosphatidylinositol refers to any glycophospholipids with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol."^^xsd:string) AnnotationAssertion( "phosphatidylinositol transfer"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "taste receptor activity"^^xsd:string) AnnotationAssertion( "gustatory receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "Combining with soluble compounds to initiate a change in cell activity. These receptors are responsible for the sense of taste."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "G protein coupled peptide receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled peptide receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "peptide receptor activity, G-protein coupled"^^xsd:string) AnnotationAssertion( "peptide receptor activity, G protein coupled"^^xsd:string) AnnotationAssertion( "G-protein-coupled peptide receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.26"^^xsd:string) "FK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.26"^^xsd:string) "riboflavin kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "riboflavin kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.26"^^xsd:string) Annotation( "RHEA:14360"^^xsd:string) "Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.26"^^xsd:string) "flavokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.26"^^xsd:string) "riboflavine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.26"^^xsd:string) "ATP:riboflavin 5'-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.149"^^xsd:string) "UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-glucosamine beta-1,3-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.149"^^xsd:string) "UDP-GlcNAc:Galbeta-(1,4)-GlcNAcbeta-r-beta-(1,3)-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.149"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.149"^^xsd:string) "galbeta1->4GlcNAc-R beta1->3 N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.149"^^xsd:string) "poly-N-acetyllactosamine extension enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.149"^^xsd:string) "uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->3-acetylglucosaminyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.149"^^xsd:string) "uridine diphosphoacetylglucosamine-acetyllactosaminide beta-1,3-acetylglucosaminyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.149"^^xsd:string) "N-acetyllactosamine beta(1,3)N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.149"^^xsd:string) "GnTE activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.149"^^xsd:string) "UDP-GlcNAc:Galbeta-1,4-GlcNAcbeta-beta-1,3-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.149"^^xsd:string) "UDP-GlcNAc:GalR, beta-D-3-N-acetylglucosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.23"^^xsd:string) "Fapy-DNA glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.23"^^xsd:string) "Fpg protein"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.23"^^xsd:string) "2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase activity"^^xsd:string) AnnotationAssertion( "purine-specific oxidized base lesion DNA N-glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.23"^^xsd:string) "deoxyribonucleate glycosidase activity"^^xsd:string) AnnotationAssertion( "8-oxoguanine DNA glycosylase activity"^^xsd:string) AnnotationAssertion( "bifunctional DNA glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "oxidized purine base lesion DNA N-glycosylase activity"^^xsd:string) AnnotationAssertion( "DNA-formamidopyrimidine glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.23"^^xsd:string) "DNA glycohydrolase [2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimide releasing]"^^xsd:string) AnnotationAssertion( "DNA glycosylase/AP-lyase activity"^^xsd:string) AnnotationAssertion( "formamidopyrimidine-DNA glycosylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oxidized purine nucleobase lesion DNA N-glycosylase activity"^^xsd:string) AnnotationAssertion( "DNA glycosylase/beta-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.23"^^xsd:string) "2,6-diamino-4-hydroxy-5(N-methyl)formamidopyrimidine-DNA glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:11554296"^^xsd:string) "Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:rn"^^xsd:string) Annotation( "PMID:12787777"^^xsd:string) Annotation( "PMID:14726649"^^xsd:string) "Interacting selectively and non-covalently with Ran, a conserved Ras-like GTP-binding protein, implicated in nucleocytoplasmic transport, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly."^^xsd:string) AnnotationAssertion( "Ran-binding protein"^^xsd:string) AnnotationAssertion( "Ran protein binding"^^xsd:string) AnnotationAssertion(rdfs:label "Ran GTPase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:11057897"^^xsd:string) Annotation( "PMID:11790549"^^xsd:string) "Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase."^^xsd:string) AnnotationAssertion(rdfs:label "JUN kinase kinase activity"^^xsd:string) AnnotationAssertion( "JNKK"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.3"^^xsd:string) "Cd(2+)-exporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.3"^^xsd:string) "cadmium-translocating P-type ATPase activity"^^xsd:string) AnnotationAssertion( "cadmium exporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.3"^^xsd:string) "ATP phosphohydrolase (Cd2+-exporting)"^^xsd:string) AnnotationAssertion(rdfs:label "cadmium-exporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.3"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd2+(in) -> ADP + phosphate + Cd2+(out)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.3"^^xsd:string) "Cd2+-exporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.6"^^xsd:string) "ATP phosphohydrolase (H+-exporting)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.6"^^xsd:string) "H(+)-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "hydrogen exporting ATPase activity, phosphorylative mechanism"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.6"^^xsd:string) "H(+)-exporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.6"^^xsd:string) "H+-exporting ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydrogen-exporting ATPase activity, phosphorylative mechanism"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.6"^^xsd:string) "proton-translocating ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.6"^^xsd:string) "proton transport ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.6"^^xsd:string) "Catalysis of the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.6"^^xsd:string) "proton-translocating P-type ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.6"^^xsd:string) "H+-transporting ATPase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.6"^^xsd:string) "yeast plasma membrane ATPase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.6"^^xsd:string) "proton-exporting ATPase"^^xsd:string) AnnotationAssertion( "hydrogen-/sodium-translocating ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.6"^^xsd:string) "yeast plasma membrane H+-ATPase"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.7"^^xsd:string) "Na(+)-exporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.7"^^xsd:string) "sodium-exporting ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sodium-exporting ATPase activity, phosphorylative mechanism"^^xsd:string) AnnotationAssertion( "sodium exporting ATPase activity, phosphorylative mechanism"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.7"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) -> ADP + phosphate + Na+(out); by a phosphorylative mechanism."^^xsd:string) AnnotationAssertion( "hydrogen-/sodium-translocating ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.7"^^xsd:string) "ATP phosphohydrolase (Na+-exporting)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.7"^^xsd:string) "Na+-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.7"^^xsd:string) "Na+-exporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.7"^^xsd:string) "sodium transport ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.7"^^xsd:string) "Na(+)-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.7"^^xsd:string) "sodium-translocating P-type ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chloride-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.11"^^xsd:string) "Cl--transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.11"^^xsd:string) "chloride-motive ATPase activity"^^xsd:string) AnnotationAssertion( "chloride ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.11"^^xsd:string) "Cl--translocating ATPase activity"^^xsd:string) AnnotationAssertion( "chloride transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.11"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cl-(out) = ADP + phosphate + Cl-(in)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.11"^^xsd:string) "Cl--motive ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.11"^^xsd:string) "ATP phosphohydrolase (Cl--importing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.11"^^xsd:string) "Cl(-)-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.11"^^xsd:string) "chloride-translocating ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "potassium-uptake-ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.12"^^xsd:string) "potassium-importing ATPase activity"^^xsd:string) AnnotationAssertion( "potassium ABC transporter"^^xsd:string) AnnotationAssertion( "K+-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.12"^^xsd:string) "K+-translocating Kdp-ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.12"^^xsd:string) "k+-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.12"^^xsd:string) "ATP phosphohydrolase (K+-importing)"^^xsd:string) AnnotationAssertion( "potassium transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.12"^^xsd:string) "K(+)-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.12"^^xsd:string) "multi-subunit K+-transport ATPase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.12"^^xsd:string) "K+-importing ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.12"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "potassium-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.12"^^xsd:string) "K(+)-importing ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "guanine-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.37"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + guanine(out) = ADP + phosphate + guanine(in)."^^xsd:string) AnnotationAssertion( "guanine ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.37"^^xsd:string) "ATP phosphohydrolase (guanine-importing)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "steroid-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "xenobiotic ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.44"^^xsd:string) "PDR protein"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.44"^^xsd:string) "Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out)."^^xsd:string) AnnotationAssertion( "multidrug-resistance protein"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.44"^^xsd:string) "pleiotropic-drug-resistance protein"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.44"^^xsd:string) "ATP phosphohydrolase (steroid-exporting)"^^xsd:string) AnnotationAssertion( "multidrug resistance exporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.44"^^xsd:string) "MDR protein"^^xsd:string) AnnotationAssertion( "P-glycoprotein"^^xsd:string) AnnotationAssertion(rdfs:label "xenobiotic-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "steroid ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.44"^^xsd:string) "ATP phosphohydrolase (xenobiotic-exporting)"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.50"^^xsd:string) "ATP phosphohydrolase (protein-secreting)"^^xsd:string) AnnotationAssertion(rdfs:label "protein-exporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.50"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins."^^xsd:string) AnnotationAssertion( "protein-secreting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "enzyme transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein transporter activity"^^xsd:string) AnnotationAssertion( "secretin"^^xsd:string) AnnotationAssertion( "protein carrier activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of proteins into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion( "holin"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "protein transport chaperone"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.51"^^xsd:string) "ATP phosphohydrolase (mitochondrial protein-importing) activity"^^xsd:string) AnnotationAssertion(rdfs:label "mitochondrial protein-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.51"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.4.3"^^xsd:string) "ATP phosphohydrolase (tubulin-dimerizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.4.3"^^xsd:string) Annotation( "PMID:10910766"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the severing of a microtubule at a specific spot along its length, coupled to the hydrolysis of ATP."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.4.3"^^xsd:string) "katanin activity"^^xsd:string) AnnotationAssertion(rdfs:label "microtubule-severing ATPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.4.5"^^xsd:string) "kinesin ATP phosphohydrolase (minus-end-directed)"^^xsd:string) AnnotationAssertion(rdfs:label "minus-end-directed microtubule motor activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.4.5"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of movement along a microtubule toward the minus end, coupled to the hydrolysis of ATP (or GTP)."^^xsd:string) AnnotationAssertion( "minus-end-directed kinesin ATPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "plus-end-directed microtubule motor activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.4.4"^^xsd:string) "kinesin activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.4.4"^^xsd:string) "kinesin ATP phosphohydrolase (plus-end-directed)"^^xsd:string) AnnotationAssertion( "plus-end-directed kinesin ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.4.4"^^xsd:string) "Catalysis of movement along a microtubule toward the plus end, coupled to the hydrolysis of ATP (or GTP)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "JUN kinase phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: JUN kinase serine/threonine/tyrosine phosphate + H2O = JUN kinase serine/threonine/tyrosine + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Modulation of the activity of the enzyme calcium-dependent protein serine/threonine phosphatase."^^xsd:string) AnnotationAssertion(rdfs:label "calcium-dependent protein serine/threonine phosphatase regulator activity"^^xsd:string) AnnotationAssertion( "calcium-dependent protein serine/threonine phosphatase, intrinsic regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Modulation of the activity of the enzyme protein phosphatase type 1."^^xsd:string) AnnotationAssertion(rdfs:label "protein phosphatase type 1 regulator activity"^^xsd:string) AnnotationAssertion( "protein phosphatase type 1, intrinsic regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Modulation of the activity of the enzyme protein phosphatase type 2A."^^xsd:string) AnnotationAssertion(rdfs:label "protein phosphatase type 2A regulator activity"^^xsd:string) AnnotationAssertion( "protein phosphatase type 2A, intrinsic regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "cyclic AMP-dependent protein kinase regulator activity"^^xsd:string) AnnotationAssertion( "adenosine 3',5'-cyclophosphate-dependent protein kinase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Modulation of the activity of the enzyme cAMP-dependent protein kinase."^^xsd:string) AnnotationAssertion( "3',5'-cAMP-dependent protein kinase regulator activity"^^xsd:string) AnnotationAssertion(rdfs:label "cAMP-dependent protein kinase regulator activity"^^xsd:string) AnnotationAssertion( "cAMP-dependent protein kinase, intrinsic regulator activity"^^xsd:string) AnnotationAssertion( "3',5' cAMP-dependent protein kinase regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphorylase kinase regulator activity"^^xsd:string) AnnotationAssertion( "phosphorylase kinase, intrinsic regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.19"^^xsd:string) "Modulation of the activity of the enzyme phosphorylase kinase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.26"^^xsd:string) "alkyldihydroxyacetonephosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.26"^^xsd:string) "alkyl-DHAP"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.26"^^xsd:string) "alkyl-DHAP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.26"^^xsd:string) "dihydroxyacetone-phosphate acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.26"^^xsd:string) "Catalysis of the reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain acid anion."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.26"^^xsd:string) "alkyl DHAP synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.26"^^xsd:string) "1-acyl-glycerone-3-phosphate:long-chain-alcohol O-3-phospho-2-oxopropanyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.26"^^xsd:string) "alkyldihydroxyacetone phosphate synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alkylglycerone-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.26"^^xsd:string) "DHAP-AT"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "diuretic hormone activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "InterPro:IPR003621"^^xsd:string) Annotation( "PMID:8618894"^^xsd:string) "The action characteristic of a diuretic hormone, any peptide hormone that, upon receptor binding, regulates water balance and fluid secretion."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond."^^xsd:string) AnnotationAssertion( "ubiquitin-like activating enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "small protein activating enzyme activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "rRNA methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methyluridine."^^xsd:string) AnnotationAssertion(rdfs:label "rRNA (uridine-2'-O-)-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mtg_apoptosis"^^xsd:string) "Increases the rate of proteolysis catalyzed by a cysteine-type endopeptidase involved in the apoptotic process."^^xsd:string) AnnotationAssertion( "caspase activator activity"^^xsd:string) AnnotationAssertion(rdfs:label "cysteine-type endopeptidase activator activity involved in apoptotic process"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA topoisomerase (ATP-hydrolyzing) inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stops, prevents or reduces the activity of ATP-hydrolyzing DNA topoisomerase. ATP-hydrolyzing DNA topoisomerase catalyzes the DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2."^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "DNA gyrase inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with penicillin, any antibiotic that contains the condensed beta-lactamthiazolidine ring system."^^xsd:string) AnnotationAssertion(rdfs:label "penicillin binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.-"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: (3R)-3-hydroxytetradecanoyl-[acyl-carrier protein] = tetradecenoyl-[acyl-carrier protein] + H2O."^^xsd:string) AnnotationAssertion( "(3R)-hydroxymyristoyl-[acyl-carrier protein] dehydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity"^^xsd:string) AnnotationAssertion( "(3R)-hydroxymyristoyl-ACP dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.99.7"^^xsd:string) Annotation( "RHEA:16936"^^xsd:string) "Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + H(2)O = 2-oxobutanate + NH(4)(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.7"^^xsd:string) "ACC deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.7"^^xsd:string) "1-aminocyclopropane carboxylic acid deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.7"^^xsd:string) "1-aminocyclopropane-1-carboxylate aminohydrolase (isomerizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.7"^^xsd:string) "1-aminocyclopropane-1-carboxylate endolyase (deaminating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-aminocyclopropane-1-carboxylate deaminase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "1-deoxyxylulose-5-phosphate synthase activity"^^xsd:string) AnnotationAssertion( "DXP-synthase activity"^^xsd:string) AnnotationAssertion( "DOXP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.7"^^xsd:string) "pyruvate:D-glyceraldehyde-3-phosphate acetaldehydetransferase (decarboxylating)"^^xsd:string) AnnotationAssertion( "1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-deoxy-D-xylulose-5-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.7"^^xsd:string) Annotation( "RHEA:12608"^^xsd:string) "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO(2)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.56"^^xsd:string) "D-fructose-1-phosphate kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-phosphofructokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.56"^^xsd:string) "ATP:D-fructose-phosphate 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.56"^^xsd:string) "Catalysis of the reaction: ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.56"^^xsd:string) "phosphofructokinase 1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.56"^^xsd:string) "1-phosphofructokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.56"^^xsd:string) "fructose-1-phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.56"^^xsd:string) "fructose 1-phosphate kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.16"^^xsd:string) "cyclic phosphodiesterase:3'-nucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.16"^^xsd:string) "cyclic 2',3'-nucleotide 2'-phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.16"^^xsd:string) "2',3 '-cyclic AMP phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.16"^^xsd:string) "2',3'-cyclic nucleotide phosphohydrolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.16"^^xsd:string) "2',3'-cyclic nucleoside monophosphate phosphodiesterase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.16"^^xsd:string) "2',3'-cyclic nucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.16"^^xsd:string) "2':3'-cyclic nucleotide phosphodiesterase:3'-nucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.16"^^xsd:string) "ribonucleoside 2',3'-cyclic phosphate diesterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2',3'-cyclic-nucleotide 2'-phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.16"^^xsd:string) "Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.16"^^xsd:string) "nucleoside-2',3'-cyclic-phosphate 3'-nucleotidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.16"^^xsd:string) "cyclic 2',3'-nucleotide phosphodiesterase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.16"^^xsd:string) "2':3'-cyclic phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.16"^^xsd:string) "2',3'-cyclic AMP 2'-phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2'-5' RNA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:8940112"^^xsd:string) "Catalysis of the formation of a phosphodiester bond between the 2'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another."^^xsd:string) AnnotationAssertion(rdfs:label "2'-5'-RNA ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a phosphate group from one compound to the 2' position of another."^^xsd:string) AnnotationAssertion(rdfs:label "2'-phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19394346"^^xsd:string) "THDP N-succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.117"^^xsd:string) "tetrahydropicolinate succinylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.117"^^xsd:string) "tetrahydrodipicolinate N-succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.117"^^xsd:string) "tetrahydrodipicolinate succinylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.117"^^xsd:string) "tetrahydrodipicolinate succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.117"^^xsd:string) "succinyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.117"^^xsd:string) Annotation( "RHEA:17328"^^xsd:string) "Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + H(2)O + succinyl-CoA = L-2-succinylamino-6-oxopimelate + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.117"^^xsd:string) "succinyl-CoA:tetrahydrodipicolinate N-succinyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.117"^^xsd:string) "succinyl-CoA:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.28"^^xsd:string) "2,3-dihydro-2,3-dihydroxybenzoate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.28"^^xsd:string) Annotation( "RHEA:23827"^^xsd:string) "Catalysis of the reaction: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD(+) = 2,3-dihydroxybenzoate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.28"^^xsd:string) "2,3-DHB dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2,3-dihydroxybenzoate-AMP ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(2,3-dihydroxybenzoyl)adenylate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.58"^^xsd:string) Annotation( "RHEA:20232"^^xsd:string) "Catalysis of the reaction: 2,3-dihydroxybenzoate + ATP = 2,3-dihydroxybenzoyl 5'-adenylate + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.58"^^xsd:string) "ATP:2,3-dihydroxybenzoate adenylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.34"^^xsd:string) "4-enoyl-CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.34"^^xsd:string) "4-enoyl coenzyme A (reduced nicotinamide adenine dinucleotide phosphate) reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2,4-dienoyl-CoA reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.34"^^xsd:string) "trans-2,3-didehydroacyl-CoA:NADP+ 4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.34"^^xsd:string) "4-enoyl-CoA reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.34"^^xsd:string) "4-enoyl-CoA reductase (NADPH2)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.34"^^xsd:string) "Catalysis of the reaction: trans-2,3-didehydroacyl-CoA + NADP+ = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.58"^^xsd:string) "ATP:2-dehydro-3-deoxy-D-galactonate 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.58"^^xsd:string) "2-keto-3-deoxy-galactonokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.58"^^xsd:string) "2-keto-3-deoxygalactonate kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "2-dehydro-3-deoxygalactonokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.58"^^xsd:string) "2-oxo-3-deoxygalactonate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.58"^^xsd:string) "2-keto-3-deoxygalactonokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.58"^^xsd:string) Annotation( "RHEA:16528"^^xsd:string) "Catalysis of the reaction: 2-dehydro-3-deoxy-D-galactonate + ATP = 6-phospho-2-dehydro-3-deoxy-D-galactonate + ADP + 2 H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.20"^^xsd:string) "2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.20"^^xsd:string) "alpha-keto-beta-deoxy-D-glucarate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.20"^^xsd:string) "Catalysis of the reaction: 2-dehydro-3-deoxy-D-glucarate = pyruvate + tartronate semialdehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.20"^^xsd:string) "2-keto-3-deoxyglucarate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.20"^^xsd:string) "2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase (pyruvate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "2-dehydro-3-deoxyglucarate aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.45"^^xsd:string) "2-keto-3-deoxygluconokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.45"^^xsd:string) "2-keto-3-deoxygluconate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.45"^^xsd:string) "3-deoxy-2-oxo-D-gluconate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.45"^^xsd:string) "ATP:2-dehydro-3-deoxy-D-gluconate 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.45"^^xsd:string) "KDG kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.45"^^xsd:string) Annotation( "RHEA:14800"^^xsd:string) "Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.45"^^xsd:string) "2-keto-3-deoxygluconokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.45"^^xsd:string) "ketodeoxygluconokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.45"^^xsd:string) "2-keto-3-deoxy-D-gluconic acid kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-dehydro-3-deoxygluconokinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.21"^^xsd:string) "phospho-2-keto-3-deoxygalactonate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.21"^^xsd:string) "2-keto-3-deoxy-6-phosphogalactonic aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.21"^^xsd:string) "2-keto-3-deoxy-6-phosphogalactonic acid aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.21"^^xsd:string) Annotation( "RHEA:24467"^^xsd:string) "Catalysis of the reaction: 6-phospho-2-dehydro-3-deoxy-D-galactonate = D-glyceraldehyde 3-phosphate + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.21"^^xsd:string) "(KDPGal)aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.21"^^xsd:string) "2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.21"^^xsd:string) "2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.21"^^xsd:string) "6-phospho-2-dehydro-3-deoxygalactonate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.21"^^xsd:string) "6-phospho-2-keto-3-deoxygalactonate aldolase activity"^^xsd:string) AnnotationAssertion( "2-dehydro-3-deoxyphosphogalactonate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.21"^^xsd:string) "2-oxo-3-deoxygalactonate 6-phosphate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.21"^^xsd:string) "phospho-2-keto-3-deoxygalactonic aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.14"^^xsd:string) "2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.14"^^xsd:string) "phospho-2-keto-3-deoxygluconate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.14"^^xsd:string) "6-phospho-2-keto-3-deoxygluconate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.14"^^xsd:string) "KDPG aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.14"^^xsd:string) "2-keto-3-deoxy-6-phosphogluconic aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.14"^^xsd:string) "2-oxo-3-deoxy-6-phosphogluconate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.14"^^xsd:string) "Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate 6-phosphate = pyruvate + D-glyceraldehyde 3-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.14"^^xsd:string) "2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.14"^^xsd:string) "2-keto-3-deoxy-6-phosphogluconate aldolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-dehydro-3-deoxy-phosphogluconate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.14"^^xsd:string) "phospho-2-dehydro-3-deoxygluconate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.14"^^xsd:string) "2-keto-3-deoxygluconate-6-P-aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.14"^^xsd:string) "phospho-2-keto-3-deoxygluconic aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.14"^^xsd:string) "ODPG aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.14"^^xsd:string) "KDPG-aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.14"^^xsd:string) "2-keto-3-deoxygluconate-6-phosphate aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.55"^^xsd:string) "KDO-8-phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.55"^^xsd:string) "2-keto-3-deoxy-8-phosphooctonic synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.55"^^xsd:string) "3-deoxy-D-mannooctulosonate-8-phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.55"^^xsd:string) "phosphoenolpyruvate:D-arabinose-5-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.55"^^xsd:string) "KDOP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.55"^^xsd:string) "3-deoxy-D-manno-octulosonate-8-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.55"^^xsd:string) "phospho-2-keto-3-deoxyoctonate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.55"^^xsd:string) "2-dehydro-3-deoxy-phosphooctonate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.55"^^xsd:string) "KDO-8-P synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.55"^^xsd:string) "3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-deoxy-8-phosphooctulonate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.55"^^xsd:string) "2-dehydro-3-deoxy-D-octonate-8-phosphate D-arabinose-5-phosphate-lyase (pyruvate-phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.55"^^xsd:string) "3-deoxyoctulosonic 8-phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.55"^^xsd:string) Annotation( "RHEA:14056"^^xsd:string) "Catalysis of the reaction: D-arabinose 5-phosphate + H(2)O + phosphoenolpyruvate = 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion( "2-dehydro-3-deoxyphosphooctonate aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.169"^^xsd:string) Annotation( "RHEA:16236"^^xsd:string) "Catalysis of the reaction: (R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.169"^^xsd:string) "KPA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.169"^^xsd:string) "ketopantoic acid reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.169"^^xsd:string) "2-ketopantoic acid reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-dehydropantoate 2-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.169"^^xsd:string) "2-ketopantoate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.169"^^xsd:string) "(R)-pantoate:NADP+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.169"^^xsd:string) "ketopantoate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.169"^^xsd:string) "2-oxopantoate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.125"^^xsd:string) "2-deoxy-D-gluconate:NAD+ 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.125"^^xsd:string) "Catalysis of the reaction: 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.125"^^xsd:string) "2-keto-3-deoxygluconate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.125"^^xsd:string) "2-deoxygluconate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-deoxy-D-gluconate 3-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.60"^^xsd:string) "(R)-glycerate:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxy-3-oxopropionate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.60"^^xsd:string) "Catalysis of the reaction: (R)-glycerate + NADP+ = 2-hydroxy-3-oxopropanoate + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.60"^^xsd:string) "tartronate semialdehyde reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-octaprenyl-6-methoxyphenol hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:2-OCTAPRENYL-6-METHOXYPHENOL-HYDROX-RXN"^^xsd:string) "Catalysis of the reaction: 2-octaprenyl-6-methoxyphenol + O2 + 4 H+ = 2-octaprenyl-6-methoxy-1,4-benzoquinol + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN"^^xsd:string) "Catalysis of the reaction: 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone + O2 = 2-octoprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone."^^xsd:string) AnnotationAssertion(rdfs:label "2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.71"^^xsd:string) "2-oxoglutarate carboxy-lyase (succinate-semialdehyde-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.71"^^xsd:string) "pre-2-oxoglutarate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.71"^^xsd:string) "2-oxoglutarate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.71"^^xsd:string) "alpha-ketoglutaric decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.71"^^xsd:string) "alpha-ketoglutarate decarboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-oxoglutarate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.71"^^xsd:string) Annotation( "RHEA:10527"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + H(+) = CO(2) + succinate semialdehyde."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-oxopent-4-enoate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.80"^^xsd:string) "Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = 2-oxopent-4-enoate + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.80"^^xsd:string) "2-keto-4-pentenoate (vinylpyruvate)hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.80"^^xsd:string) "4-hydroxy-2-oxopentanoate hydro-lyase (2-oxopent-4-enoate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.80"^^xsd:string) "OEH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.80"^^xsd:string) "2-keto-4-pentenoate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.80"^^xsd:string) "4-hydroxy-2-oxopentanoate hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "MECP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.12"^^xsd:string) "2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing)"^^xsd:string) AnnotationAssertion(rdfs:label "2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.12"^^xsd:string) Annotation( "RHEA:23867"^^xsd:string) "Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.12"^^xsd:string) "MECDP-synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.12"^^xsd:string) "2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3,4-dihydroxy-2-butanone-4-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.12"^^xsd:string) Annotation( "RHEA:18460"^^xsd:string) "Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.15"^^xsd:string) "HPC dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.15"^^xsd:string) "3,4-dihydroxyphenylacetate:oxygen 2,3-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(rdfs:label "3,4-dihydroxyphenylacetate 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.15"^^xsd:string) "homoprotocatechuate 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.15"^^xsd:string) Annotation( "RHEA:15636"^^xsd:string) "Catalysis of the reaction: 3,4-dihydroxyphenylacetate + O(2) = 5-formyl-2-hydroxyhepta-2,4-dienedioate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.15"^^xsd:string) "3,4-dihydroxyphenylacetic acid 2,3-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:MHPHYDROXY-RXN"^^xsd:string) "Catalysis of the reaction: 3-(3-hydroxyphenyl)propionate + NADH + oxygen + H+ = 3-(2,3-dihydroxyphenyl)propionate + NAD+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "3-(3-hydroxyphenyl)propionate hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.64"^^xsd:string) "S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-9 = S-adenosyl-L-homocysteine + ubiquinone-9."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.64"^^xsd:string) "5-demethylubiquinone-9 methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.64"^^xsd:string) "OMHMB-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-demethylubiquinone-9 3-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.64"^^xsd:string) "S-adenosyl-L-methionine:2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone 3-O-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.38"^^xsd:string) "2-keto-3-deoxyoctonate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-deoxy-manno-octulosonate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.38"^^xsd:string) "cytidine monophospho-3-deoxy-D-manno-octulosonate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.38"^^xsd:string) "CMP-KDO synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.38"^^xsd:string) "CMP-3-deoxy-D-manno-octulosonate diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.38"^^xsd:string) "CMP-3-deoxy-D-manno-octulosonate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.38"^^xsd:string) "Catalysis of the reaction: CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.38"^^xsd:string) "CMP-3-deoxy-D-manno-octulosonate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.38"^^xsd:string) "CTP:3-deoxy-D-manno-octulosonate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.38"^^xsd:string) "CMP-2-keto-3-deoxyoctulosonic acid synthetase activity"^^xsd:string) AnnotationAssertion( "CTP:3-deoxy-manno-octulosonate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.38"^^xsd:string) "3-deoxy-D-manno-octulosonate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.38"^^xsd:string) "CTP:CMP-3-deoxy-D-manno-octulosonate cytidylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.157"^^xsd:string) "L-(+)-3-hydroxybutyryl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.157"^^xsd:string) "(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.157"^^xsd:string) "beta-hydroxybutyryl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.157"^^xsd:string) "BHBD activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.157"^^xsd:string) "beta-hydroxybutyryl coenzyme A dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxybutyryl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.157"^^xsd:string) "L(+)-3-hydroxybutyryl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.157"^^xsd:string) "Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.157"^^xsd:string) "dehydrogenase, L-3-hydroxybutyryl coenzyme A (nicotinamide adenine dinucleotide phosphate)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.2.3"^^xsd:string) "3-hydroxyacyl-CoA epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.2.3"^^xsd:string) "3-hydroxybutanoyl-CoA 3-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.2.3"^^xsd:string) "Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxybutyryl-CoA epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.2.3"^^xsd:string) "3-hydroxybutyryl coenzyme A epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.60"^^xsd:string) "D-3-hydroxydecanoyl-acyl-carrier-protein dehydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.60"^^xsd:string) "FabA"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.60"^^xsd:string) "Catalysis of the reaction: (3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2,3-decenoyl-[acyl-carrier protein] or 3,4-decenoyl-[acyl-carrier protein] + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.60"^^xsd:string) "HDDase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.60"^^xsd:string) "D-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.60"^^xsd:string) "beta-hydroxyacyl-ACP dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.60"^^xsd:string) "3-hydroxydecanoyl-acyl carrier protein dehydratase activity"^^xsd:string) AnnotationAssertion( "3-hydroxydecanoyl-ACP dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.60"^^xsd:string) "(3R)-3-hydroxydecanoyl-acyl-carrier-protein hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.60"^^xsd:string) "3-hydroxydecanoyl-acyl-carrier-protein dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.60"^^xsd:string) "3-hydroxydecanoyl-acyl carrier protein dehydrase activity"^^xsd:string) AnnotationAssertion( "3-hydroxydecanoyl-[acyl-carrier protein] dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.60"^^xsd:string) "beta-hydroxydecanoate dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.60"^^xsd:string) "beta-hydroxydecanoyl thioester dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.60"^^xsd:string) "beta-hydroxyacyl-acyl carrier protein dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.60"^^xsd:string) "beta-hydroxydecanoyl thiol ester dehydrase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "polyprenyl p-hydroxybenzoate decarboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:3-OCTAPRENYL-4-OHBENZOATE-DECARBOX-RXN"^^xsd:string) "Catalysis of the reaction: 3-octaprenyl-4-hydroxy benzoate = 2-octaprenylphenol + CO2."^^xsd:string) AnnotationAssertion( "3-polyprenyl 4-hydroxybenzoate decarboxylase activity"^^xsd:string) AnnotationAssertion( "UbiD"^^xsd:string) AnnotationAssertion( "3-polyprenyl-4-hydroxybenzoate carboxy-lyase activity"^^xsd:string) AnnotationAssertion( "PPHB decarboxylase activity"^^xsd:string) AnnotationAssertion( "UbiX"^^xsd:string) AnnotationAssertion( "3-octaprenyl-4-hydroxybenzoate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.12.19"^^xsd:string) "HcaA1A2CD"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0307"^^xsd:string) "Catalysis of the reaction: 3-phenylpropionate + NADH + H+ + O2 = NAD+ + cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.19"^^xsd:string) "3-phenylpropanoate dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-phenylpropionate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.19"^^xsd:string) "Hca dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.19"^^xsd:string) "3-phenylpropanoate,NADH:oxygen oxidoreductase (2,3-hydroxylating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "aminodeoxychorismate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.38"^^xsd:string) "ADC lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.38"^^xsd:string) "enzyme X activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.38"^^xsd:string) "4-amino-4-deoxychorismate pyruvate-lyase activity"^^xsd:string) AnnotationAssertion( "p-aminobenzoate synthetase"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.38"^^xsd:string) "4-amino-4-deoxychorismate pyruvate-lyase (4-aminobenzoate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "4-amino-4-deoxychorismate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.38"^^xsd:string) Annotation( "RHEA:16204"^^xsd:string) "Catalysis of the reaction: 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate."^^xsd:string) AnnotationAssertion( "para-aminobenzoic acid (PABA) synthase"^^xsd:string) AnnotationAssertion( "para-aminobenzoic acid synthase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.1.17"^^xsd:string) Annotation( "RHEA:23899"^^xsd:string) "Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.17"^^xsd:string) "5-keto-4-deoxyuronate isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.17"^^xsd:string) "4-deoxy-L-threo-5-hexulose uronate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.17"^^xsd:string) "4-deoxy-L-threo-5-hexosulose-uronate aldose-ketose-isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3.16"^^xsd:string) "DL-4-hydroxy-2-ketoglutarate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.16"^^xsd:string) "2-oxo-4-hydroxyglutaric aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.16"^^xsd:string) "4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.16"^^xsd:string) "KHG-aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.16"^^xsd:string) "2-keto-4-hydroxyglutaric aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.16"^^xsd:string) "4-hydroxy-2-ketoglutaric aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.16"^^xsd:string) "2-oxo-4-hydroxyglutarate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.16"^^xsd:string) "2-keto-4-hydroxybutyrate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.16"^^xsd:string) "Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.16"^^xsd:string) "4-hydroxy-2-ketoglutarate aldolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxy-2-oxoglutarate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.16"^^xsd:string) "hydroxyketoglutarate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.16"^^xsd:string) "2-keto-4-hydroxyglutarate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.16"^^xsd:string) "hydroxyketoglutaric aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.16"^^xsd:string) "4-hydroxy-2-oxoglutarate glyoxylate-lyase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3.39"^^xsd:string) "DmpG"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.39"^^xsd:string) "4-hydroxy-2-oxovalerate pyruvate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.39"^^xsd:string) "4-hydroxy-2-ketovalerate aldolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxy-2-oxovalerate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.39"^^xsd:string) "4-hydroxy-2-oxopentanoate pyruvate-lyase (acetaldehyde-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.39"^^xsd:string) "4-hydroxy-2-oxopentanoate pyruvate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.39"^^xsd:string) Annotation( "RHEA:22627"^^xsd:string) "Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = acetaldehyde + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.39"^^xsd:string) "HOA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "5-amino-6-(5'-phosphoribosylamino)uracil reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.193"^^xsd:string) Annotation( "RHEA:17848"^^xsd:string) "Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)uracil + NADP(+) = 5-amino-6-(5-phosphoribosylamino)uracil + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.193"^^xsd:string) "aminodioxyphosphoribosylaminopyrimidine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.193"^^xsd:string) "5-amino-6-(5-phosphoribitylamino)uracil:NADP+ 1'-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "5-amino-6-(5-phosphoribosylamino)uracil reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "HHDD isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.10"^^xsd:string) "5-carboxymethyl-2-hydroxymuconate delta2,Delta4-2-oxo,Delta3-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.10"^^xsd:string) "Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate = 5-carboxy-2-oxohept-3-enedioate."^^xsd:string) AnnotationAssertion(rdfs:label "5-carboxymethyl-2-hydroxymuconate delta-isomerase activity"^^xsd:string) AnnotationAssertion( "hpaG-1"^^xsd:string) AnnotationAssertion( "2-hydroxyhepta-2,4-diene-1,7-dioate isomerase"^^xsd:string) AnnotationAssertion( "5-carboxymethyl-2-hydroxymuconate D-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.10"^^xsd:string) "CHM isomerase activity"^^xsd:string) AnnotationAssertion( "hpaG1"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.10"^^xsd:string) "5-carboxymethyl-2-hydroxymuconic acid isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "methyltetrahydrofolate--homocysteine vitamin B12 methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "tetrahydropteroylglutamic methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "N(5)-methyltetrahydrofolate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "methionine synthase (cobalamin-dependent) activity"^^xsd:string) AnnotationAssertion(rdfs:label "methionine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "B12 N5-methyltetrahydrofolate homocysteine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "MetH"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "5-methyltetrahydrofolate--homocysteine S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "N(5)-methyltetrahydrofolic--homocysteine vitamin B12 transmethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "N5-methyltetrahydrofolate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "N(5)-methyltetrahydrofolate--homocysteine cobalamin methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) Annotation( "RHEA:11175"^^xsd:string) "Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "vitamin B12 methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "tetrahydrofolate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "5-methyltetrahydrofolate:L-homocysteine S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "5-methyltetrahydrofolate--homocysteine transmethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "tetrahydropteroylglutamate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "N5-methyltetrahydrofolic-homocysteine vitamin B12 transmethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "B12 N(5)-methyltetrahydrofolate homocysteine methyltransferase activity"^^xsd:string) AnnotationAssertion( "5-methyltetrahydrofolate-homocysteine S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "cobalamin-dependent methionine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "N-methyltetrahydrofolate:L-homocysteine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.13"^^xsd:string) "N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.86"^^xsd:string) "phospho-beta-glucosidase A"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.86"^^xsd:string) "Catalysis of the reaction: 6-phospho-beta-D-glucoside-(1,4)-D-glucose + H2O = D-glucose 6-phosphate + glucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.86"^^xsd:string) "6-phospho-beta-D-glucosyl-(1,4)-D-glucose glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.86"^^xsd:string) "phosphocellobiase activity"^^xsd:string) AnnotationAssertion(rdfs:label "6-phospho-beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.86"^^xsd:string) "phospho-beta-glucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.26"^^xsd:string) "phytate 6-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.26"^^xsd:string) "myo-inositol-hexakisphosphate 6-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.26"^^xsd:string) "Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = 1-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "4-phytase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.26"^^xsd:string) "6-phytase (name based on 1L-numbering system and not 1D-numbering)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.26"^^xsd:string) "phytase activity"^^xsd:string) AnnotationAssertion( "6-phytase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.159"^^xsd:string) "7-alpha-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.159"^^xsd:string) "7alpha-hydroxysteroid:NAD+ 7-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cholate 7-alpha-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.159"^^xsd:string) "7alpha-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.159"^^xsd:string) Annotation( "RHEA:19412"^^xsd:string) "Catalysis of the reaction: cholate + NAD(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.159"^^xsd:string) "7alpha-HSDH"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.159"^^xsd:string) "7alpha-hydroxy steroid dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.47"^^xsd:string) Annotation( "RHEA:20715"^^xsd:string) "Catalysis of the reaction: L-alanine + H(+) + pimelyl-CoA = 8-amino-7-oxononanoate + CO(2) + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.47"^^xsd:string) "7-keto-8-aminopelargonic synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.47"^^xsd:string) "8-amino-7-ketopelargonate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.47"^^xsd:string) "7-keto-8-amino-pelargonic acid synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "8-amino-7-oxononanoate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.47"^^xsd:string) "8-amino-7-oxopelargonate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.47"^^xsd:string) "7-keto-8-aminopelargonic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.47"^^xsd:string) "AONS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.47"^^xsd:string) "6-carboxyhexanoyl-CoA:L-alanine C-carboxyhexanoyltransferase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.47"^^xsd:string) "7-KAP synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.20"^^xsd:string) Annotation( "RHEA:17580"^^xsd:string) "Catalysis of the reaction: ADP-D-glycero-D-manno-heptose = ADP-L-glycero-D-manno-heptose."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.20"^^xsd:string) "ADP-L-glycero-D-manno-heptose 6-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.20"^^xsd:string) "ADPglyceromanno-heptose 6-epimerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ADP-glyceromanno-heptose 6-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:LIPA-CORESYN-PWY"^^xsd:string) "ADP-heptose:LPS heptosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ADP-heptose-lipopolysaccharide heptosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-5061"^^xsd:string) "Catalysis of the reaction: heptosyl-KDO2-lipid A + ADP-L-glycero-beta-D-manno-heptose = heptosyl2-KDO2-lipid A + ADP + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.4"^^xsd:string) "AMP phosphoribohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "AMP nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.4"^^xsd:string) Annotation( "RHEA:20132"^^xsd:string) "Catalysis of the reaction: AMP + H(2)O = D-ribose 5-phosphate + adenine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.4"^^xsd:string) "adenosine monophosphate nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.4"^^xsd:string) "adenylate nucleosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CDP-diacylglycerol diphosphatase activity"^^xsd:string) AnnotationAssertion( "CDP-diacylglycerol pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.26"^^xsd:string) "CDP diacylglycerol hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.26"^^xsd:string) "CDP-diacylglycerol phosphatidylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.26"^^xsd:string) "cytidine diphosphodiacylglycerol pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.26"^^xsd:string) Annotation( "RHEA:15224"^^xsd:string) "Catalysis of the reaction: CDP-diacylglycerol + H(2)O = a phosphatidate + CMP + 2 H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.4"^^xsd:string) "D-alanylalanine synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-alanine-D-alanine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.4"^^xsd:string) "alanylalanine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.4"^^xsd:string) Annotation( "RHEA:11227"^^xsd:string) "Catalysis of the reaction: 2 D-alanine + ATP = D-alanyl-D-alanine + ADP + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.4"^^xsd:string) "D-alanine:D-alanine ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.4"^^xsd:string) "alanine:alanine ligase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.4"^^xsd:string) "D-alanyl-D-alanine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.4"^^xsd:string) "D-Ala-D-Ala synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-amino-acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.99.1"^^xsd:string) "D-amino-acid:(acceptor) oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.99.1"^^xsd:string) "Catalysis of the reaction: a D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.99.1"^^xsd:string) "D-amino-acid:acceptor oxidoreductase (deaminating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:H2NTPEPIM-RXN"^^xsd:string) "Catalysis of the reaction: dihydroneopterin triphosphate = dihydromonapterin-triphosphate."^^xsd:string) AnnotationAssertion( "D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dihydroneopterin triphosphate 2'-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.28"^^xsd:string) "D-lactic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-lactate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.28"^^xsd:string) Annotation( "RHEA:16372"^^xsd:string) "Catalysis of the reaction: (R)-lactate + NAD(+) = H(+) + NADH + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.28"^^xsd:string) "D-lactic dehydrogenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.1.18"^^xsd:string) "D-serine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.18"^^xsd:string) "D-serine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.18"^^xsd:string) "D-serine ammonia-lyase (pyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.18"^^xsd:string) "D-serine dehydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-serine ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.18"^^xsd:string) "D-serine dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.18"^^xsd:string) "D-hydroxyaminoacid dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.18"^^xsd:string) "Catalysis of the reaction: D-serine = pyruvate + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.18"^^xsd:string) "D-hydroxy amino acid dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.18"^^xsd:string) "D-serine hydro-lyase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.18"^^xsd:string) "D-serine dehydratase (deaminating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.20"^^xsd:string) "deoxyribonucleate 3-methyladenine glycosidase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.20"^^xsd:string) Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:10872450"^^xsd:string) Annotation( "PMID:9224623"^^xsd:string) "Catalysis of the reaction: DNA containing 3-methyladenine + H2O = DNA with abasic site + 3-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methyladenine and the deoxyribose sugar to remove the 3-methyladenine, leaving an abasic site."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.20"^^xsd:string) "DNA-3-methyladenine glycosidase I activity"^^xsd:string) AnnotationAssertion(rdfs:label "DNA-3-methyladenine glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.20"^^xsd:string) "alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.20"^^xsd:string) "DNA glycosidase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.20"^^xsd:string) "3-methyladenine DNA glycosylase I"^^xsd:string) AnnotationAssertion( "DNA-3-methyladenine glycosylase I activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alkanesulfonate monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.5"^^xsd:string) "alkanesulfonate, reduced-FMN:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.5"^^xsd:string) "FMNH2-dependent aliphatic sulfonate monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.5"^^xsd:string) "FMNH(2)-dependent aliphatic sulfonate monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.5"^^xsd:string) "SsuD"^^xsd:string) AnnotationAssertion( "alkanesulphonate monooxygenase activity"^^xsd:string) AnnotationAssertion( "FMNH(2)-dependent alkanesulfonate monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-280"^^xsd:string) "Catalysis of the reaction: an alkanesulfonate + O2 + FMNH2 = an aldehyde + sulfite + H2O + FMN."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.5"^^xsd:string) "sulfate starvation-induced protein 6 activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GDP-mannose mannosyl hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:GDPMANMANHYDRO-RXN"^^xsd:string) "Catalysis of the reaction: GDP-alpha-D-mannose + H2O = GDP + D-mannose + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.6.5"^^xsd:string) "stringent factor activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.5"^^xsd:string) "GPSII"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.5"^^xsd:string) "guanosine 5',3'-polyphosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.5"^^xsd:string) "ppGpp synthetase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.5"^^xsd:string) "guanosine 3',5'-polyphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.5"^^xsd:string) "(p)ppGpp synthetase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.5"^^xsd:string) "ATP:GTP 3'-diphosphotransferase activity"^^xsd:string) AnnotationAssertion( "GTP pyrophosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.5"^^xsd:string) "ATP-GTP 3'-diphosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.5"^^xsd:string) "(p)ppGpp synthetase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.5"^^xsd:string) "guanosine pentaphosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.5"^^xsd:string) "GPSI"^^xsd:string) AnnotationAssertion(rdfs:label "GTP diphosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.5"^^xsd:string) "Catalysis of the reaction: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.32"^^xsd:string) "L-(+)-tartaric acid dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.32"^^xsd:string) "L-tartrate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.32"^^xsd:string) "tartaric acid dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.32"^^xsd:string) "tartrate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.32"^^xsd:string) "(R,R)-tartrate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.32"^^xsd:string) Annotation( "RHEA:15416"^^xsd:string) "Catalysis of the reaction: L-tartrate = H(2)O + oxaloacetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.32"^^xsd:string) "(R,R)-tartrate hydro-lyase (oxaloacetate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "L(+)-tartrate dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:LTAA-RXN"^^xsd:string) Annotation( "PMID:9228760"^^xsd:string) "Catalysis of the reaction: L-allo-threonine = glycine + acetaldehyde."^^xsd:string) AnnotationAssertion( "LtaA"^^xsd:string) AnnotationAssertion( "L-allo-threonine acetaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-allo-threonine aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.1.4"^^xsd:string) "L-arabinose ketol-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.4"^^xsd:string) "L-arabinose aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.4"^^xsd:string) Annotation( "RHEA:14824"^^xsd:string) "Catalysis of the reaction: L-arabinose = L-ribulose."^^xsd:string) AnnotationAssertion(rdfs:label "L-arabinose isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.3.16"^^xsd:string) "L-aspartate:oxygen oxidoreductase"^^xsd:string) AnnotationAssertion(rdfs:label "L-aspartate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.16"^^xsd:string) "Catalysis of the reaction: L-aspartate + O2 = iminosuccinate + hydrogen peroxide."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-carnitine dehydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "carnitine dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.89"^^xsd:string) Annotation( "RHEA:14580"^^xsd:string) "Catalysis of the reaction: (R)-carnitine = crotono-betaine + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.89"^^xsd:string) "L-carnitine hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.89"^^xsd:string) "L-carnitine hydro-lyase [4-(trimethylammonio)but-2-enoate-forming]"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.1.25"^^xsd:string) "L-fucose ketol-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.25"^^xsd:string) "Catalysis of the reaction: L-fucose = L-fuculose."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.25"^^xsd:string) "L-fucose aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-fucose isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.51"^^xsd:string) Annotation( "RHEA:12379"^^xsd:string) "Catalysis of the reaction: L-fuculose + ATP = L-fuculose 1-phosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.51"^^xsd:string) "L-fuculose kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.51"^^xsd:string) "L-fuculokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.51"^^xsd:string) "ATP:L-fuculose 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-fuculokinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.17"^^xsd:string) "L-fuculose 1-phosphate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.17"^^xsd:string) "fuculose aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.17"^^xsd:string) Annotation( "RHEA:12936"^^xsd:string) "Catalysis of the reaction: L-fuculose 1-phosphate = (S)-lactaldehyde + glycerone phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.17"^^xsd:string) "L-fuculose-1-phosphate S-lactaldehyde-lyase (glycerone-phosphate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.17"^^xsd:string) "L-fuculose-1-phosphate lactaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-fuculose-phosphate aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.1.14"^^xsd:string) Annotation( "RHEA:23163"^^xsd:string) "Catalysis of the reaction: L-rhamnose = L-rhamnulose."^^xsd:string) AnnotationAssertion(rdfs:label "L-rhamnose isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.14"^^xsd:string) "L-rhamnose ketol-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.14"^^xsd:string) "rhamnose isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.14"^^xsd:string) "L-rhamnose aldose-ketose-isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.16"^^xsd:string) "ribulokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "ribulokinase activity"^^xsd:string) AnnotationAssertion( "L-ribulokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.16"^^xsd:string) "ATP:L(or D)-ribulose 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.16"^^xsd:string) "Catalysis of the reaction: ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.4"^^xsd:string) "AraD"^^xsd:string) AnnotationAssertion(rdfs:label "L-ribulose-phosphate 4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.4"^^xsd:string) "L-Ru5P"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.4"^^xsd:string) "L-ribulose-5-phosphate 4-epimerase"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.4"^^xsd:string) "ribulose phosphate 4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.4"^^xsd:string) "L-ru5P activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.4"^^xsd:string) "phosphoribulose isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.4"^^xsd:string) Annotation( "RHEA:22371"^^xsd:string) "Catalysis of the reaction: L-ribulose 5-phosphate = D-xylulose 5-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.4"^^xsd:string) "L-ribulose 5-phosphate 4-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.103"^^xsd:string) Annotation( "RHEA:25657"^^xsd:string) "Catalysis of the reaction: L-threonine + NAD(+) = aminoacetone + CO(2) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.103"^^xsd:string) "L-threonine:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion( "threonine 3-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.103"^^xsd:string) "threonine dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-threonine 3-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.103"^^xsd:string) "L-threonine dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.53"^^xsd:string) "ATP:L-xylulose 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.53"^^xsd:string) "Catalysis of the reaction: ATP + L-xylulose = ADP + L-xylulose 5-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "L-xylulokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.53"^^xsd:string) "L-xylulose kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.53"^^xsd:string) "L-xylulokinase (phosphorylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.28"^^xsd:string) "N-acetylmuramoyl-L-alanine amidase type II"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.28"^^xsd:string) "acetylmuramoyl-alanine amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.28"^^xsd:string) "N-acetylmuramylalanine amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.28"^^xsd:string) "acetylmuramyl-alanine amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.28"^^xsd:string) "N-acetylmuramoyl-L-alanine amidase type I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.28"^^xsd:string) "peptidoglycan amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.28"^^xsd:string) "acetylmuramyl-L-alanine amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.28"^^xsd:string) "murein hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.28"^^xsd:string) "N-acetylmuramyl-L-alanine amidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylmuramoyl-L-alanine amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.28"^^xsd:string) "N-acetylmuramic acid L-alanine amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.28"^^xsd:string) "Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.28"^^xsd:string) "N-acylmuramyl-L-alanine amidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) Annotation( "EC:1.6.1.2"^^xsd:string) "NADPH-NAD transhydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) Annotation( "EC:1.6.1.2"^^xsd:string) "NADPH:NAD+ transhydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) Annotation( "EC:1.6.1.2"^^xsd:string) "Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) Annotation( "EC:1.6.1.2"^^xsd:string) "NADPH-NAD oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) Annotation( "EC:1.6.1.2"^^xsd:string) "H+-thase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) Annotation( "EC:1.6.1.2"^^xsd:string) "nicotinamide adenine dinucleotide (phosphate) transhydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) Annotation( "EC:1.6.1.2"^^xsd:string) "NADH transhydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) Annotation( "EC:1.6.1.2"^^xsd:string) "pyridine nucleotide transferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) Annotation( "EC:1.6.1.2"^^xsd:string) "NAD transhydrogenase"^^xsd:string) AnnotationAssertion(rdfs:label "NAD(P)+ transhydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) Annotation( "EC:1.6.1.2"^^xsd:string) "NADH-NADP-transhydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.1"^^xsd:string) Annotation( "EC:1.6.1.2"^^xsd:string) "energy-linked transhydrogenase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) "neuraminic acid aldolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylneuraminate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) "N-acetylneuraminic acid lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) "neuraminate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) "N-acetylneuraminic acid aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) "acetylneuraminate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) Annotation( "RHEA:23299"^^xsd:string) "Catalysis of the reaction: N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) "sialate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) "N-acetylneuraminate pyruvate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) "NALase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) "N-acetylneuraminic aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) "NPL"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) "sialic aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) "NANA lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) "neuraminic aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) "N-acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) "N-acetylneuraminic lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) "sialic acid aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) "acetylneuraminate pyruvate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.3"^^xsd:string) "N-acetylneuraminate aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-ethylmaleimide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-5101"^^xsd:string) "Catalysis of the reaction: N-ethylmaleimide + 2 H+ = N-ethylsuccinimide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.6.1.2"^^xsd:string) "NAD(P) transhydrogenase (AB-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.2"^^xsd:string) "pyridine nucleotide transhydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.2"^^xsd:string) "transhydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "NAD(P)+ transhydrogenase (AB-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.2"^^xsd:string) Annotation( "http://pubs.acs.org/cgi-bin/abstract.cgi/jacsat/1991/113/i07/f-pdf/f_ja00007a002.pdf"^^xsd:string) "Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD+ and B-specific (i.e. the pro-S hydrogen is transferred) with respect to NADP+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.1.2"^^xsd:string) "NADPH:NAD+ oxidoreductase (AB-specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NAD(P)H-dependent FMN reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "riboflavine mononucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NAD(P)H-FMN reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NAD(P)H:FMN oxidoreductase activity"^^xsd:string) AnnotationAssertion( "NAD(P)H dehydrogenase (FMN) activity"^^xsd:string) AnnotationAssertion(rdfs:label "FMN reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "riboflavin mononucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "SsuE"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "flavin mononucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "Catalysis of the reaction: FMNH2 + NAD(P)+ = FMN + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "FMNH2:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NAD(P)H(2):FMN oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide (phosphate)) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NAD(P)H:flavin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "flavine mononucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NAD(P)H2:FMN oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NAD(P)H2 dehydrogenase (FMN)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NAD(P)H(2) dehydrogenase (FMN) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.6.5.10"^^xsd:string) "NADPH:(quinone-acceptor) oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.10"^^xsd:string) "NADPH oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.10"^^xsd:string) "Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.10"^^xsd:string) "reduced nicotinamide adenine dinucleotide phosphate (quinone) dehydrogenase"^^xsd:string) AnnotationAssertion(rdfs:label "NADPH dehydrogenase (quinone) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "O antigen ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-5294"^^xsd:string) "Catalysis of the reaction: Lipid A-core + colanic acid = MLPS."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "O-antigen polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:12045108"^^xsd:string) "Catalysis of the polymerization of o-antigen chains. O-antigens are tetra- and pentasaccharide repeat units of the cell walls of Gram-negative bacteria and are a component of lipopolysaccharide."^^xsd:string) AnnotationAssertion(rdfs:label "O antigen polymerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "o-succinylbenzoate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.26"^^xsd:string) "2-succinylbenzoate:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.26"^^xsd:string) "Catalysis of the reaction: 2-succinylbenzoate + ATP + CoA = 2-succinylbenzoyl-CoA + AMP + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.26"^^xsd:string) "o-succinylbenzoyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.26"^^xsd:string) "OSB-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.26"^^xsd:string) "o-succinylbenzoate:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.26"^^xsd:string) "o-succinylbenzoyl-coenzyme A synthetase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "SAM-dependent methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "S-adenosylmethionine-dependent methyltransferase activity"^^xsd:string) AnnotationAssertion( "S-adenosyl methionine-dependent methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-2,3-diacylglucosamine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:LIPIDXSYNTHESIS-RXN"^^xsd:string) Annotation( "PMID:12000770"^^xsd:string) "Catalysis of the reaction: H2O + UDP-2,3-bis(3-hydroxymyristoyl)glucosamine = 2,3-bis(3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10026271"^^xsd:string) "Catalysis of the removal of an acetyl group from the 2-N position of glucosamine in the lipid A precursor UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.7"^^xsd:string) "pyruvate-uridine diphospho-N-acetyl-glucosamine transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.7"^^xsd:string) "phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.7"^^xsd:string) "phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.7"^^xsd:string) "phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.7"^^xsd:string) "phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.7"^^xsd:string) "pyruvate-UDP-acetylglucosamine transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.7"^^xsd:string) "phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.7"^^xsd:string) "pyruvate-uridine diphospho-N-acetylglucosamine transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.7"^^xsd:string) Annotation( "RHEA:18684"^^xsd:string) "Catalysis of the reaction: phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.7"^^xsd:string) "MurA transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.7"^^xsd:string) "pyruvic-uridine diphospho-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.7"^^xsd:string) "UDP-N-acetylglucosamine enoylpyruvyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.7"^^xsd:string) "enoylpyruvate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.7"^^xsd:string) "UDP-N-acetylglucosamine 1-carboxyvinyl-transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.7"^^xsd:string) "phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.14"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.14"^^xsd:string) "uridine diphospho-N-acetylglucosamine 2'-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.14"^^xsd:string) "UDP-N-acetyl-D-glucosamine 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.14"^^xsd:string) "uridine diphosphoacetylglucosamine 2'-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.14"^^xsd:string) "UDP-N-acetylglucosamine 2'-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.14"^^xsd:string) "uridine diphosphate-N-acetylglucosamine-2'-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.14"^^xsd:string) "UDP-GlcNAc-2-epimerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-N-acetylglucosamine 2-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.158"^^xsd:string) "uridine-5'-diphospho-N-acetyl-2-amino-2-deoxy-3-O-lactylglucose:NADP-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.158"^^xsd:string) "UDP-N-acetylenolpyruvoylglucosamine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.158"^^xsd:string) "MurB reductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.158"^^xsd:string) "uridine diphosphoacetylpyruvoylglucosamine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.158"^^xsd:string) "UDP-GlcNAc-enoylpyruvate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.158"^^xsd:string) "uridine diphospho-N-acetylglucosamine-enolpyruvate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.158"^^xsd:string) "UDP-N-acetylmuramate:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.158"^^xsd:string) "Catalysis of the reaction: UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "UDP-N-acetylmuramate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.158"^^xsd:string) "UDP-N-acetylglucosamine-enoylpyruvate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.8"^^xsd:string) "uridine diphosphate N-acetylmuramate:L-alanine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.8"^^xsd:string) "alanine-adding enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-N-acetylmuramate-L-alanine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.8"^^xsd:string) "UDP-N-acetylmuramyl:L-alanine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.8"^^xsd:string) Annotation( "RHEA:23375"^^xsd:string) "Catalysis of the reaction: L-alanine + ATP + UDP-N-acetylmuramate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.8"^^xsd:string) "UDP-N-acetylmuramate:L-alanine ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.8"^^xsd:string) "UDP-N-acetylmuramoyl-L-alanine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.8"^^xsd:string) "uridine-diphosphate-N-acetylmuramate:L-alanine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.8"^^xsd:string) "MurC synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.8"^^xsd:string) "L-Ala ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.8"^^xsd:string) "UDP-MurNAc:L-alanine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.8"^^xsd:string) "UDP-N-acetylmuramoylalanine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.8"^^xsd:string) "L-alanine-adding enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.8"^^xsd:string) "UDPMurNAc-L-alanine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.8"^^xsd:string) "UDP-acetylmuramyl-L-alanine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.8"^^xsd:string) "uridine 5'-diphosphate-N-acetylmuramyl-L-alanine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.8"^^xsd:string) "uridine diphospho-N-acetylmuramoylalanine synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.9"^^xsd:string) Annotation( "RHEA:16432"^^xsd:string) "Catalysis of the reaction: D-glutamate + ATP + UDP-N-acetylmuramoyl-L-alanine = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.9"^^xsd:string) "D-glutamate ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.9"^^xsd:string) "UDP-Mur-NAC-L-Ala:D-Glu ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.9"^^xsd:string) "UDP-N-acetylmuramoyl-L-alanine:glutamate ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.9"^^xsd:string) "uridine diphospho-N-acetylmuramoylalanyl-D-glutamate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.9"^^xsd:string) "UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.9"^^xsd:string) "MurD synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-N-acetylmuramoylalanine-D-glutamate ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.9"^^xsd:string) "D-glutamate-adding enzyme activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.13"^^xsd:string) "UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.13"^^xsd:string) Annotation( "RHEA:23679"^^xsd:string) "Catalysis of the reaction: meso-2,6-diaminopimelate + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.13"^^xsd:string) "UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:(L)-meso-2,6-diaminoheptanedioate gamma-ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.13"^^xsd:string) "UDP-N-acetylmuramyl-tripeptide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.13"^^xsd:string) "UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diamino-heptanedioate ligase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.13"^^xsd:string) "MurE synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.15"^^xsd:string) "Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.99.9"^^xsd:string) "UDP-D-galactopyranose furanomutase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-galactopyranose mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.9"^^xsd:string) "Catalysis of the reaction: UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.9"^^xsd:string) "UDPgalactopyranose mutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.45"^^xsd:string) "nucleosidediphosphate-sugar pyrophosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-sugar diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.45"^^xsd:string) "UDP-sugar hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.45"^^xsd:string) "UDP-sugar sugarphosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.45"^^xsd:string) "nucleosidediphosphate-sugar diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.45"^^xsd:string) "Catalysis of the reaction: UDP-sugar + H2O = UMP + sugar 1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.45"^^xsd:string) "UDP-sugar pyrophosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.14"^^xsd:string) "ACP hydrolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.14"^^xsd:string) "AcpH"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.14"^^xsd:string) "acyl-carrier-protein phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.14"^^xsd:string) "[acyl-carrier-protein] 4'-pantetheine-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.14"^^xsd:string) "Catalysis of the reaction: [acyl-carrier protein] + H2O = 4'-phosphopantetheine + apoprotein."^^xsd:string) AnnotationAssertion( "ACP phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.14"^^xsd:string) "holo-acyl-carrier-protein 4'-pantetheine-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[acyl-carrier-protein] phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.14"^^xsd:string) "acyl-carrier-protein 4'-pantetheine-phosphohydrolase activity"^^xsd:string) AnnotationAssertion( "[acyl-carrier protein] phosphodiesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.22"^^xsd:string) "acetate: SH-acyl-carrier-protein enzyme ligase (AMP)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.22"^^xsd:string) "acetate:citrate-(pro-3S)-lyase(thiol-form) ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.22"^^xsd:string) "citrate (pro-3S)-lyase ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.22"^^xsd:string) "citrate lyase synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.22"^^xsd:string) "acetate:HS-citrate lyase ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.22"^^xsd:string) "Catalysis of the reaction: ATP + acetate + (citrate (pro-3S)-lyase) (thiol form) = AMP + diphosphate + (citrate (pro-3S)-lyase) (acetyl form)."^^xsd:string) AnnotationAssertion(rdfs:label "[citrate (pro-3S)-lyase] ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.22"^^xsd:string) "citrate lyase ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.5"^^xsd:string) "isocitrate dehydrogenase (NADP+) kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.5"^^xsd:string) "STK3"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.5"^^xsd:string) "isocitrate dehydrogenase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.5"^^xsd:string) "IDH-K/P"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.5"^^xsd:string) "ATP:isocitrate dehydrogenase (NADP+) phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.5"^^xsd:string) "isocitrate dehydrogenase (NADP) kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[isocitrate dehydrogenase (NADP+)] kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.5"^^xsd:string) "IDHK/P"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.5"^^xsd:string) "ICDH kinase/phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.5"^^xsd:string) "IDH kinase/phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.5"^^xsd:string) "Catalysis of the reaction: ATP + (isocitrate dehydrogenase (NADP)) = ADP + (isocitrate dehydrogenase (NADP)) phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.5"^^xsd:string) "IDH kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.5"^^xsd:string) "isocitrate dehydrogenase kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.5"^^xsd:string) "isocitrate dehydrogenase kinase/phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.59"^^xsd:string) "uridylyl removing enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "[protein-PII] uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.59"^^xsd:string) "Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.59"^^xsd:string) "PII uridylyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.59"^^xsd:string) "uridyl removing enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.59"^^xsd:string) "UTP:protein-PII uridylyltransferase activity"^^xsd:string) AnnotationAssertion( "UTP:[protein-PII] uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.59"^^xsd:string) "protein-PII uridylyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.10"^^xsd:string) "DmpF"^^xsd:string) AnnotationAssertion(rdfs:label "acetaldehyde dehydrogenase (acetylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.10"^^xsd:string) "Catalysis of the reaction: acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.10"^^xsd:string) "acetaldehyde:NAD+ oxidoreductase (CoA-acetylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.10"^^xsd:string) "acylating acetaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.10"^^xsd:string) "aldehyde dehydrogenase (acylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.10"^^xsd:string) "ADA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.3.8"^^xsd:string) "acyl-CoA:acetate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.8"^^xsd:string) "Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.8"^^xsd:string) "butyryl coenzyme A transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.8"^^xsd:string) "succinyl-CoA:acetate CoA transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.8"^^xsd:string) "acetate coenzyme A-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.8"^^xsd:string) "acetyl-CoA:acetoacetate CoA transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.8"^^xsd:string) "butyryl CoA:acetate CoA transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.2.1"^^xsd:string) "acetate kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.1"^^xsd:string) "AK activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.1"^^xsd:string) "Catalysis of the reaction: ATP + acetate = ADP + acetyl phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "acetate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.1"^^xsd:string) "AckA"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.1"^^xsd:string) "acetokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.1"^^xsd:string) "ATP:acetate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.1"^^xsd:string) "acetic kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.16"^^xsd:string) "acetylornithinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.16"^^xsd:string) "Catalysis of the reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.16"^^xsd:string) "N-acetylornithinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.16"^^xsd:string) "N2-acetyl-L-ornithine amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetylornithine deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.16"^^xsd:string) "2-N-acetyl-L-ornithine amidohydrolase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.40"^^xsd:string) "acyl-acyl-carrier-protein-phospholipid O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.40"^^xsd:string) "Catalysis of the reaction: acyl-[acyl-carrier protein] + O-(2-acyl-sn-glycero-3-phospho)ethanolamine = [acyl-carrier protein] + O-(1-beta-acyl-2-acyl-sn-glycero-3-phospho)ethanolamine."^^xsd:string) AnnotationAssertion( "acyl-[acyl-carrier protein]-phospholipid O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.40"^^xsd:string) "acyl-acyl-carrier-protein:O-(2-acyl-sn-glycero-3-phospho)-ethanolamine O-acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity"^^xsd:string) AnnotationAssertion( "acyl-ACP-phospholipid O-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.129"^^xsd:string) "uridine diphosphoacetylglucosamine acyltransferase activity"^^xsd:string) AnnotationAssertion( "acyl-[acyl-carrier protein]-UDP-N-acetylglucosamine O-acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.129"^^xsd:string) "(R)-3-hydroxytetradecanoyl-acyl-carrier-protein:UDP-N-acetylglucosamine 3-O-(3-hydroxytetradecanoyl)transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.129"^^xsd:string) "UDP-N-acetylglucosamine acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.129"^^xsd:string) "Catalysis of the reaction: (R)-3-hydroxytetradecanoyl-[acyl-carrier protein] + UDP-N-acetylglucosamine = [acyl-carrier protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.129"^^xsd:string) "acyl-acyl-carrier-protein-UDP-N-acetylglucosamine O-acyltransferase"^^xsd:string) AnnotationAssertion( "acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "CMP-NeuNAc synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "CMP-sialate diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "CMP-sialic synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acylneuraminate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "CMP-sialic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "CMP-NANA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "cytidine monophosphoacetylneuraminic synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "CMP-N-acetylneuraminate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "acetylneuraminate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "CMP-sialate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "cytidine 5'-monophosphosialic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "CMP-N-acetylneuraminate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "acylneuraminate cytidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "CMP-N-acetylneuraminic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "CMP-N-acetylneuraminic acid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "CMP-NeuAc synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "CMP-sialate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "cytidine 5'-monophospho-N-acetylneuraminic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "Catalysis of the reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "cytidine 5-monophosphate N-acetylneuraminic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "cytidine monophosphosialic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "cytidine monophosphosialate synthetase activity"^^xsd:string) AnnotationAssertion( "CTP:N-acylneuraminate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "CMP-sialate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "CMP-Neu5Ac synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.43"^^xsd:string) "cytidine monophosphosialate pyrophosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.9"^^xsd:string) "S-adenosylhomocysteine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.9"^^xsd:string) "5'-methyladenosine nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.9"^^xsd:string) "S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.9"^^xsd:string) "AdoHcy/MTA nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.9"^^xsd:string) "S-adenosylhomocysteine nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.9"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenine + S-D-ribosyl-L-homocysteine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.9"^^xsd:string) "S-adenosyl-L-homocysteine homocysteinylribohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "adenosylhomocysteine nucleosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.11"^^xsd:string) "SpeB"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.11"^^xsd:string) Annotation( "RHEA:13932"^^xsd:string) "Catalysis of the reaction: agmatine + H(2)O = putrescine + urea."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.11"^^xsd:string) "agmatine amidinohydrolase"^^xsd:string) AnnotationAssertion(rdfs:label "agmatinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.11"^^xsd:string) "agmatine ureohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alanine racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.1"^^xsd:string) "L-alanine racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.1"^^xsd:string) Annotation( "RHEA:20252"^^xsd:string) "Catalysis of the reaction: L-alanine = D-alanine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0684"^^xsd:string) "Catalysis of the reaction: octane hydroperoxide + NADH + H+ = H2O + NAD+ + 1-octanol."^^xsd:string) AnnotationAssertion(rdfs:label "alkyl hydroperoxide reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "allose 6-phosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-303"^^xsd:string) "Catalysis of the reaction: D-allose-6-phosphate = D-allulose-6-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.55"^^xsd:string) "D-allose-6-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.55"^^xsd:string) "allokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.55"^^xsd:string) "D-allokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.55"^^xsd:string) "Catalysis of the reaction: ATP + D-allose = ADP + D-allose 6-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "allose kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.55"^^xsd:string) "ATP:D-allose 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.55"^^xsd:string) "allokinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.93"^^xsd:string) "Catalysis of the reaction: alpha,alpha-trehalose 6-phosphate + H2O = D-glucose + D-glucose 6-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.93"^^xsd:string) "phosphotrehalase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.93"^^xsd:string) "trehalose-6-phosphate hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha,alpha-phosphotrehalase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.93"^^xsd:string) "alpha,alpha-trehalose-6-phosphate phosphoglucohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.7"^^xsd:string) "D-altronate hydro-lyase (2-dehydro-3-deoxy-D-galactonate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.7"^^xsd:string) "D-altronate hydro-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "altronate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.7"^^xsd:string) Annotation( "RHEA:15960"^^xsd:string) "Catalysis of the reaction: D-altronate = 2-dehydro-3-deoxy-D-gluconate + H(2)O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.1.3"^^xsd:string) "Catalysis of the reaction: D-arabinose = D-ribulose."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.3"^^xsd:string) "D-arabinose ketol-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.3"^^xsd:string) "D-arabinose aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arabinose isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.3"^^xsd:string) "D-arabinose isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.3"^^xsd:string) "D-arabinose(L-fucose) isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.109"^^xsd:string) "AST activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.109"^^xsd:string) "arginine and ornithine N(2)-succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.109"^^xsd:string) "succinyl-CoA:L-arginine 2-N-succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.109"^^xsd:string) "arginine and ornithine N2-succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.109"^^xsd:string) "succinyl-CoA:L-arginine N2-succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.109"^^xsd:string) "AOST activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.109"^^xsd:string) "AstA"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.109"^^xsd:string) "Catalysis of the reaction: succinyl-CoA + L-arginine = CoA + N2-succinyl-L-arginine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.109"^^xsd:string) "arginine succinyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arginine N-succinyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.19"^^xsd:string) Annotation( "RHEA:17644"^^xsd:string) "Catalysis of the reaction: L-arginine + H(+) = agmatine + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.19"^^xsd:string) "SpeA"^^xsd:string) AnnotationAssertion(rdfs:label "arginine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.19"^^xsd:string) "L-arginine carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.19"^^xsd:string) "L-arginine carboxy-lyase (agmatine-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "aromatic amino acid transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.57"^^xsd:string) "aromatic amino acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.57"^^xsd:string) "ArAT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.57"^^xsd:string) "aromatic-amino-acid transaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aromatic-amino-acid:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion( "aromatic aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.57"^^xsd:string) "Catalysis of the reaction: an aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arsenate reductase (glutaredoxin) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.20.4.1"^^xsd:string) Annotation( "GOC:kd"^^xsd:string) Annotation( "PMID:10593884"^^xsd:string) "Catalysis of the reaction: arsenate + reduced glutaredoxin = arsenite + oxidized glutaredoxin. Glutaredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is ( NADPH -> glutathione reductase (EC:1.6.4.2) -> ) glutathione -> glutaredoxin -> arsenate reductase, i.e. glutathione is reduced by glutathione reductase and glutaredoxin is reduced by glutathione."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.20.4.1"^^xsd:string) "glutharedoxin:arsenate oxidoreductase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "NAD synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.5"^^xsd:string) "NAD(+) synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.5"^^xsd:string) "Catalysis of the reaction: ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.5"^^xsd:string) "diphosphopyridine nucleotide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.5"^^xsd:string) "NAD synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.5"^^xsd:string) "deamido-NAD+:ammonia ligase (AMP-forming)"^^xsd:string) AnnotationAssertion( "NAD synthase (AMP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "NAD+ synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.5"^^xsd:string) "nicotinamide adenine dinucleotide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.5"^^xsd:string) "NAD+ synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of P(1),P(4)-bis(5'-nucleosyl)tetraphosphate into two nucleotides."^^xsd:string) AnnotationAssertion(rdfs:label "bis(5'-nucleosyl)-tetraphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.1.1"^^xsd:string) "L-aspartate ammonia-lyase (fumarate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.1"^^xsd:string) "Catalysis of the reaction: L-aspartate = fumarate + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.1"^^xsd:string) "L-aspartase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aspartate ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.1"^^xsd:string) "aspartase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.1"^^xsd:string) "L-aspartate ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.1"^^xsd:string) "fumaric aminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.4.19.5"^^xsd:string) "beta-aspartyl dipeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.19.5"^^xsd:string) "beta-aspartyl peptidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-aspartyl-peptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.19.5"^^xsd:string) "Catalysis of the cleavage of a beta-linked aspartic residue from the N-terminus of a polypeptide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.2.6"^^xsd:string) "penicillin amido-beta-lactamhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.6"^^xsd:string) "exopenicillinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.6"^^xsd:string) "ampicillinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.6"^^xsd:string) "penicillinase I, II"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.6"^^xsd:string) "Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid."^^xsd:string) AnnotationAssertion(rdfs:label "beta-lactamase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.6"^^xsd:string) "beta-lactamase I-III"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.6"^^xsd:string) "beta-lactamase AME I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.6"^^xsd:string) "beta-lactam hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.6"^^xsd:string) "penicillin beta-lactamase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.6"^^xsd:string) "beta-lactamase A, B, C"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.6"^^xsd:string) "cephalosporin-beta-lactamase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.6"^^xsd:string) "neutrapen"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.2.6"^^xsd:string) Annotation( "RHEA:20116"^^xsd:string) "Catalysis of the reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "beta-phosphoglucomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.6"^^xsd:string) "beta-D-glucose 1,6-phosphomutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.8"^^xsd:string) "BADH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.8"^^xsd:string) "betaine aldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.8"^^xsd:string) "betaine aldehyde oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.8"^^xsd:string) "betaine-aldehyde:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "betaine-aldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.8"^^xsd:string) "BetB"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.8"^^xsd:string) "Catalysis of the reaction: betaine aldehyde + NAD+ + H2O = betaine + NADH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.41"^^xsd:string) "diadenosine polyphosphate hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.41"^^xsd:string) "diadenosinetetraphosphatase (symmetrical) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.41"^^xsd:string) "adenosine tetraphosphate phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.41"^^xsd:string) "diadenosine tetraphosphate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.41"^^xsd:string) "diadenosine 5',5'''-P(1),P(4)-tetraphosphate pyrophosphohydrolase activity"^^xsd:string) AnnotationAssertion( "diadenosine tetraphosphatase (symmetrical)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.41"^^xsd:string) "P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleosidebisphosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.41"^^xsd:string) "1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleosidebisphosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.41"^^xsd:string) Annotation( "RHEA:24255"^^xsd:string) "Catalysis of the reaction: P(1),P(4)-bis(5'-adenosyl) tetraphosphate + H(2)O = 2 ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.41"^^xsd:string) "diadenosine 5',5'''-P1,P4-tetraphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.41"^^xsd:string) "Ap(4)A hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.41"^^xsd:string) "dinucleosidetetraphosphate (symmetrical)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.41"^^xsd:string) "symmetrical diadenosine tetraphosphate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.41"^^xsd:string) "Ap4A hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.41"^^xsd:string) "diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.41"^^xsd:string) "dinucleosidetetraphosphatase (symmetrical) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.41"^^xsd:string) "bis(5'-adenosyl) tetraphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.2.2"^^xsd:string) "Catalysis of the reaction: ATP + NH3 + CO2 = ADP + carbamoyl phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.2"^^xsd:string) "carbamoyl phosphokinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "carbamate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.2"^^xsd:string) "ATP:carbamate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.2"^^xsd:string) "carbamyl phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.2"^^xsd:string) "CKase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.2.4"^^xsd:string) "carbon monoxide oxygenase (cytochrome b-561) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.2.4"^^xsd:string) "carbon-monoxide dehydrogenase (cytochrome b-561)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.2.4"^^xsd:string) "carbon monoxide:methylene blue oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.2.4"^^xsd:string) "carbon monoxide oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.2.4"^^xsd:string) "Catalysis of the reaction: CO + H2O + ferrocytochrome b-561 = CO2 + 2 H+ + 2 ferricytochrome b-561."^^xsd:string) AnnotationAssertion( "carbon monoxide oxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "carbon-monoxide oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.2.4"^^xsd:string) "carbon monoxide,water:cytochrome b-561 oxidoreductase activity"^^xsd:string) AnnotationAssertion( "cytochrome b561"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.45"^^xsd:string) "maleylacetate enol-lactonase activity"^^xsd:string) AnnotationAssertion(rdfs:label "carboxymethylenebutenolidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.45"^^xsd:string) "carboxymethylene butenolide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.45"^^xsd:string) "4-carboxymethylenebut-2-en-4-olide lactonohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.45"^^xsd:string) "dienelactone hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.45"^^xsd:string) "Catalysis of the reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4 oxohex-2-enedioate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.23"^^xsd:string) "CPEP phosphonomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.23"^^xsd:string) "carboxyphosphonoenolpyruvate phosphonomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.23"^^xsd:string) "1-carboxyvinyl carboxyphosphonate phosphorylmutase (decarboxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "carboxyvinyl-carboxyphosphonate phosphorylmutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.23"^^xsd:string) "Catalysis of the reaction: 1-carboxyvinyl carboxyphosphonate = 3-(hydrohydroxyphosphoryl)pyruvate + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cardiolipin synthase 2 activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol."^^xsd:string) AnnotationAssertion(rdfs:label "cardiolipin synthase activity"^^xsd:string) AnnotationAssertion( "cardiolipin synthetase 2 activity"^^xsd:string) AnnotationAssertion( "diphosphatidylglycerol synthase activity"^^xsd:string) AnnotationAssertion( "cardiolipin synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:CARNRACE-RXN"^^xsd:string) "Catalysis of the reaction: D-carnitine = L-carnitine."^^xsd:string) AnnotationAssertion(rdfs:label "carnitine racemase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.4"^^xsd:string) "alkali cellulase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.4"^^xsd:string) "1,4-(1,3;1,4)-beta-D-glucan 4-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cellulase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.4"^^xsd:string) "cellulosin AP"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.4"^^xsd:string) "endo-1,4-beta-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.4"^^xsd:string) "avicelase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.4"^^xsd:string) "endoglucanase D"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.4"^^xsd:string) "pancellase SS"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.4"^^xsd:string) "Catalysis of the endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.4"^^xsd:string) "beta-1,4-endoglucan hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.4"^^xsd:string) "carboxymethyl cellulase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.4"^^xsd:string) "beta-1,4-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.4"^^xsd:string) "cellulase A 3"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.4"^^xsd:string) "endoglucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.4"^^xsd:string) "celluase A"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.4"^^xsd:string) "9.5 cellulase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.4"^^xsd:string) "celludextrinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.4"^^xsd:string) "endo-1,4-beta-D-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.4"^^xsd:string) "endo-1,4-beta-D-glucanohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.28"^^xsd:string) "acetyl-CoA:chloramphenicol 3-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.28"^^xsd:string) "chloramphenicol acetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.28"^^xsd:string) "CAT II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.28"^^xsd:string) "CAT I"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.28"^^xsd:string) Annotation( "RHEA:18424"^^xsd:string) "Catalysis of the reaction: chloramphenicol + acetyl-CoA = chloramphenicol 3-acetate + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.28"^^xsd:string) "chloramphenicol acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.28"^^xsd:string) "chloramphenicol transacetylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "chloramphenicol O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.28"^^xsd:string) "CAT III"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "choline dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.1"^^xsd:string) "choline:(acceptor) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.1"^^xsd:string) "choline:(acceptor) 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.1"^^xsd:string) "choline-cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.1"^^xsd:string) "choline:acceptor 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.1"^^xsd:string) "choline oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.1"^^xsd:string) Annotation( "RHEA:17436"^^xsd:string) "Catalysis of the reaction: A + choline = AH(2) + betaine aldehyde."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3.40"^^xsd:string) "UbiC"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.40"^^xsd:string) "CPL"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.40"^^xsd:string) "chorismate pyruvate-lyase (4-hydroxybenzoate-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.40"^^xsd:string) "CL"^^xsd:string) AnnotationAssertion(rdfs:label "chorismate lyase activity"^^xsd:string) AnnotationAssertion( "4-hydroxybenzoate synthetase activity"^^xsd:string) AnnotationAssertion( "chorismate pyruvate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.40"^^xsd:string) Annotation( "RHEA:16508"^^xsd:string) "Catalysis of the reaction: chorismate = 4-hydroxybenzoate + pyruvate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.3.10"^^xsd:string) "acetyl-CoA:citrate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.10"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + citrate = acetate + (3S)-citryl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "citrate CoA-transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3.6"^^xsd:string) "citritase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.6"^^xsd:string) "citrate oxaloacetate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.6"^^xsd:string) "citridesmolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.6"^^xsd:string) Annotation( "RHEA:10763"^^xsd:string) "Catalysis of the reaction: citrate = acetate + oxaloacetate."^^xsd:string) AnnotationAssertion(rdfs:label "citrate (pro-3S)-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.6"^^xsd:string) "citratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.6"^^xsd:string) "citrate oxaloacetate-lyase [(pro-3S)-CH2COO-->acetate]"^^xsd:string) AnnotationAssertion( "citrate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.6"^^xsd:string) "citric aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.6"^^xsd:string) "citrate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.6"^^xsd:string) "citrase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3.34"^^xsd:string) "Catalysis of the reaction: (3S)-citryl-CoA = acetyl-CoA + oxaloacetate."^^xsd:string) AnnotationAssertion(rdfs:label "citryl-CoA lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.34"^^xsd:string) "(3S)-citryl-CoA oxaloacetate-lyase (acetyl-CoA-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.34"^^xsd:string) "(3S)-citryl-CoA oxaloacetate-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.17"^^xsd:string) "aquocob(I)alamin vitamin B12s adenosyltransferase activity"^^xsd:string) AnnotationAssertion( "cob(I)alamin adenosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.17"^^xsd:string) "vitamin B12s adenosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.17"^^xsd:string) "Catalysis of the reaction: ATP + cob(I)alamin + H2O = phosphate + diphosphate + adenosylcobalamin."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.17"^^xsd:string) "aquacob(I)alamin adenosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.17"^^xsd:string) "ATP:cob(I)yrinic acid-a,c-diamide cobeta-adenosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.17"^^xsd:string) "ATP:cob(I)alamin Co-beta-adenosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.17"^^xsd:string) "CobA"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.17"^^xsd:string) "ATP:corrinoid adenosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.17"^^xsd:string) "ATP:cob(I)alamin cobeta-adenosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cob(I)yrinic acid a,c-diamide adenosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cobalamin 5'-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:COBALAMIN5PSYN-RXN"^^xsd:string) "Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole-5'-phosphate = adenosylcobalamin-5'-phosphate + GMP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cobinamide kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:1655696"^^xsd:string) Annotation( "http://www.mblab.gla.ac.uk/"^^xsd:string) "Catalysis of the reaction: cobinamide + ATP = cobinamide phosphate + ADP. This reaction is the phosphorylation of the hydroxyl group of the 1-amino-2-propanol residue of cobinamide, in the presence of ATP, to form cobinamide phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.62"^^xsd:string) Annotation( "RHEA:22715"^^xsd:string) "Catalysis of the reaction: adenosylcobinamide phosphate + GTP + 2 H(+) = adenosylcobinamide-GDP + diphosphate."^^xsd:string) AnnotationAssertion( "AdoCbi kinase/AdoCbi-phosphate guanylyltransferase"^^xsd:string) AnnotationAssertion( "GTP:cobinamide phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion( "adenosylcobinamide-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion( "adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase"^^xsd:string) AnnotationAssertion( "GTP:adenosylcobinamide-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cobinamide phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion( "CobU"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.22.-"^^xsd:string) "Holliday junction endonuclease CCE1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.-"^^xsd:string) "endonuclease X3 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.-"^^xsd:string) "Holliday junction-resolving endoribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.-"^^xsd:string) "endonuclease RuvC activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.-"^^xsd:string) "RusA Holliday junction resolvase activity"^^xsd:string) AnnotationAssertion(rdfs:label "crossover junction endodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion( "endodeoxyribonuclease RUS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.-"^^xsd:string) "Hje endonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.-"^^xsd:string) "Holliday junction nuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.4"^^xsd:string) "Catalysis of the endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.-"^^xsd:string) "cruciform-cutting endonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.-"^^xsd:string) "resolving enzyme CCE1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.-"^^xsd:string) "Endo X3 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.4"^^xsd:string) "RusA holliday junction resolvase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.-"^^xsd:string) "SpCCe1 Holliday junction resolvase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.-"^^xsd:string) "Holliday junction resolvase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.-"^^xsd:string) "endonuclease VII activity"^^xsd:string) AnnotationAssertion( "crossover junction endoribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.-"^^xsd:string) "RuvC endonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.-"^^xsd:string) "RusA endonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.4"^^xsd:string) "SpCCe1 holliday junction resolvase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.-"^^xsd:string) "Holliday junction-cleaving endonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.4"^^xsd:string) "endo X3"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cupric reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10510271"^^xsd:string) "Catalysis of the reaction: Cu+ + NAD+ + H+ = Cu2+ + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cyanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.104"^^xsd:string) "Catalysis of the reaction: cyanate + H2O = carbamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.104"^^xsd:string) "cyanate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.104"^^xsd:string) "cyanate C-N-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyanate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.104"^^xsd:string) "cyanate aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.104"^^xsd:string) "carbamate hydro-lyase activity"^^xsd:string) AnnotationAssertion( "cyanate lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclopropane-fatty-acyl-phospholipid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.79"^^xsd:string) "CFA synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.79"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.79"^^xsd:string) "cyclopropane synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.79"^^xsd:string) "unsaturated-phospholipid methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.79"^^xsd:string) "S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.79"^^xsd:string) "cyclopropane synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.79"^^xsd:string) "cyclopropane fatty acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.79"^^xsd:string) "cyclopropane fatty acid synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cysteine sulfinate desulfinase activity"^^xsd:string) AnnotationAssertion( "cysteine sulphinate desulphinase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-279"^^xsd:string) "Catalysis of the reaction: 3-sulfinoalanine = L-alanine + sulfite."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "MetaCyc:CYT-UBIQUINOL-OXID-RXN"^^xsd:string) "Catalysis of the reaction: ubiquinol + O2 = ubiquinone + 2 H2O; cytochrome O is the electron acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "cytochrome o ubiquinol oxidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN0-384"^^xsd:string) "Catalysis of the reaction: deoxy-ATP + H2O = dAMP + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "dATP pyrophosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dCTP deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.13"^^xsd:string) "dCTP aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.13"^^xsd:string) "deoxycytidine triphosphate deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.13"^^xsd:string) "5-methyl-dCTP deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.13"^^xsd:string) "Catalysis of the reaction: dCTP + H2O = dUTP + NH3."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.13"^^xsd:string) "dTDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.13"^^xsd:string) "dTDP-L-rhamnose synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.13"^^xsd:string) "TDP-4-ketorhamnose 3,5-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.13"^^xsd:string) Annotation( "RHEA:16972"^^xsd:string) "Catalysis of the reaction: dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-L-mannose."^^xsd:string) AnnotationAssertion(rdfs:label "dTDP-4-dehydrorhamnose 3,5-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.13"^^xsd:string) "thymidine diphospho-4-ketorhamnose 3,5-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.13"^^xsd:string) "dTDP-4-keto-6-deoxyglucose 3,5-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.13"^^xsd:string) "TDP-4-keto-L-rhamnose-3,5-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.133"^^xsd:string) "dTDP-6-deoxy-L-mannose:NADP+ 4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.133"^^xsd:string) "thymidine diphospho-4-ketorhamnose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.133"^^xsd:string) "dTDP-6-deoxy-L-mannose dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dTDP-4-dehydrorhamnose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.133"^^xsd:string) "reductase, thymidine diphospho-4-ketorhamnose"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.133"^^xsd:string) "dTDP-4-ketorhamnose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.133"^^xsd:string) Annotation( "RHEA:21799"^^xsd:string) "Catalysis of the reaction: dTDP-6-deoxy-L-mannose + NADP(+) = dTDP-4-dehydro-6-deoxy-L-mannose + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.133"^^xsd:string) "TDP-4-keto-rhamnose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.133"^^xsd:string) "dTDP-4-keto-L-rhamnose reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "deoxyguanosinetriphosphate triphosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.5.1"^^xsd:string) "dGTP triphosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.5.1"^^xsd:string) "deoxyguanosine triphosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dGTPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.5.1"^^xsd:string) "deoxy-GTPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.5.1"^^xsd:string) Annotation( "RHEA:15196"^^xsd:string) "Catalysis of the reaction: dGTP + H(2)O = 2'-deoxyguanosine + 2 H(+) + triphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.5.1"^^xsd:string) "deoxyguanosine triphosphate triphosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.5.1"^^xsd:string) "deoxyguanosine 5-triphosphate triphosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.21.2"^^xsd:string) "Catalysis of the endonucleolytic cleavage to 5'-phosphooligonucleotide end-products."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.2"^^xsd:string) "endodeoxyribonuclease IV (phage T4-induced) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.2"^^xsd:string) "redoxyendonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.2"^^xsd:string) "endodeoxyribonuclease IV (phage T(4)-induced) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.2"^^xsd:string) "Escherichia coli endonuclease II"^^xsd:string) AnnotationAssertion(rdfs:label "deoxyribonuclease IV (phage-T4-induced) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.2"^^xsd:string) "DNA-adenine-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.2"^^xsd:string) "deoxyribonuclease IV (phage T4-induced) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.2"^^xsd:string) "endonuclease IV activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.2"^^xsd:string) "endonuclease II"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.2"^^xsd:string) "deoxriboendonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.2"^^xsd:string) "E. coli endonuclease IV"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "di-trans,poly-cis-decaprenylcistransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.31"^^xsd:string) "undecaprenyl pyrophosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.31"^^xsd:string) "UPP synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.31"^^xsd:string) "di-trans,poly-cis-undecaprenyl-diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.31"^^xsd:string) "undecaprenyl pyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion( "undecaprenyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.31"^^xsd:string) "undecaprenyl diphosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.31"^^xsd:string) "Catalysis of the reaction: di-trans-poly-cis-decaprenyl diphosphate + isopentenyl diphosphate = diphosphate + di-trans-poly-cis-undecaprenyl diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.31"^^xsd:string) "di-trans,poly-cis-decaprenyl-diphosphate:isopentenyl-diphosphate undecaprenylcistransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.31"^^xsd:string) "undecaprenyl-diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.31"^^xsd:string) "bactoprenyl-diphosphate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "diaminohydroxyphosphoribosylaminopyrimidine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.26"^^xsd:string) "2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 2-aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.26"^^xsd:string) "2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine 2-aminohydrolase activity"^^xsd:string) AnnotationAssertion( "2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.26"^^xsd:string) Annotation( "RHEA:21871"^^xsd:string) "Catalysis of the reaction: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(2)O + H(+) = 5-amino-6-(5-phosphoribosylamino)uracil + NH(4)(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.20"^^xsd:string) "meso-diaminopimelate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.20"^^xsd:string) Annotation( "RHEA:15104"^^xsd:string) "Catalysis of the reaction: meso-2,6-diaminopimelate + H(+) = L-lysine + CO(2)."^^xsd:string) AnnotationAssertion(rdfs:label "diaminopimelate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.20"^^xsd:string) "meso-2,6-diaminoheptanedioate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.20"^^xsd:string) "diaminopimelic acid decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.20"^^xsd:string) "DAP decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.20"^^xsd:string) "meso-2,6-diaminoheptanedioate carboxy-lyase (L-lysine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.20"^^xsd:string) "DAP-decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "diaminopimelate epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.7"^^xsd:string) Annotation( "RHEA:15396"^^xsd:string) "Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.7"^^xsd:string) "LL-2,6-diaminoheptanedioate 2-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.1.15"^^xsd:string) "Catalysis of the reaction: 2,3-diaminopropionate + H2O = pyruvate + 2 NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.15"^^xsd:string) "2,3-diaminopropionate ammonia-lyase (adding H2O; pyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.15"^^xsd:string) "diaminopropionatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.15"^^xsd:string) "2,3-diaminopropionate ammonia-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "diaminopropionate ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.15"^^xsd:string) "alpha,beta-diaminopropionate ammonia-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "dihydrodipicolinate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.26"^^xsd:string) "dihydrodipicolinic acid reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.8"^^xsd:string) "Catalysis of the reaction: (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.26"^^xsd:string) "2,3,4,5-tetrahydrodipicolinate:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxy-tetrahydrodipicolinate reductase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-hydroxy-tetrahydrodipicolinate synthase"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.52"^^xsd:string) "DHDPS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.52"^^xsd:string) "dihydrodipicolinate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.52"^^xsd:string) "L-aspartate-4-semialdehyde hydro-lyase (adding pyruvate and cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.3.7"^^xsd:string) Annotation( "RHEA:14848"^^xsd:string) "Catalysis of the reaction: pyruvate + L-aspartate-4-semialdehyde = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.52"^^xsd:string) "L-aspartate-4-semialdehyde hydro-lyase [adding pyruvate and cyclizing; (S)-2,3-dihydropyridine-2,6-dicarboxylate-forming]"^^xsd:string) AnnotationAssertion( "dihydrodipicolinate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.52"^^xsd:string) "dihydrodipicolinic acid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.52"^^xsd:string) "dihydropicolinate synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.12"^^xsd:string) "folylpoly-(gamma-glutamate) synthetase-dihydrofolate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.12"^^xsd:string) "7,8-dihydropteroate:L-glutamate ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.12"^^xsd:string) "dihydrofolate synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dihydrofolate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.12"^^xsd:string) "7,8-dihydropteroate:L-glutamate ligase (ADP) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.12"^^xsd:string) "7,8-dihydrofolate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.12"^^xsd:string) "H2-folate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.12"^^xsd:string) "FHFS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.12"^^xsd:string) "dihydrofolate synthetase-folylpolyglutamate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.12"^^xsd:string) "Catalysis of the reaction: ATP + dihydropterate + L-glutamate = ADP + phosphate + dihydrofolate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.12"^^xsd:string) "H(2)-folate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.12"^^xsd:string) "DHFS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.12"^^xsd:string) "dihydropteroate:L-glutamate ligase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.12"^^xsd:string) "FHFS/FPGS activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "diphosphate-purine nucleoside kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.143"^^xsd:string) "pyrophosphate-dependent nucleoside kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.143"^^xsd:string) "diphosphate:purine nucleoside phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.143"^^xsd:string) "pyrophosphate-purine nucleoside kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.143"^^xsd:string) "diphosphate-dependent nucleoside kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.143"^^xsd:string) "Catalysis of the reaction: diphosphate + a purine nucleoside = monophosphate + a purine mononucleotide."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.-"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:kah"^^xsd:string) Annotation( "GOC:pde"^^xsd:string) Annotation( "PMID:11468293"^^xsd:string) "Catalysis of the hydrolysis of nonterminal (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, endochitinases cleave randomly within the chitin chain."^^xsd:string) AnnotationAssertion(rdfs:label "endochitinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.27.6"^^xsd:string) "Catalysis of the endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates."^^xsd:string) AnnotationAssertion(rdfs:label "Enterobacter ribonuclease activity"^^xsd:string) AnnotationAssertion( "Enterobacter RNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.6"^^xsd:string) "enterobacter ribonuclease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "enterobactin esterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "enterochelin esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-1661"^^xsd:string) Annotation( "PMID:4565531"^^xsd:string) "Catalysis of the reaction: enterobactin + 3 H2O = 3 N-23-dihydroxybenzoyl-L-serine + 3 H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.1.7"^^xsd:string) "ethanolamine ammonia-lyase (acetaldehyde-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "ethanolamine ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.7"^^xsd:string) "Catalysis of the reaction: ethanolamine = acetaldehyde + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.7"^^xsd:string) "ethanolamine deaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.11.1"^^xsd:string) "Escherichia coli exonuclease I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.1"^^xsd:string) "E. coli exonuclease I"^^xsd:string) AnnotationAssertion(rdfs:label "exodeoxyribonuclease I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.1"^^xsd:string) "E. coli exonuclease I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.1"^^xsd:string) "Catalysis of the degradation of single-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.1"^^xsd:string) "exonuclease I activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.11.2"^^xsd:string) "Escherichia coli exonuclease III"^^xsd:string) AnnotationAssertion(rdfs:label "exodeoxyribonuclease III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.2"^^xsd:string) "exonuclease III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.2"^^xsd:string) "E. coli exonuclease III"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.2"^^xsd:string) "E. coli exonuclease III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.2"^^xsd:string) "endoribonuclease III"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.2"^^xsd:string) "Catalysis of the degradation of double-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.11.5"^^xsd:string) "Escherichia coli exonuclease V"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.5"^^xsd:string) "E. coli exonuclease V"^^xsd:string) AnnotationAssertion(rdfs:label "exodeoxyribonuclease V activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.5"^^xsd:string) "exonuclease V activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.5"^^xsd:string) "gene recBCD enzymes"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.5"^^xsd:string) "Catalysis of the exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.5"^^xsd:string) "gene recBC endoenzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.5"^^xsd:string) "RecBC deoxyribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.5"^^xsd:string) "gene recBC DNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.5"^^xsd:string) "E. coli exonuclease V activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.11.6"^^xsd:string) "E. coli exonuclease VII activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.6"^^xsd:string) "endodeoxyribonuclease VII"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.6"^^xsd:string) "exonuclease VII activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.6"^^xsd:string) "Escherichia coli exonuclease VII"^^xsd:string) AnnotationAssertion(rdfs:label "exodeoxyribonuclease VII activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.6"^^xsd:string) "Catalysis of the exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield 5'-phosphomononucleotides."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.11.6"^^xsd:string) "E. coli exonuclease VII"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.22.5"^^xsd:string) "Escherichia coli endodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.5"^^xsd:string) "Escherichia coli endodeoxyribonuclease X activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.5"^^xsd:string) "Catalysis of the endonucleolytic cleavage of supercoiled plasma DNA to linear DNA duplexes."^^xsd:string) AnnotationAssertion(rdfs:label "exodeoxyribonuclease X activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.22.5"^^xsd:string) "deoxyribonuclease X activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.13.1"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.13.1"^^xsd:string) "RNase II"^^xsd:string) AnnotationAssertion(rdfs:label "exoribonuclease II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.13.1"^^xsd:string) "ribonuclease Q"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.13.1"^^xsd:string) "BN ribonuclease activity"^^xsd:string) AnnotationAssertion( "RNase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.13.1"^^xsd:string) "ribonuclease II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.13.1"^^xsd:string) "5'-exoribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.13.1"^^xsd:string) "Escherichia coli exo-RNase II"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.18.1.3"^^xsd:string) "NADH flavodoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.3"^^xsd:string) "NADH-ferredoxin reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ferredoxin-NAD+ reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.3"^^xsd:string) "ferredoxin-linked NAD reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.3"^^xsd:string) "NADH-ferredoxinTOL reductase (component of toluene dioxygenase)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.3"^^xsd:string) "ferredoxin-nicotinamide adenine dinucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.3"^^xsd:string) "ferredoxin:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.3"^^xsd:string) "NADH2-ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.3"^^xsd:string) "Catalysis of the reaction: reduced ferredoxin + NAD+ = oxidized ferredoxin + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.3"^^xsd:string) "NADH-ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.3"^^xsd:string) "NAD-ferredoxin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.3"^^xsd:string) "reductase, reduced nicotinamide adenine dinucleotide-ferredoxin"^^xsd:string) AnnotationAssertion( "ferredoxin-NAD reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.3"^^xsd:string) "NADH-ferredoxinNAP reductase (component of naphthalene dioxygenase multicomponent enzyme system)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.54"^^xsd:string) "pyruvic formate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.54"^^xsd:string) "formate acetyltransferase activity"^^xsd:string) AnnotationAssertion( "pyruvate formate:lyase activity"^^xsd:string) AnnotationAssertion( "PFL"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.54"^^xsd:string) "pyruvate formate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.54"^^xsd:string) "acetyl-CoA:formate C-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.54"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate."^^xsd:string) AnnotationAssertion(rdfs:label "formate C-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.2"^^xsd:string) "formic acid dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.2"^^xsd:string) "NAD-linked formate dehydrogenase"^^xsd:string) AnnotationAssertion(rdfs:label "formate dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.2"^^xsd:string) "formate hydrogenlyase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.2"^^xsd:string) "formate:NAD+ oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.2"^^xsd:string) "FDH II"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.2"^^xsd:string) "formate-NAD oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.2"^^xsd:string) "formate dehydrogenase (NAD)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.2"^^xsd:string) Annotation( "RHEA:15988"^^xsd:string) "Catalysis of the reaction: formate + NAD(+) = CO(2) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.2"^^xsd:string) "N-FDH"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.2"^^xsd:string) "NAD-formate dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.2"^^xsd:string) "formate benzyl-viologen oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.2"^^xsd:string) "formic hydrogen-lyase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.2"^^xsd:string) "NAD-dependent formate dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.2"^^xsd:string) "FDH I"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.10"^^xsd:string) "formyltetrahydrofolate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.10"^^xsd:string) "formyl-FH(4) hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "formyltetrahydrofolate deformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.10"^^xsd:string) Annotation( "RHEA:19836"^^xsd:string) "Catalysis of the reaction: 10-formyltetrahydrofolate + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + formate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.10"^^xsd:string) "10-formyltetrahydrofolate amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fructokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.4"^^xsd:string) "ATP:D-fructose 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.4"^^xsd:string) "D-fructokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.4"^^xsd:string) "fructokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.4"^^xsd:string) "Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.4"^^xsd:string) "D-fructose(D-mannose)kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.57"^^xsd:string) "D-mannonate:NAD oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.57"^^xsd:string) "mannonic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.57"^^xsd:string) "D-mannonate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.57"^^xsd:string) Annotation( "RHEA:15732"^^xsd:string) "Catalysis of the reaction: D-mannonate + NAD(+) = D-fructuronate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.57"^^xsd:string) "D-mannonate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.57"^^xsd:string) "D-mannonate:NAD+ 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "fructuronate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.57"^^xsd:string) "mannonate oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.42"^^xsd:string) "D-galactarate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.42"^^xsd:string) Annotation( "RHEA:16008"^^xsd:string) "Catalysis of the reaction: galactarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O."^^xsd:string) AnnotationAssertion(rdfs:label "galactarate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.42"^^xsd:string) "D-galactarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.251"^^xsd:string) "galactitol-1-phosphate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactitol-1-phosphate 5-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.251"^^xsd:string) "Catalysis of the reaction: galactitol-1-phosphate + NAD+ = L-tagatose 6-phosphate + NADH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.6"^^xsd:string) "D-galactonate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.6"^^xsd:string) "D-galactonate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.6"^^xsd:string) Annotation( "RHEA:18652"^^xsd:string) "Catalysis of the reaction: D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.6"^^xsd:string) "D-galactonate dehydrase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactonate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.6"^^xsd:string) "D-galactonate hydro-lyase (2-dehydro-3-deoxy-D-galactonate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.18"^^xsd:string) "galactoside acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.18"^^xsd:string) "thiogalactoside transacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.18"^^xsd:string) "acetyl-CoA:beta-D-galactoside 6-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.18"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + a beta-D-galactoside = CoA + a 6-acetyl-beta-D-galactoside."^^xsd:string) AnnotationAssertion(rdfs:label "galactoside O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.18"^^xsd:string) "thiogalactoside acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.46"^^xsd:string) "gentamicin 2''-nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.46"^^xsd:string) "2''-aminoglycoside nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aminoglycoside 2''-nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.46"^^xsd:string) "NTP:gentamicin 2''-nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.46"^^xsd:string) Annotation( "GOC:cb"^^xsd:string) "Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + 2''-nucleotidylaminoglycoside."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.46"^^xsd:string) "gentamycin 2''-nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.46"^^xsd:string) "gentamicin 2''- adenylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucarate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.40"^^xsd:string) "D-glucarate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.40"^^xsd:string) "D-glucarate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.40"^^xsd:string) "Catalysis of the reaction: D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.40"^^xsd:string) "D-glucarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.215"^^xsd:string) "2-keto-D-gluconate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.215"^^xsd:string) "D-gluconate:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.215"^^xsd:string) "Catalysis of the reaction: D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.215"^^xsd:string) "2-ketogluconate reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "gluconate 2-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.69"^^xsd:string) "5-keto-D-gluconate 5-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.69"^^xsd:string) "5-ketogluconate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.69"^^xsd:string) "Catalysis of the reaction: D-gluconate + NADP+ = 5-dehydro-D-gluconate + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.69"^^xsd:string) "5-ketogluconate 5-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.69"^^xsd:string) "5-keto-D-gluconate reductase"^^xsd:string) AnnotationAssertion(rdfs:label "gluconate 5-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.69"^^xsd:string) "D-gluconate:NAD(P)+ 5-oxidoreductase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "gluconate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.215"^^xsd:string) Annotation( "EC:1.1.1.69"^^xsd:string) "Catalysis of the reaction: D-gluconate + NADP+ = dehydro-D-gluconate + NADPH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "quinoprotein glucose dehydrogenase activity"^^xsd:string) AnnotationAssertion( "glucose dehydrogenase (pyrroloquinoline-quinone) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.2"^^xsd:string) "D-glucose:ubiquinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.2"^^xsd:string) "quinoprotein D-glucose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.2"^^xsd:string) "Catalysis of the reaction: D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.2"^^xsd:string) "glucose dehydrogenase (PQQ-dependent) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.2"^^xsd:string) "D-glucose:(pyrroloquinoline-quinone) 1-oxidoreductase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.10"^^xsd:string) "alpha-D-glucose-1-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.10"^^xsd:string) "Catalysis of the reaction: alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "glucose-1-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.10"^^xsd:string) "D-glucose-1-phosphate phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.27"^^xsd:string) "ADP:alpha-D-glucose-1-phosphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.27"^^xsd:string) Annotation( "RHEA:12123"^^xsd:string) "Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = ADP-glucose + diphosphate."^^xsd:string) AnnotationAssertion( "ADPG pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.27"^^xsd:string) "ATP:alpha-D-glucose-1-phosphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.27"^^xsd:string) "ADP glucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.27"^^xsd:string) "glucose 1-phosphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucose-1-phosphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion( "ATP:alpha-glucose-1-phosphate adenylyl transferase activity"^^xsd:string) AnnotationAssertion( "ADGase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.27"^^xsd:string) "adenosine diphosphate glucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.27"^^xsd:string) "adenosine diphosphoglucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.27"^^xsd:string) "ADP-glucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.27"^^xsd:string) "ADP-glucose synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.27"^^xsd:string) "ADP-glucose diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.27"^^xsd:string) "ADP-glucose synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.24"^^xsd:string) "thymidine diphosphoglucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.24"^^xsd:string) "dTDP-glucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.24"^^xsd:string) "dTTP:alpha-D-glucose-1-phosphate thymidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.24"^^xsd:string) "dTDP-glucose diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.24"^^xsd:string) "glucose 1-phosphate thymidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.24"^^xsd:string) "dTDP-glucose synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.24"^^xsd:string) "thymidine diphosphate glucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.24"^^xsd:string) "TDP-glucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.24"^^xsd:string) Annotation( "RHEA:15228"^^xsd:string) "Catalysis of the reaction: alpha-D-glucose 1-phosphate + dTTP = diphosphate + dTDP-glucose."^^xsd:string) AnnotationAssertion(rdfs:label "glucose-1-phosphate thymidylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.1.12"^^xsd:string) "D-glucuronate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.12"^^xsd:string) "uronate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.12"^^xsd:string) "Catalysis of the reaction: D-glucuronate = D-fructuronate."^^xsd:string) AnnotationAssertion(rdfs:label "glucuronate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.12"^^xsd:string) "uronic isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.12"^^xsd:string) "D-glucuronate ketol-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.12"^^xsd:string) "D-glucuronate aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.12"^^xsd:string) "uronic acid isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.1.3"^^xsd:string) Annotation( "RHEA:12816"^^xsd:string) "Catalysis of the reaction: L-glutamate = D-glutamate."^^xsd:string) AnnotationAssertion(rdfs:label "glutamate racemase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.42"^^xsd:string) "ATP:L-glutamate:ammonia ligase (ADP-forming) adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.42"^^xsd:string) "ATP:glutamine synthetase adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.42"^^xsd:string) "glutamine-synthetase adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.42"^^xsd:string) "adenosine triphosphate:glutamine synthetase adenylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[glutamate-ammonia-ligase] adenylyltransferase activity"^^xsd:string) AnnotationAssertion( "glutamate-ammonia-ligase adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.42"^^xsd:string) "Catalysis of the reaction: ATP + [L-glutamate:ammonia ligase (ADP-forming)] = diphosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]."^^xsd:string) AnnotationAssertion( "ATP:[glutamate-ammonia-ligase] adenylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutamyl-tRNA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.70"^^xsd:string) "L-glutamate-semialdehyde: NADP+ oxidoreductase (L-glutamyl-tRNAGlu-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.70"^^xsd:string) Annotation( "RHEA:12347"^^xsd:string) "Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.78"^^xsd:string) "Catalysis of the reaction: N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + H2O = gamma-L-glutamyl-L-cysteinyl-glycine + spermidine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.78"^^xsd:string) "glutathionylspermidine amidohydrolase (spermidine-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.78"^^xsd:string) "gamma-L-glutamyl-L-cysteinyl-glycine:spermidine amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.78"^^xsd:string) "GSP amidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutathionylspermidine amidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.1.8"^^xsd:string) "gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.8"^^xsd:string) "glutathione:spermidine ligase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.8"^^xsd:string) "GSP synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutathionylspermidine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.8"^^xsd:string) "Catalysis of the reaction: gamma-L-glutamyl-L-cysteinyl-glycine + spermidine + ATP = N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.8"^^xsd:string) "glutathionylspermidine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.8"^^xsd:string) "gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming) [spermidine is numbered so that atom N-1 is in the amino group of the aminopropyl part of the molecule]"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glyceraldehyde-3-phosphate dehydrogenase (NADP)"^^xsd:string) AnnotationAssertion( "glyceraldehyde phosphate dehydrogenase (NADP)"^^xsd:string) AnnotationAssertion(rdfs:label "glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity"^^xsd:string) AnnotationAssertion( "glyceraldehyde 3-phosphate dehydrogenase (NADP)"^^xsd:string) AnnotationAssertion( "dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate)"^^xsd:string) AnnotationAssertion( "nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion( "D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion( "glyceraldehyde-3-phosphate:NADP reductase activity"^^xsd:string) AnnotationAssertion( "NADP-glyceraldehyde phosphate dehydrogenase"^^xsd:string) AnnotationAssertion( "NADP-glyceraldehyde-3-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.9"^^xsd:string) Annotation( "RHEA:14672"^^xsd:string) "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(2)O + NADP(+) = 3-phospho-D-glycerate + 2 H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.9"^^xsd:string) "triosephosphate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.31"^^xsd:string) "glycerate-3-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.31"^^xsd:string) "ATP:(R)-glycerate 3-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycerate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.31"^^xsd:string) "glycerate kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.31"^^xsd:string) "D-glycerate 3-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.31"^^xsd:string) "D-glycerate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.31"^^xsd:string) Annotation( "RHEA:23519"^^xsd:string) "Catalysis of the reaction: D-glycerate + ATP = 3-phospho-D-glycerate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.31"^^xsd:string) "D-glyceric acid kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.31"^^xsd:string) "GK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.31"^^xsd:string) "ATP:D-glycerate 2-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.6"^^xsd:string) "NAD-linked glycerol dehydrogenase activity"^^xsd:string) AnnotationAssertion( "glycerol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.6"^^xsd:string) Annotation( "RHEA:13772"^^xsd:string) "Catalysis of the reaction: glycerol + NAD(+) = glycerone + H(+) + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "glycerol dehydrogenase [NAD+] activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.46"^^xsd:string) "gene hpd protein"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.46"^^xsd:string) "glycerophosphoryl diester phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.46"^^xsd:string) "glycerophosphodiester glycerophosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycerophosphodiester phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.46"^^xsd:string) "IgD-binding protein D"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.46"^^xsd:string) "Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.29"^^xsd:string) "2-amino-3-ketobutyrate-CoA ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycine C-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.29"^^xsd:string) Annotation( "RHEA:20739"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + glycine = L-2-amino-3-oxobutanoate + CoA + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.29"^^xsd:string) "aminoacetone synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.29"^^xsd:string) "2-amino-3-ketobutyrate CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.29"^^xsd:string) "acetyl-CoA:glycine C-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.29"^^xsd:string) "2-amino-3-ketobutyrate coenzyme A ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.29"^^xsd:string) "glycine acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "Catalysis of the reaction: glycolate + O2 = glyoxylate + hydrogen peroxide."^^xsd:string) AnnotationAssertion(rdfs:label "glycolate oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.3"^^xsd:string) "guanine aminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.3"^^xsd:string) "guanase activity"^^xsd:string) AnnotationAssertion(rdfs:label "guanine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.3"^^xsd:string) "Catalysis of the reaction: guanine + H2O = xanthine + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.3"^^xsd:string) "guanine aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.3"^^xsd:string) "GAH activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.7.2"^^xsd:string) "PpGpp phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.7.2"^^xsd:string) "Catalysis of the reaction: guanosine 3',5'-bis(diphosphate) + H2O = guanosine 5'-diphosphate + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.7.2"^^xsd:string) "(ppGpp)ase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.7.2"^^xsd:string) "penta-phosphate guanosine-3'-diphosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.7.2"^^xsd:string) "guanosine-3',5'-bis(diphosphate) 3'-pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.7.2"^^xsd:string) "PpGpp-3'-pyrophosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.7.2"^^xsd:string) "penta-phosphate guanosine-3'-pyrophosphohydrolase activity"^^xsd:string) AnnotationAssertion( "guanosine-3',5'-bis(diphosphate) 3'-diphosphohydrolase activity"^^xsd:string) AnnotationAssertion( "guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.40"^^xsd:string) "guanosine 5'-triphosphate-3'-diphosphate 5'-phosphohydrolase activity"^^xsd:string) AnnotationAssertion( "guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.40"^^xsd:string) "Catalysis of the reaction: guanosine 5'-triphosphate,3'-diphosphate + H2O = guanosine 5'-diphosphate,3'-diphosphate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.40"^^xsd:string) "guanosine-5'-triphosphate,3'-diphosphate 5'-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.40"^^xsd:string) "pppGpp 5'-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.40"^^xsd:string) "guanosine 5'-triphosphate 3'-diphosphate 5'-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.40"^^xsd:string) "guanosine pentaphosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.40"^^xsd:string) "guanosine pentaphosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.40"^^xsd:string) "guanosine pentaphosphate phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phosphopantetheinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) "ACPS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) "P-pant transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) "4'-phosphopantetheinyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) "holo-ACP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) "acyl carrier protein holoprotein (holo-ACP) synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) "holosynthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) "AcpS"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) "CoA:apo-acyl-carrier-protein pantetheinephosphotransferase activity"^^xsd:string) AnnotationAssertion( "holo-[acyl-carrier-protein] synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) "alphaaminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) "PPTase activity"^^xsd:string) AnnotationAssertion( "4'-phosphopantetheinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) "acyl carrier protein synthetase activity"^^xsd:string) AnnotationAssertion( "holo-[peptidyl-carrier protein] synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "holo-[acyl-carrier-protein] synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) "holo-ACP synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) "acyl carrier protein synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) "CoA-[4'-phosphopantetheine]:apo-acyl-carrier-protein 4'-pantetheinephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) "coenzyme A:fatty acid synthetase apoenzyme 4'-phosphopantetheine transferase activity"^^xsd:string) AnnotationAssertion( "alpha-aminoadipate reductase phosphopantetheinyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) "alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) "holo-acyl-carrier-protein synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.7"^^xsd:string) Annotation( "PMID:10320345"^^xsd:string) Annotation( "PMID:11867633"^^xsd:string) Annotation( "PMID:8939709"^^xsd:string) "Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.10"^^xsd:string) "S-adenosylmethionine:homocysteine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.10"^^xsd:string) "homocysteine transmethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.10"^^xsd:string) "methylmethionine:homocysteine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.10"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + L-homocysteine = S-adenosyl-L-homocysteine + L-methionine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.10"^^xsd:string) "S-methylmethionine homocysteine transmethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.10"^^xsd:string) "homocysteine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.10"^^xsd:string) "S-adenosyl-L-methionine:L-homocysteine S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.10"^^xsd:string) "S-adenosylmethionine homocysteine transmethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.10"^^xsd:string) "S-adenosyl-L-methionine:L-homocysteine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.10"^^xsd:string) "S-adenosylmethionine-homocysteine transmethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.10"^^xsd:string) "adenosylmethionine transmethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.10"^^xsd:string) "adenosylmethionine:homocysteine methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "homocysteine S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.10"^^xsd:string) "L-homocysteine S-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.46"^^xsd:string) "homoserine succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.46"^^xsd:string) "homoserine O-transsuccinylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "homoserine O-succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.46"^^xsd:string) "succinyl-CoA:L-homoserine O-succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.46"^^xsd:string) Annotation( "RHEA:22011"^^xsd:string) "Catalysis of the reaction: L-homoserine + succinyl-CoA = O-succinyl-L-homoserine + CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.10"^^xsd:string) "H(+)/K(+)-exchanging ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.10"^^xsd:string) "gastric H+/K+ ATPase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.10"^^xsd:string) "H+/K+-exchanging ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.10"^^xsd:string) "proton pump activity"^^xsd:string) AnnotationAssertion( "hydrogen:potassium exchanging ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.10"^^xsd:string) "H+-K+-ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.10"^^xsd:string) "(K+ + H+)-ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.10"^^xsd:string) "ATP phosphohydrolase (H+/K+-exchanging)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.10"^^xsd:string) "H+/K+-ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.10"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "hydrogen:potassium-exchanging ATPase activity"^^xsd:string) AnnotationAssertion( "hydrogen/potassium-exchanging ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.10"^^xsd:string) "H(+)/K(+)-ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.10"^^xsd:string) "gastric H(+)/K(+) ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.10"^^xsd:string) "H,K-ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "H2 oxidizing hydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.7.2"^^xsd:string) "hydrogenase (ferredoxin) activity"^^xsd:string) AnnotationAssertion(rdfs:label "ferredoxin hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.7.2"^^xsd:string) "Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2."^^xsd:string) AnnotationAssertion( "iron hydrogenase activity"^^xsd:string) AnnotationAssertion( "hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.7.2"^^xsd:string) "bidirectional hydrogenase activity"^^xsd:string) AnnotationAssertion( "H2 producing hydrogenase"^^xsd:string) AnnotationAssertion( "Ni-Fe-Se hydrogenase activity"^^xsd:string) AnnotationAssertion( "hydrogenase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.7.2"^^xsd:string) "uptake hydrogenase activity"^^xsd:string) AnnotationAssertion( "[Fe] hydrogenase gamma"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.7.2"^^xsd:string) "hydrogen-lyase activity"^^xsd:string) AnnotationAssertion( "hydrogenase I"^^xsd:string) AnnotationAssertion( "hydrogen:ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion( "nickel hydrogenase activity"^^xsd:string) AnnotationAssertion( "iron-only hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.7.2"^^xsd:string) "hydrogenlyase activity"^^xsd:string) AnnotationAssertion( "nickel-iron hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.7.2"^^xsd:string) "H(2) producing hydrogenase activity"^^xsd:string) AnnotationAssertion( "Ni-Fe hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.7.2"^^xsd:string) "H(2) oxidizing hydrogenase activity"^^xsd:string) AnnotationAssertion( "[Fe] hydrogenase activity"^^xsd:string) AnnotationAssertion( "nickel-iron-selenium hydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.49"^^xsd:string) "hydroxymethylpyrimidine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "hydroxymethylpyrimidine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.49"^^xsd:string) "ATP:4-amino-5-hydroxymethyl-2-methylpyrimidine 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.49"^^xsd:string) Annotation( "RHEA:23099"^^xsd:string) "Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + 2 H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.1.22"^^xsd:string) "hydroxypyruvate ketol-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.22"^^xsd:string) "hydroxypyruvate aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.22"^^xsd:string) Annotation( "RHEA:11955"^^xsd:string) "Catalysis of the reaction: 3-hydroxypyruvate = 2-hydroxy-3-oxopropanoate."^^xsd:string) AnnotationAssertion(rdfs:label "hydroxypyruvate isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "hygromycin-B kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.119"^^xsd:string) "ATP:hygromycin-B 7''-O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hygromycin-B 7''-O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.119"^^xsd:string) Annotation( "RHEA:23391"^^xsd:string) "Catalysis of the reaction: ATP + hygromycin B = 7''-O-phosphohygromycin B + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.119"^^xsd:string) "hygromycin B phosphotransferase activity"^^xsd:string) AnnotationAssertion( "destomic acid ring 7''-O-phosphotransferase activity"^^xsd:string) AnnotationAssertion( "hygromycin B kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.119"^^xsd:string) "APH(7'') activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a phosphate group from GTP or GDP to a mannose molecule."^^xsd:string) AnnotationAssertion(rdfs:label "mannose-phosphate guanylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.73"^^xsd:string) "inosine-guanosine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.73"^^xsd:string) "inosine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.73"^^xsd:string) "ATP:inosine 5'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inosine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.73"^^xsd:string) "Catalysis of the reaction: ATP + inosine = ADP + IMP."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the integration of one segment of DNA into another."^^xsd:string) AnnotationAssertion(rdfs:label "integrase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.3.2.1"^^xsd:string) "2,3-dihydro-2,3-dihydroxybenzoate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.1"^^xsd:string) "2,3 dihydro-2,3 dihydroxybenzoate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "isochorismatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.1"^^xsd:string) "2,3-dihydroxy-2,3-dihydrobenzoate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.1"^^xsd:string) Annotation( "RHEA:11115"^^xsd:string) "Catalysis of the reaction: H(2)O + isochorismate = 2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.1"^^xsd:string) "2,3-dihydroxy-2,3-dihydrobenzoic synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.1"^^xsd:string) "isochorismate pyruvate-hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.4.2"^^xsd:string) "isochorismate hydroxymutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.4.2"^^xsd:string) Annotation( "RHEA:18988"^^xsd:string) "Catalysis of the reaction: chorismate = isochorismate."^^xsd:string) AnnotationAssertion(rdfs:label "isochorismate synthase activity"^^xsd:string) AnnotationAssertion( "isochorismate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.4.2"^^xsd:string) "isochorismate synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.95"^^xsd:string) Annotation( "RHEA:24259"^^xsd:string) "Catalysis of the reaction: ATP + kanamycin = ADP + 2 H(+) + kanamycin 3'-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.95"^^xsd:string) "neomycin phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.95"^^xsd:string) "kanamycin kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.95"^^xsd:string) "ATP:kanamycin 3'-O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "kanamycin kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.95"^^xsd:string) "APH(3') activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.95"^^xsd:string) "neomycin-kanamycin phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.95"^^xsd:string) "aminoglycoside 3'-phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.22"^^xsd:string) "(S)-lactaldehyde:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.22"^^xsd:string) "Catalysis of the reaction: (S)-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.22"^^xsd:string) "L-lactaldehyde:NAD oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.22"^^xsd:string) "nicotinamide adenine dinucleotide (NAD)-linked dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lactaldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.77"^^xsd:string) "(R)- or (S)-propane-1,2-diol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.77"^^xsd:string) "propanediol oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.77"^^xsd:string) "Catalysis of the reaction: propane-1,2-diol + NAD+ = lactaldehyde + NADH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "lactaldehyde reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.77"^^xsd:string) "propanediol:nicotinamide adenine dinucleotide (NAD) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.77"^^xsd:string) "lactaldehyde:propanediol oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lauroyltransferase activity"^^xsd:string) AnnotationAssertion( "lauroyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of a lauroyl (dodecanoyl) group from one compound to another."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "leucyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.6"^^xsd:string) "L-leucyl-tRNA:protein leucyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.6"^^xsd:string) "leucyl/phenylalanyl-tRNA--protein transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.6"^^xsd:string) "leucyl, phenylalanine-tRNA-protein transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.6"^^xsd:string) "leucyl-tRNA--protein transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.6"^^xsd:string) "leucyl-phenylalanine-transfer ribonucleate-protein transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.6"^^xsd:string) "Catalysis of the reaction: L-leucyl-tRNA + protein = tRNA + L-leucyl-protein."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.6"^^xsd:string) "L/F transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.6"^^xsd:string) "leucyl-phenylalanine-transfer ribonucleate-protein aminoacyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lipid-A-disaccharide synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.182"^^xsd:string) "UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine:2,3-bis-(3-hydroxytetradecanoyl)-beta-D-glucosaminyl-1-phosphate 2,3-bis(3-hydroxytetradecanoyl)-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.182"^^xsd:string) Annotation( "RHEA:22671"^^xsd:string) "Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine = 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + H(+) + UDP."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.56"^^xsd:string) "uridine diphosphoacetylglucosamine-lipopolysaccharide acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion( "LPS N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.56"^^xsd:string) "UDP-N-acetyl-D-glucosamine:lipopolysaccharide N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.56"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lipopolysaccharide = UDP + N-acetyl-D-glucosaminyl-lipopolysaccharide."^^xsd:string) AnnotationAssertion(rdfs:label "lipopolysaccharide N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.56"^^xsd:string) "UDP-N-acetylglucosamine-lipopolysaccharide N-acetylglucosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "lipopolysaccharide galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.44"^^xsd:string) "Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,3 alpha-D-galactosyl-lipopolysaccharide."^^xsd:string) AnnotationAssertion( "LPS 3-alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.44"^^xsd:string) "uridine diphosphate galactose:lipopolysaccharide alpha-3-galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "lipopolysaccharide-alpha-1,3-D-galactosyltransferase"^^xsd:string) AnnotationAssertion(rdfs:label "lipopolysaccharide 3-alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.44"^^xsd:string) "UDPgalactose:lipopolysaccharide 3-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.44"^^xsd:string) "lipopolysaccharide 1,3-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.44"^^xsd:string) "UDP-galactose:lipopolysaccharide 3-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.44"^^xsd:string) "UDP-galactose:polysaccharide galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.44"^^xsd:string) "UDP-galactose:lipopolysaccharide alpha,3-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.44"^^xsd:string) "uridine diphosphogalactose-lipopolysaccharide alpha,3-galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.58"^^xsd:string) "lipopolysaccharide glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.58"^^xsd:string) "Catalysis of the reaction: UDP-glucose + lipopolysaccharide = UDP + D-glucosyl-lipopolysaccharide."^^xsd:string) AnnotationAssertion( "LPS glucosyltransferase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.58"^^xsd:string) "UDPglucose:lipopolysaccharide glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.58"^^xsd:string) "uridine diphosphate glucose:lipopolysaccharide glucosyltransferase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.58"^^xsd:string) "UDPglucose:lipopolysaccharide glucosyltransferase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.58"^^xsd:string) "uridine diphosphoglucose-lipopolysaccharide glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lipopolysaccharide glucosyltransferase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.58"^^xsd:string) "UDP-glucose:lipopolysaccharide glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "LPS heptosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lipopolysaccharide heptosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-5061"^^xsd:string) Annotation( "MetaCyc:RXN0-5122"^^xsd:string) Annotation( "MetaCyc:RXN0-5127"^^xsd:string) "Catalysis of the reaction: a lipopolysaccharide + ADP-L-glycero-beta-D-manno-heptose = a heptosylated lipopolysaccharide + ADP + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,6 alpha-D-galactosyl-lipopolysaccharide."^^xsd:string) AnnotationAssertion(rdfs:label "lipopolysaccharide-1,6-galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "LPS-1,6-galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.20"^^xsd:string) "long-chain-fatty-acid:acyl-carrier-protein ligase (AMP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.20"^^xsd:string) "acyl-acyl-carrier-proteinsynthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.20"^^xsd:string) "stearoyl-ACP synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15904"^^xsd:string) Annotation( "EC:6.2.1.20"^^xsd:string) "Catalysis of the reaction: ATP + an acid + [acyl-carrier protein] = AMP + diphosphate + acyl-[acyl-carrier protein]. A long-chain fatty acid is fatty acid with a chain length between C13 and C22."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.20"^^xsd:string) "acyl-acyl carrier protein synthetase"^^xsd:string) AnnotationAssertion( "acyl-ACP synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.20"^^xsd:string) "acyl-[acyl-carrier-protein] synthetase activity"^^xsd:string) AnnotationAssertion( "long-chain fatty acid-[acyl-carrier-protein] ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.20"^^xsd:string) "long-chain-fatty-acid-acyl-carrier-protein ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.20"^^xsd:string) "acyl-acyl-carrier-protein synthetase activity"^^xsd:string) AnnotationAssertion( "long-chain-fatty-acid-[acyl-carrier-protein] ligase activity"^^xsd:string) AnnotationAssertion( "long-chain-fatty-acid-ACP ligase activity"^^xsd:string) AnnotationAssertion( "long-chain-fatty-acid-[acyl-carrier protein] ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "long-chain fatty acid [acyl-carrier-protein] ligase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.18"^^xsd:string) "L-lysine carboxy-lyase (cadaverine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.18"^^xsd:string) Annotation( "RHEA:22355"^^xsd:string) "Catalysis of the reaction: L-lysine + H(+) = cadaverine + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.18"^^xsd:string) "L-lysine carboxy-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lysine decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:MALATE-DEHYDROGENASE-ACCEPTOR-RXN"^^xsd:string) "Catalysis of the reaction: (S)-malate + a quinone = oxaloacetate + a quinol."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.4"^^xsd:string) "FAD-dependent malate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.4"^^xsd:string) "(S)-malate:quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.4"^^xsd:string) "MQO activity"^^xsd:string) AnnotationAssertion(rdfs:label "malate dehydrogenase (quinone) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.4"^^xsd:string) "(S)-malate:(quinone) oxidoreductase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.79"^^xsd:string) "acetyl-CoA:maltose O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.79"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + maltose = CoA + acetyl-maltose."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.79"^^xsd:string) "maltose transacetylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "maltose O-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mannitol-1-phosphate 5-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.17"^^xsd:string) "Catalysis of the reaction: D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.8"^^xsd:string) Annotation( "RHEA:20100"^^xsd:string) "Catalysis of the reaction: D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.8"^^xsd:string) "altronic hydro-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannonate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.8"^^xsd:string) "D-mannonate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.8"^^xsd:string) "D-mannonate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.8"^^xsd:string) "mannonic hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.8"^^xsd:string) "mannonate hydrolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.8"^^xsd:string) "D-mannonate hydrolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.8"^^xsd:string) "altronate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.22"^^xsd:string) "GDP-mannose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion( "GDP:mannose-1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.22"^^xsd:string) "GDP-mannose 1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.22"^^xsd:string) "mannose 1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.22"^^xsd:string) "GDP:alpha-D-mannose-1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannose-1-phosphate guanylyltransferase (GDP) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.22"^^xsd:string) "GDP mannose phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.22"^^xsd:string) "guanosine diphosphate-mannose 1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.22"^^xsd:string) "GDP:D-mannose-1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.22"^^xsd:string) "guanosine diphosphomannose phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.22"^^xsd:string) Annotation( "RHEA:12908"^^xsd:string) "Catalysis of the reaction: alpha-D-mannose 1-phosphate + GDP + H(+) = GDP-alpha-D-mannose + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.22"^^xsd:string) "GDP-mannose phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.22"^^xsd:string) "mannose 1-phosphate (guanosine diphosphate) guanylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.3"^^xsd:string) "methylglyoxal synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.3"^^xsd:string) "glycerone-phosphate phospho-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.3"^^xsd:string) "glycerone-phosphate phospho-lyase (methylglyoxal-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "methylglyoxal synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.3"^^xsd:string) Annotation( "RHEA:17940"^^xsd:string) "Catalysis of the reaction: glycerone phosphate = methylglyoxal + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.16"^^xsd:string) "5'-methylthioadenosine nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.16"^^xsd:string) "MeSAdo nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.16"^^xsd:string) "methylthioadenosine methylthioribohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.16"^^xsd:string) "S-methyl-5'-thioadenosine adeninehyrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.16"^^xsd:string) "MTA nucleosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methylthioadenosine nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.16"^^xsd:string) "Catalysis of the reaction: methylthioadenosine + H2O = adenine + 5-methylthio-D-ribose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "murein lytic endotransglycosylase E activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10964424"^^xsd:string) Annotation( "PMID:9642199"^^xsd:string) "Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. Acts on linkages within peptidoglycan chains (i.e. not at the ends) to produce shorter strands with 1,6-anhydromuramic acid ends."^^xsd:string) AnnotationAssertion(rdfs:label "lytic endotransglycosylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "peptidoglycan lytic transglycosylase activity"^^xsd:string) AnnotationAssertion( "murein transglycosylase B activity"^^xsd:string) AnnotationAssertion(rdfs:label "lytic transglycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10964424"^^xsd:string) "Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "L-myo-inositol-1-phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "Catalysis of the reaction: myo-inositol 1-phosphate + H2O = myo-inositol + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "inositol monophosphate 1-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "myo-inositol-1(or 4)-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "myo-inositol 1-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "inositol 1-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "myo-inositol-1-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "inositol-1(or 4)-monophosphatase activity"^^xsd:string) AnnotationAssertion( "myo-inositol-1(or 4)-monophosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "KEGG:R04150"^^xsd:string) "O-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.36"^^xsd:string) "dihydroxynaphthoic acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.36"^^xsd:string) "O-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.36"^^xsd:string) "O-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing; CoA-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.36"^^xsd:string) "DHNA synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1,4-dihydroxy-2-naphthoyl-CoA synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.36"^^xsd:string) "Catalysis of the reaction: O-succinylbenzoyl-CoA = 1,4-dihydroxy-2-naphthoate + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.36"^^xsd:string) "1,4-dihydroxy-2-naphthoate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.36"^^xsd:string) "dihydroxynaphthoate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nicotinamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.19"^^xsd:string) "nicotine deamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.19"^^xsd:string) "YNDase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.19"^^xsd:string) "nicotinamide amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.19"^^xsd:string) "Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.19"^^xsd:string) "nicotinamide deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.19"^^xsd:string) "NAMase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.19"^^xsd:string) "nicotinamide amidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.18.1.-"^^xsd:string) "Catalysis of the reaction: reduced ferredoxin + NAD(P)+ = oxidized ferredoxin + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(rdfs:label "ferredoxin-NAD(P) reductase activity"^^xsd:string) AnnotationAssertion( "ferredoxin reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.7"^^xsd:string) "S-adenosyl-L-methionine:nicotinate N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.7"^^xsd:string) Annotation( "RHEA:20244"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinate = N-methylnicotinate + S-adenosyl-L-homocysteine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.7"^^xsd:string) "furanocoumarin 8-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nicotinate N-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.21"^^xsd:string) "nicotinate-nucleotide:5,6-dimethylbenzimidazole phospho-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.21"^^xsd:string) "N1-alpha-phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.21"^^xsd:string) "nicotinate ribonucleotide:benzimidazole (adenine) phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.21"^^xsd:string) "CobT"^^xsd:string) AnnotationAssertion(rdfs:label "nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.21"^^xsd:string) "N(1)-alpha-phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.21"^^xsd:string) "nicotinate mononucleotide-dimethylbenzimidazole phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.21"^^xsd:string) Annotation( "RHEA:11199"^^xsd:string) "Catalysis of the reaction: 5,6-dimethylbenzimidazole + nicotinate D-ribonucleotide = alpha-ribazole 5'-phosphate + H(+) + nicotinate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.21"^^xsd:string) "nicotinate mononucleotide (NaMN):5,6-dimethylbenzimidazole phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.21"^^xsd:string) "nicotinate-nucleotide:dimethylbenzimidazole phospho-D-ribosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.99.4"^^xsd:string) "nitrite:(acceptor) oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.99.4"^^xsd:string) "nitrate reductase (acceptor)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.99.4"^^xsd:string) "Catalysis of the reaction: nitrite + acceptor = nitrate + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.99.4"^^xsd:string) "nitrite:acceptor oxidoreductase"^^xsd:string) AnnotationAssertion(rdfs:label "nitrate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.99.4"^^xsd:string) "respiratory nitrate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.12.17"^^xsd:string) "nitric oxide,NAD(P)H:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.17"^^xsd:string) "Catalysis of the reaction: 2 NO + 2 O2 + NADPH + H+ = 2 nitrate + NADP+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.17"^^xsd:string) "NOD activity"^^xsd:string) AnnotationAssertion(rdfs:label "nitric oxide dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.1.4"^^xsd:string) "nitrite reductase (reduced nicotinamide adenine dinucleotide (phosphate)) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.4"^^xsd:string) "nitrite reductase [NAD(P)H2]"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.4"^^xsd:string) "NADPH-nitrite reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nitrite reductase [NAD(P)H] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.4"^^xsd:string) "assimilatory nitrite reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.4"^^xsd:string) "Catalysis of the reaction: ammonium hydroxide + 3 NAD(P)+ + H2O = nitrite + 3 NAD(P)H + 3 H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.4"^^xsd:string) "ammonium-hydroxide:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.4"^^xsd:string) "NAD(P)H2:nitrite oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.4"^^xsd:string) "NADH-nitrite oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.4"^^xsd:string) "NAD(P)H:nitrite oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.13.3"^^xsd:string) "Catalysis of the exonucleolytic cleavage of oligonucleotides to yield nucleoside 5'-phosphates."^^xsd:string) AnnotationAssertion(rdfs:label "oligonucleotidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.3"^^xsd:string) "oxaloacetate carboxy-lyase (pyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.38"^^xsd:string) Annotation( "EC:1.1.1.40"^^xsd:string) Annotation( "EC:4.1.1.3"^^xsd:string) "Catalysis of the reaction: oxaloacetate = pyruvate + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.3"^^xsd:string) "oxalacetic acid decarboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oxaloacetate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.3"^^xsd:string) "oxalate beta-decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.3"^^xsd:string) "oxaloacetate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.3"^^xsd:string) "oxaloacetate beta-decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.8"^^xsd:string) "oxalyl-CoA carboxy-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oxalyl-CoA decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.8"^^xsd:string) Annotation( "RHEA:19336"^^xsd:string) "Catalysis of the reaction: H(+) + oxalyl-CoA = CO(2) + formyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.8"^^xsd:string) "oxalyl-CoA carboxy-lyase (formyl-CoA-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.8"^^xsd:string) "oxalyl coenzyme A decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:PALMITOTRANS-RXN"^^xsd:string) "Catalysis of the reaction: a palmitoleoyl-[acyl-carrier protein] + alpha-KDO-(2->4)-alpha-KDO-(2->6)-lipid IVA = KDO2-(palmitoleoyl)-lipid IVA + a holo-[acyl-carrier protein]."^^xsd:string) AnnotationAssertion(rdfs:label "palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity"^^xsd:string) AnnotationAssertion( "palmitoleoyl ACP-dependent acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.11"^^xsd:string) "ampicillin acylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.11"^^xsd:string) "alpha-acylamino-beta-lactam acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.11"^^xsd:string) "novozym 217"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.11"^^xsd:string) "Catalysis of the reaction: penicillin + H2O = a carboxylate + 6-aminopenicillanate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.11"^^xsd:string) "semacylase activity"^^xsd:string) AnnotationAssertion( "palmitoleoyl [acyl-carrier protein]-dependent acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "penicillin amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.11"^^xsd:string) "penicillin acylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.11"^^xsd:string) "benzylpenicillin acylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.11"^^xsd:string) "penicillin amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.129"^^xsd:string) "penicillin binding protein (3 or 1B) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.129"^^xsd:string) "peptidoglycan TGase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.129"^^xsd:string) "undecaprenyldiphospho-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.129"^^xsd:string) "PG-II activity"^^xsd:string) AnnotationAssertion(rdfs:label "peptidoglycan glycosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.129"^^xsd:string) "peptidoglycan transglycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.129"^^xsd:string) "Catalysis of the reaction: [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphosphoundecaprenol + GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphosphoundecaprenol + undecaprenyl diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.129"^^xsd:string) "bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.39"^^xsd:string) "phenylacetaldehyde:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phenylacetaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.39"^^xsd:string) "Catalysis of the reaction: phenylacetaldehyde + NAD+ + H2O = phenylacetate + NADH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphate acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.8"^^xsd:string) "PTA"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.8"^^xsd:string) "acetyl-CoA:phosphate acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.8"^^xsd:string) "phosphotransacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.8"^^xsd:string) "phosphoacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.8"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + phosphate = CoA + acetyl phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.20"^^xsd:string) "phosphoglycerol transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.20"^^xsd:string) "Catalysis of the reaction: phosphatidylglycerol + membrane-derived-oligosaccharide D-glucose = 1,2-diacyl-sn-glycerol + membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.20"^^xsd:string) "phosphoglycerol transferase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.20"^^xsd:string) "oligosaccharide glycerophosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.20"^^xsd:string) "phosphatidylglycerol:membrane-derived-oligosaccharide-D-glucose glycerophosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8051048"^^xsd:string) "Catalysis of the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the prospective N-terminal cysteine residue in an unmodified prolipoprotein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.27"^^xsd:string) "phosphatidylglycerophosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.27"^^xsd:string) "phosphatidylglycerol phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylglycerophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.27"^^xsd:string) "phosphatidylglycerol phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.27"^^xsd:string) "Catalysis of the reaction: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.27"^^xsd:string) "PGP phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.13"^^xsd:string) "UDP-MurNAc-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala:C(55)-isoprenoid alcohol transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.13"^^xsd:string) "MraY transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.13"^^xsd:string) "UDP-MurNAc-pentapeptide phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.13"^^xsd:string) "phosphoacetylmuramoylpentapeptidetransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phospho-N-acetylmuramoyl-pentapeptide-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.13"^^xsd:string) "UDP-MurAc(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala):undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.13"^^xsd:string) "phospho-NAc-muramoyl-pentapeptide translocase (UMP) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.13"^^xsd:string) "Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine-diphosphoundecaprenol."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.13"^^xsd:string) "phosphoacetylmuramoylpentapeptide translocase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.13"^^xsd:string) "phospho-MurNAc-pentapeptide transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.13"^^xsd:string) "phospho-N-acetylmuramoyl pentapeptide translocase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.13"^^xsd:string) "UDP-MurNAc-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala:C55-isoprenoid alcohol transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.13"^^xsd:string) "UDP-MurNAc-Ala-gamma-DGlu-Lys-DAla-DAla:undecaprenylphosphate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.13"^^xsd:string) "UDP-MurNAc-Ala-gammaDGlu-Lys-DAla-DAla:undecaprenylphosphate transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.31"^^xsd:string) "phosphoenolpyruvic carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.31"^^xsd:string) "phosphopyruvate (phosphate) carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.31"^^xsd:string) "phosphate:oxaloacetate carboxy-lyase (adding phosphate; phosphoenolpyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.31"^^xsd:string) "PEPC"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.31"^^xsd:string) "Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + HCO3-."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.31"^^xsd:string) "phosphate:oxaloacetate carboxy-lyase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.31"^^xsd:string) "PEP carboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoenolpyruvate carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.31"^^xsd:string) "PEPCase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.3.9"^^xsd:string) "phosphopyruvate--protein phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.9"^^xsd:string) "phosphopyruvate--protein factor phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.9"^^xsd:string) "Catalysis of the reaction: phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)-phospho-L-histidine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.9"^^xsd:string) "phosphoenolpyruvate sugar phosphotransferase enzyme I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.9"^^xsd:string) "enzyme I of the phosphotransferase system"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.9"^^xsd:string) "phosphoenolpyruvate:protein-L-histidine Npi-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoenolpyruvate-protein phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.9"^^xsd:string) "sugar--PEP phosphotransferase enzyme I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.9"^^xsd:string) "phosphoenolpyruvate--protein phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.9"^^xsd:string) "phosphoenolpyruvate:protein-L-histidine N-pros-phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.2.10"^^xsd:string) Annotation( "RHEA:23427"^^xsd:string) "Catalysis of the reaction: alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.10"^^xsd:string) "alpha-D-glucosamine 1,6-phosphomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.10"^^xsd:string) "D-glucosamine 1,6-phosphomutase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoglucosamine mutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.18"^^xsd:string) Annotation( "RHEA:14372"^^xsd:string) "Catalysis of the reaction: 2-phosphoglycolate + H(2)O = glycolate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.18"^^xsd:string) "2-phosphoglycolate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.18"^^xsd:string) "P-glycolate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.18"^^xsd:string) "phosphoglycolate hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoglycolate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.18"^^xsd:string) "phosphoglycollate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.18"^^xsd:string) "2-phosphoglycolate phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-sedoheptulose 7-phosphate isomerase activity"^^xsd:string) AnnotationAssertion( "phosphoheptose isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-4301"^^xsd:string) Annotation( "PMID:11279237"^^xsd:string) Annotation( "PMID:8631969"^^xsd:string) "Catalysis of the reaction: D-sedoheptulose-7-phosphate = D-alpha,beta-D-heptose 7-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: phosphohistidine + H2O = histidine + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "phosphohistidine phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.32"^^xsd:string) "Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.32"^^xsd:string) "phospholipase A1 activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylcholine 1-acylhydrolase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.4.7"^^xsd:string) "hydroxymethylpyrimidine phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.7"^^xsd:string) "ATP:4-amino-2-methyl-5-phosphomethylpyrimidine phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphomethylpyrimidine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.7"^^xsd:string) "Catalysis of the reaction: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4-amino-2-methyl-5-diphosphomethylpyrimidine."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.2.7"^^xsd:string) "D-ribose 1,5-phosphomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.7"^^xsd:string) "alpha-D-ribose 1,5-phosphomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.7"^^xsd:string) "phosphodeoxyribomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.7"^^xsd:string) "deoxyribomutase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphopentomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.7"^^xsd:string) "deoxyribose phosphomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.7"^^xsd:string) "alpha-D-glucose-1,6-bisphosphate:deoxy-D-ribose-1-phosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.7"^^xsd:string) "phosphoribomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.7"^^xsd:string) "Catalysis of the reaction: D-ribose 1-phosphate = D-ribose 5-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.19"^^xsd:string) "5-phosphoribulose kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.19"^^xsd:string) "ATP:D-ribulose-5-phosphate 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoribulokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.19"^^xsd:string) Annotation( "RHEA:19368"^^xsd:string) "Catalysis of the reaction: D-ribulose 5-phosphate + ATP = D-ribulose 1,5-bisphosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.19"^^xsd:string) "ribulose phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.19"^^xsd:string) "PKK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.19"^^xsd:string) "PRuK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.19"^^xsd:string) "phosphoribulokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.19"^^xsd:string) "PRK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.19"^^xsd:string) "phosphopentokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.19"^^xsd:string) "ribulose-5-phosphate kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.4.1"^^xsd:string) "ATP-polyphosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "polyphosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "polyphosphate polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.1"^^xsd:string) "Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.1"^^xsd:string) "ATP:polyphosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.1"^^xsd:string) "polyphosphoric acid kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "prephenate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.12"^^xsd:string) "hydroxyphenylpyruvate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.12"^^xsd:string) "prephenate:NAD+ oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.12"^^xsd:string) "chorismate mutase--prephenate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.12"^^xsd:string) Annotation( "RHEA:13872"^^xsd:string) "Catalysis of the reaction: NAD(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "integrase activity involved in establishment of integrated proviral latency"^^xsd:string) AnnotationAssertion(rdfs:label "prophage integrase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the integration of prophage DNA into a target DNA molecule, usually a bacterial chromosome, via a sequence-specific recombination event which involves the formation of an intasome, a DNA-protein-complex designed for site-specific recombination of the phage and host DNA."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.2.15"^^xsd:string) "Catalysis of the reaction: ATP + propanoate = ADP + propanoyl phosphate."^^xsd:string) AnnotationAssertion( "propanoate kinase activity"^^xsd:string) AnnotationAssertion( "TdcD"^^xsd:string) AnnotationAssertion(rdfs:label "propionate kinase activity"^^xsd:string) AnnotationAssertion( "PduW"^^xsd:string) AnnotationAssertion( "ATP:propanoate phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "enzyme IIl4ac"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "protein-Npi-phospho-L-histidine:sugar Npi-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "PTS transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "protein-Npi-phosphohistidine-sugar phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:4.A.-.-.-"^^xsd:string) Annotation( "http://www.ucs.mun.ca/~n55lrb/general_pts.html"^^xsd:string) "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport."^^xsd:string) AnnotationAssertion(rdfs:label "protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "gene bglC RNA formation factors"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "sucrose phosphotransferase system II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "phosphohistidinoprotein-hexose phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "ribonucleic acid formation factor, gene glC"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "protein-Npi-phospho-L-histidine:sugar N-pros-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "group translocator activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "PTS permease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "phosphohistidinoprotein-hexose phosphotransferase activity"^^xsd:string) AnnotationAssertion( "phosphotransfer-driven group translocator"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "phosphotransferase, phosphohistidinoprotein-hexose activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "PEP--sugar phosphotransferase enzyme II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "protein, specific or class, gene bglC"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "PEP-dependent phosphotransferase enzyme II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "gene glC proteins"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "protein-Npi-phosphohistidine:sugar N-pros-phosphotransferase activity"^^xsd:string) AnnotationAssertion( "protein-Np-phosphohistidine-sugar phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "enzyme II of the phosphotransferase system"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "phosphoprotein factor-hexose phosophotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.69"^^xsd:string) "phosphoenolpyruvate-sugar phosphotransferase enzyme II"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.80"^^xsd:string) "protein methylase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.80"^^xsd:string) "protein carboxymethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.80"^^xsd:string) "methyl-accepting chemotaxis protein methyltransferase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.80"^^xsd:string) "methyl-accepting chemotaxis protein O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.80"^^xsd:string) "protein O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.80"^^xsd:string) "protein carboxyl-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.80"^^xsd:string) "protein carboxymethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.80"^^xsd:string) "S-adenosyl-L-methionine:protein-L-glutamate O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.80"^^xsd:string) "protein carboxylmethyltransferase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.80"^^xsd:string) "MCP methyltransferase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.80"^^xsd:string) "protein(carboxyl)methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-glutamate O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.80"^^xsd:string) "MCP methyltransferase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.80"^^xsd:string) "protein(aspartate)methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.80"^^xsd:string) "protein carboxyl-methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.80"^^xsd:string) "S-adenosylmethionine-glutamyl methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.80"^^xsd:string) "S-adenosylmethionine:protein-carboxyl O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.80"^^xsd:string) Annotation( "RESID:AA0072"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate 5-methyl ester; this reaction is the methylation of peptidyl-L-glutamate to form peptidyl-L-glutamate 5-methyl ester."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.61"^^xsd:string) "protein-L-glutamate-5-O-methyl-ester acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.61"^^xsd:string) Annotation( "RESID:AA0072"^^xsd:string) "Catalysis of the reaction: protein L-glutamate O(5)-methyl ester + H2O = protein L-glutamate + methanol."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.61"^^xsd:string) "methyl-accepting chemotaxis protein methyl-esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.61"^^xsd:string) "protein-L-glutamate-O5-methyl-ester acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.61"^^xsd:string) "chemotaxis-specific methylesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.61"^^xsd:string) "CheB methylesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.61"^^xsd:string) "methylesterase CheB activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-glutamate methylesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.9.2"^^xsd:string) "phosphoenolpyruvic synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.2"^^xsd:string) "PEP synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyruvate, water dikinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.2"^^xsd:string) "phosphopyruvate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.2"^^xsd:string) "pyruvate,water dikinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.2"^^xsd:string) "phosphoenolpyruvate synthase activity"^^xsd:string) AnnotationAssertion( "PEP synthase activity"^^xsd:string) AnnotationAssertion( "water pyruvate dikinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.2"^^xsd:string) "ATP:pyruvate, water phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.2"^^xsd:string) "pyruvate-water dikinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.2"^^xsd:string) "phoephoenolpyruvate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.2"^^xsd:string) Annotation( "RHEA:11367"^^xsd:string) "Catalysis of the reaction: ATP + H(2)O + pyruvate = AMP + 3 H(+) + phosphate + phosphoenolpyruvate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "quinolinate synthetase A activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "MetaCyc:QUINOLINATE-SYNTHA-RXN"^^xsd:string) "Catalysis of the reaction: iminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H2O + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "rRNA (adenine-N6-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.48"^^xsd:string) "S-adenosyl-L-methionine:rRNA (adenine-6-N-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.48"^^xsd:string) "ribonucleic acid-adenine (N6) methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.48"^^xsd:string) "S-adenosyl-L-methionine:rRNA (adenine-N6-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.48"^^xsd:string) "ribonucleic acid-adenine (N(6)) methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.48"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N6-methyladenine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.48"^^xsd:string) "ErmC 23S rRNA methyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.48"^^xsd:string) "ribosomal ribonucleate adenine 6-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.48"^^xsd:string) "gene ksgA methyltransferase"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.51"^^xsd:string) "ribosomal ribonucleate guanine 1-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.51"^^xsd:string) "S-adenosyl-L-methionine:rRNA (guanine-N1-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.51"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N1-methylguanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.51"^^xsd:string) "S-adenosyl-L-methionine:rRNA (guanine-1-N-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "rRNA (guanine-N1-)-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.52"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N2-methylguanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.52"^^xsd:string) "S-adenosyl-L-methionine:rRNA (guanine-N2-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.52"^^xsd:string) "ribosomal ribonucleate guanine-2-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.52"^^xsd:string) "S-adenosyl-L-methionine:rRNA (guanine-2-N-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "rRNA (guanine-N2-)-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.5"^^xsd:string) "RhuK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.5"^^xsd:string) "rhamnulose kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.5"^^xsd:string) "ATP:L-rhamnulose 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.5"^^xsd:string) "L-rhamnulose kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.5"^^xsd:string) "L-rhamnulokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.5"^^xsd:string) "Catalysis of the reaction: ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.5"^^xsd:string) "rhamnulokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "rhamnulokinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.19"^^xsd:string) "Catalysis of the reaction: L-rhamnulose 1-phosphate = glycerone phosphate + (S)-lactaldehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.19"^^xsd:string) "L-rhamnulose-1-phosphate lactaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.19"^^xsd:string) "rhamnulose phosphate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.19"^^xsd:string) "L-rhamnulose-phosphate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.19"^^xsd:string) "L-rhamnulose-1-phosphate S-lactaldehyde-lyase (glycerone-phosphate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "rhamnulose-1-phosphate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.19"^^xsd:string) "L-rhamnulose 1-phosphate aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10722715"^^xsd:string) Annotation( "PMID:16854990"^^xsd:string) "Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group."^^xsd:string) AnnotationAssertion(rdfs:label "ribonuclease E activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ribonuclease G activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10722715"^^xsd:string) Annotation( "PMID:16854990"^^xsd:string) "Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at positions 5 and 6 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11948193"^^xsd:string) "Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction, leaving an undigested core of 3-5 nucleotides."^^xsd:string) AnnotationAssertion(rdfs:label "ribonuclease R activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.17.4.2"^^xsd:string) "2'-deoxyribonucleoside-triphosphate:thioredoxin-disulfide 2'-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.4.2"^^xsd:string) "Catalysis of the reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.4.2"^^xsd:string) "ribonucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.4.2"^^xsd:string) "2'-deoxyribonucleoside-triphosphate:oxidized-thioredoxin 2'-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ribonucleoside-triphosphate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ribosomal-protein-alanine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.128"^^xsd:string) "ribosomal protein S18 acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.128"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + ribosomal-protein L-alanine = CoA + ribosomal-protein N-acetyl-L-alanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.128"^^xsd:string) "acetyl-CoA:ribosomal-protein-L-alanine N-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.16"^^xsd:string) "Catalysis of the reaction: L-selenocysteine + reduced acceptor = hydrogen selenide + L-alanine + acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "selenocysteine lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.16"^^xsd:string) "L-selenocysteine selenide-lyase (L-alanine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.16"^^xsd:string) "selenocysteine beta-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.16"^^xsd:string) "selenocysteine reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.30"^^xsd:string) Annotation( "RHEA:24563"^^xsd:string) "Catalysis of the reaction: L-serine + acetyl-CoA = O-acetyl-L-serine + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.30"^^xsd:string) "L-serine acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.30"^^xsd:string) "acetyl-CoA:L-serine O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.30"^^xsd:string) "SATase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.30"^^xsd:string) "serine acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.30"^^xsd:string) "serine transacetylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "serine O-acetyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.4.16.4"^^xsd:string) "D-alanine carboxypeptidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.16.4"^^xsd:string) "D-alanyl-D-alanine-carboxypeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.16.4"^^xsd:string) "DD-peptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.16.4"^^xsd:string) "DD-transpeptidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "serine-type D-Ala-D-Ala carboxypeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.16.4"^^xsd:string) "D-alanyl-D-alanine carboxypeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.16.4"^^xsd:string) "Catalysis of the reaction: (Ac)2-L-Lys-D-alanyl-D-alanine + H2O = (Ac)2-L-Lys-D-alanine + D-alanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.16.4"^^xsd:string) "D-alanyl carboxypeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.16.4"^^xsd:string) "DD-carboxypeptidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.16.4"^^xsd:string) "D-alanyl-D-alanine-cleaving peptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.16.4"^^xsd:string) "D-alanyl-D-alanine-cleaving-peptidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "DNA adenine methylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) Annotation( "EC:2.1.1.72"^^xsd:string) "EcoRI methylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.72"^^xsd:string) "restriction-modification system activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.72"^^xsd:string) "N-6 adenine-specific DNA methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.72"^^xsd:string) "modification methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.72"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine."^^xsd:string) AnnotationAssertion(rdfs:label "site-specific DNA-methyltransferase (adenine-specific) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.-"^^xsd:string) "DNA transmethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.-"^^xsd:string) "deoxyribonucleic acid methyltransferase activity"^^xsd:string) AnnotationAssertion( "DNA methylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.-"^^xsd:string) "deoxyribonucleic acid methylase activity"^^xsd:string) AnnotationAssertion( "DNA methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.-"^^xsd:string) "deoxyribonucleate methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of a methyl group to a DNA molecule."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "Type II DNA methylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.-"^^xsd:string) "deoxyribonucleic acid modification methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.-"^^xsd:string) "deoxyribonucleate methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "site-specific recombinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) "Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.140"^^xsd:string) "Catalysis of the reaction: D-sorbitol 6-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.140"^^xsd:string) "D-sorbitol-6-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.140"^^xsd:string) "D-glucitol-6-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.140"^^xsd:string) "D-sorbitol-6-phosphate:NAD+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.140"^^xsd:string) "glucitol-6-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.140"^^xsd:string) "D-sorbitol 6-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sorbitol-6-phosphate 2-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.140"^^xsd:string) "sorbitol-6-P-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.140"^^xsd:string) "ketosephosphate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.21"^^xsd:string) "ADPglucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.21"^^xsd:string) "ADPG starch synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.21"^^xsd:string) "starch synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.21"^^xsd:string) "ADP-glucose--starch glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.21"^^xsd:string) "Catalysis of the reaction: ADP-glucose + (1,4)-alpha-D-glucosyl(n) = ADP + (1,4)-alpha-D-glucosyl(n+1)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.21"^^xsd:string) "glycogen synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.21"^^xsd:string) "adenosine diphosphate glucose-starch glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.21"^^xsd:string) "ADP-glucose starch synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.21"^^xsd:string) "ADPglucose-starch glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.21"^^xsd:string) "ADP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.21"^^xsd:string) "adenosine diphosphoglucose-starch glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.21"^^xsd:string) "ADPG-starch glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.21"^^xsd:string) "starch (bacterial glycogen) synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "starch synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.21"^^xsd:string) "ADP-glucose transglucosylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "streptomycin 3''-adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.47"^^xsd:string) "AAD (3'')"^^xsd:string) AnnotationAssertion( "ATP:streptomycin 3''-adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.47"^^xsd:string) Annotation( "RHEA:20248"^^xsd:string) "Catalysis of the reaction: ATP + streptomycin = 3''-adenylylstreptomycin + diphosphate + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "aminoglycoside 3''-adenylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.16"^^xsd:string) "succinate semialdehyde dehydrogenase (nicotinamide adenine dinucleotide (phosphate))"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.16"^^xsd:string) "Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.16"^^xsd:string) "succinate-semialdehyde:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "succinate-semialdehyde dehydrogenase [NAD(P)+] activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.18"^^xsd:string) "N-succinyl-L-alpha,epsilon-diaminopimelic acid deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.18"^^xsd:string) Annotation( "RHEA:22611"^^xsd:string) "Catalysis of the reaction: N-succinyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + succinate."^^xsd:string) AnnotationAssertion(rdfs:label "succinyl-diaminopimelate desuccinylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.18"^^xsd:string) "N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.23"^^xsd:string) Annotation( "RHEA:19536"^^xsd:string) "Catalysis of the reaction: N(2)-succinyl-L-arginine + 2 H(2)O + 2 H(+) = N(2)-succinyl-L-ornithine + CO(2) + 2 NH(4)(+)."^^xsd:string) AnnotationAssertion( "N2-succinyl-L-arginine iminohydrolase (decarboxylating)"^^xsd:string) AnnotationAssertion( "succinylarginine dihydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-succinylarginine dihydrolase activity"^^xsd:string) AnnotationAssertion( "arginine succinylhydrolase activity"^^xsd:string) AnnotationAssertion( "AruB"^^xsd:string) AnnotationAssertion( "N2-succinylarginine dihydrolase activity"^^xsd:string) AnnotationAssertion( "AstB"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.23"^^xsd:string) "2-N-succinyl-L-arginine iminohydrolase (decarboxylating)"^^xsd:string) AnnotationAssertion( "SADH"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.17"^^xsd:string) "N-succinyl-L-diaminopimelic glutamic transaminase activity"^^xsd:string) AnnotationAssertion( "succinyldiaminopimelate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "succinyldiaminopimelate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.17"^^xsd:string) Annotation( "RHEA:11963"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + N-succinyl-LL-2,6-diaminopimelate = L-2-succinylamino-6-oxopimelate + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.17"^^xsd:string) "succinyldiaminopimelate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.17"^^xsd:string) "N-succinyl-L-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.96"^^xsd:string) Annotation( "RHEA:15172"^^xsd:string) "Catalysis of the reaction: N-succinyl-L-glutamate + H(2)O = L-glutamate + succinate."^^xsd:string) AnnotationAssertion( "SGDS"^^xsd:string) AnnotationAssertion( "AstE"^^xsd:string) AnnotationAssertion(rdfs:label "succinylglutamate desuccinylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.96"^^xsd:string) "N-succinyl-L-glutamate amidohydrolase activity"^^xsd:string) AnnotationAssertion( "N2-succinylglutamate desuccinylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.7"^^xsd:string) "disaccharide glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.7"^^xsd:string) "sucrose:phosphate alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.7"^^xsd:string) "Catalysis of the reaction: sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.7"^^xsd:string) "sucrose glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sucrose phosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.31"^^xsd:string) "tRNA guanine 1-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.31"^^xsd:string) "transfer ribonucleate guanine 1-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.31"^^xsd:string) "S-adenosyl-L-methionine:tRNA (guanine-1-N-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.31"^^xsd:string) "S-adenosyl-L-methionine:tRNA (guanine-N1-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.31"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methylguanine."^^xsd:string) AnnotationAssertion(rdfs:label "tRNA (guanine-N1-)-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "tRNA guanosine 2'-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "tRNA guanosine-2'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "tRNA (Gm18) 2'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "S-adenosyl-L-methionine:tRNA (guanosine-2'-O-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA (guanosine-2'-O-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylguanosine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "tRNA (guanosine 2')-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "transfer ribonucleate guanosine 2'-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "S-adenosyl-L-methionine:tRNA guanosine-2'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "tRNA (Gm18) methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.56"^^xsd:string) "Catalysis of the reaction: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.56"^^xsd:string) "RNase PH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.56"^^xsd:string) "tRNA:phosphate nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.56"^^xsd:string) "phosphate-dependent exonuclease activity"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.56"^^xsd:string) "ribonuclease PH activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.144"^^xsd:string) "phosphotagatokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.144"^^xsd:string) "Catalysis of the reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "tagatose-6-phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.144"^^xsd:string) "ATP:D-tagatose-6-phosphate 1-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.40"^^xsd:string) "D-tagatose-1,6-bisphosphate aldolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tagatose-bisphosphate aldolase activity"^^xsd:string) AnnotationAssertion( "tagatose-1,6-bisphosphate aldolase 1"^^xsd:string) AnnotationAssertion( "AgaY"^^xsd:string) AnnotationAssertion( "D-tagatose-1,6-bisphosphate triosephosphate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.40"^^xsd:string) "tagatose 1,6-diphosphate aldolase activity"^^xsd:string) AnnotationAssertion( "KbaY"^^xsd:string) AnnotationAssertion( "AgaZ"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.40"^^xsd:string) "D-tagatose-1,6-bisphosphate D-glyceraldehyde 3-phosphate-lyase (glycerone-phosphate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.40"^^xsd:string) Annotation( "RHEA:22951"^^xsd:string) "Catalysis of the reaction: D-tagatose 1,6-diphosphate = D-glyceraldehyde 3-phosphate + glycerone phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.58"^^xsd:string) "altronate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.58"^^xsd:string) "tagaturonate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.58"^^xsd:string) "altronic oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tagaturonate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.58"^^xsd:string) "TagUAR"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.58"^^xsd:string) Annotation( "RHEA:17816"^^xsd:string) "Catalysis of the reaction: D-altronate + NAD(+) = D-tagaturonate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.58"^^xsd:string) "D-tagaturonate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.58"^^xsd:string) "altronate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.58"^^xsd:string) "D-altronate:NAD+ 3-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tartrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.93"^^xsd:string) "tartrate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.93"^^xsd:string) "Catalysis of the reaction: tartrate + NAD+ = oxaloglycolate + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.93"^^xsd:string) "mesotartrate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.47"^^xsd:string) Annotation( "RHEA:10139"^^xsd:string) "Catalysis of the reaction: 2 glyoxylate + H(+) = 2-hydroxy-3-oxopropanoate + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.47"^^xsd:string) "glyoxylic carbo-ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.47"^^xsd:string) "glyoxylate carboligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.47"^^xsd:string) "glyoxalate carboligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.47"^^xsd:string) "glyoxylate carbo-ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.47"^^xsd:string) "glyoxylate carboxy-lyase (dimerizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.47"^^xsd:string) "tartronic semialdehyde carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.47"^^xsd:string) "hydroxymalonic semialdehyde carboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tartronate-semialdehyde synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.47"^^xsd:string) "glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.47"^^xsd:string) "tartronate semialdehyde carboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.130"^^xsd:string) Annotation( "RHEA:20703"^^xsd:string) "Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + ATP = ADP + 2 H(+) + lipid IV(a)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.130"^^xsd:string) "ATP:2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-beta-D-1,6-glucosaminyl-beta-phosphate 4'-O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tetraacyldisaccharide 4'-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.130"^^xsd:string) "lipid-A 4'-kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.4.16"^^xsd:string) "thiamine-monophosphate kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiamine-phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "thiamin phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.16"^^xsd:string) "ATP:thiamine-phosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.16"^^xsd:string) "thiamin-monophosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.16"^^xsd:string) Annotation( "RHEA:15916"^^xsd:string) "Catalysis of the reaction: ATP + thiamine phosphate = ADP + H(+) + thiamine diphosphate."^^xsd:string) AnnotationAssertion( "thiamin-phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.16"^^xsd:string) "thiamin monophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.16"^^xsd:string) "thiamin monophosphokinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.4"^^xsd:string) "deoxythymidine phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.4"^^xsd:string) "thymidine-orthophosphate deoxyribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.4"^^xsd:string) "pyrimidine phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.4"^^xsd:string) "thymidine:phosphate deoxy-alpha-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.4"^^xsd:string) "blood platelet-derived endothelial cell growth factor"^^xsd:string) AnnotationAssertion(rdfs:label "thymidine phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.4"^^xsd:string) "animal growth regulators, blood platelet-derived endothelial cell growth factors"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.4"^^xsd:string) "pyrimidine deoxynucleoside phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.4"^^xsd:string) "gliostatins"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.4"^^xsd:string) "thymidine:phosphate deoxy-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.4"^^xsd:string) "Catalysis of the reaction: thymidine + phosphate = thymine + 2-deoxy-D-ribose 1-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "trimethylamine-N-oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.6.9"^^xsd:string) "Catalysis of the reaction: NADH + H+ + trimethylamine-N-oxide = NAD+ + trimethylamine + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.6.9"^^xsd:string) "trimethylamine oxide reductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.6.9"^^xsd:string) "trimethylamine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.6.9"^^xsd:string) "trimethylamine N-oxide reductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.6.9"^^xsd:string) "NADH:trimethylamine-N-oxide oxidoreductase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.99.1"^^xsd:string) Annotation( "RHEA:19556"^^xsd:string) "Catalysis of the reaction: L-tryptophan + H(2)O = indole + NH(4)(+) + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.1"^^xsd:string) "TNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.1"^^xsd:string) "L-tryptophan indole-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.1"^^xsd:string) "L-tryptophanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.1"^^xsd:string) "tryptophan catabolism, using tryptophanase"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.1"^^xsd:string) "tryptophan catabolic process, using tryptophanase"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.1"^^xsd:string) "L-tryptophan indole-lyase (deaminating; pyruvate forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.1"^^xsd:string) "L-tryptophan indole-lyase (deaminating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "tryptophanase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Type I site-specific deoxyribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.3"^^xsd:string) Annotation( "PMID:15788748"^^xsd:string) "Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions; ATP is simultaneously hydrolyzed. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.3"^^xsd:string) "ATP-dependent DNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.3"^^xsd:string) "deoxyribonuclease (adenosine triphosphate-hydrolyzing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.3"^^xsd:string) "adenosine triphosphate-dependent deoxyribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.3"^^xsd:string) "type I site-specific deoxyribonuclease activity"^^xsd:string) AnnotationAssertion( "Type I restriction enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.3"^^xsd:string) "deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Type II restriction enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.4"^^xsd:string) Annotation( "PMID:12654995"^^xsd:string) "Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site."^^xsd:string) AnnotationAssertion(rdfs:label "Type II site-specific deoxyribonuclease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tyrosine-based site-specific recombinase activity"^^xsd:string) AnnotationAssertion( "tyrosine recombinase"^^xsd:string) AnnotationAssertion( "site-specific tyrosine recombinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:11090626"^^xsd:string) "Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphotyrosyl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a tyrosine in the active site."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.66"^^xsd:string) "C55-isoprenoid alcohol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.66"^^xsd:string) "C55-isoprenoid alcohol phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.66"^^xsd:string) "isoprenoid alcohol phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.66"^^xsd:string) "ATP:undecaprenol phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.66"^^xsd:string) "isoprenoid alcohol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.66"^^xsd:string) "isoprenoid-alcohol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.66"^^xsd:string) "polyisoprenol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.66"^^xsd:string) "C55-isoprenyl alcohol phosphokinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "undecaprenol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.66"^^xsd:string) Annotation( "RHEA:23755"^^xsd:string) "Catalysis of the reaction: ATP + undecaprenol = ADP + undecaprenyl phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.66"^^xsd:string) "isoprenoid alcohol kinase (phosphorylating)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "urease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.5"^^xsd:string) "urea amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.5"^^xsd:string) "Catalysis of the reaction: urea + H2O = CO2 + 2 NH3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ureidoglycolate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.154"^^xsd:string) "(S)-ureidoglycolate:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.154"^^xsd:string) Annotation( "PMID:23284870"^^xsd:string) "Catalysis of the reaction: (S)-ureidoglycolate + NAD(P)+ = oxalureate + NAD(P)H + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Catalysis of the reaction: ATP + (d)UMP = ADP + (d)UDP."^^xsd:string) AnnotationAssertion(rdfs:label "uridylate kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "valine-pyruvate transaminase activity"^^xsd:string) AnnotationAssertion( "valine-pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.66"^^xsd:string) Annotation( "RHEA:22915"^^xsd:string) "Catalysis of the reaction: L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.66"^^xsd:string) "alanine-oxoisovalerate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.66"^^xsd:string) "transaminase C activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.66"^^xsd:string) "valine--pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.66"^^xsd:string) "L-valine:pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.66"^^xsd:string) "alanine--valine transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.37"^^xsd:string) "1,4-beta-D-xylan xylohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.37"^^xsd:string) "xylobiase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.37"^^xsd:string) "beta-D-xylopyranosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.37"^^xsd:string) "exo-1,4-beta-xylosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "xylan 1,4-beta-xylosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.37"^^xsd:string) "exo-1,4-xylosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.37"^^xsd:string) "Catalysis of the hydrolysis of (1->4)-beta-D-xylans so as to remove successive D-xylose residues from the non-reducing termini."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.37"^^xsd:string) "beta-xylosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.37"^^xsd:string) "exo-1,4-beta-D-xylosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "xylose isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.5"^^xsd:string) "D-xylose ketoisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.5"^^xsd:string) "D-xylose isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.5"^^xsd:string) "D-xylose aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.5"^^xsd:string) "D-xylose ketol-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.5"^^xsd:string) "Catalysis of the reaction: D-xylose = D-xylulose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.4.17.14"^^xsd:string) "DD-carboxypeptidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.17.14"^^xsd:string) "DD-carboxypeptidase-transpeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.17.14"^^xsd:string) "G enzyme"^^xsd:string) AnnotationAssertion(rdfs:label "zinc D-Ala-D-Ala carboxypeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.17.14"^^xsd:string) "Zn(2+) G peptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.17.14"^^xsd:string) "D-alanyl-D-alanine-cleaving carboxypeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.17.14"^^xsd:string) "Catalysis of the cleavage of the D-alanyl-D-alanine bond in (Ac)2-L-lysyl-D-alanyl-D-alanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.17.14"^^xsd:string) "Zn2+ G peptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.17.14"^^xsd:string) "D-alanyl-D-alanine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "electron carrier, chlorophyll electron transport system"^^xsd:string) AnnotationAssertion( "iron-sulfur electron transfer carrier"^^xsd:string) AnnotationAssertion(rdfs:label "electron carrier activity"^^xsd:string) AnnotationAssertion( "2Fe-2S electron transfer carrier"^^xsd:string) AnnotationAssertion( "electron transfer flavoprotein"^^xsd:string) AnnotationAssertion( "3Fe-4S/4Fe-4S electron transfer carrier"^^xsd:string) AnnotationAssertion( "adrenodoxin-type ferredoxin"^^xsd:string) AnnotationAssertion( "high-potential iron-sulfur carrier"^^xsd:string) AnnotationAssertion( "redox-active disulfide bond electron carrier"^^xsd:string) AnnotationAssertion( "mononuclear iron electron carrier"^^xsd:string) AnnotationAssertion( "electron donor activity"^^xsd:string) AnnotationAssertion( "chloroplast-type ferredoxin"^^xsd:string) AnnotationAssertion( "electron transfer flavoprotein, group II"^^xsd:string) AnnotationAssertion( "electron transfer flavoprotein, group I"^^xsd:string) AnnotationAssertion( "electron transporter activity"^^xsd:string) AnnotationAssertion( "small blue copper electron carrier"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient."^^xsd:string) AnnotationAssertion( "azurin"^^xsd:string) AnnotationAssertion( "copper electron carrier"^^xsd:string) AnnotationAssertion( "polyferredoxin"^^xsd:string) AnnotationAssertion( "amicyanin"^^xsd:string) AnnotationAssertion( "rubredoxin"^^xsd:string) AnnotationAssertion( "dicluster bacterial-type ferredoxin"^^xsd:string) AnnotationAssertion( "electron acceptor activity"^^xsd:string) AnnotationAssertion( "thioredoxin-like 2Fe-2S ferredoxin"^^xsd:string) AnnotationAssertion( "bacterial-type ferredoxin"^^xsd:string) AnnotationAssertion( "monocluster bacterial-type ferredoxin"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "biotin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions."^^xsd:string) AnnotationAssertion( "vitamin B7 binding"^^xsd:string) AnnotationAssertion( "vitamin H binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:9442895"^^xsd:string) "Catalysis of the unwinding of the DNA helix of DNA containing four-way junctions, including Holliday junctions."^^xsd:string) AnnotationAssertion( "Holliday junction helicase activity"^^xsd:string) AnnotationAssertion(rdfs:label "four-way junction helicase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "excinuclease ABC activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:15192705"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid at sites flanking regions of damaged DNA to which the Uvr ABC excinuclease complexes bind."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "rRNA m5C967 methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "rRNA (cytosine-C5-)-methyltransferase activity"^^xsd:string) AnnotationAssertion( "rRNA (cytosine-C5-967)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "PMID:10026269"^^xsd:string) Annotation( "PMID:18786544"^^xsd:string) "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to cytosine to form 5-methylcytosine in small subunit ribosomal RNA."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.60"^^xsd:string) "acylmannosamine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.60"^^xsd:string) "acylaminodeoxymannokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.60"^^xsd:string) "acetylmannosamine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.60"^^xsd:string) "acylmannosamine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "N-acylmannosamine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.60"^^xsd:string) "ATP:N-acetylmannosamine 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.60"^^xsd:string) "Catalysis of the reaction: ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.60"^^xsd:string) "acetylamidodeoxymannokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.60"^^xsd:string) "N-acyl-D-mannosamine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.60"^^xsd:string) "ATP:N-acyl-D-mannosamine 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.60"^^xsd:string) "N-acetylmannosamine kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "N-acylmannosamine-6-P epimerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acylmannosamine-6-phosphate 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:NANE-RXN"^^xsd:string) "Catalysis of the reaction: N-acetyl-D-mannosamine-6-phosphate = N-acetyl-D-glucosamine-6-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "dimethyl sulphoxide reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dimethyl sulfoxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0207"^^xsd:string) "Catalysis of the reaction: dimethyl sulfoxide + H+ = dimethyl sulfide + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-acetyl-anhydromuramoyl-L-alanine amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-5225"^^xsd:string) "Catalysis of the reaction: GlcNAc-1,6-anhMurNAc-L-Ala-gamma-D-Glu-DAP-D-Ala + H2O glcNAc-1,6-anhMurNAc + L-Ala-gamma-D-Glu-DAP-D-Ala."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "receptor signaling protein serine/threonine phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate."^^xsd:string) AnnotationAssertion( "receptor signalling protein serine/threonine phosphatase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN0-5268"^^xsd:string) "Catalysis of the reaction: 2 ubiquinol + O2 + 4 H+ = 2 ubiquinone + 2 H2O + 4 H+ [periplasmic space]."^^xsd:string) AnnotationAssertion(rdfs:label "cytochrome bo3 ubiquinol oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.10.9.1"^^xsd:string) "plastoquinol-plastocyanin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.9.1"^^xsd:string) "cytochrome b6-f complex activity"^^xsd:string) AnnotationAssertion(rdfs:label "plastoquinol--plastocyanin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.99.1"^^xsd:string) "cytochrome b6f"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.9.1"^^xsd:string) "cytochrome b6/f complex activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.9.1"^^xsd:string) "Catalysis of the reaction: 2 H(+)[side 1] + 2 oxidized plastocyanin + plastoquinol-1 = 2 H(+)[side 2] + 2 reduced plastocyanin + plastoquinone. This reaction involves the concomitant transfer of 2 H+ ions across a membrane."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.9.1"^^xsd:string) "cytochrome b6f complex activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.99.1"^^xsd:string) "plastoquinol/plastocyanin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.99.1"^^xsd:string) "plastoquinol:oxidized-plastocyanin oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "zeaxanthin epoxidase [overall] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.90"^^xsd:string) "zea-epoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.90"^^xsd:string) "zeaxanthin,NAD(P)H:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.90"^^xsd:string) "Catalysis of the reactions: zeaxanthin + NAD(P)H + H+ + O2 = antheraxanthin + NAD(P)+ + H2O; and antheraxanthin + NAD(P)H + H+ + O2 = violaxanthin + NAD(P)+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jy"^^xsd:string) Annotation( "TC:2.A.2.-.-"^^xsd:string) Annotation( "TC:2.A.2.4.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + monovalent cation(out) = sucrose(in) + monovalent cation(in)."^^xsd:string) AnnotationAssertion( "sucrose permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "sucrose:monovalent cation symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "triose-phosphate:phosphate antiporter activity"^^xsd:string) AnnotationAssertion( "triose phosphate antiporter"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:2.A.7.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: triose-phosphate(out) + phosphate(in) = triose-phosphate(in) + phosphate(out)."^^xsd:string) AnnotationAssertion( "triose phosphate translocator"^^xsd:string) AnnotationAssertion( "TPT"^^xsd:string) AnnotationAssertion( "dihydroxyacetone phosphate:phosphate antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:10066586"^^xsd:string) Annotation( "PMID:1990981"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nitrate(out) + H+(out) = nitrate(in) + H+(in)."^^xsd:string) AnnotationAssertion( "nitrate(chlorate):hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "nitrate(chlorate):proton symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "nitrate:hydrogen symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "auxin:proton symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "auxin:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8688077"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: auxin(out) + H+(out) = auxin(in) + H+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "low affinity phosphate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.20.-.-"^^xsd:string) "Catalysis of the transfer of phosphate from one side of the membrane to the other. In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "high affinity potassium transporter"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.38.3.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Na+(out) = K+(in) + Na+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "potassium:sodium symporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "high affinity sulfate:proton symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "high affinity sulfate:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "high affinity sulphate:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "low affinity sulfate:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:7568135"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations."^^xsd:string) AnnotationAssertion( "low affinity sulphate:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "low affinity sulfate:proton symporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:3.A.10.-.-"^^xsd:string) "Catalysis of the hydrolysis of pyrophosphate, which generates a proton motive force."^^xsd:string) AnnotationAssertion( "proton-translocating pyrophosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydrogen-translocating pyrophosphatase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.1.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) + H+(out) = hexose(in) + H+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "hexose:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "hexose:proton symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-arabinokinase activity"^^xsd:string) AnnotationAssertion( "ATP:L-arabinose 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.46"^^xsd:string) "L-arabinokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.46"^^xsd:string) Annotation( "RHEA:20156"^^xsd:string) "Catalysis of the reaction: L-arabinose + ATP = beta-L-arabinose 1-phosphate + ADP + 2 H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.1.1"^^xsd:string) "NADH-dependent nitrate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.1"^^xsd:string) "Catalysis of the reaction: nitrite + NAD+ + H2O = nitrate + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.1"^^xsd:string) "assimilatory nitrate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.1"^^xsd:string) "NADH-nitrate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.1"^^xsd:string) "assimilatory NADH: nitrate reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nitrate reductase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.1"^^xsd:string) "nitrite:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.1"^^xsd:string) "nitrate reductase (NADH(2)) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.1"^^xsd:string) "assimilatory NADH:nitrate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.1"^^xsd:string) "NADH:nitrate oxidoreductase activity"^^xsd:string) AnnotationAssertion( "NADH:nitrate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.1"^^xsd:string) "nitrate reductase (NADH2)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:lr"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "transmembrane receptor histidine kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ethylene-forming enzyme"^^xsd:string) AnnotationAssertion( "ethene-forming enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.4"^^xsd:string) Annotation( "RHEA:23643"^^xsd:string) "Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + L-ascorbate + O(2) = CO(2) + dehydroascorbate + ethylene + 2 H(2)O + hydrogen cyanide. Ethene is also known as ethylene."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.4"^^xsd:string) "aminocyclopropanecarboxylate oxidase activity"^^xsd:string) AnnotationAssertion( "ACC oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-aminocyclopropane-1-carboxylate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.17.4"^^xsd:string) "1-aminocyclopropane-1-carboxylate oxygenase (ethylene-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "AMP dimethylallyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.27"^^xsd:string) Annotation( "RHEA:15288"^^xsd:string) "Catalysis of the reaction: AMP + dimethylallyl diphosphate = N(6)-(dimethylallyl)adenosine 5'-phosphate + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R04038"^^xsd:string) "2-isopentenyl-diphosphate:AMP delta2-isopentenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.27"^^xsd:string) "dimethylallyl-diphosphate:AMP dimethylallyltransferase activity"^^xsd:string) AnnotationAssertion( "2-isopentenyl-diphosphate:AMP 2-isopentenyltransferase activity"^^xsd:string) AnnotationAssertion( "cytokinin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.27"^^xsd:string) "adenylate dimethylallyltransferase activity"^^xsd:string) AnnotationAssertion( "adenylate isopentenyltransferase activity"^^xsd:string) AnnotationAssertion( "isopentenyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:go_curators"^^xsd:string) "The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation."^^xsd:string) AnnotationAssertion( "violet-sensitive opsin"^^xsd:string) AnnotationAssertion( "UV-sensitive opsin"^^xsd:string) AnnotationAssertion(rdfs:label "photoreceptor activity"^^xsd:string) AnnotationAssertion( "short-wave-sensitive opsin"^^xsd:string) AnnotationAssertion( "green-sensitive opsin"^^xsd:string) AnnotationAssertion( "red-sensitive opsin"^^xsd:string) AnnotationAssertion( "blue-sensitive opsin"^^xsd:string) AnnotationAssertion( "long-wave-sensitive opsin"^^xsd:string) AnnotationAssertion( "opsin"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "blue light photoreceptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 400-470nm. The response may involve a change in conformation."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "red or far-red light photoreceptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:lr"^^xsd:string) "The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660-730nm. The response may involve a change in conformation."^^xsd:string) AnnotationAssertion( "red/far-red light photoreceptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:lr"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "cytokinin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:lr"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "transmembrane histidine kinase cytokinin receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ent-kaurene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.19"^^xsd:string) "ent-kaurene synthase B activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.19"^^xsd:string) Annotation( "RHEA:22223"^^xsd:string) "Catalysis of the reaction: ent-copalyl diphosphate = ent-kaur-16-ene + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.19"^^xsd:string) "ent-copalyl-diphosphate diphosphate-lyase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.19"^^xsd:string) "ent-copalyl-diphosphate diphosphate-lyase (cyclizing, ent-kaurene-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.19"^^xsd:string) "ent-kaurene synthetase B activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.5.1.13"^^xsd:string) "ent-kaurene synthetase A activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.13"^^xsd:string) "ent-kaurene synthase A activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.13"^^xsd:string) Annotation( "RHEA:14844"^^xsd:string) "Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = ent-copalyl diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.13"^^xsd:string) "ent-copalyl-diphosphate lyase (decyclizing)"^^xsd:string) AnnotationAssertion(rdfs:label "ent-copalyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion( "diterpene cyclase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alternative oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0943088399"^^xsd:string) "Catalysis of the oxidation of ubiquinol by diverting electrons from the standard electron transfer chain, transferring them from ubiquinol to oxygen and generating water as the product."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0943088399"^^xsd:string) "Catalysis of the removal of a C-5 double bond in the B ring of a sterol."^^xsd:string) AnnotationAssertion(rdfs:label "sterol 5-alpha reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0943088399"^^xsd:string) "Catalysis of the reaction: 5-dehydroepisterol = 24-methylenecholesterol."^^xsd:string) AnnotationAssertion(rdfs:label "sterol delta7 reductase activity"^^xsd:string) AnnotationAssertion( "sterol delta-7 reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Catalysis of the reaction: fatty acid (C-16 or longer) + 2-C = fatty acid (C-16 or longer + 2-C)."^^xsd:string) AnnotationAssertion(rdfs:label "fatty acid elongase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "octadecanal alkane-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "octadecanal decarbonylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.5"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Catalysis of the reaction: octadecanal = heptadecane + CO."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11842140"^^xsd:string) "Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator."^^xsd:string) AnnotationAssertion(rdfs:label "histidine phosphotransfer kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "calcium-dependent protein serine/threonine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions are dependent on the presence of calcium ions."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sm"^^xsd:string) Annotation( "PMID:10871276"^^xsd:string) "Interacting selectively and non-covalently with an amino terminal propeptide, which functions as a sorting signal to sort away the soluble vacuolar protein from Golgi to lytic vacuole via clathrin-coated vesicles."^^xsd:string) AnnotationAssertion(rdfs:label "amino-terminal vacuolar sorting propeptide binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.99.2"^^xsd:string) "APS reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.2"^^xsd:string) "adenosine 5'-phosphosulfate reductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.2"^^xsd:string) "AMP, sulfite:acceptor oxidoreductase (adenosine-5'-phosphosulfate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.2"^^xsd:string) "adenylyl-sulphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.2"^^xsd:string) "adenosine phosphosulfate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.2"^^xsd:string) "AMP, sulfite:(acceptor) oxidoreductase (adenosine-5'-phosphosulfate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.2"^^xsd:string) Annotation( "PMID:5421934"^^xsd:string) "Catalysis of the reaction: AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "adenylyl-sulfate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.2"^^xsd:string) "APS-reductase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "zeinoxanthin epsilon hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-5962"^^xsd:string) Annotation( "PMID:8837513"^^xsd:string) "Catalysis of the reaction: zeinoxanthin + NADPH + O2 + H+ = lutein + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of a ring closure reaction."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12213958"^^xsd:string) "Catalysis of the reaction: alkene group + alcohol group on same molecule = cyclic ether. Substrates are 2-methyl-6-phytyl-1,4- hydroquinone (forms delta-tocopherol) and 2,3-dimethyl-5-phytyl-1,4-hydroquinone (forms gamma-tocopherol)."^^xsd:string) AnnotationAssertion(rdfs:label "tocopherol cyclase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "pH-dependent protein transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11526245"^^xsd:string) "Catalysis of the transfer of proteins from one side of the membrane to the other. Transportation is dependent on pH gradient across the membrane."^^xsd:string) AnnotationAssertion( "delta-pH-dependent protein transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "proton motive force dependent protein transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.92"^^xsd:string) Annotation( "MetaCyc:RXN1F-19"^^xsd:string) Annotation( "PMID:9778849"^^xsd:string) "Catalysis of the reaction: 13(S)-hydroperoxylinolenate = 12,13(S)-epoxylinolenate + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.92"^^xsd:string) "linoleate hydroperoxide isomerase"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.92"^^xsd:string) "linoleic acid hydroperoxide isomerase"^^xsd:string) AnnotationAssertion(rdfs:label "allene oxide synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.92"^^xsd:string) "HPI"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.92"^^xsd:string) "(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase [(9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate-forming]"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "16:0 monogalactosyldiacylglycerol desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "MetaCyc:RXN-1728"^^xsd:string) Annotation( "MetaCyc:RXN-8304"^^xsd:string) Annotation( "MetaCyc:RXN-8307"^^xsd:string) "Catalysis of the introduction of an omega-3 double bond into an unsaturated 16-carbon fatty acid in a monogalactosyldiacylglycerol molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.99.12"^^xsd:string) "tRNA pseudouridylate synthase I activity"^^xsd:string) AnnotationAssertion( "tRNA-pseudouridine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.12"^^xsd:string) "tRNA-uridine uracilmutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.12"^^xsd:string) "tRNA-uridine isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.12"^^xsd:string) "transfer RNA pseudouridine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.12"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.12"^^xsd:string) "transfer ribonucleate pseudouridine synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pseudouridine synthase activity"^^xsd:string) AnnotationAssertion( "tRNA-pseudouridine synthase I activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "auxin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sm"^^xsd:string) "Interacting selectively and non-covalently with auxin, plant hormones that regulate aspects of plant growth."^^xsd:string) AnnotationAssertion( "auxin receptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "steroid 22-alpha hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Catalysis of the reaction: 5-alpha-campestanaol + O2 = 6-deoxocathasterone + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sm"^^xsd:string) "Interacting selectively and non-covalently with N-1-naphthylphthalamic acid, an auxin transport inhibitor."^^xsd:string) AnnotationAssertion(rdfs:label "N-1-naphthylphthalamic acid binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Catalysis of the transfer of a nucleoside, from one side of a membrane to the other, up a concentration gradient."^^xsd:string) AnnotationAssertion(rdfs:label "nucleoside transmembrane transporter activity, against a concentration gradient"^^xsd:string) AnnotationAssertion( "concentrative nucleoside transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sphingosine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Catalysis of the transfer of amino alcohol sphingosine from one side of the membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-2541"^^xsd:string) Annotation( "PMID:14512521"^^xsd:string) "Catalysis of the reaction: homogentisate + phytyl diphosphate + H+ = 2-methyl-6-phytyl-1,4-benzoquinone + CO2 + diphosphate. 2-methyl-6-phytyl-1,4-benzoquinone is also known as 2-methyl-6-phytylplastoquinol."^^xsd:string) AnnotationAssertion(rdfs:label "homogentisate phytyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-2202"^^xsd:string) "methylthioalkylmalate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-(2'-methylthio)ethylmalate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-2202"^^xsd:string) "Catalysis of the reaction: 2-oxo-4-methylthiobutanoate + acetyl-CoA + H2O = 2-(2'-methylthio)ethylmalic-acid + coenzyme A + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "IAA-amino acid conjugate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Catalysis of the cleavage of the amide bond between IAA (auxin) and the conjugated amino acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-2981"^^xsd:string) "Catalysis of the reaction: indole-3-acetyl-alanine + H2O = indole-3-acetate + L-alanine."^^xsd:string) AnnotationAssertion(rdfs:label "IAA-Ala conjugate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "myrosinase binding"^^xsd:string) AnnotationAssertion(rdfs:label "thioglucosidase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Interacting selectively and non-covalently with the enzyme thioglucosidase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "flavin mononucleotide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Interacting selectively and non-covalently with FMN, flavin mononucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes."^^xsd:string) AnnotationAssertion(rdfs:label "FMN binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a vacuolar sorting signal, a specific peptide sequence that acts as a signal to localize the protein within the vacuole."^^xsd:string) AnnotationAssertion(rdfs:label "vacuolar sorting signal binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "IAA-Phe conjugate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:syr"^^xsd:string) "Catalysis of the reaction: indole-3-acetyl-phenylalanine + H2O = indole-3-acetate + phenylalanine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "IAA-Leu conjugate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-2982"^^xsd:string) "Catalysis of the reaction: indole-3-acetyl-leucine + H2O = indole-3-acetate + L-leucine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kd"^^xsd:string) Annotation( "GOC:syr"^^xsd:string) Annotation( "PMID:17091926"^^xsd:string) Annotation( "PMID:7948862"^^xsd:string) "Catalysis of the reaction: 2 H2O = O2 + 4 H+ + 4 e-. The evolution of oxygen from oxidizing water is carried out by the oxygen evolving complex in photosystem II of plants. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle."^^xsd:string) AnnotationAssertion(rdfs:label "oxygen evolving activity"^^xsd:string) AnnotationAssertion( "photosynthetic water oxidation"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phytol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-7683"^^xsd:string) "Catalysis of the reaction: phytol + CTP = phytyl monophosphate + CDP + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "chlorophyll a oxygenation activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.14"^^xsd:string) "chlorophyll-b synthesis activity"^^xsd:string) AnnotationAssertion(rdfs:label "chlorophyllide a oxygenase [overall] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.14"^^xsd:string) Annotation( "MetaCyc:RXN-7677"^^xsd:string) "Catalysis of the reactions: chlorophyllide a + O2 + NADPH + H+ = 7-hydroxychlorophyllide a + H2O + NADP+; and 7-hydroxychlorophyllide a + O2 + NADPH + H+ = chlorophyllide b + 2 H2O + NADP+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.14"^^xsd:string) "chlorophyllide-a oxygenation activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.14"^^xsd:string) "CAO activity"^^xsd:string) AnnotationAssertion( "chlorophyll b synthesis activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.14"^^xsd:string) "chlorophyllide a:oxygen 7-oxidoreduction activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) "IAA amino acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) "IAA amino acid conjugate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15659623"^^xsd:string) "Catalysis of the reaction: indole-3-acetic acid + an amino acid = an indole-3-acetic acid amide conjugate."^^xsd:string) AnnotationAssertion( "IAA amido synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "indole-3-acetic acid amido synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-L-rhamnose synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase-4-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-5482"^^xsd:string) Annotation( "PMID:14701918"^^xsd:string) "Catalysis of the reaction: UDP-D-glucose + NADPH + H+ = UDP-L-rhamnose + NADP+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10066819"^^xsd:string) Annotation( "PMID:7592828"^^xsd:string) "Catalysis of the reaction: pinoresinol + NADPH + H+ = lariciresinol + NADP+."^^xsd:string) AnnotationAssertion(rdfs:label "pinoresinol reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10066819"^^xsd:string) Annotation( "PMID:7592828"^^xsd:string) "Catalysis of the reaction: lariciresinol + NADPH + H+ = secoisolariciresinol + NADP+."^^xsd:string) AnnotationAssertion(rdfs:label "lariciresinol reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.83"^^xsd:string) "LL-DAP-AT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.83"^^xsd:string) "LL-diaminopimelate transaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L,L-diaminopimelate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.83"^^xsd:string) "LL-DAP aminotransferase activity"^^xsd:string) AnnotationAssertion( "LL-diaminopimelate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.83"^^xsd:string) Annotation( "RHEA:23991"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + LL-2,6-diaminopimelate = (S)-2,3,4,5-tetrahydrodipicolinate + L-glutamate + H(2)O + H(+)."^^xsd:string) AnnotationAssertion( "LL-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:9681016"^^xsd:string) "Enables the directed movement of chlorophyll catabolites such as non-fluorescent chlorophyll catabolites (NCCs), from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "chlorophyll catabolite transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "beta-carotene hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:MONOMER-12386"^^xsd:string) Annotation( "PMID:16492736"^^xsd:string) "Catalysis of the reaction: a carotene + a reduced electron acceptor + O2 = C3-hydroxylated carotene + an oxidized electron acceptor + H2O. This is a general reaction to represent the C3 hydroxylation of the beta ring of a carotene."^^xsd:string) AnnotationAssertion(rdfs:label "carotene beta-ring hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GTP:GDP antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10514379"^^xsd:string) Annotation( "PMID:12553910"^^xsd:string) Annotation( "PMID:16553903"^^xsd:string) "Catalysis of the reaction: GTP(out) + GDP(in) = GTP(in) + GDP(out)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.3.14"^^xsd:string) "abscisic-aldehyde:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "abscisic aldehyde oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.14"^^xsd:string) "AOdelta"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.14"^^xsd:string) "AAO3"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.14"^^xsd:string) "abscisic-aldehyde oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.14"^^xsd:string) Annotation( "RHEA:20532"^^xsd:string) "Catalysis of the reaction: (+)-abscisic aldehyde + H(2)O + O(2) = abscisate + H(2)O(2) + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "DOI:10.1016/j.tetasy.2004.11.062"^^xsd:string) "Catalysis of the reaction: (+)-abscisate + UDP-D-glucose = abscisic acid glucose ester + UDP."^^xsd:string) AnnotationAssertion(rdfs:label "abscisic acid glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.93"^^xsd:string) "abscisate,NADPH:oxygen oxidoreductase (8'-hydroxylating)"^^xsd:string) AnnotationAssertion( "abscisic acid 8'-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.93"^^xsd:string) Annotation( "RHEA:12900"^^xsd:string) "Catalysis of the reaction: (+)-abscisate + H(+) + NADPH + O(2) = (+)-8'-hydroxyabscisate + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.93"^^xsd:string) "ABA 8'-hydroxylase activity"^^xsd:string) AnnotationAssertion( "ABA 8'-Hydroxylase activity, Abscisate 8'-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(+)-abscisic acid 8'-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.93"^^xsd:string) "(+)-ABA 8'-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-8409"^^xsd:string) Annotation( "PMID:16870359"^^xsd:string) "Catalysis of the reaction: protein C-terminal S-farnesyl-L-cysteine methyl ester + H2O = protein C-terminal S-farnesyl-L-cysteine + methanol + H+."^^xsd:string) AnnotationAssertion(rdfs:label "prenylcysteine methylesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "heteropolysaccharide binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16640603"^^xsd:string) "Interacting selectively and non-covalently with heteropolysaccharides. A heteropolysaccharide is a glycan composed of more than one type of monosaccharide residue."^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "heteroglycan binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-8275"^^xsd:string) Annotation( "PMID:16766671"^^xsd:string) "Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+."^^xsd:string) AnnotationAssertion(rdfs:label "dihydrocamalexic acid decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "xanthoxin dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.288"^^xsd:string) "ABA2"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.288"^^xsd:string) "xanthoxin:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.288"^^xsd:string) Annotation( "RHEA:12551"^^xsd:string) "Catalysis of the reaction: NAD(+) + xanthoxin = (+)-abscisic aldehyde + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.288"^^xsd:string) "xanthoxin oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.142"^^xsd:string) "dextrin alpha-1,6-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "limit dextrinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.142"^^xsd:string) "Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in alpha- and beta-limit dextrins of amylopectin and glycogen, and in amylopectin and pullulan."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.142"^^xsd:string) "R-enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.142"^^xsd:string) "amylopectin-1,6-glucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16377628"^^xsd:string) "Modulates the enzyme activity of acetylglutamate kinase."^^xsd:string) AnnotationAssertion(rdfs:label "acetylglutamate kinase regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.53"^^xsd:string) Annotation( "RHEA:14164"^^xsd:string) "Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 3-(methylthio)propanoate + CO + formate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.53"^^xsd:string) "E-2 activity"^^xsd:string) AnnotationAssertion(rdfs:label "acireductone dioxygenase (Ni2+-requiring) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.53"^^xsd:string) "ARD activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.53"^^xsd:string) "acireductone dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.53"^^xsd:string) "2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.53"^^xsd:string) "1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate- and CO-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.54"^^xsd:string) "acireductone dioxygenase activity"^^xsd:string) AnnotationAssertion( "ARD'"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.54"^^xsd:string) "1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate-forming)"^^xsd:string) AnnotationAssertion( "E-2'"^^xsd:string) AnnotationAssertion( "ARD1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.54"^^xsd:string) Annotation( "RHEA:24507"^^xsd:string) "Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 4-methylthio-2-oxobutanoate + formate + H(+)."^^xsd:string) AnnotationAssertion( "acireductone dioxygenase (Fe2+-requiring) activity"^^xsd:string) AnnotationAssertion(rdfs:label "acireductone dioxygenase [iron(II)-requiring] activity"^^xsd:string) AnnotationAssertion( "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase activity"^^xsd:string) AnnotationAssertion( "2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase"^^xsd:string) AnnotationAssertion( "aci-reductone dioxygenase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:15486102"^^xsd:string) "Interacting selectively and non-covalently with phytochrome."^^xsd:string) AnnotationAssertion(rdfs:label "phytochrome binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:tair_curators"^^xsd:string) "Interacting selectively and non-covalently with phosphatidylinositol-5-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 5' position."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol-5-phosphate binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methionine-oxo-acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-2201"^^xsd:string) Annotation( "PMID:17056707"^^xsd:string) "Catalysis of the reaction: methionine + a 2-oxo acid = 2-oxo-4-methylthiobutanoate + an amino acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:17163883"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + (Z)-3-hexen-1-ol = CoA + (Z)-3-hexen-1-yl acetate."^^xsd:string) AnnotationAssertion( "hexenol acetyltransferase"^^xsd:string) AnnotationAssertion(rdfs:label "acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "auxin influx facilitator"^^xsd:string) AnnotationAssertion(rdfs:label "auxin influx transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16839804"^^xsd:string) "Catalysis of the transfer of auxin, from one side of a membrane to the other, into a cell."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16839804"^^xsd:string) "Catalysis of the transfer of auxin, from one side of a membrane to the other, out of a cell."^^xsd:string) AnnotationAssertion(rdfs:label "auxin efflux transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "auxin efflux facilitator"^^xsd:string) AnnotationAssertion( "auxin efflux carrier"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "gibberellin receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tair_curators"^^xsd:string) "Interacting selectively and non-covalently with gibberellins, plant hormones that regulate aspects of plant growth."^^xsd:string) AnnotationAssertion(rdfs:label "gibberellin binding"^^xsd:string) AnnotationAssertion( "gibberellic acid receptor"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "terpene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.-"^^xsd:string) Annotation( "GOC:tair_curators"^^xsd:string) "Catalysis of the formation of cyclic terpenes through the cyclization of linear terpenes (e.g. isopentenyl-PP, geranyl-PP, farnesyl-PP and geranylgeranyl-PP) containing varying numbers of isoprene units."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.-"^^xsd:string) Annotation( "GOC:tair_curators"^^xsd:string) "Catalysis of the reaction: trans,trans-farnesyl diphosphate = a sesquiterpene + diphosphate. Sesquiterpenes are terpenes containing three isoprene units, i.e. 15 carbons."^^xsd:string) AnnotationAssertion(rdfs:label "sesquiterpene synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:17220201"^^xsd:string) "Catalysis of the transfer of a methyl group to the carboxyl group of an acceptor molecule to form a methyl ester."^^xsd:string) AnnotationAssertion(rdfs:label "carboxyl-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:17220201"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + a gibberellin = S-adenosyl-L-homocysteine + a gibberellin methyl ester."^^xsd:string) AnnotationAssertion(rdfs:label "gibberellin carboxyl-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:15550539"^^xsd:string) Annotation( "PMID:16595667"^^xsd:string) "Catalysis of the reaction: L-galactose-1-phosphate + H2O = L-galactose + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "L-galactose-1-phosphate phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "lithium:proton antiporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "lithium:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17270011"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Li+(in) + H+(out) = Li+(out) + H+(in)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-galactose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12047629"^^xsd:string) "Catalysis of the reaction: L-galactose + NAD+ = L-galactono-1,4-lactone + NADH + H+."^^xsd:string) AnnotationAssertion( "L-galactose 1-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "homogentisate prenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16989822"^^xsd:string) "Catalysis of the transfer of a prenyl group from one compound (donor) to homogentisic acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16989822"^^xsd:string) "Catalysis of the reaction: homogentisic acid + farnesyl diphosphate = 2-methyl-6-farnesylplastoquinol."^^xsd:string) AnnotationAssertion(rdfs:label "homogentisate farnesyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16989822"^^xsd:string) "Catalysis of the reaction: homogentisic acid + geranylgeranyl diphosphate = 2-methyl-6-geranylgeranylplastoquinol."^^xsd:string) AnnotationAssertion(rdfs:label "homogentisate geranylgeranyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "homogentisate solanesyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16989822"^^xsd:string) "Catalysis of the reaction: homogentisic acid + all-trans-nonaprenyl diphosphate + 3 H+ = 2-methyl-6-solanyl-1,4-benzoquinonone + CO2 + diphosphate. 2-methyl-6-solanyl-1,4-benzoquinonone is also known as 2-methyl-6-solanesylplastoquinol and all-trans-nonaprenyl diphosphate as solanesyl diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "double-stranded methylated DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17242155"^^xsd:string) "Interacting selectively and non-covalently with double-stranded methylated DNA. Cytosine methylation in DNA is an important mechanism for establishing stable heritable epigenetic marks."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:9628017"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + 3-polyprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-polyprenyl-4-hydroxy-5-methoxybenzoate + H+."^^xsd:string) AnnotationAssertion(rdfs:label "polyprenyldihydroxybenzoate methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ABA binding"^^xsd:string) AnnotationAssertion( "abscisate binding"^^xsd:string) AnnotationAssertion(rdfs:label "abscisic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17347412"^^xsd:string) "Interacting selectively and non-covalently with abscisic acid, plant hormones that regulate aspects of plant growth."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methyl-CpNpG binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17239600"^^xsd:string) "Interacting selectively and non-covalently with a methylated cytosine/unspecified/guanine trinucleotide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methyl-CpNpN binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17239600"^^xsd:string) "Interacting selectively and non-covalently with a methylated cytosine/unspecified/unspecified trinucleotide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16963437"^^xsd:string) "Catalysis of the reaction: ATP + 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid + coenzyme A = AMP + diphosphate + 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoyl-CoA + H+. 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid is also known as OPC-8:0."^^xsd:string) AnnotationAssertion( "3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid (OPC-8:0) CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10695"^^xsd:string) "3-oxo-2-(2'-[Z]-pentenyl)cyclopentane-1-octanoate CoA ligase activity"^^xsd:string) AnnotationAssertion( "OPC-8:0 CoA ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "carotenoid-cleaving dioxygenase"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16459333"^^xsd:string) "Catalysis of the oxidative cleavage of carotenoids."^^xsd:string) AnnotationAssertion(rdfs:label "carotenoid dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16459333"^^xsd:string) "Catalysis of the oxidative cleavage of carotenoids at the (9, 10) and/or (9', 10') double bond."^^xsd:string) AnnotationAssertion(rdfs:label "9,10 (9', 10')-carotenoid-cleaving dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Catalysis of the transmembrane transfer of an ion by a channel that opens in response to a light stimulus."^^xsd:string) AnnotationAssertion(rdfs:label "light-activated ion channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Combining with nerve growth factor (NGF), to prevent apoptosis in neurons and promote nerve growth, or to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "nerve growth factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PR:000011194"^^xsd:string) "NGF receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PR:000011194"^^xsd:string) "beta-nerve growth factor receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN4FS-12"^^xsd:string) "GDP-L-galactose:mannose-1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:AT4G26850-MONOMER"^^xsd:string) "GDP-L-galactose phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN4FS-12"^^xsd:string) Annotation( "PMID:17485667"^^xsd:string) "Catalysis of the reaction: GDP-L-galactose + alpha-D-mannose 1-phosphate = GDP-alpha-D-mannose + alpha-L-galactose-1-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "GDP-galactose:mannose-1-phosphate guanylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN4FS-13"^^xsd:string) Annotation( "PMID:17485667"^^xsd:string) "Catalysis of the reaction: GDP-L-galactose + alpha-D-glucose 1-phosphate = alpha-L-galactose-1-phosphate + GDP-alpha-D-glucose."^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:AT4G26850-MONOMER"^^xsd:string) "GDP-L-galactose phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN4FS-13"^^xsd:string) "GDP-L-galactose:glucose-1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "GDP-galactose:glucose-1-phosphate guanylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:17485667"^^xsd:string) "Catalysis of the reaction: GDP-L-galactose + myo-inositol 1-phosphate = alpha-L-galactose-1-phosphate + GDP-myoinositol."^^xsd:string) AnnotationAssertion(rdfs:label "GDP-galactose:myoinositol-1-phosphate guanylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "GDP:glucose-1-phosphate guanyltransferase activity "^^xsd:string) AnnotationAssertion(rdfs:label "glucose-1-phosphate guanylyltransferase (GDP) activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17462988"^^xsd:string) "Catalysis of the reaction: GDP + D-glucose 1-phosphate = phosphate + GDP-glucose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "galactose-1-phosphate guanylyltransferase (GDP) activity"^^xsd:string) AnnotationAssertion( "GDP:galactose-1-phosphate guanyltransferase activity "^^xsd:string) AnnotationAssertion(Annotation( "PMID:17462988"^^xsd:string) "Catalysis of the reaction: GDP + L-galactose 1-phosphate = phosphate + GDP-galactose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "H3 histone acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H3 = CoA + acetyl-histone H3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "H4 histone acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "manganese:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "manganese:proton antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17559518"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Mn2+(in) + H+(out) = Mn2+(out) + H+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.79"^^xsd:string) Annotation( "MetaCyc:RXN-11190"^^xsd:string) Annotation( "PMID:17560575"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+."^^xsd:string) AnnotationAssertion(rdfs:label "thermospermine synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:17630273"^^xsd:string) "Catalysis of the reaction: UDP-galactose + N-glycan = galactose-beta-1,3-N-glycan + UDP."^^xsd:string) AnnotationAssertion(rdfs:label "UDP-galactose:N-glycan beta-1,3-galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-4-keto-6-deoxy-glucose-3,5-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tair_curators"^^xsd:string) Annotation( "PMID:17190829"^^xsd:string) "Catalysis of the reaction: UDP-4-keto-6-deoxyglucose = UDP-4-keto-rhamnose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-4-keto-rhamnose-4-keto-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tair_curators"^^xsd:string) Annotation( "PMID:17190829"^^xsd:string) "Catalysis of the reaction: UDP-4-keto-rhamnose + NADPH = UDP-rhamnose + NADP+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UTP:arabinose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17341835"^^xsd:string) "Catalysis of the reaction: alpha-L-arabinose 1-phosphate + UTP = UDP-L-arabinose + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "telomerase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:krc"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Stops, prevents or reduces the activity of a telomerase. Telomerase catalyzes the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of nitrate from the inside of the cell to the outside of the cell across a membrane."^^xsd:string) AnnotationAssertion(rdfs:label "nitrate efflux transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Modulates the activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal."^^xsd:string) AnnotationAssertion(rdfs:label "metalloenzyme regulator activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Increases the activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal."^^xsd:string) AnnotationAssertion(rdfs:label "metalloenzyme activator activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:jp"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) Annotation( "PMID:18690240"^^xsd:string) "Increases the activity of an aceyltransferase, an enzyme which catalyzes the transfer of an acetyl group to an acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "acetyltransferase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:jp"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "acetyltransferase stimulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "serum response element binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Interacting selectively and non-covalently with the serum response element (SRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "recombination hotspot binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Interacting selectively and non-covalently with a region in a genome which promotes recombination."^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "DNA binding, recombination hotspot"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Modulates the activity of an enzyme that catalyzes a ring closure reaction."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Decreases the activity of an enzyme that catalyzes a ring closure reaction."^^xsd:string) AnnotationAssertion(rdfs:label "cyclase inhibitor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Increases the activity of an enzyme that catalyzes a ring closure reaction."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "adenylate cyclase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Modulates the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "adenylate cyclase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Decreases the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "adenylate cyclase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Increases the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcium-dependent protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP. This reaction requires the presence of calcium."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcium-dependent protein kinase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Modulates the activity of a calcium-dependent protein kinase, an enzyme which phosphorylates a protein in a calcium-dependent manner."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Stops, prevents or reduces the activity of a calcium-dependent cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile in a calcium-dependent manner."^^xsd:string) AnnotationAssertion(rdfs:label "calcium-dependent cysteine-type endopeptidase inhibitor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thyroid hormone receptor activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) Annotation( "PMID:9346901"^^xsd:string) "A receptor activator activity that binds to, thyroid hormone receptor in a ligand-dependent manner and enhances ligand-induced transcriptional activity of the receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Catalysis of the reaction: NADPH + H2O = NMNH + ADP."^^xsd:string) AnnotationAssertion(rdfs:label "NADPH pyrophosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Catalysis of the reaction: coenzyme A + H2O = 3',5'-ADP + 4'-phosphopantetheine."^^xsd:string) AnnotationAssertion(rdfs:label "CoA pyrophosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Interacting selectively and non-covalently with an anaphase-promoting complex. A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis."^^xsd:string) AnnotationAssertion(rdfs:label "anaphase-promoting complex binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "APC binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kd"^^xsd:string) "Catalysis of the four-electron reduction of dioxygen (O2) to water, coupled to generation of a proton electrochemical gradient across a membrane."^^xsd:string) AnnotationAssertion( "haem-copper terminal oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "heme-copper terminal oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.8"^^xsd:string) "heparan sulfate N-sulfotransferase activity"^^xsd:string) AnnotationAssertion( "desulfoheparin sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.8"^^xsd:string) "N-HSST activity"^^xsd:string) AnnotationAssertion( "heparin N-deacetylase/N-sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.8"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine."^^xsd:string) AnnotationAssertion( "heparitin N-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.8"^^xsd:string) "heparan sulfate 2-N-sulfotransferase activity"^^xsd:string) AnnotationAssertion( "heparitin N-sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.8"^^xsd:string) "3'-phosphoadenylylsulfate:N-desulfoheparin sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.8"^^xsd:string) "PAPS:N-desulfoheparin sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.8"^^xsd:string) "3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine N-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.8"^^xsd:string) "heparan sulfate N-deacetylase/N-sulfotransferase activity"^^xsd:string) AnnotationAssertion( "heparitin sulfotransferase activity"^^xsd:string) AnnotationAssertion( "heparin-glucosamine N-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.8"^^xsd:string) "3'-phosphoadenylyl-sulfate:N-desulfoheparin N-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.8"^^xsd:string) "N-desulfoheparin sulfotransferase activity"^^xsd:string) AnnotationAssertion( "heparin N-deacetylase/N-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.8"^^xsd:string) "PAPS:DSH sulfotransferase activity"^^xsd:string) AnnotationAssertion( "[heparan sulphate]-glucosamine N-sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.8"^^xsd:string) "N-heparan sulfate sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.8"^^xsd:string) "3'-phosphoadenylyl-sulfate:heparitin N-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.8"^^xsd:string) "heparin N-sulfotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[heparan sulfate]-glucosamine N-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.8"^^xsd:string) "glucosaminyl N-deacetylase/N-sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.135"^^xsd:string) "UDP-glucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.135"^^xsd:string) "UDPglucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.135"^^xsd:string) "Catalysis of the reaction: UDP-glucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein = UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein."^^xsd:string) AnnotationAssertion(rdfs:label "galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.135"^^xsd:string) "uridine diphosphate glucuronic acid:acceptor glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.135"^^xsd:string) "glucuronosyltransferase I activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.78"^^xsd:string) "acetyl-CoA:alpha-glucosaminide N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.78"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + heparan alpha-D-glucosaminide = CoA + heparan N-acetyl-alpha-D-glucosaminide."^^xsd:string) AnnotationAssertion( "heparin-alpha-glucosaminide N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "heparan-alpha-glucosaminide N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.78"^^xsd:string) "acetyl-CoA:heparan-alpha-D-glucosaminide N-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "bilirubin monoglucuronide glucuronyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "17-OH steroid UDPGT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "p-nitrophenol UDP-glucuronyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "UDPGT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "4-nitrophenol UDPGT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "4-nitrophenol UDP-glucuronyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "PNP-UDPGT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "uridine diphosphoglucuronate-estriol glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "UDP-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "3alpha-hydroxysteroid UDP-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "UDPGA-glucuronyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "bilirubin uridine diphosphoglucuronyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "1-naphthol-UDP-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "p-nitrophenol UDP-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "4-methylumbelliferone UDP-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "17beta-hydroxysteroid UDP-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "3-OH androgenic UDPGT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "bilirubin UDP-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "UDPGA transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "UDP-glucuronate-bilirubin glucuronyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "bilirubin UDPGT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "uridine 5'-diphosphoglucuronyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "UDP glucuronic acid transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "UDP glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "17-beta-hydroxysteroid UDP-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "UDP glucuronyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "estrone UDPglucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "GT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "p-nitrophenylglucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "UDP-glucuronyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "bilirubin glucuronyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "uridine diphosphoglucuronyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "UDP glucuronate-estradiol-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "p-hydroxybiphenyl UDP glucuronyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "uridine diphosphate glucuronyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "pnp-UDPGT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "1-naphthol glucuronyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "ciramadol UDP-glucuronyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "uridine diphosphoglucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "p-phenylphenol glucuronyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "morphine glucuronyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "estriol UDPglucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "4-hydroxybiphenyl UDP-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "UDP glucuronate-estriol glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.17"^^xsd:string) "phenyl-UDP-glucuronosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "[heparan sulfate]-sulfate lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "heparin-sulfate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.8"^^xsd:string) "heparitinase I"^^xsd:string) AnnotationAssertion( "heparin-sulphate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.8"^^xsd:string) "heparin-sulfate eliminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.8"^^xsd:string) "heparitinase II"^^xsd:string) AnnotationAssertion( "heparitin-sulfate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.8"^^xsd:string) "Catalysis of the elimination of sulfate; appears to act on linkages between N-acetyl-D-glucosamine and uronate. Product is an unsaturated sugar."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucuronate-2-sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.18"^^xsd:string) "polysaccharide-2-O-sulfo-D-glucuronate 2-sulfohydrolase activity"^^xsd:string) AnnotationAssertion( "glucuronate-2-sulphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.18"^^xsd:string) "glucurono-2-sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.18"^^xsd:string) "Catalysis of the hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.18"^^xsd:string) "chondro-2-sulfatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "coreceptor, soluble ligand activity"^^xsd:string) AnnotationAssertion(rdfs:label "coreceptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "coreceptor, insoluble ligand activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "heme lyase disulfide oxidoreductase activity"^^xsd:string) AnnotationAssertion( "protein disulphide oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein disulfide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "thioredoxin activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:DISULFOXRED-RXN"^^xsd:string) "Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds."^^xsd:string) AnnotationAssertion( "haem lyase disulphide oxidoreductase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "disulphide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:DISULFOXRED-RXN"^^xsd:string) "Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds."^^xsd:string) AnnotationAssertion(rdfs:label "disulfide oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peptide disulfide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "MetaCyc:DISULFOXRED-RXN"^^xsd:string) "Catalysis of the reaction: a peptide with reduced sulfide groups = a peptide with oxidized disulfide bonds."^^xsd:string) AnnotationAssertion( "peptide disulphide oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glutathione disulphide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor."^^xsd:string) AnnotationAssertion(rdfs:label "glutathione disulfide oxidoreductase activity"^^xsd:string) AnnotationAssertion( "glutaredoxin"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.18.1.2"^^xsd:string) "adrenodoxin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.2"^^xsd:string) "NADPH:adrenodoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.2"^^xsd:string) Annotation( "GOC:kd"^^xsd:string) "Catalysis of the reaction: oxidized adrenodoxin + NADPH + H+ = reduced adrenodoxin + NADP+."^^xsd:string) AnnotationAssertion(rdfs:label "NADPH-adrenodoxin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kd"^^xsd:string) "adrenodoxin-type ferredoxin reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.1.12"^^xsd:string) "NADPH2:trypanothione oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.12"^^xsd:string) "NADPH:trypanothione oxidoreductase activity"^^xsd:string) AnnotationAssertion( "trypanothione reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.12"^^xsd:string) "N(1),N(8)-bis(glutathionyl)spermidine reductase activity"^^xsd:string) AnnotationAssertion( "trypanothione-disulphide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.12"^^xsd:string) "Catalysis of the reaction: NADP+ + trypanothione = NADPH + H+ + trypanothione disulfide."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.12"^^xsd:string) "N1,N8-bis(glutathionyl)spermidine reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trypanothione-disulfide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.12"^^xsd:string) "trypanothione:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "leghemoglobin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.6"^^xsd:string) "ferric leghemoglobin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.6"^^xsd:string) "Catalysis of the reaction: NADPH + H+ + 2 ferrileghemoglobin = NADP+ + 2 ferroleghemoglobin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.6"^^xsd:string) "NAD(P)H:ferrileghemoglobin oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.18.1.1"^^xsd:string) "DPNH-rubredoxin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.1"^^xsd:string) "rubredoxin:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.1"^^xsd:string) "reduced nicotinamide adenine dinucleotide--rubredoxin reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "rubredoxin-NAD+ reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.1"^^xsd:string) "Catalysis of the reaction: reduced rubredoxin + NAD+ = oxidized rubredoxin + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.1"^^xsd:string) "rubredoxin--nicotinamide adenine dinucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.1"^^xsd:string) "rubredoxin--NAD reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.1"^^xsd:string) "NADH:rubredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion( "NADH:rubredoxin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.1"^^xsd:string) "NADH--rubredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.1"^^xsd:string) "dihydronicotinamide adenine dinucleotide--rubredoxin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.1"^^xsd:string) "NADH--rubredoxin reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "rubredoxin-NAD(P)+ reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.4"^^xsd:string) "Catalysis of the reaction: reduced rubredoxin + NAD(P)+ = oxidized rubredoxin + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.4"^^xsd:string) "NAD(P)--rubredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.4"^^xsd:string) "rubredoxin--nicotinamide adenine activity"^^xsd:string) AnnotationAssertion( "NADPH:rubredoxin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.4"^^xsd:string) "NAD(P)H--rubredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.4"^^xsd:string) "rubredoxin--nicotinamide adenine dinucleotide (phosphate) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.4"^^xsd:string) "rubredoxin:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.4"^^xsd:string) "dinucleotide phosphate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "rubredoxin-NADP reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.1.-"^^xsd:string) "Catalysis of the reaction: reduced rubredoxin + NADP+ = oxidized rubredoxin + NADPH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.6.2.5"^^xsd:string) "Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome c2 = NADP+ + 2 ferrocytochrome c2."^^xsd:string) AnnotationAssertion(rdfs:label "NADPH-cytochrome-c2 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.5"^^xsd:string) "NADPH:ferricytochrome-c2 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.5"^^xsd:string) "cytochrome c2 reductase (reduced nicotinamide adinine dinucleotide phosphate, NADPH)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.2.5"^^xsd:string) "reductase, cytochrome c2 (reduced nicotinamide adenine dinucleotide phosphate)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:7589982"^^xsd:string) "Catalysis of the transfer of electrons between pyridine nucleotides (obligatory two-electron carriers) and hemes or (2Fe-2S) centers (obligatory one-electron carriers) in respiration, photosynthesis, and many oxygenase systems."^^xsd:string) AnnotationAssertion(rdfs:label "phthalate dioxygenase reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.25"^^xsd:string) "Catalysis of the reaction: methane + NAD(P)H + H+ + O2 = methanol + NAD(P)+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "methane monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.25"^^xsd:string) "methane,NAD(P)H:oxygen oxidoreductase (hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.25"^^xsd:string) "methane hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "IUPHAR_GPCR:1274"^^xsd:string) "Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta3-adrenergic receptors."^^xsd:string) AnnotationAssertion( "beta3 adrenoceptor"^^xsd:string) AnnotationAssertion(rdfs:label "beta3-adrenergic receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with gastrin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "gastrin receptor activity"^^xsd:string) AnnotationAssertion( "cholecystokinin-B receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "secretin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with secretin to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "corticotrophin-releasing factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12032352"^^xsd:string) "Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Combining with thrombin to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state."^^xsd:string) AnnotationAssertion( "thrombin receptor activity, G-protein coupled"^^xsd:string) AnnotationAssertion(rdfs:label "thrombin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "purinoceptor type U"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) Annotation( "PMID:8537335"^^xsd:string) "Combining with UTP or UDP to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "uridine nucleotide receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stops, prevents or reduces the activity of alpha-amylase."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-amylase inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "transamidinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "amidinotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reversible transfer of an amidino group to an acceptor."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.4.1"^^xsd:string) "arginine-glycine transamidinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.4.1"^^xsd:string) "glycine transamidinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.4.1"^^xsd:string) "arginine-glycine amidinotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.4.1"^^xsd:string) "Catalysis of the reaction: L-arginine + glycine = L-ornithine + guanidinoacetate."^^xsd:string) AnnotationAssertion(rdfs:label "glycine amidinotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.4.1"^^xsd:string) "L-arginine:glycine amidinotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.4.2"^^xsd:string) "L-arginine:inosamine phosphate amidinotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.4.2"^^xsd:string) Annotation( "RHEA:13268"^^xsd:string) "Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol 4-phosphate + L-arginine = 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + L-ornithine."^^xsd:string) AnnotationAssertion( "inosamine-phosphate amidinotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "scyllo-inosamine-4-phosphate amidinotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.4.2"^^xsd:string) "L-arginine:1-amino-1-deoxy-scyllo-inositol-4-phosphate amidinotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.4.2"^^xsd:string) "L-arginine:inosamine-P-amidinotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.4.2"^^xsd:string) "inosamine-P amidinotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "ion transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dgf"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of an ion from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a inorganic cations with a valency of one from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage."^^xsd:string) AnnotationAssertion(rdfs:label "monovalent inorganic cation transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "proton transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydrogen ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of hydrogen ions from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of potassium ions (K+) from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "potassium ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "potassium transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "silver transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of silver (Ag) ions from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "silver ion transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of sodium ions (Na+) from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "sodium ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "sodium transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aluminum ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "aluminium ion transporter activity"^^xsd:string) AnnotationAssertion( "aluminium resistance permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of aluminum (Al) ions from one side of a membrane to the other."^^xsd:string) AnnotationAssertion( "aluminum resistance permease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcium ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dgf"^^xsd:string) "Catalysis of the transfer of calcium (Ca) ions from one side of a membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dgf"^^xsd:string) "Catalysis of the transfer of cadmium (Cd) ions from one side of a membrane to the other."^^xsd:string) AnnotationAssertion( "zinc, cadmium uptake permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "cadmium ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dgf"^^xsd:string) "Catalysis of the transfer of cobalt (Co) ions from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "cobalt ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "cobalt, zinc uptake permease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "copper uptake transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:9.A.12.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Cu+(out) = Cu+(in)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "high affinity copper transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "high affinity copper ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:9.A.11.1.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Cu2+(out) = Cu2+(in)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "low affinity iron ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:9.A.9.1.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Fe2+(out) = Fe2+(in)."^^xsd:string) AnnotationAssertion( "low affinity iron transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "ferric iron transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "high affinity ferric uptake transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "TC:9.A.10.1.1"^^xsd:string) "Catalysis of the transfer of Fe(III) from the outside of a cell to the inside of a cell across a membrane."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "ferrous iron transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lead ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of lead (Pb) ions from one side of a membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dgf"^^xsd:string) "Catalysis of the transfer of magnesium (Mg) ions from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "magnesium ion transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mercury ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of mercury (Hg) ions from one side of a membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of molybdate (MoO4 2-) ions from one side of a membrane to the other. Molybdate is the bivalent anion derived from molybdic acid."^^xsd:string) AnnotationAssertion(rdfs:label "molybdate ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "molybdate transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nickel cation transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of nickel (Ni) cations from one side of a membrane to the other."^^xsd:string) AnnotationAssertion( "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of vanadium (V) ions from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "vanadium ion transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "organic cation transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage."^^xsd:string) AnnotationAssertion(rdfs:label "inorganic anion transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "antimonite transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of antimonite from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of arsenite from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "arsenite transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bicarbonate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chlorate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:49709"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Catalysis of the transfer of chlorate, ClO3-, from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chloride transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of chloride ions from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(Annotation( "GOC:pr"^^xsd:string) "chloride ion transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of chromate from one side of a membrane to the other. Chromate is the anion of chromic acid, H2CrO4 (aq) or CrO3."^^xsd:string) AnnotationAssertion(rdfs:label "chromate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of cyanate, NCO-, the anion of cyanic acid, from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "cyanate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of iodide ions from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "iodide transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of nitrate ions (NO3-) from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "nitrate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "nitrite/nitrate porter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of nitrite (NO2-) ions from one side of a membrane to the other."^^xsd:string) AnnotationAssertion( "nitrite/nitrate porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "nitrite transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) "phosphate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "phosphate ion transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:48123"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of silicates from one side of a membrane to the other. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates."^^xsd:string) AnnotationAssertion(rdfs:label "silicate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sulfate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other."^^xsd:string) AnnotationAssertion( "sulfate permease activity"^^xsd:string) AnnotationAssertion( "sulphate transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of thiosulfate ions, S2O3(2-), from one side of a membrane to the other."^^xsd:string) AnnotationAssertion( "thiosulphate transporter activity"^^xsd:string) AnnotationAssertion( "thiosulfate permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiosulfate transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:30477"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of tellurite from one side of a membrane to the other. Tellurite is a salt of tellurous acid or an oxide of tellurium which occurs sparingly in tufts of white or yellowish crystals."^^xsd:string) AnnotationAssertion(rdfs:label "tellurite transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of hexose phosphate from one side of the membrane to the other. Hexose phosphates is any of a group of monophosphorylated aldoses with a chain of six carbon atoms in the molecule."^^xsd:string) AnnotationAssertion(rdfs:label "hexose phosphate transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of phosphoglycerates from one side of the membrane to the other. Phosphoglycerates are important intermediates in glycolysis and 3-phosphoglycerate is a precursor in serine biosynthesis."^^xsd:string) AnnotationAssertion(rdfs:label "phosphoglycerate transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphoenolpyruvate(out) + phosphate(in) = phosphoenolpyruvate(in) + phosphate(out)."^^xsd:string) AnnotationAssertion( "phosphoenolpyruvate/phosphate translocator"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10488230"^^xsd:string) "PPT"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoenolpyruvate:phosphate antiporter activity"^^xsd:string) AnnotationAssertion( "phosphoenolpyruvate transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of acetate from one side of the membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "acetate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "allantoate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the transfer of allantoate from one side of the membrane to the other. Allantoate is the end product of purine metabolism in mammals and some fish, formed form allantoin. It is widely distributed in plants as an important source of stored nitrogen."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of bile acid from one side of the membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine."^^xsd:string) AnnotationAssertion(rdfs:label "bile acid transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "canalicular bile acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "The directed movement of bile acid and bile salts out of a hepatocyte and into the bile canaliculus by means of an agent such as a transporter or pore. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bilirubin transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the transfer of bilirubin from one side of the membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of gluconate from one side of the membrane to the other. Gluconate is the aldonic acid derived from glucose."^^xsd:string) AnnotationAssertion(rdfs:label "gluconate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "L-idonate/D-gluconate:hydrogen symporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of lactate from one side of the membrane to the other. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices."^^xsd:string) AnnotationAssertion(rdfs:label "lactate transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of mevalonate from one side of the membrane to the other. Mevalonate is the anion of mevalonic acid; its (R)-enantiomer is a strategic intermediate derived from hydroxymethylglutaryl-CoA in the biosynthesis of polyprenyl compounds."^^xsd:string) AnnotationAssertion(rdfs:label "mevalonate transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxaloacetate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of oxaloacetate, the anion of oxobutanedioic acid, from one side of the membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "prostaglandin/thromboxane transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "prostaglandin transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of prostaglandins from one side of the membrane to the other. A prostaglandin is any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "uronic acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of uronic acid from one side of the membrane to the other. Uronic acids are any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of hexuronates from one side of the membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6."^^xsd:string) AnnotationAssertion(rdfs:label "hexuronate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of glucuronate from one side of the membrane to the other. Glucuronate is the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group."^^xsd:string) AnnotationAssertion(rdfs:label "glucuronate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of sialic acid from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "sialic acid transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "citrate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fumarate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of fumarate from one side of the membrane to the other. Fumarate is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate."^^xsd:string) AnnotationAssertion( "dicarboxylate (succinate/fumarate/malate) antiporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2-oxoglutarate transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the transfer of alpha-ketoglutarate from one side of the membrane to the other. Alpha-ketoglutarate (or oxoglutarate) is a compound with important roles in carbohydrate and amino acid metabolism, especially in transamination reactions and as a component of the TCA cycle."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-ketoglutarate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "dicarboxylate (succinate/fumarate/malate) antiporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "malate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of malate from one side of the membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "succinate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "dicarboxylate (succinate/fumarate/malate) antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of succinate, the dianion of ethane dicarboxylic acid, from one side of the membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sodium:dicarboxylate/tricarboxylate symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of tricarboxylic acids from one side of the membrane to the other. Tricarboxylic acid are organic acids with three COOH groups."^^xsd:string) AnnotationAssertion(rdfs:label "tricarboxylic acid transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "uric acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of urate from one side of the membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals."^^xsd:string) AnnotationAssertion(rdfs:label "urate transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sugar transporter"^^xsd:string) AnnotationAssertion(rdfs:label "carbohydrate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of carbohydrate from one side of the membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "monosaccharide transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a monosaccharide from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a pentose sugar, a monosaccharide with 5 carbon atoms, from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "pentose transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-arabinose from one side of the membrane to the other. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, etc."^^xsd:string) AnnotationAssertion(rdfs:label "L-arabinose transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of D-xylose from one side of the membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides."^^xsd:string) AnnotationAssertion(rdfs:label "D-xylose transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hexose transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of fucose from one side of the membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose."^^xsd:string) AnnotationAssertion(rdfs:label "fucose transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "http://www.biochem.purdue.edu/"^^xsd:string) "Catalysis of the transfer of alpha-glucosides from one side of the membrane to the other. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-glucoside transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucose-6-phosphate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of glucose-6-phosphate from one side of the membrane to the other. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "rhamnose transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of rhamnose from one side of the membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "disaccharide transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of disaccharide from one side of the membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of lactose from one side of the membrane to the other. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals."^^xsd:string) AnnotationAssertion( "lactose/glucose efflux transporter activity"^^xsd:string) AnnotationAssertion( "lactose permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "lactose transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of melibiose from one side of the membrane to the other. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose and occurs as a constituent of the trisaccharide raffinose or in the exudates and nectaries of a number of plants."^^xsd:string) AnnotationAssertion(rdfs:label "melibiose transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oligosaccharide transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of oligosaccharide from one side of the membrane to the other."^^xsd:string) AnnotationAssertion( "endosomal oligosaccharide transporter"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "raffinose transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "raffinose permease"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of raffinose from one side of the membrane to the other. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:18154"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of polysaccharides from one side of the membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically."^^xsd:string) AnnotationAssertion(rdfs:label "polysaccharide transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of beta-glucans from one side of the membrane to the other. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds."^^xsd:string) AnnotationAssertion(rdfs:label "beta-glucan transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "capsule polysaccharide transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of capsular-polysaccharides from one side of the membrane to the other. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi."^^xsd:string) AnnotationAssertion(rdfs:label "capsular polysaccharide transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of teichoic acid from one side of the membrane to the other. Teichoic acid is any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues."^^xsd:string) AnnotationAssertion(rdfs:label "teichoic acid transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a hexuronide from one side of the membrane to the other. Hexuronides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of a hexuronate."^^xsd:string) AnnotationAssertion(rdfs:label "hexuronide transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a glucuronosides from one side of the membrane to the other. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate."^^xsd:string) AnnotationAssertion( "glucuronide transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucuronoside transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyrimidine nucleotide-sugar transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a pyrimidine nucleotide-sugar from one side of the membrane to the other. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sugar/polyol channel activity"^^xsd:string) AnnotationAssertion(rdfs:label "polyol transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of a polyol from one side of the membrane to the other. A polyol is any polyhydric alcohol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "arabinitol transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of an arabitol from one side of the membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms."^^xsd:string) AnnotationAssertion(rdfs:label "arabitol transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycerol transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of glycerol from one side of the membrane to the other. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of glycerol-3-phosphate from one side of the membrane to the other. Glycerol-3-phosphate is a phosphoric monoester of glycerol."^^xsd:string) AnnotationAssertion(rdfs:label "glycerol-3-phosphate transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "propanediol transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of propanediol from one side of the membrane to the other. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "general amino acid permease activity"^^xsd:string) AnnotationAssertion( "hydroxy/aromatic amino acid permease activity"^^xsd:string) AnnotationAssertion( "amino acid permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group."^^xsd:string) AnnotationAssertion( "amino acid transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "amino acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "amino acid/choline transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acidic amino acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "acidic amino acid transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have a pH below 7."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aromatic amino acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "aromatic amino acid transporter activity"^^xsd:string) AnnotationAssertion( "hydroxy/aromatic amino acid permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of aromatic amino acids from one side of a membrane to the other. Aromatic amino acids have an aromatic ring."^^xsd:string) AnnotationAssertion( "valine/tyrosine/tryptophan permease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "basic amino acid transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of basic amino acids from one side of a membrane to the other. Acidic amino acids have a pH above 7."^^xsd:string) AnnotationAssertion(rdfs:label "basic amino acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "basic amino acid permease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "neutral amino acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have a pH of 7."^^xsd:string) AnnotationAssertion( "neutral amino acid transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-amino acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:jsg"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids."^^xsd:string) AnnotationAssertion( "L-amino acid transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-alanine transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-alanine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "GOC:jsg"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-alanine from one side of a membrane to the other. L-alanine is the L-enantiomer of 2-aminopropanoic acid."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arginine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the stereospecific transfer of arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane."^^xsd:string) AnnotationAssertion( "L-arginine transporter activity"^^xsd:string) AnnotationAssertion( "arginine permease activity"^^xsd:string) AnnotationAssertion( "histidine/arginine/lysine/ornithine porter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-asparagine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "L-asparagine transporter activity"^^xsd:string) AnnotationAssertion( "asparagine/glutamine permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "GOC:jsg"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-asparagine from one side of a membrane to the other. L-asparagine is the L-enantiomer of alpha-aminosuccinamic acid."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glutamate/aspartate:sodium symporter activity"^^xsd:string) AnnotationAssertion( "L-aspartate transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-aspartate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "glutamate/aspartate porter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-aspartate from one side of a membrane to the other. L-aspartate is the anion derived from aspartic acid."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-cystine from one side of a membrane to the other."^^xsd:string) AnnotationAssertion( "L-cystine transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-cystine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "cystine/diaminopimelate porter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "gamma-aminobutyric acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "4-aminobutanoate transporter activity"^^xsd:string) AnnotationAssertion( "betaine/GABA:sodium symporter activity"^^xsd:string) AnnotationAssertion( "4-aminobutyrate transporter activity"^^xsd:string) AnnotationAssertion( "GABA transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-glutamine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-glutamine from one side of a membrane to the other. L-glutamine is 2-amino-4-carbamoylbutanoic acid."^^xsd:string) AnnotationAssertion( "asparagine/glutamine permease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glycine betaine/proline porter activity"^^xsd:string) AnnotationAssertion( "glycine transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid."^^xsd:string) AnnotationAssertion( "proline/glycine/betaine:hydrogen/sodium symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-isoleucine from one side of a membrane to the other. L-isoleucine is (2R*,3R*)-2-amino-3-methylpentanoic acid."^^xsd:string) AnnotationAssertion( "isoleucine/valine:sodium symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-isoleucine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "leucine/isoleucine/valine porter activity"^^xsd:string) AnnotationAssertion( "L-isoleucine transporter activity"^^xsd:string) AnnotationAssertion( "leucine/valine/isoleucine permease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "histidine/arginine/lysine/ornithine porter activity"^^xsd:string) AnnotationAssertion( "lysine permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "L-lysine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "L-lysine permease"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-leucine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-leucine from one side of a membrane to the other. L-leucine is 2-amino-4-methylpentanoic acid."^^xsd:string) AnnotationAssertion( "L-leucine transporter activity"^^xsd:string) AnnotationAssertion( "leucine/valine/isoleucine permease activity"^^xsd:string) AnnotationAssertion( "leucine/isoleucine/valine porter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-methionine transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-methionine from one side of a membrane to the other. L-methionine is 2-amino-4-(methylthio)butanoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "L-methionine transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-phenylalanine transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-phenylalanine from one side of a membrane to the other. L-phenylalanine is 2-amino-3-phenylpropanoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "L-phenylalanine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "L-phenylalanine permease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-proline transporter activity"^^xsd:string) AnnotationAssertion( "L-proline permease activity"^^xsd:string) AnnotationAssertion( "glycine betaine/proline porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-proline transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "proline/glycine/betaine:hydrogen/sodium symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-proline from one side of a membrane to the other. L-proline is pyrrolidine-2-carboxylic acid."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-serine permease activity"^^xsd:string) AnnotationAssertion( "L-serine transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-serine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "threonine/serine:sodium symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:jsg"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-serine from one side of a membrane to the other. L-serine is the L-enantiomer of 2-amino-3-hydroxypropanoic acid."^^xsd:string) AnnotationAssertion( "serine transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "threonine/serine:sodium symporter activity"^^xsd:string) AnnotationAssertion( "L-threonine permease activity"^^xsd:string) AnnotationAssertion( "L-threonine transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-threonine from one side of a membrane to the other. L-threonine is (2R*,3S*)-2-amino-3-hydroxybutanoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "L-threonine transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-tryptophan transporter activity"^^xsd:string) AnnotationAssertion( "valine/tyrosine/tryptophan permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-tryptophan transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid."^^xsd:string) AnnotationAssertion( "L-tryptophan permease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion( "peptide uptake permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "peptide transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oligopeptide transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of oligopeptides into, out of or within a cell, or between cells. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glycine betaine/proline porter activity"^^xsd:string) AnnotationAssertion( "betaine/GABA:sodium symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "amino-acid betaine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "proline/glycine/betaine:hydrogen/sodium symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of betaine, the N-trimethyl derivative of an amino acid, from one side of the membrane to the other."^^xsd:string) AnnotationAssertion( "betaine transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methylammonium transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of methylammonium, CH3NH2, into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "polyamine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of polyamines, organic compounds containing two or more amino groups, from one side of the membrane to the other."^^xsd:string) AnnotationAssertion( "amine/amide/polyamine channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "urea transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "urea transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of urea cross a membrane into, out of or within a cell, or between cells. Urea is the water soluble compound H2N-CO-NH2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "nucleobase transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Catalysis of the transfer of adenine, 6-aminopurine, from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "adenine transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Catalysis of the transfer of guanine, 2-amino-6-hydroxypurine, from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "guanine transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Catalysis of the transfer of cytosine, 4-amino-2-hydroxypyrimidine from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "cytosine transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Catalysis of the transfer of uracil, 2,4-dioxopyrimidine, from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "uracil transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "uracil/uridine permease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a purine nucleoside, a purine base covalently bonded to a ribose or deoxyribose sugar, from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "purine nucleoside transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cytidine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Catalysis of the transfer of cytidine, cytosine riboside, from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "uridine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Catalysis of the transfer of uridine, uracil riboside, from one side of a membrane to the other."^^xsd:string) AnnotationAssertion( "uracil/uridine permease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "pyrimidine nucleoside transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "nucleotide transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "purine nucleotide transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of ADP, adenosine diphosphate, from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "ADP transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "pyrimidine nucleotide transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of protein-DNA complexes from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "DNA-protein complex transmembrane transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-DNA complex transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "choline transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "choline permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of choline from one side of the membrane to the other. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine."^^xsd:string) AnnotationAssertion( "amino acid/choline transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "LPS transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of lipopolysaccharides from one side of the membrane to the other. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide."^^xsd:string) AnnotationAssertion(rdfs:label "lipopolysaccharide transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of serotonin from one side of the membrane to the other. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems."^^xsd:string) AnnotationAssertion(rdfs:label "serotonin transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of biopterin into, out of or within a cell, or between cells. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme."^^xsd:string) AnnotationAssertion(rdfs:label "biopterin transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "biotin transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of biotin into, out of or within a cell, or between cells. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions."^^xsd:string) AnnotationAssertion( "vitamin B7 transporter activity"^^xsd:string) AnnotationAssertion( "vitamin H transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of carnitine across a membrane. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane."^^xsd:string) AnnotationAssertion(rdfs:label "carnitine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "vitamin Bt transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:17387"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of acyl carnitine across a membrane. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane."^^xsd:string) AnnotationAssertion( "acylcarnitine transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "acyl carnitine transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "coenzyme A transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "coenzyme A transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of coenzyme A across a membrane into, out of or within a cell, or between cells. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "vitamin C transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:38290"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of L-ascorbate into, out of or within a cell, or between cells. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species."^^xsd:string) AnnotationAssertion(rdfs:label "L-ascorbic acid transporter activity"^^xsd:string) AnnotationAssertion( "L-ascorbate transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of flavin-adenine dinucleotide (FAD) across a membrane into, out of or within a cell, or between cells. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form."^^xsd:string) AnnotationAssertion(rdfs:label "FAD transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "flavin adenine dinucleotide transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "flavin-adenine dinucleotide transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "FAD transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5-formyltetrahydrofolate transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, into, out of, within, or between cells."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "heme transporter activity"^^xsd:string) AnnotationAssertion( "haem transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0721662544"^^xsd:string) "Enables the directed movement of pantothenate across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods."^^xsd:string) AnnotationAssertion(rdfs:label "pantothenate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "vitamin B5 transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "pantothenate transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of thiamine from one side of the membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver."^^xsd:string) AnnotationAssertion( "thiamine permease activity"^^xsd:string) AnnotationAssertion( "thiamin permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "thiamin transmembrane transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiamine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "vitamin B1 transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom, into, out of or within a cell."^^xsd:string) AnnotationAssertion( "vitamin B12 transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "cobalamin transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "multidrug transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "drug transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "multidrug efflux pump activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of a drug from one side of a membrane to the other. A drug is any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease."^^xsd:string) AnnotationAssertion( "multidrug, alkane resistant pump activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "amiloride transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of amiloride into, out of or within a cell, or between cells. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:40036"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Enables the directed movement of aminotriazole into, out of or within a cell, or between cells. Aminotriazole is an effective weed killer that also possesses some antithyroid activity."^^xsd:string) AnnotationAssertion(rdfs:label "aminotriazole transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:3015"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Enables the directed movement of benomyl into, out of or within a cell, or between cells. Benomyl, methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate, is a systemic agricultural fungicide used for control of certain fungal diseases of stone fruit."^^xsd:string) AnnotationAssertion(rdfs:label "benomyl transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of cycloheximide into, out of or within a cell, or between cells. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes."^^xsd:string) AnnotationAssertion(rdfs:label "cycloheximide transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:46081"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Enables the directed movement of fluconazole into, out of or within a cell, or between cells. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections."^^xsd:string) AnnotationAssertion(rdfs:label "fluconazole transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fatty acid transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of fatty acids into, out of or within a cell, or between cells. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of a fatty acyl group into, out of or within a cell, or between cells. A fatty acyl group is any acyl group derived from a fatty acid."^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "fatty acyl transporter activity"^^xsd:string) AnnotationAssertion( "peroxisomal fatty acyl transporter"^^xsd:string) AnnotationAssertion(rdfs:label "fatty-acyl group transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of aminophospholipids into, out of or within a cell, or between cells. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group."^^xsd:string) AnnotationAssertion(rdfs:label "aminophospholipid transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of sterols into, out of or within a cell, or between cells. Sterol are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."^^xsd:string) AnnotationAssertion(rdfs:label "sterol transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Transport systems of this type catalyze facilitated diffusion of water (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism."^^xsd:string) AnnotationAssertion(rdfs:label "water channel activity"^^xsd:string) AnnotationAssertion( "aquaporin"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of facilitated diffusion of ammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism."^^xsd:string) AnnotationAssertion(rdfs:label "ammonium channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydrogen ion channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of facilitated diffusion of a hydrogen ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of facilitated diffusion of glycerol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism."^^xsd:string) AnnotationAssertion(rdfs:label "glycerol channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of facilitated diffusion of propanediol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism."^^xsd:string) AnnotationAssertion(rdfs:label "propanediol channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methylammonium channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of facilitated diffusion of methylammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Methylammonium is CH3NH2."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "urea channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of facilitated diffusion of urea (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:rb"^^xsd:string) "Catalysis of energy-independent facilitated diffusion, mediated by passage of proteins through a transmembrane aqueous pore or channel."^^xsd:string) AnnotationAssertion(rdfs:label "protein channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "channel/pore class transporter activity"^^xsd:string) AnnotationAssertion( "nonselective channel activity"^^xsd:string) AnnotationAssertion(rdfs:label "channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:1.-.-.-.-"^^xsd:string) "Catalysis of energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules."^^xsd:string) AnnotationAssertion( "pore activity"^^xsd:string) AnnotationAssertion( "pore class transporter activity"^^xsd:string) AnnotationAssertion( "channel-forming toxin activity"^^xsd:string) AnnotationAssertion( "alpha-type channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient."^^xsd:string) AnnotationAssertion(rdfs:label "calcium-activated potassium channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel. An outwardly rectifying current-voltage relation is one where at any given driving force the outward flow of K+ ions exceeds the inward flow for the opposite driving force."^^xsd:string) AnnotationAssertion(rdfs:label "outward rectifier potassium channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ATP-activated inward rectifier potassium channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by ATP. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "organellar voltage-dependent chloride channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a chloride ion by a voltage-gated channel. The membrane is an organellar membrane."^^xsd:string) AnnotationAssertion( "organellar voltage gated chloride channel activity"^^xsd:string) AnnotationAssertion(rdfs:label "organellar voltage-gated chloride channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "stretch-activated, cation-selective, calcium channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:sart"^^xsd:string) "ionotropic receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "ligand-gated ion channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "kainate selective glutamate receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:10049997"^^xsd:string) Annotation( "PMID:8804111"^^xsd:string) "An ionotropic glutamate receptor activity that exhibits fast gating by glutamate, acts by opening a cation channel permeable to sodium and potassium, and for which kainate is an agonist."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion(rdfs:label "calcium-release channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) Annotation( "PMID:15788710"^^xsd:string) "A ligand-gated ion channel activity which transports calcium in response to emptying of intracellular calcium stores."^^xsd:string) AnnotationAssertion(rdfs:label "store-operated calcium channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:fj"^^xsd:string) "epithelial sodium channel"^^xsd:string) AnnotationAssertion(Annotation( "GOC:fj"^^xsd:string) "ASIC activity"^^xsd:string) AnnotationAssertion(rdfs:label "ligand-gated sodium channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion(Annotation( "GOC:fj"^^xsd:string) "acid-sensing ion channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:fj"^^xsd:string) "amiloride-sensitive sodium channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.1.1.13"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose(out) = fructose(in)."^^xsd:string) AnnotationAssertion(rdfs:label "fructose uniporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "outer membrane exporter porin"^^xsd:string) AnnotationAssertion( "porin"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "PMID:10839820"^^xsd:string) Annotation( "TC:1.B.1.-.-"^^xsd:string) "Catalysis of the transfer of substances, sized less than 1000 Da, from one side of the membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria."^^xsd:string) AnnotationAssertion(rdfs:label "porin activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "multidrug endosomal transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "coupled carrier"^^xsd:string) AnnotationAssertion( "secondary carrier-type facilitators"^^xsd:string) AnnotationAssertion( "heavy metal ion porter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "PMID:10839820"^^xsd:string) "Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport."^^xsd:string) AnnotationAssertion( "porter activity"^^xsd:string) AnnotationAssertion( "ion-gradient-driven energizer activity"^^xsd:string) AnnotationAssertion( "galactose/glucose (methylgalactoside) porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "secondary active transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "porters"^^xsd:string) AnnotationAssertion( "electrochemical potential-driven transporter activity"^^xsd:string) AnnotationAssertion( "active transporter"^^xsd:string) AnnotationAssertion( "energizer of outer membrane receptor-mediated transport activity"^^xsd:string) AnnotationAssertion( "nitrite/nitrate porter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "uniport"^^xsd:string) AnnotationAssertion( "single-species transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "PMID:10839820"^^xsd:string) "Catalysis of the transport of a single molecular species across a membrane; transport is independent of the movement of any other molecular species."^^xsd:string) AnnotationAssertion( "facilitated diffusion carrier"^^xsd:string) AnnotationAssertion(rdfs:label "uniporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "porter activity"^^xsd:string) AnnotationAssertion( "symport"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "PMID:10839820"^^xsd:string) "Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy."^^xsd:string) AnnotationAssertion( "cotransporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "symporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "solute:cation symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(out) = solute(in) + cation(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "heavy metal ion:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "high affinity metal ion uptake transporter activity"^^xsd:string) AnnotationAssertion( "proline/glycine/betaine:hydrogen/sodium symporter activity"^^xsd:string) AnnotationAssertion( "solute:proton symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(out) = solute(in) + H+(in)."^^xsd:string) AnnotationAssertion( "low affinity metal ion uptake transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "solute:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "L-idonate/D-gluconate:hydrogen symporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "anion:cation symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.14.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion(out) + cation(out) = anion(in) + cation(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "antiporter activity"^^xsd:string) AnnotationAssertion( "countertransporter activity"^^xsd:string) AnnotationAssertion( "porter"^^xsd:string) AnnotationAssertion( "exchange transporter activity"^^xsd:string) AnnotationAssertion( "antiport"^^xsd:string) AnnotationAssertion( "solute:solute antiporter activity"^^xsd:string) AnnotationAssertion( "exchanger"^^xsd:string) AnnotationAssertion( "solute:solute exchange"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "PMID:10839820"^^xsd:string) "Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "solute:cation antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(in) = solute(in) + cation(out)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "solute:proton antiporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "solute:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion( "L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out)."^^xsd:string) AnnotationAssertion( "bicarbonate:chloride antiporter"^^xsd:string) AnnotationAssertion( "anion exchanger activity"^^xsd:string) AnnotationAssertion(rdfs:label "anion:anion antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "galactose, glucose uniporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.1.12"^^xsd:string) Annotation( "TC:2.A.1.1.4"^^xsd:string) Annotation( "TC:2.A.1.1.6"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) = glucose(in)."^^xsd:string) AnnotationAssertion(rdfs:label "glucose uniporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sialate:cation symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.14.10"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + cation(out) = sialate(in) + cation(in)."^^xsd:string) AnnotationAssertion( "sialate/cation symporter activity"^^xsd:string) AnnotationAssertion( "cation:sialate symporter activity"^^xsd:string) AnnotationAssertion( "cation/sialate symporter activity"^^xsd:string) AnnotationAssertion( "sialate transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "drug:proton antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.2.-"^^xsd:string) Annotation( "TC:2.A.1.3.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + drug(in) = H+(in) + drug(out)."^^xsd:string) AnnotationAssertion(rdfs:label "drug:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion( "carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "amiloride:proton antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.2.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + amiloride(in) = H+(in) + amiloride(out)."^^xsd:string) AnnotationAssertion(rdfs:label "amiloride:hydrogen antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cycloheximide:proton antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.2.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + cycloheximide(in) = H+(in) + cycloheximide(out)."^^xsd:string) AnnotationAssertion(rdfs:label "cycloheximide:hydrogen antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "benomyl:proton antiporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "benomyl:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.2.6"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + benomyl(in) = H+(in) + benomyl(out)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.1.2.11"^^xsd:string) Annotation( "TC:2.A.1.2.12"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + monoamine(in) = H+(in) + monoamine(out)."^^xsd:string) AnnotationAssertion( "monoamine:proton antiporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "monoamine:hydrogen antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "polyamine:proton antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.2.16"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out)."^^xsd:string) AnnotationAssertion(rdfs:label "polyamine:hydrogen antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fluconazole:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.2.17"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + fluconazole(in) = H+(in) + fluconazole(out)."^^xsd:string) AnnotationAssertion( "fluconazole:proton antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "aminotriazole:proton antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.3.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + aminotriazole(in) = H+(in) + aminotriazole(out)."^^xsd:string) AnnotationAssertion(rdfs:label "aminotriazole:hydrogen antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "organophosphate:inorganic phosphate antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.4.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organophosphate(out) + inorganic phosphate(in) = organophosphate(in) + inorganic phosphate(out)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phosphate:proton symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.9.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphate(out) + H+(out) = phosphate(in) + H+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "phosphate:hydrogen symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inorganic solute uptake transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "inorganic uptake permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of an inorganic solute from the outside of a cell to the inside of the cell across a membrane."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sodium:inorganic phosphate symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.14.6"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + inorganic phosphate(out) = Na+(in) + inorganic phosphate(in)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) Annotation( "TC:2.A.29.4.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphate (cyt) + H+ (cyt) = phosphate (mitochondrion) + H+ (mitochondrion)."^^xsd:string) AnnotationAssertion(rdfs:label "phosphate ion carrier activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sodium-dependent phosphate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other, requiring sodium ions."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "secondary active oligopeptide transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of an oligopeptide or oligopeptides from one side of the membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction."^^xsd:string) AnnotationAssertion( "oligopeptide porter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "peptide-acetyl-CoA transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of peptide-acetyl-CoA from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport."^^xsd:string) AnnotationAssertion(rdfs:label "peptide-acetyl-CoA secondary active transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acetyl-CoA:CoA antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.25.1"^^xsd:string) "Catalysis of the reaction: acetyl-CoA(out) + CoA(in) = acetyl-CoA(in) + CoA(out)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cationic amino acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a positively charged amino acid from one side of the membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.3.8.5"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cystine(out) + glutamate(in) = cystine(in) + glutamate(out)."^^xsd:string) AnnotationAssertion(rdfs:label "cystine:glutamate antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cystinosin"^^xsd:string) AnnotationAssertion( "lysosomal cystine transporter"^^xsd:string) AnnotationAssertion( "cystine porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "cystine secondary active transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of cystine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "high affinity glutamine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "high affinity glutamine permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the high affinity transfer of glutamine from one side of the membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "peptide:proton symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "peptide:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "TC:2.A.17.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: peptide(out) + H+(out) = peptide(in) + H+(in). Catalysis of the transfer of a peptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by hydrogen ion movement."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of oligopeptide from one side of the membrane to the other. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages."^^xsd:string) AnnotationAssertion(rdfs:label "high affinity oligopeptide transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "zinc efflux active transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "zinc efflux permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:2.A.4.1.4"^^xsd:string) Annotation( "TC:2.A.4.2.3"^^xsd:string) "Catalysis of the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane: Zn2+(out) = Zn2+(in). The activity is driven by proton motive force."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "siderochrome-iron transporter activity"^^xsd:string) AnnotationAssertion( "iron-siderophore transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.16.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(out) + H+(out) = siderophore-iron(in) + H+(in)."^^xsd:string) AnnotationAssertion( "siderophore-iron transmembrane transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "siderophore transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ferrioxamine uptake transmembrane transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "siderophore uptake transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "siderochrome-iron (ferrioxamine) uptake transporter"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.16.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(ferrioxamine)(out) + H+(out) = siderophore-iron(ferrioxamine)(in) + H+(in)."^^xsd:string) AnnotationAssertion( "siderophore-iron uptake transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.1.16.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric enterobactin(out) + H+(out) = ferric enterobactin(in) + H+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "ferric enterobactin:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "ferric-enterobactin:proton symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ferric triacetylfusarinine C:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.16.3"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric triacetylfusarinine C(out) + H+(out) = ferric triacetylfusarinine C(in) + H+(in)."^^xsd:string) AnnotationAssertion( "ferric triacetylfusarinine C:proton symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sodium-independent organic anion transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Catalysis of the transfer of organic anions from one side of a membrane to the other, in a sodium independent manner."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thyroid hormone transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of thyroid hormones from one side of the membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methotrexate transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "bilitranslocase"^^xsd:string) AnnotationAssertion(rdfs:label "bilirubin secondary active transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of bilirubin from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport."^^xsd:string) AnnotationAssertion( "bilirubin porter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "secondary active sterol transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of sterol from one side of the membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction."^^xsd:string) AnnotationAssertion( "sterol porter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Catalysis of the movement of a monocarboxylate, any compound containing a single carboxyl group (COOH or COO-), by uniport, symport or antiport across a membrane by a carrier-mediated mechanism."^^xsd:string) AnnotationAssertion(rdfs:label "secondary active monocarboxylate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "monocarboxylate porter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acetate:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "acetate:proton symporter activity"^^xsd:string) AnnotationAssertion( "hydrogen:acetate symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.44.4.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: acetate(out) + H+(out) = acetate(in) + H+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.47.1.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations."^^xsd:string) AnnotationAssertion(rdfs:label "low affinity sodium:dicarboxylate symporter activity"^^xsd:string) AnnotationAssertion( "low affinity sodium:dicarboxylate cotransporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.47.1.4"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations."^^xsd:string) AnnotationAssertion(rdfs:label "high affinity sodium:dicarboxylate symporter activity"^^xsd:string) AnnotationAssertion( "high affinity sodium:dicarboxylate cotransporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dicarboxylate:inorganic phosphate antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.29.2.3"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + inorganic phosphate(in) = dicarboxylate(in) + inorganic phosphate(out)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "malate:proton symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.16.2.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + H+(out) = malate(in) + H+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "malate:hydrogen symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxoglutarate:malate antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.29.2.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: oxoglutarate(out) + malate(in) = oxoglutarate(in) + malate(out)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcium:cation antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.19.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + cation(out) = Ca2+(out) + cation(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "calcium:proton antiporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "calcium:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.19.2.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "proline/glycine/betaine:hydrogen/sodium symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "solute:sodium symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + Na+(out) = solute(in) + Na+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.21.3.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + Na+(out) = glucose(in) + Na+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "galactose:sodium symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "monovalent anion:sodium symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.21.5.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent anion(out) + Na+(out) = monovalent anion(in) + Na+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.22.2.3"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral/cationic amino acid(out) + Na+(out) + Cl-(out) = neutral/cationic amino acid(in) + Na+(in) + Cl-(in)."^^xsd:string) AnnotationAssertion(rdfs:label "neutral, cationic amino acid:sodium:chloride symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "glycine:sodium symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.30.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation(out) + Cl-(out) = cation(in) + Cl-(in)."^^xsd:string) AnnotationAssertion(rdfs:label "cation:chloride symporter activity"^^xsd:string) AnnotationAssertion( "cation:chloride cotransporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sodium:chloride symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.30.4.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + Cl-(out) = Na+(in) + Cl-(in)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.30.5.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Cl-(out) = K+(in) + Cl-(in)."^^xsd:string) AnnotationAssertion(rdfs:label "potassium:chloride symporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "high affinity sulphate permease activity"^^xsd:string) AnnotationAssertion( "high affinity sulfate permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the secondary active high affinity transfer of sulfate from one side of the membrane to the other. Secondary active transport is catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport. In high affinity transport the transporter is able to bind thesolute even if it is only present at very low concentrations."^^xsd:string) AnnotationAssertion(rdfs:label "high affinity sulfate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.47.1.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + Na+(out) = sulfate(in) + Na+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "sodium:sulfate symporter activity"^^xsd:string) AnnotationAssertion( "sodium:sulfate cotransporter activity"^^xsd:string) AnnotationAssertion( "sodium:sulphate symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.53.2.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + bicarbonate(in) = sulfate(in) + bicarbonate(out)."^^xsd:string) AnnotationAssertion( "sulphate:bicarbonate antiporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfate:bicarbonate antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "pH-dependent sodium:proton antiporter activity"^^xsd:string) AnnotationAssertion( "sodium:hydrogen exchange activity"^^xsd:string) AnnotationAssertion(rdfs:label "sodium:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion( "pH-dependent sodium:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion( "sodium/hydrogen antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.35.1.1"^^xsd:string) Annotation( "TC:2.A.36.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out)."^^xsd:string) AnnotationAssertion( "sodium:proton antiporter activity"^^xsd:string) AnnotationAssertion( "sodium:hydrogen exchanger"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.37.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in)."^^xsd:string) AnnotationAssertion( "potassium:proton antiporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "potassium:hydrogen antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "potassium:proton symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.38.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + H+(out) = K+(in) + H+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "potassium:hydrogen symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:2.A.72.2.-"^^xsd:string) "Catalysis of the transfer of potassium from the outside of a cell to the inside of the cell across a membrane: K+(out) + energy = K+(in)."^^xsd:string) AnnotationAssertion( "potassium uptake permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "potassium uptake transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyrimidine- and adenine-specific:sodium symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.41.2.3"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (pyrimidine nucleoside or adenine)(out) + Na+(out) = (pyrimidine nucleoside or adenine)(in) + Na+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.41.2.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: purine(out) + Na+(out) = nucleoside(in) + Na+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "purine-specific nucleoside:sodium symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nucleobase:cation symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleobase(out) + cation(out) = nucleobase(in) + cation(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uridine(out) + H+(out) = uridine(in) + H+(in)."^^xsd:string) AnnotationAssertion( "nucleoside (uridine) permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "uridine:hydrogen ion symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "equilibrative nucleoside transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10353709"^^xsd:string) Annotation( "PMID:11749958"^^xsd:string) Annotation( "PMID:12446811"^^xsd:string) "Catalysis of the transfer of a nucleoside, from one side of a membrane to the other, down the concentration gradient."^^xsd:string) AnnotationAssertion(rdfs:label "nucleoside transmembrane transporter activity, down a concentration gradient"^^xsd:string) AnnotationAssertion( "equilibrative nucleoside transmembrane transporter, nitrobenzyl-thioinosine-sensitive activity"^^xsd:string) AnnotationAssertion( "equilibrative nucleoside transmembrane transporter, nitrobenzyl-thioinosine-insensitive activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "high affinity secondary active ammonium transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "primary active transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "primary active transporter"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:3.-.-.-.-"^^xsd:string) "Catalysis of the transfer of a solute from one side of the membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is powered by a primary energy source. Primary energy sources known to be coupled to transport are chemical, electrical and solar sources."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "low affinity secondary active ammonium transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "low affinity ammonium transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport. In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "urea active transmembrane transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "urea:sodium symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.21.6.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: urea(out) + Na+(out) = urea(in) + Na+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thiamine uptake transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "thiamin uptake transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of thiamine from the outside of a cell to the inside across a membrane."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "P-P-bond-hydrolysis-driven transporters"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:3.A.-.-.-"^^xsd:string) "Primary active transport of a solute across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source."^^xsd:string) AnnotationAssertion(rdfs:label "P-P-bond-hydrolysis-driven transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "monosaccharide-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "monosaccharide-importing ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.17"^^xsd:string) "ATP phosphohydrolase (monosaccharide-importing)"^^xsd:string) AnnotationAssertion( "monosaccharide ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.17"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monosaccharide(out) = ADP + phosphate + monosaccharide(in). Ribose, xylose, arabinose, galactose and methylgalactoside are imported."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ferric transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.30"^^xsd:string) "ATP phosphohydrolase (ferric-ion-transporting)"^^xsd:string) AnnotationAssertion(rdfs:label "ferric-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "ferric ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.30"^^xsd:string) "Fe3+-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.30"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Fe3+(out) = ADP + phosphate + Fe3+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "manganese transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.35"^^xsd:string) "ATP phosphohydrolase (manganese-importing)"^^xsd:string) AnnotationAssertion(rdfs:label "manganese-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.35"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mn2+(out) = ADP + phosphate + Mn2+(in)."^^xsd:string) AnnotationAssertion( "manganese ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.35"^^xsd:string) "ABC-type manganese permease complex"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.36"^^xsd:string) "ATP phosphohydrolase (taurine-importing)"^^xsd:string) AnnotationAssertion( "taurine (2-aminoethane sulfonate) porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "taurine-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.36"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + taurine(out) = ADP + phosphate + taurine(in)."^^xsd:string) AnnotationAssertion( "taurine ABC transporter"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.29"^^xsd:string) "ATP phosphohydrolase (molybdate-importing)"^^xsd:string) AnnotationAssertion(rdfs:label "molybdate transmembrane-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "molybdate ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.29"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + molybdate(out) = ADP + phosphate + molybdate(in)."^^xsd:string) AnnotationAssertion( "molybdate transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.29"^^xsd:string) "molybdate-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "molybdate porter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "nickel porter activity"^^xsd:string) AnnotationAssertion( "nickel transporting ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nickel-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "nickel ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.24"^^xsd:string) "ATP phosphohydrolase (nickel-importing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.24"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ni2+(out) = ADP + phosphate + Ni2+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nitrate transmembrane-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "nitrate ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.26"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nitrate(out) = ADP + phosphate + nitrate(in)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.26"^^xsd:string) "nitrate-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "nitrate transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.26"^^xsd:string) "ATP phosphohydrolase (nitrate-importing)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.27"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphate(out) = ADP + phosphate + phosphate(in)."^^xsd:string) AnnotationAssertion( "phosphate porter activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.27"^^xsd:string) "ATP phosphohydrolase (phosphate-importing)"^^xsd:string) AnnotationAssertion(rdfs:label "phosphate ion transmembrane-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.27"^^xsd:string) "phosphate-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "phosphate transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.27"^^xsd:string) "ABC phosphate transporter activity"^^xsd:string) AnnotationAssertion( "phosphate ABC transporter"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.28"^^xsd:string) "ATP phosphohydrolase (phosphonate-transporting)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.28"^^xsd:string) "phosphonate-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "phosphonate transporting ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "organic phosphonate transmembrane-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "phosphonate ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.28"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphonate(out) = ADP + phosphate + phosphonate(in). A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "polyamine ABC transporter"^^xsd:string) AnnotationAssertion( "polyamine-importing ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.31"^^xsd:string) "ATP phosphohydrolase (polyamine-importing) activity"^^xsd:string) AnnotationAssertion(rdfs:label "polyamine-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.31"^^xsd:string) "Catalysis of the reaction: ATP + H2O + polyamine(out) = ADP + phosphate + polyamine(in)."^^xsd:string) AnnotationAssertion( "polyamine porter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glycine betaine/proline porter activity"^^xsd:string) AnnotationAssertion( "quaternary-amine-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.32"^^xsd:string) "Catalysis of the reaction: ATP + H2O + quaternary amine(out) = ADP + phosphate + quaternary amine(in)."^^xsd:string) AnnotationAssertion( "quaternary amine uptake transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.32"^^xsd:string) "ATP phosphohydrolase (quaternary-amine-importing) activity"^^xsd:string) AnnotationAssertion( "quaternary-ammonium-compound ABC transporter"^^xsd:string) AnnotationAssertion(rdfs:label "quaternary-ammonium-compound-transporting ATPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sulfate ABC transporter"^^xsd:string) AnnotationAssertion( "sulfate transporting ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfate transmembrane-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "sulfate/thiosulfate porter activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.25"^^xsd:string) "sulfate-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "sulphate transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.25"^^xsd:string) "ATP phosphohydrolase (sulfate-importing) activity"^^xsd:string) AnnotationAssertion( "sulphate-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.25"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sulfate(out) = ADP + phosphate + sulfate(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cobalamin porter activity"^^xsd:string) AnnotationAssertion( "vitamin B12 porter activity"^^xsd:string) AnnotationAssertion( "cobalamin ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.33"^^xsd:string) "Catalysis of the reaction: ATP + H2O + cob(III)alamin(out) = ADP + phosphate + cob(III)alamin(in). Cobalamin is also known as vitamin B12."^^xsd:string) AnnotationAssertion( "vitamin B12-transporting ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cobalamin-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.33"^^xsd:string) "ATP phosphohydrolase (vitamin B12-importing)"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oligopeptide-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "oligopeptide ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.23"^^xsd:string) "ATP phosphohydrolase (oligopeptide-importing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.23"^^xsd:string) "oligopeptide permease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.23"^^xsd:string) "Catalysis of the reaction: ATP + H2O + oligopeptide(out) = ADP + phosphate + oligopeptide(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.18"^^xsd:string) "ATP phosphohydrolase (disaccharide-importing)"^^xsd:string) AnnotationAssertion(rdfs:label "oligosaccharide-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.18"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligosaccharide(out) = ADP + phosphate + oligosaccharide(in)."^^xsd:string) AnnotationAssertion( "oligosaccharide ABC transporter"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "maltose-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "maltose ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.19"^^xsd:string) "ATP phosphohydrolase (maltose-importing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.19"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + maltose(out) = ADP + phosphate + maltose(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out/in) = ADP + phosphate + amino acid(in/out)."^^xsd:string) AnnotationAssertion( "amino acid ABC transporter"^^xsd:string) AnnotationAssertion(rdfs:label "amino acid-transporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "leucine/isoleucine/valine porter activity"^^xsd:string) AnnotationAssertion( "nonpolar-amino acid ABC transporter"^^xsd:string) AnnotationAssertion( "nonpolar-amino-acid-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "nonpolar amino acid-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.22"^^xsd:string) "ATP phosphohydrolase (nonpolar-amino-acid-transporting) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.22"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in)."^^xsd:string) AnnotationAssertion(rdfs:label "nonpolar-amino acid-transporting ATPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "histidine/arginine/lysine/ornithine porter activity"^^xsd:string) AnnotationAssertion( "cystine/diaminopimelate porter activity"^^xsd:string) AnnotationAssertion( "polar amino acid-importing ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.21"^^xsd:string) "polar-amino-acid-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.21"^^xsd:string) "histidine permease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.21"^^xsd:string) "ATP phosphohydrolase (polar-amino-acid-importing) activity"^^xsd:string) AnnotationAssertion( "glutamate/aspartate porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "polar-amino acid-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "polar-amino acid ABC transporter"^^xsd:string) AnnotationAssertion( "polar amino acid uptake transporter activity"^^xsd:string) AnnotationAssertion( "polar-amino acid-importing ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.21"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycerol-3-phosphate-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.20"^^xsd:string) "ATP phosphohydrolase (glycerol-3-phosphate-importing)"^^xsd:string) AnnotationAssertion( "glycerol-3-phosphate ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.20"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-3-phosphate(out) = ADP + phosphate + glycerol-3-phosphate(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ATP-dependent glutathione S-conjugate export pump"^^xsd:string) AnnotationAssertion( "conjugate transporter activity"^^xsd:string) AnnotationAssertion( "MRP1/GS-X pump"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:1455517"^^xsd:string) "Catalysis of the reaction: ATP + H2O + glutathione S-conjugate(in) -> ADP + phosphate + glutathione S-conjugate(out)."^^xsd:string) AnnotationAssertion(rdfs:label "glutathione S-conjugate-exporting ATPase activity"^^xsd:string) AnnotationAssertion( "GS-X pump"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:3.A.1.207.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(in) + ATP + H2O -> bile acid(out) + ADP + phosphate."^^xsd:string) AnnotationAssertion( "bile acid porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "bile acid-exporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "major histocompatibility peptide transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:3.A.1.209.1"^^xsd:string) "Catalysis of the reaction: peptide antigen(in) + ATP = peptide antigen(out) + ADP + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "peptide antigen-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "peptide antigen transporter activity"^^xsd:string) AnnotationAssertion( "peptide antigen ABC transporter"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.46"^^xsd:string) "ATP phosphohydrolase (heavy-metal-exporting)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.46"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd (cytosol) = ADP + phosphate + Cd (vacuole)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.46"^^xsd:string) "yeast cadmium factor"^^xsd:string) AnnotationAssertion( "cadmium ABC transporter"^^xsd:string) AnnotationAssertion(rdfs:label "cadmium-transporting ATPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "capsular-polysaccharide-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.38"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + capsular polysaccharide(in) = ADP + phosphate + capsular polysaccharide(out)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.38"^^xsd:string) "ATP phosphohydrolase (capsular-polysaccharide-exporting)"^^xsd:string) AnnotationAssertion( "capsular-polysaccharide ABC transporter"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "LPS-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.39"^^xsd:string) "ATP phosphohydrolase (lipopolysaccharide-exporting)"^^xsd:string) AnnotationAssertion( "lipopolysaccharide ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.39"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipopolysaccharide(in) = ADP + phosphate + lipopolysaccharide(out)."^^xsd:string) AnnotationAssertion(rdfs:label "lipopolysaccharide-transporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.40"^^xsd:string) "ATP phosphohydrolase (teichoic-acid-exporting)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.40"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + teichoic acid(in) = ADP + phosphate + teichoic acid(out)."^^xsd:string) AnnotationAssertion(rdfs:label "teichoic-acid-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "teichoic-acid ABC transporter"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "heme ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.41"^^xsd:string) "Catalysis of the reaction: ATP + H2O + heme(in) = ADP + phosphate + heme(out)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.41"^^xsd:string) "ATP phosphohydrolase (heme-exporting)"^^xsd:string) AnnotationAssertion( "haem-transporting ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "heme-transporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.43"^^xsd:string) "ATP phosphohydrolase (peptide-exporting)"^^xsd:string) AnnotationAssertion( "peptide ABC transporter"^^xsd:string) AnnotationAssertion(rdfs:label "peptide-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.43"^^xsd:string) "Catalysis of the reaction: ATP + H2O + peptide(in) = ADP + phosphate + peptide(out). Peptides exported include alpha-hemolysin, cyclolysin, colicin V and siderophores from Gram-negative bacteria, and bacteriocin, subtilin, competence factor and pediocin from Gram-positive bacteria."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.42"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + beta-glucan(in) = ADP + phosphate + beta-glucan(out)."^^xsd:string) AnnotationAssertion( "beta-glucan ABC transporter"^^xsd:string) AnnotationAssertion(rdfs:label "beta-glucan-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.42"^^xsd:string) "ATP phosphohydrolase (beta-glucan-exporting)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mg2+(out) -> ADP + phosphate + Mg2+(in)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.2"^^xsd:string) "ATP phosphohydrolase (Mg2+-importing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.2"^^xsd:string) "magnesium-translocating P-type ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "magnesium-importing ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.2"^^xsd:string) "Mg(2+)-importing ATPase activity"^^xsd:string) AnnotationAssertion( "magnesium importing ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.2"^^xsd:string) "Mg2+-importing ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.53"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ag+(in) -> ADP + phosphate + Ag+(out)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.53"^^xsd:string) "Ag+-exporting ATPase activity"^^xsd:string) AnnotationAssertion( "silver exporting ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "silver-exporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.53"^^xsd:string) "ATP phosphohydrolase (Ag+-exporting)"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "arsenite transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.16"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arsenite(in) = ADP + phosphate + arsenite(out)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.16"^^xsd:string) "arsenite-translocating ATPase activity"^^xsd:string) AnnotationAssertion( "arsenical resistance efflux pump"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.16"^^xsd:string) "arsenical pump-driving ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.16"^^xsd:string) "ATP phosphohydrolase (arsenite-exporting) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.16"^^xsd:string) "arsenical resistance ATPase activity"^^xsd:string) AnnotationAssertion( "arsenite ABC transporter"^^xsd:string) AnnotationAssertion(rdfs:label "arsenite-transmembrane transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.16"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "arsenite-transporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "protein translocase activity"^^xsd:string) AnnotationAssertion(rdfs:label "P-P-bond-hydrolysis-driven protein transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Decarboxylation-driven transporters"^^xsd:string) AnnotationAssertion(rdfs:label "decarboxylation-driven active transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:3.B.-.-.-"^^xsd:string) "Primary active transport of a solute across a membrane driven by decarboxylation of a cytoplasmic substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:3.C.-.-.-"^^xsd:string) "Primary active transport of a solute across a membrane driven by a methyl transfer reaction. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source."^^xsd:string) AnnotationAssertion(rdfs:label "methyl transfer-driven active transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "Methyltransfer-driven transporters"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:3.D.-.-.-"^^xsd:string) "Primary active transport of a solute across a membrane, driven by exothermic flow of electrons from a reduced substrate to an oxidized substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source."^^xsd:string) AnnotationAssertion( "Oxidoreduction-driven transporters"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreduction-driven active transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "light-driven active transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:3.E.-.-.-"^^xsd:string) "Primary active transport of a solute across a membrane, driven by light. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source."^^xsd:string) AnnotationAssertion( "Light absorption-driven transporters"^^xsd:string) AnnotationAssertion( "light-driven pumps"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "potassium channel regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Modulates the activity of a potassium channel."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "protein-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "pilin/fimbrilin exporter activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein(out) = ADP + phosphate + protein(in)."^^xsd:string) AnnotationAssertion(rdfs:label "protein-transmembrane transporting ATPase activity"^^xsd:string) AnnotationAssertion( "protein ABC transporter"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with acetylcholine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "acetylcholine receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "G protein enhanced inward rectifier potassium channel activity"^^xsd:string) AnnotationAssertion(rdfs:label "G-protein activated inward rectifier potassium channel activity"^^xsd:string) AnnotationAssertion( "G-protein-enhanced inward rectifier potassium channel activity"^^xsd:string) AnnotationAssertion( "G-protein-activated inward rectifier potassium channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by a G protein. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force."^^xsd:string) AnnotationAssertion( "G-protein enhanced inward rectifier potassium channel activity"^^xsd:string) AnnotationAssertion( "G protein activated inward rectifier potassium channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Enables the energy independent passage of nucleoside, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria."^^xsd:string) AnnotationAssertion(rdfs:label "nucleoside-specific channel forming porin activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:1.B.11.-.-"^^xsd:string) "A porin that acts in the assembly of fimbria together with fimbrial chaperone."^^xsd:string) AnnotationAssertion(rdfs:label "fimbrial usher porin activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "autotransporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:1.B.12.-.-"^^xsd:string) "Transports a passenger protein from the periplasm to the external milieu; the passenger protein and the porin are the N- and C-terminal regions of the same protein, respectively."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of adhesin from the periplasm to the external milieu; the adhesin and the porin are the N- and C-terminal regions of the same protein, respectively."^^xsd:string) AnnotationAssertion(rdfs:label "adhesin autotransporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hemaglutinin autotransporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of hemaglutinin from the periplasm to the external milieu; the hemaglutinin and the porin are the N- and C-terminal regions of the same protein, respectively."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of oligosaccharide, sized less than 1000 Da, from one side of the membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria."^^xsd:string) AnnotationAssertion( "raffinose porin"^^xsd:string) AnnotationAssertion(rdfs:label "oligosaccharide transporting porin activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "maltose transporting porin activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of maltose from one side of the membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch. This transporter is a porin so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria."^^xsd:string) AnnotationAssertion( "maltoporin"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "long-chain fatty acid transporting porin activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15904"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of long-chain fatty acids from one side of the membrane to the other. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. This transporter is a porin and so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."^^xsd:string) AnnotationAssertion(rdfs:label "cholesterol binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.2.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (glycoside, pentoside or hexuronide)(out) + monovalent cation(out) = (glycoside, pentoside or hexuronide)(in) + monovalent cation(in). The cation is Na+, Li+ or H+."^^xsd:string) AnnotationAssertion(rdfs:label "glycoside-pentoside-hexuronide:cation symporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "melibiose:monovalent cation symporter activity"^^xsd:string) AnnotationAssertion( "melibiose permease activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.2.1.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + monovalent cation(out) = melibiose(in) + monovalent cation(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.2.3.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucuronide(out) + monovalent cation(out) = glucuronide(in) + monovalent cation(in)."^^xsd:string) AnnotationAssertion( "glucuronoside permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucuronide:monovalent cation symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of putrescine from one side of the membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine."^^xsd:string) AnnotationAssertion(rdfs:label "putrescine transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of cadaverine, 1,5-pentanediamine, from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "cadaverine transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation A(out) + cation B(in) = cation A(in) + cation B(out)."^^xsd:string) AnnotationAssertion(rdfs:label "cation:cation antiporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phenylalanine:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.3.1.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phenylalanine(out) + H+(out) = phenylalanine(in) + H+(in)."^^xsd:string) AnnotationAssertion( "phenylalanine:proton symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "lysine:proton symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.3.1.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lysine(out) + H+(out) = lysine(in) + H+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "lysine:hydrogen symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "aromatic amino acid:proton symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "aromatic amino acid:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.3.1.3"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: aromatic amino acid(out) + H+(out) = aromatic amino acid(in) + H+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.18.5.1"^^xsd:string) Annotation( "TC:2.A.3.1.4"^^xsd:string) Annotation( "TC:2.A.3.4.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + H+(out) = gamma-aminobutyric acid(in) + H+(in)."^^xsd:string) AnnotationAssertion( "4-aminobutyrate:proton symporter activity"^^xsd:string) AnnotationAssertion( "4-aminobutanoate:proton symporter activity"^^xsd:string) AnnotationAssertion( "4-aminobutanoate:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "4-aminobutyrate:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "GABA:proton symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "gamma-aminobutyric acid:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "GABA:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "gamma-aminobutyric acid:proton symporter activity"^^xsd:string) AnnotationAssertion( "gamma-aminobutyric acid permease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "putrescine:ornithine antiporter activity"^^xsd:string) AnnotationAssertion( "putrescine:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "putrescine-ornithine antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.3.2.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: putrescine(out) + ornithine(in) = putrescine(in) + ornithine(out)."^^xsd:string) AnnotationAssertion( "putrescine/ornithine antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.21.1.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: pantothenate(out) + Na+(out) = pantothenate(in) + Na+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "pantothenate:sodium symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "formate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of formate from one side of the membrane to the other. Formate is also known as methanoate, the anion HCOO- derived from methanoic (formic) acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sodium/excitatory glutamate cotransporter activity"^^xsd:string) AnnotationAssertion( "sodium/excitatory glutamate symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.27.1.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + Na+(out) = glutamate(in) + Na+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "glutamate:sodium symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutathione-regulated potassium exporter activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11053405"^^xsd:string) Annotation( "TC:2.A.37.1.1"^^xsd:string) Annotation( "TC:2.A.37.1.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cytosine permease activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.39.1.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cytosine(out) + H+(out) = cytosine(in) + H+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "cytosine:hydrogen ion symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uracil(out) + cation(out) = uracil(in) + cation(in)."^^xsd:string) AnnotationAssertion( "uracil permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "uracil:cation symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.1.10.1"^^xsd:string) Annotation( "TC:2.A.41.1.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + H+(out) = nucleoside(in) + H+(in)."^^xsd:string) AnnotationAssertion( "nucleoside:hydrogen ion symporter activity"^^xsd:string) AnnotationAssertion( "nucleoside:proton symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "nucleoside:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "nucleoside permease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "nitrite uptake permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "nitrite uptake transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of nitrite from the outside of a cell to the inside of the cell across a membrane."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nitrite efflux transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "nitrite extrusion permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of nitrite from the inside of the cell to the outside of the cell across a membrane."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "citrate:succinate antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.47.3.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + succinate(in) = citrate(in) + succinate(out)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.47.3.3"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: tartrate(out) + succinate(in) = tartrate(in) + succinate(out)."^^xsd:string) AnnotationAssertion(rdfs:label "tartrate:succinate antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.1.1.1"^^xsd:string) Annotation( "TC:2.A.1.1.9"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + H+(out) = galactose(in) + H+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "galactose:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "galactose:proton symporter activity"^^xsd:string) AnnotationAssertion( "lactose, galactose:hydrogen symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "arabinose:proton symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.1.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: arabinose(out) + H+(out) = arabinose(in) + H+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "arabinose:hydrogen symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-xylose:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.1.3"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-xylose(out) + H+(out) = D-xylose(in) + H+(in)."^^xsd:string) AnnotationAssertion( "D-xylose:proton symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "tetracyclin:proton antiporter activity"^^xsd:string) AnnotationAssertion( "tetracyclin:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.2.4"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + tetracycline(in) = H+(in) + tetracycline(out)."^^xsd:string) AnnotationAssertion(rdfs:label "tetracycline:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion( "tetracycline:proton antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydrophobic uncoupler:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion( "hydrophobic uncoupler:proton antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.2.9"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hydrophobic uncoupler(in) + H+(out) = hydrophobic uncoupler(out) + H+(in). Hydrophobic uncouplers include CCCP, benzalkonium and SDS."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arabinose efflux transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "arabinose efflux permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:2.A.1.2.14"^^xsd:string) "Catalysis of the transfer of arabinose from the inside of the cell to the outside of the cell across a membrane: H+(out) + arabinose(in) = H+(in) + arabinose(out)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.1.4.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose phosphate(out) + inorganic phosphate(in) = hexose phosphate(in) + inorganic phosphate(out)."^^xsd:string) AnnotationAssertion(rdfs:label "hexose-phosphate:inorganic phosphate antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycerol-phosphate:inorganic phosphate antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.4.3"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerol phosphate(out) + inorganic phosphate(in) = glycerol phosphate(in) + inorganic phosphate(out)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.1.1.9"^^xsd:string) Annotation( "TC:2.A.1.5.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactose(out) + H+(out) = lactose(in) + H+(in)."^^xsd:string) AnnotationAssertion( "lactose, galactose:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "lactose:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "lactose:proton symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "raffinose:proton symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "raffinose:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.5.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: raffinose(out) + H+(out) = raffinose(in) + H+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "shikimate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of shikimate from one side of the membrane to the other. Shikimate is an important intermediate in the biosynthesis of aromatic amino acids."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "citrate:proton symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.6.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + H+(out) = citrate(in) + H+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "citrate:hydrogen symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2-oxoglutarate:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.6.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-ketoglutarate(out) + H+(out) = alpha-ketoglutarate(in) + H+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-ketoglutarate:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "alpha-ketoglutarate:proton symporter activity"^^xsd:string) AnnotationAssertion( "2-oxoglutarate:proton symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "shikimate:proton symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "shikimate:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.6.6"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: shikimate(out) + H+(out) = shikimate(in) + H+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "fucose:proton symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "fucose:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.7.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fucose(out) + H+(out) = fucose(in) + H+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "xanthosine permease activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.10.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: xanthosine(out) + H+(out) = xanthosine(in) + H+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "xanthosine:hydrogen ion symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.1.12.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + H+(out) = sialate(in) + H+(in)."^^xsd:string) AnnotationAssertion( "sialic acid permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "sialic acid:hydrogen symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "hexuronate (glucuronate/galacturonate) porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "hexuronate:cation symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.14.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexuronate(out) + cation(out) = hexuronate(in) + cation(in). The hexuronate may be glucuronate or galacturonate."^^xsd:string) AnnotationAssertion( "hexuronate porter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3-hydroxyphenyl propionate porter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.15.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 3-hydroxyphenyl propionate(out) + H+(out) = 3-hydroxyphenyl propionate(in) + H+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxyphenyl propionate:hydrogen ion symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cyanate porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "secondary active cyanate uptake transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.1.17.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cyanate(out) = cyanate(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:2.A.1.20.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(in) = sugar(out)."^^xsd:string) AnnotationAssertion(rdfs:label "sugar efflux transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "lactose/glucose efflux transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "TC:2.A.1.27.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phenyl propionate(out) = phenyl propionate(in)."^^xsd:string) AnnotationAssertion(rdfs:label "phenyl propionate uptake uniporter activity"^^xsd:string) AnnotationAssertion( "phenyl propionate permease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bicyclomycin transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:91191028X"^^xsd:string) "Enables the directed movement of bicyclomycin into, out of or within a cell, or between cells. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive."^^xsd:string) AnnotationAssertion( "bicyclomycin/sulfathiazole:hydrogen antiporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sulphathiazole transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfathiazole transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "bicyclomycin/sulfathiazole:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:9337"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Enables the directed movement of sulfathiazole across a membrane. Sulfathiazole is an antibacterial agent of the sulfonamide group."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nalidixic acid transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) Annotation( "PMID:12702699"^^xsd:string) Annotation( "PubChem_Compound:4221"^^xsd:string) "Enables the directed movement of nalidixic acid into, out of or within a cell, or between cells. Nalidixic acid is a synthetic antibiotic that interferes with DNA gyrase and inhibits prokaryotic replication."^^xsd:string) AnnotationAssertion( "carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "organomercurial transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of organomercurial compounds into, out of or within a cell, or between cells. Organomercurial substances are any organic compound containing a mercury atom."^^xsd:string) AnnotationAssertion( "carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:3259"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Enables the directed movement of carbonyl cyanide m-chlorophenylhydrazone into, out of or within a cell, or between cells. Carbonyl cyanide m-chlorophenylhydrazone is a proton ionophore, commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes."^^xsd:string) AnnotationAssertion( "carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "carbonyl cyanide m-chlorophenylhydrazone transporter activity"^^xsd:string) AnnotationAssertion( "CCCP transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of galacturonate from one side of the membrane to the other. Galacturonate is the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group."^^xsd:string) AnnotationAssertion(rdfs:label "galacturonate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3-hydroxyphenyl propionate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxyphenyl propanoate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of 3-hydroxyphenyl propanoate from one side of the membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of propionate from one side of the membrane to the other. Propionate (or propanoate) is the organic acid CH3-CH2-COOH."^^xsd:string) AnnotationAssertion(rdfs:label "propionate transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "xanthosine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of xanthosine, xanthine riboside, from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tartrate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of tartrate from one side of the membrane to the other. Tartrate is the anion of 2,3-dihydroxybutanedioic acid, one of the aldaric acids. The L(+) enantiomer occurs widely in plants, especially in grape juice, and in fungi and bacteria."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Catalysis of the transfer of C4-dicarboxylate from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "C4-dicarboxylate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arginine targeting transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) Annotation( "PMID:17956229"^^xsd:string) "Enables the directed movement of fully folded proteins into, out of or within a cell, or between cells, by targeting the proteins to the transporter via a specialized N-terminal twin arginine signal peptide."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "p-aminobenzoyl-glutamate uptake permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of p-aminobenzoyl-glutamate from the outside of a cell to the inside of the cell across a membrane."^^xsd:string) AnnotationAssertion(rdfs:label "p-aminobenzoyl-glutamate uptake transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:2.A.7.6.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: rhamnose(out) + H+(out) = rhamnose(in) + H+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "rhamnose:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "rhamnose:proton symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane."^^xsd:string) AnnotationAssertion( "monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity"^^xsd:string) AnnotationAssertion( "efflux permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "efflux transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "uptake transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "uptake permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a specific substance or related group of substances from the outside of a cell to the inside across a membrane."^^xsd:string) AnnotationAssertion( "zinc, iron permease activity"^^xsd:string) AnnotationAssertion( "cobalt, zinc uptake permease activity"^^xsd:string) AnnotationAssertion( "monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity"^^xsd:string) AnnotationAssertion( "zinc, cadmium uptake permease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "threonine efflux transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "threonine export transporter activity"^^xsd:string) AnnotationAssertion( "threonine efflux permease activity"^^xsd:string) AnnotationAssertion( "threonine export protein"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of threonine from the inside of the cell to the outside of the cell across a membrane."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "acriflavin transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "acriflavine transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "acriflavin resistant pump activity"^^xsd:string) AnnotationAssertion(Annotation( "PubChem_Compound:6842"^^xsd:string) "Enables the directed movement of acriflavin into, out of or within a cell, or between cells. Acriflavin is a fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of alkanes into, out of or within a cell, or between cells. Alkanes are saturated aliphatic hydrocarbon compounds."^^xsd:string) AnnotationAssertion(rdfs:label "alkane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-idonate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "L-idonate/D-gluconate:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of L-idonate from one side of the membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of p-aminobenzoyl-glutamate from one side of a membrane to the other. p-aminobenzoyl-glutamate is the anion of p-aminobenzoyl-glutamic acid."^^xsd:string) AnnotationAssertion(rdfs:label "p-aminobenzoyl-glutamate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "p-aminobenzoyl-glutamate transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "N-acetylgalactosamine permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of N-acetylgalactosamine from one side of the membrane to the other. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine."^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylgalactosamine transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of N-acetylglucosamine from one side of the membrane to the other. The D isomer of N-acetylglucosamine is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein."^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylglucosamine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "N-Acetyl-D-glucosamine permease"^^xsd:string) AnnotationAssertion( "N-acetylglucosamine permease activity"^^xsd:string) AnnotationAssertion( "N-acetyl-D-glucosamine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "N-acetylchitosamine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "D-GlcNAc transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "beta-glucoside permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-glucoside transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "http://www.biochem.purdue.edu/"^^xsd:string) "Catalysis of the transfer of beta-glucosides from one side of the membrane to the other. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "trehalose permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "trehalose transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of trehalose from one side of the membrane to the other. Trehalose is the disaccharide alpha-D-glucopyranosyl-alpha-D-glucopyranoside that acts of a reserve carbohydrate in certain fungi, algae and lichens."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mannitol transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "mannitol permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of mannitol from one side of the membrane to the other. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glucitol transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of sorbitol from one side of the membrane to the other. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose."^^xsd:string) AnnotationAssertion( "sorbitol permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "sorbitol transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "glucitol permease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "galactitol permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactitol transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a galactitol from one side of the membrane to the other. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mannose transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "mannose permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of mannose from one side of the membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of D-ribose from one side of the membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12."^^xsd:string) AnnotationAssertion(rdfs:label "D-ribose transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methylgalactoside transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:55507"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of methylgalactoside from one side of the membrane to the other. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group."^^xsd:string) AnnotationAssertion( "galactose/glucose (methylgalactoside) porter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "allose transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of allose from one side of the membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.31"^^xsd:string) "Catalysis of the reaction: ATP + H2O + putrescine(out) -> ADP + phosphate + putrescine(in)."^^xsd:string) AnnotationAssertion(rdfs:label "putrescine-importing ATPase activity"^^xsd:string) AnnotationAssertion( "putrescine porter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "spermidine porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "spermidine-importing ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.31"^^xsd:string) "Catalysis of the reaction: ATP + H2O + spermidine(out) -> ADP + phosphate + spermidine(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arginine-importing ATPase activity"^^xsd:string) AnnotationAssertion( "arginine porter activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.21"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arginine(out) -> ADP + phosphate + arginine(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutamine-importing ATPase activity"^^xsd:string) AnnotationAssertion( "glutamine porter activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.21"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glutamine(out) -> ADP + phosphate + glutamine(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "iron chelate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "http://www.onelook.com"^^xsd:string) "Catalysis of the transfer of an iron chelate from one side of a membrane to the other. An iron chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "organic phosphonate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of phosphonate from one side of a membrane to the other. A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "organophosphate ester transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mcc"^^xsd:string) "Catalysis of the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "spermidine transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of a fatty acyl CoA group into, out of or within a cell, or between cells. A fatty acyl CoA group is any acyl group derived from a fatty acid with a coenzyme A group attached to it."^^xsd:string) AnnotationAssertion(rdfs:label "fatty-acyl-CoA transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "fatty acyl CoA transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sugar transporter"^^xsd:string) AnnotationAssertion( "carbohydrate uptake transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "carbohydrate-importing ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "TC:3.A.1.1.-"^^xsd:string) Annotation( "TC:3.A.1.2.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(out) -> ADP + phosphate + carbohydrate(in)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "maltooligosaccharide-importing ATPase activity"^^xsd:string) AnnotationAssertion( "maltooligosaccharide porter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:3.A.1.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + maltooligosaccharide(out) -> ADP + phosphate + maltooligosaccharide(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycerol phosphate-importing ATPase activity"^^xsd:string) AnnotationAssertion( "glycerol-phosphate porter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:3.A.1.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-phosphate(out) -> ADP + phosphate + glycerol-phosphate(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "D-ribose porter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:3.A.1.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-ribose(out) -> ADP + phosphate + D-ribose(in)."^^xsd:string) AnnotationAssertion(rdfs:label "D-ribose-importing ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:3.A.1.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-arabinose(out) -> ADP + phosphate + L-arabinose(in)."^^xsd:string) AnnotationAssertion( "L-arabinose porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-arabinose-importing ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "D-xylose porter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:3.A.1.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-xylose(out) -> ADP + phosphate + D-xylose(in)."^^xsd:string) AnnotationAssertion(rdfs:label "D-xylose-importing ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:3.A.1.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-allose(out) -> ADP + phosphate + D-allose(in)."^^xsd:string) AnnotationAssertion( "D-allose porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-allose-importing ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:16428451"^^xsd:string) Annotation( "PMID:17631491"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded DNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "DNA translocase activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "TC:3.A.1.19.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiamine pyrophosphate(out) = ADP + phosphate + thiamine pyrophosphate(in)."^^xsd:string) AnnotationAssertion( "thiamin pyrophosphate porter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "thiamin pyrophosphate transporting ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiamine pyrophosphate-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "TPP transporting ATPase activity"^^xsd:string) AnnotationAssertion( "thiamin pyrophosphate ABC transporter"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ferric-enterobactin transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of ferric-enterobactin from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ferric triacetylfusarinine C transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of ferric triacetylfusarinine C from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of ferric-hydroxamate from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "ferric-hydroxamate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ferric/ferric-dicitrate porter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.34"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + iron chelate(out) = ADP + phosphate + iron chelate(in). Fe-enterobactin, Fe-dicitrate, Fe-hydroxamate and other siderophores are imported."^^xsd:string) AnnotationAssertion( "iron-chelate ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.34"^^xsd:string) "ATP phosphohydrolase (iron-chelate-importing)"^^xsd:string) AnnotationAssertion(rdfs:label "iron-chelate-transporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ferric-enterobactin-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "ferric-enterobactin ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "TC:3.A.1.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-enterobactin(out) = ADP + phosphate + ferric-enterobactin(in)."^^xsd:string) AnnotationAssertion( "ferric-enterobactin porter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ferric-hydroxamate porter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:3.A.1.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-hydroxamate(out) = ADP + phosphate + ferric-hydroxamate(in)."^^xsd:string) AnnotationAssertion(rdfs:label "ferric-hydroxamate-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "ferric-hydroxamate ABC transporter"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "GOC:jsg"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-diaminopimelate from one side of a membrane to the other. L-diaminopimelate is the L-enantiomer anion of 2,6-diaminoheptanedioic acid."^^xsd:string) AnnotationAssertion( "cystine/diaminopimelate porter activity"^^xsd:string) AnnotationAssertion( "L-diaminopimelate transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-diaminopimelate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:clt"^^xsd:string) "Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules."^^xsd:string) AnnotationAssertion(rdfs:label "tubulin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:3.A.1.-.-"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(out) = ADP + phosphate + Zn2+(in)."^^xsd:string) AnnotationAssertion( "zinc porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "zinc transporting ATPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "LPS exporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "lipopolysaccharide exporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of lipopolysaccharide from the inside of the cell to the outside of the cell across a membrane. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "short-chain fatty acid transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:26666"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of short-chain fatty acids into, out of or within a cell, or between cells. Short-chain fatty acids are fatty acids with a chain length of less than C6."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "short-chain fatty acid uptake transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:26666"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Enables the directed movement of short-chain fatty acids into a cell or organelle. Short-chain fatty acids are fatty acids with a chain length of less than C6."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "microcin uptake permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "microcin uptake transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a microcin from the outside of a cell to the inside of the cell across a membrane."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "TC:9.A.8.1.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Fe2+(out) + energy = Fe2+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "ferrous iron uptake transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "murein peptide transporter activity"^^xsd:string) AnnotationAssertion( "muropeptide transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of peptidoglycan peptides into, out of or within a cell, or between cells. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains."^^xsd:string) AnnotationAssertion(rdfs:label "peptidoglycan peptide transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "toxic substance binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) "Interacting selectively and non-covalently with a toxic substance, a poisonous substance that causes damage to biological systems."^^xsd:string) AnnotationAssertion( "lipoprotein antitoxin"^^xsd:string) AnnotationAssertion( "antitoxin activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "fatty acid CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "acyl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "fatty acid ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "fatty acyl-coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.20"^^xsd:string) Annotation( "EC:6.2.1.3"^^xsd:string) Annotation( "GOC:cjk"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP."^^xsd:string) AnnotationAssertion( "fatty-acid ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "acid:CoA ligase (AMP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.3"^^xsd:string) "acyl-coenzyme A ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion( "murein transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "peptidoglycan transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lipid-linked peptidoglycan transporter activity"^^xsd:string) AnnotationAssertion( "lipid-linked murein transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Enables the directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2-keto-3-deoxygluconate:proton symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-keto-3-deoxygluconate:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.10.1.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 2-keto-3-deoxygluconate(out) + H+(out) = 2-keto-3-deoxygluconate(in) + H+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "lactate permease"^^xsd:string) AnnotationAssertion( "lactate:hydrogen porter activity"^^xsd:string) AnnotationAssertion( "lactate:proton porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "lactate:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.14.1.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactate (out) + H+ (out) = lactate (in) + H+ (in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups."^^xsd:string) AnnotationAssertion( "quaternary amine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "quaternary ammonium compound transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "quaternary ammonium group transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: quaternary ammonium group(out) + H+(out) = quaternary ammonium group(in) + H+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "quaternary ammonium group:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "quaternary ammonium group:proton symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycine betaine:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "glycine betaine:proton symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.15.1.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine betaine(out) + H+(out) = glycine betaine(in) + H+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:2.A.16.1.1"^^xsd:string) "Catalysis of the transfer of tellurite from the outside of a cell to the inside across a membrane: tellurite(out) + H+(out) = tellurite(in) + H+(in)."^^xsd:string) AnnotationAssertion( "tellurite-resistance uptake transmembrane transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "tellurite uptake transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "tellurite-resistance uptake permease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alanine:sodium symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alanine(out) + Na+(out) = alanine(in) + Na+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "branched-chain amino acid:sodium symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "TC:2.A.26.1.1"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: branched-chain amino acid(out) + cation(out) = branched-chain amino acid(in) + cation(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "branched-chain amino acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:22918"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of branched-chain amino acids from one side of a membrane to the other. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings."^^xsd:string) AnnotationAssertion( "valine/tyrosine/tryptophan permease activity"^^xsd:string) AnnotationAssertion( "leucine/valine/isoleucine permease activity"^^xsd:string) AnnotationAssertion( "branched-chain aliphatic amino acid transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "branched-chain aliphatic amino acid transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "formate uptake permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "formate uptake transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of formate from the outside of a cell to the inside of the cell across a membrane."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of formate from the inside of the cell to the outside of the cell across a membrane."^^xsd:string) AnnotationAssertion( "formate efflux permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "formate efflux transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-lysine exporter activity"^^xsd:string) AnnotationAssertion( "L-lysine, 2,6-diaminohexanoic acid efflux transmembrane transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-lysine efflux transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of L-lysine from the inside of the cell to the outside of the cell across a membrane."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10322420"^^xsd:string) Annotation( "PMID:10600683"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate."^^xsd:string) AnnotationAssertion(rdfs:label "ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism"^^xsd:string) AnnotationAssertion( "zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity"^^xsd:string) AnnotationAssertion( "P-type ATPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nicotinamide mononucleotide transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "nicotinamide mononucleotide permease activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:50383"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) Annotation( "ISBN:0721662544"^^xsd:string) "Enables the directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP."^^xsd:string) AnnotationAssertion( "nicotinamide ribonucleotide transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alcohol transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of an alcohol from one side of the membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "restriction enzyme activity"^^xsd:string) AnnotationAssertion( "restriction endonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks."^^xsd:string) AnnotationAssertion(rdfs:label "restriction endodeoxyribonuclease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.113"^^xsd:string) "modification methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.113"^^xsd:string) "S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.113"^^xsd:string) "N4-cytosine-specific DNA methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.113"^^xsd:string) "N(4)-cytosine-specific DNA methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.113"^^xsd:string) "m4C-forming MTase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.113"^^xsd:string) "S-adenosyl-L-methionine:DNA-cytosine N4-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.113"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.113"^^xsd:string) "DNA[cytosine-N4]methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "site-specific DNA-methyltransferase (cytosine-N4-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.113"^^xsd:string) "restriction-modification system activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Type III restriction enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.5"^^xsd:string) Annotation( "PMID:12654995"^^xsd:string) "Catalysis of the endonucleolytic cleavage of DNA to give double-stranded fragments with terminal 5'-phosphates. ATP hydrolysis is required. Cleavage is dependent on the presence of two copies of a specific recognition sequence in an inverse orientation in the DNA. Cleavage occurs at a specific distance from one of the recognition sites."^^xsd:string) AnnotationAssertion(rdfs:label "Type III site-specific deoxyribonuclease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aspartate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.1"^^xsd:string) Annotation( "EC:1.4.3.16"^^xsd:string) "Catalysis of the reaction: aspartate + O2 = iminosuccinate + hydrogen peroxide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative."^^xsd:string) AnnotationAssertion(rdfs:label "mannosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mannosyl-oligosaccharide mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.-"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of the terminal alpha-D-mannose residues in oligo-mannose oligosaccharides."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of galactosyl compounds, substances containing a group derived from a cyclic form of galactose or a galactose derivative."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the hydrolysis of glucosyl compounds, substances containing a group derived from a cyclic form of glucose or a glucose derivative."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of trehalose or a trehalose derivative."^^xsd:string) AnnotationAssertion(rdfs:label "trehalase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of fucosyl compounds, substances containing a group derived from a cyclic form of fucose or a fucose derivative."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hexosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0721662544"^^xsd:string) Annotation( "http://www.onelook.com/"^^xsd:string) "Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) residues from gangliosides or other glycoside oligosaccharides."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutamate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.-.-"^^xsd:string) "Catalysis of the formation of L-glutamine and 2-oxoglutarate from L-glutamate, using NADH, NADPH or ferredoxin as hydrogen acceptors."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "nucleobase-containing compound transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.99.1"^^xsd:string) "assimilatory sulfite reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.1"^^xsd:string) "Catalysis of the reaction: hydrogen sulfide + acceptor + 3 H2O = sulfite + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.1"^^xsd:string) "assimilatory-type sulfite reductase activity"^^xsd:string) AnnotationAssertion( "sulphite reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:SULFITE-REDUCTASE-RXN"^^xsd:string) "siroheme sulfite reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfite reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.1"^^xsd:string) "hydrogen-sulfide:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.1"^^xsd:string) "hydrogen-sulfide:(acceptor) oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phospholipase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Increases the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "phospholipase A2 activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Increases the activity of the enzyme phospholipase A2."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "morphogen activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Acts as a trigger for a pattern specification process when present at a specific concentration within a gradient."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mb"^^xsd:string) "Interacting selectively and non-covalently with cyclosporin A, a cyclic undecapeptide that contains several N-methylated and unusual amino acids."^^xsd:string) AnnotationAssertion( "cyclophilin"^^xsd:string) AnnotationAssertion(rdfs:label "cyclosporin A binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peptidoglycan receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14698226"^^xsd:string) "Combining with a peptidoglycan and transmitting the signal to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "peptidoglycan recognition activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.2.1.2"^^xsd:string) "maleylacetone cis-trans-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.2"^^xsd:string) "4-maleylacetoacetate cis-trans-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.2"^^xsd:string) "maleylacetone isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "maleylacetoacetate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.2"^^xsd:string) "maleylacetoacetic isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.2"^^xsd:string) "Catalysis of the reaction: 4-maleylacetoacetate = 4-fumarylacetoacetate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.1.14"^^xsd:string) Annotation( "RHEA:13756"^^xsd:string) "Catalysis of the reaction: 2 L-glutamate + NAD(+) = 2-oxoglutarate + L-glutamine + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.14"^^xsd:string) "L-glutamate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.14"^^xsd:string) "L-glutamate:NAD+ oxidoreductase (transaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.14"^^xsd:string) "glutamate (reduced nicotinamide adenine dinucleotide) synthase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.14"^^xsd:string) "NADH-glutamate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamate synthase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.14"^^xsd:string) "L-glutamate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.14"^^xsd:string) "L-glutamate synthase (NADH)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.14"^^xsd:string) "NADH: GOGAT"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.14"^^xsd:string) "NADH-dependent glutamate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.7.1"^^xsd:string) "Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + 2 oxidized ferredoxin + H2O = NH3 + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.7.1"^^xsd:string) "ferredoxin-dependent glutamate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.7.1"^^xsd:string) "L-glutamate:ferredoxin oxidoreductase (transaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.7.1"^^xsd:string) "ferredoxin-glutamate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.7.1"^^xsd:string) "glutamate synthase (ferredoxin-dependent)"^^xsd:string) AnnotationAssertion(rdfs:label "glutamate synthase (ferredoxin) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "myostimulatory hormone activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12204246"^^xsd:string) "The action characteristic of myostimulatory hormone, a peptide hormone that stimulates muscle contraction."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:8902848"^^xsd:string) "The action characteristic of myostimulatory hormone, a peptide hormone that inhibits muscle contraction."^^xsd:string) AnnotationAssertion(rdfs:label "myoinhibitory hormone activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "DOI:10.1002/(SICI)1520-6327(1997)35:1"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "The action characteristic of ecdysiostatic hormone, a peptide hormone that inhibits ecdysone secretion."^^xsd:string) AnnotationAssertion(rdfs:label "ecdysiostatic hormone activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198547684"^^xsd:string) "A translation release factor that is specific for one or more particular termination codons; acts at the ribosomal A-site and require polypeptidyl-tRNA at the P-site."^^xsd:string) AnnotationAssertion(rdfs:label "translation release factor activity, codon specific"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198547684"^^xsd:string) "A translation release factor that is not specific to particular codons; binds to guanine nucleotides."^^xsd:string) AnnotationAssertion(rdfs:label "translation release factor activity, codon nonspecific"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nickel cation binding"^^xsd:string) AnnotationAssertion( "nickel binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with nickel (Ni) cations."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.16.1.1"^^xsd:string) "Hg:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.1"^^xsd:string) Annotation( "RHEA:23859"^^xsd:string) "Catalysis of the reaction: H(+) + Hg + NADP(+) = Hg(2+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.1"^^xsd:string) "mercury(II) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.1"^^xsd:string) "mercurate(II) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.1"^^xsd:string) "mercuric reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.1"^^xsd:string) "mer A"^^xsd:string) AnnotationAssertion(rdfs:label "mercury (II) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.1"^^xsd:string) "mercuric ion reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.1"^^xsd:string) "reduced NADP:mercuric ion oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.1"^^xsd:string) "mercury reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.49"^^xsd:string) "urocanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.49"^^xsd:string) "3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate hydro-lyase (urocanate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.49"^^xsd:string) "3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.49"^^xsd:string) "imidazolonepropionate hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "urocanate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.49"^^xsd:string) Annotation( "RHEA:13104"^^xsd:string) "Catalysis of the reaction: 4-imidazolone-5-propanoate + H(+) = trans-urocanate + H(2)O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyrimidine-nucleoside phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.2"^^xsd:string) "pyrimidine-nucleoside:phosphate alpha-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.2"^^xsd:string) "Py-NPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.2"^^xsd:string) "Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.6"^^xsd:string) "10-formyltetrahydrofolate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "formyltetrahydrofolate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.6"^^xsd:string) "N10-formyltetrahydrofolate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.6"^^xsd:string) "10-formyl tetrahydrofolate:NADP oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.6"^^xsd:string) "10-formyltetrahydrofolate:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.6"^^xsd:string) "10-formyl-H2PtGlu:NADP oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.6"^^xsd:string) "10-formyl-H4folate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.6"^^xsd:string) Annotation( "RHEA:10183"^^xsd:string) "Catalysis of the reaction: 10-formyltetrahydrofolate + H(2)O + NADP(+) = (6S)-5,6,7,8-tetrahydrofolate + CO(2) + H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fumarate reductase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.6"^^xsd:string) "succinate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.6"^^xsd:string) "NADH-fumarate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.6"^^xsd:string) Annotation( "RHEA:18284"^^xsd:string) "Catalysis of the reaction: NAD(+) + succinate = fumarate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.6"^^xsd:string) "NADH-dependent fumarate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.13"^^xsd:string) "NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.13"^^xsd:string) "UDPglucose-fructose glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.13"^^xsd:string) "UDP-glucose-fructose glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.13"^^xsd:string) "uridine diphosphoglucose-fructose glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.13"^^xsd:string) "sucrose-UDP glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.13"^^xsd:string) "Catalysis of the reaction: UDP-glucose + D-fructose = UDP + sucrose."^^xsd:string) AnnotationAssertion(rdfs:label "sucrose synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.13"^^xsd:string) "sucrose-uridine diphosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.13"^^xsd:string) "sucrose synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phytate 3-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.8"^^xsd:string) "Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.8"^^xsd:string) "1-phytase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.8"^^xsd:string) "phytate 1-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.8"^^xsd:string) "myo-inositol-hexakisphosphate 3-phosphohydrolase activity"^^xsd:string) AnnotationAssertion( "myo-inositol-hexaphosphate 3-phosphohydrolase activity"^^xsd:string) AnnotationAssertion( "phytase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-phytase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "muconolactone delta-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.4"^^xsd:string) "muconolactone isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.4"^^xsd:string) "5-oxo-4,5-dihydrofuran-2-acetate delta3-delta2-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.4"^^xsd:string) "Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = 3,4-dihydro-5-oxofuran-2-acetate."^^xsd:string) AnnotationAssertion( "muconolactone D-isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of amylose or an amylose derivative."^^xsd:string) AnnotationAssertion(rdfs:label "amylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.2"^^xsd:string) "saccharogen amylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.2"^^xsd:string) "Catalysis of the reaction: (1,4-alpha-D-glucosyl)(n+1) + H2O = (1,4-alpha-D-glucosyl)(n-1) + alpha-maltose. This reaction is the hydrolysis of 1,4-alpha-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.2"^^xsd:string) "beta amylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-amylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.2"^^xsd:string) "1,4-alpha-D-glucan maltohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.2"^^xsd:string) "glycogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.91"^^xsd:string) "1,4-beta-cellobiohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.91"^^xsd:string) "1,4-beta-glucan cellobiosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.91"^^xsd:string) "cellobiohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.91"^^xsd:string) "1,4-beta-D-glucan cellobiohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cellulose 1,4-beta-cellobiosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.91"^^xsd:string) "C1 cellulase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.91"^^xsd:string) "exo-beta-1,4-glucan cellobiohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.91"^^xsd:string) "Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.91"^^xsd:string) "exocellobiohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.91"^^xsd:string) "beta-1,4-glucan cellobiohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.91"^^xsd:string) "exo-cellobiohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.91"^^xsd:string) "exoglucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.91"^^xsd:string) "avicelase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.91"^^xsd:string) "CBH 1"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.91"^^xsd:string) "cellobiohydrolase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.91"^^xsd:string) "cellobiosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.91"^^xsd:string) "beta-1,4-glucan cellobiosylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.91"^^xsd:string) "exo-1,4-beta-D-glucanase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "iron-iron nitrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nitrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.6.1"^^xsd:string) "Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + nitrogen + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.18.6.1"^^xsd:string) "reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing) activity"^^xsd:string) AnnotationAssertion( "vanadium-iron nitrogenase activity"^^xsd:string) AnnotationAssertion( "molybdenum-iron nitrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.12"^^xsd:string) "lionoleate:O2 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.12"^^xsd:string) "lipoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.12"^^xsd:string) "lipoperoxidase activity"^^xsd:string) AnnotationAssertion( "lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.12"^^xsd:string) "lipoxydase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.12"^^xsd:string) "carotene oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.12"^^xsd:string) "linoleate:oxygen 13-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.12"^^xsd:string) "fat oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "linoleate 13S-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.12"^^xsd:string) Annotation( "GOC:lb"^^xsd:string) "Catalysis of the reaction: linoleate + O2 = (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "http://www.chem.qmul.ac.uk/iubmb/enzyme/reaction/terp/carot.html"^^xsd:string) "Catalysis of the dehydrogenation of phytoene to produce a carotenoid intermediate such as phytofluene."^^xsd:string) AnnotationAssertion(rdfs:label "phytoene dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "glial cell line-derived neurotrophic factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "GDNF receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with glial cell line-derived neurotrophic factor and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "glial cell-derived neurotrophic factor receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with chlorophyll; any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment."^^xsd:string) AnnotationAssertion(rdfs:label "chlorophyll binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0192800981"^^xsd:string) "Interacting selectively and non-covalently with bacteriochlorophyll c, a chlorophyll of photosynthetic bacteria, for example green sulfur bacteria."^^xsd:string) AnnotationAssertion(rdfs:label "bacteriochlorophyll c binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-15 receptor binding"^^xsd:string) AnnotationAssertion( "IL-15"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-15 receptor."^^xsd:string) AnnotationAssertion( "interleukin-15 receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.6.3.1"^^xsd:string) "thyroid oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.3.1"^^xsd:string) "ThOX activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.3.1"^^xsd:string) "thyroid oxidase 2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.3.1"^^xsd:string) "NAD(P)H:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "NAD(P)H oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.3.1"^^xsd:string) "NADPH oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.3.1"^^xsd:string) "THOX2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.3.1"^^xsd:string) "Catalysis of the reaction: NAD(P)H + H+ + O2 = NAD(P)+ + hydrogen peroxide."^^xsd:string) AnnotationAssertion( "thyroid NADPH oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.3.1"^^xsd:string) "p138tox"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.3.1"^^xsd:string) "dual oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:10806195"^^xsd:string) "Catalysis of the reaction: NAD(P)H + O2 = NAD(P)H + O2-."^^xsd:string) AnnotationAssertion(rdfs:label "superoxide-generating NADPH oxidase activity"^^xsd:string) AnnotationAssertion( "cytochrome B-245"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "superoxide-generating NADPH oxidase activator activity"^^xsd:string) AnnotationAssertion( "neutrophil cytosol factor 2"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Increases the activity of the enzyme superoxide-generating NADPH oxidase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.-"^^xsd:string) Annotation( "PMID:10026151"^^xsd:string) "Catalysis of the reaction: selenocysteine + S-adenosyl-L-methionine = Se-methylselenocysteine + S-adenosyl-homocysteine."^^xsd:string) AnnotationAssertion(rdfs:label "selenocysteine methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.6"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.6"^^xsd:string) "catechol methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.6"^^xsd:string) "COMT II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.6"^^xsd:string) "MB-COMT (membrane-bound form of catechol-O-methyltransferase)"^^xsd:string) AnnotationAssertion(rdfs:label "catechol O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.6"^^xsd:string) "COMT I"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.6"^^xsd:string) "catecholamine O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.6"^^xsd:string) "S-COMT (soluble form of catechol-O-methyltransferase)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.6"^^xsd:string) "S-adenosyl-L-methionine:catechol O-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "hydroxycinnamate:CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "sinapoyl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "p-coumaryl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "4-coumarate:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "4-coumaryl-CoA synthetase activity"^^xsd:string) AnnotationAssertion( "4-coumarate:CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "caffeolyl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "p-hydroxycinnamoyl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "p-coumaryl-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "hydroxycinnamoyl CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "p-coumaroyl CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "p-coumaryl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "feruloyl CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "feruloyl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion( "4-coumarate-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "4CL"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "4-coumaroyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "4-coumaroyl-CoA synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-coumarate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "Catalysis of the reaction: ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "p-hydroxycinnamic acid:CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.12"^^xsd:string) "4-coumarate:coenzyme A ligase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with AMP, adenosine monophosphate."^^xsd:string) AnnotationAssertion(rdfs:label "AMP binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "antioxidant activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.74"^^xsd:string) "flavonone synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.74"^^xsd:string) "flavanone synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.74"^^xsd:string) "malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.74"^^xsd:string) "chalcone synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.74"^^xsd:string) "Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2."^^xsd:string) AnnotationAssertion( "CHS"^^xsd:string) AnnotationAssertion( "chalcone synthetase activity"^^xsd:string) AnnotationAssertion( "DOCS"^^xsd:string) AnnotationAssertion(rdfs:label "naringenin-chalcone synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ammonia ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the ligation of ammonia (NH3) to another substance via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.7"^^xsd:string) "kynurenine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.7"^^xsd:string) "Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.7"^^xsd:string) "kynurenine--oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.7"^^xsd:string) "kynurenine transaminase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.7"^^xsd:string) "kynurenine 2-oxoglutarate transaminase activity"^^xsd:string) AnnotationAssertion( "kynurenine-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.7"^^xsd:string) "L-kynurenine aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "kynurenine-oxoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.7"^^xsd:string) "L-kynurenine:2-oxoglutarate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.19.3"^^xsd:string) "fatty acid delta6-desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.19.3"^^xsd:string) "Catalysis of the reaction: linoleoyl-CoA + reduced acceptor + O2 = gamma-linolenoyl-CoA + acceptor + 2 H2O."^^xsd:string) AnnotationAssertion( "long-chain fatty acid delta(6)-desaturase activity"^^xsd:string) AnnotationAssertion( "linoleoyl-coenzyme A desaturase activity"^^xsd:string) AnnotationAssertion( "linoleate desaturase activity"^^xsd:string) AnnotationAssertion( "delta(6)-acyl CoA desaturase activity"^^xsd:string) AnnotationAssertion( "linoleic desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.19.3"^^xsd:string) "delta6-acyl CoA desaturase activity"^^xsd:string) AnnotationAssertion( "fatty acid 6-desaturase activity"^^xsd:string) AnnotationAssertion( "delta(6)-fatty acyl-CoA desaturase activity"^^xsd:string) AnnotationAssertion( "delta(6)-desaturase activity"^^xsd:string) AnnotationAssertion( "fatty acid delta(6)-desaturase activity"^^xsd:string) AnnotationAssertion(rdfs:label "linoleoyl-CoA desaturase activity"^^xsd:string) AnnotationAssertion( "linoleic acid desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.19.3"^^xsd:string) "delta6-fatty acyl-CoA desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.19.3"^^xsd:string) "long-chain fatty acid delta6-desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.19.3"^^xsd:string) "delta6-desaturase activity"^^xsd:string) AnnotationAssertion( "linoleoyl CoA desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.19.3"^^xsd:string) "linoleoyl-CoA,hydrogen-donor:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "CoA desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.19.1"^^xsd:string) Annotation( "EC:1.14.19.5"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = desaturated-acyl-CoA + acceptor + 2 H2O."^^xsd:string) AnnotationAssertion(rdfs:label "acyl-CoA desaturase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.21.3.1"^^xsd:string) Annotation( "RHEA:22431"^^xsd:string) "Catalysis of the reaction: N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O(2) = 2 H(2)O + isopenicillin N."^^xsd:string) AnnotationAssertion(rdfs:label "isopenicillin-N synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.3.1"^^xsd:string) "N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine:oxygen oxidoreductase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.3.1"^^xsd:string) "isopenicillin N synthase activity"^^xsd:string) AnnotationAssertion( "isopenicillin-N synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:R465-RXN"^^xsd:string) "Catalysis of the reaction: deethylsimazine + H2O = N-ethylammeline + chloride + H+."^^xsd:string) AnnotationAssertion(rdfs:label "N-ethylammeline chlorohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-alanine-pyruvate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.18"^^xsd:string) "omega-amino acid--pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.18"^^xsd:string) "L-alanine:3-oxopropanoate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.18"^^xsd:string) "Catalysis of the reaction: L-alanine + 2-oxopropanoate = pyruvate + beta-alanine."^^xsd:string) AnnotationAssertion( "beta-alanine-pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.18"^^xsd:string) "beta-alanine-alpha-alanine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.18"^^xsd:string) "beta-alanine--pyruvate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "steroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sphingomyelin phosphodiesterase activator activity"^^xsd:string) AnnotationAssertion( "neutral sphingomyelinase activator"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Increases the activity of the enzyme sphingomyelin phosphodiesterase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-N-acetylglucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.52"^^xsd:string) Annotation( "MetaCyc:3.2.1.52-RXN"^^xsd:string) "Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "HNK-1 sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9478973"^^xsd:string) "Catalysis of the synthesis of the HKK-1 carbohydrate epitope; adds a sulfate group to a precursor, GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R), forming sulfo-3GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R)."^^xsd:string) AnnotationAssertion( "HNK-1 sulphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "channel regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Modulates the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "channel inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stops, prevents, or reduces the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.10.1.1"^^xsd:string) "Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate."^^xsd:string) AnnotationAssertion(rdfs:label "N-sulfoglucosamine sulfohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.10.1.1"^^xsd:string) "sulphamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.10.1.1"^^xsd:string) "sulfoglucosamine sulfamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.10.1.1"^^xsd:string) "heparin sulfamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.10.1.1"^^xsd:string) "2-desoxy-D-glucoside-2-sulphamate sulphohydrolase (sulphamate sulphohydrolase)"^^xsd:string) AnnotationAssertion( "N-sulphoglucosamine sulphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.10.1.1"^^xsd:string) "N-sulfo-D-glucosamine sulfohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.94"^^xsd:string) "N-GlcNAc transferase activity"^^xsd:string) AnnotationAssertion( "UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.94"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein."^^xsd:string) AnnotationAssertion( "uridine diphosphoacetylglucosamine-protein acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion( "uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion( "UDP-N-acetyl-D-glucosamine:protein beta-N-acetyl-D-glucosaminyl-transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.122"^^xsd:string) "uridine diphosphogalactose-mucin beta-(1->3)-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.122"^^xsd:string) Annotation( "GOC:ma"^^xsd:string) "Catalysis of the addition of a galactosyl residue to a non-reducing O-linked N-acetylgalactosamine residue in an O-glycan."^^xsd:string) AnnotationAssertion( "Core 1 GalT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.122"^^xsd:string) "UDPgalactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.122"^^xsd:string) "UDP-galactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arginine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to an amino group of an arginine residue."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.125"^^xsd:string) Annotation( "EC:2.1.1.126"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12351636"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine."^^xsd:string) AnnotationAssertion(rdfs:label "protein-arginine N-methyltransferase activity"^^xsd:string) AnnotationAssertion( "PRMT activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.124"^^xsd:string) "cytochrome c-arginine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.124"^^xsd:string) "S-adenosyl-L-methionine:cytochrome c-arginine omega-N-methyltransferasea"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.124"^^xsd:string) "S-adenosyl-L-methionine:cytochrome c-arginine nomega-methyltransferasea"^^xsd:string) AnnotationAssertion(rdfs:label "[cytochrome c]-arginine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.124"^^xsd:string) Annotation( "GOC:ma"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + (cytochrome c)-arginine = S-adenosyl-L-homocysteine + (cytochrome c)-N(omega)-methyl-arginine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "[myelin basic protein]-arginine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.126"^^xsd:string) "protein methylase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.126"^^xsd:string) "S-adenosyl-L-methionine:myelin-basic-protein-arginine nomega-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.126"^^xsd:string) "myelin basic protein-arginine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.126"^^xsd:string) "S-adenosyl-L-methionine:myelin-basic-protein-arginine omega-N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.126"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + (myelin basic protein)-arginine = S-adenosyl-L-homocysteine + (myelin basic protein)-N(omega)-methyl-arginine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.126"^^xsd:string) "myelin basic protein methylase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.126"^^xsd:string) "myelin basic protein methylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lysine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12054878"^^xsd:string) "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate."^^xsd:string) AnnotationAssertion(rdfs:label "protein-lysine N-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "SK KCa channels"^^xsd:string) AnnotationAssertion( "small conductance KCa channels "^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "OMIM:602754"^^xsd:string) "Catalysis of the transmembrane transfer of potassium by a channel with a unit conductance of 2 to 20 picoSiemens that opens in response to stimulus by internal calcium ions. Small conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism."^^xsd:string) AnnotationAssertion(rdfs:label "small conductance calcium-activated potassium channel activity"^^xsd:string) AnnotationAssertion( "SK calcium-activated potassium channel activity "^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.42"^^xsd:string) Annotation( "RHEA:17660"^^xsd:string) "Catalysis of the reaction: acyl-CoA + glycerone phosphate = 1-acylglycerone 3-phosphate + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.42"^^xsd:string) "acyl-CoA:glycerone-phosphate O-acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycerone-phosphate O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.42"^^xsd:string) "dihydroxyacetone phosphate acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group."^^xsd:string) AnnotationAssertion(rdfs:label "CoA hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.2.2"^^xsd:string) "palmityl thioesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.2"^^xsd:string) "Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.2"^^xsd:string) "palmitoyl thioesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.2"^^xsd:string) "palmityl-CoA deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.2"^^xsd:string) "palmityl thioesterase I"^^xsd:string) AnnotationAssertion(rdfs:label "palmitoyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.2"^^xsd:string) "fatty acyl thioesterase I"^^xsd:string) AnnotationAssertion( "long-chain fatty-acyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.2"^^xsd:string) "palmitoyl-CoA deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.2"^^xsd:string) "palmitoyl coenzyme A hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "myristoyl-[acyl-carrier protein] hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "myristoyl-[acyl-carrier-protein] hydrolase activity"^^xsd:string) AnnotationAssertion( "tetradecanoyl-[acyl-carrier-protein] hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.14"^^xsd:string) Annotation( "MetaCyc:RXN-10727"^^xsd:string) "Catalysis of the reaction: myristoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + myristate."^^xsd:string) AnnotationAssertion( "myristoyl-ACP hydrolase activity"^^xsd:string) AnnotationAssertion( "tetradecanoyl-ACP hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.2.14"^^xsd:string) Annotation( "MetaCyc:RXN-9549"^^xsd:string) "Catalysis of the reaction: palmitoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + palmitate."^^xsd:string) AnnotationAssertion( "palmitoyl-ACP hydrolase activity"^^xsd:string) AnnotationAssertion( "palmitoyl-[acyl-carrier protein] hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "palmitoyl-[acyl-carrier-protein] hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acyl-[acyl-carrier-protein] hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.14"^^xsd:string) "S-acyl fatty acid synthase thioesterase activity"^^xsd:string) AnnotationAssertion( "acyl-[acyl-carrier protein] hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.14"^^xsd:string) "acyl-acyl carrier protein hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.14"^^xsd:string) Annotation( "MetaCyc:RXN-7902"^^xsd:string) "Catalysis of the reaction: acyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + a fatty acid."^^xsd:string) AnnotationAssertion( "acyl-ACP hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.14"^^xsd:string) "acyl-acyl-carrier-protein hydrolase activity"^^xsd:string) AnnotationAssertion( "acyl-ACP thioesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.14"^^xsd:string) "acyl-ACP-hydrolase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of a lipid or phospholipid."^^xsd:string) AnnotationAssertion(rdfs:label "lipase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "tRNA (uridine) methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA (uracil) methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a methyl group from a donor to a uracil residue in a tRNA molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule."^^xsd:string) AnnotationAssertion(rdfs:label "kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phosphatidylinositol 3-kinase activity, class III"^^xsd:string) AnnotationAssertion( "phosphatidylinositol 3-kinase activity, class II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.137"^^xsd:string) "Vps34p"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.137"^^xsd:string) "ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase activity"^^xsd:string) AnnotationAssertion( "1-phosphatidylinositol 3-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.137"^^xsd:string) "type I phosphatidylinositol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.137"^^xsd:string) "type III phosphoinositide 3-kinase activity"^^xsd:string) AnnotationAssertion( "phosphatidylinositol 3-kinase, class I, catalyst activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.137"^^xsd:string) "PI3-kinase activity"^^xsd:string) AnnotationAssertion( "PI3K"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.137"^^xsd:string) Annotation( "RHEA:12712"^^xsd:string) "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "1-phosphatidylinositol-3-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.137"^^xsd:string) "PtdIns-3-kinase activity"^^xsd:string) AnnotationAssertion( "phosphatidylinositol 3-kinase activity, class I"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "phosphatidylinositol monophosphate kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.-"^^xsd:string) Annotation( "PMID:9759495"^^xsd:string) "Catalysis of the reaction: ATP + a phosphatidylinositol phosphate = ADP + a phosphatidylinositol bisphosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.68"^^xsd:string) "PIP kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.68"^^xsd:string) "diphosphoinositide kinase activity"^^xsd:string) AnnotationAssertion( "1-phosphatidylinositol-4-phosphate kinase, class IA"^^xsd:string) AnnotationAssertion( "1-phosphatidylinositol-4-phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.68"^^xsd:string) "phosphatidylinositol 4-phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.68"^^xsd:string) "type I PIP kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.68"^^xsd:string) "PtdIns(4)P-5-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.68"^^xsd:string) "ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion( "1-phosphatidylinositol-4-phosphate kinase, class IB"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.68"^^xsd:string) Annotation( "RHEA:14428"^^xsd:string) "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.68"^^xsd:string) "phosphatidylinositol-4-phosphate 5-kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-phosphatidylinositol-4-phosphate 5-kinase activity"^^xsd:string) AnnotationAssertion( "PIP5K"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "1-phosphatidylinositol-5-phosphate kinase"^^xsd:string) AnnotationAssertion(rdfs:label "1-phosphatidylinositol-5-phosphate 4-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.149"^^xsd:string) "ATP:1-phosphatidyl-1D-myo-inositol-5-phosphate 4-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.149"^^xsd:string) "Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.149"^^xsd:string) "type II PIP kinase activity"^^xsd:string) AnnotationAssertion( "PIP4K"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hb"^^xsd:string) "Catalysis of the reaction: myo-inositol bisphosphate + H2O = myo-inositol phosphate + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "inositol bisphosphate phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.67"^^xsd:string) "MMAC1"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.67"^^xsd:string) "phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.67"^^xsd:string) "Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-4,5-bisphosphate + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.67"^^xsd:string) "1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 3-phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.66"^^xsd:string) "inositol polyphosphate 4-phosphatase type II activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.66"^^xsd:string) "1-phosphatidyl-1D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.66"^^xsd:string) Annotation( "GOC:hb"^^xsd:string) "Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "activin receptor activity, type I"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:8622651"^^xsd:string) "Combining with activin-bound type II activin receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of activin signals."^^xsd:string) AnnotationAssertion( "type I activin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "activin receptor activity, type II"^^xsd:string) AnnotationAssertion( "type II activin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:8622651"^^xsd:string) "Combining with activin to initiate a change in cell activity; upon ligand binding, binds to and catalyses the phosphorylation of a type I activin receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jsg"^^xsd:string) "Catalysis of the reaction: palmitoyl-CoA + O2 = trans-2,3-dehydropalmitoyl-CoA + hydrogen peroxide."^^xsd:string) AnnotationAssertion(rdfs:label "palmitoyl-CoA oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jsg"^^xsd:string) "Catalysis of the reaction: pristanoyl-CoA + O2 = trans-2,3-dehydropristanoyl-CoA + hydrogen peroxide."^^xsd:string) AnnotationAssertion(rdfs:label "pristanoyl-CoA oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.18"^^xsd:string) "NG,NG-dimethyl-L-arginine dimethylamidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.18"^^xsd:string) "N(G),N(G)-dimethylarginine dimethylaminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.18"^^xsd:string) "Catalysis of the reaction: N(G),N(G)-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline."^^xsd:string) AnnotationAssertion(rdfs:label "dimethylargininase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.18"^^xsd:string) "NG,NG-dimethylarginine dimethylaminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.18"^^xsd:string) "dimethylarginine dimethylaminohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.141"^^xsd:string) "(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.141"^^xsd:string) "11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.141"^^xsd:string) "15-hydroxyprostanoic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.141"^^xsd:string) "NAD-specific 15-hydroxyprostaglandin dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.141"^^xsd:string) "NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (type I)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.141"^^xsd:string) "15-OH-PGDH"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.141"^^xsd:string) "prostaglandin dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.141"^^xsd:string) "15-hydroxyprostaglandin dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "15-hydroxyprostaglandin dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.141"^^xsd:string) "Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CoA-ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: substrate + ATP + CoASH = AMP + diphosphate + substrate-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carnitine O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an acyl group to an oxygen atom on the carnitine molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "acetylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an acetyl group to an acceptor molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an acyl group to a carbon atom on the acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "C-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "palmitoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an acyl group to an oxygen atom on the acylglycerol molecule."^^xsd:string) AnnotationAssertion(rdfs:label "acylglycerol O-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an acyl group to an oxygen atom on the serine molecule."^^xsd:string) AnnotationAssertion(rdfs:label "serine O-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an acetyl group to an oxygen atom on the acceptor molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an octanoyl group to an oxygen atom on the acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "O-octanoyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an octanoyl (CH3-[CH2]6-CO-) group to an acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "octanoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "O-palmitoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a palmitoyl group to an oxygen atom on the acceptor molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an acyl group to a sulfur atom on the acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "S-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an acetyl group to a sulfur atom on the acceptor molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a malonyl group to a sulfur atom on the acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "S-malonyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a malonyl (HOOC-CH2-CO-) group to an acceptor molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the joining of a carboxyl group to a molecule that is attached to CoA, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "CoA carboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.62"^^xsd:string) "S-adenosyl-L-methionine:mRNA (2'-O-methyladenosine-6-N-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.62"^^xsd:string) "S-adenosyl-L-methionine:mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.62"^^xsd:string) "messenger ribonucleate 2'-O-methyladenosine NG-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.62"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + m(7)G(5')pppAm = S-adenosyl-L-homocysteine + m(7)G(5')pppm(6)Am."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "tRNA (guanosine) methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.-"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylguanine."^^xsd:string) AnnotationAssertion(rdfs:label "tRNA (guanine) methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.-"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methyladenine."^^xsd:string) AnnotationAssertion(rdfs:label "tRNA (adenine) methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.-"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylcytosine."^^xsd:string) AnnotationAssertion(rdfs:label "tRNA (cytosine) methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.29"^^xsd:string) "transfer RNA cytosine 5-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.29"^^xsd:string) "S-adenosyl-L-methionine:tRNA (cytosine-5-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.29"^^xsd:string) "transfer ribonucleate cytosine 5-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.29"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 5-methylcytosine."^^xsd:string) AnnotationAssertion(rdfs:label "tRNA (cytosine-5-)-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.36"^^xsd:string) "adenine-1-methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.36"^^xsd:string) "transfer RNA (adenine-1) methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.36"^^xsd:string) "transfer ribonucleate adenine 1-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA (adenine-N1-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.36"^^xsd:string) "1-methyladenine transfer RNA methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.36"^^xsd:string) "S-adenosyl-L-methionine:tRNA (adenine-N1-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.36"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methyladenine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.36"^^xsd:string) "S-adenosyl-L-methionine:tRNA (adenine-1-N-)-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tRNA (adenine-N6-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.55"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N6-methyladenine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.55"^^xsd:string) "S-adenosyl-L-methionine:tRNA (adenine-N6-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.55"^^xsd:string) "S-adenosyl-L-methionine:tRNA (adenine-6-N-)-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tRNA-uridine aminocarboxypropyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.25"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA uridine = 5'-methylthioadenosine + tRNA 3-(3-amino-3-carboxypropyl)-uridine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.25"^^xsd:string) "S-adenosyl-L-methionine:tRNA-uridine 3-(3-amino-3-carboxypropyl)transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "rRNA (adenine) methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.-"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyladenine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.-"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylcytosine."^^xsd:string) AnnotationAssertion(rdfs:label "rRNA (cytosine) methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.-"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine."^^xsd:string) AnnotationAssertion(rdfs:label "rRNA (guanine) methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.-"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyluridine."^^xsd:string) AnnotationAssertion(rdfs:label "rRNA (uridine) methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "transfer ribonucleic adenylyl (cytidylyl) transferase"^^xsd:string) AnnotationAssertion( "CTP:tRNA cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "ribonucleic cytidylic cytidylic adenylic pyrophosphorylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "transfer-RNA nucleotidyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "ATP(CTP):tRNA nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "tRNA adenylyl(cytidylyl)transferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "CTP(ATP):tRNA nucleotidyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "ATP (CTP):tRNA nucleotidyltransferase"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "ribonucleic cytidylyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "transfer ribonucleate nucleotidyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "-C-C-A pyrophosphorylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "transfer ribonucleic acid nucleotidyl transferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "transfer ribonucleate cytidylyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "transfer ribonucleate adenylyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "ATP(CTP)-tRNA nucleotidyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "Catalysis of the reaction: CTP + tRNA(n) = diphosphate + tRNA(n+1)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "tRNA CCA-diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "tRNA CCA-pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "transfer ribonucleic-terminal trinucleotide nucleotidyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.21"^^xsd:string) "transfer RNA adenylyltransferase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tRNA-queuosine beta-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.110"^^xsd:string) "GDP-mannose:tRNAAsp-queuosine O-5''-beta-D-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.110"^^xsd:string) "Catalysis of the reaction: GDP-mannose + tRNA(Asp)-queuosine = GDP + tRNA(Asp)-O-5''-beta-D-mannosylqueuosine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "bidentate RNase III activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15242644"^^xsd:string) "Catalysis of the digestion of double-stranded RNAs into 20 to 30-nucleotide products. These products typically associate to the RNA-induced silencing complex and serve as guide RNAs for posttranslational RNA interference."^^xsd:string) AnnotationAssertion(rdfs:label "bidentate ribonuclease III activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an acetyl group to a carbon atom on the acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "C-acetyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "C-palmitoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a palmitoyl group to a carbon atom on the acceptor molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.-"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments."^^xsd:string) AnnotationAssertion(rdfs:label "pyrophosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.5"^^xsd:string) "Zn(2+)-exporting ATPase activity"^^xsd:string) AnnotationAssertion( "zinc exporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.5"^^xsd:string) "ATP phosphohydrolase (Zn2+-exporting)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.5"^^xsd:string) "P(1B)-type ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "zinc-exporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.5"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(in) -> ADP + phosphate + Zn2+(out)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.5"^^xsd:string) "P1B-type ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.5"^^xsd:string) "zinc-translocating P-type ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.5"^^xsd:string) "AtHMA4"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.5"^^xsd:string) "Zn(II)-translocating P-type ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.5"^^xsd:string) "Zn2+-exporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.52"^^xsd:string) "ATP phosphohydrolase (chloroplast protein-importing)"^^xsd:string) AnnotationAssertion(rdfs:label "chloroplast protein-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "chloroplast protein ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.52"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the chloroplast stroma."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tryptophan hydroxylase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Increases the activity of the enzyme tryptophase hydroxylase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "structural constituent of peritrophic membrane"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_sensu"^^xsd:string) Annotation( "ISBN:0879694238"^^xsd:string) "The action of a molecule that contributes to the structural integrity of the peritrophic membrane, a tubular sheath of cuticle that shields the epithelial cells of the midgut from the gut contents. An example of this is found in Drosophila melanogaster."^^xsd:string) AnnotationAssertion( "structural constituent of peritrophic matrix"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced."^^xsd:string) AnnotationAssertion( "redox activity"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on other substrates"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "G-protein-coupled neurotensin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "neurotensin receptor activity, G-protein coupled"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10390649"^^xsd:string) "Combining with the tridecapeptide neurotensin to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state."^^xsd:string) AnnotationAssertion( "neurotensin receptor activity, G protein coupled"^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled neurotensin receptor activity"^^xsd:string) AnnotationAssertion( "G protein coupled neurotensin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:8662823"^^xsd:string) "Combining with a C-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif."^^xsd:string) AnnotationAssertion(rdfs:label "C-C chemokine receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:8662823"^^xsd:string) "Combining with a C-X-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X-C chemokine has a single amino acid between the first two cysteines of the characteristic four cysteine motif."^^xsd:string) AnnotationAssertion(rdfs:label "C-X-C chemokine receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with a C-X3-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X3-C chemokine has three amino acids between the first two cysteines of the characteristic four-cysteine motif."^^xsd:string) AnnotationAssertion(rdfs:label "C-X3-C chemokine receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "substance P receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Combining with substance P, the peptide Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met, to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "neuromedin L receptor activity"^^xsd:string) AnnotationAssertion( "neurokinin A receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "substance K receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Combining with substance K, the peptide His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met, to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Combining with neuromedin K, the peptide Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "neurokinin B receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "neuromedin K receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "orexin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Combining with orexin to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with a protein hormone to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "protein-hormone receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "prostaglandin I receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "prostacyclin receptor activity"^^xsd:string) AnnotationAssertion( "PGI(2) receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Combining with prostacyclin (PGI(2)) to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "PGI receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Combining with a nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule."^^xsd:string) AnnotationAssertion(rdfs:label "nucleotide receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "pheromone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:26013"^^xsd:string) Annotation( "GOC:hjd"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Combining with a pheromone to initiate a change in cell activity. A pheromone is a substance used in olfactory communication between organisms of the same species eliciting a change in sexual or social behavior."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "protease activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Increases the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds."^^xsd:string) AnnotationAssertion(rdfs:label "peptidase activator activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mtg_apoptosis"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Increases the activity of a peptidase that is involved in the apoptotic process."^^xsd:string) AnnotationAssertion( "apoptotic protease activator activity"^^xsd:string) AnnotationAssertion(rdfs:label "peptidase activator activity involved in apoptotic process"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.74"^^xsd:string) "long-chain enoyl coenzyme A hydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "long-chain-enoyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.74"^^xsd:string) "Catalysis of the reaction: a long-chain (3S)-3-hydroxyacyl-CoA = a long-chain trans-2-enoyl-CoA + H2O. A long-chain acyl-CoA is an acyl-CoA thioester where the acyl chain contains 13 to 22 carbon atoms."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.74"^^xsd:string) "long-chain-(3S)-3-hydroxyacyl-CoA hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.211"^^xsd:string) "beta-hydroxyacyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.211"^^xsd:string) "long-chain 3-hydroxyacyl coenzyme A dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.211"^^xsd:string) "LCHAD"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.211"^^xsd:string) "long-chain-(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15904"^^xsd:string) Annotation( "EC:1.1.1.211"^^xsd:string) Annotation( "GOC:pde"^^xsd:string) "Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a long-chain fatty acid residue. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22."^^xsd:string) AnnotationAssertion(rdfs:label "long-chain-3-hydroxyacyl-CoA dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-13 receptor activity"^^xsd:string) AnnotationAssertion( "IL-13R"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-13 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-13 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-12 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-12 receptor activity"^^xsd:string) AnnotationAssertion( "IL-12R"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-12 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-14 receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-14 receptor activity"^^xsd:string) AnnotationAssertion( "IL-14R"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-14 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19251046"^^xsd:string) "GIP receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19251046"^^xsd:string) "glucose-dependent insulinotropic polypeptide receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:8243312"^^xsd:string) "Combining with gastric inhibitory peptide (GIP) and transmitting the signal across the membrane to activate an associated G-protein."^^xsd:string) AnnotationAssertion(rdfs:label "gastric inhibitory peptide receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12529933"^^xsd:string) "Combining with growth hormone-releasing hormone to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "growth hormone-releasing hormone receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19805477"^^xsd:string) "The action characteristic of pituitary adenylate cyclase activating polypeptide, a peptide produced in the hypothalamus that binds to receptors to exert pleiotropic effects including control of neurotransmitter release, vasodilation, bronchodilation, activation of intestinal motility, increase in insulin and histamine secretion, immune modulation, and stimulation of cell proliferation and differentiation."^^xsd:string) AnnotationAssertion(rdfs:label "pituitary adenylate cyclase activating polypeptide activity"^^xsd:string) AnnotationAssertion( "pituitary adenylyl cyclase activating polypeptide activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "latrophilin"^^xsd:string) AnnotationAssertion(rdfs:label "latrotoxin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:10025961"^^xsd:string) "Combining with alpha-latrotoxin, a potent presynaptic neurotoxin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:11739376"^^xsd:string) "Assists in the delivery of metal ions to target proteins or compartments."^^xsd:string) AnnotationAssertion(rdfs:label "metallochaperone activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "copper chaperone activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10790544"^^xsd:string) Annotation( "PMID:11739376"^^xsd:string) "Assists in the delivery of copper ions to target proteins or compartments."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "superoxide dismutase copper chaperone activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9295278"^^xsd:string) Annotation( "http://link.springer-ny.com/link/service/journals/00335/papers/0011005/00110409.html"^^xsd:string) "A copper chaperone activity that specifically delivers copper to the Cu-Zn superoxide dismutase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cyclin-dependent protein kinase 5 activator, intrinsic catalyst activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Increases the activity of cyclin-dependent protein kinase 5."^^xsd:string) AnnotationAssertion(rdfs:label "cyclin-dependent protein kinase 5 activator activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cyclin-dependent protein kinase 5 activator, intrinsic regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Modulation of the activity of cyclin-dependent protein kinase 5 activator."^^xsd:string) AnnotationAssertion(rdfs:label "cyclin-dependent protein kinase 5 activator regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "G2/M-specific cyclin"^^xsd:string) AnnotationAssertion( "cyclin-dependent protein kinase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pr"^^xsd:string) Annotation( "GOC:rn"^^xsd:string) Annotation( "PMID:7877684"^^xsd:string) Annotation( "PMID:9442875"^^xsd:string) "Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins."^^xsd:string) AnnotationAssertion( "G1/S-specific cyclin"^^xsd:string) AnnotationAssertion(rdfs:label "cyclin-dependent protein serine/threonine kinase regulator activity"^^xsd:string) AnnotationAssertion( "cyclin-dependent protein kinase, intrinsic regulator activity"^^xsd:string) AnnotationAssertion( "cyclin"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with glycine, aminoethanoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "glycine binding"^^xsd:string) AnnotationAssertion( "aminoethanoic acid binding"^^xsd:string) AnnotationAssertion( "aminoacetic acid binding"^^xsd:string) AnnotationAssertion( "Gly binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glutamic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with glutamate, the anion of 2-aminopentanedioic acid."^^xsd:string) AnnotationAssertion(rdfs:label "glutamate binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thienylcyclohexylpiperidine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with thienylcyclohexylpiperidine."^^xsd:string) AnnotationAssertion( "TCP binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents."^^xsd:string) AnnotationAssertion(rdfs:label "amino acid binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.2.5"^^xsd:string) "L-glutaminyl-peptide gamma-glutamyltransferase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.5"^^xsd:string) "glutaminyl-tRNA cyclotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.5"^^xsd:string) "Catalysis of the reaction: L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.5"^^xsd:string) "glutaminyl cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.5"^^xsd:string) "glutaminyl-transfer ribonucleate cyclotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutaminyl-peptide cyclotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "growth hormone-releasing hormone activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "GHRF activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "The action characteristic of growth hormone-releasing hormone, any of a family of peptide hormones that act on the anterior pituitary to stimulate the secretion of growth hormone and exert a trophic effect on the gland."^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "GHRH activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on CH-OH group of donors"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on the CH-OH group of donors, other acceptors"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0582227089"^^xsd:string) "Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate."^^xsd:string) AnnotationAssertion(rdfs:label "malate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-oxoproline reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.104"^^xsd:string) "4-hydroxy-L-proline:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.104"^^xsd:string) "hydroxyproline oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.104"^^xsd:string) "Catalysis of the reaction: 4-hydroxy-L-proline + NAD+ = 4-oxoproline + NADH + H+."^^xsd:string) AnnotationAssertion( "hydroxy-L-proline oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.81"^^xsd:string) "NADH:hydroxypyruvate reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydroxypyruvate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.81"^^xsd:string) "Catalysis of the reaction: D-glycerate + NADP+ = hydroxypyruvate + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.81"^^xsd:string) "D-glycerate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.81"^^xsd:string) "D-glycerate:NADP+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.81"^^xsd:string) "beta-hydroxypyruvate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.44"^^xsd:string) "feruloyl coenzyme A reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.44"^^xsd:string) "p-hydroxycinnamoyl coenzyme A reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cinnamoyl-CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.44"^^xsd:string) "Catalysis of the reaction: cinnamaldehyde + CoA + NADP+ = cinnamoyl-CoA + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.44"^^xsd:string) "cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating)"^^xsd:string) AnnotationAssertion( "cinnamoyl CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.44"^^xsd:string) "cinnamoyl-CoA:NADPH reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.44"^^xsd:string) "cinnamoyl-coenzyme A reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.44"^^xsd:string) "feruloyl-CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.44"^^xsd:string) "ferulyl-CoA reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a cytochrome."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces oxygen."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulphide as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulphur protein as acceptor"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces an iron-sulfur protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on the CH-CH group of donors, other acceptors"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-CH group of donors"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "12-oxophytodienoate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.42"^^xsd:string) "12-oxo-phytodienoic acid reductase activity"^^xsd:string) AnnotationAssertion( "12-oxo-phytodienoate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.42"^^xsd:string) "8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-enyl}cyclopentyl]octanoate:NADP+ 4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.42"^^xsd:string) Annotation( "RHEA:21891"^^xsd:string) "Catalysis of the reaction: 8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-en-1-yl}cyclopentyl]octanoate + NADP(+) = (15Z)-12-oxophyto-10,15-dienoate + H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.33"^^xsd:string) "NADPH2-protochlorophyllide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.33"^^xsd:string) "NADPH-protochlorophyllide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.33"^^xsd:string) "protochlorophyllide photooxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.33"^^xsd:string) "protochlorophyllide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.33"^^xsd:string) "NADPH-protochlorophyllide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.33"^^xsd:string) "Catalysis of the reaction: chlorophyllide a + NADP+ = protochlorophyllide + NADPH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "protochlorophyllide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.33"^^xsd:string) "chlorophyllide-a:NADP+ 7,8-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.-"^^xsd:string) "acyl-ACP dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "enoyl-[acyl-carrier-protein] reductase activity"^^xsd:string) AnnotationAssertion( "enoyl-acyl carrier protein reductase"^^xsd:string) AnnotationAssertion( "enoyl-ACP reductase activity"^^xsd:string) AnnotationAssertion( "enoyl-[acyl-carrier protein] reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.9"^^xsd:string) Annotation( "GOC:rb"^^xsd:string) "Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD(P)+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NAD(P)H + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a cytochrome."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.2.3"^^xsd:string) "L-galactono-gamma-lactone dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.2.3"^^xsd:string) "Catalysis of the reaction: L-galactono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.2.3"^^xsd:string) "GLDase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.2.3"^^xsd:string) "L-galactonolactone dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactonolactone dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.2.3"^^xsd:string) "L-galactono-1,4-lactone:ferricytochrome-c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.2.3"^^xsd:string) "GLDHase activity"^^xsd:string) AnnotationAssertion( "L-galactono-1,4-lactone dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.2.3"^^xsd:string) "L-galactono-gamma-lactone:ferricytochrome-c oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces oxygen."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a quinone or related compound."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on the CH-CH group of donors, iron-sulphur protein as acceptor"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-NH2 group of donors"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a cytochrome molecule."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-NH2 group of donors, cytochrome as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a disulfide group."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on the CH-NH2 group of donors, disulphide as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulfur protein as acceptor"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulphur protein as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-NH group of donors"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on the CH-NH group of donors, other acceptors"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces NAD or NADP."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces oxygen."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces disulfide."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on the CH-NH group of donors, disulphide as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces quinone or similar compound."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "NAD(P)H dehydrogenase"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on NAD(P)H"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on NADH or NADPH"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on NADH or NADPH, other acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces NAD+ or NADP."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on NAD or NADPH, NAD or NADP as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a heme protein."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on NADH or NADPH, haem protein as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.6.5.4"^^xsd:string) "AFR"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.4"^^xsd:string) "NADH:ascorbate radical oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "monodehydroascorbate reductase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.4"^^xsd:string) "NADH:semidehydroascorbic acid oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.4"^^xsd:string) "ascorbic free radical reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.4"^^xsd:string) "ascorbate free radical reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.4"^^xsd:string) "SDA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.4"^^xsd:string) "MDHA"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.4"^^xsd:string) "AFR-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.4"^^xsd:string) "MDAsA reductase (NADPH)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.4"^^xsd:string) "NADH:monodehydroascorbate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.4"^^xsd:string) "ascorbate free-radical reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.4"^^xsd:string) "semidehydroascorbate reductase activity"^^xsd:string) AnnotationAssertion( "monodehydroascorbate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.4"^^xsd:string) "NADH:AFR oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.4"^^xsd:string) "Catalysis of the reaction: NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.4"^^xsd:string) "NADH-semidehydroascorbate oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a nitrogenous group."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on other nitrogenous compounds as donors"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a cytochrome."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces oxygen."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an iron-sulfur protein."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulphur protein as acceptor"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "oxidoreductase activity, acting on sulphur group of donors"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on a sulfur group of donors"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on sulfur group of donors, other acceptors"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "oxidoreductase activity, acting on NADH or NADPH, disulphide as acceptor"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on sulphur group of donors, NAD or NADP as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces NAD or NADP."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a cytochrome."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on sulphur group of donors, cytochrome as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces oxygen."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on sulphur group of donors, oxygen as acceptor"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "oxidoreductase activity, acting on sulphur group of donors, disulphide as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces quinone or a related compound."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on sulphur group of donors, quinone or similar compound as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces an iron-sulfur protein."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on sulphur group of donors, iron-sulphur protein as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on haem group of donors"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on a heme group of donors"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on heme group of donors, other acceptors"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces oxygen."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on haem group of donors, oxygen as acceptor"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a nitrogenous group."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on haem group of donors, nitrogenous group as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a diphenol or related substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on diphenols and related substances as donors"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces NAD or NADP."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on diphenols and related substances as donors, NAD or NADP as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a cytochrome."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces oxygen."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on peroxide as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-ascorbate peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.11"^^xsd:string) "ascorbic acid peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.11"^^xsd:string) "L-ascorbate:hydrogen-peroxide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.11"^^xsd:string) "L-ascorbic acid-specific peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.11"^^xsd:string) "ascorbate peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.11"^^xsd:string) "Catalysis of the reaction: L-ascorbate + hydrogen peroxide = dehydroascorbate + 2 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.11"^^xsd:string) "L-ascorbic acid peroxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "manganese peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.13"^^xsd:string) "peroxidase-M2"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.13"^^xsd:string) "Catalysis of the reaction: 2 Mn2+ + 2 H+ + hydrogen peroxide = 2 Mn3+ + 2 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.13"^^xsd:string) "Mn-dependent peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.13"^^xsd:string) "Mn(II):hydrogen-peroxide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.13"^^xsd:string) "Mn-dependent (NADH-oxidizing) peroxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.11.1.14"^^xsd:string) "LiP activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.14"^^xsd:string) "ligninase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.14"^^xsd:string) "diarylpropane oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.14"^^xsd:string) "Catalysis of the reaction: (3,4-dimethoxyphenyl)methanol + H2O2 = 3,4-dimethoxybenzaldehyde + 2 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.14"^^xsd:string) "ligninase I activity"^^xsd:string) AnnotationAssertion(rdfs:label "diarylpropane peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.14"^^xsd:string) "diarylpropane:oxygen,hydrogen-peroxide oxidoreductase (C-C-bond-cleaving)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.14"^^xsd:string) "1,2-bis(3,4-dimethoxyphenyl)propane-1,3-diol:hydrogen-peroxide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.14"^^xsd:string) "lignin peroxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "vanadium chloroperoxidase activity"^^xsd:string) AnnotationAssertion( "heme chloroperoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.10"^^xsd:string) "Catalysis of the reaction: 2 R-H + 2 chloride + hydrogen peroxide = 2 R-Cl + 2 H2O."^^xsd:string) AnnotationAssertion( "flavin-haem chloroperoxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "chloride peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.10"^^xsd:string) "chloride:hydrogen-peroxide oxidoreductase"^^xsd:string) AnnotationAssertion( "cofactor-free chloroperoxidase activity"^^xsd:string) AnnotationAssertion( "haem chloroperoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.10"^^xsd:string) "chloroperoxidase activity"^^xsd:string) AnnotationAssertion( "flavin-heme chloroperoxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.11.1.1"^^xsd:string) "NADH-peroxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "NADH peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.1"^^xsd:string) Annotation( "RHEA:18512"^^xsd:string) "Catalysis of the reaction: H(2)O(2) + H(+) + NADH = 2 H(2)O + NAD(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.1"^^xsd:string) "nicotinamide adenine dinucleotide peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.1"^^xsd:string) "NAD peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.1"^^xsd:string) "NADH:hydrogen-peroxide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.1"^^xsd:string) "DPNH peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.1"^^xsd:string) "diphosphopyridine nucleotide peroxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on hydrogen as donor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on hydrogen as donor, other acceptors"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces NAD or NADP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on hydrogen as donor, cytochrome as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces a cytochrome."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "oxidoreductase activity, acting on hydrogen as donor, iron-sulphur protein as acceptor"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces an iron-sulfur protein."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous"^^xsd:string) AnnotationAssertion( "oxygenase"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and molecular oxygen is incorporated into a donor."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and one oxygen atom is incorporated into a donor."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2-oxoglutarate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor."^^xsd:string) AnnotationAssertion( "2-oxoglutarate-dependent dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.15"^^xsd:string) "gibberellin 3beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.15"^^xsd:string) "gibberellin 3-beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.15"^^xsd:string) "(gibberrellin-20),2-oxoglutarate: oxygen oxidoreductase (3beta-hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "gibberellin 3-beta-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.15"^^xsd:string) Annotation( "GOC:kad"^^xsd:string) "Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 3-beta-hydroxy-gibberellin + succinate + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.15"^^xsd:string) "gibberellin 3beta-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.15"^^xsd:string) "(gibberellin-20),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen are incorporated into one donor."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.11"^^xsd:string) "CA4H activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.11"^^xsd:string) "cytochrome P450 cinnamate 4-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.11"^^xsd:string) "cinnamate 4-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.11"^^xsd:string) "t-cinnamic acid hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.11"^^xsd:string) "cinnamic acid p-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.11"^^xsd:string) "cinnamate hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.11"^^xsd:string) "trans-cinnamic acid 4-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.11"^^xsd:string) "oxygenase, cinnamate 4-mono-"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.11"^^xsd:string) "cinnamate 4-monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trans-cinnamate 4-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.11"^^xsd:string) "cinnamic acid 4-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.11"^^xsd:string) "cinnamic 4-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.11"^^xsd:string) "cinnamic acid 4-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.11"^^xsd:string) "trans-cinnamate,NADPH:oxygen oxidoreductase (4-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.11"^^xsd:string) "trans-cinnamate 4-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.11"^^xsd:string) "Catalysis of the reaction: trans-cinnamate + NADPH + H+ + O2 = 4-hydroxycinnamate + NADP+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.11"^^xsd:string) "hydroxylase, cinnamate 4-"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.21"^^xsd:string) "flavonoid 3'-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.21"^^xsd:string) "NADPH:flavonoid-3'-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.21"^^xsd:string) "flavonoid,NADPH:oxygen oxidoreductase (3'-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.21"^^xsd:string) "flavonoid 3-monooxygenase (erroneous)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.21"^^xsd:string) "Catalysis of the reaction: a flavonoid + NADPH + H+ + O2 = 3'-hydroxyflavonoid + NADP+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.21"^^xsd:string) "flavonoid 3-hydroxylase (erroneous)"^^xsd:string) AnnotationAssertion(rdfs:label "flavonoid 3'-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cytochrome P450 CYP19"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.1"^^xsd:string) "flavoprotein-linked monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.1"^^xsd:string) "cytochrome p450 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.1"^^xsd:string) "microsomal P-450"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.1"^^xsd:string) "aryl-4-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.1"^^xsd:string) "microsomal p450 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.1"^^xsd:string) "xenobiotic monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.1"^^xsd:string) "substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.1"^^xsd:string) "aryl hydrocarbon hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.1"^^xsd:string) "microsomal monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.1"^^xsd:string) "flavoprotein monooxygenase activity"^^xsd:string) AnnotationAssertion( "unspecific monooxygenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulphur protein as one donor, and incorporation of one atom of oxygen"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced iron-sulfur protein and one other donor, and one atom of oxygen is incorporated into one donor."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced pteridine and one other donor, and one atom of oxygen is incorporated into one donor."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced ascorbate and one other donor, and one atom of oxygen is incorporated into one donor."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and one atom of oxygen is incorporated into one donor."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced to two molecules of water."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carotene 7,8-desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.30"^^xsd:string) "Catalysis of the reaction: neurosporene + donor-H2 + O2 = lycopene + acceptor + 2 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.30"^^xsd:string) "carotene,hydrogen-donor:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.30"^^xsd:string) "zeta-carotene desaturase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "delta12-fatty acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.33"^^xsd:string) "delta-12 fatty acid acetylenase activity"^^xsd:string) AnnotationAssertion( "D12-fatty acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.33"^^xsd:string) "delta12 fatty acid acetylenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.33"^^xsd:string) "linoleate, hydrogen-donor:oxygen oxidoreductase (Delta12-unsaturating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.33"^^xsd:string) "crepenynate synthase activity"^^xsd:string) AnnotationAssertion( "linoleate delta-12-fatty acid acetylenase (desaturase) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.33"^^xsd:string) Annotation( "RHEA:23459"^^xsd:string) "Catalysis of the reaction: AH(2) + linoleate + O(2) = A + crepenynate + 2 H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.33"^^xsd:string) "linoleate delta12-fatty acid acetylenase (desaturase)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on superoxide radicals as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a superoxide radical (O2- or O2.-) acts as a hydrogen or electron acceptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, oxidizing metal ions"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and NAD+ or NADP+ acts as an electron acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and oxygen acts as an electron acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, oxidizing metal ions, oxygen as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on CH or CH2 groups"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on CH or CH2 groups, other acceptors"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a disulfide group."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on CH or CH2 groups, disulphide as acceptor"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on iron-sulphur proteins as donors"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on iron-sulfur proteins as donors"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces NAD or NADP."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces dinitrogen."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on reduced flavodoxin as donor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces dinitrogen."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on reduced flavodoxin as donor, dinitrogen as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "transferase activity, transferring one-carbon groups"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroxymethyl-, formyl- and related transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a hydroxymethyl- or formyl group from one compound (donor) to another (acceptor)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a carboxyl- or carbamoyl group from one compound (donor) to another (acceptor)."^^xsd:string) AnnotationAssertion( "carboxyl- and carbamoyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "carboxyl- or carbamoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of an aldehyde or ketonic group from one compound (donor) to another (acceptor)."^^xsd:string) AnnotationAssertion( "transketolase or transaldolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "transferase activity, transferring aldehyde or ketonic groups"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "transferase activity, transferring acyl groups"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "transferase activity, transferring acyl groups other than amino-acyl groups"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1"^^xsd:string) "transferase activity, transferring groups other than amino-acyl groups"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a succinyl (3-carboxypropanoyl) group to an acceptor molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a succinyl group to a nitrogen atom on the acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "N-succinyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "O-succinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a succinyl group to an oxygen atom on the acceptor molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a succinyl group to a sulfur atom on the acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "S-succinyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a sinapoyl group to an acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "sinapoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "O-sinapoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a sinapoyl group to an oxygen atom on the acceptor molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sinapoylglucose:malate sinapoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.92"^^xsd:string) "1-sinapoylglucose-L-malate sinapoyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sinapoylglucose-malate O-sinapoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.92"^^xsd:string) "1-O-sinapoyl-beta-D-glucose:(S)-malate O-sinapoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.92"^^xsd:string) Annotation( "RHEA:12628"^^xsd:string) "Catalysis of the reaction: (S)-malate + 1-O-sinapoyl-beta-D-glucose = D-glucose + sinapoyl (S)-malate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor)."^^xsd:string) AnnotationAssertion(rdfs:label "transferase activity, transferring amino-acyl groups"^^xsd:string) AnnotationAssertion( "aminoacyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.2.15"^^xsd:string) "phytochelatin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.15"^^xsd:string) "Catalysis of the reaction: glutathione + Glu(-Cys)(n)-Gly = Gly + Glu(-Cys)(n+1)-Gly."^^xsd:string) AnnotationAssertion(rdfs:label "glutathione gamma-glutamylcysteinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.15"^^xsd:string) "glutathione:poly(4-glutamyl-cysteinyl)glycine 4-glutamylcysteinyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.15"^^xsd:string) "gamma-glutamylcysteine dipeptidyl transpeptidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "transglycosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor)."^^xsd:string) AnnotationAssertion(rdfs:label "transferase activity, transferring glycosyl groups"^^xsd:string) AnnotationAssertion( "transferase activity, transferring other glycosyl groups"^^xsd:string) AnnotationAssertion( "transglycosylase activity"^^xsd:string) AnnotationAssertion( "glycosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "transferase activity, transferring hexosyl groups"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor)."^^xsd:string) AnnotationAssertion( "hexosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cellulose synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.29"^^xsd:string) "cellulose synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) Annotation( "EC:2.4.1.29"^^xsd:string) "Catalysis of the reaction: nucleoside-disphosphate-glucose + ((1,4)-beta-D-glucosyl)(n) = nucleoside-disphosphate + ((1,4)-beta-D-glucosyl)(n+1)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) "beta-1,4-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) "1,4-beta-glucan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) "UDPglucose-cellulose glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) "UDPglucose-beta-glucan glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cellulose synthase (UDP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) "UDP-glucose-1,4-beta-glucan glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) "Catalysis of the reaction: UDP-glucose + ((1,4)-beta-D-glucosyl)(n) = UDP + ((1,4)-beta-D-glucosyl)(n+1)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) "UDPglucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) "GS-I"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) "UDP-glucose-cellulose glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) "uridine diphosphoglucose-1,4-beta-glucan glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) "1,4-beta-D-glucan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) "glucan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) "beta-glucan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) "UDP-glucose-beta-D-glucan glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) "beta-1,4-glucan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) "UDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) "beta-1,4-glucan synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.12"^^xsd:string) "uridine diphosphoglucose-cellulose glucosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.29"^^xsd:string) "GDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.29"^^xsd:string) "guanosine diphosphoglucose-1,4-beta-glucan glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.29"^^xsd:string) "guanosine diphosphoglucose-cellulose glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.29"^^xsd:string) "cellulose synthase (guanosine diphosphate-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.29"^^xsd:string) "GDPglucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.29"^^xsd:string) "GDP-glucose-beta-D-glucan glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.29"^^xsd:string) "GDP-glucose-cellulose glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.29"^^xsd:string) "Catalysis of the reaction: GDP-glucose + ((1,4)-beta-D-glucosyl)(n) = GDP + ((1,4)-beta-D-glucosyl)(n+1)."^^xsd:string) AnnotationAssertion(rdfs:label "cellulose synthase (GDP-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "xyloglucan:xyloglucosyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.207"^^xsd:string) "xyloglucan:xyloglucan xyloglucanotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.207"^^xsd:string) "xyloglucan endotransglycosylase activity"^^xsd:string) AnnotationAssertion( "endoxyloglucan transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.207"^^xsd:string) "endo-xyloglucan transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.207"^^xsd:string) "Catalysis of the cleavage of a beta-(1->4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of an acceptor, which can be a xyloglucan or an oligosaccharide of xyloglucan."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "pentosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "transferase activity, transferring pentosyl groups"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor)."^^xsd:string) AnnotationAssertion(rdfs:label "transferase activity, transferring alkyl or aryl (other than methyl) groups"^^xsd:string) AnnotationAssertion( "transferase activity, transferring alkyl or aryl groups, other than methyl groups"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.32"^^xsd:string) "PSase activity"^^xsd:string) AnnotationAssertion(rdfs:label "geranylgeranyl-diphosphate geranylgeranyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.32"^^xsd:string) "prephytoene-diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.32"^^xsd:string) "geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.32"^^xsd:string) "phytoene synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.32"^^xsd:string) "Catalysis of the reaction: 2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.22"^^xsd:string) "Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + spermine."^^xsd:string) AnnotationAssertion(rdfs:label "spermine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.22"^^xsd:string) "spermidine aminopropyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.22"^^xsd:string) "spermine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.22"^^xsd:string) "S-adenosylmethioninamine:spermidine 3-aminopropyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "transferase activity, transferring other nitrogenous groups"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of a nitrogenous group from one compound (donor) to another (acceptor)."^^xsd:string) AnnotationAssertion(rdfs:label "transferase activity, transferring nitrogenous groups"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reversible transfer of an oxime group to an acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "oximinotransaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "transferase activity, transferring phosphorus-containing groups"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphotransferase activity, alcohol group as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a carboxyl group (acceptor)."^^xsd:string) AnnotationAssertion(rdfs:label "phosphotransferase activity, carboxyl group as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenous group (acceptor)."^^xsd:string) AnnotationAssertion(rdfs:label "phosphotransferase activity, nitrogenous group as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a phosphate group (acceptor)."^^xsd:string) AnnotationAssertion(rdfs:label "phosphotransferase activity, phosphate group as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "diphosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "http://www.chem.qmul.ac.uk/iubmb/enzyme/EC2/intro.html"^^xsd:string) "Catalysis of the transfer of a diphosphate group from one compound (donor) to a another (acceptor)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of a nucleotidyl group to a reactant."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphotransferase activity, for other substituted phosphate groups"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "http://www.chem.qmul.ac.uk/iubmb/enzyme/EC2/intro.html"^^xsd:string) "Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl residues, from one compound (donor) to a another (acceptor)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "http://www.chem.qmul.ac.uk/iubmb/enzyme/EC2/intro.html"^^xsd:string) "Catalysis of the transfer of two phosphate groups from a donor, such as ATP, to two different acceptors."^^xsd:string) AnnotationAssertion(rdfs:label "phosphotransferase activity, paired acceptors"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of a sulfur-containing group from one compound (donor) to another (acceptor)."^^xsd:string) AnnotationAssertion( "transferase activity, transferring sulphur-containing groups"^^xsd:string) AnnotationAssertion(rdfs:label "transferase activity, transferring sulfur-containing groups"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sulfurtransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "tRNA sulfurtransferase activity"^^xsd:string) AnnotationAssertion( "sulphurtransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0721662544"^^xsd:string) "Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-mercaptopyruvate sulfurtransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.2"^^xsd:string) "beta-mercaptopyruvate sulfurtransferase activity"^^xsd:string) AnnotationAssertion( "mercaptopyruvate sulfurtransferase activity"^^xsd:string) AnnotationAssertion( "3-mercaptopyruvate sulphurtransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.2"^^xsd:string) "Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.2"^^xsd:string) "3-mercaptopyruvate:cyanide sulfurtransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "transferase activity, transferring selenium-containing groups"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of a selenium-containing group from one compound (donor) to another (acceptor)."^^xsd:string) AnnotationAssertion( "selenotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3."^^xsd:string) AnnotationAssertion(rdfs:label "hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydrolase activity, acting on ester bonds"^^xsd:string) AnnotationAssertion( "esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the hydrolysis of any ester bond."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "thiolesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "http://www.onelook.com"^^xsd:string) "Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A."^^xsd:string) AnnotationAssertion(rdfs:label "thiolester hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.41"^^xsd:string) "K-pNPPase activity"^^xsd:string) AnnotationAssertion( "phosphatase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.41"^^xsd:string) "NPPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.41"^^xsd:string) "p-nitrophenylphosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion( "phosphoric monoester hydrolase activity"^^xsd:string) AnnotationAssertion( "4-nitrophenylphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.41"^^xsd:string) "p-nitrophenylphosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3"^^xsd:string) Annotation( "EC:3.1.3.41"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.41"^^xsd:string) "4-nitrophenylphosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.41"^^xsd:string) "para-nitrophenyl phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.41"^^xsd:string) "ecto-p-nitrophenyl phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.41"^^xsd:string) "nitrophenyl phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.41"^^xsd:string) "PNPPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "triphosphoric monoester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of a triphosphoester to give a triphosphate group and a free hydroxyl group."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of a diphosphoester to give a diphosphate group and a free hydroxyl group."^^xsd:string) AnnotationAssertion(rdfs:label "diphosphoric monoester hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.8"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Catalysis of the hydrolysis of a phosphoric triester."^^xsd:string) AnnotationAssertion(rdfs:label "phosphoric triester hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters."^^xsd:string) AnnotationAssertion( "exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5' phosphomonoesters"^^xsd:string) AnnotationAssertion(rdfs:label "exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters."^^xsd:string) AnnotationAssertion(rdfs:label "exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "N-glycosylase"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the hydrolysis of any glycosyl bond."^^xsd:string) AnnotationAssertion( "glycosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydrolase activity, acting on glycosyl bonds"^^xsd:string) AnnotationAssertion( "glycosylase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the hydrolysis of any N-glycosyl bond."^^xsd:string) AnnotationAssertion(rdfs:label "hydrolase activity, hydrolyzing N-glycosyl compounds"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydrolase activity, acting on ether bonds"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Catalysis of the hydrolysis of any ether or thioether bond, -O- or -S- respectively."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "thioether hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.1.-"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of a thioether bond, -S-."^^xsd:string) AnnotationAssertion( "trialkylsulphonium hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trialkylsulfonium hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.3.2.-"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of an ether bond, -O-."^^xsd:string) AnnotationAssertion(rdfs:label "ether hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "http://www.onelook.com"^^xsd:string) "Catalysis of the hydrolysis of a dipeptide."^^xsd:string) AnnotationAssertion(rdfs:label "dipeptidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CARBOXYPEPTIDASE"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) "Catalysis of the hydrolysis of C-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile."^^xsd:string) AnnotationAssertion(rdfs:label "cysteine-type carboxypeptidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds."^^xsd:string) AnnotationAssertion(rdfs:label "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"^^xsd:string) AnnotationAssertion( "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide."^^xsd:string) AnnotationAssertion(rdfs:label "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amide."^^xsd:string) AnnotationAssertion(rdfs:label "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "http://www.onelook.com/"^^xsd:string) "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a nitrile, a compound containing the cyano radical, -CN."^^xsd:string) AnnotationAssertion(rdfs:label "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the hydrolysis of any acid anhydride."^^xsd:string) AnnotationAssertion(rdfs:label "hydrolase activity, acting on acid anhydrides"^^xsd:string) AnnotationAssertion( "hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the hydrolysis of any acid anhydride which contains phosphorus."^^xsd:string) AnnotationAssertion(rdfs:label "hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides"^^xsd:string) AnnotationAssertion( "hydrolase activity, acting on acid anhydrides, in sulphonyl-containing anhydrides"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of any acid anhydride which contains a sulfonyl group, -SO2-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of an acid anhydride to directly drive the transport of a substance across a membrane."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydrolase activity, acting on acid carbon-carbon bonds"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the hydrolysis of any acid carbon-carbon bond."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of any acid carbon-carbon bond in a ketonic substance, a substance containing a keto (C=O) group."^^xsd:string) AnnotationAssertion(rdfs:label "hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydrolase activity, acting on acid halide bonds"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the hydrolysis of any acid halide bond."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the hydrolysis of any acid phosphorus-nitrogen bond."^^xsd:string) AnnotationAssertion(rdfs:label "hydrolase activity, acting on acid phosphorus-nitrogen bonds"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydrolase activity, acting on acid sulfur-nitrogen bonds"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the hydrolysis of any acid sulfur-nitrogen bond."^^xsd:string) AnnotationAssertion( "hydrolase activity, acting on acid sulphur-nitrogen bonds"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the hydrolysis of any acid carbon-phosphorus bond."^^xsd:string) AnnotationAssertion(rdfs:label "hydrolase activity, acting on acid carbon-phosphorus bonds"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "hydrolase activity, acting on acid sulphur-sulphur bonds"^^xsd:string) AnnotationAssertion(rdfs:label "hydrolase activity, acting on acid sulfur-sulfur bonds"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the hydrolysis of any acid sulfur-sulfur bond."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.-.-.-"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring."^^xsd:string) AnnotationAssertion( "other lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond."^^xsd:string) AnnotationAssertion( "other carbon-carbon lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "carbon-carbon lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "http://www.mercksource.com/"^^xsd:string) "Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound."^^xsd:string) AnnotationAssertion(rdfs:label "carboxy-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "http://www.mercksource.com/"^^xsd:string) "Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone."^^xsd:string) AnnotationAssertion( "aldolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aldehyde-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Catalysis of the cleavage of a C-C bond by other means than by hydrolysis or oxidation, of a 3-hydroxy acid."^^xsd:string) AnnotationAssertion(rdfs:label "oxo-acid-lyase activity"^^xsd:string) AnnotationAssertion( "oxo-acid lyase activity"^^xsd:string) AnnotationAssertion( "oxoacid lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "other carbon-oxygen lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.-.-"^^xsd:string) "Catalysis of the breakage of a carbon-oxygen bond."^^xsd:string) AnnotationAssertion(rdfs:label "carbon-oxygen lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1"^^xsd:string) "Catalysis of the cleavage of a carbon-oxygen bond by elimination of water."^^xsd:string) AnnotationAssertion(rdfs:label "hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carbon-oxygen lyase activity, acting on polysaccharides"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.-.-"^^xsd:string) "Catalysis of the cleavage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.-.-"^^xsd:string) "Catalysis of the cleavage of a carbon-oxygen bond by elimination of a phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "carbon-oxygen lyase activity, acting on phosphates"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carbon-nitrogen lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.-.-"^^xsd:string) "Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99)."^^xsd:string) AnnotationAssertion( "other carbon-nitrogen lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.-.-"^^xsd:string) Annotation( "GOC:krc"^^xsd:string) "Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.-.-"^^xsd:string) Annotation( "GOC:krc"^^xsd:string) "Catalysis of the release of amides or amidines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amide or amidine as a substrate."^^xsd:string) AnnotationAssertion(rdfs:label "amidine-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "amine-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.-.-"^^xsd:string) Annotation( "GOC:krc"^^xsd:string) "Catalysis of the release of amides by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amine as a substrate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "strictosidine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.3.2"^^xsd:string) Annotation( "RHEA:15016"^^xsd:string) "Catalysis of the reaction: 3alpha(S)-strictosidine + H(2)O = secologanin + tryptamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.3.2"^^xsd:string) "3-alpha(S)-strictosidine tryptamine-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.3.2"^^xsd:string) "strictosidine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.3.2"^^xsd:string) "3-alpha(S)-strictosidine tryptamine-lyase (secologanin-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.3.2"^^xsd:string) "STR activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "carbon-sulphur lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "carbon-sulfur lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.-.-"^^xsd:string) "Catalysis of the elimination of hydrogen sulfide or substituted H2S."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11470512"^^xsd:string) "L-vinylglycine deaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-aminocyclopropane-1-carboxylate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.14"^^xsd:string) Annotation( "RHEA:21747"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) = 1-aminocyclopropane-1-carboxylate + S-methyl-5'-thioadenosine + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.14"^^xsd:string) "aminocyclopropanecarboxylic acid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.14"^^xsd:string) "1-aminocyclopropane-1-carboxylate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.14"^^xsd:string) "aminocyclopropanecarboxylate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.14"^^xsd:string) "S-adenosyl-L-methionine methylthioadenosine-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.14"^^xsd:string) "1-aminocyclopropane-1-carboxylic acid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.14"^^xsd:string) "1-aminocyclopropanecarboxylate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.14"^^xsd:string) "S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.14"^^xsd:string) "ACC synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11470512"^^xsd:string) "L-VG deaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carbon-halide lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the breakage of a bond between carbon and any halogen atom."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond."^^xsd:string) AnnotationAssertion(rdfs:label "phosphorus-oxygen lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.6.1.1"^^xsd:string) "magnesium-protoporphyrin IX chelatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.6.1.1"^^xsd:string) "magnesium-protoporphyrin chelatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.6.1.1"^^xsd:string) "Mg-protoporphyrin IX chelatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "magnesium chelatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.6.1.1"^^xsd:string) "protoporphyrin IX magnesium-chelatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.6.1.1"^^xsd:string) Annotation( "RHEA:13964"^^xsd:string) "Catalysis of the reaction: ATP + H(2)O + Mg(2+) + protoporphyrin IX = ADP + 2 H(+) + magnesium protoporphyrin IX + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.6.1.1"^^xsd:string) "Mg-protoporphyrin IX magnesium-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.6.1.1"^^xsd:string) "magnesium-chelatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.6.1.1"^^xsd:string) "Mg-chelatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.6.1.1"^^xsd:string) "Mg-protoporphyrin IX magnesio-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.6.1.1"^^xsd:string) "protoporphyrin IX Mg-chelatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "anaerobic cobalt chelatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.3"^^xsd:string) "Catalysis of the reaction: sirohydrochlorin + Co2+ = cobalt-sirohydrochlorin + 2 H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.3"^^xsd:string) "CbiXS"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.3"^^xsd:string) "sirohydrochlorin cobalt-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.3"^^xsd:string) "CbiX"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.3"^^xsd:string) "cobalt-sirohydrochlorin cobalt-lyase (sirohydrochlorin-forming)"^^xsd:string) AnnotationAssertion( "CbiK"^^xsd:string) AnnotationAssertion(rdfs:label "sirohydrochlorin cobaltochelatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "other isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "racemase and epimerase activity, acting on other compounds"^^xsd:string) AnnotationAssertion(rdfs:label "racemase and epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of a reaction that alters the configuration of one or more chiral centers in an amino acid."^^xsd:string) AnnotationAssertion(rdfs:label "racemase and epimerase activity, acting on amino acids and derivatives"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "racemase and epimerase activity, acting on hydroxy acids and derivatives"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of a reaction that alters the configuration of one or more chiral centers in a hydroxy acid molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of a reaction that alters the configuration of one or more chiral centers in a carbohydrate molecule."^^xsd:string) AnnotationAssertion(rdfs:label "racemase and epimerase activity, acting on carbohydrates and derivatives"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers."^^xsd:string) AnnotationAssertion(rdfs:label "cis-trans isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "intramolecular oxidoreductase activity, other intramolecular oxidoreductases"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.-.-"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, and no oxidized product appears."^^xsd:string) AnnotationAssertion( "intramolecular isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "intramolecular oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "intramolecular oxidoreductase activity, interconverting aldoses and ketoses"^^xsd:string) AnnotationAssertion( "intramolecular isomerase activity, interconverting aldoses and ketoses"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is an aldose or a ketose, are the same molecule, and no oxidized product appears."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "intramolecular isomerase activity, interconverting keto- and enol-groups"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is a keto- or an enol-group, are the same molecule, and no oxidized product appears."^^xsd:string) AnnotationAssertion(rdfs:label "intramolecular oxidoreductase activity, interconverting keto- and enol-groups"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "intramolecular oxidoreductase activity, transposing C=C bonds"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more carbon-carbon double bonds in the molecule are rearranged, and no oxidized product appears."^^xsd:string) AnnotationAssertion( "intramolecular isomerase activity, transposing C=C bonds"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.4"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more sulfur-sulfur bonds in the molecule are rearranged, and no oxidized product appears."^^xsd:string) AnnotationAssertion( "intramolecular isomerase activity, transposing S-S bonds"^^xsd:string) AnnotationAssertion(rdfs:label "intramolecular oxidoreductase activity, transposing S-S bonds"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "intramolecular transferase activity"^^xsd:string) AnnotationAssertion( "intramolecular transferase activity, transferring other groups"^^xsd:string) AnnotationAssertion( "mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a functional group from one position to another within a single molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "intramolecular transferase activity, transferring acyl groups"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of an acyl group from one position to another within a single molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phosphomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a phosphate group from one position to another within a single molecule."^^xsd:string) AnnotationAssertion( "phosphotransferase activity, with regeneration of donors, apparently catalyzing intramolecular transfers"^^xsd:string) AnnotationAssertion(rdfs:label "intramolecular transferase activity, phosphotransferases"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of an amino group from one position to another within a single molecule."^^xsd:string) AnnotationAssertion(rdfs:label "intramolecular transferase activity, transferring amino groups"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.99.8"^^xsd:string) "squalene-2,3-epoxide-cycloartenol cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.8"^^xsd:string) "2,3-epoxysqualene--cycloartenol cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.8"^^xsd:string) "(S)-2,3-epoxysqualene mutase (cyclizing, cycloartenol-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.8"^^xsd:string) "2,3-epoxysqualene cycloartenol-cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.8"^^xsd:string) Annotation( "RHEA:21311"^^xsd:string) "Catalysis of the reaction: (S)-2,3-epoxysqualene = cycloartenol."^^xsd:string) AnnotationAssertion(Annotation( "PMID:18033581"^^xsd:string) "oxidosqualene:cycloartenol cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.8"^^xsd:string) "2,3-oxidosqualene-cycloartenol cyclase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cycloartenol synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "http://www.mercksource.com/"^^xsd:string) "The catalysis of certain rearrangements of a molecule to break or form a ring."^^xsd:string) AnnotationAssertion(rdfs:label "intramolecular lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jh2"^^xsd:string) "synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ligase activity, forming carbon-oxygen bonds"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the joining of two molecules via a carbon-oxygen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the joining of an amino acid and a nucleic acid (usually tRNA) or poly(ribitol phosphate), with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. The reaction forms an aminoacyl-tRNA or a related compound."^^xsd:string) AnnotationAssertion(rdfs:label "ligase activity, forming aminoacyl-tRNA and related compounds"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ligase activity, forming carbon-sulfur bonds"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."^^xsd:string) AnnotationAssertion( "ligase activity, forming carbon-sulphur bonds"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "acid-thiol ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "other carbon-nitrogen ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ligase activity, forming carbon-nitrogen bonds"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the ligation of an acid to ammonia (NH3) or an amide via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."^^xsd:string) AnnotationAssertion( "amide synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acid-ammonia (or amide) ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."^^xsd:string) AnnotationAssertion( "peptide synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acid-amino acid ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclo-ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.1"^^xsd:string) Annotation( "EC:6.3.3.2"^^xsd:string) Annotation( "EC:6.3.3.4"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the joining of two groups within a single molecule via a carbon-nitrogen bond, forming heterocyclic ring, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carbon-nitrogen ligase activity, with glutamine as amido-N-donor"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12360532"^^xsd:string) "Catalysis of the transfer of the amide nitrogen of glutamine to a variety of substrates. GATases catalyze two separate reactions at two active sites, which are located either on a single polypeptide chain or on different subunits. In the glutaminase reaction, glutamine is hydrolyzed to glutamate and ammonia, which is added to an acceptor substrate in the synthase reaction."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.4"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the joining of two molecules via a carbon-carbon bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "ligase activity, forming carbon-carbon bonds"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.5"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the joining of two molecules, or two groups within a single molecule, via a phosphoric ester bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "ligase activity, forming phosphoric ester bonds"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) "adenosine triphosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) "ATP monophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) "adenosine 5'-triphosphatase activity"^^xsd:string) AnnotationAssertion( "adenosinetriphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) "SV40 T-antigen"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) "(Ca2+ + Mg2+)-ATPase"^^xsd:string) AnnotationAssertion( "ATP phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) "HCO3--ATPase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) "complex V (mitochondrial electron transport)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) "ATP hydrolase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "endodeoxyribonuclease activity, producing 5'-phosphomonoesters"^^xsd:string) AnnotationAssertion( "endodeoxyribonuclease activity, producing 5' phosphomonoesters"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters."^^xsd:string) AnnotationAssertion(rdfs:label "endodeoxyribonuclease activity, producing 3'-phosphomonoesters"^^xsd:string) AnnotationAssertion( "endodeoxyribonuclease activity, producing other than 5'-phosphomonoesters"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the hydrolysis of ester linkages at specific sites within a deoxyribonucleic acid molecule by creating internal breaks."^^xsd:string) AnnotationAssertion(rdfs:label "site-specific endodeoxyribonuclease activity, specific for altered base"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "endoribonuclease activity, producing 5'-phosphomonoesters"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "endoribonuclease activity, producing 3'-phosphomonoesters"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters."^^xsd:string) AnnotationAssertion( "endoribonuclease activity, producing other than 5'-phosphomonoesters"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "5'-endonuclease activity"^^xsd:string) AnnotationAssertion(rdfs:label "endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters"^^xsd:string) AnnotationAssertion( "endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3'-endonuclease activity"^^xsd:string) AnnotationAssertion( "endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 3'-phosphomonoesters."^^xsd:string) AnnotationAssertion(rdfs:label "endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters."^^xsd:string) AnnotationAssertion(rdfs:label "exodeoxyribonuclease activity, producing 5'-phosphomonoesters"^^xsd:string) AnnotationAssertion( "exonuclease VIII activity"^^xsd:string) AnnotationAssertion( "exodeoxyribonuclease activity, producing 5' phosphomonoesters"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "exoribonuclease activity, producing 5' phosphomonoesters"^^xsd:string) AnnotationAssertion(rdfs:label "exoribonuclease activity, producing 5'-phosphomonoesters"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters."^^xsd:string) AnnotationAssertion(rdfs:label "exoribonuclease activity, producing 3'-phosphomonoesters"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a cytochrome molecule."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an oxygen molecule."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "oxidoreductase activity, acting on the CH-OH group of donors, disulphide as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a disulfide molecule."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the aldehyde or oxo group of donors"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.7"^^xsd:string) "MIHC kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.7"^^xsd:string) "ATP:myosin-heavy-chain O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.7"^^xsd:string) "Catalysis of the reaction: ATP + myosin-heavy-chain = ADP + myosin-heavy-chain phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.7"^^xsd:string) "myosin heavy chain kinase A activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.7"^^xsd:string) "myosin-heavy-chain kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.7"^^xsd:string) "MHCK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.7"^^xsd:string) "myosin II heavy chain kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.7"^^xsd:string) "myosin II heavy-chain kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.7"^^xsd:string) "myosin I heavy chain kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.7"^^xsd:string) "ATP:myosin heavy-chain O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.7"^^xsd:string) "STK6"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.7"^^xsd:string) "myosin I heavy-chain kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.7"^^xsd:string) "myosin heavy-chain kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.7"^^xsd:string) "calmodulin-dependent myosin heavy chain kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "myosin heavy chain kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sterol 3-beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "UDPG:sterol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.173"^^xsd:string) "uridine diphosphoglucose-poriferasterol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.173"^^xsd:string) "UDP-glucose:sterol 3-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.173"^^xsd:string) "sterol-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.173"^^xsd:string) "UDPG-SGTase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.173"^^xsd:string) "uridine diphosphoglucose-sterol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.173"^^xsd:string) "UDPglucose:sterol 3-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.173"^^xsd:string) "sterol 3beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.173"^^xsd:string) "UDP-glucose-sterol beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.173"^^xsd:string) "UDP-glucose-sterol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.173"^^xsd:string) "Catalysis of the reaction: UDP-glucose + a sterol = UDP + an O-glucosylsterol."^^xsd:string) AnnotationAssertion( "sterol glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "sterol:UDPG glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "UDP-glucose:sterol glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "G-protein coupled acetylcholine receptor activity"^^xsd:string) AnnotationAssertion( "G-protein-coupled acetylcholine receptor activity"^^xsd:string) AnnotationAssertion( "muscarinic acetylcholine receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:fj"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "acetylcholine receptor activity, G-protein coupled"^^xsd:string) AnnotationAssertion( "G protein coupled acetylcholine receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "SAPK"^^xsd:string) AnnotationAssertion( "stress-activated protein kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "SAP kinase activity"^^xsd:string) AnnotationAssertion( "stress-activated kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ma"^^xsd:string) "Catalysis of the phosphorylation of proteins. A family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. Strongly activated by stress signals such as heat or osmotic shock, DNA-damaging agents, inhibitors of protein synthesis and pro-inflammatory cytokines."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "follicle stimulating hormone activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198547684"^^xsd:string) "The action characteristic of follicle-stimulating hormone (FSH), a gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland. Upon receptor binding, FSH stimulates growth of Graafian follicles in the ovaries in females, and stimulates the epithelium of the seminiferous tubules to increase spermatogenesis."^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "follitropin activity"^^xsd:string) AnnotationAssertion(rdfs:label "follicle-stimulating hormone activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "FSH activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "gamma-aminobutyric acid binding"^^xsd:string) AnnotationAssertion( "4-aminobutyrate receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:10637650"^^xsd:string) "Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms."^^xsd:string) AnnotationAssertion( "GABA binding"^^xsd:string) AnnotationAssertion( "gamma-aminobutyrate binding"^^xsd:string) AnnotationAssertion( "gamma-aminobutyric acid receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "GABA receptor activity"^^xsd:string) AnnotationAssertion( "4-aminobutanoate receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "violet-sensitive opsin"^^xsd:string) AnnotationAssertion( "blue-sensitive opsin"^^xsd:string) AnnotationAssertion( "vitamin A binding"^^xsd:string) AnnotationAssertion( "long-wave-sensitive opsin"^^xsd:string) AnnotationAssertion( "short-wave-sensitive opsin"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15035"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with retinal, one of the forms of vitamin A. Retinal plays an important role in the visual process in most vertebrates, combining with opsins to form visual pigments in the retina."^^xsd:string) AnnotationAssertion( "red-sensitive opsin"^^xsd:string) AnnotationAssertion( "UV-sensitive opsin"^^xsd:string) AnnotationAssertion( "opsin"^^xsd:string) AnnotationAssertion( "retinaldehyde binding"^^xsd:string) AnnotationAssertion(rdfs:label "retinal binding"^^xsd:string) AnnotationAssertion( "green-sensitive opsin"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.4.19.3"^^xsd:string) Annotation( "EC:3.4.19.6"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the release of the N-terminal pyroglutamyl group from a peptide or protein."^^xsd:string) AnnotationAssertion(rdfs:label "pyroglutamyl-peptidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ligand-dependent nuclear receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:7776974"^^xsd:string) "Interacting selectively and non-covalently, in a ligand dependent manner, with a nuclear receptor protein."^^xsd:string) AnnotationAssertion( "ligand-dependent nuclear receptor interactor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "SUMO-specific protease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rn"^^xsd:string) Annotation( "PMID:10094048"^^xsd:string) Annotation( "PMID:11031248"^^xsd:string) Annotation( "PMID:11265250"^^xsd:string) "Catalysis of the hydrolysis of SUMO, a small ubiquitin-related modifier, from previously sumoylated substrates."^^xsd:string) AnnotationAssertion( "ULP"^^xsd:string) AnnotationAssertion( "SUSP"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion( "glycine receptor"^^xsd:string) AnnotationAssertion(rdfs:label "extracellular-glycine-gated ion channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glycine-inhibited chloride channel activity"^^xsd:string) AnnotationAssertion(rdfs:label "extracellular-glycine-gated chloride channel activity"^^xsd:string) AnnotationAssertion( "glycine receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "galactoside binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:24163"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with any glycoside in which the sugar group is galactose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "short-branched-chain-acyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a short branched chain fatty acid residue."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "natriuretic peptide receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with a natriuretic peptide and transmitting the signal to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-2 macroglobulin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:ma"^^xsd:string) Annotation( "PMID:6188403"^^xsd:string) "Combining with alpha-2 macroglobulin and delivering alpha-2 macroglobulin into the cell via receptor-mediated endocytosis."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "P450nor"^^xsd:string) AnnotationAssertion( "CYP55"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.5"^^xsd:string) "nitrous-oxide:acceptor oxidoreductase (NO-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "nitric oxide reductase activity"^^xsd:string) AnnotationAssertion( "cytochrome bc nitric oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.5"^^xsd:string) "Catalysis of the reaction: H(2)O + 2 ferricytochrome c + nitrous oxide = 2 H(+) + 2 ferrocytochrome c + 2 nitric oxide."^^xsd:string) AnnotationAssertion( "P450 nitric oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.5"^^xsd:string) "nitrogen oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.5"^^xsd:string) "nitric-oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.5"^^xsd:string) "nitrous-oxide:(acceptor) oxidoreductase (NO-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10899311"^^xsd:string) "Catalysis of the formation of disulfide bridges."^^xsd:string) AnnotationAssertion(rdfs:label "flavin-linked sulfhydryl oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.3.2"^^xsd:string) "thiol:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.3.2"^^xsd:string) "Catalysis of the reaction: 4 R'C(R)SH + O2 = 2 R'C(R)S-S(R)CR' + 2 H2O."^^xsd:string) AnnotationAssertion(rdfs:label "thiol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.3.2"^^xsd:string) "sulfhydryl oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.132"^^xsd:string) "chitosan N-acetylglucosaminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.132"^^xsd:string) "Catalysis of the endohydrolysis of beta-1,4-linkages between N-acetyl-D-glucosamine and D-glucosamine residues in a partly acetylated chitosan."^^xsd:string) AnnotationAssertion(rdfs:label "chitosanase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "lipoate-protein ligase A activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.-"^^xsd:string) "Catalysis of the formation of carbon-nitrogen bonds between lipoate (5-(1,2-dithiolan-3-yl)pentanoate) and a protein."^^xsd:string) AnnotationAssertion( "lipoate-protein ligase B activity"^^xsd:string) AnnotationAssertion(rdfs:label "lipoate-protein ligase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.3"^^xsd:string) Annotation( "RHEA:22459"^^xsd:string) "Catalysis of the reaction: creatine + H(2)O = sarcosine + urea."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.3"^^xsd:string) "creatine amidinohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "creatinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.39"^^xsd:string) "ribulose bisphosphate carboxylase/oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.39"^^xsd:string) "3-phospho-D-glycerate carboxy-lyase (dimerizing; D-ribulose-1,5-bisphosphate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.39"^^xsd:string) "diphosphoribulose carboxylase activity"^^xsd:string) AnnotationAssertion( "rubisco activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.39"^^xsd:string) "carboxydismutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.39"^^xsd:string) "RuBP carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.39"^^xsd:string) "RuBisCO activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.39"^^xsd:string) "ribulose 1,5-diphosphate carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.39"^^xsd:string) "ribulose 1,5-diphosphate carboxylase/oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.39"^^xsd:string) "ribulose 1,5-bisphosphate carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.39"^^xsd:string) "D-ribulose-1,5-bisphosphate carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.39"^^xsd:string) "ribulose diphosphate carboxylase/oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.39"^^xsd:string) "3-phospho-D-glycerate carboxy-lyase (dimerizing)"^^xsd:string) AnnotationAssertion(rdfs:label "ribulose-bisphosphate carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.39"^^xsd:string) "ribulose diphosphate carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.39"^^xsd:string) "D-ribulose 1,5-diphosphate carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.39"^^xsd:string) "Catalysis of the reaction: D-ribulose 1,5-bisphosphate + CO2 + H2O = 2 3-phospho-D-glycerate."^^xsd:string) AnnotationAssertion( "ribulose 1,5-bisphosphate carboxylase/oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.78"^^xsd:string) "endo-1,4-mannanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.78"^^xsd:string) "endo-beta-1,4-mannase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.78"^^xsd:string) "endo-beta-mannanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.78"^^xsd:string) "1,4-beta-D-mannan mannanohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannan endo-1,4-beta-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.78"^^xsd:string) "beta-1,4-mannan 4-mannanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.78"^^xsd:string) "beta-D-mannanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.78"^^xsd:string) "beta-mannanase B"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.78"^^xsd:string) "endo-1,4-beta-mannanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.78"^^xsd:string) "Catalysis of the random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans, glucomannans, and galactoglucomannans."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.78"^^xsd:string) "beta-mannanase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sigma transcription factor"^^xsd:string) AnnotationAssertion(rdfs:label "sigma factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "GOC:txnOH"^^xsd:string) "A sigma factor is the promoter specificity subunit of eubacterial-type multisubunit RNA polymerases, those whose core subunit composition is often described as alpha(2)-beta-beta-prime. (This type of multisubunit RNA polymerase complex is known to be found in eubacteria and plant plastids). Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, this binds specifically to promoter sequences, with the sigma factor making sequence specific contacts with the promoter elements. The sigma subunit is released from the elongating form of the polymerase and is thus free to act catalytically for multiple RNA polymerase core enzymes."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:txnOH"^^xsd:string) Annotation( "Wikipedia:Anti-sigma_factors"^^xsd:string) "The function of binding to a sigma factor and stopping, preventing or reducing the rate of its transcriptional activity."^^xsd:string) AnnotationAssertion( "anti-sigma factor activity"^^xsd:string) AnnotationAssertion(rdfs:label "sigma factor antagonist activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.6"^^xsd:string) "arginine dihydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arginine deiminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.6"^^xsd:string) "L-arginine iminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.6"^^xsd:string) "Catalysis of the reaction: L-arginine + H2O = L-citrulline + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.6"^^xsd:string) "citrulline iminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.6"^^xsd:string) "L-arginine deiminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.1.8"^^xsd:string) "LS"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.8"^^xsd:string) "protein 6-N-(octanoyl)lysine:sulfur sulfurtransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.8"^^xsd:string) "LipA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "lipoic acid synthase"^^xsd:string) AnnotationAssertion(rdfs:label "lipoate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.8"^^xsd:string) "protein N6-(octanoyl)lysine:sulfur sulfurtransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.8"^^xsd:string) "lipoyl synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.8"^^xsd:string) Annotation( "PMID:18307109"^^xsd:string) "Catalysis of the reaction: protein N6-(octanoyl)lysine + 2 sulfur + 2 S-adenosyl-L-methionine = protein N6-(lipoyl)lysine + 2 L-methionine + 2 5'-deoxyadenosyl."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.1.2"^^xsd:string) "precorrin-8X 11,12-methylmutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.1.2"^^xsd:string) "hydrogenobyrinic acid-binding protein activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.1.2"^^xsd:string) "Catalysis of the reaction: precorrin-8X = hydrogenobyrinate."^^xsd:string) AnnotationAssertion(rdfs:label "precorrin-8X methylmutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.1.2"^^xsd:string) "precorrin isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.1.2"^^xsd:string) "HBA synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.54"^^xsd:string) "precorrin-6B:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.54"^^xsd:string) "precorrin-6Y:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "precorrin-6A reductase activity"^^xsd:string) AnnotationAssertion( "precorrin-6X reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.54"^^xsd:string) "precorrin-6Y:NADP(+) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.54"^^xsd:string) "Catalysis of the reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.6"^^xsd:string) "cholesterol-O2 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.6"^^xsd:string) "cholesterol:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.6"^^xsd:string) "3beta-hydroxy steroid oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.6"^^xsd:string) "cholesterol-O(2) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.6"^^xsd:string) Annotation( "RHEA:21331"^^xsd:string) "Catalysis of the reaction: cholesterol + O2 = cholest-5-en-3-one + H2O2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.6"^^xsd:string) "cholesterol- O2 oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cholesterol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.6"^^xsd:string) "3beta-hydroxysteroid:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.129"^^xsd:string) "endoneuraminidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "endo-alpha-(2,8)-sialidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.129"^^xsd:string) "Catalysis of the endohydrolysis of (2->8)-alpha-sialosyl linkages in oligo- or poly(sialic) acids."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.129"^^xsd:string) "endo-N-acylneuraminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.129"^^xsd:string) "alpha-2,8-sialosylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.129"^^xsd:string) "poly(alpha-2,8-sialosyl) endo-N-acetylneuraminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.129"^^xsd:string) "poly(alpha-2,8-sialoside) alpha-2,8-sialosylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.129"^^xsd:string) "endo-N-acetylneuraminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.129"^^xsd:string) "endosialidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.129"^^xsd:string) "polysialoside (2->8)-alpha-sialosylhydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-sialidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of alpha-glycosidic linkages in oligo- or poly(sialic) acids."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "activin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Combining with activin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Activin is one of two gonadal glycoproteins related to transforming growth factor beta."^^xsd:string) AnnotationAssertion(rdfs:label "activin-activated receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10521354"^^xsd:string) Annotation( "PMID:16751265"^^xsd:string) "Catalysis of the hydrolysis of 3'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA."^^xsd:string) AnnotationAssertion(rdfs:label "3'-tyrosyl-DNA phosphodiesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Ras interactor activity"^^xsd:string) AnnotationAssertion(rdfs:label "Ras GTPase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with any member of the Ras superfamily of monomeric GTPases."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12184814"^^xsd:string) "Catalysis of the reaction: MAP kinase serine/threonine/tyrosine phosphate + H2O = MAP kinase serine/threonine/tyrosine + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase tyrosine/serine/threonine phosphatase activity"^^xsd:string) AnnotationAssertion( "dual-specificity MAP kinase phosphatase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "myosin phosphatase myosin binding"^^xsd:string) AnnotationAssertion(rdfs:label "myosin phosphatase activity"^^xsd:string) AnnotationAssertion( "myosin phosphatase, intrinsic catalyst activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) "Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "myosin phosphatase regulator activity"^^xsd:string) AnnotationAssertion( "myosin phosphatase, intrinsic regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.16"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Modulation of the activity of the enzyme myosin phosphatase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "myosin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html"^^xsd:string) "Interacting selectively and non-covalently with any part of a myosin complex; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments."^^xsd:string) AnnotationAssertion( "myosin phosphatase myosin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "myosin I binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html"^^xsd:string) "Interacting selectively and non-covalently with a class I myosin; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:16858867"^^xsd:string) Annotation( "http://www.mblab.gla.ac.uk/"^^xsd:string) "Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs)."^^xsd:string) AnnotationAssertion(rdfs:label "TBP-class protein binding"^^xsd:string) AnnotationAssertion( "TBP-related factor (TRF) protein binding"^^xsd:string) AnnotationAssertion( "TATA-binding protein binding"^^xsd:string) AnnotationAssertion( "TBP binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "potassium:amino acid symporter activity"^^xsd:string) AnnotationAssertion( "potassium:amino acid transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + K+(out) = amino acid(in) + K+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Rap guanyl-nucleotide exchange factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rap family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ceramidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.23"^^xsd:string) "acylsphingosine deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.23"^^xsd:string) "glycosphingolipid ceramide deacylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.23"^^xsd:string) "N-acylsphingosine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.23"^^xsd:string) "Catalysis of the reaction: N-acylsphingosine + H2O = a fatty acid + sphingosine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.47"^^xsd:string) "D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine galactohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.47"^^xsd:string) "trihexosyl ceramide galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.47"^^xsd:string) "Catalysis of the reaction: D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine + H2O = lactosyl-N-acylsphingosine + D-galactose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.47"^^xsd:string) "ceramidetrihexosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.47"^^xsd:string) "trihexosylceramide alpha-galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.47"^^xsd:string) "ceramidetrihexoside alpha-galactosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactosylgalactosylglucosylceramidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.47"^^xsd:string) "ceramide trihexosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.62"^^xsd:string) "glycosyl ceramide glycosylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.62"^^xsd:string) "phloridzin glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.62"^^xsd:string) "Catalysis of the reaction: glycosyl-N-acylsphingosine + H2O = a sugar + N-acylsphingosine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.62"^^xsd:string) "phloretin-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.62"^^xsd:string) "cerebrosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.62"^^xsd:string) "phloridzin beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.62"^^xsd:string) "glycosyl-N-acylsphingosine glycohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.62"^^xsd:string) "phlorizin hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.62"^^xsd:string) "lactase-phlorizin hydrolase"^^xsd:string) AnnotationAssertion(rdfs:label "glycosylceramidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "melanocyte stimulating hormone activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "alpha-melanocyte stimulating hormone activity"^^xsd:string) AnnotationAssertion(rdfs:label "melanocyte-stimulating hormone activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "alpha-melanophore stimulating hormone activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "The action characteristic of melanocyte-stimulating hormone, any of three peptide hormones that are produced by the intermediate lobe of the pituitary gland and, upon receptor binding, cause dispersal of melanosomes in melanophores of poikilothermic vertebrates."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "corticotropin-releasing hormone activity"^^xsd:string) AnnotationAssertion( "adrenocorticotropin-releasing hormone"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "The action characteristic of corticotropin-releasing hormone (CRH), any of a number of peptides released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, CRH increases the rate of corticotropin secretion by the anterior pituitary."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "polypeptide hormone binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with any peptide with hormonal activity in animals."^^xsd:string) AnnotationAssertion(rdfs:label "peptide hormone binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198547684"^^xsd:string) Annotation( "PMID:12581856"^^xsd:string) "Interacting selectively and non-covalently with Rho protein, any member of the Rho subfamily of the Ras superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton."^^xsd:string) AnnotationAssertion( "Rhophilin"^^xsd:string) AnnotationAssertion( "Rho interactor activity"^^xsd:string) AnnotationAssertion(rdfs:label "Rho GTPase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the GTP-bound form of the Rho protein."^^xsd:string) AnnotationAssertion(rdfs:label "GTP-Rho binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sphingosine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN3DJ-11417"^^xsd:string) "Catalysis of the reaction: sphingosine + ATP = sphingosine 1-phosphate + ADP."^^xsd:string) AnnotationAssertion(rdfs:label "D-erythro-sphingosine kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "retinol dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9857081"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + retinol = adenosine 3',5'-bisphosphate + anhydroretinol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "structural constituent of nuclear pore"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "The action of a molecule that contributes to the structural integrity of the nuclear pore complex."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.31"^^xsd:string) Annotation( "RHEA:12559"^^xsd:string) "Catalysis of the reaction: 6-O-phosphono-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.31"^^xsd:string) "6-PGL"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.31"^^xsd:string) "6-phospho-D-glucono-1,5-lactone lactonohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "6-phosphogluconolactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.31"^^xsd:string) "phosphogluconolactonase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with a FH1 domain of a protein, a proline-rich domain, usually located in front of a FH2 domain."^^xsd:string) AnnotationAssertion(rdfs:label "FH1 domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "guanosine diphosphofucose-beta-acetylglucosaminylsaccharide 4-alpha-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "blood group Lewis alpha-4-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "FucT-II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "3-alpha-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "guanosine diphosphofucose-glycoprotein 4-alpha-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "alpha-(1->4)-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "GDP-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "Lewis(Le) blood group gene-dependent alpha-(1->3/4)-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "beta-acetylglucosaminylsaccharide fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "blood-group substance Lea-dependent fucosyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "Lewis blood group alpha-(1,3/4)-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "GDP-beta-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "alpha-4-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion( "Lewis(Le) blood group gene-dependent alpha-(1,3/4)-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "Lewis FT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "blood-group substance Le(a)-dependent fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "Lewis alpha-(1,3/4)-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "(Lea)-dependent (alpha-3/4)-fucosyltransferase activity"^^xsd:string) AnnotationAssertion( "galactoside 3(4)-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "alpha-(1,4)-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-(1,3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1,3)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "(Le(a))-dependent (alpha-3/4)-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "alpha-(1,3/1,4) fucosyltransferase III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "guanosine diphosphofucose-glycoprotein 4-alpha-fucosyltransferase activity"^^xsd:string) AnnotationAssertion( "alpha(1,4)-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "Lewis alpha-(1->3/4)-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.65"^^xsd:string) "Lewis blood group alpha-(1->3/4)-fucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "5'-methylthioadenosine phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.28"^^xsd:string) "5'-deoxy-5'-methylthioadenosine phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.28"^^xsd:string) "MTA phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.28"^^xsd:string) "methylthioadenosine nucleoside phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.28"^^xsd:string) "S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.28"^^xsd:string) "Catalysis of the reaction: 5'-methylthioadenosine + phosphate = adenine + 5-methylthio-D-ribose 1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.28"^^xsd:string) "5'-methylthioadenosine:phosphate methylthio-D-ribosyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.28"^^xsd:string) "methylthioadenosine phosphorylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "S-methyl-5-thioadenosine phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.28"^^xsd:string) "MeSAdo phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.28"^^xsd:string) "MeSAdo/Ado phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.28"^^xsd:string) "MTAPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:15952893"^^xsd:string) "Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid."^^xsd:string) AnnotationAssertion(rdfs:label "fatty acid amide hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:9224623"^^xsd:string) "Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA."^^xsd:string) AnnotationAssertion( "single-strand selective monofunctional uracil-DNA glycosylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "single-strand selective uracil DNA N-glycosylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "tyrosine-ester sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.9"^^xsd:string) "L-tyrosine methyl ester sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.9"^^xsd:string) "aryl sulfotransferase IV"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.9"^^xsd:string) Annotation( "RHEA:19980"^^xsd:string) "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + L-tyrosine methyl ester = L-tyrosine methyl ester 4-sulfate + adenosine 3',5'-diphosphate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.9"^^xsd:string) "3'-phosphoadenylyl-sulfate:L-tyrosine-methyl-ester sulfotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tyrosine-ester sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a small nuclear RNA (snRNA)."^^xsd:string) AnnotationAssertion( "small nuclear RNA binding"^^xsd:string) AnnotationAssertion(rdfs:label "snRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the U6 small nuclear RNA (U6 snRNA)."^^xsd:string) AnnotationAssertion(rdfs:label "U6 snRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "syntaxin-1 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the SNAP receptor syntaxin-1."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "purine nucleotide binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:15738989"^^xsd:string) Annotation( "PMID:16179945"^^xsd:string) "Catalysis of the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis."^^xsd:string) AnnotationAssertion( "mitochondrial uncoupling protein activity"^^xsd:string) AnnotationAssertion(rdfs:label "oxidative phosphorylation uncoupler activity"^^xsd:string) AnnotationAssertion( "uncoupling protein activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sodium channel regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Modulates the activity of a sodium channel."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "chloride channel regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Modulates the activity of a chloride channel."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "aldosterone receptor"^^xsd:string) AnnotationAssertion(rdfs:label "mineralocorticoid receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:20932876"^^xsd:string) "Combining with a mineralocorticoid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.152"^^xsd:string) "plasma alpha-3-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.152"^^xsd:string) "guanosine diphosphofucose-glucoside alpha1->3-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.152"^^xsd:string) "GDP-beta-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-alpha-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.152"^^xsd:string) "lewis-negative alpha-3-fucosyltransferase activity"^^xsd:string) AnnotationAssertion( "galactoside 3-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.152"^^xsd:string) "GDP-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.152"^^xsd:string) "galactoside 3-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.152"^^xsd:string) "GDP-beta-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.152"^^xsd:string) "Catalysis of the reaction: GDP-beta-L-fucose + beta-D-galactosyl-(1,4)-N-acetyl-D-glucosaminyl-R = GDP + 1,4-beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.152"^^xsd:string) "Lewis-negative alpha-3-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.152"^^xsd:string) "guanosine diphosphofucose-glucoside alpha-1->3-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:PROLINE-MULTI"^^xsd:string) "Catalysis of the reaction: L-glutamate + ATP + NADPH = ADP + L-glutamate gamma-semialdehyde + NADP+ + phosphate."^^xsd:string) AnnotationAssertion( "D1-pyrroline-5-carboxylate synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "delta1-pyrroline-5-carboxylate synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion(rdfs:label "glycolipid transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "AU-specific RNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:7892223"^^xsd:string) Annotation( "PMID:8578590"^^xsd:string) "Interacting selectively and non-covalently with a region of RNA containing frequent adenine and uridine bases."^^xsd:string) AnnotationAssertion( "ARE binding"^^xsd:string) AnnotationAssertion(rdfs:label "AU-rich element binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8578590"^^xsd:string) "Adenylate/uridylate-rich element binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "heparan sulphate 6-O-sulphotransferase activity"^^xsd:string) AnnotationAssertion( "heparin 6-O-sulfotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "heparan sulfate 6-O-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8631808"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 6-O-sulfate; results in 6-O-sulfation of glucosamine residues in heparan sulfate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.4"^^xsd:string) "hydroxyindole O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:2.1.1.4"^^xsd:string) "acetylserotonin N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.4"^^xsd:string) "S-adenosyl-L-methionine:N-acetylserotonin O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.4"^^xsd:string) "N-acetylserotonin O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetylserotonin O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.4"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin. Melatonin is also known as N-acetyl-5-methoxytryptamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.4"^^xsd:string) "acetylserotonin methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.4"^^xsd:string) "hydroxyindole methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "PMID:11938023"^^xsd:string) "Interacting selectively and non-covalently with the sulfonylurea receptor, a regulatory subunit of the ATP-sensitive potassium ion channel."^^xsd:string) AnnotationAssertion( "sulfonylurea receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "sulfonylurea receptor binding"^^xsd:string) AnnotationAssertion( "sulphonylurea receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "very-long-chain-acyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:27283"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a very long chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22."^^xsd:string) AnnotationAssertion( "very long-chain-acyl-CoA dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.10"^^xsd:string) "galactose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UTP:galactose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.10"^^xsd:string) "UTP:alpha-D-hexose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.10"^^xsd:string) "UTP-hexose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.10"^^xsd:string) Annotation( "RHEA:14212"^^xsd:string) "Catalysis of the reaction: alpha-D-galactose 1-phosphate + UTP = diphosphate + UDP-D-galactose."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.10"^^xsd:string) "alpha-D-galactose 1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.10"^^xsd:string) "Gal-1-P uridylyltransferase activity"^^xsd:string) AnnotationAssertion( "UTP:hexose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.10"^^xsd:string) "galactose 1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.10"^^xsd:string) "uridine diphosphate galactose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.10"^^xsd:string) "galactose 1-phosphate uridyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.10"^^xsd:string) "UDPgalactose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.10"^^xsd:string) "uridine diphosphogalactose pyrophosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acyl-CoA delta11-desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.19.5"^^xsd:string) "Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = delta11-acyl-CoA + acceptor + 2 H2O."^^xsd:string) AnnotationAssertion( "acyl-CoA D11-desaturase activity"^^xsd:string) AnnotationAssertion( "acyl-CoA delta(11)-desaturase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_MIT_16mar07"^^xsd:string) "The binding activity of a molecule that brings together an anion exchanger and one or more other molecules, permitting them to function in a coordinated way."^^xsd:string) AnnotationAssertion(rdfs:label "anion exchanger adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5'-flap endonuclease activity"^^xsd:string) AnnotationAssertion( "5' flap endonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9778254"^^xsd:string) "Catalysis of the cleavage of a 5' flap structure in DNA, but not other DNA structures; processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nucleoside-diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "nucleoside-diphosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "type L nucleoside diphosphatase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "IDPase"^^xsd:string) AnnotationAssertion( "apyrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "nucleoside diphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "inosine 5'-diphosphatase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "nucleoside 5'-diphosphatase activity"^^xsd:string) AnnotationAssertion( "nucleoside diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "nucleoside diphosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "inosine diphosphatase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleotide + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "type B nucleoside diphosphatase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "NDPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.15"^^xsd:string) "nucleoside-5-triphosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.15"^^xsd:string) "Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.15"^^xsd:string) "nucleoside triphosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion( "nucleoside triphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.15"^^xsd:string) "nucleoside 5-triphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.15"^^xsd:string) "NTPase activity"^^xsd:string) AnnotationAssertion( "apyrase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nucleoside-triphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.15"^^xsd:string) "unspecific diphosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.15"^^xsd:string) "nucleoside triphosphate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Rab guanyl-nucleotide exchange factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rab family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.2"^^xsd:string) "DHU dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.2"^^xsd:string) "dehydrogenase, dihydrouracil (nicotinamide adenine dinucleotide phosphate)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.2"^^xsd:string) "DHPDH"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.2"^^xsd:string) "4,5-dihydrothymine: oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.2"^^xsd:string) "dihydrothymine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.2"^^xsd:string) "dihydrouracil dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.2"^^xsd:string) "DPD"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.2"^^xsd:string) "hydropyrimidine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.2"^^xsd:string) "5,6-dihydrouracil:NADP+ 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.2"^^xsd:string) "dihydrouracil dehydrogenase (NADP)"^^xsd:string) AnnotationAssertion( "dihydropyrimidine dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dihydropyrimidine dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.2"^^xsd:string) "Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "ssDNA-dependent ATP-dependent DNA helicase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of a DNA helix."^^xsd:string) AnnotationAssertion(rdfs:label "single-stranded DNA-dependent ATP-dependent DNA helicase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10103005"^^xsd:string) "Catalysis of the transfer of the lipoyl group from lipoyl-AMP to the lysine residue of lipoate-dependent enzyme."^^xsd:string) AnnotationAssertion(rdfs:label "lipoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Ral GTPase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Increases the rate of GTP hydrolysis by a GTPase of the Ral family."^^xsd:string) AnnotationAssertion(Annotation( "GOC:pg"^^xsd:string) "Ral GAP activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "SH3 domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "Pfam:PF00018"^^xsd:string) "Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "deoxycytidyl transferase activity"^^xsd:string) AnnotationAssertion( "deoxycytidyl transferase activity, template-dependent"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10535901"^^xsd:string) "Catalysis of the insertion of a dCMP residue opposite a template abasic site in DNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of cholesterol into, out of or within a cell, or between cells. Cholesterol is the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones."^^xsd:string) AnnotationAssertion(rdfs:label "cholesterol transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phospholipid scramblase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:cjm"^^xsd:string) Annotation( "PMID:20043909"^^xsd:string) Annotation( "PMID:20302864"^^xsd:string) "Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, by an ATP-independent mechanism."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with any triester of glycerol."^^xsd:string) AnnotationAssertion(rdfs:label "triglyceride binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "triacylglycerol binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "poly(C) binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a sequence of cytosine residues in an RNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "poly(C) RNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "poly(rC) binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "uridine-rich cytoplasmic polyadenylation element binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "PMID:7954828"^^xsd:string) "Interacting selectively and non-covalently with U-rich sequence in the 3'-end of nuclear-transcribed mRNAs; required for cytoplasmic polyadenylylation."^^xsd:string) AnnotationAssertion(rdfs:label "uridine-rich cytoplasmic polyadenylylation element binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:7954828"^^xsd:string) "U-rich CPE binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclic nucleotide-dependent guanyl-nucleotide exchange factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9856955"^^xsd:string) "Stimulates the exchange of guanyl nucleotides associated with a GTPase; dependent on the presence of a cyclic nucleotide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "FGF 3 binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9806903"^^xsd:string) "Interacting selectively and non-covalently with a fibroblast growth factor."^^xsd:string) AnnotationAssertion( "fibroblast growth factor 1 binding"^^xsd:string) AnnotationAssertion( "fibroblast growth factor 6 binding"^^xsd:string) AnnotationAssertion( "FGF 5 binding"^^xsd:string) AnnotationAssertion( "fibroblast growth factor 3 binding"^^xsd:string) AnnotationAssertion(rdfs:label "fibroblast growth factor binding"^^xsd:string) AnnotationAssertion( "FGF 1 binding"^^xsd:string) AnnotationAssertion( "FGF binding"^^xsd:string) AnnotationAssertion( "fibroblast growth factor 5 binding"^^xsd:string) AnnotationAssertion( "fibroblast growth factor 2 binding"^^xsd:string) AnnotationAssertion( "FGF 4 binding"^^xsd:string) AnnotationAssertion( "FGF 2 binding"^^xsd:string) AnnotationAssertion( "fibroblast growth factor 4 binding"^^xsd:string) AnnotationAssertion( "FGF 6 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "SIR2"^^xsd:string) AnnotationAssertion(rdfs:label "NAD-dependent histone deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.17"^^xsd:string) Annotation( "EC:3.5.1.98"^^xsd:string) Annotation( "RHEA:24551"^^xsd:string) "Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Rab interactor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases."^^xsd:string) AnnotationAssertion(rdfs:label "Rab GTPase binding"^^xsd:string) AnnotationAssertion( "Rab escort protein activity"^^xsd:string) AnnotationAssertion( "REP"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Wnt-protein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with Wnt-protein, a secreted growth factor involved in signaling."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tRNA dihydrouridine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11983710"^^xsd:string) "Catalysis of the reaction: tRNA-uracil + acceptor = tRNA-dihydrouridine + reduced acceptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the enzyme DEAD/H-box RNA helicase."^^xsd:string) AnnotationAssertion(rdfs:label "DEAD/H-box RNA helicase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sodium:dicarboxylate symporter activity"^^xsd:string) AnnotationAssertion( "sodium:dicarboxylate cotransporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "semaphorin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:15239958"^^xsd:string) "Combining with a semaphorin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.92"^^xsd:string) "vanin"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.92"^^xsd:string) "(R)-pantetheine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.92"^^xsd:string) "pantetheinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.92"^^xsd:string) Annotation( "RHEA:13448"^^xsd:string) "Catalysis of the reaction: (R)-pantetheine + H(2)O = (R)-pantothenate + cysteamine."^^xsd:string) AnnotationAssertion(rdfs:label "pantetheine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.92"^^xsd:string) "vanin-1"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Ral interactor activity"^^xsd:string) AnnotationAssertion(rdfs:label "Ral GTPase binding"^^xsd:string) AnnotationAssertion( "GTP-Ral binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with Ral protein, any member of the Ral subfamily of the Ras superfamily of monomeric GTPases."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 1,3-bisphosphate + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "inositol-1,3,4-trisphosphate 4-phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aryl hydrocarbon receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with an aryl hydrocarbon receptor."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0721662544"^^xsd:string) "Interacting selectively and non-covalently with vinculin, a protein found in muscle, fibroblasts, and epithelial cells that binds actin and appears to mediate attachment of actin filaments to integral proteins of the plasma membrane."^^xsd:string) AnnotationAssertion(rdfs:label "vinculin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.2.9"^^xsd:string) "oxoprolinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.9"^^xsd:string) "5-oxoprolinase (ATP-hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.9"^^xsd:string) "5-oxo-L-proline amidohydrolase (ATP-hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.9"^^xsd:string) "5-oxoprolinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.9"^^xsd:string) "pyroglutamic hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.9"^^xsd:string) "5-oxo-L-prolinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.9"^^xsd:string) "pyroglutamase (ATP-hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.9"^^xsd:string) "pyroglutamate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.9"^^xsd:string) "L-pyroglutamate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.9"^^xsd:string) "5-OPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.9"^^xsd:string) "pyroglutamase (ATP-hydrolyzing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.9"^^xsd:string) "pyroglutamase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.9"^^xsd:string) Annotation( "RHEA:10351"^^xsd:string) "Catalysis of the reaction: 5-oxo-L-proline + ATP + 2 H(2)O = L-glutamate + ADP + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "5-oxoprolinase (ATP-hydrolyzing) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CDP-alcohol phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "Wikipedia:Serine_hydrolase"^^xsd:string) "Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)."^^xsd:string) AnnotationAssertion(rdfs:label "serine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.20"^^xsd:string) Annotation( "RHEA:20444"^^xsd:string) "Catalysis of the reaction: L-cysteine + O(2) = 3-sulfino-L-alanine + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "cysteine dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.20"^^xsd:string) "glycine methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.20"^^xsd:string) "GNMT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.20"^^xsd:string) "S-adenosyl-L-methionine:glycine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.20"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.20"^^xsd:string) "S-adenosyl-L-methionine:glycine N-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidylinositol N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.198"^^xsd:string) "uridine diphosphoacetylglucosamine alpha-1,6-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.198"^^xsd:string) "uridine diphosphoacetylglucosamine alpha1,6-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.198"^^xsd:string) "UDP-N-acetyl-D-glucosamine:phosphatidylinositol N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.198"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + phosphatidylinositol = UDP + N-acetyl-D-glucosaminylphosphatidylinositol."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.198"^^xsd:string) "UDP-N-acetyl-D-glucosamine:1-phosphatidyl-1D-myo-inositol 6-(N-acetyl-alpha-D-glucosaminyl)transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.1.14"^^xsd:string) "diphthamide synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "diphthine-ammonia ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.14"^^xsd:string) "diphthamide synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.14"^^xsd:string) Annotation( "RHEA:19756"^^xsd:string) "Catalysis of the reaction: ATP + diphthine + NH(4)(+) = ADP + diphthamide + H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.14"^^xsd:string) "diphthine:ammonia ligase (ADP-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.17"^^xsd:string) "aspartate acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aspartate N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.17"^^xsd:string) "L-aspartate N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.17"^^xsd:string) "acetyl-CoA:L-aspartate N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.17"^^xsd:string) Annotation( "RHEA:14168"^^xsd:string) "Catalysis of the reaction: L-aspartate + acetyl-CoA = N-acetyl-L-aspartate + CoA + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.96"^^xsd:string) "mucus glycoprotein fatty acyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.96"^^xsd:string) "palmitoyl-CoA:glycoprotein N-palmitoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.96"^^xsd:string) "Catalysis of the reaction: palmitoyl-CoA + glycoprotein = CoA + N-palmitoylglycoprotein."^^xsd:string) AnnotationAssertion(rdfs:label "glycoprotein N-palmitoyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone-lysine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.43"^^xsd:string) "protein methyltransferase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.43"^^xsd:string) Annotation( "RESID:AA0074"^^xsd:string) Annotation( "RESID:AA0075"^^xsd:string) Annotation( "RESID:AA0076"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.43"^^xsd:string) "histone H1-specific S-adenosylmethionine:protein-lysine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.43"^^xsd:string) "protein methylase III activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histone-lysine N-methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.43"^^xsd:string) "S-adenosyl-L-methionine:histone-L-lysine 6-N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.43"^^xsd:string) "S-adenosyl-L-methionine:histone-L-lysine N6-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.43"^^xsd:string) "protein methylase 3 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.43"^^xsd:string) "protein (lysine) methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.60"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + calmodulin L-lysine = S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.60"^^xsd:string) "S-adenosyl-L-methionine:calmodulin-L-lysine N6-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.60"^^xsd:string) "S-adenosylmethionine:calmodulin (lysine) N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.60"^^xsd:string) "S-adenosyl-L-methionine:calmodulin-L-lysine 6-N-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "calmodulin-lysine N-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peptidyl-lysine N6-myristoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a myristoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a palmitoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule."^^xsd:string) AnnotationAssertion(rdfs:label "peptidyl-lysine N6-palmitoyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.85"^^xsd:string) "protein (histidine) methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.85"^^xsd:string) "protein methylase IV activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.85"^^xsd:string) "S-adenosyl methionine:protein-histidine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.85"^^xsd:string) "S-adenosyl-L-methionine:protein-L-histidine N-tele-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.85"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + protein L-histidine = S-adenosyl-L-homocysteine + protein N-methyl-L-histidine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.85"^^xsd:string) "actin-specific histidine methyltransferase activity"^^xsd:string) AnnotationAssertion( "peptidyl-histidine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-histidine N-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NAD(P)-cysteine ADP-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.-"^^xsd:string) "Catalysis of the reaction: NAD(P)+ + L-cysteine = nicotinamide + N2-(ADP-D-ribosyl)-L-cysteine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone arginine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: histone L-arginine + ATP = histone N(omega)-phospho-L-arginine + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion( "histone-arginine kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.1.2"^^xsd:string) Annotation( "RHEA:12495"^^xsd:string) "Catalysis of the reaction: L-methionine = D-methionine."^^xsd:string) AnnotationAssertion(rdfs:label "methionine racemase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "proline racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.4"^^xsd:string) Annotation( "RHEA:10683"^^xsd:string) "Catalysis of the reaction: L-proline = D-proline."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.1.5"^^xsd:string) "Catalysis of the reaction: L-lysine = D-lysine."^^xsd:string) AnnotationAssertion(rdfs:label "lysine racemase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.1.6"^^xsd:string) Annotation( "RHEA:13916"^^xsd:string) "Catalysis of the reaction: L-threonine = D-threonine."^^xsd:string) AnnotationAssertion(rdfs:label "threonine racemase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NAD(P)-asparagine ADP-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.-"^^xsd:string) "Catalysis of the reaction: NAD(P)+ + L-asparagine = nicotinamide + N2-(ADP-D-ribosyl)-L-asparagine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NAD(P)-serine ADP-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.-"^^xsd:string) "Catalysis of the reaction: NAD(P)+ + L-serine = nicotinamide + N2-(ADP-D-ribosyl)-L-serine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19058272"^^xsd:string) "Catalysis of the reduction of a peptide-linked oxazoline to oxazole."^^xsd:string) AnnotationAssertion(rdfs:label "peptidyl-oxazoline dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peptidyl-thiazoline dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19058272"^^xsd:string) "Catalysis of the reduction of a peptide-linked thiazoline to thiazole."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:2570347"^^xsd:string) "Catalysis of the posttranslational transfer of one or more glutamic acid residues to the C-terminus of ribosomal protein S6."^^xsd:string) AnnotationAssertion(rdfs:label "ribosomal S6-glutamic acid ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:16244137"^^xsd:string) "Increases the activity of urease by promoting the incorporation of nickel into the active site."^^xsd:string) AnnotationAssertion( "urease activase activity"^^xsd:string) AnnotationAssertion(rdfs:label "urease activator activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + biotin + protein = AMP + diphosphate + biotin-protein."^^xsd:string) AnnotationAssertion(rdfs:label "biotin-protein ligase activity"^^xsd:string) AnnotationAssertion( "biotin-apoprotein ligase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein-serine epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.16"^^xsd:string) "protein-serine racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.16"^^xsd:string) "Catalysis of the reaction: (protein)-L-serine = (protein)-D-serine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.214"^^xsd:string) "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,3-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.214"^^xsd:string) "GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-1,3-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycoprotein 3-alpha-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion( "GDP-L-fucose:asparagine-linked N-acetylglucosamine alpha(1,3)-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.214"^^xsd:string) "GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fuc-alpha-1->6-GlcNAc)-Asn-peptide) alpha-1->3-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.214"^^xsd:string) "GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fucalpha1->6-GlcNAc)-Asn-peptide) alpha1->3-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.214"^^xsd:string) "GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 3-alpha-L-fucosyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.214"^^xsd:string) "GDP-L-Fuc:Asn-linked GlcNAc alpha-1,3-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.214"^^xsd:string) "GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of 4-N-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 3-alpha-L-fucosyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.214"^^xsd:string) Annotation( "RHEA:24447"^^xsd:string) "Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.214"^^xsd:string) "GDP-L-Fuc:Asn-linked GlcNAc alpha1,3-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.214"^^xsd:string) "GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fucalpha1->6GlcNAc)-Asn-peptide) alpha1->3-fucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-N-acetylglucosamine:serine-protein N-acetylglucosamine-1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9353330"^^xsd:string) "Catalysis of the transfer of N-acetylglucosamine-1-phosphate to a serine residue in a protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GDP-mannose:serine-protein mannose-1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:10037765"^^xsd:string) "Catalysis of the transfer of mannose-1-phosphate to a serine residue in a protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "protein phosphatase methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein C-terminal leucine carboxyl O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8514774"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein."^^xsd:string) AnnotationAssertion( "protein-leucine O-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:3301403"^^xsd:string) "The action characteristic of prothoracicotrophic hormone, a peptide hormone that is secreted by the brain and, upon receptor binding, acts on the prothoracic gland to stimulate the release of ecdysone in insects."^^xsd:string) AnnotationAssertion(rdfs:label "prothoracicotrophic hormone activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pinocarveol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0717"^^xsd:string) "Catalysis of the reaction: pinocarveol = pinocarvone + 2 H+ + 2 e-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chloral hydrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0229"^^xsd:string) "Catalysis of the reactions: chloral hydrate = 3 H+ + 2 e- + trichloroacetate, and chloral hydrate + H2 = H2O + trichloroethanol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0638"^^xsd:string) "Catalysis of the reaction: hydroxymethylmethylsilanediol + O2 + 2 H+ + 2 e- = formylmethylsilanediol + 2 H2O."^^xsd:string) AnnotationAssertion(rdfs:label "hydroxymethylmethylsilanediol oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0032"^^xsd:string) "Catalysis of the reaction: (S)-1-phenylethanol = acetophenone + H2."^^xsd:string) AnnotationAssertion(rdfs:label "1-phenylethanol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0710"^^xsd:string) "Catalysis of the reaction: myrtenol + O2 + 2 H+ + 2 e- = 2 H2O + myrtenal."^^xsd:string) AnnotationAssertion(rdfs:label "myrtenol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "epoxide dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0595"^^xsd:string) "Catalysis of the reaction: ethene oxide + NAD+ + CoA-SH = NADH + H+ + acetyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0427"^^xsd:string) "Catalysis of the reaction: 5-exo-hydroxycamphor + NAD+ = NADH + H+ + 2,5-diketocamphane."^^xsd:string) AnnotationAssertion(rdfs:label "5-exo-hydroxycamphor dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxytetrahydrofuran dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0018"^^xsd:string) "Catalysis of the reaction: 2-hydroxytetrahydrofuran = 2 H+ + 2 e- + butyrolactone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.36"^^xsd:string) "D(-)-beta-hydroxybutyryl CoA-NADP oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.36"^^xsd:string) "acetoacetyl coenzyme A reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.36"^^xsd:string) "(R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.36"^^xsd:string) "short chain beta-ketoacetyl(acetoacetyl)-CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.36"^^xsd:string) "beta-ketoacyl-CoA reductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.36"^^xsd:string) "D-3-hydroxyacyl-CoA reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetoacetyl-CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.36"^^xsd:string) "hydroxyacyl coenzyme-A dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.36"^^xsd:string) "NADPH:acetoacetyl-CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.36"^^xsd:string) "NADP-linked acetoacetyl CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.36"^^xsd:string) "(R)-3-hydroxyacyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.36"^^xsd:string) "Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alcohol dehydrogenase [NAD(P)+] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.71"^^xsd:string) "Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.71"^^xsd:string) "alcohol:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.71"^^xsd:string) "aldehyde reductase (NADPH/NADH)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aryl-alcohol dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.90"^^xsd:string) "p-hydroxybenzyl alcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion( "benzyl alcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.90"^^xsd:string) "Catalysis of the reaction: an aromatic alcohol + NAD+ = an aromatic aldehyde + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.90"^^xsd:string) "aryl-alcohol:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.144"^^xsd:string) "perillyl-alcohol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.144"^^xsd:string) Annotation( "RHEA:10667"^^xsd:string) "Catalysis of the reaction: NAD(+) + perillyl alcohol = H(+) + NADH + perillyl aldehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.144"^^xsd:string) "perillyl alcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "perillyl-alcohol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.223"^^xsd:string) "(-)-trans-isopiperitenol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "isopiperitenol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.223"^^xsd:string) Annotation( "RHEA:20863"^^xsd:string) "Catalysis of the reaction: (1S,6R)-isopiperitenol + NAD(+) = (6R)-isoperitenone + H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.243"^^xsd:string) "(-)-trans-carveol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.243"^^xsd:string) Annotation( "RHEA:13632"^^xsd:string) "Catalysis of the reaction: (1S,5R)-carveol + NADP(+) = (R)-carvone + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.243"^^xsd:string) "(-)-trans-carveol dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "carveol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclohexanol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.245"^^xsd:string) "cyclohexanol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.245"^^xsd:string) "Catalysis of the reaction: cyclohexanol + NAD+ = cyclohexanone + NADH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.256"^^xsd:string) "Catalysis of the reaction: fluoren-9-ol + 2 NADP+ = fluoren-9-one + 2 NADPH + 2 H+."^^xsd:string) AnnotationAssertion( "9-fluorenol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.256"^^xsd:string) "fluoren-9-ol:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "fluoren-9-ol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.257"^^xsd:string) Annotation( "RHEA:24415"^^xsd:string) "Catalysis of the reaction: 4-(hydroxymethyl)benzenesulfonate + NAD(+) = 4-formylbenzenesulfonate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.257"^^xsd:string) "4-(hydroxymethyl)benzenesulfonate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-(hydroxymethyl)benzenesulfonate dehydrogenase activity"^^xsd:string) AnnotationAssertion( "4-sulfobenzyl alcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion( "4-(hydroxymethyl)benzenesulphonate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "6-hydroxyhexanoate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.258"^^xsd:string) Annotation( "RHEA:14228"^^xsd:string) "Catalysis of the reaction: 6-hydroxyhexanoate + NAD(+) = 6-oxohexanoate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.258"^^xsd:string) "6-hydroxyhexanoate:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.259"^^xsd:string) "3-hydroxypimeloyl-CoA:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxypimeloyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.259"^^xsd:string) Annotation( "RHEA:11171"^^xsd:string) "Catalysis of the reaction: 3-hydroxypimelyl-CoA + NAD(+) = 3-oxopimelyl-CoA + H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.38"^^xsd:string) "4-hydroxy-2-methoxybenzyl alcohol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.38"^^xsd:string) Annotation( "RHEA:10039"^^xsd:string) "Catalysis of the reaction: O(2) + vanillyl alcohol = H(2)O(2) + vanillin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.38"^^xsd:string) "vanillyl alcohol:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "vanillyl-alcohol oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0735"^^xsd:string) "Catalysis of the reaction: (1S,2S,4R)-limonene-1,2-diol + DCPIP+ = DCPIPH + H+ + (1S,4R)-1-hydroxy-2-oxolimonene."^^xsd:string) AnnotationAssertion(rdfs:label "limonene-1,2-diol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glutathione-independent formaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.46"^^xsd:string) Annotation( "RHEA:16428"^^xsd:string) "Catalysis of the reaction: formaldehyde + H(2)O + NAD(+) = formate + 2 H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.46"^^xsd:string) "formaldehyde:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "formaldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alcohol dehydrogenase (acceptor) activity"^^xsd:string) AnnotationAssertion( "PQQ-dependent alcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.8"^^xsd:string) "MDH"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.8"^^xsd:string) "alcohol:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.8"^^xsd:string) "quinohemoprotein alcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.8"^^xsd:string) "primary alcohol dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.8"^^xsd:string) "alcohol:(acceptor) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.8"^^xsd:string) "quinoprotein alcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.8"^^xsd:string) "quinoprotein ethanol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.8"^^xsd:string) "Catalysis of the reaction: a primary alcohol + acceptor = an aldehyde + reduced acceptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "myrtenal dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0711"^^xsd:string) "Catalysis of the reaction: myrtenal + H2O = 2 H+ + 2 e- + myrtenic acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-hydroxybutaraldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0014"^^xsd:string) "Catalysis of the reaction: 4-hydroxybutyraldehyde + H2O = 2 H+ + 2 e- + 4-hydroxybutanoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0447"^^xsd:string) "Catalysis of the reaction: 4-chlorobenzaldehyde + 2 H2O = 4-chlorobenzoate + 2 H+ + 2 e-."^^xsd:string) AnnotationAssertion(rdfs:label "4-chlorobenzaldehyde oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0485"^^xsd:string) "Catalysis of the reaction: 1-hydroxy-2-naphthaldehyde + NAD+ + H2O = NADH + H+ + 1-hydroxy-2-naphthoate."^^xsd:string) AnnotationAssertion(rdfs:label "1-hydroxy-2-naphthaldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0744"^^xsd:string) "Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + cis-2-methyl-5-isopropylhexa-2,5-dienoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "cis-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0490"^^xsd:string) "Catalysis of the reaction: 2-carboxybenzaldehyde + NAD+ + H2O = NADH + 2 H+ + phthalate."^^xsd:string) AnnotationAssertion(rdfs:label "2-carboxybenzaldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0745"^^xsd:string) "Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + trans-2-methyl-5-isopropylhexa-2,5-dienoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "trans-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "benzaldehyde dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.7"^^xsd:string) "Catalysis of the reaction: benzaldehyde + NADP+ + H2O = benzoate + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.7"^^xsd:string) "benzaldehyde:NADP+ oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.7"^^xsd:string) "NADP-linked benzaldehyde dehydrogenase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "malonate-semialdehyde dehydrogenase (acetylating) activity"^^xsd:string) AnnotationAssertion( "malonic semialdehyde oxidative decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.18"^^xsd:string) "Catalysis of the reaction: 3-oxopropanoate + CoA + NADP+ = acetyl-CoA + CO2 + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.18"^^xsd:string) "3-oxopropanoate:NAD(P)+ oxidoreductase (decarboxylating, CoA-acetylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "benzaldehyde dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.28"^^xsd:string) "benzaldehyde (NAD) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.28"^^xsd:string) "Catalysis of the reaction: benzaldehyde + NAD+ + H2O = benzoate + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.28"^^xsd:string) "benzaldehyde:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.60"^^xsd:string) "carboxymethylhydroxymuconic semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.60"^^xsd:string) "Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.60"^^xsd:string) "5-carboxymethyl-2-hydroxymuconic-semialdehyde:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-hydroxymuconic-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.61"^^xsd:string) "4-hydroxymuconic-semialdehyde:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.61"^^xsd:string) Annotation( "RHEA:22423"^^xsd:string) "Catalysis of the reaction: cis,trans-4-hydroxymuconate semialdehyde + H(2)O + NAD(+) = 2 H(+) + maleylacetate + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-formylbenzenesulfonate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.62"^^xsd:string) "4-formylbenzenesulfonate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.62"^^xsd:string) Annotation( "RHEA:18836"^^xsd:string) "Catalysis of the reaction: 4-formylbenzenesulfonate + H(2)O + NAD(+) = 4-sulfobenzoate + 2 H(+) + NADH."^^xsd:string) AnnotationAssertion( "4-formylbenzenesulphonate dehydrogenase activity"^^xsd:string) AnnotationAssertion( "toluene-sulfonate aldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "6-oxohexanoate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.63"^^xsd:string) "Catalysis of the reaction: 6-oxohexanoate + NADP+ + H2O = adipate + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.63"^^xsd:string) "6-oxohexanoate:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.64"^^xsd:string) "Catalysis of the reaction: 4-hydroxybenzaldehyde + NAD+ + H2O = 4-hydroxybenzoate + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.64"^^xsd:string) "p-hydroxybenzaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.64"^^xsd:string) "3-hydroxybenzaldehyde:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxybenzaldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.65"^^xsd:string) "Catalysis of the reaction: salicylaldehyde + NAD+ + H2O = salicylate + NADH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "salicylaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.65"^^xsd:string) "salicylaldehyde:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0169"^^xsd:string) "Catalysis of the reaction: methyl ethyl ketone + O2 = H2O + ethyl acetate."^^xsd:string) AnnotationAssertion(rdfs:label "2-butanone oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "vanillate O-demethylase (anaerobic) activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0758"^^xsd:string) "Catalysis of the reaction: vanillate + Co+ = Co3+-CH3 + 3,4-dihydroxybenzoate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aryl-aldehyde oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.9"^^xsd:string) "aryl-aldehyde:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.9"^^xsd:string) "Catalysis of the reaction: an aromatic aldehyde + O2 + H2O = an aromatic acid + hydrogen peroxide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.82"^^xsd:string) Annotation( "RHEA:13024"^^xsd:string) "Catalysis of the reaction: H(+) + NADH + O(2) + vanillate = 3,4-dihydroxybenzoate + formaldehyde + H(2)O + NAD(+)."^^xsd:string) AnnotationAssertion( "vanillate demethylase (aerobic) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.82"^^xsd:string) "vanillate:oxygen oxidoreductase (demethylating)"^^xsd:string) AnnotationAssertion( "vanillate demethylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "vanillate monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.82"^^xsd:string) "4-hydroxy-3-methoxybenzoate demethylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.3.13"^^xsd:string) "4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxyphenylpyruvate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.13"^^xsd:string) Annotation( "RHEA:17200"^^xsd:string) "Catalysis of the reaction: 2 (4-hydroxyphenyl)pyruvate + O(2) = 2 (4-hydroxyphenyl)acetate + 2 CO(2)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.7.2"^^xsd:string) "2-ketobutyrate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-oxobutyrate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.2"^^xsd:string) "alpha-ketobutyrate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.2"^^xsd:string) "alpha-ketobutyrate-ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.2"^^xsd:string) "2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propionylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.2"^^xsd:string) "Catalysis of the reaction: 2-oxobutanoate + CoA + oxidized ferredoxin = propanoyl-CoA + CO2 + reduced ferredoxin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.2"^^xsd:string) "2-oxobutyrate-ferredoxin oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.99.2"^^xsd:string) "carbon-monoxide:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "carbon-monoxide dehydrogenase (acceptor) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.99.2"^^xsd:string) "Catalysis of the reaction: CO + H2O + acceptor = CO2 + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.99.2"^^xsd:string) "anaerobic carbon monoxide dehydrogenase activity"^^xsd:string) AnnotationAssertion( "carbon monoxide dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.99.5"^^xsd:string) Annotation( "RHEA:19844"^^xsd:string) "Catalysis of the reaction: N-formylmethanofuran + A + H(2)O + H(+) = AH(2) + CO(2) + methanofuran."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.99.5"^^xsd:string) "formylmethanofuran:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "formylmethanofuran dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.99.5"^^xsd:string) "formylmethanofuran:(acceptor) oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carvone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0732"^^xsd:string) "Catalysis of the reaction: carvone + 2 H+ + 2 e- = dihydrocarvone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0192"^^xsd:string) "Catalysis of the reaction: 2-hydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 2-ketocyclohexane-1-carboxyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0205"^^xsd:string) "Catalysis of the reaction: 2,6-dihydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "2,6-dihydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "DDMS dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0514"^^xsd:string) "Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethene + 2 H+ + 2 e- = 1-chloro-2,2-bis(4-chlorophenyl)ethane. 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU; 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS."^^xsd:string) AnnotationAssertion(rdfs:label "1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0308"^^xsd:string) "Catalysis of the reaction: cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol + NAD+ = NADH + H+ + 3-(2,3-dihydroxyphenyl)propionate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0451"^^xsd:string) "Catalysis of the reaction: cis-2,3-dihydrodiol DDT + NADP+ = NADPH + 2,3-dihydroxy DDT."^^xsd:string) AnnotationAssertion(rdfs:label "cis-2,3-dihydrodiol DDT dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0575"^^xsd:string) "Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + NAD+ = NADH + H+ + 9,10-dihydroxyphenanthrene."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cis-chlorobenzene dihydrodiol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0411"^^xsd:string) "Catalysis of the conversion of a di- or tetrachlorinated dienol to the corresponding catechol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0553"^^xsd:string) "Catalysis of the reaction: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol + NAD+ = NADH + H+ + 2,5-dichlorohydroquinone."^^xsd:string) AnnotationAssertion(rdfs:label "2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0574"^^xsd:string) "Catalysis of the reaction: trans-1,2-dihydrodiolphenanthrene + NAD+ = H+ + NADH + 1,2-dihydroxyphenanthrene."^^xsd:string) AnnotationAssertion(rdfs:label "trans-1,2-dihydrodiolphenanthrene dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.19"^^xsd:string) "cis-benzene glycol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.19"^^xsd:string) "cis-1,2-dihydrobenzene-1,2-diol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cis-1,2-dihydrobenzene-1,2-diol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.19"^^xsd:string) "Catalysis of the reaction: cis-1,2-dihydrobenzene-1,2-diol + NAD+ = catechol + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.19"^^xsd:string) "cis-1,2-dihydrocyclohexa-3,5-diene (nicotinamide adenine dinucleotide) oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.29"^^xsd:string) "cis-naphthalene dihydrodiol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.29"^^xsd:string) "Catalysis of the reaction: cis-1,2-dihydronaphthalene-1,2-diol + NAD+ = naphthalene-1,2-diol + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.29"^^xsd:string) "cis-dihydrodiol naphthalene dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.29"^^xsd:string) "(+)-cis-naphthalene dihydrodiol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.29"^^xsd:string) "naphthalene dihydrodiol dehydrogenase activity"^^xsd:string) AnnotationAssertion( "1,2-dihydroxy-1,2-dihydroxynaphthalene dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.29"^^xsd:string) "cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "maleylacetate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.32"^^xsd:string) "maleolylacetate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.32"^^xsd:string) "Catalysis of the reaction: 3-oxoadipate + NAD(P)+ = 2-maleylacetate + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.32"^^xsd:string) "3-oxoadipate:NAD(P)+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.49"^^xsd:string) "(+)-cis-3,4-dihydrophenanthrene-3,4-diol:NAD+ 3,4-oxidoreductase activity"^^xsd:string) AnnotationAssertion( "cis-3,4-dihydroxy-3,4-dihydrophenanthrene dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.49"^^xsd:string) Annotation( "RHEA:16256"^^xsd:string) "Catalysis of the reaction: (3S,4R)-3,4-dihydrophenanthrene-3,4-diol + NAD(+) = H(+) + NADH + phenanthrene-3,4-diol."^^xsd:string) AnnotationAssertion(rdfs:label "cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:BENZOATE-CIS-DIOL-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate + NAD+ = catechol + CO2 + NADH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase activity"^^xsd:string) AnnotationAssertion( "benzoate cis-diol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.56"^^xsd:string) "biphenyl-2,3-dihydro-2,3-diol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.56"^^xsd:string) "Catalysis of the reaction: cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.56"^^xsd:string) "cis-3-phenylcyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity"^^xsd:string) AnnotationAssertion( "2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.57"^^xsd:string) Annotation( "RHEA:10083"^^xsd:string) "Catalysis of the reaction: dihydrophloroglucinol + NADP(+) = H(+) + NADPH + phloroglucinol."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.57"^^xsd:string) "dihydrophloroglucinol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phloroglucinol reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.58"^^xsd:string) "cis-2,3-dihydroxy-2,3-dihydro-p-cumate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.58"^^xsd:string) Annotation( "RHEA:23775"^^xsd:string) "Catalysis of the reaction: cis-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+) = 2,3-dihydroxy-p-cumate + H(+) + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.60"^^xsd:string) Annotation( "RHEA:24191"^^xsd:string) "Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD(+) = 1,2-dihydroxydibenzothiophene + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.60"^^xsd:string) "cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dibenzothiophene dihydrodiol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pimeloyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.62"^^xsd:string) "pimeloyl-CoA:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.62"^^xsd:string) Annotation( "RHEA:19668"^^xsd:string) "Catalysis of the reaction: NAD(+) + pimelyl-CoA = 2,3-didehydropimeloyl-CoA + H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,4-dichlorobenzoyl-CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.63"^^xsd:string) "4-chlorobenzoyl-CoA:NADP+ oxidoreductase (halogenating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.63"^^xsd:string) Annotation( "RHEA:23079"^^xsd:string) "Catalysis of the reaction: 4-chlorobenzoyl-CoA + chloride + NADP(+) = 2,4-dichlorobenzoyl-CoA + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.64"^^xsd:string) Annotation( "RHEA:13840"^^xsd:string) "Catalysis of the reaction: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) = 4,5-dihydroxyphthalate + H(+) + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "phthalate 4,5-cis-dihydrodiol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.64"^^xsd:string) "cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.65"^^xsd:string) "5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.65"^^xsd:string) Annotation( "RHEA:24559"^^xsd:string) "Catalysis of the reaction: 5,6-dihydroxy-3-methyl-5,6-dihydroquinolin-2(1H)-one + NAD(+) = 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + H(+) + NADH."^^xsd:string) AnnotationAssertion( "5,6-dihydrodiol-3-methyl-2-oxo-1,2-dihydroquinoline dehydrogenase"^^xsd:string) AnnotationAssertion(rdfs:label "5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cis-dihydroethylcatechol dehydrogenase activity"^^xsd:string) AnnotationAssertion( "cis-ethylbenzene glycol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.66"^^xsd:string) "cis-1,2-dihydro-3-ethylcatechol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.66"^^xsd:string) Annotation( "RHEA:18104"^^xsd:string) "Catalysis of the reaction: cis-1,2-dihydro-3-ethylcatechol + NAD(+) = 3-ethylcatechol + H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.67"^^xsd:string) "Catalysis of the reaction: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ = 4-methylcatechol + NADPH + H+ + CO2."^^xsd:string) AnnotationAssertion( "4-methylcyclohexa-3,5-diene-1,2-cis-diol-1-carboxylic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.67"^^xsd:string) "cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate:NAD(P)+ oxidoreductase (decarboxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.68"^^xsd:string) "1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate:NAD+ oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.68"^^xsd:string) Annotation( "RHEA:15660"^^xsd:string) "Catalysis of the reaction: 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylate + NAD(+) = 3-methylcatechol + CO(2) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "KEGG:R02451"^^xsd:string) "cyclohexa-1,5-diene-1-carbonyl-CoA:ferredoxin oxidoreductase (aromatizing, ATP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.8"^^xsd:string) "benzoyl-CoA reductase (dearomatizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.8"^^xsd:string) "Catalysis of the reaction: 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 phosphate = 2 ATP + 2 H(2)O + benzoyl-CoA + reduced ferredoxin."^^xsd:string) AnnotationAssertion(rdfs:label "benzoyl-CoA reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.99.17"^^xsd:string) "quinoline:acceptor 2-oxidoreductase (hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.17"^^xsd:string) "Catalysis of the reaction: quinoline + acceptor + H2O = isoquinolin-1(2H)-one + reduced acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "quinoline 2-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acetophenone carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0033"^^xsd:string) "Catalysis of the reaction: acetophenone + CO2 = H+ + benzoyl acetate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "KEGG:R05316"^^xsd:string) "Catalysis of the reaction: benzoyl-CoA + oxidized ferredoxin + H2O = 4-hydroxybenzoyl-CoA + reduced ferredoxin."^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxybenzoyl-CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.9"^^xsd:string) "4-hydroxybenzoyl-coA reductase (dehydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.9"^^xsd:string) "4-hydroxybenzoyl-coA:(acceptor) oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0342"^^xsd:string) "Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 H+ + 2 e- = NH3 + benzoyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "2-aminobenzoyl-CoA reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclohexylamine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.12"^^xsd:string) "Catalysis of the reaction: cyclohexylamine + O2 + H2O = cyclohexanone + NH3 + hydrogen peroxide."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.12"^^xsd:string) "cyclohexylamine:oxygen oxidoreductase (deaminating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0589"^^xsd:string) "Catalysis of the reaction: iminodiacetate + OH- = H+ + 2 e- + glyoxylate + glycine."^^xsd:string) AnnotationAssertion(rdfs:label "iminodiacetate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nitrilotriacetate monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0587"^^xsd:string) "Catalysis of the reaction: nitrilotriacetate + NADH + H+ + O2 = NAD+ + H2O + glyoxylate + iminodiacetate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.3.6"^^xsd:string) Annotation( "RHEA:10015"^^xsd:string) "Catalysis of the reaction: (R)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.6"^^xsd:string) "D-6-hydroxynicotine oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(R)-6-hydroxynicotine oxidase activity"^^xsd:string) AnnotationAssertion( "6-hydroxy-D-nicotine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.6"^^xsd:string) "(R)-6-hydroxynicotine:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-6-hydroxynicotine oxidase activity"^^xsd:string) AnnotationAssertion( "6-hydroxy-L-nicotine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.5"^^xsd:string) "(S)-6-hydroxynicotine:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.5"^^xsd:string) "6-hydroxy-L-nicotine:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(S)-6-hydroxynicotine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.5"^^xsd:string) Annotation( "RHEA:11883"^^xsd:string) "Catalysis of the reaction: (S)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "coenzyme F420-independent methylene-H4MPT dehydrogenase activity"^^xsd:string) AnnotationAssertion( "F420-independent methylene-H4MPT dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0353"^^xsd:string) "Catalysis of the reaction: N5,N10-methenyltetrahydromethanopterin + H2 = N5,N10-methylenetetrahydromethanopterin."^^xsd:string) AnnotationAssertion(rdfs:label "5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity"^^xsd:string) AnnotationAssertion( "F420-independent 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity"^^xsd:string) AnnotationAssertion( "coenzyme F420-independent 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0588"^^xsd:string) "Catalysis of the reaction: nitrilotriacetate + OH- = H+ + 2 e- + glyoxylate + iminodiacetate."^^xsd:string) AnnotationAssertion(rdfs:label "nitrilotriacetate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.99.4"^^xsd:string) "nicotine:acceptor 6-oxidoreductase (hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "nicotine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.4"^^xsd:string) "nicotine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.4"^^xsd:string) "Catalysis of the reaction: nicotine + acceptor + H2O = (S)-6-hydroxynicotine + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.4"^^xsd:string) "D-nicotine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.4"^^xsd:string) "nicotine:(acceptor) 6-oxidoreductase (hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.99.11"^^xsd:string) "N(5),N(10)-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.11"^^xsd:string) "5-methyltetrahydromethanopterin:coenzyme-F420 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.11"^^xsd:string) "5,10-methylenetetrahydromethanopterin cyclohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.11"^^xsd:string) "5,10-methylenetetrahydromethanopterin reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.11"^^xsd:string) "N5,N10-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.11"^^xsd:string) "methylene-H4MPT reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.11"^^xsd:string) "N(5),N(10)-methylenetetrahydromethanopterin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.11"^^xsd:string) Annotation( "RHEA:21147"^^xsd:string) "Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme F420 + H(+) = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.11"^^xsd:string) "coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.11"^^xsd:string) "methylene-H(4)MPT reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.11"^^xsd:string) "N5,N10-methylenetetrahydromethanopterin reductase activity"^^xsd:string) AnnotationAssertion( "methylenetetrahydromethanopterin reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:9555888"^^xsd:string) "Catalysis of the generic reaction: epoxide + CO2 + NAD+ + electron donor = beta-keto acid + NADH + reduced electron donor; the electron donor may be NADPH or a dithiol. This reaction is the ring opening and carboxylation of an epoxide; for example: epoxypropane + CO2 + NAD+ + NADPH = acetoacetate + NADH + NADP+."^^xsd:string) AnnotationAssertion(rdfs:label "epoxide carboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.6.5.6"^^xsd:string) Annotation( "RHEA:23491"^^xsd:string) "Catalysis of the reaction: 1,4-benzoquinone + H(+) + NADPH = hydroquinone + NADP(+)."^^xsd:string) AnnotationAssertion(rdfs:label "p-benzoquinone reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.6"^^xsd:string) "NADPH:p-benzoquinone oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,3-dihydroxy DDT 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0452"^^xsd:string) "Catalysis of the reaction: 2,3-dihydroxy DDT + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-amino-2-nitroso-6-nitrotoluene reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0464"^^xsd:string) "Catalysis of the reaction: 4-amino-2-hydroxylamino-6-nitrotoluene + NADP+ = NADPH + H+ + 4-amino-2-nitroso-6-nitrotoluene."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "4-carboxy-4'-sulphoazobenzene reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-carboxy-4'-sulfoazobenzene reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0543"^^xsd:string) "Catalysis of the reaction: 4-carboxy-4'-sulfoazobenzene + 4 H+ + 4 e- = 4-aminobenzoate + 4-aminobenzenesulfonate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NAD(P)H nitroreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0346"^^xsd:string) "Catalysis of the conversion of a nitrate group to an amino or hydroxylamino group on toluene or a toluene derivative."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nitrobenzene nitroreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8815"^^xsd:string) "Catalysis of the reaction: nitrobenzene + 2 NADPH + 2 H+ = hydroxyaminobenzene + 2 NADP+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "NG reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nitroglycerin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0038"^^xsd:string) "Catalysis of the removal of one or more nitrite (NO2-) groups from nitroglycerin or a derivative."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0025"^^xsd:string) "Catalysis of the reaction: pentaerythritol trinitrate + NADPH = NADP+ + nitrate + pentaerythritol dinitrate."^^xsd:string) AnnotationAssertion(rdfs:label "pentaerythritol trinitrate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0028"^^xsd:string) "xenobiotic reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methanethiol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.3.4"^^xsd:string) "methyl mercaptan oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.3.4"^^xsd:string) "methylmercaptan oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.3.4"^^xsd:string) "methanethiol:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.3.4"^^xsd:string) "MT-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.3.4"^^xsd:string) "Catalysis of the reaction: methanethiol + O2 + H2O = formaldehyde + hydrogen sulfide + hydrogen peroxide."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.3.4"^^xsd:string) "(MM)-oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tetrachloro-p-hydroquinone reductive dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0314"^^xsd:string) "Catalysis of the reaction: 2,3,5,6-tetrachlorohydroquinone + 2 glutathione = 2,3,6-trichlorohydroquinone + glutathione disulfide + HCl."^^xsd:string) AnnotationAssertion( "tetrachlorohydroquinone reductive dehalogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "hydrogensulphite reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.3"^^xsd:string) "desulfoviridin activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.3"^^xsd:string) "trithionate:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.3"^^xsd:string) "bisulfite reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.3"^^xsd:string) "desulforubidin activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.3"^^xsd:string) "dissimilatory-type sulfite reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.3"^^xsd:string) "trithionate:(acceptor) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.3"^^xsd:string) "Catalysis of the reaction: trithionate + acceptor + 2 H2O + OH- = 3 HSO3- + reduced acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "hydrogensulfite reductase activity"^^xsd:string) AnnotationAssertion( "dissimilatory sulfite reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.99.3"^^xsd:string) "desulfofuscidin activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-(2,3-dihydroxyphenyl)propionate 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0309"^^xsd:string) "Catalysis of the reaction: 3-(2,3-dihydroxyphenyl)propionate + O2 = 2-hydroxy-6-keto-nona-2,4-dienedioate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1,2-dihydroxynaphthalene dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0255"^^xsd:string) "Catalysis of the reaction: 1,2-dihydroxynaphthalene + O2 = 2-hydroxychromene-2-carboxylate. C6 of the substrate molecular may have an NH2 group attached."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0455"^^xsd:string) "Catalysis of the reaction: phenanthrene + NADH + H+ + O2 = NAD+ + cis-3,4-dihydroxy-3,4-dihydrophenanthrene."^^xsd:string) AnnotationAssertion(rdfs:label "phenanthrene dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,2',3-trihydroxybiphenyl dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0032"^^xsd:string) "Catalysis of the reaction: 2,3-dihydroxybenzenoid + O2 = H+ + distal extradiol ring cleavage. Substrates are 2,2',3-trihydroxybiphenyl (forms 2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate) and 2,2',3-trihydroxydiphenylether (forms 2,3-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0422"^^xsd:string) "Catalysis of the reaction: 1,2-dihydroxyfluorene + O2 = 2-hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene) but-2-enoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0049"^^xsd:string) "Catalysis of the reaction: 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 = 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0442"^^xsd:string) "Catalysis of the reaction: 1,1-dichloro-2-(dihydroxy-4'-chorophenyl)-2-(4-chlorophenyl)ethene + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate."^^xsd:string) AnnotationAssertion(rdfs:label "1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion( "1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethylene 1,2-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protocatechuate 3,4-dioxygenase type II activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0581"^^xsd:string) "Catalysis of the reaction: 4-sulfocatechol + O2 = 3-sulfomuconate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0457"^^xsd:string) "Catalysis of the reaction: 2'-aminobiphenyl-2,3-diol + O2 = H+ + 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0415"^^xsd:string) "Catalysis of the reaction: 3,4-dihydroxyfluorene + O2 = 2-hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene) but-2-enoic acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0310"^^xsd:string) "Catalysis of the reaction: 2,3-dihydroxyethylbenzene + O2 = H+ + 2-hydroxy-6-oxoocta-2,4-dienoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "carbazole 1,9alpha-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0456"^^xsd:string) "Catalysis of the reaction: carbazole + NADH + O2 + H+ = NAD+ + 2'-aminobiphenyl-2,3-diol."^^xsd:string) AnnotationAssertion(rdfs:label "carbazole 1,9a-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0162"^^xsd:string) "Catalysis of the reaction: 1,2-dihydroxydibenzothiophene + O2 = cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate."^^xsd:string) AnnotationAssertion(rdfs:label "dihydroxydibenzothiophene dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity"^^xsd:string) AnnotationAssertion( "1,2-dihydroxynaphthalene-6-sulphonate 1,8a-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0324"^^xsd:string) "Catalysis of the reaction: 1,2-dihydroxynaphthalene-6-sulfonate + O2 = H+ + (Z)-4-(2-hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "styrene dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0256"^^xsd:string) "Catalysis of the reaction: styrene + O2 + NADH + H+ = NAD+ + styrene cis-glycol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0501"^^xsd:string) "Catalysis of the reaction: 3,4-dihydroxyphenanthrene + O2 = H+ + 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate."^^xsd:string) AnnotationAssertion(rdfs:label "3,4-dihydroxyphenanthrene dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroquinone 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0228"^^xsd:string) "Catalysis of the reaction: hydroquinone + O2 = cis,trans-4-hydroxymuconic semialdehyde."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0395"^^xsd:string) "Catalysis of the reaction: p-cumate + NADH + H+ + O2 = NAD+ + cis-2,3-dihydroxy-2,3-dihydro-p-cumate."^^xsd:string) AnnotationAssertion(rdfs:label "p-cumate 2,3-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-666"^^xsd:string) Annotation( "UM-BBD_reactionID:r0397"^^xsd:string) "Catalysis of the reaction: 2,3-dihydroxy-p-cumate + O2 = 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate."^^xsd:string) AnnotationAssertion( "2,3-dihydroxy-p-cumate 3,4-dioxygenase"^^xsd:string) AnnotationAssertion(rdfs:label "2,3-dihydroxy-p-cumate dioxygenase activity"^^xsd:string) AnnotationAssertion( "2,3-dihydroxy-p-cumate-3,4-dioxygenase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3,5-dichlorocatechol 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0276"^^xsd:string) "Catalysis of the reaction: 3,5-dichlorocatechol + O2 = 2 H+ + 2,4-dichloro-cis,cis-muconate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0305"^^xsd:string) "Catalysis of the reaction: 2-aminophenol + O2 = 2-aminomuconic semialdehyde."^^xsd:string) AnnotationAssertion(rdfs:label "2-aminophenol 1,6-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0422"^^xsd:string) "Catalysis of the reaction: 2,6-dichlorohydroquinone + O2 + H2O = HCl + 2 H+ + 2-chloromaleylacetate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0655"^^xsd:string) "Catalysis of the reaction: 3,6-dichlorocatechol + O2 = 2 H+ + 2,5-dichloro-cis,cis-muconate."^^xsd:string) AnnotationAssertion(rdfs:label "chlorocatechol 1,2-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.1"^^xsd:string) "catechol:oxygen 1,2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.1"^^xsd:string) "catechol 1,2-oxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "catechol 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.1"^^xsd:string) "catechase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.1"^^xsd:string) "Catalysis of the reaction: catechol + O2 = cis,cis-muconate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.1"^^xsd:string) "1,2-pyrocatechase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.1"^^xsd:string) "CD II"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.1"^^xsd:string) "pyrocatechol 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.1"^^xsd:string) "catechol-oxygen 1,2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.1"^^xsd:string) "CD I"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.1"^^xsd:string) "pyrocatechase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.2"^^xsd:string) "Catalysis of the reaction: catechol + O2 = 2-hydroxymuconate semialdehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.2"^^xsd:string) "catechol oxygenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.2"^^xsd:string) "catechol:oxygen 2,3-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(rdfs:label "catechol 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.2"^^xsd:string) "catechol 2,3-oxygenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.2"^^xsd:string) "metapyrocatechase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.2"^^xsd:string) "cato2ase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.2"^^xsd:string) "2,3-pyrocatechase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.2"^^xsd:string) "pyrocatechol 2,3-dioxygenase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protocatechuate 3,4-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.3"^^xsd:string) "protocatechuic acid oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.3"^^xsd:string) "Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.3"^^xsd:string) "protocatechuate oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.3"^^xsd:string) "protocatechuic 3,4-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.3"^^xsd:string) "protocatechuic 3,4-oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.3"^^xsd:string) "protocatechuate:oxygen 3,4-oxidoreductase (decyclizing)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.8"^^xsd:string) "protocatechuic 4,5-oxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protocatechuate 4,5-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.8"^^xsd:string) "protocatechuate 4,5-oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.8"^^xsd:string) "Catalysis of the reaction: protocatechuate + O2 = 4-carboxy-2-hydroxymuconate semialdehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.8"^^xsd:string) "protocatechuate:oxygen 4,5-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.8"^^xsd:string) "protocatechuic 4,5-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.12.16"^^xsd:string) Annotation( "RHEA:28770"^^xsd:string) "Catalysis of the reaction: ethylnitronate + O(2) = acetaldehyde + nitrite."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.16"^^xsd:string) Annotation( ) "nitronate:oxygen 2-oxidoreductase (nitrite-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.32"^^xsd:string) "2-nitropropane dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nitronate monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.37"^^xsd:string) "benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(rdfs:label "hydroxyquinol 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.37"^^xsd:string) "hydroxyquinol dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.37"^^xsd:string) "Catalysis of the reaction: benzene-1,2,4-triol + O2 = 3-hydroxy-cis,cis-muconate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "1-hydroxy-2-naphthoate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.38"^^xsd:string) "Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 = (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate."^^xsd:string) AnnotationAssertion(rdfs:label "1-hydroxy-2-naphthoate 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.38"^^xsd:string) "1-hydroxy-2-naphthoate:oxygen 1,2-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.38"^^xsd:string) "1-hydroxy-2-naphthoate-degrading enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.38"^^xsd:string) "1-hydroxy-2-naphthoic acid dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.39"^^xsd:string) "2,3-dihydroxybiphenyl dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.39"^^xsd:string) "biphenyl-2,3-diol:oxygen 1,2-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.39"^^xsd:string) "biphenyl-2,3-diol dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "biphenyl-2,3-diol 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.39"^^xsd:string) "Catalysis of the reaction: biphenyl-2,3-diol + O2 = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O."^^xsd:string) AnnotationAssertion( "2,3-dihydroxybiphenyl 1,2-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,4,5-trichlorophenoxyacetic acid oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0359"^^xsd:string) "Catalysis of the reaction: 2,4,5-trichlorophenoxyacetic acid + 1/2 O2 = glyoxylate + 2,4,5-trichlorophenol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0407"^^xsd:string) "Catalysis of the reaction: fluorene + 2 H+ + 2 e- + O2 = H2O + 9-fluorenol."^^xsd:string) AnnotationAssertion(rdfs:label "fluorene oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0647"^^xsd:string) "Catalysis of the reaction: butyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyltin."^^xsd:string) AnnotationAssertion(rdfs:label "mono-butyltin dioxygenase activity"^^xsd:string) AnnotationAssertion( "MBT dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "TBT dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0643"^^xsd:string) "Catalysis of the reaction: tri-n-butyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyldibutyltin."^^xsd:string) AnnotationAssertion(rdfs:label "tri-n-butyltin dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0645"^^xsd:string) "Catalysis of the reaction: dibutyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutylbutyltin."^^xsd:string) AnnotationAssertion( "DBT dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "di-n-butyltin dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0640"^^xsd:string) "Catalysis of the reaction: methylsilanetriol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylsilanetriol."^^xsd:string) AnnotationAssertion(rdfs:label "methylsilanetriol hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methyl tertiary butyl ether 3-monooxygenase activity"^^xsd:string) AnnotationAssertion( "MTBE 3-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1023"^^xsd:string) "Catalysis of the reaction: methyl tert-butyl ether + 1/2 O2 = tert-butyl alcohol + formaldehyde."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-nitrocatechol 4-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0231"^^xsd:string) "Catalysis of the reaction: 4-nitrocatechol + O2 + 4 e- + 3 H+ = H2O + nitrite + 1,2,4-benzenetriol."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-chlorophenoxyacetate monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0281"^^xsd:string) "Catalysis of the reaction: 4-chlorophenoxyacetate + 1/2 O2 = glyoxylate + 4-chlorophenol."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "tert-butyl alcohol 2-monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tert-butanol 2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0615"^^xsd:string) "Catalysis of the reaction: tert-butanol + 1/2 O2 = 2-methyl-2-hydroxy-1-propanol."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0716"^^xsd:string) "Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + pinocarveol."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-pinene monooxygenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "DMSD hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0637"^^xsd:string) "Catalysis of the reaction: dimethylsilanediol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylmethylsilanediol."^^xsd:string) AnnotationAssertion(rdfs:label "dimethylsilanediol hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ammonia monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16347810"^^xsd:string) "Catalysis of the oxidation of alkanes (up to C8) to alcohols and alkenes (up to C5) to epoxides and alcohols in the presence of ammonium ions."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroxymethylsilanetriol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0641"^^xsd:string) "Catalysis of the reaction: hydroxymethylsilanetriol + O2 + 2 H+ + 2 e- = 2 H2O + formylsilanetriol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0619"^^xsd:string) "Catalysis of the reaction: 2-hydroxyisobutyrate + 1/2 O2 = 2,3-dihydroxy-2-methyl propionate."^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxyisobutyrate 3-monooxygenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-pinene dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0709"^^xsd:string) "Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + myrtenol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.29"^^xsd:string) Annotation( "RHEA:12571"^^xsd:string) "Catalysis of the reaction: 4-nitrophenol + H(+) + NADH + O(2) = 4-nitrocatechol + H(2)O + NAD(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.29"^^xsd:string) "4-nitrophenol-2-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-nitrophenol 2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.29"^^xsd:string) "4-nitrophenol,NADH:oxygen oxidoreductase (2-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.29"^^xsd:string) "4-nitrophenol hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0274"^^xsd:string) "Catalysis of the reaction: 2,4-dichlorophenoxyacetate + 2-oxoglutarate + oxygen = 2,4-dichlorophenol + glyoxylate + succinate + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0306"^^xsd:string) "Catalysis of the reaction: nitrobenzene + NADH + O2 = NAD+ + nitrite + catechol."^^xsd:string) AnnotationAssertion(rdfs:label "nitrobenzene 1,2-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-aminobenzoate 3,4-dioxygenase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0566"^^xsd:string) "Catalysis of the reaction: 4-aminobenzoate + 2 H+ + O2 + 2 e- = NH3 + 3,4-dihydroxybenzoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0295"^^xsd:string) "Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 + H+ = NAD+ + HSO3(-) + 4-methylcatechol."^^xsd:string) AnnotationAssertion(rdfs:label "benzenesulfonate dioxygenase activity"^^xsd:string) AnnotationAssertion( "benzenesulphonate dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1-indanone monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0417"^^xsd:string) "Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3,4-dihydrocoumarin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0416"^^xsd:string) "Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3-hydroxy-1-indanone."^^xsd:string) AnnotationAssertion(rdfs:label "1-indanone dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chlorobenzene dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0062"^^xsd:string) "Catalysis of the reaction: 2,3-unsubstituted benzenoid + O2 + NAD(P)H + H+ = 2,3-cis-dihydroxydihydrobenzenoid + NAD(P)+. Substrates include 1,4-dichlorobenzene (forms 3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene), 1,2,3,4-tetrachlorobenzene (forms cis-chlorobenzene dihydrodiol) and 1,2,4-trichlorobenzene (forms 3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:R606-RXN"^^xsd:string) "Catalysis of the reaction: dibenzofuran + NADH + H+ + O2 = 2,2',3-trihydroxybiphenyl + NAD+."^^xsd:string) AnnotationAssertion(rdfs:label "dibenzofuran 4,4a-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "toluate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0190"^^xsd:string) "Catalysis of the reaction: methylbenzoate + NADH + O2 + H+ = NAD+ + 1,2-dihydroxymethylcyclohexa-3,5-dienecarboxylate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dibenzothiophene dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0160"^^xsd:string) "Catalysis of the reaction: dibenzothiophene + NADH + O2 + H+ = NAD+ + cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0409"^^xsd:string) "Catalysis of the reaction: 9-fluorenone + 2 NADPH + O2 = 2 NADP+ + 3,4-dihydroxy-3,4-dihydro-9-fluorenone."^^xsd:string) AnnotationAssertion(rdfs:label "9-fluorenone dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0247"^^xsd:string) "Catalysis of the reaction: ethylbenzene + O2 + NADH + H+ = NAD+ + cis-2,3-dihydroxy-2,3-dihydroethylbenzene."^^xsd:string) AnnotationAssertion(rdfs:label "ethylbenzene dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-indanone monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0424"^^xsd:string) "Catalysis of the reaction: 2-indanone + NADPH + 1/2 O2 = NADP+ + 3-isochromanone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:R305-RXN"^^xsd:string) Annotation( "UM-BBD_reactionID:r0093"^^xsd:string) "Catalysis of the reaction: 2,3,5-trihydroxytoluene + O2 = 2,4,6-trioxoheptanoate."^^xsd:string) AnnotationAssertion(rdfs:label "trihydroxytoluene dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0580"^^xsd:string) "Catalysis of the reaction: 4-aminobenzenesulfonate + 2 H+ + O2 + 2 e- = NH3 + 4-sulfocatechol."^^xsd:string) AnnotationAssertion( "4-aminobenzenesulphonate 3,4-dioxygenase (deaminating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-aminobenzenesulfonate 3,4-dioxygenase (deaminating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.12.1"^^xsd:string) "Catalysis of the reaction: anthranilate + NADPH + H+ + O2 = catechol + CO2 + NADP+ + NH3."^^xsd:string) AnnotationAssertion( "anthranilate dioxygenase reductase"^^xsd:string) AnnotationAssertion( "anthranilate 1,2-dioxygenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.1"^^xsd:string) "anthranilate hydroxylase activity"^^xsd:string) AnnotationAssertion( "AntA"^^xsd:string) AnnotationAssertion(rdfs:label "anthranilate 1,2-dioxygenase (deaminating, decarboxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.1"^^xsd:string) "anthranilic acid hydroxylase activity"^^xsd:string) AnnotationAssertion( "AntC"^^xsd:string) AnnotationAssertion( "anthranilate dioxygenase activity"^^xsd:string) AnnotationAssertion( "AntB"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.1"^^xsd:string) "anthranilate,NAD(P)H:oxygen oxidoreductase (1,2-hydroxylating, deaminating, decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.1"^^xsd:string) "anthranilic hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.12.3"^^xsd:string) "benzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.3"^^xsd:string) "benzene dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.3"^^xsd:string) "benzene hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.3"^^xsd:string) Annotation( "RHEA:13816"^^xsd:string) "Catalysis of the reaction: benzene + H(+) + NADH + O(2) = cis-cyclohexa-3,5-diene-1,2-diol + NAD(+)."^^xsd:string) AnnotationAssertion(rdfs:label "benzene 1,2-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.12.7"^^xsd:string) "phthalate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.7"^^xsd:string) "PDO activity"^^xsd:string) AnnotationAssertion(rdfs:label "phthalate 4,5-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.7"^^xsd:string) Annotation( "RHEA:17492"^^xsd:string) "Catalysis of the reaction: H(+) + NADH + O(2) + phthalate = cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.7"^^xsd:string) "phthalate,NADH:oxygen oxidoreductase (4,5-hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.12.8"^^xsd:string) "4-sulfobenzoate,NADH:oxygen oxidoreductase (3,4-hydroxylating, sulfite-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.8"^^xsd:string) Annotation( "RHEA:13940"^^xsd:string) "Catalysis of the reaction: 4-sulfobenzoate + H(+) + NADH + O(2) = 3,4-dihydroxybenzoate + NAD(+) + sulfite."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.8"^^xsd:string) "4-sulfobenzoate 3,4-dioxygenase system"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.8"^^xsd:string) "4-sulfobenzoate dioxygenase activity"^^xsd:string) AnnotationAssertion( "4-sulphobenzoate 3,4-dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-sulfobenzoate 3,4-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-chlorophenylacetate 3,4-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.9"^^xsd:string) Annotation( "RHEA:14692"^^xsd:string) "Catalysis of the reaction: 4-chlorophenylacetate + NADH + O(2) = 3,4-dihydroxyphenylacetate + chloride + NAD(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.9"^^xsd:string) "4-chlorophenylacetate,NADH:oxygen oxidoreductase (3,4-hydroxylating, dechlorinating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.12.10"^^xsd:string) "benzoic hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.10"^^xsd:string) "benzoate hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.10"^^xsd:string) "benzoate dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "benzoate 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.10"^^xsd:string) "benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.10"^^xsd:string) "Catalysis of the reaction: benzoate + NADH + H+ + O2 = catechol + CO2 + NAD+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.10"^^xsd:string) "benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, decarboxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.12.11"^^xsd:string) Annotation( "RHEA:16740"^^xsd:string) "Catalysis of the reaction: H(+) + NADH + O(2) + toluene = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.11"^^xsd:string) "toluene,NADH:oxygen oxidoreductase (1,2-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.11"^^xsd:string) "toluene 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "toluene dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.11"^^xsd:string) "toluene 2,3-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.12.12"^^xsd:string) "naphthalene,NADH:oxygen oxidoreductase (1,2-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.12"^^xsd:string) "naphthalene dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "naphthalene 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.12"^^xsd:string) "naphthalene oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.12"^^xsd:string) "Catalysis of the reaction: naphthalene + NADH + H+ + O2 = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.12.13"^^xsd:string) "Catalysis of the reaction: 2-chlorobenzoate + NADH + H+ + O2 = catechol + chloride + NAD+ + CO2."^^xsd:string) AnnotationAssertion( "2-halobenzoate 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-chlorobenzoate 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.13"^^xsd:string) "2-chlorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, dechlorinating, decarboxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2-aminobenzenesulphonate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.14"^^xsd:string) "2-aminobenzenesulfonate,NADH:oxygen oxidoreductase (2,3-hydroxylating, ammonia-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "2-aminobenzenesulfonate 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.14"^^xsd:string) "2-aminosulfobenzene 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion( "2-aminobenzenesulfonate dioxygenase activity"^^xsd:string) AnnotationAssertion( "2-aminobenzenesulphonate 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.14"^^xsd:string) Annotation( "RHEA:23471"^^xsd:string) "Catalysis of the reaction: 2-aminobenzenesulfonate + 2 H(+) + NADH + O(2) = 2,3-dihydroxybenzenesulfonate + NAD(+) + NH(4)(+). 2,3-dihydroxybenzenesulfonate is also known as 3-sulfocatechol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "terephthalate 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.15"^^xsd:string) "benzene-1,4-dicarboxylate,NADH:oxygen oxidoreductase (1,2-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.15"^^xsd:string) Annotation( "RHEA:10315"^^xsd:string) "Catalysis of the reaction: H(+) + NADH + O(2) + terephthalate = (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.15"^^xsd:string) "benzene-1,4-dicarboxylate 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.15"^^xsd:string) "1,4-dicarboxybenzoate 1,2-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.12.16"^^xsd:string) "Catalysis of the reaction: quinolin-2-ol + NADH + H+ + O2 = 2,5,6-trihydroxy-5,6-dihydroquinoline + NAD+."^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxyquinoline 5,6-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.16"^^xsd:string) "quinolin-2-ol,NADH:oxygen oxidoreductase (5,6-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.16"^^xsd:string) "quinolin-2(1H)-one 5,6-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.16"^^xsd:string) "quinolin-2-ol 5,6-dioxygenase activity"^^xsd:string) AnnotationAssertion( "2-oxo-1,2-dihydroquinoline 5,6-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0081"^^xsd:string) "Catalysis of the reaction: 3-hydroxytoluene + NADH + O2 = NAD+ + OH- + 3-hydroxybenzyl alcohol."^^xsd:string) AnnotationAssertion(rdfs:label "3,5-xylenol methylhydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0036"^^xsd:string) "Catalysis of the reaction: phenylacetate + NADH + O2 = NAD+ + OH- + 2-hydroxyphenylacetate."^^xsd:string) AnnotationAssertion(rdfs:label "phenylacetate hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0226"^^xsd:string) "Catalysis of the reaction: p-nitrophenol + O2 + NADPH = H2O + NADP+ + nitrite + p-benzoquinone."^^xsd:string) AnnotationAssertion(rdfs:label "4-nitrophenol 4-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "dimethyl sulphide monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dimethyl sulfide monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0208"^^xsd:string) "Catalysis of the reaction: dimethyl sulfide + NADH + O2 = NAD+ + OH- + methanethiol + formaldehyde."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0742"^^xsd:string) "Catalysis of the reaction: alpha-pinene + NADH + H+ + O2 = NAD+ + H2O + alpha-pinene oxide."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-pinene monooxygenase [NADH] activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0462"^^xsd:string) "Catalysis of the reaction: (4R)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4R)-limonene-1,2-epoxide."^^xsd:string) AnnotationAssertion(rdfs:label "(R)-limonene 1,2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.107"^^xsd:string) "(+)-limonene 1,2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.107"^^xsd:string) Annotation( ) "(+)-limonene,NAD(P)H:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.107"^^xsd:string) Annotation( ) "(R)-limonene,NAD(P)H:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0495"^^xsd:string) "Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-9,10-oxide."^^xsd:string) AnnotationAssertion(rdfs:label "phenanthrene 9,10-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0491"^^xsd:string) "Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 + NADPH + 2 H+ = NADP+ + H2O + CO2 + 1,2-dihydroxynaphthalene."^^xsd:string) AnnotationAssertion(rdfs:label "1-hydroxy-2-naphthoate hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0225"^^xsd:string) "Catalysis of the reaction: toluene + 1/2 O2 = 4-hydroxytoluene."^^xsd:string) AnnotationAssertion(rdfs:label "toluene 4-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "xylene monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0172"^^xsd:string) "Catalysis of the reactions: toluene + 1/2 O2 = benzyl alcohol, and xylene + 1/2 O2 = methylbenzyl alcohol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-621"^^xsd:string) "Catalysis of the reaction: dibenzothiophene + NADH + H+ + O2 = dibenzothiophene-5-oxide + NAD+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "dibenzothiophene monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0048"^^xsd:string) "Catalysis of the reaction: 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0252"^^xsd:string) "Catalysis of the addition or substitution of an OH group on C4 of a halogenated phenol."^^xsd:string) AnnotationAssertion(rdfs:label "chlorophenol 4-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carbon disulfide oxygenase activity"^^xsd:string) AnnotationAssertion( "carbon disulphide oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0599"^^xsd:string) "Catalysis of the reaction: carbon disulfide + NADH + H+ + O2 = [S] + H2O + NAD+ + carbonyl sulfide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0222"^^xsd:string) "Catalysis of the reaction: toluene + 1/2 O2 = 2-hydroxytoluene."^^xsd:string) AnnotationAssertion(rdfs:label "toluene 2-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.69"^^xsd:string) "Catalysis of the reaction: propene + NADH + H+ + O2 = 1,2-epoxypropane + NAD+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.69"^^xsd:string) "alkene epoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.69"^^xsd:string) "alkene,NADH:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alkene monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1-hydroxy-2-oxolimonene 1,2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0736"^^xsd:string) "Catalysis of the reaction: (1S,4R)-1-hydroxy-2-oxolimonene + NADPH + O2 = NADP+ + OH- + (3R)-3-isopropenyl-6-oxoheptanoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0333"^^xsd:string) "Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-1,2-oxide."^^xsd:string) AnnotationAssertion(rdfs:label "phenanthrene 1,2-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.111"^^xsd:string) "methanesulfonate,FMNH2:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "methanesulphonic acid monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.111"^^xsd:string) "MSAMO activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.111"^^xsd:string) "methanesulfonic acid monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.111"^^xsd:string) Annotation( ) "methanesulfonate,NADH:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methanesulfonate monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.111"^^xsd:string) "MSA monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.111"^^xsd:string) "mesylate monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.111"^^xsd:string) "Catalysis of the reaction: methanesulfonate + NADH + H+ + O2 = formaldehyde + NAD+ + sulfite + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tetrahydrofuran hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0017"^^xsd:string) "Catalysis of the reaction: tetrahydrofuran + O2 + 2 H+ + 2 e- = H2O + 2-hydroxytetrahydrofuran."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "styrene monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0225"^^xsd:string) "Catalysis of the reaction: styrene + NADPH + FADH + O2 = NADP+ + FAD+ + H2O + styrene oxide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0296"^^xsd:string) "Catalysis of the reaction: toluene-4-sulfonate + 1/2 O2 + H+ = HSO3(-) + 4-hydroxytoluene."^^xsd:string) AnnotationAssertion(rdfs:label "toluene-4-sulfonate monooxygenase activity"^^xsd:string) AnnotationAssertion( "toluene-4-sulphonate monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0290"^^xsd:string) "Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 = NAD+ + OH- + 4-sulfobenzyl alcohol."^^xsd:string) AnnotationAssertion(rdfs:label "toluene-sulfonate methyl-monooxygenase activity"^^xsd:string) AnnotationAssertion( "toluene-sulphonate methyl-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.-"^^xsd:string) "Catalysis of the reaction: 3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxy-phenylacetate hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0252"^^xsd:string) "Catalysis of the reaction: 2-hydroxyphenylacetate + NADH + O2 = NAD+ + OH- + homogentisate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0430"^^xsd:string) "Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA + NADH + H+ + O2 = NAD+ + H2O + delta2,5-3,4,4-trimethylpimelyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0508"^^xsd:string) "Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-3,4-oxide."^^xsd:string) AnnotationAssertion(rdfs:label "phenanthrene 3,4-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "toluene 3-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0224"^^xsd:string) "Catalysis of the reaction: toluene + 1/2 O2 = 3-hydroxytoluene."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.1"^^xsd:string) "salicylic hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.1"^^xsd:string) "salicylate monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.1"^^xsd:string) "salicylate 1-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.1"^^xsd:string) "salicylate,NADH:oxygen oxidoreductase (1-hydroxylating, decarboxylating)"^^xsd:string) AnnotationAssertion( "salicylate hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.1"^^xsd:string) "Catalysis of the reaction: salicylate + NADH + H+ + O2 = catechol + NAD+ + H2O + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "salicylate 1-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.1"^^xsd:string) "salicylate hydroxylase (decarboxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.2"^^xsd:string) "4-hydroxybenzoate,NADPH:oxygen oxidoreductase (3-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.2"^^xsd:string) "4-hydroxybenzoate monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.2"^^xsd:string) "Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = protocatechuate + NADP+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.2"^^xsd:string) "p-hydroxybenzoic acid hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.2"^^xsd:string) "p-hydroxybenzoate hydrolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.2"^^xsd:string) "para-hydroxybenzoate hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.2"^^xsd:string) "4-hydroxybenzoate 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.2"^^xsd:string) "p-hydroxybenzoate hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.2"^^xsd:string) "p-hydroxybenzoic acid hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.2"^^xsd:string) "p-hydroxybenzoate-3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.2"^^xsd:string) "p-hydroxybenzoic hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxybenzoate 3-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.3"^^xsd:string) "4 HPA 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R02698"^^xsd:string) "Catalysis of the reaction: 4-hydroxyphenylacetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + NAD+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.3"^^xsd:string) "p-hydroxyphenylacetate 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.3"^^xsd:string) "p-hydroxyphenylacetate hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.3"^^xsd:string) "4-hydroxyphenylacetate 3-monooxygenase activity"^^xsd:string) AnnotationAssertion( "4-hydroxyphenylacetate 3-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.6"^^xsd:string) Annotation( "RHEA:19604"^^xsd:string) "Catalysis of the reaction: H(+) + NADH + O(2) + orcinol = 2,3,5-trihydroxytoluene + H(2)O + NAD(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.6"^^xsd:string) "orcinol,NADH:oxygen oxidoreductase (2-hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "orcinol 2-monooxygenase activity"^^xsd:string) AnnotationAssertion( "orcinol hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.7"^^xsd:string) "phenol,NADPH:oxygen oxidoreductase (2-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.7"^^xsd:string) "phenol hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phenol 2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.7"^^xsd:string) "Catalysis of the reaction: phenol + NADPH + H+ + O2 = catechol + NADP+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.7"^^xsd:string) "phenol o-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,6-dihydroxypyridine 3-monooxygenase activity"^^xsd:string) AnnotationAssertion( "2,6-dihydroxypyridine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.10"^^xsd:string) Annotation( "RHEA:16920"^^xsd:string) "Catalysis of the reaction: 2,6-dihydroxypyridine + H(+) + NADH + O(2) = 2,3,6-trihydroxypyridine + H(2)O + NAD(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.10"^^xsd:string) "2,6-dihydroxypyridine,NADH:oxygen oxidoreductase (3-hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.12"^^xsd:string) "benzoate,NADPH:oxygen oxidoreductase (4-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.12"^^xsd:string) "p-hydroxybenzoate hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.12"^^xsd:string) "benzoic acid 4-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.12"^^xsd:string) "benzoate 4-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.12"^^xsd:string) "benzoic 4-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.12"^^xsd:string) "benzoate-para-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "benzoate 4-monooxygenase activity"^^xsd:string) AnnotationAssertion( "4-hydroxybenzoic hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.12"^^xsd:string) Annotation( "RHEA:18036"^^xsd:string) "Catalysis of the reaction: benzoate + H(+) + NADPH + O(2) = 4-hydroxybenzoate + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.12"^^xsd:string) "benzoate-p-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.18"^^xsd:string) "4-hydroxyphenylacetic 1-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.18"^^xsd:string) "4-HPA 1-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.18"^^xsd:string) "4-hydroxyphenylacetate 1-hydroxylase activity"^^xsd:string) AnnotationAssertion( "4-hydroxyphenyl-acetate 1-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.18"^^xsd:string) "Catalysis of the reaction: 4-hydroxyphenylacetate + NADPH + H+ + O2 = homogentisate + NADP+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxyphenylacetate 1-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.18"^^xsd:string) "4-hydroxyphenylacetate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.20"^^xsd:string) "2,4-dichlorophenol,NADPH:oxygen oxidoreductase (6-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.20"^^xsd:string) "Catalysis of the reaction: 2,4-dichlorophenol + NADPH + H+ + O2 = 3,5-dichlorocatechol + NADP+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "2,4-dichlorophenol 6-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.20"^^xsd:string) "2,4-dichlorophenol monooxygenase activity"^^xsd:string) AnnotationAssertion( "2,4-dichlorophenol hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.22"^^xsd:string) "cyclohexanone:NADPH:oxygen oxidoreductase (lactone-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.22"^^xsd:string) "Catalysis of the reaction: cyclohexanone + NADPH + H+ + O2 = 6-hexanolide + NADP+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.22"^^xsd:string) "cyclohexanone oxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyclohexanone monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.22"^^xsd:string) "cyclohexanone:NADPH:oxygen oxidoreductase (6-hydroxylating, 1,2-lactonizing) activity"^^xsd:string) AnnotationAssertion( "cyclohexanone 1,2-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.23"^^xsd:string) "3-hydroxybenzoate,NADPH:oxygen oxidoreductase (4-hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxybenzoate 4-monooxygenase activity"^^xsd:string) AnnotationAssertion( "3-hydroxybenzoate 4-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.23"^^xsd:string) Annotation( "RHEA:11483"^^xsd:string) "Catalysis of the reaction: 3-hydroxybenzoate + H(+) + NADPH + O(2) = 3,4-dihydroxybenzoate + H(2)O + NADP(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-hydroxybenzoate 6-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.24"^^xsd:string) Annotation( "RHEA:22695"^^xsd:string) "Catalysis of the reaction: 3-hydroxybenzoate + H(+) + NADH + O(2) = 2,5-dihydroxybenzoate + H(2)O + NAD(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.24"^^xsd:string) "3-hydroxybenzoate,NADH:oxygen oxidoreductase (6-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.24"^^xsd:string) "3-hydroxybenzoic acid-6-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.24"^^xsd:string) "m-hydroxybenzoate 6-hydroxylase activity"^^xsd:string) AnnotationAssertion( "3-hydroxybenzoate 6-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.27"^^xsd:string) "4-aminobenzoate dehydrogenase activity"^^xsd:string) AnnotationAssertion( "4-aminobenzoate hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.27"^^xsd:string) "4-aminobenzoate monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-aminobenzoate 1-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.27"^^xsd:string) "4-aminobenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.27"^^xsd:string) "Catalysis of the reaction: 4-aminobenzoate + NADPH + H+ + O2 = 4-hydroxyaniline + NADP+ + H2O + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "4-hydroxybenzoate 3-monooxygenase (reduced nicotinamide adenine dinucleotide (phosphate))"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.33"^^xsd:string) "4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (3-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.33"^^xsd:string) "4-hydroxybenzoate-3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.33"^^xsd:string) "4-hydroxybenzoate 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.33"^^xsd:string) "Catalysis of the reaction: 4-hydroxybenzoate + NAD(P)H + H+ + O2 = 3,4-dihydroxybenzoate + NAD(P)+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.35"^^xsd:string) Annotation( "RHEA:21239"^^xsd:string) "Catalysis of the reaction: anthranilate + 2 H(+) + NADPH + O(2) = 2,3-dihydroxybenzoate + NADP(+) + NH(4)(+)."^^xsd:string) AnnotationAssertion( "anthranilate hydroxylase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.35"^^xsd:string) "anthranilate 2,3-hydroxylase (deaminating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "anthranilate 3-monooxygenase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.35"^^xsd:string) "anthranilate hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.35"^^xsd:string) "anthranilate,NADPH:oxygen oxidoreductase (3-hydroxylating, deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.35"^^xsd:string) "anthranilate 2,3-dioxygenase (deaminating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.40"^^xsd:string) "Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 NADPH + 2 H+ + O2 = 2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + 2 NADP+."^^xsd:string) AnnotationAssertion(rdfs:label "anthraniloyl-CoA monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.40"^^xsd:string) "2-aminobenzoyl-CoA,NAD(P)H:oxygen oxidoreductase (de-aromatizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.40"^^xsd:string) "2-aminobenzoyl-CoA monooxygenase/reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.40"^^xsd:string) "anthraniloyl coenzyme A reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.47"^^xsd:string) "(S)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating)"^^xsd:string) AnnotationAssertion( "(-)-limonene 3-monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(S)-limonene 3-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.47"^^xsd:string) Annotation( "RHEA:15132"^^xsd:string) "Catalysis of the reaction: (4S)-limonene + H(+) + NADPH + O(2) = (1S,6R)-isopiperitenol + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.47"^^xsd:string) "(-)-limonene 3-hydroxylase activity"^^xsd:string) AnnotationAssertion( "limonene 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.47"^^xsd:string) "(-)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "(-)-limonene 6-monooxygenase activity"^^xsd:string) AnnotationAssertion( "limonene 6-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(S)-limonene 6-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.48"^^xsd:string) "(S)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.48"^^xsd:string) "(-)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.48"^^xsd:string) "Catalysis of the reaction: (-)-limonene + NADPH + H+ + O2 = (-)-trans-carveol + NADP+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.48"^^xsd:string) "(-)-limonene 6-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.49"^^xsd:string) "(-)-limonene monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.49"^^xsd:string) "(-)-limonene,NADPH:oxygen oxidoreductase (7-hydroxylating) activity"^^xsd:string) AnnotationAssertion( "limonene hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.49"^^xsd:string) Annotation( "RHEA:23435"^^xsd:string) "Catalysis of the reaction: (4S)-limonene + H(+) + NADPH + O(2) = (4S)-perillyl alcohol + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.49"^^xsd:string) "(S)-limonene,NADPH:oxygen oxidoreductase (7-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.49"^^xsd:string) "(-)-limonene hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(S)-limonene 7-monooxygenase activity"^^xsd:string) AnnotationAssertion( "(-)-limonene 7-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pentachlorophenol monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.50"^^xsd:string) "PCB4MO activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.50"^^xsd:string) "pentachlorophenol dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.50"^^xsd:string) "pentachlorophenol dechlorinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.50"^^xsd:string) "pentachlorophenol,NADPH:oxygen oxidoreductase (hydroxylating, dechlorinating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.50"^^xsd:string) "PCB 4-monooxygenase activity"^^xsd:string) AnnotationAssertion( "pentachlorophenol 4-monooxygenase activity"^^xsd:string) AnnotationAssertion( "pentachlorophenol hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.50"^^xsd:string) "PcpB"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.50"^^xsd:string) "Catalysis of the reaction: pentachlorophenol + NADPH + H+ + O2 = tetrachlorohydroquinone + NADP+ + chloride."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.50"^^xsd:string) "PCP hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.64"^^xsd:string) "4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating)"^^xsd:string) AnnotationAssertion( "4-hydroxybenzoate 1-monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxybenzoate 1-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.64"^^xsd:string) "Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = hydroquinone + NADP+ + H2O + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dibenzothiophene-5,5-dioxide monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0235"^^xsd:string) "Catalysis of the reaction: dibenzothiophene-5,5-dioxide + O2 + 2 NADH + H+ = 2 NAD+ + H2O + 2'-hydroxybiphenyl-2-sulfinate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "deethylatrazine monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0128"^^xsd:string) "Catalysis of the reaction: 2 deethylatrazine + O2 = 2 CH3COCH3 + 2 deisopropyldeethylatrazine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "deisopropylatrazine monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R05567"^^xsd:string) "Catalysis of the reaction: 2 deisopropylatrazine + O2 = 2 acetaldehyde + 2 deisopropyldeethylatrazine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:R461-RXN"^^xsd:string) Annotation( "UM-BBD_reactionID:r0127"^^xsd:string) "Catalysis of the reaction: atrazine + O2 + 2 H+ = deethylatrazine + acetaldehyde + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "atrazine N-dealkylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0090"^^xsd:string) "atrazine monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.15.1"^^xsd:string) "camphor methylene hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.1"^^xsd:string) "methylene monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.1"^^xsd:string) "camphor 5-exo-hydroxylase activity"^^xsd:string) AnnotationAssertion( "camphor 5-exo-methylene hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.1"^^xsd:string) "D-camphor-exo-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.1"^^xsd:string) "d-camphor monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.1"^^xsd:string) "2-bornanone 5-exo-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.1"^^xsd:string) "Catalysis of the reaction: (+)-camphor + putidaredoxin + O2 = (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.1"^^xsd:string) "methylene hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "camphor 5-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.1"^^xsd:string) "cytochrome p450-cam activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.1"^^xsd:string) "(+)-camphor,reduced putidaredoxin:oxygen oxidoreductase (5-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.1"^^xsd:string) "camphor hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.1"^^xsd:string) "camphor 5-exohydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.1"^^xsd:string) "bornanone 5-exo-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.15.2"^^xsd:string) "camphor ketolactonase I activity"^^xsd:string) AnnotationAssertion(rdfs:label "camphor 1,2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.2"^^xsd:string) "oxygenase, camphor 1,2-mono"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.2"^^xsd:string) "(+)-camphor,reduced-rubredoxin:oxygen oxidoreductase (1,2-lactonizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.2"^^xsd:string) "ketolactonase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.2"^^xsd:string) "2,5-diketocamphane lactonizing enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.2"^^xsd:string) "Catalysis of the reaction: (1R)-bornane-2,5-dione + reduced rubredoxin + O2 = 5-oxo-1,2-campholide + oxidized rubredoxin + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "alkane 1-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.3"^^xsd:string) "alkane,reduced-rubredoxin:oxygen 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.3"^^xsd:string) "alkane monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.3"^^xsd:string) "omega-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.3"^^xsd:string) "alkane hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.3"^^xsd:string) "lauric acid omega-hydroxylase activity"^^xsd:string) AnnotationAssertion( "fatty acid (omega-1)-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alkane 1-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.3"^^xsd:string) "Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.3"^^xsd:string) "fatty acid omega-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.3"^^xsd:string) "1-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "6-hydroxy pseudo-oxynicotine monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0480"^^xsd:string) "Catalysis of the reaction: 2 6-hydroxypseudooxynicotine + O2 = 2 2,6-dihydroxypseudooxynicotine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.12.18"^^xsd:string) "biphenyl,NADH:oxygen oxidoreductase (2,3-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.18"^^xsd:string) "Catalysis of the reaction: biphenyl + NADH + H+ + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+. This reaction requires Fe2+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.18"^^xsd:string) "biphenyl dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "biphenyl 2,3-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DDT 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0450"^^xsd:string) "Catalysis of the reaction: 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane + O2 + 2 H+ + 2 e- = cis-2,3-dihydrodiol DDT. 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane is also known as DDT."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "naphthalene disulfonate 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0249"^^xsd:string) "Catalysis of the reaction: (1/2)-unsubstituted naphthalenoid-(2/1)-sulfonate + 2 H+ + 2 e- + O2 = 1,2-dihydroxynaphthalene derivative + HSO3(-). Substrates include naphthalene-1,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate), naphthalene-1-sulfonate (forms 1,2-dihydroxynaphthalene), naphthalene-2,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate) and naphthalene-2-sulfonate (forms 1,2-dihydroxynaphthalene)."^^xsd:string) AnnotationAssertion( "naphthalene disulphonate 1,2-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.15"^^xsd:string) "piperonylate-4-O-demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.15"^^xsd:string) "4-methoxybenzoate O-demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.15"^^xsd:string) "4-methoxybenzoate,hydrogen-donor:oxygen oxidoreductase (O-demethylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.15"^^xsd:string) "p-anisic O-demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.15"^^xsd:string) "4-methoxybenzoate 4-monooxygenase (O-demethylating)"^^xsd:string) AnnotationAssertion( "4-methoxybenzoate monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-methoxybenzoate monooxygenase (O-demethylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.15"^^xsd:string) Annotation( "RHEA:18616"^^xsd:string) "Catalysis of the reaction: 4-methoxybenzoate + AH(2) + O(2) = 4-hydroxybenzoate + A + formaldehyde + H(2)O."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.17.99.2"^^xsd:string) "ethylbenzene:(acceptor) oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ethylbenzene hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.99.2"^^xsd:string) "ethylbenzene dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.99.2"^^xsd:string) Annotation( "RHEA:17900"^^xsd:string) "Catalysis of the reaction: A + ethylbenzene + H(2)O = (S)-1-phenylethanol + AH(2)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "p-cymene methyl hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0392"^^xsd:string) "Catalysis of the reaction: p-cymene + NADH + O2 = NAD+ + OH- + p-cumic alcohol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.17.99.1"^^xsd:string) "Catalysis of the reaction: 4-cresol + acceptor + H2O = 4-hydroxybenzaldehyde + reduced acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "4-cresol dehydrogenase (hydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.99.1"^^xsd:string) "4-cresol:acceptor oxidoreductase (methyl-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.99.1"^^xsd:string) "p-cresol-(acceptor) oxidoreductase (hydroxylating) activity"^^xsd:string) AnnotationAssertion( "4-cresol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.99.1"^^xsd:string) "p-cresol methylhydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0600"^^xsd:string) "Catalysis of the reaction: carbonyl sulfide + 2 H+ + 2 e- = hydrogen sulfide + carbon monoxide."^^xsd:string) AnnotationAssertion(rdfs:label "carbonyl sulfide nitrogenase activity"^^xsd:string) AnnotationAssertion( "carbonyl sulphide nitrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0352"^^xsd:string) "Catalysis of the reaction: vinyl chloride + 2 H+ + 2 e- = HCl + ethene."^^xsd:string) AnnotationAssertion(rdfs:label "vinyl chloride reductive dehalogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1,1,1-trichloroethane reductive dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1007"^^xsd:string) "Catalysis of the reaction: 1,1,1-trichloroethane + 2 H+ + 2 e- = 1,1-dichloroethane + HCl."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0719"^^xsd:string) "Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + H+ + 2 e- = Cl- + N-isopropylacetanilide."^^xsd:string) AnnotationAssertion(rdfs:label "2-chloro-N-isopropylacetanilide reductive dehalogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,5-dichlorohydroquinone reductive dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0366"^^xsd:string) "Catalysis of the reaction: organohalide + 2 H+ + 2 e- = R-H + HCl. Reactants include chlorohydroquinone (forms hydroquinone) and 2,5-dichlorohydroquinone (forms chlorohydroquinone)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0440"^^xsd:string) "Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + H+ + 2 e- = Cl- + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene is also known as DDE; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU."^^xsd:string) AnnotationAssertion(rdfs:label "1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity"^^xsd:string) AnnotationAssertion( "1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene dehalogenase activity"^^xsd:string) AnnotationAssertion( "DDE dehalogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0280"^^xsd:string) "Catalysis of the reaction: 2,4-dichlorophenoxyacetic acid + H+ + 2 e- = Cl- + 4-chlorophenoxyacetate."^^xsd:string) AnnotationAssertion(rdfs:label "2,4-dichlorophenoxyacetate dehalogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1,2-dichloroethene reductive dehalogenase activity"^^xsd:string) AnnotationAssertion( "1,2-dichloroethylene reductive dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0272"^^xsd:string) "Catalysis of the reaction: 1,2-dichloroethene + 2 H+ + 2 e- = HCl + vinyl chloride."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.97.1.2"^^xsd:string) "1,2,3,5-tetrahydroxybenzene-pyrogallol hydroxyltransferase (transhydroxylase)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.2"^^xsd:string) "1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.2"^^xsd:string) "transhydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.2"^^xsd:string) "Catalysis of the reaction: 1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene."^^xsd:string) AnnotationAssertion( "pyrogallol hydroxyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyrogallol hydroxytransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.2"^^xsd:string) "1,2,3,5-tetrahydroxybenzene hydroxyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.2"^^xsd:string) "1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxytransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.2"^^xsd:string) "1,2,3,5-tetrahydroxybenzene:pyrogallol transhydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0493"^^xsd:string) "Catalysis of the reaction: 1-phenanthrol + X-CH3 = X + 1-methoxyphenanthrene."^^xsd:string) AnnotationAssertion(rdfs:label "1-phenanthrol methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thiol S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.9"^^xsd:string) "thiol methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.9"^^xsd:string) "TMT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.9"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine + a thioether."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.9"^^xsd:string) "S-adenosyl-L-methionine:thiol S-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.4.1.6"^^xsd:string) "acetone:carbon-dioxide ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "acetone carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.6"^^xsd:string) Annotation( "RHEA:18388"^^xsd:string) "Catalysis of the reaction: acetone + ATP + CO(2) + 2 H(2)O = acetoacetate + AMP + 4 H(+) + 2 phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0243"^^xsd:string) "Catalysis of the reaction: benzoyl acetyl-CoA + CoA = acetyl-CoA + benzoyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "benzoyl acetate-CoA thiolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-hydroxybutyryl-CoA thiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0010"^^xsd:string) "Catalysis of the reaction: 3-hydroxy-5-oxohexanoyl-CoA + CoASH = 3-hydroxybutyryl-CoA + acetyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0197"^^xsd:string) "Catalysis of the reaction: 3-ketopimeloyl-CoA + CoA = glutaryl-CoA + acetyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "3-ketopimelyl-CoA thiolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0567"^^xsd:string) "Catalysis of the reaction: 9-phenanthrol + UDP-glucuronate = 9-phenanthryl-beta-D-glucuronide + UDP."^^xsd:string) AnnotationAssertion(rdfs:label "9-phenanthrol UDP-glucuronosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0525"^^xsd:string) "Catalysis of the reaction: 1-phenanthrol + glucose = 1-phenanthryl-beta-D-glucopyranoside + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "1-phenanthrol glycosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "9-phenanthrol glycosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0511"^^xsd:string) "Catalysis of the reaction: 9-phenanthrol + glucose = 9-phenanthryl-beta-D-glucopyranoside + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0569"^^xsd:string) "Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDP-glucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP."^^xsd:string) AnnotationAssertion(rdfs:label "1,2-dihydroxy-phenanthrene glycosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0449"^^xsd:string) "Catalysis of the reaction: 6-aminohexanoate + alpha-ketoglutarate = glutamate + 6-oxohexanoate."^^xsd:string) AnnotationAssertion(rdfs:label "6-aminohexanoate transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phenol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0155"^^xsd:string) "Catalysis of the reaction: phenol + X-HPO3- = XH + phenylphosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity"^^xsd:string) AnnotationAssertion( "trans-9R,10R-dihydrodiolphenanthrene sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0559"^^xsd:string) "Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-9,10-dihydrodiolsulfate conjugate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "1-phenanthrol sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0565"^^xsd:string) "Catalysis of the reaction: 1-phenanthrol + X-SO3(-) = HX + 1-phenanthrylsulfate."^^xsd:string) AnnotationAssertion(rdfs:label "1-phenanthrol sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3-phenanthrol sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0561"^^xsd:string) "Catalysis of the reaction: 3-phenanthrol + X-SO3(-) = HX + 3-phenanthrylsulfate."^^xsd:string) AnnotationAssertion(rdfs:label "3-phenanthrol sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-phenanthrol sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0562"^^xsd:string) "Catalysis of the reaction: 4-phenanthrol + X-SO3(-) = HX + 4-phenanthrylsulfate."^^xsd:string) AnnotationAssertion( "4-phenanthrol sulphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "trans-3,4-dihydrodiolphenanthrene sulfotransferase activity"^^xsd:string) AnnotationAssertion( "trans-3,4-dihydrodiolphenanthrene sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0558"^^xsd:string) "Catalysis of the reaction: trans-3,4-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-3,4-dihydrodiolsulfate conjugate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "9-phenanthrol sulphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "9-phenanthrol sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0564"^^xsd:string) "Catalysis of the reaction: 9-phenanthrol + X-SO3(-) = HX + 9-phenanthrylsulfate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-phenanthrol sulfotransferase activity"^^xsd:string) AnnotationAssertion( "2-phenanthrol sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0563"^^xsd:string) "Catalysis of the reaction: 2-phenanthrol + X-SO3(-) = HX + 2-phenanthrylsulfate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.3.1"^^xsd:string) "propionyl CoA:acetate CoA transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.1"^^xsd:string) "propionate coenzyme A-transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "propionate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.1"^^xsd:string) "propionyl-CoA transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.1"^^xsd:string) "propionate-CoA:lactoyl-CoA transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.1"^^xsd:string) "acetyl-CoA:propanoate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.1"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + propanoate = acetate + propanoyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.3.12"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + (E)-glutaconate = acetate + glutaconyl-1-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "glutaconate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.12"^^xsd:string) "acetyl-CoA:(E)-glutaconate CoA-transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1-oxa-2-oxocycloheptane lactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0167"^^xsd:string) "Catalysis of the reaction: 1-oxa-2-oxocycloheptane + H2O = 6-hydroxyhexanoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sulpholactone hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfolactone hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0583"^^xsd:string) "Catalysis of the reaction: 4-sulfolactone + OH- = HSO3(-) + maleylacetate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0419"^^xsd:string) "Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl) propionate."^^xsd:string) AnnotationAssertion(rdfs:label "3,4-dihydrocoumarin hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "butyrolactone hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0016"^^xsd:string) "Catalysis of the reaction: butyrolactone + H2O = 4-hydroxybutanoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0206"^^xsd:string) "Catalysis of the reaction: 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA + H2O = 3-hydroxypimeloyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-ketocyclohexane-1-carboxyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0193"^^xsd:string) "Catalysis of the reaction: 2-ketocyclohexane-1-carboxyl-CoA + H2O = pimeloyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "S-formylglutathione hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.12"^^xsd:string) Annotation( "RHEA:14964"^^xsd:string) "Catalysis of the reaction: S-formylglutathione + H(2)O = formate + glutathione + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-hydroxybenzoyl-CoA thioesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.23"^^xsd:string) Annotation( "RHEA:11951"^^xsd:string) "Catalysis of the reaction: 4-hydroxybenzoyl-CoA + H(2)O = 4-hydroxybenzoate + CoA + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.23"^^xsd:string) "4-hydroxybenzoyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion( "4-hydroxybenzoyl-CoA thiolesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.13.1.3"^^xsd:string) "2'-hydroxybiphenyl-2-sulfinate sulfohydrolase activity"^^xsd:string) AnnotationAssertion( "2'-hydroxybiphenyl-2-sulfinate sulfinolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.13.1.3"^^xsd:string) "2-(2'-hydroxyphenyl)benzenesulfinate desulfinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.13.1.3"^^xsd:string) "2-(2-hydroxyphenyl) benzenesulfinate:H2O hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.13.1.3"^^xsd:string) "DszB"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.13.1.3"^^xsd:string) Annotation( "RHEA:12948"^^xsd:string) "Catalysis of the reaction: 2'-hydroxybiphenyl-2-sulfinate + H(2)O = biphenyl-2-ol + sulfite."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.13.1.3"^^xsd:string) "gene dszB-encoded hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.13.1.3"^^xsd:string) "2-(2-hydroxyphenyl) benzenesulfinate sulfohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2'-hydroxybiphenyl-2-sulfinate desulfinase activity"^^xsd:string) AnnotationAssertion( "2-(2-hydroxyphenyl)benzenesulphinate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.13.1.3"^^xsd:string) "2-(2-hydroxyphenyl)benzenesulfinate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.13.1.3"^^xsd:string) "HBPSi desulfinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.13.1.3"^^xsd:string) "HPBS desulfinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.13.1.3"^^xsd:string) "2-(2-hydroxyphenyl)benzenesulfinate desulfinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.13.1.3"^^xsd:string) "dibenzothiophene desulfurization enzyme B"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "alkyl sulphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alkyl sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0602"^^xsd:string) "Catalysis of the reaction: dodecyl sulfate + H2O = sulfate + H+ + 1-dodecanol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0051"^^xsd:string) "Catalysis of the hydrolysis of the ether in chloro- or hydroxyepoxypropane to produce chloropropane diol or glycerol. Acts on R enantiomers."^^xsd:string) AnnotationAssertion(rdfs:label "epoxide hydrolase B activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0560"^^xsd:string) "Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9R,10R-dihydrodiolphenanthrene."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "limonene-1,2-epoxide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.8"^^xsd:string) "Catalysis of the reaction: limonene-1,2-epoxide + H2O = limonene-1,2-diol. Other substrates include alicyclic and 1-methyl-substituted epoxides, such as 1-methylcyclohexene oxide, indene oxide and cyclohexene oxide."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.8"^^xsd:string) "limonene oxide hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0049"^^xsd:string) "Catalysis of the hydrolysis of the ether in chloro-, bromo- or hydroxyepoxypropane to produce a chloro- or bromopropane diol or glycerol."^^xsd:string) AnnotationAssertion(rdfs:label "epoxide hydrolase A activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0535"^^xsd:string) "Catalysis of the reaction: phenanthrene-3,4-oxide + H2O = trans-3,4-dihydrodiolphenanthrene."^^xsd:string) AnnotationAssertion(rdfs:label "phenanthrene-3,4-epoxide hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phenanthrene-1,2-epoxide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0536"^^xsd:string) "Catalysis of the reaction: phenanthrene-1,2-oxide + H2O = trans-1,2-dihydrodiolphenanthrene."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0706"^^xsd:string) "Catalysis of the reaction: iprodione + OH- = 3,5-dichlorophenylcarboximide + N-isopropylcarbamate."^^xsd:string) AnnotationAssertion(rdfs:label "iprodione amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(3,5-dichlorophenylurea)acetate amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0708"^^xsd:string) "Catalysis of the reaction: (3,5-dichlorophenylurea)acetate + OH- = 3,5-dichloroaniline + N-carboxyglycine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.84"^^xsd:string) "Catalysis of the reaction: biuret + H2O = urea + CO2 + NH3."^^xsd:string) AnnotationAssertion(rdfs:label "biuret amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0707"^^xsd:string) "Catalysis of the reaction: 3,5-dichlorophenylcarboximide + OH- = (3,5-dichlorophenylurea)acetate."^^xsd:string) AnnotationAssertion(rdfs:label "3,5-dichlorophenylcarboximide hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0448"^^xsd:string) "Catalysis of the reaction: epsilon-caprolactam + H2O = H+ + 6-aminohexanoate."^^xsd:string) AnnotationAssertion(rdfs:label "epsilon-caprolactam lactamase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyanuric acid amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.15"^^xsd:string) "Catalysis of the reaction: cyanuric acid + H2O = biuret + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ammelide aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:1991731"^^xsd:string) "Catalysis of the reaction: ammelide + H2O = cyanuric acid + NH3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1414"^^xsd:string) "Catalysis of the reaction: 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + OH- = 2,4-dihydroxy-6-amino-1,3,5-triazine + Cl-."^^xsd:string) AnnotationAssertion(rdfs:label "2-chloro-4-hydroxy-6-amino-1,3,5-triazine aminohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ammeline aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:1991731"^^xsd:string) "Catalysis of the reaction: ammeline + H2O = ammelide + NH3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0121"^^xsd:string) "Catalysis of the reaction: deisopropylhydroxyatrazine + H2O = NH3 + 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine."^^xsd:string) AnnotationAssertion(rdfs:label "deisopropylhydroxyatrazine aminohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0122"^^xsd:string) "Catalysis of the reaction: 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine + H2O = CH3CH2NH2 + cyanuric acid."^^xsd:string) AnnotationAssertion(rdfs:label "2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine aminohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methenyltetrahydromethanopterin cyclohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.27"^^xsd:string) "methenyl-H(4)MPT cyclohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.27"^^xsd:string) "N5,N10-methenyltetrahydromethanopterin cyclohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.27"^^xsd:string) "5,10-methenyltetrahydromethanopterin 10-hydrolase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.27"^^xsd:string) "5,10-methenyltetrahydromethanopterin cyclohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.27"^^xsd:string) "methenyl-H4MPT cyclohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.27"^^xsd:string) Annotation( "RHEA:19056"^^xsd:string) "Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2)O = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.5.8"^^xsd:string) "thiocyanate aminohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiocyanate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.5.8"^^xsd:string) Annotation( "RHEA:21467"^^xsd:string) "Catalysis of the reaction: H(2)O + 2 H(+) + thiocyanate = carbonyl sulfide + NH(4)(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3,5-dibromo-4-hydroxybenzonitrile aminohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "bromoxynil nitrilase activity"^^xsd:string) AnnotationAssertion( "bromoxynil-specific nitrilase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.5.6"^^xsd:string) Annotation( "RHEA:22103"^^xsd:string) "Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H(2)O = 3,5-dibromo-4-hydroxybenzoate + NH(4)(+). Involved in the bacterial degradation of the herbicide bromoxynil."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.5.7"^^xsd:string) "aliphatic nitrile aminohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aliphatic nitrilase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.5.7"^^xsd:string) "Catalysis of the reaction: R-CN + H2O = R-COOH + NH3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "hydroxyatrazine ethylaminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.3"^^xsd:string) "AtzB"^^xsd:string) AnnotationAssertion(rdfs:label "hydroxydechloroatrazine ethylaminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.3"^^xsd:string) "hydroxyatrazine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.3"^^xsd:string) "4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine ethylaminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.3"^^xsd:string) "Catalysis of the reaction: 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + H2O = N-isopropylammelide + ethylamine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.99.4"^^xsd:string) "AtzC"^^xsd:string) AnnotationAssertion(rdfs:label "N-isopropylammelide isopropylaminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.4"^^xsd:string) "Catalysis of the reaction: N-isopropylammelide + H2O = cyanuric acid + isopropylamine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0263"^^xsd:string) "Catalysis of the reaction: cis,cis-2-hydroxy-6-oxohept-2,4-dienoate + OH- = cis-2-hydroxypenta-2,4-dienoate + acetate."^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxy-6-oxohepta-2,4-dienoate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0008"^^xsd:string) "Catalysis of the reaction: dihydrophloroglucinol + OH- = 3-hydroxy-5-oxohexanoate."^^xsd:string) AnnotationAssertion(rdfs:label "dihydrophloroglucinol hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0399"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + isobutyrate."^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0458"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate + H2O = 2-aminobenzoate + cis-2-hydroxypenta-2,4-dienoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0311"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-6-oxoocta-2,4-dienoate + H2O = H+ + propanoate + cis-2-hydroxypenta-2,4-dienoate."^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxy-6-oxoocta-2,4-dienoate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0444"^^xsd:string) "Catalysis of the reaction: 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2Z,4Z,7-trienoate + H2O = 2-(4'-chlorophenyl)-3,3-dichloropropenoate + cis-2-Hydroxy-3-chloropenta-2,4-dienone + H+."^^xsd:string) AnnotationAssertion(rdfs:label "6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.14"^^xsd:string) Annotation( ) "(2E,4Z)-2-hydroxy-6-oxona-2,4-dienedioate succinylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:24792"^^xsd:string) "Catalysis of the reaction: (2E,4Z)-2-hydroxy-6-oxonona-2,4-dienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + H+ + succinate."^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0438"^^xsd:string) "2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:R306-RXN"^^xsd:string) Annotation( "UM-BBD_reactionID:r0094"^^xsd:string) "Catalysis of the reaction: 2,4,6-trioxoheptanoate + H2O = acetylpyruvate + acetate."^^xsd:string) AnnotationAssertion(rdfs:label "trioxoheptanoate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acetylpyruvate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.6"^^xsd:string) Annotation( "RHEA:16100"^^xsd:string) "Catalysis of the reaction: acetylpyruvate + H(2)O = acetate + H(+) + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.6"^^xsd:string) "2,4-dioxopentanoate acetylhydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.8"^^xsd:string) "Catalysis of the reaction: 2,6-dioxo-6-phenylhexa-3-enoate + H2O = benzoate + 2-oxopent-4-enoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.8"^^xsd:string) "HOHPDA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.8"^^xsd:string) "2,6-dioxo-6-phenylhexa-3-enoate benzoylhydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.7.1.9"^^xsd:string) "2-hydroxymuconate-semialdehyde formylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.9"^^xsd:string) "Catalysis of the reaction: 2-hydroxymuconate semialdehyde + H2O = formate + 2-oxopent-4-enoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.9"^^xsd:string) "2-hydroxymuconic semialdehyde hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxymuconate-semialdehyde hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.9"^^xsd:string) "HOD hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.9"^^xsd:string) "HMSH"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "trans-chloroacrylic acid dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0689"^^xsd:string) "Catalysis of the reaction: trans-3-chloroacrylic acid + H2O = H+ + malonate semialdehyde."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1,3,4,6-tetrachloro-1,4-cyclohexadiene halidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10464214"^^xsd:string) "Catalysis of the reaction: alkyl halide + H2O = alcohol + HCl. Substrates are 1,3(R),4,6(R)-tetrachloro-1,4-cyclohexadiene (forms 2,4,5-trichloro-2,5-cyclohexadiene-1-ol) and 2,4,5-trichloro-2,5-cyclohexadiene-1-ol (forms 2,5-dichloro-2,5-cyclohexadiene-1,4-diol)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0382"^^xsd:string) "Catalysis of the reaction: trichloroacetate + 2 H2O = 3 H+ + 3 Cl- + oxalate."^^xsd:string) AnnotationAssertion(rdfs:label "DL-2 haloacid dehalogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0383"^^xsd:string) "Catalysis of the reaction: dichloroacetate + H2O = 2 HCl + glyoxylate."^^xsd:string) AnnotationAssertion(rdfs:label "dichloroacetate halidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_ruleID:bt0330"^^xsd:string) "Catalysis of the reaction: 1-halo or 1-pseudohalo-S-triazine = 1-hydroxy-S-triazine."^^xsd:string) AnnotationAssertion(rdfs:label "S-triazine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0688"^^xsd:string) "Catalysis of the reaction: cis-3-chloroacrylic acid + H2O = H+ + HCl + malonate semialdehyde."^^xsd:string) AnnotationAssertion(rdfs:label "cis-chloroacrylic acid dehalogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "deisopropyldeethylatrazine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:0129"^^xsd:string) "Catalysis of the reaction: deisopropyldeethylatrazine + H2O = 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + NH3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(S)-2-haloacid dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.2"^^xsd:string) "2-haloalkanoid acid halidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.2"^^xsd:string) "L-DEX activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.2"^^xsd:string) "(S)-2-haloacid halidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.2"^^xsd:string) "2-haloalkanoic acid dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.2"^^xsd:string) "DL-2-haloacid dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.2"^^xsd:string) "halocarboxylic acid halidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.2"^^xsd:string) "Catalysis of the reaction: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.2"^^xsd:string) "2-halocarboxylic acid dehalogenase II activity"^^xsd:string) AnnotationAssertion( "2-haloacid dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.2"^^xsd:string) "L-2-haloacid dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.2"^^xsd:string) "2-haloacid halidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "haloacetate dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.3"^^xsd:string) "haloacetate halidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.3"^^xsd:string) "monohaloacetate dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.3"^^xsd:string) "Catalysis of the reaction: haloacetate + H2O = glycolate + halide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.8.1.5"^^xsd:string) "1-chlorohexane halidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.5"^^xsd:string) "1-haloalkane dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.5"^^xsd:string) "Catalysis of the reaction: 1-haloalkane + H2O = a primary alcohol + halide."^^xsd:string) AnnotationAssertion(rdfs:label "haloalkane dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.5"^^xsd:string) "1-haloalkane halidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.8.1.7"^^xsd:string) "Catalysis of the reaction: 4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl CoA + chloride."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.7"^^xsd:string) "4-chlorobenzoyl CoA chlorohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-chlorobenzoyl-CoA dehalogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "atrazine chlorohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.8"^^xsd:string) "AtzA"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.8"^^xsd:string) Annotation( "RHEA:11315"^^xsd:string) "Catalysis of the reaction: atrazine + H(2)O = 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + chloride + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.10.1.2"^^xsd:string) "cyclamate sulfamidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyclamate sulfohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.10.1.2"^^xsd:string) "cyclohexylsulfamate sulfamidase activity"^^xsd:string) AnnotationAssertion( "cyclamate sulfamatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.10.1.2"^^xsd:string) "cyclohexylsulfamate sulfohydrolase activity"^^xsd:string) AnnotationAssertion( "cyclamate sulphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.10.1.2"^^xsd:string) Annotation( "RHEA:18484"^^xsd:string) "Catalysis of the reaction: cyclohexylsulfamate + H(2)O = cyclohexylamine + sulfate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0398"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate = CO2 + 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate."^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bis(4-chlorophenyl)acetate decarboxylase activity"^^xsd:string) AnnotationAssertion( "DDA decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0520"^^xsd:string) "Catalysis of the reaction: bis(4-chlorophenyl)acetate + H+ = CO2 + bis(4-chlorophenyl)methane. Bis(4-chlorophenyl)acetate is also known as DDA; bis(4-chlorophenyl)methane is also known as DDM."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3,5-dibromo-4-hydroxybenzoate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0546"^^xsd:string) "Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzoate + H+ = CO2 + 2,6-dibromophenol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxyisobutyrate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0617"^^xsd:string) "Catalysis of the reaction: 2-hydroxyisobutyrate + H+ = CO2 + 2-propanol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxy-2-methyl-1,3-dicarbonate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0621"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-2-methyl-1,3-dicarbonate + H+ = CO2 + L-lactate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.55"^^xsd:string) "Catalysis of the reaction: 4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.55"^^xsd:string) "4,5-dihydroxyphthalate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.55"^^xsd:string) "4,5-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "4,5-dihydroxyphthalate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.59"^^xsd:string) "gallate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "gallate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.59"^^xsd:string) Annotation( "RHEA:12752"^^xsd:string) "Catalysis of the reaction: gallate + H(+) = CO(2) + pyrogallol."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.59"^^xsd:string) "gallate carboxy-lyase (pyrogallol-forming)"^^xsd:string) AnnotationAssertion( "gallic acid decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-hydroxybenzoate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.61"^^xsd:string) Annotation( "RHEA:10879"^^xsd:string) "Catalysis of the reaction: 4-hydroxybenzoate + H(+) = CO(2) + phenol."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.61"^^xsd:string) "4-hydroxybenzoate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.61"^^xsd:string) "4-hydroxybenzoate carboxy-lyase (phenol-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.61"^^xsd:string) "p-hydroxybenzoate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase activity"^^xsd:string) AnnotationAssertion( "HpaG-2"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.68"^^xsd:string) "Catalysis of the reaction: 5-oxopent-3-ene-1,2,5-tricarboxylate = 2-oxohept-3-enedioate + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.68"^^xsd:string) "5-carboxymethyl-2-oxo-hex-3-ene-1,6-dioate decarboxylase activity"^^xsd:string) AnnotationAssertion( "OPET decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.68"^^xsd:string) "5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.68"^^xsd:string) "5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase (2-oxohept-3-enedioate-forming)"^^xsd:string) AnnotationAssertion( "HpaG2"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutaconyl-CoA decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.70"^^xsd:string) Annotation( "RHEA:23975"^^xsd:string) "Catalysis of the reaction: trans-glutaconyl-CoA + H(+) = but-2-enoyl-CoA + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.70"^^xsd:string) "4-carboxybut-2-enoyl-CoA carboxy-lyase (but-2-enoyl-CoA-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.70"^^xsd:string) "glutaconyl coenzyme A decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.70"^^xsd:string) "4-carboxybut-2-enoyl-CoA carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.70"^^xsd:string) "pent-2-enoyl-CoA carboxy-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,4-dihydroxyhept-2-ene-1,7-dioate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0370"^^xsd:string) "Catalysis of the reaction: 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate = pyruvate + succinic semialdehyde."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.34"^^xsd:string) "(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase (pyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.34"^^xsd:string) "2'-carboxybenzalpyruvate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.34"^^xsd:string) "(3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase activity"^^xsd:string) AnnotationAssertion( "trans-2'-carboxybenzalpyruvate hydratase-aldolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.34"^^xsd:string) "(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.34"^^xsd:string) "Catalysis of the reaction: (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate = 2-carboxybenzaldehyde + pyruvate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "benzylsuccinate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.11"^^xsd:string) "benzylsuccinate fumarate-lyase (toluene-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.11"^^xsd:string) Annotation( "RHEA:10419"^^xsd:string) "Catalysis of the reaction: fumarate + toluene = 2-benzylsuccinate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.11"^^xsd:string) "benzylsuccinate fumarate-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "6-hydroxycyclohex-1-ene-1-carboxyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0204"^^xsd:string) "Catalysis of the reaction: 6-hydroxycyclohex-1-ene-1-carboxyl-CoA + H2O = 2,6-dihydroxycyclohexane-1-carboxyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0484"^^xsd:string) "Catalysis of the reaction: trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate + H2O = pyruvate + 1-hydroxy-2-naphthaldehyde."^^xsd:string) AnnotationAssertion(rdfs:label "trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate hydratase-aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0331"^^xsd:string) "Catalysis of the reaction: E-phenylitaconyl-CoA + H2O = (hydroxymethylphenyl)succinyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "E-phenylitaconyl-CoA hydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0164"^^xsd:string) "Catalysis of the reaction: trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate + H2O = pyruvate + 3-hydroxy-2-formylbenzothiophene."^^xsd:string) AnnotationAssertion(rdfs:label "trans-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate hydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:R266-RXN"^^xsd:string) Annotation( "UM-BBD_reactionID:r0191"^^xsd:string) "Catalysis of the reaction: cyclohex-1-ene-1-carboxyl-CoA + H2O = 2-hydroxycyclohexane-1-carboxyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "cyclohex-1-ene-1-carboxyl-CoA hydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_ruleID:bt0291"^^xsd:string) "Catalysis of the reaction: alkene-CoA + H2O = alcohol-CoA. Substrates are crotonoyl-CoA (producing 3-hydroxyacyl-CoA) and 2,3-didehydro-pimeloyl-CoA (producing 3-hydroxypimeloyl-CoA)."^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxyacyl-CoA dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "trans-o-hydroxybenzylidenepyruvate hydratase-aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0257"^^xsd:string) "Catalysis of the reaction: 2-oxo-3-enoate-4-benzenoid + H2O = pyruvate + benzaldehyde derivative. Substrates are (3E)-4-(5-amino-2-hydroxy-phenyl)-2-oxo-but-3-ene-1-oic-acid (forms 5-aminosalicylaldehyde) and trans-o-hydroxybenzylidenepyruvate (forms salicylaldehyde)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phenylacetaldoxime dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.7"^^xsd:string) "(Z)-phenylacetaldehyde-oxime hydro-lyase (phenylacetonitrile-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.7"^^xsd:string) "OxdB"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.7"^^xsd:string) Annotation( "RHEA:20072"^^xsd:string) "Catalysis of the reaction: (trans)-phenylacetaldoxime = H(2)O + phenylacetonitrile."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.7"^^xsd:string) "PAOx dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.7"^^xsd:string) "arylacetaldoxime dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.7"^^xsd:string) "(Z)-phenylacetaldehyde-oxime hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon hydratase-aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-645"^^xsd:string) Annotation( "UM-BBD_reactionID:r0051"^^xsd:string) "Catalysis of the reaction: 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon + H2O = 2-oxobut-3-enanoate + 2,5,6-trihydroxy-3-methylpyridine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0618"^^xsd:string) "Catalysis of the reaction: 2-hydroxyisobutyrate = H2O + methacrylate."^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxyisobutyrate dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2-oxo-hepta-3-ene-1,7-dioic acid hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0369"^^xsd:string) "Catalysis of the reaction: cis-2-oxohept-3-ene-1,7-dioate + H2O = 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate."^^xsd:string) AnnotationAssertion( "HpaH"^^xsd:string) AnnotationAssertion( "2-oxo-hepta-3-ene-1,7-dioate hydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-oxo-hept-3-ene-1,7-dioate hydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.112"^^xsd:string) "AH"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.112"^^xsd:string) "acetaldehyde hydro-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetylene hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.112"^^xsd:string) "AHy"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.112"^^xsd:string) Annotation( "RHEA:17888"^^xsd:string) "Catalysis of the reaction: acetaldehyde = acetylene + H(2)O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.54"^^xsd:string) "lactoyl coenzyme A dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.54"^^xsd:string) "lactyl-coenzyme A dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.54"^^xsd:string) "lactyl CoA dehydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lactoyl-CoA dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.54"^^xsd:string) "lactoyl-CoA hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.54"^^xsd:string) "acrylyl coenzyme A hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.54"^^xsd:string) "Catalysis of the reaction: lactoyl-CoA = acryloyl-CoA + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.54"^^xsd:string) "lactoyl-CoA hydro-lyase (acryloyl-CoA-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyanamide hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.69"^^xsd:string) Annotation( "RHEA:23059"^^xsd:string) "Catalysis of the reaction: urea = cyanamide + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.69"^^xsd:string) "urea hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.69"^^xsd:string) "urea hydro-lyase (cyanamide-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.84"^^xsd:string) "H-NHase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.84"^^xsd:string) "Catalysis of the reaction: an aliphatic amide = a nitrile + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.84"^^xsd:string) "nitrile hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.84"^^xsd:string) "NHase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.84"^^xsd:string) "L-NHase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nitrile hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.84"^^xsd:string) "aliphatic-amide hydro-lyase (nitrile-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.84"^^xsd:string) "3-cyanopyridine hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.84"^^xsd:string) "aliphatic nitrile hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.84"^^xsd:string) "acrylonitrile hydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.100"^^xsd:string) "cyclohexa-1,5-dienecarbonyl-CoA hydro-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyclohexa-1,5-dienecarbonyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.100"^^xsd:string) "dienoyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion( "cyclohex-1,5-diene-1-carbonyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.100"^^xsd:string) "cyclohexa-1,5-diene-1-carboxyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.100"^^xsd:string) "6-hydroxycyclohex-1-enecarbonyl-CoA (cyclohexa-1,5-dienecarbonyl-CoA-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.100"^^xsd:string) Annotation( "RHEA:21859"^^xsd:string) "Catalysis of the reaction: cyclohexa-1,5-diene-1-carbonyl-CoA + H(2)O = 6-hydroxycyclohex-1-enecarbonyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.100"^^xsd:string) "cyclohexa-1,5-diene-1-carbonyl-CoA hydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.4.1"^^xsd:string) "HAB mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.4.1"^^xsd:string) "hydroxylaminobenzene mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.4.1"^^xsd:string) "hydroxylaminobenzene hydroxymutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.4.1"^^xsd:string) "(hydroxyamino)benzene hydroxymutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.4.1"^^xsd:string) Annotation( "UM-BBD_reactionID:r0304"^^xsd:string) "Catalysis of the reaction: (hydroxyamino)benzene = 2-aminophenol."^^xsd:string) AnnotationAssertion(rdfs:label "(hydroxyamino)benzene mutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "triethanolamine lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0421"^^xsd:string) "Catalysis of the reaction: triethanolamine = diethanolamine + acetaldehyde."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.11"^^xsd:string) "L-methionine methanethiol-lyase (deaminating; 2-oxobutanoate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.11"^^xsd:string) "L-methionine methanethiol-lyase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.11"^^xsd:string) "Catalysis of the reaction: L-methionine = methanethiol + NH3 + 2-oxobutanoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.11"^^xsd:string) "methioninase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.11"^^xsd:string) "L-methioninase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.11"^^xsd:string) "methionine dethiomethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.11"^^xsd:string) "L-methionine gamma-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.11"^^xsd:string) "methionine lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methionine gamma-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0515"^^xsd:string) "Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethane = HCl + unsym-bis(4-chlorophenyl)ethene. 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS; unsym-bis(4-chlorophenyl)ethene is also known as DDNU."^^xsd:string) AnnotationAssertion(rdfs:label "1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity"^^xsd:string) AnnotationAssertion( "DDMS dehydrochlorinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "halohydrin hydrogen-halide-lyase A activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0048"^^xsd:string) "Catalysis of the elimination of HCl from a chloro- or bromopropanol, yielding an epoxypropane."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0513"^^xsd:string) "Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane = HCl + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane is also known as DDD; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU."^^xsd:string) AnnotationAssertion(rdfs:label "1,1-dichloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity"^^xsd:string) AnnotationAssertion( "DDD dehydrochlorinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "gamma-hexachlorocyclohexane dehydrochlorinase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0359"^^xsd:string) "Catalysis of the reaction: gamma-hexachlorocyclohexane + HCl = 1,3(R),4(S),5(S),6(R)-pentachlorocyclohexene."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5-chloro-1,2,4-trihydroxybenzene dechlorinase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0666"^^xsd:string) "Catalysis of the reaction: 5-chloro-1,2,4-trihydroxybenzene = Cl- + H+ + 2-hydroxy-1,4-benzoquinone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0050"^^xsd:string) "Catalysis of the elimination of HCl from a chloropropanol, yielding an epoxypropane."^^xsd:string) AnnotationAssertion(rdfs:label "halohydrin hydrogen-halide-lyase B activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.5.1.1"^^xsd:string) "DDT-as"^^xsd:string) AnnotationAssertion( "DDT dehydrochlorinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.5.1.1"^^xsd:string) "DDTase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.5.1.1"^^xsd:string) "1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase [1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene-forming]"^^xsd:string) AnnotationAssertion(rdfs:label "DDT-dehydrochlorinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.5.1.1"^^xsd:string) Annotation( "RHEA:19220"^^xsd:string) "Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.5.1.1"^^xsd:string) "DDT-ase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.5.1.1"^^xsd:string) "1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.5.1.3"^^xsd:string) "dichloromethane chloride-lyase (adding H2O; chloride-hydrolysing; formaldehyde-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.5.1.3"^^xsd:string) Annotation( "RHEA:15400"^^xsd:string) "Catalysis of the reaction: dichloromethane + H(2)O = 2 chloride + formaldehyde + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.5.1.3"^^xsd:string) "dichloromethane chloride-lyase (chloride-hydrolysing)"^^xsd:string) AnnotationAssertion(rdfs:label "dichloromethane dehalogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0057"^^xsd:string) "Catalysis of the reaction: alkylphosphonic acid = R-CH3 + phosphate. Substrates include aminomethylphosphonic acid (AMPA) (forms methylamine), dimethylphosphinic acid (forms methylphosphonic acid), glyphosate (forms sarcosine) and methylphosphonic acid (forms phosphate)."^^xsd:string) AnnotationAssertion(rdfs:label "carbon phosphorus lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.99.1.2"^^xsd:string) "alkylmercury mercuric-lyase (alkane-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.2"^^xsd:string) "organomercury lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.2"^^xsd:string) "Catalysis of the reaction: R-Hg+ + H+ = R-H + Hg2+."^^xsd:string) AnnotationAssertion(rdfs:label "alkylmercury lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.2"^^xsd:string) "organomercurial lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.2"^^xsd:string) "alkylmercury mercuric-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxy-2H-benzo[h]chromene-2-carboxylate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0502"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate = cis -4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mandelate racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.2.2"^^xsd:string) "Catalysis of the reaction: (S)-mandelate = (R)-mandelate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0163"^^xsd:string) "Catalysis of the reaction: cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate = trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate."^^xsd:string) AnnotationAssertion(rdfs:label "cis-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-carboxymuconate cycloisomerase type II activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0582"^^xsd:string) "Catalysis of the reaction: 3-sulfomuconate = 4-sulfolactone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxytetrahydrofuran isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0019"^^xsd:string) "Catalysis of the reaction: 2-hydroxytetrahydrofuran = 4-hydroxybutyraldehyde."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxychromene-2-carboxylate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:27404"^^xsd:string) "Catalysis of the reaction: 2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate. (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate is also known as trans-o-hydroxybenzylidenepyruvate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.99.7"^^xsd:string) "styrene-oxide isomerase (epoxide-cleaving)"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.7"^^xsd:string) Annotation( "RHEA:21607"^^xsd:string) "Catalysis of the reaction: styrene oxide = phenylacetaldehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.7"^^xsd:string) "SOI activity"^^xsd:string) AnnotationAssertion( "styrene oxide isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "styrene-oxide isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-pinene lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0712"^^xsd:string) "Catalysis of the reaction: alpha-pinene = limonene."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pinocarveol isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0715"^^xsd:string) "Catalysis of the reaction: pinocarveol = carveol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "muconate cycloisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.1"^^xsd:string) "cis,cis-muconate-lactonizing enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.1"^^xsd:string) "Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = cis,cis-hexadienedioate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.1"^^xsd:string) "4-carboxymethyl-4-hydroxyisocrotonolactone lyase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.1"^^xsd:string) "cis,cis-muconate lactonizing enzyme I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.1"^^xsd:string) "muconate cycloisomerase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.1"^^xsd:string) "muconate lactonizing enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.1"^^xsd:string) "cis,cis-muconate cycloisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.1"^^xsd:string) "2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.5.1.7"^^xsd:string) "Catalysis of the reaction: 2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis-muconate."^^xsd:string) AnnotationAssertion(rdfs:label "chloromuconate cycloisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.7"^^xsd:string) "muconate cycloisomerase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.7"^^xsd:string) "2-chloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "alpha-pinene oxide lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.10"^^xsd:string) Annotation( "RHEA:16696"^^xsd:string) "Catalysis of the reaction: alpha-pinene oxide = (Z)-2-methyl-5-isopropylhexa-2,5-dienal."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.10"^^xsd:string) "alpha-pinene-oxide lyase (decyclizing)"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-pinene-oxide decyclase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dichloromuconate cycloisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.11"^^xsd:string) "Catalysis of the reaction: 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate = 2,4-dichloro-cis,cis-muconate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.11"^^xsd:string) "2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0737"^^xsd:string) "Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0429"^^xsd:string) "Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetate + ATP + CoA = AMP + diphosphate + 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "benzoyl acetate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0242"^^xsd:string) "Catalysis of the reaction: 3-oxo-3-phenylpropionate + CoA + ATP = AMP + diphosphate + benzoyl acetyl-CoA."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,4-dichlorobenzoate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0137"^^xsd:string) "Catalysis of the reaction: 2,4-dichlorobenzoate + ATP + CoASH = AMP + diphosphate + 2,4-dichlorobenzoyl-CoA."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "benzoate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.25"^^xsd:string) "benzoyl CoA synthetase (AMP forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.25"^^xsd:string) "benzoate-coenzyme A ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.25"^^xsd:string) "benzoyl-coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.25"^^xsd:string) "benzoate:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.25"^^xsd:string) Annotation( "RHEA:10135"^^xsd:string) "Catalysis of the reaction: ATP + benzoate + CoA = AMP + benzoyl-CoA + diphosphate + H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.27"^^xsd:string) "4-hydroxybenzoate-coenzyme A ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.27"^^xsd:string) "Catalysis of the reaction: ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxybenzoate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.27"^^xsd:string) "4-hydroxybenzoyl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.27"^^xsd:string) "4-hydroxybenzoyl-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.27"^^xsd:string) "4-hydroxybenzoate-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.27"^^xsd:string) "4-hydroxybenzoate:CoA ligase (AMP-forming)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "anthranilate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.32"^^xsd:string) "2-aminobenzoate coenzyme A ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.32"^^xsd:string) "2-aminobenzoate-coenzyme A ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.32"^^xsd:string) "2-aminobenzoate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.32"^^xsd:string) "Catalysis of the reaction: ATP + anthranilate + CoA = AMP + diphosphate + anthranilyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.32"^^xsd:string) "anthraniloyl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.32"^^xsd:string) "anthranilate:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion( "anthranilate--CoA ligase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-chlorobenzoate-CoA ligase activity"^^xsd:string) AnnotationAssertion( "4-chlorobenzoate:CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.33"^^xsd:string) "Catalysis of the reaction: 4-chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate. This reaction requires magnesium and is part of the bacterial 2,4-dichlorobenzoate degradation pathway."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phenylphosphate carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0157"^^xsd:string) "Catalysis of the reaction: phenylphosphate + CO2 + H2O = H+ + phosphate + 4-hydroxybenzoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0496"^^xsd:string) "Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9(S),10(S)-dihydrodiolphenanthrene."^^xsd:string) AnnotationAssertion(rdfs:label "phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "guanyl nucleotide binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with guanyl nucleotides, any compound consisting of guanosine esterified with (ortho)phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with GMP, guanosine monophosphate."^^xsd:string) AnnotationAssertion(rdfs:label "GMP binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "GDP binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "S-adenosyl-methionine:farnesoic acid O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12135499"^^xsd:string) "Catalysis of the reaction: farnesoic acid + S-adenosyl-methionine = methyl farnesoate + S-adenosyl-L-homocysteine."^^xsd:string) AnnotationAssertion(rdfs:label "farnesoic acid O-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "pyrimidine nucleotide binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:11554296"^^xsd:string) "Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site."^^xsd:string) AnnotationAssertion( "DNA glycosylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "DNA N-glycosylase activity"^^xsd:string) AnnotationAssertion( "endonuclease VIII activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a palmitoyl group to a nitrogen atom on the acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "N-palmitoyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a myristoyl (CH3-[CH2]12-CO-) group to an acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "myristoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aryl-aldehyde dehydrogenase (NAD) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.29"^^xsd:string) "Catalysis of the reaction: an aromatic aldehyde + NAD+ + H2O = an aromatic acid + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.29"^^xsd:string) "aryl-aldehyde:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phenanthrol sulfotransferase activity"^^xsd:string) AnnotationAssertion( "phenanthrol sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.-"^^xsd:string) "Catalysis of the reaction: phenanthrol + X-SO3(-) = HX + phenanthrylsulfate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phenanthrol glycosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: phenanthrol + glucose = phenanthryl-beta-D-glucopyranoside + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of a monooxygenase reaction in which oxygen is incorporated into limonene."^^xsd:string) AnnotationAssertion(rdfs:label "limonene monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "MetaCyc:CATECHOL-12-DIOXYGENASE-RXN"^^xsd:string) Annotation( "MetaCyc:CATECHOL-23-DIOXYGENASE-RXN"^^xsd:string) "Catalysis of the reaction: catechol + O2 = a muconate."^^xsd:string) AnnotationAssertion(rdfs:label "catechol dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.28"^^xsd:string) Annotation( "EC:1.2.1.7"^^xsd:string) "Catalysis of the reaction: benzaldehyde + NAD(P)+ + H2O = benzoate + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(rdfs:label "benzaldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroxy-nicotine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "http://umbbd.ahc.umn.edu/"^^xsd:string) "Catalysis of the reaction: 6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + hydrogen peroxide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "UM-BBD_reactionID:r0415"^^xsd:string) Annotation( "UM-BBD_reactionID:r0422"^^xsd:string) "Catalysis of the reaction: a dihydroxyfluorene + O2 = the corresponding 2-hydroxy-4-(oxo-1,3-dihydro-2H-inden-ylidene) but-2-enoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "dihydroxyfluorene dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phenanthrene-epoxide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "UM-BBD_reactionID:r0535"^^xsd:string) Annotation( "UM-BBD_reactionID:r0536"^^xsd:string) "Catalysis of the reaction: a phenanthrene dioxide + H2O = a dihydrodiolphenanthrene."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "UM-BBD_reactionID:r0496"^^xsd:string) Annotation( "UM-BBD_reactionID:r0560"^^xsd:string) "Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9,10-dihydrodiolphenanthrene."^^xsd:string) AnnotationAssertion(rdfs:label "phenanthrene-9,10-epoxide hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydrolase activity, acting on acid halide bonds, in C-halide compounds"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the hydrolysis of any acid halide bond in substances containing halogen atoms in organic linkage."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.15.7"^^xsd:string) "choline,reduced-ferredoxin:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.7"^^xsd:string) "Catalysis of the reaction: choline + 2 reduced ferredoxin + O2 + 2 H+ = betaine aldehyde hydrate + 2 oxidized ferredoxin + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "choline monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.157"^^xsd:string) "acetyl-CoA:D-glucosamine-1-phosphate N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucosamine-1-phosphate N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.157"^^xsd:string) "acetyl-CoA:alpha-D-glucosamine-1-phosphate N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.157"^^xsd:string) Annotation( "RHEA:13728"^^xsd:string) "Catalysis of the reaction: alpha-D-glucosamine 1-phosphate + acetyl-CoA = N-acetyl-alpha-D-glucosamine 1-phosphate + CoA + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.29"^^xsd:string) "Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.29"^^xsd:string) "DOHH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.29"^^xsd:string) "deoxyhypusine,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "deoxyhypusine monooxygenase activity"^^xsd:string) AnnotationAssertion( "deoxyhypusine hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.29"^^xsd:string) "deoxyhypusine dioxygenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.145"^^xsd:string) "multifunctional deoxynucleoside kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "deoxynucleoside kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.145"^^xsd:string) "multisubstrate deoxyribonucleoside kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.145"^^xsd:string) "ATP:deoxynucleoside 5'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.145"^^xsd:string) "D. melanogaster deoxynucleoside kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.145"^^xsd:string) "multispecific deoxynucleoside kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.145"^^xsd:string) "Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.145"^^xsd:string) "Dm-dNK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.145"^^xsd:string) "Ms-dNK activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.145"^^xsd:string) "ms-dNK"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thioglucosidase activity"^^xsd:string) AnnotationAssertion( "myrosinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.147"^^xsd:string) "Catalysis of the reaction: a thioglucoside + H2O = a thiol + a sugar."^^xsd:string) AnnotationAssertion( "thioglucoside glucohydrolase activity"^^xsd:string) AnnotationAssertion( "sinigrinase activity"^^xsd:string) AnnotationAssertion( "sinigrase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.99.12"^^xsd:string) "6-N-dimethylallyladenine:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.12"^^xsd:string) "Catalysis of the reaction: N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced electron acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.12"^^xsd:string) "N6-dimethylallyladenine:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.12"^^xsd:string) "N6-dimethylallyladenine:(acceptor) oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cytokinin dehydrogenase activity"^^xsd:string) AnnotationAssertion( "cytokinin oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.64"^^xsd:string) "myo-inositol 1-kinase activity"^^xsd:string) AnnotationAssertion( "myo-inositol 3-kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol 3-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.64"^^xsd:string) "inositol-1-kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.64"^^xsd:string) "myoinositol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.64"^^xsd:string) "ATP:myo-inositol 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.64"^^xsd:string) "inositol 1-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.64"^^xsd:string) "Catalysis of the reaction: ATP + myo-inositol = ADP + 1D-myo-inositol 3-phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2-dehydropantoyl-lactone reductase (B-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.214"^^xsd:string) "(R)-pantolactone:NADP+ oxidoreductase (B-specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.214"^^xsd:string) "2-oxopantoyl lactone reductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.214"^^xsd:string) "2-ketopantoyl lactone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.214"^^xsd:string) "Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.214"^^xsd:string) "ketopantoyl lactone reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-dehydropantolactone reductase (B-specific) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.3.11"^^xsd:string) Annotation( "RHEA:19188"^^xsd:string) "Catalysis of the reaction: glyoxylate + H(2)O + propanoyl-CoA = 2-hydroxyglutarate + CoA + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.11"^^xsd:string) "propanoyl-CoA:glyoxylate C-propanoyltransferase (thioester-hydrolysing, 2-carboxyethyl-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.11"^^xsd:string) "2-hydroxyglutarate glyoxylate-lyase (CoA-propanoylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.11"^^xsd:string) "2-hydroxyglutaric synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxyglutarate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.11"^^xsd:string) "hydroxyglutarate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.11"^^xsd:string) "alpha-hydroxyglutarate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.11"^^xsd:string) "2-hydroxyglutaratic synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-deoxy-manno-octulosonate-8-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.45"^^xsd:string) "3-deoxy-D-manno-octulosonate-8-phosphate 8-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.45"^^xsd:string) Annotation( "RHEA:11503"^^xsd:string) "Catalysis of the reaction: 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + H(2)O = 3-deoxy-D-manno-octulosonate + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.21"^^xsd:string) "Catalysis of the reaction: ADP-sugar + H2O = AMP + sugar 1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.21"^^xsd:string) "adenosine diphosphosugar pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) "nucleoside diphosphate-sugar hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.21"^^xsd:string) "ADP-sugar sugarphosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.21"^^xsd:string) "ADP-sugar pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.21"^^xsd:string) "ADPsugar pyrophosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ADP-sugar diphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.19"^^xsd:string) "ABAL dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.19"^^xsd:string) "4-aminobutyraldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aminobutyraldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.19"^^xsd:string) "4-aminobutanal dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.19"^^xsd:string) "gamma-aminobutyraldehyde dehydroganase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.19"^^xsd:string) "4-aminobutanal:NAD+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.19"^^xsd:string) "Catalysis of the reaction: 4-aminobutanal + NAD+ + H2O = 4-aminobutanoate + NADH + 2 H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.1.13"^^xsd:string) "arabinose phosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.13"^^xsd:string) "phosphoarabinoisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.13"^^xsd:string) Annotation( "RHEA:23107"^^xsd:string) "Catalysis of the reaction: D-arabinose 5-phosphate = D-ribulose 5-phosphate + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.13"^^xsd:string) "D-arabinose-5-phosphate aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arabinose-5-phosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.13"^^xsd:string) "D-arabinose-5-phosphate ketol-isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.75"^^xsd:string) "L(+)-1-aminopropan-2-ol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion( "L-aminopropanol dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(R)-aminopropanol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.75"^^xsd:string) "L(+)-1-aminopropan-2-ol-NAD/NADP oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.75"^^xsd:string) "(R)-1-aminopropan-2-ol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.75"^^xsd:string) "1-aminopropan-2-ol-NAD+ dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.75"^^xsd:string) "1-aminopropan-2-ol-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.75"^^xsd:string) Annotation( "RHEA:16520"^^xsd:string) "Catalysis of the reaction: (R)-1-aminopropan-2-ol + NAD(+) = aminoacetone + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.75"^^xsd:string) "DL-1-aminopropan-2-ol: NAD+ dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-cysteine desulfhydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.15"^^xsd:string) "Catalysis of the reaction: D-cysteine + H2O = sulfide + NH3 + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.15"^^xsd:string) "D-cysteine lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.15"^^xsd:string) "D-cysteine sulfide-lyase (deaminating; pyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.15"^^xsd:string) "D-cysteine sulfide-lyase (deaminating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-chloro-D-alanine dehydrochlorinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.5.1.2"^^xsd:string) "3-chloro-D-alanine chloride-lyase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.5.1.2"^^xsd:string) "3-chloro-D-alanine chloride-lyase (deaminating; pyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.5.1.2"^^xsd:string) "beta-chloro-D-alanine dehydrochlorinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.5.1.2"^^xsd:string) "Catalysis of the reaction: 3-chloro-D-alanine + H2O = pyruvate + chloride + NH3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-ribulokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.47"^^xsd:string) "ATP:D-ribulose 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.47"^^xsd:string) "D-ribulokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.47"^^xsd:string) "Catalysis of the reaction: ATP + D-ribulose = ADP + D-ribulose 5-phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.48"^^xsd:string) "NAD-dependent D-galactose dehydrogenase activity"^^xsd:string) AnnotationAssertion( "D-galactose 1-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.48"^^xsd:string) "Catalysis of the reaction: D-galactose + NAD+ = D-galactono-1,4-lactone + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.48"^^xsd:string) "D-galactose:NAD+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.48"^^xsd:string) "beta-galactose dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactose 1-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.48"^^xsd:string) "D-galactose dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acetoin dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:ACETOINDEHYDROG-RXN"^^xsd:string) "Catalysis of the reaction: acetoin + NAD+ = diacetyl + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.5"^^xsd:string) "diacetyl reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.4.2"^^xsd:string) "glutathione-protein disulfide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.2"^^xsd:string) "GSH-insulin transhydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.2"^^xsd:string) "protein-disulfide isomerase/oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.2"^^xsd:string) "protein disulfide transhydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.2"^^xsd:string) "glutathione:protein-disulfide oxidoreductase activity"^^xsd:string) AnnotationAssertion( "glutaredoxin reductase"^^xsd:string) AnnotationAssertion( "protein-disulphide reductase (glutathione) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.2"^^xsd:string) "insulin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.2"^^xsd:string) "protein-disulfide interchange enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.2"^^xsd:string) "Catalysis of the reaction: 2 glutathione + protein-disulfide = oxidized glutathione + protein-dithiol."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.2"^^xsd:string) "thiol-protein disulphide oxidoreductase activity"^^xsd:string) AnnotationAssertion( "glutathione-insulin transhydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.2"^^xsd:string) "protein disulfide reductase (glutathione)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.2"^^xsd:string) "thiol:protein-disulfide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.2"^^xsd:string) "reductase, protein disulfide (glutathione)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.2"^^xsd:string) "glutathione--insulin transhydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-disulfide reductase (glutathione) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.14"^^xsd:string) "glycolate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.14"^^xsd:string) "glycolic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.14"^^xsd:string) "glycolate:acceptor 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.14"^^xsd:string) "glycolate:(acceptor) 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.14"^^xsd:string) Annotation( "RHEA:21267"^^xsd:string) "Catalysis of the reaction: A + glycolate = AH(2) + glyoxylate."^^xsd:string) AnnotationAssertion(rdfs:label "glycolate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.111"^^xsd:string) "imidazol-5-yl lactate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.111"^^xsd:string) "Catalysis of the reaction: (S)-3-(imidazol-5-yl)lactate + NADP+ = 3-(imidazol-5-yl)pyruvate + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.111"^^xsd:string) "(S)-3-(imidazol-5-yl)lactate:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-(imidazol-5-yl)lactate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.68"^^xsd:string) "debranching enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.68"^^xsd:string) "glycogen alpha-1,6-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.68"^^xsd:string) "Catalysis of the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages in glycogen, amylopectin and their beta-limits dextrins."^^xsd:string) AnnotationAssertion(rdfs:label "isoamylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.3"^^xsd:string) "malic oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "malate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.3"^^xsd:string) "FAD-dependent malate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.3"^^xsd:string) "malic dehydrogenase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.3"^^xsd:string) Annotation( "RHEA:10515"^^xsd:string) "Catalysis of the reaction: (S)-malate + O(2) = H(2)O(2) + oxaloacetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.3"^^xsd:string) "(S)-malate:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.7"^^xsd:string) "ATP:D-mannose 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.7"^^xsd:string) "mannokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.7"^^xsd:string) "Catalysis of the reaction: ATP + D-mannose = ADP + D-mannose 6-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "mannokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.7"^^xsd:string) "D-fructose (D-mannose) kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.42"^^xsd:string) "nicotinamide mononucleotide deamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.42"^^xsd:string) "NMN deamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.42"^^xsd:string) "nicotinamide mononucleotide amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nicotinamide-nucleotide amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.42"^^xsd:string) "nicotinamide-D-ribonucleotide amidohydrolase activity"^^xsd:string) AnnotationAssertion( "NMN amidohydrolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.42"^^xsd:string) "Catalysis of the reaction: beta-nicotinamide D-ribonucleotide + H2O = beta-nicotinate D-ribonucleotide + NH3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.14"^^xsd:string) "NMNGhase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.14"^^xsd:string) Annotation( "RHEA:23143"^^xsd:string) "Catalysis of the reaction: H(2)O + nicotinamide mononucleotide = D-ribose 5-phosphate + H(+) + nicotinamide."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.14"^^xsd:string) "NMN glycohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.14"^^xsd:string) "NMNase activity"^^xsd:string) AnnotationAssertion(rdfs:label "NMN nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.14"^^xsd:string) "nicotinamide mononucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.14"^^xsd:string) "nicotinamide-nucleotide phosphoribohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.14"^^xsd:string) "nicotinamide mononucleotide nucleosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.29"^^xsd:string) "amine transaminase activity"^^xsd:string) AnnotationAssertion( "diamine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.29"^^xsd:string) "Catalysis of the reaction: an alpha,omega-diamine + 2-oxoglutarate = an omega-aminoaldehyde + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.29"^^xsd:string) "amine-ketoacid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.29"^^xsd:string) "diamine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "diamine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.29"^^xsd:string) "diamine-ketoglutaric transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.31"^^xsd:string) "pyridoxamine:oxaloacetate aminotransferase activity"^^xsd:string) AnnotationAssertion( "pyridoxamine-oxaloacetate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyridoxamine-oxaloacetate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.31"^^xsd:string) Annotation( "RHEA:10847"^^xsd:string) "Catalysis of the reaction: oxaloacetate + pyridoxamine = L-aspartate + pyridoxal."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.31"^^xsd:string) "pyridoxamine--oxaloacetate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "pyridoxamine-phosphate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.54"^^xsd:string) "Catalysis of the reaction: pyridoxamine 5'-phosphate + 2-oxoglutarate = pyridoxal 5'-phosphate + D-glutamate."^^xsd:string) AnnotationAssertion(rdfs:label "pyridoxamine-phosphate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.54"^^xsd:string) "pyridoxamine 5'-phosphate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.54"^^xsd:string) "pyridoxamine phosphate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.54"^^xsd:string) "pyridoxamine-5'-phosphate:2-oxoglutarate aminotransferase (D-glutamate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.54"^^xsd:string) "pyridoxamine 5'-phosphate-alpha-ketoglutarate transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyruvate synthase activity"^^xsd:string) AnnotationAssertion( "PFOR"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R01196"^^xsd:string) "Catalysis of the reaction: pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.1"^^xsd:string) "pyruvate:ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.1"^^xsd:string) "pyruvate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.1"^^xsd:string) "pyruvic-ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.1"^^xsd:string) "pyruvate synthetase activity"^^xsd:string) AnnotationAssertion( "pyruvate-ferredoxin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.1"^^xsd:string) "pyruvate:ferredoxin 2-oxidoreductase (CoA-acetylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thiamine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.89"^^xsd:string) "thiamin kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.89"^^xsd:string) "thiamin kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.89"^^xsd:string) "thiamin phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.89"^^xsd:string) Annotation( "RHEA:12015"^^xsd:string) "Catalysis of the reaction: ATP + thiamine = ADP + 2 H(+) + thiamine phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.89"^^xsd:string) "ATP:thiamin phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.89"^^xsd:string) "ATP:thiamine phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.38"^^xsd:string) "reductase, trans-enoyl coenzyme A"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.38"^^xsd:string) "NADPH-dependent trans-2-enoyl-CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.38"^^xsd:string) "acyl-CoA:NADP+ trans-2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trans-2-enoyl-CoA reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.38"^^xsd:string) "Catalysis of the reaction: acyl-CoA + NADP+ = trans-2,3-dehydroacyl-CoA + NADPH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-octaprenylphenol hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:2-OCTAPRENYLPHENOL-HYDROX-RXN"^^xsd:string) "Catalysis of the reaction: 2-octaprenylphenol + NADPH + O2 + H+ = 2-octaprenyl-6-hydroxyphenol + NADP+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "methylglyoxal reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methylglyoxal reductase (NADH-dependent) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.78"^^xsd:string) "Catalysis of the reaction: (R)-lactaldehyde + NAD+ = methylglyoxal + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.78"^^xsd:string) "(R)-lactaldehyde:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion( "D-lactaldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3-hydroxyacyl-ACP dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:3-HYDROXYDECANOYL-ACP-DEHYDR-RXN"^^xsd:string) "Catalysis of the reaction: a (3R)-3-hydroxyacyl-[acyl-carrier protein] = H2O + a trans-delta2-enoyl-acyl-[acyl-carrier protein]."^^xsd:string) AnnotationAssertion( "3-hydroxyacyl-[acyl-carrier protein] dehydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "D-lactate dehydratase"^^xsd:string) AnnotationAssertion( "glutathione-independent glyoxalase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.130"^^xsd:string) Annotation( "GOC:mcc"^^xsd:string) Annotation( "MetaCyc:GLYOXIII-RXN"^^xsd:string) Annotation( "PMID:21696459"^^xsd:string) Annotation( "PMID:7848303"^^xsd:string) Annotation( "RHEA:27757"^^xsd:string) Annotation( "http://www.brenda-enzymes.org/php/result_flat.php4?ecno=4.2.1.130"^^xsd:string) "Catalysis of the reaction: methylglyoxal + H2O = D-lactate."^^xsd:string) AnnotationAssertion( "(R)-lactate hydro-lyase"^^xsd:string) AnnotationAssertion(rdfs:label "glyoxalase III activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:THTOREDUCT-RXN"^^xsd:string) "Catalysis of the reaction: tetrahydrothiophene 1-oxide + reduced acceptor = tetrahydrothiophene + acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "tetrahydrothiophene 1-oxide reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dihydroneopterin monophosphate phosphatase activity"^^xsd:string) AnnotationAssertion( "dihydroneopterin monophosphate dephosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:DIHYDRONEOPTERIN-MONO-P-DEPHOS-RXN"^^xsd:string) "Catalysis of the reaction: dihydroneopterin monophosphate = dihydroneopterin + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dihydroneopterin triphosphate pyrophosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN"^^xsd:string) "Catalysis of the reaction: dihydroneopterin triphosphate = dihydroneopterin phosphate + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NADP phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:NADPPHOSPHAT-RXN"^^xsd:string) "Catalysis of the reaction: H2O + NADP+ = NAD+ + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dTDP-4-amino-4,6-dideoxy-D-glucose transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.33"^^xsd:string) "dTDP-4-amino-4,6-dideoxy-D-glucose:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.33"^^xsd:string) "Catalysis of the reaction: dTDP-4-amino-4,6-dideoxy-D-glucose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.33"^^xsd:string) "thymidine diphospho-4-amino-4,6-dideoxyglucose aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.33"^^xsd:string) "thymidine diphospho-4-keto-6-deoxy-D-glucose transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.33"^^xsd:string) "thymidine diphospho-4-keto-6-deoxy-D-glucose-glutamic transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.33"^^xsd:string) "TDP-4-oxo-6-deoxy-D-glucose transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.33"^^xsd:string) "TDP-4-keto-6-deoxy-D-glucose transaminase activity"^^xsd:string) AnnotationAssertion( "dTDP-4-amino-4,6-dideoxy-D-glucose aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.33"^^xsd:string) "thymidine diphospho-4-amino-6-deoxyglucose aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.59"^^xsd:string) "thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.59"^^xsd:string) "dTDP-4,6-dideoxy-D-galactose:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.59"^^xsd:string) Annotation( "RHEA:10371"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-D-galactose = L-glutamate + dTDP-4-dehydro-6-deoxy-D-galactose."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.59"^^xsd:string) "dTDP-4-amino-4,6-dideoxygalactose aminotransferase activity"^^xsd:string) AnnotationAssertion( "dTDP-fucosamine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.59"^^xsd:string) "thymidine diphosphoaminodideoxygalactose aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dTDP-4-amino-4,6-dideoxygalactose transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "halohydrin hydrogen-halide-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8017917"^^xsd:string) "Catalysis of the reaction: a halohydrin = an epoxide + a hydrogen halide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when histamine has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion(rdfs:label "histamine-gated chloride channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acyl-CoA N-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of an acyl group from acyl-CoA to a nitrogen atom on an acceptor molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mcc"^^xsd:string) Annotation( "PMID:8166646"^^xsd:string) "Catalysis of the transfer of a mannose residue to an oligosaccharide, forming a beta-(1->4) linkage."^^xsd:string) AnnotationAssertion(rdfs:label "beta-1,4-mannosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of cellobiose from one side of the membrane to the other. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose."^^xsd:string) AnnotationAssertion( "cellobiose permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "cellobiose transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sorbose porter activity"^^xsd:string) AnnotationAssertion(rdfs:label "sorbose transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of sorbose from one side of the membrane to the other. Sorbose is the ketohexose xylo-2-hexulose; L-sorbose is formed by bacterial oxidation of sorbitol. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "galactosamine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of galactosamine from one side of the membrane to the other. Galactosamine is an aminodeoxysugar; D-galactosamine is a constituent of some glycolipids and glycosaminoglycans, commonly as its N-acetyl derivative."^^xsd:string) AnnotationAssertion( "galactosamine porter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "transmembrane receptor protein phosphatase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP."^^xsd:string) AnnotationAssertion(rdfs:label "transmembrane receptor protein kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecule."^^xsd:string) AnnotationAssertion(rdfs:label "carbohydrate kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "nucleotide kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a phosphate group, usually from ATP, to an amino acid substrate."^^xsd:string) AnnotationAssertion(rdfs:label "amino acid kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carbohydrate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: carbohydrate phosphate + H2O = carbohydrate + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a phosphate group, usually from ATP or GTP, to a nucleobase, nucleoside, nucleotide or polynucleotide substrate."^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "nucleobase, nucleoside, nucleotide kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nucleobase-containing compound kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nucleoside kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: ATP + nucleoside = ADP + nucleoside monophosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "kinase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatase regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Increases the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule."^^xsd:string) AnnotationAssertion(rdfs:label "kinase activator activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "kinase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stops, prevents or reduces the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Stops, prevents or reduces the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space."^^xsd:string) AnnotationAssertion(rdfs:label "intermediate filament binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "centromeric DNA binding"^^xsd:string) AnnotationAssertion( "centromere binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "SO:0000577"^^xsd:string) "Interacting selectively and non-covalently with a centromere, a region of chromosome where the spindle fibers attach during mitosis and meiosis."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2, in a reaction that involves the opening of a ring."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the removal of an amino group from a substrate, producing ammonia (NH3)."^^xsd:string) AnnotationAssertion(rdfs:label "deaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "oxalic acid transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of oxalate from one side of the membrane to the other. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals."^^xsd:string) AnnotationAssertion(rdfs:label "oxalate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of a toxin into, out of or within a cell, or between cells. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism."^^xsd:string) AnnotationAssertion(rdfs:label "toxin transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ferric-vibriobactin transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of ferric-vibriobactin ions from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "protein-arginine delta-N-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-arginine N5-methyltransferase activity"^^xsd:string) AnnotationAssertion( "type IV PRMT activity"^^xsd:string) AnnotationAssertion( "type IV protein arginine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9873020"^^xsd:string) "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the delta-nitrogen atom of peptidyl-arginine residues."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein-cysteine S-myristoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a myristoyl group to a sulfur atom on a cysteine residue of a protein molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "protein-cysteine S-palmitoleyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-cysteine S-palmitoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.225"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) "Catalysis of the transfer of a palmitoyl group to a sulfur atom on the cysteine of a protein molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an acyl group to a sulfur atom on the cysteine of a protein molecule."^^xsd:string) AnnotationAssertion(rdfs:label "protein-cysteine S-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.33"^^xsd:string) Annotation( "RHEA:20196"^^xsd:string) "Catalysis of the reaction: (R)-mevalonate + NADP(+) = H(+) + mevaldate + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.33"^^xsd:string) "mevaldate (reduced nicotinamide adenine dinucleotide phosphate) reductase"^^xsd:string) AnnotationAssertion(rdfs:label "mevaldate reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.33"^^xsd:string) "(R)-mevalonate:NADP+ oxidoreductase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.32"^^xsd:string) Annotation( "RHEA:13224"^^xsd:string) "Catalysis of the reaction: (R)-mevalonate + NAD(+) = H(+) + mevaldate + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "mevaldate reductase (NAD+) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "FC receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "immunoglobulin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0198547684"^^xsd:string) "Combining with the Fc region of an immunoglobulin protein and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "IgA receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "IgE receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "high affinity IgE receptor activity"^^xsd:string) AnnotationAssertion( "high affinity Fc receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with high affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "low affinity Fc receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "low affinity IgE receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with low affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "IgG receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "high affinity IgG receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with high affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "high affinity Fc receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with low affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "low affinity Fc receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "low affinity IgG receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "FAT10 ligase activity"^^xsd:string) AnnotationAssertion( "FAT10 conjugating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12826404"^^xsd:string) "Catalysis of the covalent attachment of the ubiquitin-like protein FAT10 to other proteins."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Atg8 conjugating enzyme activity"^^xsd:string) AnnotationAssertion( "APG8 conjugating enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "Atg8 ligase activity"^^xsd:string) AnnotationAssertion( "APG8 ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12826404"^^xsd:string) "Catalysis of the covalent attachment of the ubiquitin-like protein Atg8 to substrate molecules; phosphatidylethanolamine is a known substrate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "APG12 ligase activity"^^xsd:string) AnnotationAssertion( "Atg12 conjugating enzyme activity"^^xsd:string) AnnotationAssertion( "APG12 conjugating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12826404"^^xsd:string) "Catalysis of the covalent attachment of the ubiquitin-like protein Atg12 to other proteins."^^xsd:string) AnnotationAssertion(rdfs:label "Atg12 ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond."^^xsd:string) AnnotationAssertion(rdfs:label "APG12 activating enzyme activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "APG8 activating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond."^^xsd:string) AnnotationAssertion( "APG7"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "FAT10 activating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NEDD8 activating enzyme activity"^^xsd:string) AnnotationAssertion( "RUB1 activating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12646924"^^xsd:string) "Catalysis of the initiation of the NEDD8 (RUB1) conjugation cascade."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "UBE1L"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond."^^xsd:string) AnnotationAssertion(rdfs:label "ISG15 activating enzyme activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "small conjugating protein-specific protease activity"^^xsd:string) AnnotationAssertion( "ubiquitin-like-protein-specific protease activity"^^xsd:string) AnnotationAssertion( "ubiquitin-like specific protease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ma"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of peptide or isopeptide bonds within small proteins such as ubiquitin or ubiquitin-like proteins (e.g. APG8, ISG15, NEDD8, SUMO), or between the small protein and a larger protein to which it has been conjugated."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of NEDD8, a small ubiquitin-related modifier, from previously neddylated substrates."^^xsd:string) AnnotationAssertion(rdfs:label "NEDD8-specific protease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "deneddylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ISG15-specific protease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of ISG15, a small ubiquitin-related modifier, from previously modified substrates."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "APG8-PE hydrolase"^^xsd:string) AnnotationAssertion(rdfs:label "APG8-specific protease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:rn"^^xsd:string) Annotation( "PMID:10806345"^^xsd:string) Annotation( "PMID:10884686"^^xsd:string) "Catalysis of ATP-dependent isopeptide bond formation between the carboxy-terminal residues of a small conjugating protein such as ubiquitin or a ubiquitin-like protein, and a substrate lysine residue. This function may be performed alone or in conjunction with an E3, ubiquitin-like protein ligase."^^xsd:string) AnnotationAssertion( "ubiquitin-like-protein ligase activity"^^xsd:string) AnnotationAssertion( "E2"^^xsd:string) AnnotationAssertion( "ubiquitin-like conjugating enzyme activity"^^xsd:string) AnnotationAssertion( "small protein conjugating enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "small conjugating protein ligase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of ATP-dependent isopeptide bond formation between the carboxy-terminal residues of the small ubiquitin-related modifier NEDD8 and a substrate lysine residue."^^xsd:string) AnnotationAssertion( "RUB1 conjugating enzyme activity"^^xsd:string) AnnotationAssertion( "Hub1 conjugating enzyme activity"^^xsd:string) AnnotationAssertion( "NEDD8 conjugating enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "NEDD8 ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "SUMO ligase activity"^^xsd:string) AnnotationAssertion( "SMT3 conjugating enzyme"^^xsd:string) AnnotationAssertion( "SUMO conjugating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rn"^^xsd:string) Annotation( "PMID:11031248"^^xsd:string) Annotation( "PMID:11265250"^^xsd:string) "Catalysis of ATP-dependent isopeptide bond formation between the carboxy-terminal glycine residues of the small ubiquitin-related modifier SUMO and a substrate lysine residue, leading to the formation of predominately monosumoylated proteins with modified function."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "interferon-stimulated gene-15 carrier activity"^^xsd:string) AnnotationAssertion(rdfs:label "ISG15 carrier activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "http://www.copewithcytokines.de/"^^xsd:string) "Catalysis of the transfer of ISG15 (interferon-stimulated gene-15) from one side of the membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "procollagen-proline 3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.7"^^xsd:string) "prolyl 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.7"^^xsd:string) "Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-3-hydroxy-L-proline + succinate + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.7"^^xsd:string) "prolyl-4-hydroxyprolyl-glycyl-peptide, 2-oxoglutarate: oxygen oxidoreductase, 3-hydroxylating activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.7"^^xsd:string) "procollagen-proline,2-oxoglutarate 3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.7"^^xsd:string) "protocollagen proline 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.7"^^xsd:string) "proline,2-oxoglutarate 3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.7"^^xsd:string) "procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.2"^^xsd:string) Annotation( "EC:1.14.11.7"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-hydroxy-L-proline + succinate + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "procollagen-proline dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tubulin N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.108"^^xsd:string) "TAT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.108"^^xsd:string) "alpha-tubulin acetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.108"^^xsd:string) "alpha-tubulin acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.108"^^xsd:string) "alpha-tubulin N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.108"^^xsd:string) "acetyl-CoA:alpha-tubulin-lysine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.108"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + (alpha-tubulin) L-lysine = CoA + (alpha-tubulin) N6-acetyl-L-lysine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.108"^^xsd:string) "acetyl-CoA:alpha-tubulin-L-lysine 6-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.108"^^xsd:string) "acetyl-CoA:alpha-tubulin-L-lysine N6-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.108"^^xsd:string) "tubulin acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "bromoperoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.10"^^xsd:string) "Catalysis of the reaction: 2 R-H + 2 bromide + hydrogen peroxide = 2 R-Br + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide."^^xsd:string) AnnotationAssertion(rdfs:label "bromide peroxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.15"^^xsd:string) "Catalysis of the reaction: N-acyl-L-aspartate + H2O = a fatty acid anion + L-aspartate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.15"^^xsd:string) "aminoacylase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.15"^^xsd:string) "acylase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.15"^^xsd:string) "N-acyl-L-aspartate amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.15"^^xsd:string) "N-acetylaspartate amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aspartoacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.15"^^xsd:string) "acetyl-aspartic deaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "polyamine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with polyamines, organic compounds containing two or more amino groups."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with spermidine, N-(3-aminopropyl)-1,4-diaminobutane."^^xsd:string) AnnotationAssertion(rdfs:label "spermidine binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "putrescine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with putrescine, 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cocaine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with cocaine (2-beta-carbomethoxy-3-beta-benzoxytropane), an alkaloid obtained from dried leaves of the South American shrub Erythroxylon coca or by chemical synthesis."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cytochrome P450 activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with oxygen (O2)."^^xsd:string) AnnotationAssertion( "cytochrome P450"^^xsd:string) AnnotationAssertion(rdfs:label "oxygen binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxygen sensor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of oxygen (O2)."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "aspartic-type endopeptidase inhibitor activity"^^xsd:string) AnnotationAssertion( "aspartic protease inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "cation ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in)."^^xsd:string) AnnotationAssertion( "plasma membrane cation-transporting ATPase"^^xsd:string) AnnotationAssertion(rdfs:label "cation-transporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phospholipase A2 inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Stops, prevents or reduces the activity of the enzyme phospholipase A2."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "neurotrophin TRK receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "Interacting selectively and non-covalently with any growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate."^^xsd:string) AnnotationAssertion(rdfs:label "growth factor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "isoprenoid binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "vitamin A1 binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:50211"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Interacting selectively and non-covalently with retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation."^^xsd:string) AnnotationAssertion(rdfs:label "retinol binding"^^xsd:string) AnnotationAssertion( "vitamin A1 alcohol binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."^^xsd:string) AnnotationAssertion(rdfs:label "vitamin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with ribosomal RNA."^^xsd:string) AnnotationAssertion(rdfs:label "rRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stops, prevents, or reduces the activity of a calcium channel."^^xsd:string) AnnotationAssertion(rdfs:label "calcium channel inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Interacting selectively and non-covalently with an immunoglobulin of an IgA isotype."^^xsd:string) AnnotationAssertion(rdfs:label "IgA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "IgE binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Interacting selectively and non-covalently with an immunoglobulin of the IgE isotype."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Interacting selectively and non-covalently with an immunoglobulin of an IgG isotype."^^xsd:string) AnnotationAssertion(rdfs:label "IgG binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "immunoglobulin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ma"^^xsd:string) "Interacting selectively and non-covalently with an immunoglobulin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chloride channel inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stops, prevents, or reduces the activity of a chloride channel."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "potassium channel inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stops, prevents, or reduces the activity of a potassium channel."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "sodium channel inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stops, prevents, or reduces the activity of a sodium channel."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.2.12"^^xsd:string) Annotation( "RHEA:16228"^^xsd:string) "Catalysis of the reaction: 1,8-diazacyclotetradecane-2,9-dione + H(2)O = N-(6-aminohexanoyl)-6-aminohexanoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.12"^^xsd:string) "1,8-diazacyclotetradecane-2,9-dione lactamhydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "6-aminohexanoate-cyclic-dimer hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.46"^^xsd:string) "Catalysis of the reaction: N-(6-aminohexanoyl)-6-aminohexanoate + H2O = 2 6-aminohexanoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.46"^^xsd:string) "6-aminohexanoic acid oligomer hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "6-aminohexanoate-dimer hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.46"^^xsd:string) "N-(6-aminohexanoyl)-6-aminohexanoate amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein kinase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "protein phosphatase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "kinesin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) Annotation( "PMID:8606779"^^xsd:string) "Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12495622"^^xsd:string) "The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to mitochondria."^^xsd:string) AnnotationAssertion(rdfs:label "kinesin-associated mitochondrial adaptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with any enzyme."^^xsd:string) AnnotationAssertion(rdfs:label "enzyme binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "kinase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate."^^xsd:string) AnnotationAssertion(rdfs:label "protein kinase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with any phosphatase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with any protein phosphatase."^^xsd:string) AnnotationAssertion(rdfs:label "protein phosphatase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with a specific domain of a protein."^^xsd:string) AnnotationAssertion( "protein domain-specific binding"^^xsd:string) AnnotationAssertion(rdfs:label "protein domain specific binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a syntaxin, a SNAP receptor involved in the docking of synaptic vesicles at the presynaptic zone of a synapse."^^xsd:string) AnnotationAssertion( "syntaxin-13 binding"^^xsd:string) AnnotationAssertion( "syntaxin-6 binding"^^xsd:string) AnnotationAssertion( "syntaxin-2 binding"^^xsd:string) AnnotationAssertion(rdfs:label "syntaxin binding"^^xsd:string) AnnotationAssertion( "syntaxin-5 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.43"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Modification of the activity of the enzyme [pyruvate dehydrogenase (lipoamide)] phosphatase."^^xsd:string) AnnotationAssertion(rdfs:label "[pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity"^^xsd:string) AnnotationAssertion( "[pyruvate dehydrogenase (lipoamide)] phosphatase, intrinsic regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "The action of a molecule that contributes to the structural integrity of the myelin sheath of a nerve."^^xsd:string) AnnotationAssertion(rdfs:label "structural constituent of myelin sheath"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cyclin-dependent protein kinase activating kinase, intrinsic catalyst activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyclin-dependent protein kinase activating kinase activity"^^xsd:string) AnnotationAssertion( "CAK"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; increases the activity of a cyclin-dependent protein kinase (CDK)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclin-dependent protein kinase activating kinase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Modulation of the activity of the enzyme cyclin-dependent protein kinase activating kinase."^^xsd:string) AnnotationAssertion( "cyclin-dependent protein kinase activating kinase, intrinsic regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:rn"^^xsd:string) Annotation( "PMID:10187858"^^xsd:string) Annotation( "PMID:11265250"^^xsd:string) "Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond."^^xsd:string) AnnotationAssertion( "SMT3 activating enzyme"^^xsd:string) AnnotationAssertion( "SUMO E1 activator enzyme"^^xsd:string) AnnotationAssertion(rdfs:label "SUMO activating enzyme activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "ISBN:0198599471"^^xsd:string) "Interacting selectively and non-covalently with a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity."^^xsd:string) AnnotationAssertion( "IL binding"^^xsd:string) AnnotationAssertion(rdfs:label "cytokine binding"^^xsd:string) AnnotationAssertion( "interleukin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chemokine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) Annotation( "PMID:12183377"^^xsd:string) Annotation( "http://en.wikipedia.org/wiki/Chemokine"^^xsd:string) "Interacting selectively and non-covalently with a chemokine. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "C-C chemokine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a C-X-C chemokine; C-X-C chemokines have a single amino acid between the first two cysteines of the characteristic four cysteine motif."^^xsd:string) AnnotationAssertion(rdfs:label "C-X-C chemokine binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-8 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-8."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-8 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "C-X3-C chemokine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a C-X3-C chemokine; C-X3-C chemokines have three amino acids between the first two cysteines of the characteristic four-cysteine motif."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interferon binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9607096"^^xsd:string) Annotation( "Wikipedia:Interferon"^^xsd:string) "Interacting selectively and non-covalently with an interferon, a protein produced by the immune systems of many animals in response to a challenge by a foreign agent."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IFN binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "interferon-tau binding"^^xsd:string) AnnotationAssertion( "interferon-kappa binding"^^xsd:string) AnnotationAssertion(rdfs:label "type I interferon binding"^^xsd:string) AnnotationAssertion( "interferon-epsilon binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "type I IFN binding"^^xsd:string) AnnotationAssertion( "interferon-omega binding"^^xsd:string) AnnotationAssertion( "interferon-delta binding"^^xsd:string) AnnotationAssertion( "interferon-zeta binding"^^xsd:string) AnnotationAssertion( "interferon-alpha/beta binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0126896631"^^xsd:string) Annotation( "PMID:15546383"^^xsd:string) Annotation( "PMID:16681834"^^xsd:string) "Interacting selectively and non-covalently with a type I interferon. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families."^^xsd:string) AnnotationAssertion( "interferon-beta binding"^^xsd:string) AnnotationAssertion( "interferon-alpha binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IFNG binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15546383"^^xsd:string) Annotation( "PR:000024990"^^xsd:string) "type II interferon binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PR:000000017"^^xsd:string) "IFN-gamma binding"^^xsd:string) AnnotationAssertion(rdfs:label "interferon-gamma binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0126896631"^^xsd:string) Annotation( "PMID:15546383"^^xsd:string) Annotation( "PR:000000017"^^xsd:string) "Interacting selectively and non-covalently with interferon-gamma. Interferon gamma is the only member of the type II interferon found so far."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with interleukin-1."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-1 binding"^^xsd:string) AnnotationAssertion( "IL-1 binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-10 binding"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-10 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-10."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-11 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-11."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-11 binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-12."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-12 binding"^^xsd:string) AnnotationAssertion( "IL-12 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-13 binding"^^xsd:string) AnnotationAssertion( "IL-13 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-13."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-14."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-14 binding"^^xsd:string) AnnotationAssertion( "IL-14 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-17 binding"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-17 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with any member of the interleukin-17 family of cytokines."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-2 binding"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-2 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-2."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-21."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-21 binding"^^xsd:string) AnnotationAssertion( "IL-21 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-3."^^xsd:string) AnnotationAssertion( "IL-3 binding"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-3 binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-4 binding"^^xsd:string) AnnotationAssertion( "IL-4 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-4."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-5 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-5."^^xsd:string) AnnotationAssertion( "IL-5 binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-6 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-6."^^xsd:string) AnnotationAssertion( "IL-6 binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-7 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-7."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-7 binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-9."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-9 binding"^^xsd:string) AnnotationAssertion( "IL-9 binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ma"^^xsd:string) "Interacting selectively and non-covalently with diacylglycerol, a diester of glycerol and two fatty acids."^^xsd:string) AnnotationAssertion(rdfs:label "diacylglycerol binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "heme binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:30413"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring."^^xsd:string) AnnotationAssertion( "haem binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient."^^xsd:string) AnnotationAssertion(rdfs:label "passive transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "active carrier activity"^^xsd:string) AnnotationAssertion(rdfs:label "active transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction."^^xsd:string) AnnotationAssertion( "pump activity"^^xsd:string) AnnotationAssertion( "permease activity"^^xsd:string) AnnotationAssertion( "carrier activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ionophore"^^xsd:string) AnnotationAssertion(rdfs:label "mobile ion carrier activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "This is a type of carrier produced by bacteria. It enables passive transport by shielding the ion that is being transported from the lipid membrane. It carries an ion across the membrane by enclosing the ion and travelling across the membrane. It does not form a fully open pore across the membrane."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Enables the active transport of a solute across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged."^^xsd:string) AnnotationAssertion( "porter"^^xsd:string) AnnotationAssertion(rdfs:label "membrane potential driven uniporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a single solute from one side of the membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged."^^xsd:string) AnnotationAssertion( "porters"^^xsd:string) AnnotationAssertion(rdfs:label "facilitated diffusion"^^xsd:string) AnnotationAssertion( "uniporter activity z"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sodium ion uniporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the active transport of a sodium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "potassium ion uniporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the active transport of a potassium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the active transport of a potassium ion across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy."^^xsd:string) AnnotationAssertion(rdfs:label "potassium ion symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "potassium ion antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the active transport of a potassium ion across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:sart"^^xsd:string) "ionotropic neurotransmitter receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion(rdfs:label "transmitter-gated ion channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a solute by a channel that opens in response to phosphorylation of one of its constituent parts."^^xsd:string) AnnotationAssertion(rdfs:label "phosphorylation-gated channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "non-gated, wide pore channel activity"^^xsd:string) AnnotationAssertion(rdfs:label "wide pore channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Enables the transport of a solute across a membrane via a large pore, un-gated channel. Examples include gap junctions, which transport substances from one cell to another; and porins which transport substances in and out of bacteria, mitochondria and chloroplasts."^^xsd:string) AnnotationAssertion( "gap junction activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Enables the transport of a solute across a membrane via a narrow pore channel that opens in response to a particular stimulus."^^xsd:string) AnnotationAssertion( "ion channels"^^xsd:string) AnnotationAssertion(rdfs:label "narrow pore, gated channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion(rdfs:label "voltage-gated channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mechanically gated channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a mechanical stress."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion(rdfs:label "ligand-gated channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a solute by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion( "extracellular substance gated channel activity"^^xsd:string) AnnotationAssertion(rdfs:label "transmitter-gated channel activity"^^xsd:string) AnnotationAssertion( "neurotransmitter-gated channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "gated channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "substrate-specific channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ion gated channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific ion stimulus."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "leak channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Enables the transport of a solute across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "potassium ion leak channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transport of a potassium ion across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "narrow pore channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Enables the transport of a solute across a membrane via a narrow pore channel that may be gated or ungated."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion(rdfs:label "voltage-gated cation channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a cation by a channel that opens when acetylcholine has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion(rdfs:label "acetylcholine-gated cation channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutamate-gated calcium ion channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a cation by a channel that opens when serotonin has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion(rdfs:label "serotonin-gated cation channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GABA-gated chloride ion channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when GABA has been bound by the channel complex or one of its constituent parts."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycine-gated chloride ion channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when glycine has been bound by the channel complex or one of its constituent parts."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "active ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glucose PTS transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + glucose(out) = protein histidine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbitol(out) = protein histidine + sorbitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport."^^xsd:string) AnnotationAssertion( "sorbitol PTS transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-N(PI)-phosphohistidine-sorbitol phosphotransferase system transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Enables the transfer of a substance from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of alanine from one side of a membrane to the other. Alanine is 2-aminopropanoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "alanine transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transmembrane transfer of a solute by a channel that opens in response to dephosphorylation of one of its constituent parts."^^xsd:string) AnnotationAssertion(rdfs:label "dephosphorylation-gated channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:5"^^xsd:string) "Enables electron flow across a biological membrane, from donors localized on one side of the membrane to acceptors localized on the other side. These systems contribute to or subtract from the membrane potential, depending on the direction of electron flow. They are therefore important to cellular energetics."^^xsd:string) AnnotationAssertion(rdfs:label "transmembrane electron transfer carrier"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "transmembrane one-electron transfer carrier"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:5.B"^^xsd:string) "Enables transfer of one electron across a membrane."^^xsd:string) AnnotationAssertion(rdfs:label "transmembrane 1-electron transfer carrier"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "TC:5.A"^^xsd:string) "Enables transfer of two electrons across a membrane."^^xsd:string) AnnotationAssertion(rdfs:label "transmembrane 2-electron transfer carrier"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "transmembrane two-electron transfer carrier"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity"^^xsd:string) AnnotationAssertion( "lactose PTS transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + lactose(out) = protein histidine + lactose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "mannose PTS transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannose(out) = protein histidine + mannose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport."^^xsd:string) AnnotationAssertion(rdfs:label "protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbose(out) = protein histidine + sorbose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport."^^xsd:string) AnnotationAssertion(rdfs:label "protein-N(PI)-phosphohistidine-sorbose phosphotransferase system transporter activity"^^xsd:string) AnnotationAssertion( "sorbose PTS transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "mannitol PTS transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannitol(out) = protein histidine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein-N(PI)-phosphohistidine-maltose phosphotransferase system transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + maltose(out) = protein histidine + maltose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport."^^xsd:string) AnnotationAssertion( "maltose PTS transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + cellobiose(out) = protein histidine + cellobiose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport."^^xsd:string) AnnotationAssertion(rdfs:label "protein-N(PI)-phosphohistidine-cellobiose phosphotransferase system transporter activity"^^xsd:string) AnnotationAssertion( "cellobiose PTS transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "galactitol PTS transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactitol(out) = protein histidine + galactitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport."^^xsd:string) AnnotationAssertion(rdfs:label "protein-N(PI)-phosphohistidine-galactitol phosphotransferase system transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactosamine(out) = protein histidine + galactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport."^^xsd:string) AnnotationAssertion( "galactosamine PTS transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-N(PI)-phosphohistidine-galactosamine phosphotransferase system transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "fructose PTS transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + fructose(out) = protein histidine + fructose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sucrose PTS transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sucrose(out) = protein histidine + sucrose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein-N(PI)-phosphohistidine-trehalose phosphotransferase system transporter activity"^^xsd:string) AnnotationAssertion( "trehalose PTS transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + trehalose(out) = protein histidine + trehalose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "N-acetylglucosamine PTS transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-N(PI)-phosphohistidine-N-acetylglucosamine phosphotransferase system transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylglucosamine(out) = protein histidine + N-acetylglucosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein-N(PI)-phosphohistidine-N-acetylgalactosamine phosphotransferase system transporter activity"^^xsd:string) AnnotationAssertion( "N-acetylgalactosamine PTS transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylgalactosamine(out) = protein histidine + N-acetylgalactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "beta-glucoside PTS transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport."^^xsd:string) AnnotationAssertion(rdfs:label "protein-N(PI)-phosphohistidine-beta-glucoside phosphotransferase system transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "zinc efflux transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane."^^xsd:string) AnnotationAssertion( "zinc efflux permease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a macromolecule from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "macromolecule transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bacteriocin transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a bacteriocin from one side of the membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Enables transport of a solute across a membrane. This kind of transporter interacts much more weakly with the solute than the carrier does. It is an aqueous pore that extends across the membrane. It may change from closed to open and back. It transports faster than a carrier. It is always passive."^^xsd:string) AnnotationAssertion( "ionophore activity"^^xsd:string) AnnotationAssertion(rdfs:label "channel-forming ionophore activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of serine from one side of a membrane to the other. Serine is 2-amino-3-hydroxypropanoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "serine transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage."^^xsd:string) AnnotationAssertion(rdfs:label "inorganic cation transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "di-, tri-valent inorganic cation transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "substrate-specific transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion(rdfs:label "substrate-specific transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "low-affinity tryptophan transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "low-affinity tryptophan permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the low-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "intermdiate conductance KCa channels "^^xsd:string) AnnotationAssertion( "IK calcium-activated potassium channel activity "^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "OMIM:602754"^^xsd:string) "Catalysis of the transmembrane transfer of potassium by a channel with a unit conductance of 20 to 85 picoSiemens that opens in response to stimulus by internal calcium ions. Intermediate conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism."^^xsd:string) AnnotationAssertion( "IK KCa channels"^^xsd:string) AnnotationAssertion(rdfs:label "Intermediate conductance calcium-activated potassium channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the transfer of a peptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement."^^xsd:string) AnnotationAssertion( "hydrogen/oligopeptide symporter"^^xsd:string) AnnotationAssertion(rdfs:label "proton-dependent peptide secondary active transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "MHC protein complex binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_signal"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with the major histocompatibility complex."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "MHC class I protein complex binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_signal"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with the class I major histocompatibility complex."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "MHC class Ib protein complex binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_signal"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with the class Ib major histocompatibility complex."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "MHC class II protein complex binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_signal"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with the class II major histocompatibility complex."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "MHC class I protein binding, via antigen binding groove"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_signal"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with major histocompatibility complex class I molecules via the antigen binding groove."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_signal"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with major histocompatibility complex class I molecules via the lateral surface."^^xsd:string) AnnotationAssertion(rdfs:label "MHC class I protein binding, via lateral surface"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_signal"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with major histocompatibility complex class Ib molecules."^^xsd:string) AnnotationAssertion(rdfs:label "MHC class Ib protein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_signal"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with major histocompatibility complex class Ib molecules via the antigen binding groove."^^xsd:string) AnnotationAssertion(rdfs:label "MHC class Ib protein binding, via antigen binding groove"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mtg_signal"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with major histocompatibility complex class Ib molecules via the lateral surface."^^xsd:string) AnnotationAssertion(rdfs:label "MHC class Ib protein binding, via lateral surface"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "extracellular matrix structural constituent conferring tensile strength"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0815316194"^^xsd:string) "A constituent of the extracellular matrix that enables the matrix to resist longitudinal stress."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0815316194"^^xsd:string) "A constituent of the extracellular matrix that enables the matrix to resist compressive forces; often a proteoglycan."^^xsd:string) AnnotationAssertion(rdfs:label "extracellular matrix structural constituent conferring compression resistance"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "elastin"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0815316194"^^xsd:string) "A component of the extracellular matrix that enables the matrix to recoil after transient stretching."^^xsd:string) AnnotationAssertion(rdfs:label "extracellular matrix constituent conferring elasticity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.99.3"^^xsd:string) "methylamine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.99.3"^^xsd:string) "primary-amine:(acceptor) oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.99.3"^^xsd:string) "amine: (acceptor) oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(rdfs:label "amine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.99.3"^^xsd:string) "primary-amine:acceptor oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.99.3"^^xsd:string) "Catalysis of the reaction: R-CH2-NH2 + H2O + acceptor = R-CHO + NH3 + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.99.3"^^xsd:string) "primary-amine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.99.3"^^xsd:string) "MADH activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.9.2"^^xsd:string) "aromatic amine dehydrogenase (azurin) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.9.2"^^xsd:string) "tyramine dehydrogenase (azurin) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.9.2"^^xsd:string) "aralkylamine:(azurin) oxidoreductase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.9.2"^^xsd:string) "arylamine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.9.2"^^xsd:string) "dehydrogenase, arylamine (azurin) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.9.2"^^xsd:string) "Catalysis of the reaction: H(2)O + arCH(2)NH(2) + 2 azurin = 2 reduced azurin + ArCHO + NH(3). The symbol arCH(2)NH(2) represents an aralkylamine and ArCHO is an aryl aldehyde."^^xsd:string) AnnotationAssertion(rdfs:label "aralkylamine dehydrogenase (azurin) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.37"^^xsd:string) "malic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.37"^^xsd:string) "NAD-dependent malate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-malate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.37"^^xsd:string) "malate (NAD) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.37"^^xsd:string) "NAD-specific malate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.37"^^xsd:string) "Catalysis of the reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+."^^xsd:string) AnnotationAssertion( "NAD-L-malate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.37"^^xsd:string) "MDH"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.37"^^xsd:string) "NAD-linked malate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.37"^^xsd:string) "(S)-malate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.37"^^xsd:string) "NAD-malate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.37"^^xsd:string) "L-malate-NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.37"^^xsd:string) "malic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.37"^^xsd:string) "NAD-dependent malic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.37"^^xsd:string) "NAD-malic dehydrogenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "HLA-A specific inhibitory MHC class I receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:11929129"^^xsd:string) Annotation( "PMID:9368779"^^xsd:string) "Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "HLA-A specific activating MHC class I receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:11929129"^^xsd:string) Annotation( "PMID:9368779"^^xsd:string) "Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that activates a lymphocyte."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "HLA-B specific inhibitory MHC class I receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:11929129"^^xsd:string) Annotation( "PMID:9368779"^^xsd:string) "Combining with a MHC class I molecule of the HLA-B subclass to mediate signaling that inhibits activation of a lymphocyte."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "HLA-C specific inhibitory MHC class I receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:11929129"^^xsd:string) Annotation( "PMID:9368779"^^xsd:string) "Combining with a MHC class I molecule of the HLA-C subclass to mediate signaling that inhibits activation of a lymphocyte."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glial cell line-derived neurotrophic factor receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:11476867"^^xsd:string) "A growth factor that binds selectively and non-covalently to glial cell line-derived neurotrophic factor receptors."^^xsd:string) AnnotationAssertion( "glial cell line-derived neurotrophic factor receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.155"^^xsd:string) "UDP-N-acetylglucosamine:alpha-mannoside-beta-1,6 N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.155"^^xsd:string) "N-acetylglucosaminyltransferase V activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.155"^^xsd:string) "alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.155"^^xsd:string) "UDP-N-acetyl-D-glucosamine:6-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 6-beta-N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion( "alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion( "alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.155"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl,1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-(N-acetyl-beta-D-glucosaminyl-1,6)-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R. Only branched mannose glycopeptides with non-reducing N-acetylglucosamine terminal residues act as acceptors."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.155"^^xsd:string) "uridine diphosphoacetylglucosamine-alpha-mannoside beta1->6-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.155"^^xsd:string) "UDP-N-acetylglucosamine:alpha-mannoside-beta1,6 N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.155"^^xsd:string) "GnTV activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.155"^^xsd:string) "uridine diphosphoacetylglucosamine-alpha-mannoside beta-1->6-acetylglucosaminyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "manganese binding"^^xsd:string) AnnotationAssertion(rdfs:label "manganese ion binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with manganese (Mn) ions."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with molybdenum (Mo) ions."^^xsd:string) AnnotationAssertion(rdfs:label "molybdenum ion binding"^^xsd:string) AnnotationAssertion( "molybdenum binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9915832"^^xsd:string) "Interacting selectively and non-covalently with the peripheral benzodiazepine receptor (PBR)."^^xsd:string) AnnotationAssertion( "benzodiazepine receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "benzodiazepine receptor binding"^^xsd:string) AnnotationAssertion( "diazepam binding inhibitor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.26"^^xsd:string) "UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.26"^^xsd:string) "uridine diphosphoxylose-core protein beta-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.26"^^xsd:string) "UDP-D-xylose:core protein xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.26"^^xsd:string) "Catalysis of the transfer of a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.26"^^xsd:string) "UDP-xylose-core protein beta-D-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.26"^^xsd:string) "uridine diphosphoxylose-protein xylosyltransferase activity"^^xsd:string) AnnotationAssertion( "peptide O-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.26"^^xsd:string) "UDP-D-xylose:core protein beta-D-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.26"^^xsd:string) "UDP-D-xylose:protein beta-D-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein xylosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "receptor signaling complex scaffold activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Functions to provide a physical support for the assembly of a multiprotein receptor signaling complex."^^xsd:string) AnnotationAssertion( "receptor signalling complex scaffold activity"^^xsd:string) AnnotationAssertion( "receptor signaling complex scaffold protein activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10506216"^^xsd:string) "Functions as a physical support bridging the N-methyl-D-aspartate receptor-PSD-95-GKAP complex and the mGluR-Homer complex, which are involved in receptor signaling in synapses."^^xsd:string) AnnotationAssertion( "GKAP/Homer scaffold protein"^^xsd:string) AnnotationAssertion( "postsynaptic density scaffold protein"^^xsd:string) AnnotationAssertion(rdfs:label "GKAP/Homer scaffold activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "Pfam:PF00595"^^xsd:string) "Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins."^^xsd:string) AnnotationAssertion(rdfs:label "PDZ domain binding"^^xsd:string) AnnotationAssertion( "GLGF-domain binding"^^xsd:string) AnnotationAssertion( "DHR-domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "LDL binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a low-density lipoprotein particle, a lipoprotein particle that is rich in cholesterol esters and low in triglycerides, is typically composed of APOB100 and APOE, and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm."^^xsd:string) AnnotationAssertion(rdfs:label "low-density lipoprotein particle binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6."^^xsd:string) AnnotationAssertion(rdfs:label "pyridoxal phosphate binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "voltage gated proton channel activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:10615049"^^xsd:string) "Catalysis of the transmembrane transfer of a proton by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion(rdfs:label "voltage-gated proton channel activity"^^xsd:string) AnnotationAssertion( "voltage-dependent proton channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0815316194"^^xsd:string) "Interacting selectively and non-covalently with troponin C, the calcium-binding subunit of the troponin complex."^^xsd:string) AnnotationAssertion(rdfs:label "troponin C binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Enables the directed movement of nitric oxide, nitrogen monoxide, from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "nitric oxide transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.66"^^xsd:string) "formamide dehydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyanide hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.66"^^xsd:string) "formamide hydro-lyase (cyanide-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.66"^^xsd:string) "formamide hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.66"^^xsd:string) Annotation( "RHEA:21723"^^xsd:string) "Catalysis of the reaction: formamide = H(2)O + hydrogen cyanide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "extracellular matrix constituent, lubricant activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Functions as a lubricant for an extracellular matrix, such as a mucous membrane."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "semaphorin receptor binding"^^xsd:string) AnnotationAssertion( "semaphorin receptor ligand"^^xsd:string) AnnotationAssertion( "plexin ligand"^^xsd:string) AnnotationAssertion( "plexin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "PMID:12001990"^^xsd:string) "Interacting selectively and non-covalently with semaphorin receptors."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "apolipoprotein receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Combining with an apolipoprotein to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "lipoprotein receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) "plasma lipoprotein particle receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "lipoprotein particle receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:6495"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12827279"^^xsd:string) "Combining with a lipoprotein particle and delivering the lipoprotein particle into the cell via endocytosis. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "very-low-density lipoprotein particle receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Combining with a very-low-density lipoprotein particle and delivering the very-low-density lipoprotein into the cell via endocytosis."^^xsd:string) AnnotationAssertion( "VLDL receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "apolipoprotein E receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "very-low-density lipoprotein receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11226231"^^xsd:string) "Catalyzes transport of all four deoxy (d) NDPs, and, less efficiently, the corresponding dNTPs, in exchange for dNDPs, ADP, or ATP."^^xsd:string) AnnotationAssertion(rdfs:label "deoxynucleotide transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "enzyme modulator"^^xsd:string) AnnotationAssertion(rdfs:label "enzyme regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "catalytic regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Binds to and modulates the activity of an enzyme."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "nitric-oxide synthase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Modulates the activity of nitric oxide synthase."^^xsd:string) AnnotationAssertion( "nitric oxide synthase regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:16646"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates."^^xsd:string) AnnotationAssertion(rdfs:label "carbohydrate binding"^^xsd:string) AnnotationAssertion( "sugar binding"^^xsd:string) AnnotationAssertion( "selectin"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:18154"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with any polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically."^^xsd:string) AnnotationAssertion(rdfs:label "polysaccharide binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with cellulose."^^xsd:string) AnnotationAssertion(rdfs:label "cellulose binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "guanylate cyclase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Modulates the activity of guanylate cyclase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Increases the activity of guanylate cyclase."^^xsd:string) AnnotationAssertion( "guanylin"^^xsd:string) AnnotationAssertion(rdfs:label "guanylate cyclase activator activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stops, prevents or reduces the activity of guanylate cyclase."^^xsd:string) AnnotationAssertion(rdfs:label "guanylate cyclase inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "quinate 3-dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.24"^^xsd:string) "quinate:NAD(+) 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.24"^^xsd:string) "quinic dehydrogenase activity"^^xsd:string) AnnotationAssertion( "quinate:NAD 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.24"^^xsd:string) "Catalysis of the reaction: (-)-quinate + NAD+ = (-)-3-dehydroquinate + NADH + H+."^^xsd:string) AnnotationAssertion( "quinate:NAD(+) 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.24"^^xsd:string) "quinate:NAD 5-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glyoxylate reductase (NADP) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.79"^^xsd:string) "glyoxylate reductase (NADP+)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.79"^^xsd:string) "glycolate:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.79"^^xsd:string) "Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.79"^^xsd:string) "NADPH-glyoxylate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.99.9"^^xsd:string) "5,10-methylenetetrahydromethanopterin dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.9"^^xsd:string) "N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methylenetetrahydromethanopterin dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.9"^^xsd:string) Annotation( "RHEA:16724"^^xsd:string) "Catalysis of the reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 + 2 H(+) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.9"^^xsd:string) "5,10-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.86"^^xsd:string) "5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethanesulfonate 2-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.86"^^xsd:string) "N5-methyltetrahydromethanopterin--coenzyme M methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tetrahydromethanopterin S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.86"^^xsd:string) Annotation( "RHEA:17588"^^xsd:string) "Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme M = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M. 2-(methylthio)ethanesulfonate is also known as methyl-CoM."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.86"^^xsd:string) "tetrahydromethanopterin methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.86"^^xsd:string) "N(5)-methyltetrahydromethanopterin--coenzyme M methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.101"^^xsd:string) "FTR"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.101"^^xsd:string) "formylmethanofuran:5,6,7,8-tetrahydromethanopterin N5-formyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.101"^^xsd:string) "formylmethanofuran-tetrahydromethanopterin formyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.101"^^xsd:string) "formylmethanofuran:tetrahydromethanopterin formyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.101"^^xsd:string) "formylmethanofuran:5,6,7,8-tetrahydromethanopterin 5-formyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.101"^^xsd:string) Annotation( "RHEA:18064"^^xsd:string) "Catalysis of the reaction: 5,6,7,8-tetrahydromethanopterin + N-formylmethanofuran + H(+) = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + methanofuran."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.101"^^xsd:string) "N-formylmethanofuran(CHO-MFR):tetrahydromethanopterin(H4MPT) formyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.3.2"^^xsd:string) "5,10-methenyltetrahydrofolate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.2"^^xsd:string) "5-Formyltetrahydrofolate cyclodehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.2"^^xsd:string) Annotation( "RHEA:10491"^^xsd:string) "Catalysis of the reaction: 5-formyltetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + H(+) + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "5-formyltetrahydrofolate cyclo-ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.2"^^xsd:string) "formyltetrahydrofolic cyclodehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.2"^^xsd:string) "5-formyltetrahydrofolate cyclodehydrase"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.2"^^xsd:string) "methenyl-THF synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.2"^^xsd:string) "5-formyltetrahydrofolate cyclo-ligase (ADP-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "MCH receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with the cyclic peptide hormone melanin-concentrating hormone to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "melanin-concentrating hormone receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "Pfam:PF00412"^^xsd:string) "Interacting selectively and non-covalently with a LIM domain (for Lin-11 Isl-1 Mec-3) of a protein, a domain with seven conserved cysteine residues and a histidine, that binds two zinc ions and acts as an interface for protein-protein interactions."^^xsd:string) AnnotationAssertion(rdfs:label "LIM domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "Pfam:PF00560"^^xsd:string) "Interacting selectively and non-covalently with a LRR domain (leucine rich repeats) of a protein."^^xsd:string) AnnotationAssertion(rdfs:label "LRR domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles."^^xsd:string) AnnotationAssertion(rdfs:label "clathrin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "The action of a molecule that contributes to the structural integrity of an epidermal cutaneous structure."^^xsd:string) AnnotationAssertion(rdfs:label "structural constituent of epidermis"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "structural constituent of cutaneous appendage"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0878932437"^^xsd:string) "The action of a molecule that contributes to the structural integrity of cutaneous epidermal structures such as hairs, scales, or feathers."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.51"^^xsd:string) "3(or 17)beta-hydroxysteroid:NAD(P)+ oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.51"^^xsd:string) "3beta-hydroxysteroid dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.51"^^xsd:string) "3beta-hydroxy steroid dehydrogenase"^^xsd:string) AnnotationAssertion(rdfs:label "testosterone dehydrogenase [NAD(P)] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.51"^^xsd:string) "17beta-hydroxy steroid dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.51"^^xsd:string) "Catalysis of the reaction: testosterone + NAD(P)+ = androst-4-ene-3,17-dione + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.51"^^xsd:string) "beta-hydroxy steroid dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.51"^^xsd:string) "3(or 17)beta-hydroxysteroid dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "estrogen receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:17615392"^^xsd:string) "Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "saposin"^^xsd:string) AnnotationAssertion(rdfs:label "sphingolipid activator protein activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Any of a group of peptide cofactors of enzymes for the lysosomal degradation of sphingolipids. They stimulate various enzymes, including glucosylceramidase, galactosylceramidase, cerebroside-sulfatase, alpha-galactosidase, beta-galactosidase, and sphingomyelin phosphodiesterase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stops, prevents or reduces the activity of a protein serine/threonine kinase."^^xsd:string) AnnotationAssertion(rdfs:label "protein serine/threonine kinase inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stops, prevents or reduces the activity of a protein tyrosine kinase."^^xsd:string) AnnotationAssertion(rdfs:label "protein tyrosine kinase inhibitor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stops, prevents or reduces the activity of a transmembrane receptor protein tyrosine kinase."^^xsd:string) AnnotationAssertion(rdfs:label "transmembrane receptor protein tyrosine kinase inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stops, prevents or reduces the activity of a receptor signaling protein tyrosine kinase."^^xsd:string) AnnotationAssertion(rdfs:label "receptor signaling protein tyrosine kinase inhibitor activity"^^xsd:string) AnnotationAssertion( "receptor signalling protein tyrosine kinase inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Increases the activity of a protein kinase, an enzyme which phosphorylates a protein."^^xsd:string) AnnotationAssertion(rdfs:label "protein kinase activator activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Increases the activity of a protein tyrosine kinase, an enzyme which phosphorylates a tyrosyl phenolic group on a protein."^^xsd:string) AnnotationAssertion(rdfs:label "protein tyrosine kinase activator activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Increases the activity of a transmembrane receptor protein tyrosine kinase."^^xsd:string) AnnotationAssertion(rdfs:label "transmembrane receptor protein tyrosine kinase activator activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Increases the activity of a receptor signaling protein tyrosine kinase."^^xsd:string) AnnotationAssertion( "receptor signalling protein tyrosine kinase activator activity"^^xsd:string) AnnotationAssertion(rdfs:label "receptor signaling protein tyrosine kinase activator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "heparanase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10916150"^^xsd:string) "Catalysis of the cleavage of heparan sulfate; can degrade both heparan sulfate and heparin glycosaminoglycan chains."^^xsd:string) AnnotationAssertion( "heparinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ARF binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with ARF, ADP-ribosylation factor, a small monomeric cytosolic GTPase that, when bound to GTP, binds to the membranes of cells."^^xsd:string) AnnotationAssertion(rdfs:label "ADP-ribosylation factor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with an estrogen receptor."^^xsd:string) AnnotationAssertion(rdfs:label "estrogen receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis."^^xsd:string) AnnotationAssertion(rdfs:label "cyclin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:7903401"^^xsd:string) Annotation( "PMID:8087839"^^xsd:string) "An enzyme regulator activity that increases the processivity of polymerization by DNA polymerase, by allowing the polymerase to move rapidly along DNA while remaining topologically bound to it."^^xsd:string) AnnotationAssertion(rdfs:label "DNA polymerase processivity factor activity"^^xsd:string) AnnotationAssertion( "processivity clamp"^^xsd:string) AnnotationAssertion( "sliding clamp"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.18.2"^^xsd:string) "N-acetylneuraminic monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.2"^^xsd:string) "CMP-N-acetylneuraminate hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.2"^^xsd:string) "CMP-N-acetylneuraminate,ferrocytochrome-b5:oxygen oxidoreductase (N-acetyl-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.2"^^xsd:string) "cytidine monophosphoacetylneuraminate monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.2"^^xsd:string) "CMP-Neu5Ac hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.2"^^xsd:string) "cytidine-5'-monophosphate-N-acetylneuraminic acid hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "CMP-N-acetylneuraminate monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.18.2"^^xsd:string) "Catalysis of the reaction: CMP-N-acetylneuraminate + NADPH + H+ + O2 = CMP-N-glycoloylneuraminate + NADP+ + H2O."^^xsd:string) AnnotationAssertion( "CMP-N-acetylneuraminic acid hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.67"^^xsd:string) "long-chain-fatty-acyl-ethyl-ester acylhydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "fatty-acyl-ethyl-ester synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.67"^^xsd:string) "FAEE synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "fatty-acyl ethyl ester synthase "^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.67"^^xsd:string) "Catalysis of the reaction: a long-chain-acyl ethyl ester + H2O = a long-chain carboxylic acid + ethanol."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.67"^^xsd:string) "FAEES activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.2.1"^^xsd:string) "hyaluronidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.1"^^xsd:string) "mucinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.1"^^xsd:string) "spreading factor activity"^^xsd:string) AnnotationAssertion(rdfs:label "hyaluronate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.1"^^xsd:string) "glucuronoglycosaminoglycan lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.1"^^xsd:string) "Catalysis of the reaction: hyaluronate = n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.1"^^xsd:string) "hyaluronidase [but cf. EC 3.2.1.35 (hyalurononglucosaminidase) and EC 3.2.1.36 (hyaluronoglucuronidase)]"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "chondroitinase activity"^^xsd:string) AnnotationAssertion( "chondroitin lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "chondroitin AC lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.5"^^xsd:string) "Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups."^^xsd:string) AnnotationAssertion( "ChnAC"^^xsd:string) AnnotationAssertion( "chondroitinase AC"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.5"^^xsd:string) "chondroitin sulfate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.5"^^xsd:string) "chondroitin AC eliminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8506296"^^xsd:string) "1,25-(OH)2D3 24-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:17823"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "calcitriol 24-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8506296"^^xsd:string) "Catalysis of the hydroxylation of C-24 of 1-alpha,25-hydroxycholecalciferol (25-hydroxyvitamin D3; calcitriol)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0471331309"^^xsd:string) Annotation( "MetaCyc:RXN-9829"^^xsd:string) "Catalysis of the reaction: vitamin D3 + NADPH + H+ + O2 = calcidiol + NADP+ + H2O."^^xsd:string) AnnotationAssertion( "cholecalciferol 25-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "vitamin D3 25-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "structural constituent of tooth enamel"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "The action of a molecule that contributes to the structural integrity of tooth enamel."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the enzyme protein phosphatase 2B."^^xsd:string) AnnotationAssertion( "calcineurin binding"^^xsd:string) AnnotationAssertion(rdfs:label "protein phosphatase 2B binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "syntaxin-3 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the SNAP receptor syntaxin-3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:3198610"^^xsd:string) Annotation( "PMID:8710843"^^xsd:string) "Interacting selectively and non-covalently with the iron-responsive element, a regulatory sequence found in the 5'- and 3'-untranslated regions of mRNAs encoding many iron-binding proteins."^^xsd:string) AnnotationAssertion(rdfs:label "iron-responsive element binding"^^xsd:string) AnnotationAssertion( "IRE binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-1,4,5,6-tetrakisphosphate + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: inositol-1,4,5,6-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "FGFR antagonist activity"^^xsd:string) AnnotationAssertion( "FGF receptor antagonist activity"^^xsd:string) AnnotationAssertion(rdfs:label "fibroblast growth factor receptor antagonist activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacts with the fibroblast growth factor receptor to reduce the action of another ligand, the agonist."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:11416225"^^xsd:string) Annotation( "PMID:9792536"^^xsd:string) "The action characteristic of melanin-concentrating hormone, a cyclic peptide hormone that, upon receptor binding, induces melanin aggregation in melanocytes, and is also involved in regulating food intake and energy balance in mammals."^^xsd:string) AnnotationAssertion(rdfs:label "melanin-concentrating hormone activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "protein phosphatase type 2B, intrinsic regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Modulation of the activity of the enzyme protein phosphatase type 2B."^^xsd:string) AnnotationAssertion(rdfs:label "protein phosphatase type 2B regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Modulation of the activity of the enzyme protein phosphatase type 4."^^xsd:string) AnnotationAssertion( "protein phosphatase type 4, intrinsic regulator activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein phosphatase type 4 regulator activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Mo-molybdopterin synthase activity"^^xsd:string) AnnotationAssertion( "molybdopterin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8514783"^^xsd:string) "Catalysis of the conversion of precursor Z to molybdopterin, the final step in molybdopterin biosynthesis."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-17"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-17 receptor binding"^^xsd:string) AnnotationAssertion( "interleukin-17 receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-17 receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-17R"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-17 receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-17 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with any member of the interleukin-17 family of cytokines and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "ICAM-3 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "PMID:7515813"^^xsd:string) "Combining with ICAM-3, intercellular adhesion molecule 3, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. ICAM-3, or CD50, are constitutively expressed on monocytes, granulocytes and lymphocytes; on physiological stimulation, they become transiently phosphorylated on serine residues."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ICAM-3 receptor ligand"^^xsd:string) AnnotationAssertion( "intercellular adhesion molecule-3 receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "intercellular adhesion molecule-3 receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "PMID:11473836"^^xsd:string) "Interacting selectively and non-covalently with receptors for intercellular adhesion molecule-3 (ICAM-3), such as DC-SIGN and LFA-1."^^xsd:string) AnnotationAssertion( "ICAM-3 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:clt"^^xsd:string) "Antagonizes ribosome-mediated translation of mRNA into a polypeptide."^^xsd:string) AnnotationAssertion(rdfs:label "translation repressor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "high molecular weight B lymphocyte growth factor receptor binding"^^xsd:string) AnnotationAssertion( "high molecular weight B cell growth factor receptor ligand"^^xsd:string) AnnotationAssertion( "high molecular weight B-lymphocyte growth factor receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "high molecular weight B cell growth factor receptor binding"^^xsd:string) AnnotationAssertion( "high molecular weight B-cell growth factor receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the high molecular weight B cell growth factor receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:2681271"^^xsd:string) "HMW-BCGF receptor"^^xsd:string) AnnotationAssertion( "high molecular weight B-lymphocyte growth factor receptor activity"^^xsd:string) AnnotationAssertion( "high molecular weight B lymphocyte growth factor receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "high molecular weight B cell growth factor receptor activity"^^xsd:string) AnnotationAssertion( "high molecular weight B-cell growth factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:2681271"^^xsd:string) "Combining with a high molecular weight B cell growth factor and transmitting the signal to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "The function of a transcription cofactor that activates transcription in conjuction with a ligand-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself."^^xsd:string) AnnotationAssertion(rdfs:label "ligand-dependent nuclear receptor transcription coactivator activity"^^xsd:string) AnnotationAssertion( "ligand-dependent nuclear receptor transcription co-activator activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thyroid hormone receptor coactivator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "The function of a transcription cofactor that activates transcription in conjunction with a thyroid hormone-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself."^^xsd:string) AnnotationAssertion( "thyroid hormone receptor co-activator activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "urokinase plasminogen activator receptor activity"^^xsd:string) AnnotationAssertion( "urokinase plasminogen activator receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "U-plasminogen activator receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:16456079"^^xsd:string) "Combining with the urokinase plasminogen activator to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "uPAR"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kd"^^xsd:string) "Catalysis of the synthesis of free D-serine from L-serine."^^xsd:string) AnnotationAssertion(rdfs:label "serine racemase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "neurotensin receptor activity, non-G-protein coupled"^^xsd:string) AnnotationAssertion( "non-G-protein-coupled neurotensin receptor activity"^^xsd:string) AnnotationAssertion( "neurotensin receptor activity, non G protein coupled"^^xsd:string) AnnotationAssertion( "non G protein coupled neurotensin receptor activity"^^xsd:string) AnnotationAssertion( "non-G-protein coupled neurotensin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:9756851"^^xsd:string) "Combining with neurotensin, a neuropeptide active in the central and peripheral nervous system in mammals, and transmitting the signal from one side of the membrane to the other by a mechanism independent of coupling to G proteins."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-17E"^^xsd:string) AnnotationAssertion( "interleukin-17E receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-17E receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-17E receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:14769790"^^xsd:string) "Catalysis of the two-electron reduction of the disulfide of thioredoxins with electrons from ferredoxin involving a 4Fe-4S cluster and an adjacent active-site disulfide."^^xsd:string) AnnotationAssertion(rdfs:label "ferredoxin:thioredoxin reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fructosamine-3-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11016445"^^xsd:string) "Catalysis of the phosphorylation of fructosamine to form fructosamine-3-kinase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lactose binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:01928006X"^^xsd:string) "Interacting selectively and non-covalently with lactose, a disaccharide of glucose and galactose, the carbohydrate of milk."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.2.4"^^xsd:string) Annotation( "EC:2.1.2.5"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a formimino group from 5-formimidoyltetrahydrofolate to an acceptor molecule such as an amino acid."^^xsd:string) AnnotationAssertion( "formiminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "formimidoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glycine formiminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.4"^^xsd:string) "formiminoglycine formiminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.4"^^xsd:string) Annotation( "RHEA:24291"^^xsd:string) "Catalysis of the reaction: 5-formimidoyltetrahydrofolate + glycine = (6S)-5,6,7,8-tetrahydrofolate + N-formimidoylglycine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.4"^^xsd:string) "5-formimidoyltetrahydrofolate:glycine N-formimidoyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycine formimidoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.4"^^xsd:string) "FIG formiminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.2.5"^^xsd:string) "Catalysis of the reaction: 5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formimidoyl-L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.5"^^xsd:string) "glutamate formyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.5"^^xsd:string) "formiminoglutamic formiminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.5"^^xsd:string) "5-formimidoyltetrahydrofolate:L-glutamate N-formimidoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.5"^^xsd:string) "formiminoglutamic acid transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamate formimidoyltransferase activity"^^xsd:string) AnnotationAssertion( "glutamate formiminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nicotianamine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.43"^^xsd:string) Annotation( "RHEA:16484"^^xsd:string) "Catalysis of the reaction: 3 S-adenosyl-L-methionine(1+) = 3 S-methyl-5'-thioadenosine + 3 H(+) + nicotianamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.43"^^xsd:string) "S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-L-methionine 3-amino-3-carboxypropyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.94"^^xsd:string) Annotation( "RHEA:24399"^^xsd:string) "Catalysis of the reaction: scytalone = 1,3,8-trihydroxynaphthalene + H(2)O."^^xsd:string) AnnotationAssertion(rdfs:label "scytalone dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.94"^^xsd:string) "scytalone 7,8-hydro-lyase (1,3,8-trihydroxynaphthalene-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.94"^^xsd:string) "scytalone 7,8-hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.1.4"^^xsd:string) Annotation( "RHEA:22739"^^xsd:string) "Catalysis of the reaction: 5-formimidoyltetrahydrofolate + 2 H(+) = 5,10-methenyltetrahydrofolate + NH(4)(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.4"^^xsd:string) "5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing; 5,10-methenyltetrahydrofolate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.4"^^xsd:string) "formiminotetrahydrofolate cyclodeaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "formimidoyltetrahydrofolate cyclodeaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.4"^^xsd:string) "5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:7698645"^^xsd:string) "A small peptide excreted by a naturally transformable bacterium (e.g. Bacillus subtilis) that transmits a signal required for the establishment of competence."^^xsd:string) AnnotationAssertion(rdfs:label "competence pheromone activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "protease inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds."^^xsd:string) AnnotationAssertion(rdfs:label "peptidase inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "kynureninase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.3"^^xsd:string) "kynurenine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.3"^^xsd:string) "Catalysis of the reaction: L-kynurenine + H2O = anthranilate + L-alanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.3"^^xsd:string) "L-kynurenine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: 1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "inositol-4,5-bisphosphate 5-phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hemoglobin binding"^^xsd:string) AnnotationAssertion( "haemoglobin binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:35143"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin."^^xsd:string) AnnotationAssertion( "globin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inorganic diphosphate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "inorganic pyrophosphate transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11326272"^^xsd:string) "Catalysis of the transfer of inorganic diphosphate across a membrane."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins."^^xsd:string) AnnotationAssertion(rdfs:label "ankyrin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers."^^xsd:string) AnnotationAssertion(rdfs:label "spectrin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with small nucleolar RNA."^^xsd:string) AnnotationAssertion(rdfs:label "snoRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with any part of a small nucleolar ribonucleoprotein particle."^^xsd:string) AnnotationAssertion(rdfs:label "snoRNP binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dihydrolipoamide S-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.12"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: acyl-CoA + dihydrolipoamide = CoA + S-acyldihydrolipoamide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "The action of a molecule that contributes to the structural integrity of chromatin."^^xsd:string) AnnotationAssertion(rdfs:label "structural constituent of chromatin"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "triplet codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion( "tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mtg_MIT_16mar07"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "The codon binding activity of a tRNA that positions an activated amino acid, mediating its insertion at the correct point in the sequence of a nascent polypeptide chain during protein synthesis."^^xsd:string) AnnotationAssertion( "transfer RNA"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size."^^xsd:string) AnnotationAssertion(rdfs:label "Hsp70 protein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "receptor regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) "The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is changed."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) "The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased."^^xsd:string) AnnotationAssertion(rdfs:label "receptor activator activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "receptor inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) "The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is decreased."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed."^^xsd:string) AnnotationAssertion(rdfs:label "acetylcholine receptor regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "acetylcholine receptor activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is increased."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "acetylcholine receptor inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is decreased."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclic nucleotide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cAMP binding"^^xsd:string) AnnotationAssertion( "3',5'-cAMP binding"^^xsd:string) AnnotationAssertion( "3',5' cAMP binding"^^xsd:string) AnnotationAssertion( "cyclic AMP binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate)."^^xsd:string) AnnotationAssertion( "adenosine 3',5'-cyclophosphate binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3',5' cGMP binding"^^xsd:string) AnnotationAssertion( "cyclic GMP binding"^^xsd:string) AnnotationAssertion( "3',5'-cGMP binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate)."^^xsd:string) AnnotationAssertion(rdfs:label "cGMP binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with adenyl nucleotides, any compound consisting of adenosine esterified with (ortho)phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "adenyl nucleotide binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12457565"^^xsd:string) "Specifies the site of a posttranscriptional modification in an RNA molecule by base pairing with a short sequence around the target residue."^^xsd:string) AnnotationAssertion(rdfs:label "RNA modification guide activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "rRNA modification guide activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12457565"^^xsd:string) "Specifies the site of a posttranscriptional modification in an rRNA molecule by base pairing with a short sequence around the target residue."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12457565"^^xsd:string) "Specifies the site of a posttranscriptional modification in a tRNA molecule by base pairing with a short sequence around the target residue."^^xsd:string) AnnotationAssertion(rdfs:label "tRNA modification guide activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA pseudouridylation guide activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12457565"^^xsd:string) "Specifies the site of pseudouridylation in an RNA molecule by base pairing with a short sequence around the target residue."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "rRNA pseudouridylation guide activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12457565"^^xsd:string) "Specifies the site of pseudouridylation in an rRNA molecule by base pairing with a short sequence around the target residue."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tRNA pseudouridylation guide activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12457565"^^xsd:string) "Specifies the site of pseudouridylation in a tRNA molecule by base pairing with a short sequence around the target residue."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA 2'-O-ribose methylation guide activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12457565"^^xsd:string) "Specifies the site of 2'-O-ribose methylation in an RNA molecule by base pairing with a short sequence around the target residue."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "rRNA 2'-O-ribose methylation guide activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12457565"^^xsd:string) "Specifies the site of 2'-O-ribose methylation in an rRNA molecule by base pairing with a short sequence around the target residue."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "snRNA 2'-O-ribose methylation guide activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11733745"^^xsd:string) "Activity that provides specificity to a methylase by using base complementarity to guide site-specific 2'-O-ribose methylations to a small nuclear RNA molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12457565"^^xsd:string) "Specifies the site of 2'-O-ribose methylation in a tRNA molecule by base pairing with a short sequence around the target residue."^^xsd:string) AnnotationAssertion(rdfs:label "tRNA 2'-O-ribose methylation guide activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "snRNA pseudouridylation guide activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11733745"^^xsd:string) "Activity that provides specificity to a pseudouridine synthetase by using base complementarity to guide site-specific pseudouridylations to a small nuclear RNA molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "snRNA modification guide activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12457565"^^xsd:string) "Specifies the site of a posttranscriptional modification in an snRNA molecule by base pairing with a short sequence around the target residue."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.2.2"^^xsd:string) "PPase-N activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.2"^^xsd:string) "pectin trans-eliminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.2"^^xsd:string) "polygalacturonic acid trans-eliminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.2"^^xsd:string) "endopectin methyltranseliminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.2"^^xsd:string) "polygalacturonic acid lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.2"^^xsd:string) "endo-alpha-1,4-polygalacturonic acid lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.2"^^xsd:string) "polygalacturonate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.2"^^xsd:string) "polygalacturonic transeliminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.2"^^xsd:string) "Catalysis of the reaction: a pectate = a pectate + a pectate oligosaccharide with 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate end. This reaction is the eliminative cleavage of pectate to give oligosaccharides with 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.2"^^xsd:string) "endogalacturonate transeliminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.2"^^xsd:string) "PGA lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.2"^^xsd:string) "pectic acid transeliminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pectate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.2"^^xsd:string) "pectate transeliminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.2"^^xsd:string) "alpha-1,4-D-endopolygalacturonic acid lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.2"^^xsd:string) "(1->4)-alpha-D-galacturonan lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.2"^^xsd:string) "pectic lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.2"^^xsd:string) "pectic acid lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mb"^^xsd:string) "Catalysis of the reaction involving the transfer of a phosphatidate (otherwise known as diacylglycerol 3-phosphosphate) group."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "quinone cofactor methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mb"^^xsd:string) "Catalysis of the transfer of a methyl group from S-adenosylmethionine during the synthesis of quinone cofactors such as ubiquinone (coenzyme Q), menaquinone (vitamin K2), plastoquinone and phylloquinone (vitamin K1)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.38"^^xsd:string) "phosphopyruvate carboxykinase"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.38"^^xsd:string) "phosphoenolpyruvic carboxykinase (pyrophosphate)"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoenolpyruvate carboxykinase (diphosphate) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.38"^^xsd:string) "phosphoenolpyruvic carboxylase (pyrophosphate)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.38"^^xsd:string) "diphosphate:oxaloacetate carboxy-lyase (transphosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.38"^^xsd:string) "phosphoenolpyruvic carboxytransphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.38"^^xsd:string) "phosphoenolpyruvate carboxylase (pyrophosphate)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.38"^^xsd:string) "phosphopyruvate carboxylase (pyrophosphate)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.38"^^xsd:string) "diphosphate:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.38"^^xsd:string) "PEP carboxyphosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.38"^^xsd:string) "phosphoenolpyruvate carboxykinase (pyrophosphate) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.38"^^xsd:string) "phosphoenolpyruvate carboxyphosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.38"^^xsd:string) Annotation( "RHEA:22359"^^xsd:string) "Catalysis of the reaction: diphosphate + oxaloacetate = CO(2) + phosphate + phosphoenolpyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.38"^^xsd:string) "phosphoenolpyruvate carboxytransphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.38"^^xsd:string) "PEPCTrP"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.38"^^xsd:string) "phosphoenolpyruvic carboxykinase"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.38"^^xsd:string) "phosphopyruvate carboxykinase (pyrophosphate)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.16.1.8"^^xsd:string) "methionine synthase cob(II)alamin reductase (methylating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "[methionine synthase] reductase activity"^^xsd:string) AnnotationAssertion( "[methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing) activity"^^xsd:string) AnnotationAssertion( "5-methyltetrahydrofolate-homocysteine methyltransferase reductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.8"^^xsd:string) "methionine synthase-methylcob(I)alamin,S-adenosylhomocysteine:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.8"^^xsd:string) "methionine synthase reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.8"^^xsd:string) "methionine synthase-cobalamin methyltransferase (cob(II)alamin reducing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.8"^^xsd:string) "Catalysis of the reaction: [methionine synthase]-cob(II)alamin + NADPH + H+ + S-adenosyl methionine = [methionine synthase]-methylcob(I)alamin + S-adenosylhomocysteine + NADP+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11592983"^^xsd:string) "Catalysis of the transfer of the ADP-ribose group of NAD+ to the amino group at N2 of 2'-deoxyguanosine to yield N2-(alpha-ADP-ribos-1-yl)-2'-deoxyguanosine and its beta form."^^xsd:string) AnnotationAssertion(rdfs:label "NAD DNA ADP-ribosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "neurotransmitter receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-L-rhamnosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.40"^^xsd:string) "alpha-L-rhamnoside rhamnohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.40"^^xsd:string) "alpha-L-rhamnosidase T"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.40"^^xsd:string) "Catalysis of the hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.40"^^xsd:string) "alpha-L-rhamnosidase N"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of N-glycosidic bonds in an RNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "RNA glycosylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.22"^^xsd:string) "momorcochin-S"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.22"^^xsd:string) "ricin"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.22"^^xsd:string) "ribosomal ribonucleate N-glycosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.22"^^xsd:string) "rRNA N-glycohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.22"^^xsd:string) "gelonin"^^xsd:string) AnnotationAssertion(rdfs:label "rRNA N-glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.22"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of the N-glycosylic bond at A-4324 in 28S rRNA from rat ribosomes or corresponding sites in 28S RNA from other species."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.22"^^xsd:string) "RNA N-glycosidase activity"^^xsd:string) AnnotationAssertion( "rRNA N-glycosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.22"^^xsd:string) "saporins"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.22"^^xsd:string) "nigrin b"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.22"^^xsd:string) "mirabilis antiviral protein"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.11"^^xsd:string) "pectin methoxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.11"^^xsd:string) "pectase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.11"^^xsd:string) "pectinoesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.11"^^xsd:string) "pectin pectylhydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pectinesterase activity"^^xsd:string) AnnotationAssertion( "pectin methylesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.11"^^xsd:string) "pectin demethoxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.11"^^xsd:string) "Catalysis of the reaction: pectin + n H2O = n methanol + pectate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.11"^^xsd:string) "pectin methyl esterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.73"^^xsd:string) "hemicellulase accessory"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.73"^^xsd:string) "hydroxycinnamoyl esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.73"^^xsd:string) "cinnAE"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.73"^^xsd:string) "FAE-III"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.73"^^xsd:string) "FAEA"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.73"^^xsd:string) "FAE-I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.73"^^xsd:string) "ferulic acid esterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "feruloyl esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.73"^^xsd:string) "FAE-II"^^xsd:string) AnnotationAssertion( "cinnamoyl ester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.73"^^xsd:string) "Catalysis of the reaction: feruloyl-polysaccharide + H2O = ferulate + polysaccharide."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.73"^^xsd:string) "4-hydroxy-3-methoxycinnamoyl-sugar hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.7.1.1"^^xsd:string) "oxaloacetate acetylhydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oxaloacetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.1"^^xsd:string) Annotation( "RHEA:24435"^^xsd:string) "Catalysis of the reaction: H(2)O + oxaloacetate = acetate + H(+) + oxalate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.1"^^xsd:string) "oxalacetic hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.267"^^xsd:string) "2C-methyl-D-erythritol-4-phosphate (MEP) synthase activity"^^xsd:string) AnnotationAssertion( "DOXP reductoisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.267"^^xsd:string) "1-deoxy-D-xylulose-5-phosphate isomeroreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.267"^^xsd:string) Annotation( "RHEA:13720"^^xsd:string) "Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.267"^^xsd:string) "1-deoxyxylulose-5-phosphate reductoisomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-deoxy-D-xylulose-5-phosphate reductoisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.267"^^xsd:string) "2-C-methyl-D-erythritol-4-phosphate:NADP+ oxidoreductase (isomerizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.267"^^xsd:string) "DXP-reductoisomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the interconversion of arsenate and arsenite."^^xsd:string) AnnotationAssertion(rdfs:label "arsenate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arsenate reductase (thioredoxin) activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10737"^^xsd:string) "Catalysis of the reaction: arsenate + thioredoxin = arsenite + thioredoxin disulfide. Thioredoxin disulfide is also known as oxidized thioredoxin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on phosphorus or arsenic in donors"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a disulfide."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on phosphorus or arsenic in donors, with disulphide as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "transforming growth factor beta receptor, common-partner cytoplasmic mediator activity"^^xsd:string) AnnotationAssertion( "TGF-beta receptor, common-partner cytoplasmic mediator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "A TGF-beta cytoplasmic mediator that forms a complex with a phosphorylated pathway-specific mediator. The heterocomplex translocates to the nucleus to regulate transcription."^^xsd:string) AnnotationAssertion( "TGFbeta receptor, common-partner cytoplasmic mediator activity"^^xsd:string) AnnotationAssertion( "common-partner SMAD protein"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "inhibitory SMAD protein"^^xsd:string) AnnotationAssertion( "TGF-beta receptor, inhibitory cytoplasmic mediator activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9759503"^^xsd:string) "A TGF-beta cytoplasmic mediator that inhibits the signaling function of common-partner and pathway-specific mediators."^^xsd:string) AnnotationAssertion(rdfs:label "transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity"^^xsd:string) AnnotationAssertion( "TGFbeta receptor, inhibitory cytoplasmic mediator activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "A TGF-beta cytoplasmic mediator that is phosphorylated by a TGFbeta receptor and complexes with a common-partner mediator. The- heterocomplex translocates to the nucleus to regulate transcription."^^xsd:string) AnnotationAssertion( "TGFbeta receptor, pathway-specific cytoplasmic mediator activity"^^xsd:string) AnnotationAssertion(rdfs:label "transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity"^^xsd:string) AnnotationAssertion( "pathway-specific SMAD protein"^^xsd:string) AnnotationAssertion( "TGF-beta receptor, pathway-specific cytoplasmic mediator activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the U1 small nuclear RNA (U1 snRNA)."^^xsd:string) AnnotationAssertion(rdfs:label "U1 snRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the U2 small nuclear RNA (U2 snRNA)."^^xsd:string) AnnotationAssertion(rdfs:label "U2 snRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "U4 snRNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the U4 small nuclear RNA (U4 snRNA)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the U4atac small nuclear RNA (U4atac snRNA)."^^xsd:string) AnnotationAssertion(rdfs:label "U4atac snRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the U5 small nuclear RNA (U5 snRNA)."^^xsd:string) AnnotationAssertion(rdfs:label "U5 snRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the U6atac small nuclear RNA (U6atac snRNA)."^^xsd:string) AnnotationAssertion(rdfs:label "U6atac snRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "U11 snRNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the U11 small nuclear RNA (U11 snRNA)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the U12 small nuclear RNA (U12 snRNA)."^^xsd:string) AnnotationAssertion(rdfs:label "U12 snRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "pre-mRNA 5' splice site binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the pre-mRNA 5' splice site sequence."^^xsd:string) AnnotationAssertion(rdfs:label "pre-mRNA 5'-splice site binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "pre-mRNA 3' splice site binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the pre-mRNA 3' splice site sequence."^^xsd:string) AnnotationAssertion(rdfs:label "pre-mRNA 3'-splice site binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the 3' end of the U6 small nuclear RNA (U6 snRNA)."^^xsd:string) AnnotationAssertion( "U6 snRNA 3' end binding"^^xsd:string) AnnotationAssertion(rdfs:label "U6 snRNA 3'-end binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "protein-protein adaptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way."^^xsd:string) AnnotationAssertion(rdfs:label "protein binding, bridging"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Increases the rate of GTP hydrolysis by a GTPase of the Rac family."^^xsd:string) AnnotationAssertion(rdfs:label "Rac GTPase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pg"^^xsd:string) "Rac GAP activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Rac guanyl-nucleotide exchange factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rac family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GTPase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Modulates the rate of GTP hydrolysis by a GTPase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:1555811337"^^xsd:string) "Catalysis of the transfer of a methyl group from a donor to the C5 atom of the uridine residue at position 54 in a tRNA molecule."^^xsd:string) AnnotationAssertion( "RUMT"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA (m5U54) methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.35"^^xsd:string) "tRNA uracil 5-methyltransferase activity"^^xsd:string) AnnotationAssertion( "tRNA (uracil-5-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "ISBN:1555811337"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing thymine at position U54 of a transfer RNA. This occurs in most Gram-negative bacteria, some archae, and eukaryotes."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.35"^^xsd:string) "tRNA:m(5)U54-methyltransferase activity"^^xsd:string) AnnotationAssertion( "S-adenosyl methionine-dependent tRNA (m5U54) methyltransferase activity"^^xsd:string) AnnotationAssertion( "RUMT"^^xsd:string) AnnotationAssertion(rdfs:label "S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.35"^^xsd:string) "transfer RNA uracil methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.35"^^xsd:string) "S-adenosyl-L-methionine:tRNA (uracil-5-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.35"^^xsd:string) "ribothymidyl synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.35"^^xsd:string) "tRNA:m5U54-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.35"^^xsd:string) "RUMT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.35"^^xsd:string) "transfer RNA uracil 5-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.35"^^xsd:string) "M5U-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "RUMT"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "ISBN:1555811337"^^xsd:string) "Catalysis of the transfer of a methyl group from 5,10-methylenetetrahydrofolate to the C5 atom of the uridine residue at position 54 in a tRNA molecule. This occurs in most Gram-positive bacteria and some Gram-negative bacteria."^^xsd:string) AnnotationAssertion(rdfs:label "5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.21.4.2"^^xsd:string) Annotation( "RHEA:12235"^^xsd:string) "Catalysis of the reaction: acetyl phosphate + H(2)O + NH(4)(+) + thioredoxin disulfide = glycine + H(+) + phosphate + thioredoxin."^^xsd:string) AnnotationAssertion(rdfs:label "glycine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.4.2"^^xsd:string) "acetyl-phosphate ammonia:thioredoxin disulfide oxidoreductase (glycine-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.37"^^xsd:string) "Catalysis of the reaction: NAD+ + [dinitrogen reductase] = nicotinamide + ADP-D-ribosyl-[dinitrogen reductase]."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.37"^^xsd:string) "NAD-azoferredoxin (ADPribose)transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.37"^^xsd:string) "NAD+:[dinitrogen reductase] (ADP-D-ribosyl)transferase activity"^^xsd:string) AnnotationAssertion( "NAD-dinitrogen-reductase ADP-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.37"^^xsd:string) "ADP-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.37"^^xsd:string) "NAD--azoferredoxin (ADP-ribose)transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.16"^^xsd:string) "acetoacetate:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.16"^^xsd:string) Annotation( "RHEA:16120"^^xsd:string) "Catalysis of the reaction: acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "acetoacetate-CoA ligase activity"^^xsd:string) AnnotationAssertion( "acetoacetyl-CoA synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.2"^^xsd:string) "guanidinoacetate transmethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.2"^^xsd:string) "S-adenosyl-L-methionine:N-guanidinoacetate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.2"^^xsd:string) "methionine-guanidinoacetic transmethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.2"^^xsd:string) Annotation( "RHEA:10659"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + guanidinoacetate = S-adenosyl-L-homocysteine + creatine + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "guanidinoacetate N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.2"^^xsd:string) "guanidoacetate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.2"^^xsd:string) "guanidinoacetate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.2"^^xsd:string) "GA methylpherase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.12"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + L-methionine = S-adenosyl-L-homocysteine + S-methyl-L-methionine."^^xsd:string) AnnotationAssertion(rdfs:label "methionine S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.12"^^xsd:string) "methionine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.12"^^xsd:string) "S-adenosyl methionine:methionine methyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.12"^^xsd:string) "S-adenosylmethionine transmethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.12"^^xsd:string) "S-adenosyl-L-methionine:L-methionine S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.12"^^xsd:string) "S-adenosylmethionine-methionine methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fatty acid O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.15"^^xsd:string) "fatty acid methyltransferase activity"^^xsd:string) AnnotationAssertion( "fatty-acid O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.15"^^xsd:string) "S-adenosyl-L-methionine:fatty-acid O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.15"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + a fatty acid = S-adenosyl-L-homocysteine + a fatty acid methyl ester."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.18"^^xsd:string) "acylpolysacharide 6-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.18"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + 1,4-N1-D-glucooligosaccharide = S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.18"^^xsd:string) "S-adenosyl-L-methionine:1,4-alpha-D-glucan 6-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "polysaccharide O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.18"^^xsd:string) "polysaccharide methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.22"^^xsd:string) Annotation( "RHEA:14208"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + carnosine = S-adenosyl-L-homocysteine + anserine + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.22"^^xsd:string) "S-adenosyl-L-methionine:carnosine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "carnosine N-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phenol O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.25"^^xsd:string) "PMT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.25"^^xsd:string) "S-adenosyl-L-methionine:phenol O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.25"^^xsd:string) Annotation( "RHEA:14812"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + phenol = S-adenosyl-L-homocysteine + anisole + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.26"^^xsd:string) "S-adenosyl-L-methionine:2-iodophenol O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "iodophenol O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.26"^^xsd:string) Annotation( "RHEA:14316"^^xsd:string) "Catalysis of the reaction: 2-iodophenol + S-adenosyl-L-methionine = 1-iodo-2-methoxybenzene + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.27"^^xsd:string) "DIB O-methyltransferase (3,5-diiodo-4-hydroxy-benzoic acid)"^^xsd:string) AnnotationAssertion(rdfs:label "tyramine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.27"^^xsd:string) "S-adenosyl-methionine:tyramine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.27"^^xsd:string) "tyramine methylpherase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.27"^^xsd:string) Annotation( "RHEA:14868"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + tyramine = N-methyltyramine + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.27"^^xsd:string) "S-adenosyl-L-methionine:tyramine N-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "O-demethylpuromycin O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.38"^^xsd:string) "O-demethylpuromycin methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.38"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + O-demethylpuromycin = S-adenosyl-L-homocysteine + puromycin."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.38"^^xsd:string) "S-adenosyl-L-methionine:O-demethylpuromycin O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.39"^^xsd:string) "S-adenosyl-L-methionine:1D-myo-inositol 3-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.39"^^xsd:string) "S-adenosylmethionine:myo-inositol 1-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.39"^^xsd:string) "myo-inositol 1-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.39"^^xsd:string) "S-adenosyl-L-methionine:myo-inositol 1-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.39"^^xsd:string) "myo-inositol 1-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.39"^^xsd:string) Annotation( "RHEA:18880"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-3-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "inositol 3-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.39"^^xsd:string) "inositol L-1-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.39"^^xsd:string) "myo-inositol 1-O-methyltransferase (name based on 1L-numbering system and not 1D-numbering)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.40"^^xsd:string) "myo-inositol 3-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.40"^^xsd:string) "inositol 3-O-methyltransferase (name based on 1L-numbering system and not 1D-numbering)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.40"^^xsd:string) "S-adenosyl-L-methionine:myo-inositol 3-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.40"^^xsd:string) "inositol 3-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol 1-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.40"^^xsd:string) "inositol D-1-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.40"^^xsd:string) "S-adenosylmethionine:myo-inositol 3-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.40"^^xsd:string) "S-adenosyl-L-methionine:1D-myo-inositol 1-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.40"^^xsd:string) Annotation( "RHEA:17568"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-1-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GTP-dependent protein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) using energy from the hydrolysis of GTP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.66"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing a single residue of 2'-O-methyladenosine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.66"^^xsd:string) "thiostrepton-resistance methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.66"^^xsd:string) "rRNA adenosine 2'-methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.66"^^xsd:string) "RNA-pentose methylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "rRNA (adenosine-2'-O-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.66"^^xsd:string) "ribosomal ribonucleate adenosine 2'-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.66"^^xsd:string) "S-adenosyl-L-methionine:rRNA (adenosine-2'-O)-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.42"^^xsd:string) "o-dihydric phenol meta-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "luteolin O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.42"^^xsd:string) "luteolin 3'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.42"^^xsd:string) "o-diphenol m-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.42"^^xsd:string) "o-dihydric phenol methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.42"^^xsd:string) "luteolin methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.42"^^xsd:string) "S-adenosylmethionine:flavone/flavonol 3'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.42"^^xsd:string) "S-adenosyl-L-methionine:5,7,3',4'-tetrahydroxyflavone 3'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.42"^^xsd:string) Annotation( "RHEA:14592"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + luteolin = 4',5,7-trihydroxy-3'-methoxyflavone + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.44"^^xsd:string) "S-adenosyl-L-methionine:alpha-N,alpha-N-dimethyl-L-histidine alpha-N-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dimethylhistidine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.44"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha,N-alpha-dimethyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.44"^^xsd:string) "histidine-alpha-N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.44"^^xsd:string) "dimethylhistidine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.44"^^xsd:string) "S-adenosyl-L-methionine:Nalpha,Nalpha-dimethyl-L-histidine nalpha-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.46"^^xsd:string) "4'-hydroxyisoflavone methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.46"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + isoflavone = S-adenosyl-L-homocysteine + 4'-O-methylisoflavone."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.46"^^xsd:string) "isoflavone methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "isoflavone 4'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.46"^^xsd:string) "isoflavone O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.46"^^xsd:string) "S-adenosyl-L-methionine:isoflavone 4'-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.47"^^xsd:string) "indolepyruvate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.47"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + (indol-3-yl)pyruvate = S-adenosyl-L-homocysteine + (S)-3-(indol-3-yl)-2-oxobutanoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.47"^^xsd:string) "indolepyruvic acid methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "indolepyruvate C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.47"^^xsd:string) "indolepyruvate 3-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.47"^^xsd:string) "S-adenosyl-L-methionine:(indol-3-yl)pyruvate C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.47"^^xsd:string) "S-adenosyl-L-methionine:indolepyruvate C-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.49"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + a methylated amine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.49"^^xsd:string) "tryptamine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.49"^^xsd:string) "S-adenosyl-L-methionine:amine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.49"^^xsd:string) "tryptamine methyltransferase"^^xsd:string) AnnotationAssertion(rdfs:label "amine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.49"^^xsd:string) "arylamine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.49"^^xsd:string) "nicotine N-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.50"^^xsd:string) "loganate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.50"^^xsd:string) "S-adenosyl-L-methionine:loganate 11-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.50"^^xsd:string) "S-adenosyl-L-methionine:loganic acid methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "loganate O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.50"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + loganate = S-adenosyl-L-homocysteine + loganin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.53"^^xsd:string) "S-adenosyl-L-methionine:putrescine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.53"^^xsd:string) Annotation( "RHEA:15040"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + putrescine = N-methylputrescine + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "putrescine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.53"^^xsd:string) "putrescine methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "licodione 2'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.65"^^xsd:string) "S-adenosyl-L-methionine:licodione 2'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.65"^^xsd:string) Annotation( "RHEA:18524"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + licodione = 2'-O-methyllicodione + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.69"^^xsd:string) "bergaptol methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.69"^^xsd:string) "S-adenosyl-L-methionine:5-hydroxyfuranocoumarin 5-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.69"^^xsd:string) "S-adenosyl-L-methionine:bergaptol O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.69"^^xsd:string) "BMT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.69"^^xsd:string) "S-adenosyl-L-methionine:5-hydroxyfurocoumarin 5-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.69"^^xsd:string) "furanocoumarin 5-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.69"^^xsd:string) "S-adenosyl-L-methionine:bergaptolO-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.69"^^xsd:string) "furanocoumarin 5-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.69"^^xsd:string) "bergaptol O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "5-hydroxyfuranocoumarin 5-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.69"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + 5-hydroxyfuranocoumarin = S-adenosyl-L-homocysteine + 5-methoxyfuranocoumarin."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.69"^^xsd:string) "bergaptol 5-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.70"^^xsd:string) "S-adenosyl-L-methionine:xanthotoxol O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.70"^^xsd:string) "furanocoumarin 8-O-methyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.70"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + xanthotoxol = S-adenosyl-L-homocysteine + xanthotoxin. Xanthotoxol is also known as 8-hydroxyfuranocoumarin and xanthotoxin as 8-methoxyfuranocoumarin."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.70"^^xsd:string) "furanocoumarin 8-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.70"^^xsd:string) "S-adenosyl-L-methionine:8-hydroxyfuranocoumarin 8-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.70"^^xsd:string) "XMT activity"^^xsd:string) AnnotationAssertion(rdfs:label "8-hydroxyfuranocoumarin 8-O-methyltransferase activity"^^xsd:string) AnnotationAssertion( "xanthotoxol O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.70"^^xsd:string) "xanthotoxol 8-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.70"^^xsd:string) "S-adenosyl-L-methionine:8-hydroxyfurocoumarin 8-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.70"^^xsd:string) "xanthotoxol methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.75"^^xsd:string) "S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone 4'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.75"^^xsd:string) "flavonoid O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "apigenin 4'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.75"^^xsd:string) "flavonoid methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.75"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone = S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.76"^^xsd:string) "flavonoid 3-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.76"^^xsd:string) "S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.76"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxy-flavone."^^xsd:string) AnnotationAssertion(rdfs:label "quercetin 3-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.76"^^xsd:string) "flavonol 3-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.78"^^xsd:string) "S-adenosyl-L-methionine:isoorientin 3'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.78"^^xsd:string) Annotation( "RHEA:24099"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + isoorientin = S-adenosyl-L-homocysteine + H(+) + isoscoparin."^^xsd:string) AnnotationAssertion(rdfs:label "isoorientin 3'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.78"^^xsd:string) "isoorientin 3'-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.82"^^xsd:string) "flavonol 7-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.82"^^xsd:string) Annotation( "RHEA:16184"^^xsd:string) "Catalysis of the reaction: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.82"^^xsd:string) "flavonol 7-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-methylquercitin 7-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.82"^^xsd:string) "3-methylquercetin 7-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.82"^^xsd:string) "S-adenosyl-L-methionine:5,7,3',4'-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.82"^^xsd:string) "7-OMT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.82"^^xsd:string) "S-adenosyl-L-methionine:3',4',5,7-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.83"^^xsd:string) Annotation( "RHEA:21835"^^xsd:string) "Catalysis of the reaction: 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',5-dihydroxy-3,4',7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.83"^^xsd:string) "flavonol 4'-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.83"^^xsd:string) "S-adenosyl-L-methionine:3',4',5-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3,7-dimethylquercitin 4'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.83"^^xsd:string) "4'-OMT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.83"^^xsd:string) "S-adenosyl-L-methionine:5,3',4'-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.83"^^xsd:string) "3,7-dimethylquercetin 4'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.83"^^xsd:string) "flavonol 4'-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.84"^^xsd:string) "S-adenosyl-L-methionine:3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone 6-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methylquercetagetin 6-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.84"^^xsd:string) "flavonol 6-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.84"^^xsd:string) Annotation( "RHEA:18720"^^xsd:string) "Catalysis of the reaction: 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,6,7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.84"^^xsd:string) "flavonol 6-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.84"^^xsd:string) "6-OMT"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyridine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.87"^^xsd:string) "pyridine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.87"^^xsd:string) "S-adenosyl-L-methionine:pyridine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.87"^^xsd:string) Annotation( "RHEA:16896"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + pyridine = N-methylpyridinium + S-adenosyl-L-homocysteine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.88"^^xsd:string) "flavonol 8-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.88"^^xsd:string) Annotation( "RHEA:16596"^^xsd:string) "Catalysis of the reaction: 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine(1+) = 3,3',4',5,7-pentahydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.88"^^xsd:string) "S-adenosyl-L-methionine:3,3',4',5,7,8-hexahydroxyflavone 8-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "8-hydroxyquercitin 8-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.88"^^xsd:string) "flavonol 8-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.88"^^xsd:string) "8-hydroxyquercetin 8-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.89"^^xsd:string) "tetrahydrocolumbamine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.89"^^xsd:string) Annotation( "RHEA:22539"^^xsd:string) "Catalysis of the reaction: (S)-tetrahydrocolumbamine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + H(+) + tetrahydropalmatine."^^xsd:string) AnnotationAssertion(rdfs:label "tetrahydrocolumbamine 2-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.89"^^xsd:string) "S-adenosyl-L-methionine:5,8,13,13a-tetrahydrocolumbamine 2-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "isobutyraldoxime O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.91"^^xsd:string) "S-adenosyl-L-methionine:2-methylpropanal-oxime O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.91"^^xsd:string) "aldoxime methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.91"^^xsd:string) "S-adenosylmethionine:aldoxime O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.91"^^xsd:string) "aldoxime O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.91"^^xsd:string) Annotation( "RHEA:10999"^^xsd:string) "Catalysis of the reaction: 2-methylpropanal oxime + S-adenosyl-L-methionine = 2-methylpropanal O-methyloxime + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.94"^^xsd:string) "11-demethyl-17-deacetylvindoline 11-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.94"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + 11-O-demethyl-17-O-deacetylvindoline = S-adenosyl-L-homocysteine + 17-O-deacetylvindoline."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.94"^^xsd:string) "tabersonine 16-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "11-O-demethyl-17-O-deacetylvindoline O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.94"^^xsd:string) "S-adenosyl-L-methionine:16-hydroxytabersonine 16-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.94"^^xsd:string) "S-adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline 11-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-hydroxyanthranilate 4-C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.97"^^xsd:string) Annotation( "RHEA:17836"^^xsd:string) "Catalysis of the reaction: 3-hydroxyanthranilate + S-adenosyl-L-methionine = 3-hydroxy-4-methylanthranilate + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.97"^^xsd:string) "S-adenosyl-L-methionine:3-hydroxyanthranilate 4-C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.97"^^xsd:string) "3-hydroxyanthranilate 4-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.99"^^xsd:string) "NMT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.99"^^xsd:string) "S-adenosyl-L-methionine:3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.99"^^xsd:string) Annotation( "RHEA:11339"^^xsd:string) "Catalysis of the reaction: (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + deacetoxyvindoline + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.99"^^xsd:string) "S-adenosyl-L-methionine:16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.99"^^xsd:string) "3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.99"^^xsd:string) "16-methoxy-2,3-dihydro-3-hydroxytabersonine methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.101"^^xsd:string) "S-adenosyl-L-methionine:macrocin 3'''-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "macrocin O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.101"^^xsd:string) "S-adenosyl-L-methionine-macrocin O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.101"^^xsd:string) "macrocin methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.101"^^xsd:string) Annotation( "RHEA:17272"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + macrocin = S-adenosyl-L-homocysteine + H(+) + tylosin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.102"^^xsd:string) "demethylmacrocin methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.102"^^xsd:string) Annotation( "RHEA:17576"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + demethylmacrocin = S-adenosyl-L-homocysteine + H(+) + macrocin."^^xsd:string) AnnotationAssertion(rdfs:label "demethylmacrocin O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.102"^^xsd:string) "S-adenosyl-L-methionine:demethylmacrocin 2'''-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.105"^^xsd:string) "S-adenosyl-L-methionine:N-benzoyl-4-O-hydroxyanthranilate 4-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.105"^^xsd:string) "benzoyl-CoA:anthranilate N-benzoyltransferase"^^xsd:string) AnnotationAssertion(rdfs:label "N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.105"^^xsd:string) Annotation( "RHEA:17408"^^xsd:string) "Catalysis of the reaction: N-benzoyl-4-hydroxyanthranilate + S-adenosyl-L-methionine(1+) = N-benzoyl-4-methoxyanthranilate + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.105"^^xsd:string) "N-benzoyl-4-hydroxyanthranilate 4-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.106"^^xsd:string) "S-adenosyl-L-methionine:L-tryptophan 2-C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.106"^^xsd:string) Annotation( "RHEA:17324"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + L-tryptophan = S-adenosyl-L-homocysteine + L-2-methyltryptophan + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "tryptophan 2-C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.106"^^xsd:string) "S-adenosylmethionine:tryptophan 2-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.106"^^xsd:string) "tryptophan 2-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "6-hydroxymellein O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.108"^^xsd:string) "6-hydroxymellein methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.108"^^xsd:string) "S-adenosyl-L-methionine:6-hydroxymellein 6-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.108"^^xsd:string) Annotation( "RHEA:15204"^^xsd:string) "Catalysis of the reaction: 6-hydroxymellein + S-adenosyl-L-methionine = 6-methoxymellein + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.111"^^xsd:string) "anthranilic acid N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.111"^^xsd:string) Annotation( "RHEA:12183"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + anthranilate = N-methylanthranilate + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.111"^^xsd:string) "S-adenosyl-L-methionine:anthranilate N-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "anthranilate N-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.112"^^xsd:string) "S-adenosyl-L-methionine:glucuronoxylan-D-glucuronate 4-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucuronoxylan 4-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.112"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + glucuronoxylan D-glucuronate = S-adenosyl-L-homocysteine + glucuronoxylan 4-O-methyl-D-glucuronate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.115"^^xsd:string) "(RS)-tetrahydrobenzylisoquinoline N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.115"^^xsd:string) "norreticuline N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.115"^^xsd:string) "S-adenosyl-L-methionine:(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.115"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline = S-adenosyl-L-homocysteine + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.117"^^xsd:string) "S-adenosyl-L-methionine:(S)-scoulerine 9-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.117"^^xsd:string) Annotation( "RHEA:23811"^^xsd:string) "Catalysis of the reaction: (S)-scoulerine + S-adenosyl-L-methionine(1+) = (S)-tetrahydrocolumbamine + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "(S)-scoulerine 9-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.117"^^xsd:string) "S-adenosyl-L-methionine:(S)-scoclaurine 9-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.118"^^xsd:string) Annotation( "RHEA:15376"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + columbamine = S-adenosyl-L-homocysteine + H(+) + palmatine."^^xsd:string) AnnotationAssertion(rdfs:label "columbamine O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.118"^^xsd:string) "S-adenosyl-L-methionine:columbamine O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.119"^^xsd:string) "S-adenosyl-L-methionine:10-hydroxydihydrosanguinarine 10-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.119"^^xsd:string) Annotation( "RHEA:18544"^^xsd:string) "Catalysis of the reaction: 10-hydroxydihydrosanguinarine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydrochelirubine + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "10-hydroxydihydrosanguinarine 10-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "12-hydroxydihydrochelirubine 12-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.120"^^xsd:string) Annotation( "RHEA:21095"^^xsd:string) "Catalysis of the reaction: 12-hydroxydihydrochelirubine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydromacarpine + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.120"^^xsd:string) "S-adenosyl-L-methionine:12-hydroxydihydrochelirubine 12-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "6-O-methylnorlaudanosoline 5'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.121"^^xsd:string) "S-adenosyl-L-methionine:6-O-methylnorlaudanosoline 5'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.121"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-homocysteine + nororientaline."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.122"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine = S-adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.122"^^xsd:string) "tetrahydroprotoberberine cis-N-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(S)-tetrahydroprotoberberine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.122"^^xsd:string) "S-adenosyl-L-methionine:(S)-7,8,13,14-tetrahydroprotoberberine cis-N-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "[cytochrome c]-methionine S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.123"^^xsd:string) "cytochrome c-methionine S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.123"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + [cytochrome c]-methionine = S-adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.123"^^xsd:string) "S-adenosyl-L-methionine:cytochrome c-methionine S-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.116"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine = S-adenosyl-L-homocysteine + (S)-reticuline."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.116"^^xsd:string) "S-adenosyl-L-methionine:3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.127"^^xsd:string) "S-adenosyl-L-methionine:3-phospho-D-glycerate-carboxy-lyase (dimerizing)-lysine 6-N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.127"^^xsd:string) "ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.127"^^xsd:string) "RuBisCO LSMT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.127"^^xsd:string) "ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit epsilonN-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.127"^^xsd:string) "ribulose-bisphosphate carboxylase-lysine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.127"^^xsd:string) "S-adenosyl-L-methionine:3-phospho-D-glycerate-carboxy-lyase (dimerizing)-lysine N6-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.127"^^xsd:string) "RuBisCO methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.127"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine = S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.128"^^xsd:string) "S-adenosyl-L-methionine:(RS)-norcoclaurine 6-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(RS)-norcoclaurine 6-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.128"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-norcoclaurine = S-adenosyl-L-homocysteine + (RS)-coclaurine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.129"^^xsd:string) "S-adenosyl-L-methionine:myo-inositol 4-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol 4-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.129"^^xsd:string) Annotation( "RHEA:23251"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-4-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.129"^^xsd:string) "S-adenosyl-L-methionine:1D-myo-inositol 4-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.129"^^xsd:string) "myo-inositol 6-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.129"^^xsd:string) "myo-inositol 4-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.130"^^xsd:string) "S-adenosyl-L-methionine--precorrin-2 methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.130"^^xsd:string) "S-adenosyl-L-methionine:precorrin-4 C20-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.130"^^xsd:string) Annotation( "RHEA:16844"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-2 = S-adenosyl-L-homocysteine + H(+) + precorrin-3A."^^xsd:string) AnnotationAssertion(rdfs:label "precorrin-2 C20-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.131"^^xsd:string) "precorrin-3 methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.131"^^xsd:string) "precorrin-3 methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.131"^^xsd:string) "CobJ"^^xsd:string) AnnotationAssertion(rdfs:label "precorrin-3B C17-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.131"^^xsd:string) "S-adenosyl-L-methionine:precorrin-3B C17-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.131"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-3B = S-adenosyl-L-homocysteine + precorrin 4."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.136"^^xsd:string) "trichlorophenol O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.136"^^xsd:string) "halogenated phenol O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.136"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + trichlorophenol = S-adenosyl-L-homocysteine + trichloroanisole."^^xsd:string) AnnotationAssertion(rdfs:label "chlorophenol O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.136"^^xsd:string) "S-adenosyl-L-methionine:trichlorophenol O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.137"^^xsd:string) "S-adenosyl-L-methionine:methylarsonite As-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.137"^^xsd:string) "S-adenosyl-L-methionine:arsenic(III) methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.137"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + arsenite = S-adenosyl-L-homocysteine + methylarsonate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.137"^^xsd:string) "S-adenosyl-L-methionine:arsenite As-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arsenite methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methylarsonite methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.138"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + methylarsonite = S-adenosyl-L-homocysteine + dimethylarsinate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.139"^^xsd:string) "S-adenosyl-L-methionine:3'-demethylstaurosporine O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.139"^^xsd:string) Annotation( "RHEA:11699"^^xsd:string) "Catalysis of the reaction: 3'-demethylstaurosporine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + H(+) + staurosporine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.139"^^xsd:string) "staurosporine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.139"^^xsd:string) "3'-demethoxy-3'-hydroxystaurosporine O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3'-demethylstaurosporine O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.140"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + (S)-coclaurine = S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.140"^^xsd:string) "S-adenosyl-L-methionine:(S)-coclaurine-N-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(S)-coclaurine-N-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.141"^^xsd:string) "jasmonic acid carboxyl methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "jasmonate O-methyltransferase activity"^^xsd:string) AnnotationAssertion( "S-adenosyl-L-methionine:jasmonic acid carboxyl methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.141"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + jasmonate = S-adenosyl-L-homocysteine + methyljasmonate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.141"^^xsd:string) "S-adenosyl-L-methionine:jasmonate O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.142"^^xsd:string) "sterol C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.142"^^xsd:string) Annotation( "RHEA:13140"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + cycloartenol = (24R)-24-methylcycloart-25-en-3beta-ol + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.142"^^xsd:string) "S-adenosyl-L-methionine:cycloartenol 24-C-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cycloartenol 24-C-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.143"^^xsd:string) "S-adenosyl-L-methionine:24-methylenelophenol C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.143"^^xsd:string) "24-methylenelophenol C-24(1)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.143"^^xsd:string) "SMT(2) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.143"^^xsd:string) "SMT2"^^xsd:string) AnnotationAssertion(rdfs:label "24-methylenesterol C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.143"^^xsd:string) Annotation( "RHEA:21047"^^xsd:string) "Catalysis of the reaction: 24-methylidenelophenol + S-adenosyl-L-methionine(1+) = (Z)-24-ethylidenelophenol + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.143"^^xsd:string) "24-methylenelophenol C-241-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.144"^^xsd:string) "S-adenosyl-L-methionine:(E)-prop-1-ene-1,2,3-tricarboxylate 2'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.144"^^xsd:string) Annotation( "RHEA:14972"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + trans-aconitate = (E)-3-(methoxycarbonyl)pent-2-enedioate + S-adenosyl-L-homocysteine."^^xsd:string) AnnotationAssertion(rdfs:label "trans-aconitate 2-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.1.16"^^xsd:string) "threo-3-hydroxy-L-aspartate ammonia-lyase (oxaloacetate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mcc"^^xsd:string) Annotation( "PMID:10481099"^^xsd:string) "3-hydroxyaspartate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.16"^^xsd:string) "threo-3-hydroxy-L-aspartate ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.16"^^xsd:string) "L-threo-3-hydroxyaspartate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.16"^^xsd:string) Annotation( "RHEA:12427"^^xsd:string) "Catalysis of the reaction: (3S)-3-hydroxy-L-aspartate = NH(4)(+) + oxaloacetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.16"^^xsd:string) "threo-3-hydroxyaspartate dehydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "threo-3-hydroxyaspartate ammonia-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-2-microglobulin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with beta-2-microglobulin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lipid antigen binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14500461"^^xsd:string) "Interacting selectively and non-covalently with a lipid antigen."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:14500461"^^xsd:string) "Interacting selectively and non-covalently with an endogenous cellular lipid antigen."^^xsd:string) AnnotationAssertion(rdfs:label "endogenous lipid antigen binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:14500461"^^xsd:string) "Interacting selectively and non-covalently with an exogenous lipid antigen (examples include microbial lipids and glycolipids)."^^xsd:string) AnnotationAssertion(rdfs:label "exogenous lipid antigen binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "actin-activated ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "actin-dependent ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of an actin filament to accelerate release of ADP and phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcium-dependent ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of calcium ion (Ca2+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a tetratricopeptide repeat (TPR) domain of a protein, the consensus sequence of which is defined by a pattern of small and large hydrophobic amino acids and a structure composed of helices."^^xsd:string) AnnotationAssertion(rdfs:label "TPR domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chloroplast targeting sequence binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a chloroplast targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the chloroplast."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ER signal peptide binding"^^xsd:string) AnnotationAssertion(rdfs:label "endoplasmic reticulum signal peptide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with an endoplasmic reticulum signal peptide, a specific peptide sequence that acts as a signal to localize the protein within the endoplasmic reticulum."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "mitochondrial targeting sequence binding"^^xsd:string) AnnotationAssertion(rdfs:label "mitochondrion targeting sequence binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a mitochondrion targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the mitochondrion."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DDEL sequence binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a KDEL sequence, the C terminus tetrapeptide sequence Asp-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein tyrosine phosphatase activity, via thiol-phosphate intermediate"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "The catalysis of phosphate removal from a phosphotyrosine using cysteine as a nucleophile and proceed by means of a thiol-phosphate intermediate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. This reaction requires metal ions."^^xsd:string) AnnotationAssertion(rdfs:label "protein tyrosine phosphatase activity, metal-dependent"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "potassium ion binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with potassium (K+) ions."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9094689"^^xsd:string) "Interacting selectively and non-covalently with Tat, a viral transactivating regulatory protein from the human immunodeficiency virus, or the equivalent protein from another virus."^^xsd:string) AnnotationAssertion(rdfs:label "Tat protein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a receptor that possesses protein tyrosine kinase activity."^^xsd:string) AnnotationAssertion(rdfs:label "receptor tyrosine kinase binding"^^xsd:string) AnnotationAssertion( "transmembrane receptor protein tyrosine kinase ligand binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Interacting selectively and non-covalently with molybdate (MoO4 2-) ions."^^xsd:string) AnnotationAssertion(rdfs:label "molybdate ion binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "thiamin binding"^^xsd:string) AnnotationAssertion( "vitamin B1 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Interacting selectively and non-covalently with thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver."^^xsd:string) AnnotationAssertion(rdfs:label "thiamine binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "aneurine pyrophosphate binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:45931"^^xsd:string) Annotation( "GOC:mlg"^^xsd:string) "Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases."^^xsd:string) AnnotationAssertion( "diphosphothiamin binding"^^xsd:string) AnnotationAssertion( "TPP binding"^^xsd:string) AnnotationAssertion(rdfs:label "thiamine pyrophosphate binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "thiamin pyrophosphate binding"^^xsd:string) AnnotationAssertion( "cocarboxylase binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "taurine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Interacting selectively and non-covalently with taurine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "mispair binding"^^xsd:string) AnnotationAssertion(rdfs:label "mismatched DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with double-stranded DNA containing one or more mismatches."^^xsd:string) AnnotationAssertion( "mispaired DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9520414"^^xsd:string) "Interacting selectively and non-covalently with a kininogen, any of a group of plasma proteins that are kinin precursors."^^xsd:string) AnnotationAssertion(rdfs:label "kininogen binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "HK binding"^^xsd:string) AnnotationAssertion( "HMW kininogen binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9520414"^^xsd:string) "Interacting selectively and non-covalently with a kininogen of high molecular mass."^^xsd:string) AnnotationAssertion(rdfs:label "high molecular weight kininogen binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9520414"^^xsd:string) "Interacting selectively and non-covalently with a kininogen of low molecular mass."^^xsd:string) AnnotationAssertion(rdfs:label "low molecular weight kininogen binding"^^xsd:string) AnnotationAssertion( "LK binding"^^xsd:string) AnnotationAssertion( "LMW kininogen binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "high molecular weight kininogen receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a high molecular weight kininogen receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:11336782"^^xsd:string) "Interacting selectively and non-covalently with a filamin, any member of a family of high molecular mass cytoskeletal proteins that crosslink actin filaments to form networks and stress fibers. Filamins contain an amino-terminal alpha-actinin-like actin binding domain, which is followed by a rod-domain composed of 4 to 24 100-residue repetitive segments including a carboxy-terminal dimerization domain."^^xsd:string) AnnotationAssertion( "filamin-B binding"^^xsd:string) AnnotationAssertion( "ABPL binding"^^xsd:string) AnnotationAssertion( "gamma-filamin binding"^^xsd:string) AnnotationAssertion( "filamin-A binding"^^xsd:string) AnnotationAssertion( "filamin A binding"^^xsd:string) AnnotationAssertion( "alpha-filamin binding"^^xsd:string) AnnotationAssertion( "filamin-C binding"^^xsd:string) AnnotationAssertion( "filamin-2 binding"^^xsd:string) AnnotationAssertion( "ABP-280 binding"^^xsd:string) AnnotationAssertion( "filamin B binding"^^xsd:string) AnnotationAssertion( "filamin C binding"^^xsd:string) AnnotationAssertion( "ABP-278/276 binding"^^xsd:string) AnnotationAssertion(rdfs:label "filamin binding"^^xsd:string) AnnotationAssertion( "filamin-3 binding"^^xsd:string) AnnotationAssertion( "filamin-1 binding"^^xsd:string) AnnotationAssertion( "beta-filamin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "troponin I binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0815316194"^^xsd:string) "Interacting selectively and non-covalently with troponin I, the inhibitory subunit of the troponin complex."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "troponin T binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0815316194"^^xsd:string) "Interacting selectively and non-covalently with troponin T, the tropomyosin-binding subunit of the troponin complex."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.1.7"^^xsd:string) "Catalysis of the reaction: L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.7"^^xsd:string) "IscS"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.7"^^xsd:string) "cysteine desulfurylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.7"^^xsd:string) "NIFS"^^xsd:string) AnnotationAssertion(rdfs:label "cysteine desulfurase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.7"^^xsd:string) "SufS"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.7"^^xsd:string) "L-cysteine:enzyme cysteine sulfurtransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock."^^xsd:string) AnnotationAssertion(rdfs:label "heat shock protein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cholesterol 26-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:950499"^^xsd:string) "Catalysis of the hydroxylation of cholesterol at position 26 of the side chain, to produce 26-hydroxycholesterol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.17"^^xsd:string) Annotation( "EC:3.5.1.98"^^xsd:string) Annotation( "RHEA:24551"^^xsd:string) "Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein."^^xsd:string) AnnotationAssertion(rdfs:label "histone deacetylase activity (H3-K14 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->2) linkage."^^xsd:string) AnnotationAssertion( "alpha-(1->2)-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-(1,2)-fucosyltransferase activity"^^xsd:string) AnnotationAssertion( "alpha-1,2-fucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "serine 3-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.276"^^xsd:string) "L-serine:NADP+ 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.276"^^xsd:string) Annotation( "RHEA:21599"^^xsd:string) "Catalysis of the reaction: L-serine + NADP(+) = L-alpha-formylglycine + 2 H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histone methylase activity (H3-K79 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone methyltransferase activity (H3-K79 specific)"^^xsd:string) AnnotationAssertion( "histone lysine N-methyltransferase activity (H3-K79 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:15371351"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 79) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 79). This reaction is the addition of a methyl group onto lysine at position 79 of the histone H3 protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ornithine N5-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11128"^^xsd:string) Annotation( "PMID:12828635"^^xsd:string) "Catalysis of the reaction: L-ornithine + O2 + H+ = N5-hydroxy-L-ornithine + H2O."^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11128"^^xsd:string) "L-ornithine 5-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.8"^^xsd:string) "1,4-beta-D-xylan xylanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.8"^^xsd:string) "1,4-beta-xylan xylanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.8"^^xsd:string) "endo-(1->4)-beta-xylanase(1->4)-beta-xylan 4-xylanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.8"^^xsd:string) "beta-1,4-xylanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.8"^^xsd:string) "endo-1,4-beta-D-xylanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.8"^^xsd:string) "endo-1,4-xylanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.8"^^xsd:string) "beta-D-xylanase activity"^^xsd:string) AnnotationAssertion(rdfs:label "endo-1,4-beta-xylanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.8"^^xsd:string) "beta-1,4-xylan xylanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.8"^^xsd:string) "xylanase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.8"^^xsd:string) "beta-xylanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.8"^^xsd:string) "Catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.8"^^xsd:string) "endo-(1,4)-beta-xylanase(1,4)-beta-xylan 4-xylanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.8"^^xsd:string) "endo-beta-1,4-xylanase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:16858"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with phosphopantetheine, the vitamin pantetheine 4'-(dihydrogen phosphate)."^^xsd:string) AnnotationAssertion(rdfs:label "phosphopantetheine binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "POZ domain binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:7958847"^^xsd:string) "Interacting selectively and non-covalently with a POZ (poxvirus and zinc finger) domain of a protein, a protein-protein interaction domain found in many transcription factors."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidylcholine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with phosphatidylcholine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of choline."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.135"^^xsd:string) "pullulan 4-D-glucanohydrolase (panose-forming)"^^xsd:string) AnnotationAssertion( "pullulanase II activity"^^xsd:string) AnnotationAssertion(rdfs:label "neopullulanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.135"^^xsd:string) Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the hydrolysis of pullulan to panose (6-alpha-D-glucosylmaltose)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "exo-beta-1,4-glucanase activity"^^xsd:string) AnnotationAssertion( "exocellulase activity"^^xsd:string) AnnotationAssertion( "exo-beta-1,4-glucosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucan 1,4-beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.74"^^xsd:string) "1,4-beta-D-glucan glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.74"^^xsd:string) "beta-1,4-beta-glucanase activity"^^xsd:string) AnnotationAssertion( "exo-1,4-beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.74"^^xsd:string) Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans, to remove successive glucose units."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.74"^^xsd:string) "exo-1,4-beta-D-glucosidase activity"^^xsd:string) AnnotationAssertion( "beta-1,4-glucanase activity"^^xsd:string) AnnotationAssertion( "exo-1,4-beta-glucanase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.89"^^xsd:string) Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in arabinogalactans."^^xsd:string) AnnotationAssertion( "arabinogalactanase activity"^^xsd:string) AnnotationAssertion( "galactanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.89"^^xsd:string) "arabinogalactan 4-beta-D-galactanohydrolase activity"^^xsd:string) AnnotationAssertion( "endo-1,4-beta-galactanase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arabinogalactan endo-1,4-beta-galactosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.65"^^xsd:string) Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the random hydrolysis of 2,6-beta-D-fructofuranosidic linkages in 2,6-beta-D-fructans (levans) containing more than 3 fructose units."^^xsd:string) AnnotationAssertion( "levan hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.65"^^xsd:string) "2,6-beta-D-fructan fructanohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "levanase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) Annotation( "PMID:10348846"^^xsd:string) "Catalysis of the reaction: maltodextrin = glucose-1-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "maltodextrin phosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Interacting selectively and non-covalently with denatured proteins."^^xsd:string) AnnotationAssertion(rdfs:label "denatured protein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the reaction: ATP + H2O + amine(out) = ADP + phosphate + amine(in)."^^xsd:string) AnnotationAssertion(rdfs:label "amine-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "amine ABC transporter"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a small monomeric GTPase."^^xsd:string) AnnotationAssertion(rdfs:label "small GTPase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:7522655"^^xsd:string) "Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,2-linkage."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-1,2-galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.77"^^xsd:string) "Tpa"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.77"^^xsd:string) "taurine:pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.77"^^xsd:string) Annotation( "RHEA:10423"^^xsd:string) "Catalysis of the reaction: pyruvate + taurine = L-alanine + sulfoacetaldehyde."^^xsd:string) AnnotationAssertion(rdfs:label "taurine-pyruvate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hexitol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: hexitol + acceptor = hexose + reduced acceptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "translation initiation factor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "eukaryotic initiation factor 4G binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with eukaryotic initiation factor 4G, a polypeptide factor involved in the initiation of ribosome-mediated translation."^^xsd:string) AnnotationAssertion( "eIF4G binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) "covalent modifier"^^xsd:string) AnnotationAssertion( "protein tagging activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein tag"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Acting as an indicator or marker to facilitate recognition by other molecules in the cell. Recognition of the tag, which can be covalently attached to the target molecule, may result in modification, sequestration, transport or degradation of the molecule in question."^^xsd:string) AnnotationAssertion( "ubiquitin"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with sodium ions (Na+)."^^xsd:string) AnnotationAssertion(rdfs:label "sodium ion binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lithium ion binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with lithium ions (Li+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "chloride binding"^^xsd:string) AnnotationAssertion(rdfs:label "chloride ion binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with chloride ions (Cl-)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with lipoic acid, 1,2-dithiolane-3-pentanoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "lipoic acid binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carboxylic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a carboxylic acid, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a pigment, any general or particular coloring matter in living organisms, e.g. melanin."^^xsd:string) AnnotationAssertion(rdfs:label "pigment binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-ascorbate binding"^^xsd:string) AnnotationAssertion(rdfs:label "L-ascorbic acid binding"^^xsd:string) AnnotationAssertion( "vitamin C binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:38290"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom."^^xsd:string) AnnotationAssertion( "vitamin B12 binding"^^xsd:string) AnnotationAssertion(rdfs:label "cobalamin binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with any alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen."^^xsd:string) AnnotationAssertion(rdfs:label "alkali metal ion binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12915569"^^xsd:string) "Interacting selectively and non-covalently with a hexon, the major protein component of the icosahedral capsid of an adenovirus."^^xsd:string) AnnotationAssertion(rdfs:label "hexon binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "titin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:10481174"^^xsd:string) "Interacting selectively and non-covalently with titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "telethonin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:10481174"^^xsd:string) "Interacting selectively and non-covalently with telethonin, a protein found in the Z disc of striated muscle and which is a substrate of the titin kinase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase, any protein that can phosphorylate a MAP kinase."^^xsd:string) AnnotationAssertion( "MAPKK binding"^^xsd:string) AnnotationAssertion(rdfs:label "mitogen-activated protein kinase kinase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mitogen-activated protein kinase kinase kinase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase."^^xsd:string) AnnotationAssertion( "MAPKKK binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "betaine ABC transporter"^^xsd:string) AnnotationAssertion(rdfs:label "betaine-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the reaction: ATP + H2O + a betaine(out) = ADP + phosphate + a betaine(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "N-trimethylglycine-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "glycine betaine ABC transporter"^^xsd:string) AnnotationAssertion(rdfs:label "glycine betaine-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the reaction: ATP + H2O + glycine betaine(out) = ADP + phosphate + glycine betaine(in)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "myosin III binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html"^^xsd:string) "Interacting selectively and non-covalently with a class III myosin; myosin III is monomeric and has an N terminal kinase domain."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "myosin V binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html"^^xsd:string) "Interacting selectively and non-covalently with a class V myosin; myosin V is a dimeric molecule involved in intracellular transport."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with DNA that is assembled into chromatin."^^xsd:string) AnnotationAssertion(rdfs:label "chromatin DNA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nucleosome binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the DNA portion of a nucleosome."^^xsd:string) AnnotationAssertion(rdfs:label "nucleosomal DNA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nucleosomal histone binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a histone that is assembled into a nucleosome."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:nln"^^xsd:string) "The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 730nm. The response may involve a change in conformation."^^xsd:string) AnnotationAssertion(rdfs:label "far-red light photoreceptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:nln"^^xsd:string) "The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660nm. The response may involve a change in conformation."^^xsd:string) AnnotationAssertion(rdfs:label "red light photoreceptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "gonadotropin-releasing hormone receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "gonadotrophin-releasing hormone receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pr"^^xsd:string) Annotation( "PMID:15196882"^^xsd:string) "Interacting selectively and non-covalently with a receptor for gonadotropin-releasing hormone (GnRH), a peptide hormone that is synthesized and released by the hypothalamus and is responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary."^^xsd:string) AnnotationAssertion( "GnRH receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "thyrotropin releasing hormone receptor binding"^^xsd:string) AnnotationAssertion( "thyrotropin-releasing hormone receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8592728"^^xsd:string) "Interacting selectively and non-covalently with a receptor for thyrotropin-releasing hormone, a tripeptide hormone that is produced by the hypothalamus and stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary."^^xsd:string) AnnotationAssertion(rdfs:label "thyrotropin-releasing hormone receptor binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peptidyl-proline dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl hydroxy-L-proline + succinate + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-3-hydroxy-L-proline + succinate + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "peptidyl-proline 3-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-4-hydroxy-L-proline + succinate + CO2."^^xsd:string) AnnotationAssertion( "HIF-type prolyl 4-hydroxylase"^^xsd:string) AnnotationAssertion( "prolyl 4-hydroxylase"^^xsd:string) AnnotationAssertion(rdfs:label "peptidyl-proline 4-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "brain-derived neurotrophic factor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the brain-derived neurotrophic factor receptor."^^xsd:string) AnnotationAssertion(rdfs:label "brain-derived neurotrophic factor receptor binding"^^xsd:string) AnnotationAssertion( "BDNF receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidosqualene cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "2,3-oxidosqualene cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ct"^^xsd:string) "Catalysis of the cyclization of (S)-2,3-epoxysqualene to form a triterpene."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a polymer of ubiqutin."^^xsd:string) AnnotationAssertion( "multiubiquitin binding"^^xsd:string) AnnotationAssertion(rdfs:label "polyubiquitin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ubiquitin conjugating enzyme binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vp"^^xsd:string) "Interacting selectively and non-covalently with a ubiquitin conjugating enzyme, any of the E2 proteins."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ubiquitin ligase binding"^^xsd:string) AnnotationAssertion(rdfs:label "ubiquitin protein ligase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vp"^^xsd:string) "Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:nln"^^xsd:string) Annotation( "PMID:6267560"^^xsd:string) "Interacting selectively and non-covalently with beta-endorphin, a peptide generated by the cleavage of pro-opiomelanocortin."^^xsd:string) AnnotationAssertion(rdfs:label "beta-endorphin binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "opioid receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an opioid receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "replication fork barrier binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with replication fork barriers, sites that inhibit the progress of replication forks."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NADH dehydrogenase (plastoquinone) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.6"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: NADH + H+ + plastoquinone = NAD+ + plastoquinol."^^xsd:string) AnnotationAssertion( "NADH:plastoquinone reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a G-protein beta subunit."^^xsd:string) AnnotationAssertion(rdfs:label "G-protein beta-subunit binding"^^xsd:string) AnnotationAssertion( "G-beta protein subunit binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "G-gamma protein subunit binding"^^xsd:string) AnnotationAssertion(rdfs:label "G-protein gamma-subunit binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a G-protein gamma subunit."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:nln"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with a complex of G-protein beta/gamma subunits."^^xsd:string) AnnotationAssertion(rdfs:label "G-protein beta/gamma-subunit complex binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "adenosine receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an adenosine receptor."^^xsd:string) AnnotationAssertion( "adenosine receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "A1 adenosine receptor binding"^^xsd:string) AnnotationAssertion( "A1 adenosine receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an A1 adenosine receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "A2A adenosine receptor binding"^^xsd:string) AnnotationAssertion( "A2A adenosine receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an A2A adenosine receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "A2B adenosine receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an A2B adenosine receptor."^^xsd:string) AnnotationAssertion(rdfs:label "A2B adenosine receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "A3 adenosine receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an A3 adenosine receptor."^^xsd:string) AnnotationAssertion(rdfs:label "A3 adenosine receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an adrenergic receptor."^^xsd:string) AnnotationAssertion( "adrenergic receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "adrenergic receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-1A adrenergic receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an alpha-1A adrenergic receptor."^^xsd:string) AnnotationAssertion( "alpha-1A adrenergic receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an alpha-1B adrenergic receptor."^^xsd:string) AnnotationAssertion( "alpha-1B adrenergic receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-1B adrenergic receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an alpha-1D adrenergic receptor."^^xsd:string) AnnotationAssertion( "alpha-1D adrenergic receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-1D adrenergic receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "alpha-2A adrenergic receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an alpha-2A adrenergic receptor."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-2A adrenergic receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "alpha-2B adrenergic receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-2B adrenergic receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an alpha-2B adrenergic receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an alpha-2C adrenergic receptor."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-2C adrenergic receptor binding"^^xsd:string) AnnotationAssertion( "alpha-2C adrenergic receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a beta-1 adrenergic receptor."^^xsd:string) AnnotationAssertion(rdfs:label "beta-1 adrenergic receptor binding"^^xsd:string) AnnotationAssertion( "beta-1 adrenergic receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-2 adrenergic receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a beta-2 adrenergic receptor."^^xsd:string) AnnotationAssertion( "beta-2 adrenergic receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-3 adrenergic receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a beta-3 adrenergic receptor."^^xsd:string) AnnotationAssertion( "beta-3 adrenergic receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "adrenomedullin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "adrenomedullin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an adrenomedullin receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "angiotensin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "angiotensin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an angiotensin receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 1 angiotensin receptor binding"^^xsd:string) AnnotationAssertion( "AT1 receptor binding"^^xsd:string) AnnotationAssertion( "type 1 angiotensin receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1 angiotensin receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "AT2 receptor binding"^^xsd:string) AnnotationAssertion( "type 2 angiotensin receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 2 angiotensin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 2 angiotensin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) Annotation( "GOC:vp"^^xsd:string) Annotation( "PMID:12787050"^^xsd:string) "Interacting selectively and non-covalently with an apelin receptor."^^xsd:string) AnnotationAssertion( "APJ receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "apelin receptor binding"^^xsd:string) AnnotationAssertion( "apelin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bombesin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a bombesin receptor."^^xsd:string) AnnotationAssertion( "bombesin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "subtype 3 bombesin receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a subtype 3 bombesin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "subtype 3 bombesin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "endothelin A receptor binding"^^xsd:string) AnnotationAssertion( "endothelin A receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an endothelin A receptor."^^xsd:string) AnnotationAssertion( "endothelin-1 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "endothelin B receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an endothelin B receptor."^^xsd:string) AnnotationAssertion( "endothelin B receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a gastrin-releasing peptide receptor."^^xsd:string) AnnotationAssertion( "gastrin-releasing peptide receptor ligand"^^xsd:string) AnnotationAssertion( "GRP receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "gastrin-releasing peptide receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a neuromedin B receptor."^^xsd:string) AnnotationAssertion(rdfs:label "neuromedin B receptor binding"^^xsd:string) AnnotationAssertion( "neuromedin B receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a bradykinin receptor."^^xsd:string) AnnotationAssertion( "bradykinin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "bradykinin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "B1 bradykinin receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a B1 bradykinin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "B1 bradykinin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a B2 bradykinin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "B2 bradykinin receptor binding"^^xsd:string) AnnotationAssertion( "B2 bradykinin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "C5a anaphylatoxin chemotactic receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a C5a anaphylatoxin chemotactic receptor."^^xsd:string) AnnotationAssertion(rdfs:label "C5a anaphylatoxin chemotactic receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "C5L2 anaphylatoxin chemotactic receptor binding"^^xsd:string) AnnotationAssertion( "C5L2 anaphylatoxin chemotactic receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a C5L2 anaphylatoxin chemotactic receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "calcitonin receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a calcitonin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "calcitonin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cannabinoid receptor binding"^^xsd:string) AnnotationAssertion( "cannabinoid receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a cannabinoid receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1 cannabinoid receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 1 cannabinoid receptor binding"^^xsd:string) AnnotationAssertion( "type 1 cannabinoid receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 2 cannabinoid receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 2 cannabinoid receptor binding"^^xsd:string) AnnotationAssertion( "type 2 cannabinoid receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "haptoglobin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a hemoglobin alpha chain."^^xsd:string) AnnotationAssertion(rdfs:label "hemoglobin alpha binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a hemoglobin beta chain."^^xsd:string) AnnotationAssertion(rdfs:label "hemoglobin beta binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "stromal cell-derived factor 1 receptor binding"^^xsd:string) AnnotationAssertion( "CXCR4 chemokine receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "CXCR4 chemokine receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a CXCR4 chemokine receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a CXCR5 chemokine receptor."^^xsd:string) AnnotationAssertion(rdfs:label "CXCR5 chemokine receptor binding"^^xsd:string) AnnotationAssertion( "type 1 Burkitt's lymphoma receptor binding"^^xsd:string) AnnotationAssertion( "CXCR5 chemokine receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CXCR6 chemokine receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a CXCR6 chemokine receptor."^^xsd:string) AnnotationAssertion( "CXCR6 chemokine receptor ligand"^^xsd:string) AnnotationAssertion( "STRL33 receptor binding"^^xsd:string) AnnotationAssertion( "bonzo receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "macrophage inflammatory protein-1 alpha receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a CCR1 chemokine receptor."^^xsd:string) AnnotationAssertion( "CCR1 chemokine receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "CCR1 chemokine receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a CCR2 chemokine receptor."^^xsd:string) AnnotationAssertion(rdfs:label "CCR2 chemokine receptor binding"^^xsd:string) AnnotationAssertion( "monocyte chemoattractant protein 1 receptor binding"^^xsd:string) AnnotationAssertion( "CCR2 chemokine receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "CCR3 chemokine receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "CCR3 chemokine receptor binding"^^xsd:string) AnnotationAssertion( "eosinophil eotaxin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a CCR3 chemokine receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "CCR4 chemokine receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "CCR4 chemokine receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a CCR4 chemokine receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CCR5 chemokine receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a CCR5 chemokine receptor."^^xsd:string) AnnotationAssertion( "CCR5 chemokine receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CCR6 chemokine receptor binding"^^xsd:string) AnnotationAssertion( "LARC receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a CCR6 chemokine receptor."^^xsd:string) AnnotationAssertion( "CCR6 chemokine receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CCR7 chemokine receptor binding"^^xsd:string) AnnotationAssertion( "type 1 EBV-induced G-protein coupled receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a CCR7 chemokine receptor."^^xsd:string) AnnotationAssertion( "CCR7 chemokine receptor ligand"^^xsd:string) AnnotationAssertion( "MIP-3 beta receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "CCR8 chemokine receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a CCR8 chemokine receptor."^^xsd:string) AnnotationAssertion(rdfs:label "CCR8 chemokine receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a CCR9 chemokine receptor."^^xsd:string) AnnotationAssertion( "CCR9 chemokine receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "CCR9 chemokine receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CCR10 chemokine receptor binding"^^xsd:string) AnnotationAssertion( "CCR10 chemokine receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a CCR10 chemokine receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CCR11 chemokine receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a CCR11 chemokine receptor."^^xsd:string) AnnotationAssertion( "CCR11 chemokine receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "CX3C chemokine receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a CX3C chemokine receptor."^^xsd:string) AnnotationAssertion( "fractalkine receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "CX3C chemokine receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a XCR1 chemokine receptor."^^xsd:string) AnnotationAssertion(rdfs:label "XCR1 chemokine receptor binding"^^xsd:string) AnnotationAssertion( "lymphotactin receptor binding"^^xsd:string) AnnotationAssertion( "XCR1 chemokine receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a cholecystokinin receptor."^^xsd:string) AnnotationAssertion( "cholecystokinin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "cholecystokinin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type A cholecystokinin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type A cholecystokinin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type A cholecystokinin receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type B gastrin/cholecystokinin receptor."^^xsd:string) AnnotationAssertion( "type B gastrin/cholecystokinin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type B gastrin/cholecystokinin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a cysteinyl leukotriene receptor."^^xsd:string) AnnotationAssertion(rdfs:label "cysteinyl leukotriene receptor binding"^^xsd:string) AnnotationAssertion( "cysteinyl leukotriene receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type 1 cysteinyl leukotriene receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1 cysteinyl leukotriene receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 1 cysteinyl leukotriene receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 2 cysteinyl leukotriene receptor."^^xsd:string) AnnotationAssertion( "type 2 cysteinyl leukotriene receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 2 cysteinyl leukotriene receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a D1 dopamine receptor."^^xsd:string) AnnotationAssertion(rdfs:label "D1 dopamine receptor binding"^^xsd:string) AnnotationAssertion( "D1 dopamine receptor ligand"^^xsd:string) AnnotationAssertion( "D1A dopamine receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "D2 dopamine receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "D2 dopamine receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a D2 dopamine receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "D3 dopamine receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a D3 dopamine receptor."^^xsd:string) AnnotationAssertion(rdfs:label "D3 dopamine receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "D4 dopamine receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a D4 dopamine receptor."^^xsd:string) AnnotationAssertion(rdfs:label "D4 dopamine receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D5 dopamine receptor binding"^^xsd:string) AnnotationAssertion( "D1B dopamine receptor binding"^^xsd:string) AnnotationAssertion( "D5 dopamine receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a D5 dopamine receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an endothelial differentiation G-protein coupled receptor."^^xsd:string) AnnotationAssertion( "endothelial differentiation G-protein coupled receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "endothelial differentiation G-protein coupled receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an Edg-1 sphingosine 1-phosphate receptor."^^xsd:string) AnnotationAssertion(rdfs:label "Edg-1 sphingosine 1-phosphate receptor binding"^^xsd:string) AnnotationAssertion( "Edg-1 sphingosine 1-phosphate receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an Edg-2 lysophosphatidic acid receptor."^^xsd:string) AnnotationAssertion( "Edg-2 lysophosphatidic acid receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "Edg-2 lysophosphatidic acid receptor binding"^^xsd:string) AnnotationAssertion( "LPA1 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an Edg-3 sphingosine 1-phosphate receptor."^^xsd:string) AnnotationAssertion( "Edg-3 sphingosine 1-phosphate receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "Edg-3 sphingosine 1-phosphate receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an Edg-4 lysophosphatidic acid receptor."^^xsd:string) AnnotationAssertion(rdfs:label "Edg-4 lysophosphatidic acid receptor binding"^^xsd:string) AnnotationAssertion( "LPA2 receptor binding"^^xsd:string) AnnotationAssertion( "Edg-4 lysophosphatidic acid receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an Edg-5 sphingosine 1-phosphate receptor."^^xsd:string) AnnotationAssertion( "Edg-5 sphingosine 1-phosphate receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "Edg-5 sphingosine 1-phosphate receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Edg-6 sphingosine 1-phosphate receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an Edg-6 sphingosine 1-phosphate receptor."^^xsd:string) AnnotationAssertion( "Edg-6 sphingosine 1-phosphate receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Edg-7 lysophosphatidic acid receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an Edg-7 lysophosphatidic acid receptor."^^xsd:string) AnnotationAssertion( "Edg-7 lysophosphatidic acid receptor ligand"^^xsd:string) AnnotationAssertion( "LPA3 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "fMet-Leu-Phe receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "fMet-Leu-Phe receptor binding"^^xsd:string) AnnotationAssertion( "N-formyl peptide receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a fMet-Leu-Phe receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "follicle-stimulating hormone receptor binding"^^xsd:string) AnnotationAssertion( "FSH receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a follicle-stimulating hormone receptor."^^xsd:string) AnnotationAssertion( "follicle stimulating hormone receptor binding"^^xsd:string) AnnotationAssertion( "follicle stimulating hormone receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "galanin receptor binding"^^xsd:string) AnnotationAssertion( "galanin receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a galanin receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 1 galanin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1 galanin receptor."^^xsd:string) AnnotationAssertion( "type 1 galanin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type 2 galanin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 2 galanin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 2 galanin receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 3 galanin receptor binding"^^xsd:string) AnnotationAssertion( "type 3 galanin receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 3 galanin receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "gastric inhibitory polypeptide receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "gastric inhibitory polypeptide receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a gastric inhibitory polypeptide receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a ghrelin receptor."^^xsd:string) AnnotationAssertion( "ghrelin receptor ligand"^^xsd:string) AnnotationAssertion( "type 1 growth hormone secretagogue GH-releasing peptide receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "ghrelin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glucagon receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a glucagon receptor."^^xsd:string) AnnotationAssertion(rdfs:label "glucagon receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a growth hormone-releasing hormone receptor."^^xsd:string) AnnotationAssertion(rdfs:label "growth hormone-releasing hormone receptor binding"^^xsd:string) AnnotationAssertion( "growth hormone-releasing hormone receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 1 hypocretin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1 hypocretin receptor."^^xsd:string) AnnotationAssertion( "type 1 hypocretin receptor ligand"^^xsd:string) AnnotationAssertion( "type 1 orexin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type 2 hypocretin receptor ligand"^^xsd:string) AnnotationAssertion( "type 2 orexin receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "type 2 hypocretin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 2 hypocretin receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "metastin receptor binding"^^xsd:string) AnnotationAssertion( "G-protein coupled receptor 54 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a kisspeptin receptor."^^xsd:string) AnnotationAssertion( "hypogonadotropin-1 receptor binding"^^xsd:string) AnnotationAssertion( "hOT7T175 receptor binding"^^xsd:string) AnnotationAssertion( "KiSS-1 receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "kisspeptin receptor binding"^^xsd:string) AnnotationAssertion( "kisspeptin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a leukotriene receptor."^^xsd:string) AnnotationAssertion( "leukotriene receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "leukotriene receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lutropin-choriogonadotropic hormone receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a lutropin-choriogonadotropic hormone receptor."^^xsd:string) AnnotationAssertion( "lutropin-choriogonadotropic hormone receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "melanin-concentrating hormone receptor binding"^^xsd:string) AnnotationAssertion( "melanin-concentrating hormone receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a melanin-concentrating hormone receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1 melanin-concentrating hormone receptor."^^xsd:string) AnnotationAssertion( "type 1 melanin-concentrating hormone receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 1 melanin-concentrating hormone receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type 2 melanin-concentrating hormone receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 2 melanin-concentrating hormone receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 2 melanin-concentrating hormone receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "melanocortin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "melanocortin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a melanocortin receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "corticotropin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "adrenocorticotropin hormone receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a corticotropin hormone receptor."^^xsd:string) AnnotationAssertion( "adrenocorticotropic hormone receptor ligand"^^xsd:string) AnnotationAssertion( "ACTH receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "corticotropin hormone receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "adrenocorticotropin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 3 melanocortin receptor."^^xsd:string) AnnotationAssertion( "type 3 melanocortin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 3 melanocortin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 4 melanocortin receptor."^^xsd:string) AnnotationAssertion( "type 4 melanocortin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 4 melanocortin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 5 melanocortin receptor."^^xsd:string) AnnotationAssertion( "type 5 melanocortin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 5 melanocortin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "melatonin receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a melatonin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "melatonin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1A melatonin receptor."^^xsd:string) AnnotationAssertion( "type 1A melatonin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 1A melatonin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 1B melatonin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1B melatonin receptor."^^xsd:string) AnnotationAssertion( "type 1B melatonin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "H9 melatonin receptor binding"^^xsd:string) AnnotationAssertion( "H9 melatonin receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a H9 melatonin receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a motilin receptor."^^xsd:string) AnnotationAssertion( "motilin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "motilin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "muscarinic acetylcholine receptor binding"^^xsd:string) AnnotationAssertion( "muscarinic acetylcholine receptor ligand"^^xsd:string) AnnotationAssertion( "M3 muscarinic acetylcholine receptor binding"^^xsd:string) AnnotationAssertion( "M1 muscarinic acetylcholine receptor binding"^^xsd:string) AnnotationAssertion( "M5 muscarinic acetylcholine receptor ligand"^^xsd:string) AnnotationAssertion( "M3 muscarinic acetylcholine receptor ligand"^^xsd:string) AnnotationAssertion( "M5 muscarinic acetylcholine receptor binding"^^xsd:string) AnnotationAssertion( "M2 muscarinic acetylcholine receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a G-protein coupled acetylcholine receptor."^^xsd:string) AnnotationAssertion( "M4 muscarinic acetylcholine receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled acetylcholine receptor binding"^^xsd:string) AnnotationAssertion( "M1 muscarinic acetylcholine receptor ligand"^^xsd:string) AnnotationAssertion( "M4 muscarinic acetylcholine receptor ligand"^^xsd:string) AnnotationAssertion( "M2 muscarinic acetylcholine receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "GABAB receptor binding"^^xsd:string) AnnotationAssertion( "metabotropic GABA receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "metabotropic GABA receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled GABA receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a G-protein coupled (metabotropic) GABA receptor."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1 metabotropic GABA receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 1 metabotropic GABA receptor binding"^^xsd:string) AnnotationAssertion( "type 1 metabotropic GABA receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 2 metabotropic GABA receptor binding"^^xsd:string) AnnotationAssertion( "type 2 metabotropic GABA receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 2 metabotropic GABA receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 1 metabotropic glutamate receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1 metabotropic glutamate receptor."^^xsd:string) AnnotationAssertion( "type 1 metabotropic glutamate receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type 2 metabotropic glutamate receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 2 metabotropic glutamate receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 2 metabotropic glutamate receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type 3 metabotropic glutamate receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 3 metabotropic glutamate receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 3 metabotropic glutamate receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 4 metabotropic glutamate receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 4 metabotropic glutamate receptor binding"^^xsd:string) AnnotationAssertion( "type 4 metabotropic glutamate receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 5 metabotropic glutamate receptor."^^xsd:string) AnnotationAssertion( "type 5 metabotropic glutamate receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 5 metabotropic glutamate receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 6 metabotropic glutamate receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 6 metabotropic glutamate receptor binding"^^xsd:string) AnnotationAssertion( "type 6 metabotropic glutamate receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 7 metabotropic glutamate receptor."^^xsd:string) AnnotationAssertion( "type 7 metabotropic glutamate receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 7 metabotropic glutamate receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type 8 metabotropic glutamate receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 8 metabotropic glutamate receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 8 metabotropic glutamate receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "metabotropic histamine receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) Annotation( "PMID:12679144"^^xsd:string) "Interacting selectively and non-covalently with a G-protein coupled (metabotropic) histamine receptor."^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled histamine receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "metabotropic histamine receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "H1 histamine receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a H1 histamine receptor."^^xsd:string) AnnotationAssertion(rdfs:label "H1 histamine receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a H2 histamine receptor."^^xsd:string) AnnotationAssertion(rdfs:label "H2 histamine receptor binding"^^xsd:string) AnnotationAssertion( "H2 histamine receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a H3 histamine receptor."^^xsd:string) AnnotationAssertion( "H3 histamine receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "H3 histamine receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "H4 histamine receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a H4 histamine receptor."^^xsd:string) AnnotationAssertion( "H4 histamine receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a G-protein coupled (metabotropic) nucleotide receptor."^^xsd:string) AnnotationAssertion( "P2Y receptor binding"^^xsd:string) AnnotationAssertion( "metabotropic nucleotide receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled nucleotide receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "metabotropic nucleotide receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a P2Y1 nucleotide receptor."^^xsd:string) AnnotationAssertion( "P2Y1 nucleotide receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "P2Y1 nucleotide receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "P2Y2 nucleotide receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a P2Y2 nucleotide receptor."^^xsd:string) AnnotationAssertion( "P2Y2 nucleotide receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a P2Y4 nucleotide receptor."^^xsd:string) AnnotationAssertion( "P2Y4 nucleotide receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "P2Y4 nucleotide receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "P2Y5 nucleotide receptor binding"^^xsd:string) AnnotationAssertion( "P2Y5 nucleotide receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a P2Y5 nucleotide receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a P2Y6 nucleotide receptor."^^xsd:string) AnnotationAssertion( "P2Y6 nucleotide receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "P2Y6 nucleotide receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "P2Y8 nucleotide receptor binding"^^xsd:string) AnnotationAssertion( "P2Y8 nucleotide receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a P2Y8 nucleotide receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a P2Y9 nucleotide receptor."^^xsd:string) AnnotationAssertion( "P2Y9 nucleotide receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "P2Y9 nucleotide receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "P2Y10 nucleotide receptor binding"^^xsd:string) AnnotationAssertion( "P2Y10 nucleotide receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a P2Y10 nucleotide receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a P2Y11 nucleotide receptor."^^xsd:string) AnnotationAssertion( "P2Y11 nucleotide receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "P2Y11 nucleotide receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "metabotropic serotonin receptor binding"^^xsd:string) AnnotationAssertion( "metabotropic 5-hydroxytryptamine receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a metabotropic serotonin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled serotonin receptor binding"^^xsd:string) AnnotationAssertion( "metabotropic serotonin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type 1B serotonin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 1B serotonin receptor binding"^^xsd:string) AnnotationAssertion( "5-hydroxytryptamine 1B receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1B serotonin receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "5-hydroxytryptamine 1D receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1D serotonin receptor."^^xsd:string) AnnotationAssertion( "type 1D serotonin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 1D serotonin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 1E serotonin receptor binding"^^xsd:string) AnnotationAssertion( "5-hydroxytryptamine 1E receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1E serotonin receptor."^^xsd:string) AnnotationAssertion( "type 1E serotonin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "5-hydroxytryptamine 1F receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1F serotonin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 1F serotonin receptor binding"^^xsd:string) AnnotationAssertion( "type 1F serotonin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "5-hydroxytryptamine 2A receptor binding"^^xsd:string) AnnotationAssertion( "type 2A serotonin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 2A serotonin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 2A serotonin receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type 2B serotonin receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 2B serotonin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 2B serotonin receptor binding"^^xsd:string) AnnotationAssertion( "5-hydroxytryptamine 2B receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 2C serotonin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 2C serotonin receptor binding"^^xsd:string) AnnotationAssertion( "type 2C serotonin receptor ligand"^^xsd:string) AnnotationAssertion( "5-hydroxytryptamine 2C receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 4 serotonin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 4 serotonin receptor."^^xsd:string) AnnotationAssertion( "type 4 serotonin receptor ligand"^^xsd:string) AnnotationAssertion( "5-hydroxytryptamine 4 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "5-hydroxytryptamine 5A receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 5A serotonin receptor."^^xsd:string) AnnotationAssertion( "type 5A serotonin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 5A serotonin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "5-hydroxytryptamine 5B receptor binding"^^xsd:string) AnnotationAssertion( "type 5B serotonin receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 5B serotonin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 5B serotonin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 6 serotonin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 6 serotonin receptor."^^xsd:string) AnnotationAssertion( "5-hydroxytryptamine 6 receptor binding"^^xsd:string) AnnotationAssertion( "type 6 serotonin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type 7 serotonin receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 7 serotonin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 7 serotonin receptor binding"^^xsd:string) AnnotationAssertion( "5-hydroxytryptamine 7 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a neurokinin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "neurokinin receptor binding"^^xsd:string) AnnotationAssertion( "neurokinin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "neurokinin-1 receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "substance P receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a substance P receptor."^^xsd:string) AnnotationAssertion( "substance P receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a neuromedin K receptor."^^xsd:string) AnnotationAssertion(rdfs:label "neuromedin K receptor binding"^^xsd:string) AnnotationAssertion( "neurokinin-B receptor binding"^^xsd:string) AnnotationAssertion( "neuromedin K receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a substance K receptor."^^xsd:string) AnnotationAssertion( "substance K receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "substance K receptor binding"^^xsd:string) AnnotationAssertion( "neurokinin-A receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type 1 neuromedin U receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 1 neuromedin U receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1 neuromedin U receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type 2 neuromedin U receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 2 neuromedin U receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 2 neuromedin U receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a neuropeptide Y receptor."^^xsd:string) AnnotationAssertion( "NPY receptor binding"^^xsd:string) AnnotationAssertion( "neuropeptide Y receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "neuropeptide Y receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type 1 neuropeptide Y receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 1 neuropeptide Y receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1 neuropeptide Y receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 2 neuropeptide Y receptor binding"^^xsd:string) AnnotationAssertion( "type 2 neuropeptide Y receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 2 neuropeptide Y receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type 4 neuropeptide Y receptor ligand"^^xsd:string) AnnotationAssertion( "pancreatic polypeptide receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 4 neuropeptide Y receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 4 neuropeptide Y receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 5 neuropeptide Y receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 5 neuropeptide Y receptor."^^xsd:string) AnnotationAssertion( "type 5 neuropeptide Y receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "neurotensin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "neurotensin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a neurotensin receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1 neurotensin receptor."^^xsd:string) AnnotationAssertion( "type 1 neurotensin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 1 neurotensin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "olfactory receptor binding"^^xsd:string) AnnotationAssertion( "olfactory receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an olfactory receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a delta-type opioid receptor."^^xsd:string) AnnotationAssertion( "delta-type opioid receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "delta-type opioid receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "kappa-type opioid receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a kappa-type opioid receptor."^^xsd:string) AnnotationAssertion(rdfs:label "kappa-type opioid receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "mu-type opioid receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "mu-type opioid receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a mu-type opioid receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nociceptin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a nociceptin receptor."^^xsd:string) AnnotationAssertion( "nociceptin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "orexigenic neuropeptide QRFP receptor binding"^^xsd:string) AnnotationAssertion( "orexigenic neuropeptide QRFP receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an orexigenic neuropeptide QRFP receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxytocin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an oxytocin receptor."^^xsd:string) AnnotationAssertion( "oxytocin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "parathyroid hormone receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a parathyroid hormone receptor."^^xsd:string) AnnotationAssertion( "parathyroid hormone receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type 1 parathyroid hormone receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1 parathyroid hormone receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 1 parathyroid hormone receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "PACAP receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "pituitary adenylate cyclase-activating polypeptide receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "pituitary adenylate cyclase activating peptide receptor binding"^^xsd:string) AnnotationAssertion( "pituitary adenylate cyclase-activating peptide receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a pituitary adenylate cyclase-activating polypeptide receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "platelet activating factor receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a platelet activating factor receptor."^^xsd:string) AnnotationAssertion( "platelet activating factor receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "prolactin-releasing peptide receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a prolactin-releasing peptide receptor."^^xsd:string) AnnotationAssertion(rdfs:label "prolactin-releasing peptide receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a prostanoid receptor."^^xsd:string) AnnotationAssertion( "prostanoid receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "prostanoid receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a prostaglandin D2 receptor."^^xsd:string) AnnotationAssertion( "prostaglandin D2 receptor ligand"^^xsd:string) AnnotationAssertion( "prostanoid DP receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "prostaglandin D2 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an EP1 subtype prostaglandin E2 receptor."^^xsd:string) AnnotationAssertion( "EP1 subtype prostaglandin E2 receptor ligand"^^xsd:string) AnnotationAssertion( "prostanoid EP1 receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "EP1 subtype prostaglandin E2 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "prostanoid EP2 receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an EP2 subtype prostaglandin E2 receptor."^^xsd:string) AnnotationAssertion( "EP2 subtype prostaglandin E2 receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "EP2 subtype prostaglandin E2 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "EP3 subtype prostaglandin E2 receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an EP3 subtype prostaglandin E2 receptor."^^xsd:string) AnnotationAssertion(rdfs:label "EP3 subtype prostaglandin E2 receptor binding"^^xsd:string) AnnotationAssertion( "prostanoid EP3 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "EP4 subtype prostaglandin E2 receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "EP4 subtype prostaglandin E2 receptor binding"^^xsd:string) AnnotationAssertion( "prostanoid EP4 receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with an EP4 subtype prostaglandin E2 receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a prostaglandin F2-alpha receptor."^^xsd:string) AnnotationAssertion(rdfs:label "prostaglandin F2-alpha receptor binding"^^xsd:string) AnnotationAssertion( "prostaglandin F2-alpha receptor ligand"^^xsd:string) AnnotationAssertion( "prostanoid FP receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "prostacyclin receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a prostacyclin receptor."^^xsd:string) AnnotationAssertion( "prostanoid IP receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "prostacyclin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "prostanoid TP receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a thromboxane A2 receptor."^^xsd:string) AnnotationAssertion( "thromboxane A2 receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "thromboxane A2 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "proteinase activated receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a proteinase activated receptor."^^xsd:string) AnnotationAssertion(rdfs:label "proteinase activated receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1 proteinase activated receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 1 proteinase activated receptor binding"^^xsd:string) AnnotationAssertion( "type 1 proteinase activated receptor ligand"^^xsd:string) AnnotationAssertion( "thrombin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 2 proteinase activated receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 2 proteinase activated receptor binding"^^xsd:string) AnnotationAssertion( "type 2 proteinase activated receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 3 proteinase activated receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 3 proteinase activated receptor."^^xsd:string) AnnotationAssertion( "type 3 proteinase activated receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 4 proteinase activated receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 4 proteinase activated receptor."^^xsd:string) AnnotationAssertion( "type 4 proteinase activated receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a secretin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "secretin receptor binding"^^xsd:string) AnnotationAssertion( "secretin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a somatostatin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "somatostatin receptor binding"^^xsd:string) AnnotationAssertion( "somatostatin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 1 somatostatin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1 somatostatin receptor."^^xsd:string) AnnotationAssertion( "type 1 somatostatin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 2 somatostatin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 2 somatostatin receptor binding"^^xsd:string) AnnotationAssertion( "type 2 somatostatin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 3 somatostatin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 3 somatostatin receptor binding"^^xsd:string) AnnotationAssertion( "type 3 somatostatin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 4 somatostatin receptor binding"^^xsd:string) AnnotationAssertion( "type 4 somatostatin receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 4 somatostatin receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type 5 somatostatin receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 5 somatostatin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 5 somatostatin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a taste receptor."^^xsd:string) AnnotationAssertion(rdfs:label "taste receptor binding"^^xsd:string) AnnotationAssertion( "taste receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1 member 1 taste receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 1 member 1 taste receptor binding"^^xsd:string) AnnotationAssertion( "type 1 member 1 taste receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1 member 2 taste receptor."^^xsd:string) AnnotationAssertion( "type 1 member 2 taste receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 1 member 2 taste receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sweet taste receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1 member 3 taste receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type 1 member 3 taste receptor binding"^^xsd:string) AnnotationAssertion( "type 1 member 3 taste receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "urotensin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "urotensin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a urotensin receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "vasoactive intestinal polypeptide receptor binding"^^xsd:string) AnnotationAssertion( "VIP receptor binding"^^xsd:string) AnnotationAssertion( "vasoactive intestinal polypeptide receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a vasoactive intestinal polypeptide receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 1 vasoactive intestinal polypeptide receptor binding"^^xsd:string) AnnotationAssertion( "type 2 PACAP receptor binding"^^xsd:string) AnnotationAssertion( "type 1 vasoactive intestinal polypeptide receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 1 vasoactive intestinal polypeptide receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a type 2 vasoactive intestinal polypeptide receptor."^^xsd:string) AnnotationAssertion( "type 2 vasoactive intestinal polypeptide receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type 2 vasoactive intestinal polypeptide receptor binding"^^xsd:string) AnnotationAssertion( "type 3 PACAP receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "vasopressin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a vasopressin receptor."^^xsd:string) AnnotationAssertion( "vasopressin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a V1A vasopressin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "V1A vasopressin receptor binding"^^xsd:string) AnnotationAssertion( "V1A vasopressin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "V1B vasopressin receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a V1B vasopressin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "V1B vasopressin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a V2 vasopressin receptor."^^xsd:string) AnnotationAssertion( "V2 vasopressin receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "V2 vasopressin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Enables the directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion(rdfs:label "vitamin B6 transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyridoxal transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "pyridoxal transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Enables the directed movement of pyridoxal across a membrane into, out of or within a cell, or between cells. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyridoxal phosphate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Enables the directed movement of pyridoxal phosphate into, out of or within a cell, or between cells; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyridoxamine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Enables the directed movement of pyridoxamine into, out of or within a cell, or between cells. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Enables the directed movement of pyridoxine across a membrane into, out of or within a cell, or between cells. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate."^^xsd:string) AnnotationAssertion( "pyridoxine transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyridoxine transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:26666"^^xsd:string) Annotation( "EC:6.2.1.3"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + a short-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; short-chain fatty acids are fatty acids with a chain length of less than C6."^^xsd:string) AnnotationAssertion(rdfs:label "short-chain fatty acid-CoA ligase activity"^^xsd:string) AnnotationAssertion( "short-chain-fatty-acid-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "short-chain fatty-acid-CoA ligase activity"^^xsd:string) AnnotationAssertion( "short-chain fatty acid activation"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "medium-chain fatty acid-CoA ligase activity"^^xsd:string) AnnotationAssertion( "medium-chain-fatty-acid-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "medium-chain fatty-acid-CoA ligase activity"^^xsd:string) AnnotationAssertion( "medium-chain fatty acid activation"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:59554"^^xsd:string) Annotation( "EC:6.2.1.3"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + a medium-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a medium-chain fatty acid is any fatty acid with a chain length of between C6 and C12."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "very long-chain fatty acid-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:27283"^^xsd:string) Annotation( "EC:6.2.1.3"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + a very-long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a very long-chain fatty acid is a fatty acid which has a chain length greater than C22."^^xsd:string) AnnotationAssertion( "very-long-chain fatty acid-CoA ligase activity"^^xsd:string) AnnotationAssertion( "very-long-chain fatty acid activation"^^xsd:string) AnnotationAssertion( "very-long-chain-fatty-acid-CoA ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cortisol receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12511169"^^xsd:string) "Interacting selectively and non-covalently with a cortisol receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12511169"^^xsd:string) "Interacting selectively and non-covalently with a mineralocorticoid receptor."^^xsd:string) AnnotationAssertion(rdfs:label "mineralocorticoid receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cortisol receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12511169"^^xsd:string) "Combining with cortisol and transmitting the signal within the cell to trigger a change in cell activity or function."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-alanyl-histamine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rc"^^xsd:string) Annotation( "PMID:16299587"^^xsd:string) "Catalysis of the reaction: N-beta-alanyl histamine + H2O = histamine + beta-alanine."^^xsd:string) AnnotationAssertion( "carcinine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "energy transducer activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "The biological transducer activity that accepts energy and converts it to another form, often by transfer to another molecule within the cell."^^xsd:string) AnnotationAssertion( "light harvesting activity"^^xsd:string) AnnotationAssertion( "photon capture"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "light transducer activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mlg"^^xsd:string) "Absorbing energy from one or more photons and transferring their energy to another molecule, usually a protein, within the cell."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "IGF-I binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with insulin-like growth factor I."^^xsd:string) AnnotationAssertion(rdfs:label "insulin-like growth factor I binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "insulin-like growth factor II binding"^^xsd:string) AnnotationAssertion( "IGF-II binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with insulin-like growth factor II."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thioesterase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dl"^^xsd:string) "Interacting selectively and non-covalently with any thioesterase enzyme."^^xsd:string) AnnotationAssertion( "thiolesterase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dl"^^xsd:string) Annotation( "GOC:jsg"^^xsd:string) Annotation( "PMID:15632291"^^xsd:string) "Interacting selectively and non-covalently with the N-terminus of a protein that has the potential to be, or has been, modified by N-terminal myristoylation. Binding affinity is typically altered by myristoylation; for example, N-terminal myristoylation of HIV Nef increases its affinity for calmodulin."^^xsd:string) AnnotationAssertion(rdfs:label "N-terminal myristoylation domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "D-glucosyltransferase"^^xsd:string) AnnotationAssertion( "T-enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.24"^^xsd:string) "oligoglucan-branching glycosyltransferase activity"^^xsd:string) AnnotationAssertion( "1,4-alpha-D-glucan 6-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1,4-alpha-glucan 6-alpha-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "1,4-alpha-D-glucan:1,4-alpha-D-glucan(D-glucose) 6-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.24"^^xsd:string) "Catalysis of the transfer an alpha-D-glucosyl residue in a (1->4)-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a (1->4)-alpha-D-glucan."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "interleukin-28 receptor ligand"^^xsd:string) AnnotationAssertion( "IL-28"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-28 receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rph"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-28 receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12210903"^^xsd:string) "Catalysis of the reaction: 2-methylbutanol + NADP+ = 2-methylbutanal + NADPH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "2-methylbutanol:NADP oxidoreductase activity"^^xsd:string) AnnotationAssertion( "2-methylbutyraldehyde reductase (NADP) activity"^^xsd:string) AnnotationAssertion( "2-methylbutanal reductase (NADP) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a light chain of a myosin complex."^^xsd:string) AnnotationAssertion(rdfs:label "myosin light chain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "myosin head/neck binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the head/neck region of a myosin heavy chain."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "myosin tail binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the tail region of a myosin heavy chain."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a light chain of a myosin I complex."^^xsd:string) AnnotationAssertion(rdfs:label "myosin I light chain binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the head/neck region of a myosin I heavy chain."^^xsd:string) AnnotationAssertion(rdfs:label "myosin I head/neck binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the tail region of a myosin I heavy chain."^^xsd:string) AnnotationAssertion(rdfs:label "myosin I tail binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a light chain of a myosin II complex."^^xsd:string) AnnotationAssertion(rdfs:label "myosin II light chain binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the head/neck region of a myosin II heavy chain."^^xsd:string) AnnotationAssertion(rdfs:label "myosin II head/neck binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "myosin II tail binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the tail region of a myosin II heavy chain."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "myosin heavy chain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a heavy chain of a myosin complex."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a heavy chain of a myosin I complex."^^xsd:string) AnnotationAssertion(rdfs:label "myosin I heavy chain binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a heavy chain of a myosin II complex."^^xsd:string) AnnotationAssertion(rdfs:label "myosin II heavy chain binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NAD-dependent histone deacetylase activity (H3-K14 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.17"^^xsd:string) Annotation( "EC:3.5.1.98"^^xsd:string) Annotation( "RHEA:24551"^^xsd:string) "Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "clathrin heavy chain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a clathrin heavy chain."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "clathrin light chain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a clathrin light chain."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:rph"^^xsd:string) "Interacting selectively and non-covalently with bile acids, any of a group of steroid carboxylic acids occurring in bile."^^xsd:string) AnnotationAssertion(rdfs:label "bile acid binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Type IV restriction enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "Type IV site-specific deoxyribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12654995"^^xsd:string) "Catalysis of the endonucleolytic cleavage of DNA in a site specific manner. Cleavage is dependent on the presence of a specific recognition site in the DNA which must be modified (e.g. methylated, hydroxymethylated, glucosyl-hydroxymethylated)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NACHT domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "Interacting selectively and non-covalently with a NACHT (NAIP, CIITA, HET-E and TP1) domain. The NACHT domain consists of seven distinct conserved motifs, including an ATP/GTPase specific P-loop, a Mg(2+)-binding site and five more specific motifs."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "PAAD domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "Interacting selectively and non-covalently with a Pyrin (PAAD/DAPIN) domain, a protein-protein interaction domain that has the same fold as the Death domain."^^xsd:string) AnnotationAssertion(rdfs:label "Pyrin domain binding"^^xsd:string) AnnotationAssertion( "DAPIN domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "SAM domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mcc"^^xsd:string) Annotation( "PMID:16337230"^^xsd:string) "Interacting selectively and non-covalently with a SAM (Sterile Alpha Motif) domain, which is a 70-amino acid protein sequence that participates in protein-protein, protein-lipid, and protein-RNA interactions and is conserved from lower to higher eukaryotes."^^xsd:string) AnnotationAssertion( "Sterile Alpha Motif domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.289"^^xsd:string) "D-glucitol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.289"^^xsd:string) Annotation( "RHEA:14612"^^xsd:string) "Catalysis of the reaction: D-glucitol + NADP(+) = L-sorbose + H(+) + NADPH. The reaction may occur, to a minor extent, in the reverse direction."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.289"^^xsd:string) "Sou1p"^^xsd:string) AnnotationAssertion(rdfs:label "sorbose reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone deacetylase activity (H3-K9 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.17"^^xsd:string) Annotation( "EC:3.5.1.98"^^xsd:string) Annotation( "RHEA:24551"^^xsd:string) "Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alkylated DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with alkylated residues in DNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:16679453"^^xsd:string) "Interacting selectively and non-covalently with O6-alkylguanine adducts in DNA."^^xsd:string) AnnotationAssertion(rdfs:label "O6-alkylguanine-DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA insertion or deletion binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with double-stranded DNA containing insertions or deletions."^^xsd:string) AnnotationAssertion( "insertion binding"^^xsd:string) AnnotationAssertion( "DNA insertion binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "cytosine/adenine mispair binding"^^xsd:string) AnnotationAssertion(rdfs:label "adenine/cytosine mispair binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with double-stranded DNA containing an A/C mispair."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "C/A mispair binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "A/C mispair binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "T/G mispair binding"^^xsd:string) AnnotationAssertion(rdfs:label "guanine/thymine mispair binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "thymine/guanine mispair binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with double-stranded DNA containing a G/T mispair."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "G/T mispair binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with double-stranded DNA containing a single base insertion or deletion."^^xsd:string) AnnotationAssertion(rdfs:label "single base insertion or deletion binding"^^xsd:string) AnnotationAssertion( "single base insertion binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with double-stranded DNA containing a dinucleotide insertion or deletion."^^xsd:string) AnnotationAssertion( "dinucleotide insertion binding"^^xsd:string) AnnotationAssertion(rdfs:label "dinucleotide insertion or deletion binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "single adenine insertion binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with double-stranded DNA containing a single adenine insertion or a deletion that results in an unpaired adenine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with double-stranded DNA containing a single cytosine insertion or a deletion that results in an unpaired cytosine."^^xsd:string) AnnotationAssertion(rdfs:label "single cytosine insertion binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with double-stranded DNA containing a single guanine insertion or a deletion that results in an unpaired guanine."^^xsd:string) AnnotationAssertion(rdfs:label "single guanine insertion binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "single thymine insertion binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with double-stranded DNA containing a single thymine insertion or a deletion that results in an unpaired thymine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "succinic semialdehyde dehydrogenase binding"^^xsd:string) AnnotationAssertion(rdfs:label "succinate-semialdehyde dehydrogenase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with succinate-semialdehyde dehydrogenase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiosulfate(out) = ADP + phosphate + thiosulfate(in)."^^xsd:string) AnnotationAssertion(rdfs:label "thiosulfate transmembrane-transporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with double-stranded DNA containing a dinucleotide repeat insertion or a deletion resulting in unpaired dinucleotide repeats."^^xsd:string) AnnotationAssertion(rdfs:label "dinucleotide repeat insertion binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a small conjugating protein such as ubiquitin or a ubiquitin-like protein."^^xsd:string) AnnotationAssertion(rdfs:label "small conjugating protein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "SUMO binding"^^xsd:string) AnnotationAssertion( "Smt3 binding"^^xsd:string) AnnotationAssertion( "Smt3 monomer binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the small ubiquitin-like protein SUMO."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Smt3 polymer binding"^^xsd:string) AnnotationAssertion(rdfs:label "SUMO polymer binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a polymer of the small ubiquitin-like protein SUMO."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "acrosin light chain binding"^^xsd:string) AnnotationAssertion( "acrosin heavy chain binding"^^xsd:string) AnnotationAssertion(rdfs:label "acrosin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12398221"^^xsd:string) "Interacting selectively and non-covalently with acrosin, a protein that is found in the acrosomes of sperm and possesses protease and carbohydrate binding activities."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucosaminyl-phosphotidylinositol O-acyltransferase activity"^^xsd:string) AnnotationAssertion( "GPI-inositol acyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "Reactome:REACT_1049.1"^^xsd:string) "Catalysis of the reaction: glucosaminyl-phosphotidylinositol + fatty acyl-CoA = glucosaminyl-acyl-phosphotidylinositol + CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "riboflavin transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rn"^^xsd:string) Annotation( "PMID:16204239"^^xsd:string) "Facilitates the directed movement of riboflavin into, out of or within a cell, or between cells. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phosphatidylinositol 3-phosphate binding"^^xsd:string) AnnotationAssertion( "PtdIns-3-P binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:10209156"^^xsd:string) Annotation( "PMID:11395417"^^xsd:string) Annotation( "PMID:11557775"^^xsd:string) "Interacting selectively and non-covalently with phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol-3-phosphate binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "tRNA(Ile)-lysidine synthetase activity"^^xsd:string) AnnotationAssertion( "tRNA(Ile)-2-lysyl-cytidine synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA(Ile)-lysidine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14527414"^^xsd:string) "Catalysis of the ligation of lysine onto the cytidine residue present at the wobble position (usually position 34) of an AUA-specific isoleucine tRNA, to form the derivative lysidine. This modification converts both the codon specificity of tRNA(Ile) from AUG to AUA and its amino acid specificity from methionine to isoleucine."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of phosphodiester bonds in double-stranded RNA molecules."^^xsd:string) AnnotationAssertion( "dsRNA-specific RNase activity"^^xsd:string) AnnotationAssertion( "dsRNA-specific ribonuclease activity"^^xsd:string) AnnotationAssertion( "double-stranded RNA-specific RNase activity"^^xsd:string) AnnotationAssertion(rdfs:label "double-stranded RNA-specific ribonuclease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with oxidized residues in DNA."^^xsd:string) AnnotationAssertion( "oxidised DNA binding"^^xsd:string) AnnotationAssertion(rdfs:label "oxidized DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidized purine DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:26386"^^xsd:string) "oxidized purine base DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with oxidized purine residues in DNA."^^xsd:string) AnnotationAssertion( "oxidised purine DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:26386"^^xsd:string) "oxidized purine nucleobase DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:26432"^^xsd:string) "oxidized pyrimidine base DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:26432"^^xsd:string) "oxidized pyrimidine nucleobase DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with oxidized pyrimidine residues in DNA."^^xsd:string) AnnotationAssertion( "oxidised pyrimidine DNA binding"^^xsd:string) AnnotationAssertion(rdfs:label "oxidized pyrimidine DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "gamma-delta T cell receptor activity"^^xsd:string) AnnotationAssertion( "T cell receptor activity"^^xsd:string) AnnotationAssertion( "alpha-beta T cell receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "MHC class I receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with an MHC class Ib protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families."^^xsd:string) AnnotationAssertion(rdfs:label "MHC class Ib receptor activity"^^xsd:string) AnnotationAssertion( "T cell receptor activity"^^xsd:string) AnnotationAssertion( "alpha-beta T cell receptor activity"^^xsd:string) AnnotationAssertion( "gamma-delta T cell receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0781735149"^^xsd:string) "Combining with an MHC class II protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "alpha-beta T cell receptor activity"^^xsd:string) AnnotationAssertion( "gamma-delta T cell receptor activity"^^xsd:string) AnnotationAssertion( "T cell receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "MHC class II receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "inhibitory MHC class I receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "PMID:11858820"^^xsd:string) Annotation( "PMID:9368779"^^xsd:string) Annotation( "PMID:9597134"^^xsd:string) "Combining with a MHC class I protein complex to mediate signaling that inhibits activation of a lymphocyte."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "activating MHC class I receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "PMID:11858820"^^xsd:string) Annotation( "PMID:9597134"^^xsd:string) "Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "Pfam:PF00632"^^xsd:string) "Interacting selectively and non-covalently with a HECT, 'Homologous to the E6-AP Carboxyl Terminus', domain of a protein."^^xsd:string) AnnotationAssertion(rdfs:label "HECT domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules)."^^xsd:string) AnnotationAssertion(rdfs:label "protein complex binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mismatch repair complex binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with a mismatch repair complex."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "MutLalpha complex binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with the mismatch repair complex MutLalpha."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with the mismatch repair complex MutLbeta."^^xsd:string) AnnotationAssertion(rdfs:label "MutLbeta complex binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "MutSalpha complex binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with the mismatch repair complex MutSalpha."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with the mismatch repair complex MutSbeta."^^xsd:string) AnnotationAssertion(rdfs:label "MutSbeta complex binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "PNR element binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9819411"^^xsd:string) "Interacting selectively and non-covalently with a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes."^^xsd:string) AnnotationAssertion(rdfs:label "purine-rich negative regulatory element binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "PMD binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:pg"^^xsd:string) Annotation( "PMID:9119069"^^xsd:string) "Interacting selectively and non-covalently with the GTPase protein binding domain (GDB) domain of a protein. The GBD is a short motif, including a minimum region of 16 amino acids, identified in proteins that bind to small GTPases such as Cdc42 and Rac."^^xsd:string) AnnotationAssertion(Annotation( "PMID:9119069"^^xsd:string) "Cdc42/Rac interactive binding motif binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "P21-Rho-binding domain binding"^^xsd:string) AnnotationAssertion(rdfs:label "GBD domain binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9119069"^^xsd:string) "CRIB motif binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-N-acetylgalactosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.53"^^xsd:string) "beta-acetylgalactosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.53"^^xsd:string) "N-acetylgalactosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.53"^^xsd:string) "Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.53"^^xsd:string) "N-acetyl-beta-galactosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.53"^^xsd:string) "beta-N-acetyl-D-galactosaminide N-acetylgalactosaminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.53"^^xsd:string) "beta-D-N-acetylgalactosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.53"^^xsd:string) "N-acetyl-beta-D-galactosaminidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.74"^^xsd:string) "NAD(P)H-dependent alkenal/one oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.74"^^xsd:string) "n-alkanal:NAD(P)+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-alkenal reductase [NAD(P)] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.74"^^xsd:string) Annotation( "PMID:16299173"^^xsd:string) "Catalysis of the reaction: n-alkanal + NAD(P)+ = alk-2-enal + NAD(P)H + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:14657372"^^xsd:string) Annotation( "PMID:16448336"^^xsd:string) "Catalysis of the reaction: pheophorbide a + reduced ferredoxin + 2 O2 = red chlorophyll catabolite + oxidized ferredoxin + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "pheophorbide a oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11030549"^^xsd:string) Annotation( "PMID:13129921"^^xsd:string) "Catalysis of the NADPH-dependent 7-O-4' reduction of phenylcoumaran lignans to the corresponding diphenols; for example, catalysis of the reaction: dehydrodiconiferyl alcohol + NADPH + H+ = isodihydrodehydrodiconiferyl alcohol + NADP+."^^xsd:string) AnnotationAssertion( "PCBER activity"^^xsd:string) AnnotationAssertion(rdfs:label "phenylcoumaran benzylic ether reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA hairpin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with DNA containing a hairpin. A hairpin structure forms when a DNA strand folds back on itself and intrachain base pairing occurs between inverted repeat sequences."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "maltose alpha-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-2141"^^xsd:string) "Catalysis of the reaction: alpha-maltose + H2O = 2 alpha-D-glucose."^^xsd:string) AnnotationAssertion( "maltase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the removal of a methyl group from a substrate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the removal of a methyl group from a histone."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the removal of a methyl group from lysine at position 4 of the histone H3 protein."^^xsd:string) AnnotationAssertion(rdfs:label "histone demethylase activity (H3-K4 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16362057"^^xsd:string) "Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 9) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 9 of the histone H3 protein."^^xsd:string) AnnotationAssertion(rdfs:label "histone demethylase activity (H3-K9 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "muramyl dipeptide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "Interacting selectively and non-covalently, in a non-covalent manner, with muramyl dipeptide; muramyl dipeptide is derived from peptidoglycan."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "amino acid-exporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(in) -> ADP + phosphate + amino acid(out)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cysteine(in) -> ADP + phosphate + cysteine(out)."^^xsd:string) AnnotationAssertion(rdfs:label "cysteine-exporting ATPase activity"^^xsd:string) AnnotationAssertion( "cysteine exporter"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out) -> ADP + phosphate + amino acid(in)."^^xsd:string) AnnotationAssertion(rdfs:label "amino acid-importing ATPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "D-methionine exporter"^^xsd:string) AnnotationAssertion(rdfs:label "D-methionine-exporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(in) -> ADP + phosphate + D-methionine(out)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "D-methionine importer"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out) -> ADP + phosphate + D-methionine(in)."^^xsd:string) AnnotationAssertion(rdfs:label "D-methionine-importing ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "silicon efflux transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "silicon efflux transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:17625566"^^xsd:string) "Catalysis of the transfer of silicon from the inside of the cell to the outside of the cell across a membrane."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "peroxiredoxin-(S-hydroxy-S-oxocysteine) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.98.2"^^xsd:string) "Srx1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.98.2"^^xsd:string) "peroxiredoxin-(S-hydroxy-S-oxocysteine):thiol oxidoreductase [ATP-hydrolysing; peroxiredoxin-(S-hydroxycysteine)-forming]"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.98.2"^^xsd:string) Annotation( "PMID:16102934"^^xsd:string) "Catalysis of the reaction: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R."^^xsd:string) AnnotationAssertion( "sulphiredoxin activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfiredoxin activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "deoxyribonucleoside binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a deoxyribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to deoxyribose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a purine deoxyribonucleoside, a compound consisting of a purine base linked to deoxyribose."^^xsd:string) AnnotationAssertion(rdfs:label "purine deoxyribonucleoside binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a pyrimidine deoxyribonucleoside, a compound consisting of a pyrimidine base linked to deoxyribose."^^xsd:string) AnnotationAssertion(rdfs:label "pyrimidine deoxyribonucleoside binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ribonucleoside binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "purine ribonucleoside binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a purine ribonucleoside, a compound consisting of a purine base linked to ribose."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a pyrimidine ribonucleoside, a compound consisting of a pyrimidine base linked to ribose."^^xsd:string) AnnotationAssertion(rdfs:label "pyrimidine ribonucleoside binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a deoxyribonucleotide, any compound consisting of a deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety."^^xsd:string) AnnotationAssertion(rdfs:label "deoxyribonucleotide binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety."^^xsd:string) AnnotationAssertion(rdfs:label "ribonucleotide binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "purine deoxyribonucleotide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a purine deoxyribonucleotide, any compound consisting of a purine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety."^^xsd:string) AnnotationAssertion(rdfs:label "purine ribonucleotide binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety."^^xsd:string) AnnotationAssertion(rdfs:label "pyrimidine deoxyribonucleotide binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyrimidine ribonucleotide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a pyrimidine ribonucleotide, any compound consisting of a pyrimidine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "adenyl deoxyribonucleotide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with an adenyl deoxyribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety."^^xsd:string) AnnotationAssertion(rdfs:label "adenyl ribonucleotide binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "guanyl deoxyribonucleotide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a guanyl deoxyribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a guanyl ribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety."^^xsd:string) AnnotationAssertion(rdfs:label "guanyl ribonucleotide binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with dAMP, deoxyadenosine monophosphate."^^xsd:string) AnnotationAssertion(rdfs:label "dAMP binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with dADP, deoxyadenosine diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "dADP binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dATP binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with dATP, deoxyadenosine triphosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with dGMP, deoxyguanosine monophosphate."^^xsd:string) AnnotationAssertion(rdfs:label "dGMP binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dGDP binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with dGDP, deoxyguanosine diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with dGTP, deoxyguanosine triphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "dGTP binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "5' to 3' RNA helicase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jp"^^xsd:string) "Catalysis of the unwinding of an RNA helix in the direction 5' to 3'."^^xsd:string) AnnotationAssertion(rdfs:label "5'-3' RNA helicase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ATP-dependent 5'-3' RNA helicase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jp"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix in the direction 5' to 3'."^^xsd:string) AnnotationAssertion( "ATP-dependent 5' to 3' RNA helicase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) "Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group to an oxygen atom on the acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "O-linoleoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phosphatidylcholine:cardiolipin linoleoyltransferase"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylcholine:cardiolipin O-linoleoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group from phosphatidylcholine to an oxygen atom on a cardiolipin molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "copper-dependent protein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) Annotation( "PMID:16884690"^^xsd:string) "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of copper."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cobalt-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "cobalt transporting ATPase activity"^^xsd:string) AnnotationAssertion( "cobalt ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cobalt(out) = ADP + phosphate + cobalt(in)."^^xsd:string) AnnotationAssertion( "cobalt porter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with lead (Pb) ions."^^xsd:string) AnnotationAssertion(rdfs:label "lead ion binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GTPase activating protein binding"^^xsd:string) AnnotationAssertion( "GAP binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a GTPase activating protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "heterotrimeric G-protein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with a heterotrimeric G-protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "SRE binding"^^xsd:string) AnnotationAssertion(rdfs:label "sterol response element binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) Annotation( "PMID:11994399"^^xsd:string) "Interacting selectively and non-covalently with the sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "TNF receptor superfamily binding"^^xsd:string) AnnotationAssertion(rdfs:label "tumor necrosis factor receptor superfamily binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) "Interacting selectively and non-covalently with any member of the tumor necrosis factor receptor superfamily."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "intramolecular proline-rich region binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pf"^^xsd:string) "Interacting selectively and non-covalently with a proline-rich region within the same polypeptide."^^xsd:string) AnnotationAssertion(rdfs:label "intramolecular proline-rich ligand binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcitonin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) "Interacting selectively and non-covalently with calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) Annotation( "PMID:12540833"^^xsd:string) "Catalysis of the reaction: 2 RSH + ROOH = RSSR + ROH + H2O. This reaction is the thiol-dependent conversion of an organic hydroperoxide to the corresponding alcohol."^^xsd:string) AnnotationAssertion(rdfs:label "hydroperoxide reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-xylose:NADP reductase activity"^^xsd:string) AnnotationAssertion( "D-xylose reductase activity"^^xsd:string) AnnotationAssertion( "xylose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12724380"^^xsd:string) Annotation( "PMID:15184173"^^xsd:string) "Catalysis of the reaction: D-xylitol + NADP+ = D-xylose + NADPH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12724380"^^xsd:string) Annotation( "PMID:15184173"^^xsd:string) "Catalysis of the reaction: L-arabitol + NADP+ = L-arabinose + NADPH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "L-arabinose:NADP reductase activity"^^xsd:string) AnnotationAssertion( "arabinose:NADP reductase activity"^^xsd:string) AnnotationAssertion( "arabinose reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kmv"^^xsd:string) "Catalysis of the reaction: palmitoyl-CoA + AH2 + O2 = palmitoleic acid (16:1delta9) + A + 2 H2O."^^xsd:string) AnnotationAssertion( "palmitoyl-CoA delta9-desaturase acitivity"^^xsd:string) AnnotationAssertion(rdfs:label "palmitoyl-CoA 9-desaturase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone acetyltransferase activity (H3-K56 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 56) = CoA + histone H3 N6-acetyl-L-lysine (position 56)."^^xsd:string) AnnotationAssertion( "histone lysine N-acetyltransferase activity (H3-K56 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "sterol carrier activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15889"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a sterol, any steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol."^^xsd:string) AnnotationAssertion(rdfs:label "sterol binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sterol-sensing domain"^^xsd:string) AnnotationAssertion(rdfs:label "sterol sensor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of a sterol."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hf"^^xsd:string) "Catalysis of the reaction: 1D-myo-inositol tetrakisphosphate + ATP = 1D-myo-inositol pentakisphosphate (containing 2-phosphate) + ADP."^^xsd:string) AnnotationAssertion( "inositol-tetrakisphosphate 2-kinase activity"^^xsd:string) AnnotationAssertion( "inositol 1,3,4,6-tetrakisphosphate 2-kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol tetrakisphosphate 2-kinase activity"^^xsd:string) AnnotationAssertion( "1D-myo-inositol-tetrakisphosphate 2-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein complex scaffold"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Functions to provide a physical support for the assembly of a multiprotein complex."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "membrane insertase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14739936"^^xsd:string) "Mediates the integration of proteins into a membrane from the inner side of the membrane. Membrane insertases are highly conserved and include the bacterial YidC family, the plant chloroplast Alb3 family, and the fungal and animal mitochondrial Oxa1/Cox18 family."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) Annotation( "PMID:12406764"^^xsd:string) "Catalysis of the reaction: 5-hydroxyvalerate + NAD+ = 5-oxovalerate + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "5-hydroxyvalerate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with soluble bitter compounds to initiate a change in cell activity. These receptors are responsible for the sense of bitter taste."^^xsd:string) AnnotationAssertion(rdfs:label "bitter taste receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with soluble salty compounds to initiate a change in cell activity. These receptors are responsible for the sense of salty taste."^^xsd:string) AnnotationAssertion(rdfs:label "salty taste receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with soluble sour compounds to initiate a change in cell activity. These receptors are responsible for the sense of sour taste."^^xsd:string) AnnotationAssertion(rdfs:label "sour taste receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with soluble sweet compounds to initiate a change in cell activity. These receptors are responsible for the sense of sweet taste."^^xsd:string) AnnotationAssertion(rdfs:label "sweet taste receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "umami taste receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with soluble umami compounds to initiate a change in cell activity. These receptors are responsible for the sense of umami taste, the savory taste of meats and other foods that are rich in glutamates."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.82"^^xsd:string) "putrescine-alpha-ketoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.82"^^xsd:string) "YgjG"^^xsd:string) AnnotationAssertion( "PAT activity"^^xsd:string) AnnotationAssertion(rdfs:label "butane-1,4-diamine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.82"^^xsd:string) "putrescine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.82"^^xsd:string) Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O."^^xsd:string) AnnotationAssertion( "putrescine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.82"^^xsd:string) "putrescine:alpha-ketoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.82"^^xsd:string) "putrescine:2-oxoglutarate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with an acetylcholine receptor."^^xsd:string) AnnotationAssertion(rdfs:label "acetylcholine receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ubiquitin activating enzyme binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a ubiquitin activating enzyme, any of the E1 proteins."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a progesterone receptor."^^xsd:string) AnnotationAssertion(rdfs:label "progesterone receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12727870"^^xsd:string) Annotation( "PMID:15455074"^^xsd:string) Annotation( "PMID:16004875"^^xsd:string) "Interacting selectively and non-covalently with the FFAT motif, a short motif containing diphenylalanine in an acidic tract that targets proteins to the cytosolic surface of the ER and to the nuclear membrane by binding directly to members of the VAP (VAMP-associated protein) protein family."^^xsd:string) AnnotationAssertion(rdfs:label "FFAT motif binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oligogalacturonide transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligogalacturonide(out) = ADP + phosphate + oligogalacturonide(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oligogalacturonide transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of oligogalacturonide from one side of the membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase kinase."^^xsd:string) AnnotationAssertion( "MAPKKKK binding"^^xsd:string) AnnotationAssertion(rdfs:label "mitogen-activated protein kinase kinase kinase kinase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.232"^^xsd:string) "initiation-specific alpha-1,6-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.232"^^xsd:string) "GDP-mannose:glycolipid 1,6-alpha-D-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.232"^^xsd:string) Annotation( "GOC:mcc"^^xsd:string) Annotation( "PMID:16878994"^^xsd:string) "Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->6)-D-mannosyl-D-mannose linkage."^^xsd:string) AnnotationAssertion(rdfs:label "glycolipid 6-alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.232"^^xsd:string) "GDP-mannose:oligosaccharide 1,6-alpha-D-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.232"^^xsd:string) "GDP-mannose:oligosaccharide 6-alpha-D-mannosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein-DNA loading ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "DNA-protein loading ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the assembly of a protein or protein complex onto a DNA molecule."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.27"^^xsd:string) "SMS1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.27"^^xsd:string) Annotation( "RHEA:18768"^^xsd:string) "Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + ceramide = 1,2-diacyl-sn-glycerol + sphingomyelin."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.27"^^xsd:string) "ceramide:phosphatidylcholine cholinephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.27"^^xsd:string) "SM synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.27"^^xsd:string) "SMS2"^^xsd:string) AnnotationAssertion(rdfs:label "sphingomyelin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.27"^^xsd:string) "phosphatidylcholine:ceramide cholinephosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) Annotation( "PMID:9659400"^^xsd:string) "Catalysis of the cyclization of double bonds in prosolanapyrone II to form (-)-solanapyrone A."^^xsd:string) AnnotationAssertion(rdfs:label "solanapyrone synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "macrophomate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:38228"^^xsd:string) Annotation( "GOC:cb"^^xsd:string) Annotation( "PMID:10984474"^^xsd:string) "Catalysis of the reaction: a 2-pyrone + oxalacetate = macrophomate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "calcium- and calmodulin-dependent protein phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:15359118"^^xsd:string) "Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin."^^xsd:string) AnnotationAssertion( "calcium/calmodulin-dependent protein phosphatase activity"^^xsd:string) AnnotationAssertion( "calcineurin activity"^^xsd:string) AnnotationAssertion(rdfs:label "calmodulin-dependent protein phosphatase activity"^^xsd:string) AnnotationAssertion( "Ca2+/CaM-dependent protein phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "TXNPx activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: tryparedoxin + hydrogen peroxide = tryparedoxin disulfide + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "tryparedoxin peroxidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "diphosphoinositol-pentakisphosphate 5-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17412958"^^xsd:string) "Catalysis of the reaction: ATP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, and ATP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate."^^xsd:string) AnnotationAssertion( "IP7 5-kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol heptakisphosphate 5-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-1,4-glucan synthase activity"^^xsd:string) AnnotationAssertion( "1,4-alpha-glucan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17472966"^^xsd:string) "Catalysis of the reaction: RDP-glucose + [alpha-D-glucosyl-(1,4)]n = RDP + [alpha-D-glucosyl-(1,4)]n+1, where RDP is ADP or UDP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "RNase P RNA binding"^^xsd:string) AnnotationAssertion(rdfs:label "ribonuclease P RNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pg"^^xsd:string) Annotation( "PMID:11455963"^^xsd:string) "Interacting selectively and non-covalently with the RNA subunit of ribonuclease P."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-1,4-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion( "beta-1,4-GalNAc transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming a beta-1,4 linkage."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "UDP-GalNAc:Neu5Ac-alpha-2-Gal-beta-1-R beta-1,4-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-N-acetylgalactosamine:N-acetylneuraminyl-alpha-2,3-galactosyl-beta-R 1,4-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion( "Sda beta 1,4GalNAc transferase"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12678917"^^xsd:string) Annotation( "PMID:16024623"^^xsd:string) "Catalysis of the reaction: UDP-N-acetylgalactosamine + N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide = UDP + N-acetylgalactosaminyl-N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:32988"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group."^^xsd:string) AnnotationAssertion(rdfs:label "amide binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:16199"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with urea, a water-soluble carboxamide with the structure H2N-CO-NH2."^^xsd:string) AnnotationAssertion(rdfs:label "urea binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + H2O + amide(out) = ADP + phosphate + amide(in)."^^xsd:string) AnnotationAssertion(rdfs:label "amide-transporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "urea-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the reaction: ATP + H2O + urea(out) = ADP + phosphate + urea(in)."^^xsd:string) AnnotationAssertion( "carbamide-transporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "xylose binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:18222"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the D- or L-enantiomer of xylose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Enables the directed movement of 2-aminoethylphosphonate into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion(rdfs:label "2-aminoethylphosphonate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "ciliatine transporter activity"^^xsd:string) AnnotationAssertion( "2-phosphonoethylamine transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the reaction: ATP + H2O + 2-aminoethylphosphonate(out) = ADP + phosphate + 2-aminoethylphosphonate(in)."^^xsd:string) AnnotationAssertion( "2-phosphonoethylamine transporting ATPase activity"^^xsd:string) AnnotationAssertion( "ciliatine transportingATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-aminoethylphosphonate transporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2-phosphonoethylamine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Interacting selectively and non-covalently with 2-aminoethylphosphonate."^^xsd:string) AnnotationAssertion(rdfs:label "2-aminoethylphosphonate binding"^^xsd:string) AnnotationAssertion( "ciliatine binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of cysteine from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "cysteine transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cysteine(out/in) = ADP + phosphate + cysteine(in/out)."^^xsd:string) AnnotationAssertion(rdfs:label "cysteine-transporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-methionine-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out/in) = ADP + phosphate + D-methionine(in/out)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "penicillinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the reaction: a penicillin + H2O = a substituted beta-amino acid derivative of the penicillin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cephalosporinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the reaction: a cephalosporin + H2O = a substituted beta-amino acid derivative of the cephalosporin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "choline binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15354"^^xsd:string) Annotation( "GOC:mlg"^^xsd:string) "Interacting selectively and non-covalently with choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "choline-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of choline across a membrane."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + organic acid(out/in) = ADP + phosphate + organic acid(in/out)."^^xsd:string) AnnotationAssertion(rdfs:label "organic acid-transporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carboxylic acid-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carboxylic acid(out/in) = ADP + phosphate + carboxylic acid(in/out)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "monocarboxylic acid-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monocarboxylic acid(out/in) = ADP + phosphate + monocarboxylic acid(in/out)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ectoine-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ectoine(out/in) = ADP + phosphate + ectoine(in/out)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of hydroxyectoine from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "hydroxyectoine transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + hydroxyectoine(out/in) = ADP + phosphate + hydroxyectoine(in/out)."^^xsd:string) AnnotationAssertion(rdfs:label "hydroxyectoine-transporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-)."^^xsd:string) AnnotationAssertion(rdfs:label "monocarboxylic acid binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with ectoine, 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid."^^xsd:string) AnnotationAssertion(rdfs:label "ectoine binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroxyectoine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Interacting selectively and non-covalently with hydroxyectoine."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:26546"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the D- or L-enantiomer of rhamnose."^^xsd:string) AnnotationAssertion(rdfs:label "rhamnose binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "rhamnose-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + rhamnose(out/in) = ADP + phosphate + rhamnose(in/out)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:17242"^^xsd:string) "Enables the directed movement of dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore."^^xsd:string) AnnotationAssertion(rdfs:label "dehydroascorbic acid transporter activity"^^xsd:string) AnnotationAssertion( "dehydroascorbate transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:14709540"^^xsd:string) "PMP targeting signal binding"^^xsd:string) AnnotationAssertion(rdfs:label "peroxisome membrane targeting sequence binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14709540"^^xsd:string) "PMP targeting signal (mPTS) binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14709540"^^xsd:string) "peroxisomal membrane protein (PMP) targeting signal (mPTS) binding"^^xsd:string) AnnotationAssertion( "mPTS binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rb"^^xsd:string) Annotation( "PMID:15133130"^^xsd:string) Annotation( "PMID:17020786"^^xsd:string) "Interacting selectively and non-covalently with a peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "actin dimerization activity"^^xsd:string) AnnotationAssertion(rdfs:label "actin homodimerization activity"^^xsd:string) AnnotationAssertion( "actin polymerizing activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with an identical actin monomer to form a homodimer."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a UUU codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "phenylalanine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "TTT codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "UUU codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "phenylalanine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "TTC codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a UUC codon."^^xsd:string) AnnotationAssertion(rdfs:label "UUC codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a UUA codon."^^xsd:string) AnnotationAssertion(rdfs:label "UUA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "TTA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "leucine tRNA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "leucine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "TTG codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "UUG codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a UUG codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "TCT codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "UCU codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "serine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a UCU codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "TCC codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "UCC codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "serine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a UCC codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a UCA codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "TCA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "UCA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "serine tRNA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "TCG codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "serine tRNA"^^xsd:string) AnnotationAssertion(rdfs:label "UCG codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a UCG codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UAU codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a UAU codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "tyrosine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "TAT codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "tyrosine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a UAC codon."^^xsd:string) AnnotationAssertion(rdfs:label "UAC codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "TAC codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a UAA codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "TAA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "UAA codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UAG codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a UAG codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "TAG codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "cysteine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "TGT codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "UGU codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a UGU codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UGC codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "TGC codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a UGC codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "cysteine tRNA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a UGA codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "TGA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "UGA codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a UGG codon."^^xsd:string) AnnotationAssertion(rdfs:label "UGG codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "TGG codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "tryptophan tRNA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "CTT codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "CUU codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a CUU codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "leucine tRNA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "leucine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a CUC codon."^^xsd:string) AnnotationAssertion(rdfs:label "CUC codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "CTC codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "CTA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "CUA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "leucine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a CUA codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CUG codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "leucine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "CTG codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a CUG codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "CCT codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a CCU codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "proline tRNA"^^xsd:string) AnnotationAssertion(rdfs:label "CCU codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a CCC codon."^^xsd:string) AnnotationAssertion(rdfs:label "CCC codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "proline tRNA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CCA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "proline tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a CCA codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "proline tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a CCG codon."^^xsd:string) AnnotationAssertion(rdfs:label "CCG codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a CAU codon."^^xsd:string) AnnotationAssertion(rdfs:label "CAU codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "histidine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "CAT codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a CAC codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "histidine tRNA"^^xsd:string) AnnotationAssertion(rdfs:label "CAC codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CAA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a CAA codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "glutamine tRNA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CAG codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "glutamine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a CAG codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CGU codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "arginine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "CGT codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a CGU codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CGC codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "arginine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a CGC codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "arginine tRNA"^^xsd:string) AnnotationAssertion(rdfs:label "CGA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a CGA codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "arginine tRNA"^^xsd:string) AnnotationAssertion(rdfs:label "CGG codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a CGG codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "AUU codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "ATT codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "isoleucine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes an AUU codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "AUC codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "isoleucine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes an AUC codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "ATC codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "ATA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "AUA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "isoleucine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes an AUA codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes an AUG codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "ATG codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "initiator methionine tRNA"^^xsd:string) AnnotationAssertion(rdfs:label "AUG codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "methionine tRNA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ACU codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes an ACU codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "ACT codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "threonine tRNA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ACC codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "threonine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes an ACC codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ACA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes an ACA codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "threonine tRNA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "threonine tRNA"^^xsd:string) AnnotationAssertion(rdfs:label "ACG codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes an ACG codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes an AAU codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "AAT codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "asparagine tRNA"^^xsd:string) AnnotationAssertion(rdfs:label "AAU codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "AAC codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes an AAC codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "asparagine tRNA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes an AAA codon."^^xsd:string) AnnotationAssertion(rdfs:label "AAA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "lysine tRNA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "lysine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes an AAG codon."^^xsd:string) AnnotationAssertion(rdfs:label "AAG codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "AGT codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes an AGU codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "serine tRNA"^^xsd:string) AnnotationAssertion(rdfs:label "AGU codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes an AGC codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "serine tRNA"^^xsd:string) AnnotationAssertion(rdfs:label "AGC codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "AGA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "arginine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes an AGA codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "AGG codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes an AGG codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "arginine tRNA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a GUU codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "valine tRNA"^^xsd:string) AnnotationAssertion(rdfs:label "GUU codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "GTT codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a GUC codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "valine tRNA"^^xsd:string) AnnotationAssertion(rdfs:label "GUC codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "GTC codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "valine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "GTA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a GUA codon."^^xsd:string) AnnotationAssertion(rdfs:label "GUA codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GUG codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "GTG codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a GUG codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "valine tRNA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "alanine tRNA"^^xsd:string) AnnotationAssertion(rdfs:label "GCU codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "GCT codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a GCU codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a GCC codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "alanine tRNA"^^xsd:string) AnnotationAssertion(rdfs:label "GCC codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GCA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "alanine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a GCA codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GCG codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "alanine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a GCG codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a GAU codon."^^xsd:string) AnnotationAssertion(rdfs:label "GAU codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "GAT codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "aspartic acid tRNA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GAC codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "aspartic acid tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a GAC codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GAA codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a GAA codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "glutamic acid tRNA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a GAG codon."^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "glutamic acid tRNA"^^xsd:string) AnnotationAssertion(rdfs:label "GAG codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "glycine tRNA"^^xsd:string) AnnotationAssertion(rdfs:label "GGU codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "GGT codon-amino acid adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a GGU codon."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "glycine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a GGC codon."^^xsd:string) AnnotationAssertion(rdfs:label "GGC codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "glycine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a GGA codon."^^xsd:string) AnnotationAssertion(rdfs:label "GGA codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "glycine tRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "A triplet codon-amino acid adaptor activity that recognizes a GGG codon."^^xsd:string) AnnotationAssertion(rdfs:label "GGG codon-amino acid adaptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12184814"^^xsd:string) Annotation( "PMID:17208316"^^xsd:string) "Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "PMID:12184814"^^xsd:string) "MAPK phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "tyrosine-specific MAP kinase phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: MAP kinase tyrosine phosphate + H2O = MAP kinase tyrosine + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase tyrosine phosphatase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "dolichyl-P-Glc:Man7GlcNAc2-PP-dolichyl glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:10336995"^^xsd:string) "Catalysis of the addition of a glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(7)GlcNAc(2)-PP-Dol."^^xsd:string) AnnotationAssertion(rdfs:label "dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate."^^xsd:string) AnnotationAssertion(rdfs:label "protein deacetylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "folate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pde"^^xsd:string) "Catalysis of the reaction: 7,8-dihydrofolate + NADP+ = folate + NADPH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mlg"^^xsd:string) Annotation( "PMID:16261254"^^xsd:string) "Combining with lactoferrin and delivering lactoferrin into the cell via endocytosis. Lactoferrin is an iron-binding glycoprotein which binds ferric iron most efficiently at low pH."^^xsd:string) AnnotationAssertion(rdfs:label "lactoferrin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of lactoferrin from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "lactoferrin transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of transferrin from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "transferrin transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Facilitates the base-pairing of complementary single-stranded RNA."^^xsd:string) AnnotationAssertion(rdfs:label "RNA strand annealing activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.3.16"^^xsd:string) "formyl-coenzyme A transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.16"^^xsd:string) "formyl-CoA oxalate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.16"^^xsd:string) "formyl-CoA:oxalate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.16"^^xsd:string) Annotation( "RHEA:16548"^^xsd:string) "Catalysis of the reaction: formyl-CoA + oxalate = formate + oxalyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "formyl-CoA transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a receptor that possesses protein serine/threonine kinase activity."^^xsd:string) AnnotationAssertion( "transmembrane receptor protein serine/threonine kinase ligand binding"^^xsd:string) AnnotationAssertion(rdfs:label "receptor serine/threonine kinase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "transcription activator binding"^^xsd:string) AnnotationAssertion(rdfs:label "activating transcription factor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "dsDNA-dependent ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of double-stranded DNA, and it drives another reaction."^^xsd:string) AnnotationAssertion(rdfs:label "double-stranded DNA-dependent ATPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA/RNA helicase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: NTP + H2O = NDP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex, i.e. a double helix in which a strand of DNA pairs with a complementary strand of RNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the unwinding of a DNA/RNA duplex in the direction 5' to 3'."^^xsd:string) AnnotationAssertion( "5' to 3' DNA/RNA helicase activity"^^xsd:string) AnnotationAssertion(rdfs:label "5'-3' DNA/RNA helicase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3' to 5' DNA/RNA helicase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the unwinding of a DNA/RNA duplex in the direction 3' to 5'."^^xsd:string) AnnotationAssertion(rdfs:label "3'-5' DNA/RNA helicase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ATP-dependent DNA/RNA helicase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ATP-dependent 3'-5' DNA/RNA helicase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex in the direction 3' to 5'."^^xsd:string) AnnotationAssertion( "ATP-dependent 3' to 5' DNA/RNA helicase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ATP-dependent 5'-3' DNA/RNA helicase activity"^^xsd:string) AnnotationAssertion( "ATP-dependent 5' to 3' DNA/RNA helicase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex in the direction 5' to 3'."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "N-acetylneuraminic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:26667"^^xsd:string) Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0721601465"^^xsd:string) Annotation( "http://www.biology-online.org"^^xsd:string) "Interacting selectively and non-covalently with sialic acid, any of a variety of N- or O- substituted derivatives of neuraminic acid, a nine carbon monosaccharide. Sialic acids often occur in polysaccharides, glycoproteins, and glycolipids in animals and bacteria."^^xsd:string) AnnotationAssertion(rdfs:label "sialic acid binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.5"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a quinone or similar acceptor molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "DNA deadenylation"^^xsd:string) AnnotationAssertion( "DNA de-adenylation"^^xsd:string) AnnotationAssertion( "DNA adenylate hydrolysis activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:16547001"^^xsd:string) Annotation( "PMID:17276982"^^xsd:string) "Catalysis of the reaction: 5'-AMP-DNA + H2O = AMP + DNA; nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus."^^xsd:string) AnnotationAssertion( "DNA 5'-adenylate hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "DNA 5'-adenosine monophosphate hydrolase activity"^^xsd:string) AnnotationAssertion( "AMP-removal activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.186"^^xsd:string) "dTDP-D-galactose:NADP+ 6-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.186"^^xsd:string) "dTDPgalactose 6-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.186"^^xsd:string) "thymidine-diphosphate-galactose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.186"^^xsd:string) "Catalysis of the reaction: dTDP-D-galactose + 2 NADP+ + H2O = dTDP-D-galacturonate + 2 NADPH + 2 H+."^^xsd:string) AnnotationAssertion(rdfs:label "dTDP-galactose 6-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(+)-trans-carveol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.275"^^xsd:string) "(+)-trans-carveol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.275"^^xsd:string) Annotation( "RHEA:14828"^^xsd:string) "Catalysis of the reaction: (1R,5S)-carveol + NAD(+) = (S)-carvone + H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.277"^^xsd:string) "3beta-hydroxysteroid 5beta-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.277"^^xsd:string) "3beta-hydroxy-5beta-steroid:NADP+ 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.277"^^xsd:string) Annotation( "RHEA:22947"^^xsd:string) "Catalysis of the reaction: 3beta-hydroxy-5beta-pregnane-20-one + NADP(+) = 5beta-pregnan-3,20-dione + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.277"^^xsd:string) "3beta-hydroxysteroid 5beta-progesterone oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3beta-hydroxy-5beta-steroid dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3beta-hydroxy-5alpha-steroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.278"^^xsd:string) "3beta-hydroxy-5alpha-steroid:NADP+ 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.278"^^xsd:string) Annotation( "RHEA:18140"^^xsd:string) "Catalysis of the reaction: 3beta-hydroxy-5alpha-pregnane-20-one + NADP(+) = 5alpha-pregnane-3,20-dione + H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.281"^^xsd:string) "GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase (D-rhamnose-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "GDP-4-dehydro-6-deoxy-D-mannose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.281"^^xsd:string) "Rmd"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.281"^^xsd:string) "GDP-6-deoxy-D-lyxo-4-hexulose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.281"^^xsd:string) "Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.281"^^xsd:string) "GDP-4-keto-6-deoxy-D-mannose reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.285"^^xsd:string) "2'-deoxymugineic acid:NAD(P)+ 3''-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3''-deamino-3''-oxonicotianamine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.285"^^xsd:string) "Catalysis of the reaction: 2'-deoxymugineic acid + NAD(P)+ = 3''-deamino-3''-oxonicotianamine + NAD(P)H + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.286"^^xsd:string) "PH1722"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.286"^^xsd:string) "isocitrate(homoisocitrate):NAD+ oxidoreductase (decarboxylating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "isocitrate-homoisocitrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.286"^^xsd:string) "Catalysis of the reactions: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH, and (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate + CO2 + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.286"^^xsd:string) "homoisocitrate-isocitrate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.287"^^xsd:string) "Catalysis of the reaction: D-arabinitol + NADP+ = D-ribulose + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.287"^^xsd:string) "ARD1p"^^xsd:string) AnnotationAssertion(rdfs:label "D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.287"^^xsd:string) "D-arabinitol dehydrogenase 1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.287"^^xsd:string) "NADP+-dependent D-arabinitol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.287"^^xsd:string) "D-arabinitol:NADP+ dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-phosphoerythronate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.290"^^xsd:string) "4-phospho-D-erythronate:NAD+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.290"^^xsd:string) Annotation( "RHEA:18832"^^xsd:string) "Catalysis of the reaction: 4-phospho-D-erythronate + NAD(+) = (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.290"^^xsd:string) "PdxB"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.290"^^xsd:string) "erythronate-4-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.290"^^xsd:string) "PdxB 4PE dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.290"^^xsd:string) "4-O-phosphoerythronate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.290"^^xsd:string) "4PE dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.292"^^xsd:string) Annotation( "RHEA:24211"^^xsd:string) "Catalysis of the reaction: 1,5-anhydro-D-mannitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.292"^^xsd:string) "AFR"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.292"^^xsd:string) "1,5-anhydro-D-mannitol:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.17"^^xsd:string) "Catalysis of the reaction: choline + O2 = betaine aldehyde + hydrogen peroxide."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.17"^^xsd:string) "choline oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "choline:oxygen 1-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "secondary-alcohol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.18"^^xsd:string) "polyvinyl alcohol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.18"^^xsd:string) "secondary alcohol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.18"^^xsd:string) "secondary-alcohol:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.18"^^xsd:string) Annotation( "RHEA:23183"^^xsd:string) "Catalysis of the reaction: O(2) + secondary alcohol = H(2)O(2) + ketone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nucleoside oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.28"^^xsd:string) "nucleoside:oxygen 5'-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.28"^^xsd:string) "Catalysis of the reactions: inosine + O2 = 9-riburonosylhypoxanthine + 2 H2O; (1a) 2 inosine + O2 = 2 5'-dehydroinosine + 2 H2O, and (1b) 2 5'-dehydroinosine + O2 = 2 9-riburonosylhypoxanthine + 2 H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nucleoside oxidase (hydrogen peroxide-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.39"^^xsd:string) "Catalysis of the reactions: adenosine + 2 O2 = 9-riburonosyladenine + 2 hydrogen peroxide; (1a) adenosine + O2 = 5'-dehydroadenosine + hydrogen peroxide, and (1b) 5'-dehydroadenosine + O2 = 9-riburonosyladenine + hydrogen peroxide."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.39"^^xsd:string) "nucleoside:oxygen 5'-oxidoreductase (hydrogen peroxide-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.3"^^xsd:string) "2-ketogluconate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.3"^^xsd:string) "D-gluconate:(acceptor) 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.3"^^xsd:string) "D-gluconate dehydrogenase, 2-keto-D-gluconate-yielding activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.3"^^xsd:string) "D-gluconate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.3"^^xsd:string) "D-gluconate:acceptor 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.3"^^xsd:string) "Catalysis of the reaction: D-gluconate + acceptor = 2-dehydro-D-gluconate + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.3"^^xsd:string) "gluconic dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "gluconate 2-dehydrogenase (acceptor) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.3"^^xsd:string) "gluconic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.3"^^xsd:string) "gluconate oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.29"^^xsd:string) "PDH"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.29"^^xsd:string) "quinone-dependent pyranose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.29"^^xsd:string) "Catalysis of the reactions: pyranose + acceptor = 2-dehydropyranose (or 3-dehydropyranose or 2,3-didehydropyranose) + reduced acceptor, and a pyranoside + acceptor = a 3-dehydropyranoside (or 3,4-didehydropyranoside) + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.29"^^xsd:string) "pyranose-quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.29"^^xsd:string) "pyranose:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.29"^^xsd:string) "pyranose dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyranose dehydrogenase (acceptor) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.30"^^xsd:string) "(2R)-hydroxycarboxylate-viologen-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.30"^^xsd:string) "(2R)-hydroxy-carboxylate:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.30"^^xsd:string) "HVOR"^^xsd:string) AnnotationAssertion(rdfs:label "2-oxo-acid reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.30"^^xsd:string) "Catalysis of the reaction: a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.30"^^xsd:string) "2-oxoacid reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.31"^^xsd:string) "Catalysis of the reaction: (S)-2-hydroxy-2-phenylacetate + acceptor = 2-oxo-2-phenylacetate + reduced acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "(S)-mandelate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.31"^^xsd:string) "MDH"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.31"^^xsd:string) "L(+)-mandelate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.31"^^xsd:string) "(S)-2-hydroxy-2-phenylacetate:acceptor 2-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.4"^^xsd:string) "NADP-acetaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.4"^^xsd:string) "Catalysis of the reaction: an aldehyde + NADP+ + H2O = an acid + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.4"^^xsd:string) "NADP-dependent aldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.4"^^xsd:string) "aldehyde:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aldehyde dehydrogenase (NADP+) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.15"^^xsd:string) "malonic semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.15"^^xsd:string) "Catalysis of the reaction: 3-oxopropanoate + NAD(P)+ + H2O = malonate + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.15"^^xsd:string) "3-oxopropanoate:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "malonate-semialdehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fluoroacetaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.69"^^xsd:string) "fluoroacetaldehyde:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.69"^^xsd:string) "Catalysis of the reaction: fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.7.5"^^xsd:string) "Catalysis of the reaction: an aldehyde + H2O + 2 oxidized ferredoxin = an acid + 2 H+ + 2 reduced ferredoxin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.5"^^xsd:string) "AOR"^^xsd:string) AnnotationAssertion(rdfs:label "aldehyde ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.5"^^xsd:string) "tungsten-containing aldehyde ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.5"^^xsd:string) "aldehyde:ferredoxin oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aldehyde dehydrogenase (FAD-independent) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.99.7"^^xsd:string) "AORDd"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.99.7"^^xsd:string) "aldehyde oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.99.7"^^xsd:string) "aldehyde:acceptor oxidoreductase (FAD-independent) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.99.7"^^xsd:string) "Catalysis of the reaction: an aldehyde + H2O + acceptor = a carboxylate + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.99.7"^^xsd:string) "Mop"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.75"^^xsd:string) "chlorophyllide-a:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.75"^^xsd:string) "Catalysis of the reaction: chlorophyllide a + NADP+ = divinyl chlorophyllide a + NADPH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "divinyl chlorophyllide a 8-vinyl-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.75"^^xsd:string) "[4-vinyl]chlorophyllide a reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.75"^^xsd:string) "4VCR"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "anthocyanidin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.77"^^xsd:string) "Catalysis of the reaction: a flavan-3-ol + 2 NAD(P)+ = an anthocyanidin + 2 NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.77"^^xsd:string) "AtANR"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.77"^^xsd:string) "flavan-3-ol:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.77"^^xsd:string) "ANR"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.77"^^xsd:string) "MtANR"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.78"^^xsd:string) "pretyrosine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.78"^^xsd:string) "arogenic dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arogenate dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.78"^^xsd:string) "Catalysis of the reaction: L-arogenate + NADP+ = L-tyrosine + NADPH + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.78"^^xsd:string) "TyrAAT2"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.78"^^xsd:string) "TyrAAT1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.78"^^xsd:string) "L-arogenate:NADP+ oxidoreductase (decarboxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.78"^^xsd:string) "TyrAa"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.79"^^xsd:string) "Catalysis of the reaction: L-arogenate + NAD(P)+ = L-tyrosine + NAD(P)H + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.79"^^xsd:string) "pretyrosine dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arogenate dehydrogenase [NAD(P)+] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.79"^^xsd:string) "L-arogenate:NAD(P)+ oxidoreductase (decarboxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.79"^^xsd:string) "arogenic dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.3.11"^^xsd:string) "PqqC"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.11"^^xsd:string) "6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,5,6,7,8-octahydroquinoline-2,4-dicarboxylate:oxygen oxidoreductase (cyclizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.11"^^xsd:string) Annotation( "RHEA:10695"^^xsd:string) "Catalysis of the reaction: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O(2) = 2 H(2)O + 2 H(2)O(2) + H(+) + pyrroloquinoline quinone."^^xsd:string) AnnotationAssertion(rdfs:label "pyrroloquinoline-quinone synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.99.21"^^xsd:string) "BbsG"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.21"^^xsd:string) "(R)-benzylsuccinyl-CoA:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(R)-benzylsuccinyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.21"^^xsd:string) "Catalysis of the reaction: (R)-2-benzylsuccinyl-CoA + 2 electron-transferring flavoprotein = (E)-2-benzylidenesuccinyl-CoA + 2 reduced electron-transferring flavoprotein."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.21"^^xsd:string) "(R)-benzylsuccinyl-CoA:(acceptor) oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.1.21"^^xsd:string) "NADH2-dependent aspartate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.21"^^xsd:string) "NADP+-dependent aspartate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.21"^^xsd:string) "NAD-dependent aspartate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aspartate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.21"^^xsd:string) "Catalysis of the reaction: L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.21"^^xsd:string) "L-aspartate:NAD(P)+ oxidoreductase (deaminating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.3.20"^^xsd:string) "Lod"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.20"^^xsd:string) "L-lysine:oxygen 6-oxidoreductase (deaminating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-lysine 6-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.20"^^xsd:string) "marinocine"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.20"^^xsd:string) "LodA"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.20"^^xsd:string) Annotation( "RHEA:22551"^^xsd:string) "Catalysis of the reaction: L-lysine + H(2)O + O(2) = allysine + H(2)O(2) + NH(4)(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.20"^^xsd:string) "L-lysine-epsilon-oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.35"^^xsd:string) "gamma-aminobutyraldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.35"^^xsd:string) "YdcW"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.35"^^xsd:string) "ABALDH"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:1.5.1.35-RXN"^^xsd:string) "Catalysis of the reaction: 1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.35"^^xsd:string) "1-pyrroline:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-pyrroline dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.7.1"^^xsd:string) "5-methyltetrahydrofolate:ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.7.1"^^xsd:string) "5,10-methylenetetrahydrofolate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.7.1"^^xsd:string) "Catalysis of the reaction: 5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin."^^xsd:string) AnnotationAssertion(rdfs:label "methylenetetrahydrofolate reductase (ferredoxin) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "queuine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.13"^^xsd:string) "7-cyano-7-deazaguanine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.13"^^xsd:string) "QueF"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.13"^^xsd:string) Annotation( ) "7-aminomethyl-7-carbaguanine:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "preQ1 synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.13"^^xsd:string) "preQ0 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.13"^^xsd:string) "preQ0 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.13"^^xsd:string) Annotation( "RHEA:13412"^^xsd:string) "Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.13"^^xsd:string) "YkvM"^^xsd:string) AnnotationAssertion( "queuine:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.99.8"^^xsd:string) "Catalysis of the reactions: hydroxylamine + NH3 = hydrazine + H2O, and hydrazine + acceptor = N2 + reduced acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "hydroxylamine oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.99.8"^^xsd:string) "hydroxylamine:acceptor oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.4.9"^^xsd:string) "plant-type 5'-adenylylsulfate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.9"^^xsd:string) "5'-adenylylsulfate reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "adenylyl-sulfate reductase (glutathione) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.9"^^xsd:string) Annotation( "RHEA:14144"^^xsd:string) "Catalysis of the reaction: AMP + glutathione disulfide + H(+) + sulfite = 5'-adenylyl sulfate + 2 glutathione."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.9"^^xsd:string) "AMP,sulfite:oxidized-glutathione oxidoreductase (adenosine-5'-phosphosulfate-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.9"^^xsd:string) "AMP,sulfite:glutathione-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.4.12"^^xsd:string) "SelR"^^xsd:string) AnnotationAssertion( "protein-methionine-R-oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.12"^^xsd:string) "methionine S-oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.12"^^xsd:string) "selenoprotein R"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.12"^^xsd:string) "MsrB"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.12"^^xsd:string) "pMRsr"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.12"^^xsd:string) "peptide-methionine:thioredoxin-disulfide S-oxidoreductase [methionine (R)-S-oxide-forming] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.12"^^xsd:string) "methionine sulfoxide reductase B activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.12"^^xsd:string) "pMSR"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.12"^^xsd:string) "PilB"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.12"^^xsd:string) "SelX"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.12"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) Annotation( "RHEA:24167"^^xsd:string) "Catalysis of the reaction: peptide-L-methionine + H(2)O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin."^^xsd:string) AnnotationAssertion(rdfs:label "peptide-methionine (R)-S-oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.12"^^xsd:string) "methionine sulfoxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.12"^^xsd:string) "methionine S-oxide reductase (R-form oxidizing) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.4.13"^^xsd:string) "methyl sulfoxide reductase I and II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.13"^^xsd:string) "fSMsr"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11169920"^^xsd:string) "methionine-S-oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.13"^^xsd:string) "free-methionine (S)-S-oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.13"^^xsd:string) "L-methionine:oxidized-thioredoxin S-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-methionine:thioredoxin-disulfide S-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.13"^^xsd:string) "methionine sulfoxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.13"^^xsd:string) "acetylmethionine sulfoxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "L-methionine-(S)-S-oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.13"^^xsd:string) "Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-methionine-(R)-S-oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.14"^^xsd:string) "L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (R)-S-oxide-forming] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.14"^^xsd:string) "free-methionine (R)-S-oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.14"^^xsd:string) "FRMsr"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.14"^^xsd:string) "Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (R)-S-oxide + thioredoxin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.14"^^xsd:string) "free met-R-(o) reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone demethylase activity (H3-R2 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the removal of a methyl group from arginine at position 2 of the histone H3 protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.12.99.6"^^xsd:string) "Catalysis of the reaction: H2 + A = AH2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.99.6"^^xsd:string) "hydrogenlyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydrogenase (acceptor) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.99.6"^^xsd:string) "hydrogen-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.99.6"^^xsd:string) "hydrogen:(acceptor) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.99.6"^^xsd:string) "uptake hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.99.6"^^xsd:string) "H2 producing hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.99.6"^^xsd:string) "hydrogen:acceptor oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the removal of a methyl group from arginine at position 3 of the histone H4 protein."^^xsd:string) AnnotationAssertion(rdfs:label "histone demethylase activity (H4-R3 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "linoleate diol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.44"^^xsd:string) "linoleate (8R)-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.44"^^xsd:string) "Catalysis of the reaction: linoleate + O2 = (9Z,12Z)-(7S,8S)-dihydroxyoctadeca-9,12-dienoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.44"^^xsd:string) "linoleate:oxygen 7S,8S-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.44"^^xsd:string) "linoleate 8-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.50"^^xsd:string) "Dke1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.50"^^xsd:string) "acetylacetone dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.50"^^xsd:string) "diketone cleaving dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.50"^^xsd:string) "diketone cleaving enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.50"^^xsd:string) "Catalysis of the reaction: pentane-2,4-dione + O2 = acetate + 2-oxopropanal."^^xsd:string) AnnotationAssertion(rdfs:label "acetylacetone-cleaving enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.50"^^xsd:string) "acetylacetone-cleaving enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.50"^^xsd:string) "acetylacetone:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.52"^^xsd:string) "tryptophan pyrrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.52"^^xsd:string) "IDO"^^xsd:string) AnnotationAssertion(rdfs:label "indoleamine 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.52"^^xsd:string) "D-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.52"^^xsd:string) "Catalysis of the reaction: tryptophan + O2 = N-formylkynurenine. The product of the reaction depends on the substrate; D-tryptophan produces N-formyl-D-kynurenine, and L-tryptophan produces N-formyl-L-kynurenine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.55"^^xsd:string) "sulfur:oxygen oxidoreductase (hydrogen-sulfide- and sulfite-forming) activity"^^xsd:string) AnnotationAssertion( "sulphur oxygenase/reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfur oxygenase/reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.55"^^xsd:string) "SOR"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.55"^^xsd:string) "Catalysis of the reaction: 4 sulfur + 4 H2O + O2 = 2 hydrogen sulfide + 2 bisulfite + 2 H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.55"^^xsd:string) "sulfur oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.12.13"^^xsd:string) "Catalysis of the reaction: Oplophorus luciferin + O2 = oxidized Oplophorus luciferin + CO2 + hnu."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.13"^^xsd:string) "Oplophorus luciferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.13"^^xsd:string) "Oplophorus-luciferin:oxygen 2-oxidoreductase (decarboxylating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "Oplophorus-luciferin 2-monooxygenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.13"^^xsd:string) "D-aldohexoside:(acceptor) 3-oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.13"^^xsd:string) "hexopyranoside-cytochrome c oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.13"^^xsd:string) "D-aldohexoside:acceptor 3-oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.13"^^xsd:string) "D-aldohexopyranoside dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.13"^^xsd:string) "D-aldohexoside:cytochrome c oxidoreductase"^^xsd:string) AnnotationAssertion(rdfs:label "glucoside 3-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.13"^^xsd:string) "Catalysis of the reaction: sucrose + acceptor = 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.21"^^xsd:string) "deoxyamidinoproclavaminate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.21"^^xsd:string) "clavaminic acid synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "clavaminate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.21"^^xsd:string) "clavaminate synthase 2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.21"^^xsd:string) "Catalysis of the reactions: deoxyamidinoproclavaminate + 2-oxoglutarate + O2 = amidinoproclavaminate + succinate + CO2 + H2O; proclavaminate + 2-oxoglutarate + O2 = dihydroclavaminate + succinate + CO2 + 2 H2O; and dihydroclavaminate + 2-oxoglutarate + O2 = clavaminate + succinate + CO2 + 2 H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.22"^^xsd:string) "flavone synthase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.22"^^xsd:string) "FNS I"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.22"^^xsd:string) "flavanone,2-oxoglutarate:oxygen oxidoreductase (dehydrating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.22"^^xsd:string) "Catalysis of the reaction: a flavanone + 2-oxoglutarate + O2 = a flavone + succinate + CO2 + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "flavone synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.24"^^xsd:string) "2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.24"^^xsd:string) "IDS3"^^xsd:string) AnnotationAssertion(rdfs:label "2'-deoxymugineic-acid 2'-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.24"^^xsd:string) Annotation( "RHEA:12203"^^xsd:string) "Catalysis of the reaction: 2'-deoxymugineate + 2-oxoglutarate + O(2) = CO(2) + H(+) + mugineate + succinate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mugineic-acid 3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.25"^^xsd:string) "Catalysis of the reactions: mugineic acid + 2-oxoglutarate + O2 = 3-epihydroxymugineic acid + succinate + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.25"^^xsd:string) "IDS2"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.25"^^xsd:string) "mugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "proline 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.28"^^xsd:string) "L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.28"^^xsd:string) "Catalysis of the reaction: L-proline + 2-oxoglutarate + O2 = cis-3-hydroxy-L-proline + succinate + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.28"^^xsd:string) "P-3-H"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative."^^xsd:string) AnnotationAssertion(rdfs:label "steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "steroid dehydrogenase activity, acting on the CH-CH group of donors"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor, and in which one substrate is a sterol derivative."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.61"^^xsd:string) "2-oxo-1,2-dihydroquinoline 8-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.61"^^xsd:string) "quinolin-2(1H)-one,NADH:oxygen oxidoreductase (8-oxygenating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxyquinoline 8-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.61"^^xsd:string) Annotation( "RHEA:22083"^^xsd:string) "Catalysis of the reaction: H(+) + NADH + O(2) + quinolin-2-ol = H(2)O + NAD(+) + quinoline-2,8-diol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-hydroxyacetophenone monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.84"^^xsd:string) Annotation( ) "(4-hydroxyphenyl)ethan-1-one,NADPH:oxygen oxidoreductase (ester-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.84"^^xsd:string) Annotation( "RHEA:22919"^^xsd:string) "Catalysis of the reaction: 4'-hydroxyacetophenone + H(+) + NADPH + O(2) = 4-hydroxyphenyl acetate + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.84"^^xsd:string) "HAPMO"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.85"^^xsd:string) "Catalysis of the reactions: 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O, and 4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.85"^^xsd:string) "2-(or 4-)dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan,NADPH:oxygen oxidoreductase (cyclizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.85"^^xsd:string) "dimethylallyl-3,6a,9-trihydroxypterocarpan cyclase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glyceollin synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.86"^^xsd:string) "Catalysis of the reaction: apigenin + 2 NADPH + 2 H+ + O2 = 2-hydroxy-2,3-dihydrogenistein + 2 NADP+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.86"^^xsd:string) "2-HIS"^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxyisoflavanone synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.86"^^xsd:string) "apigenin,NADPH:oxygen oxidoreductase (isoflavanone-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.87"^^xsd:string) "liquiritigenin,NADPH:oxygen oxidoreductase (licodione-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.87"^^xsd:string) Annotation( "RHEA:15700"^^xsd:string) "Catalysis of the reaction: H(+) + liquiritigenin + NADPH + O(2) = H(2)O + licodione + NADP(+)."^^xsd:string) AnnotationAssertion(rdfs:label "licodione synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.87"^^xsd:string) "(2S)-flavanone 2-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.88"^^xsd:string) "Catalysis of the reactions: a flavanone + NADPH + H+ + O2 = a 3'-hydroxyflavanone + NADP+ + H2O, and a 3'-hydroxyflavanone + NADPH + H+ + O2 = a 3',5'-dihydroxyflavanone + NADP+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.88"^^xsd:string) "F3',5'H"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.88"^^xsd:string) "flavanone,NADPH:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.88"^^xsd:string) "F3'5'H"^^xsd:string) AnnotationAssertion(rdfs:label "flavonoid 3',5'-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.89"^^xsd:string) "CYP81E1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.89"^^xsd:string) "isoflavone 2'-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.89"^^xsd:string) "CYP Ge-3"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.89"^^xsd:string) "isoflavone,NADPH:oxygen oxidoreductase (2'-hydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.89"^^xsd:string) "Catalysis of the reaction: an isoflavone + NADPH + H+ + O2 = a 2'-hydroxyisoflavone + NADP+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "isoflavone 2'-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.91"^^xsd:string) Annotation( "RHEA:14240"^^xsd:string) "Catalysis of the reaction: 10-deoxysarpagine + H(+) + NADPH + O(2) = H(2)O + NADP(+) + sarpagine."^^xsd:string) AnnotationAssertion(rdfs:label "deoxysarpagine hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.91"^^xsd:string) "10-deoxysarpagine,NADPH:oxygen oxidoreductase (10-hydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.91"^^xsd:string) "DOSH"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phenylacetone monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.92"^^xsd:string) Annotation( "RHEA:10127"^^xsd:string) "Catalysis of the reaction: H(+) + NADPH + O(2) + phenylacetone = benzyl acetate + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.92"^^xsd:string) "PAMO"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.92"^^xsd:string) "phenylacetone,NADPH:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.94"^^xsd:string) "CYP3A10"^^xsd:string) AnnotationAssertion(rdfs:label "lithocholate 6beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.94"^^xsd:string) "lithocholate 6beta-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.94"^^xsd:string) "lithocholate,NADPH:oxygen oxidoreductase (6beta-hydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.94"^^xsd:string) Annotation( "RHEA:18860"^^xsd:string) "Catalysis of the reaction: H(+) + lithocholate + NADPH + O(2) = 6-beta-hydroxylithocholate + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.94"^^xsd:string) "6beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.94"^^xsd:string) "cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.95"^^xsd:string) "CYP12"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.95"^^xsd:string) Annotation( "RHEA:10507"^^xsd:string) "Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + H(+) + NADPH + O(2) = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.95"^^xsd:string) "7alpha-hydroxycholest-4-en-3-one,NADPH:oxygen oxidoreductase (12alpha-hydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.95"^^xsd:string) "7alpha-hydroxy-4-cholesten-3-one 12alpha-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.95"^^xsd:string) "sterol 12alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.95"^^xsd:string) "HCO 12alpha-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.96"^^xsd:string) Annotation( "RHEA:15264"^^xsd:string) "Catalysis of the reaction: 5beta-cholestane-3alpha,7alpha-diol + H(+) + NADPH + O(2) = 5beta-cholestane-3alpha,7alpha,12alpha-triol + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.96"^^xsd:string) "5beta-cholestane-3alpha,7alpha-diol,NADPH:oxygen oxidoreductase (12alpha-hydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.96"^^xsd:string) "cytochrome P450 8B1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.96"^^xsd:string) "5beta-cholestane-3alpha,7alpha-diol 12alpha-monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.96"^^xsd:string) "CYP8B1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.96"^^xsd:string) "sterol 12alpha-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.97"^^xsd:string) "taurochenodeoxycholate 6alpha-monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "taurochenodeoxycholate 6alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.97"^^xsd:string) "CYP4A21"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.97"^^xsd:string) "Catalysis of the reactions: taurochenodeoxycholate + NADPH + H+ + O2 = taurohyocholate + NADP+ + H2O, and lithocholate + NADPH + H+ + O2 = hyodeoxycholate + NADP+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.97"^^xsd:string) "taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.97"^^xsd:string) "CYP3A4"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.98"^^xsd:string) "CYP46A1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.98"^^xsd:string) "cytochrome P450 46A1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.98"^^xsd:string) "CYP46"^^xsd:string) AnnotationAssertion(rdfs:label "cholesterol 24-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.98"^^xsd:string) "cholesterol 24-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.98"^^xsd:string) "cholesterol 24S-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.98"^^xsd:string) Annotation( "RHEA:22719"^^xsd:string) "Catalysis of the reaction: cholesterol + H(+) + NADPH + O(2) = (24S)-24-hydroxycholesterol + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.98"^^xsd:string) "cholesterol,NADPH:oxygen oxidoreductase (24-hydroxylating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.99"^^xsd:string) "24-hydroxycholesterol 7alpha-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.99"^^xsd:string) "(24R)-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "24-hydroxycholesterol 7alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.99"^^xsd:string) "CYP39A1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.99"^^xsd:string) Annotation( "RHEA:16096"^^xsd:string) "Catalysis of the reaction: (24R)-cholest-5-ene-3beta,24-diol + H(+) + NADPH + O(2) = (24R)-7alpha,24-dihydroxycholesterol + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.99"^^xsd:string) "CYP39A1 oxysterol 7alpha-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.100"^^xsd:string) "Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.100"^^xsd:string) "cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "25-hydroxycholesterol 7alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.100"^^xsd:string) "CYP7B1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.100"^^xsd:string) "CYP7B1 oxysterol 7alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.100"^^xsd:string) "25-hydroxycholesterol 7alpha-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.101"^^xsd:string) Annotation( "RHEA:11423"^^xsd:string) "Catalysis of the reaction: H(+) + NADPH + O(2) + senecionine = H(2)O + NADP(+) + senecionine N-oxide."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.101"^^xsd:string) "senecionine monooxygenase (N-oxide-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "senecionine N-oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.101"^^xsd:string) "senecionine,NADPH:oxygen oxidoreductase (N-oxide-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.101"^^xsd:string) "SNO"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "D-alpha,beta-D-heptose 7-phosphate 1-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-4341"^^xsd:string) "Catalysis of the reaction: D-alpha,beta-D-heptose-7-phosphate + ATP = D-beta-D-heptose-1,7-bisphosphate + ADP."^^xsd:string) AnnotationAssertion(rdfs:label "heptose 7-phosphate kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "heptose 1-phosphate adenyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "heptose-1-phosphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion( "D-beta-D-heptose 1-phosphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-4342"^^xsd:string) "Catalysis of the reaction: D-beta-D-heptose-1-phosphate + ATP = ADP-D-glycero-D-manno-heptose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.16.1.6"^^xsd:string) "cyanocobalamin reductase (NADPH, cyanide-eliminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.6"^^xsd:string) Annotation( "RHEA:16116"^^xsd:string) "Catalysis of the reaction: cob(I)alamin + hydrogen cyanide + NADP(+) = cyanocob(III)alamin + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.6"^^xsd:string) "NADPH2:cyanocob(III)alamin oxidoreductase (cyanide-eliminating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyanocobalamin reductase (cyanide-eliminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.6"^^xsd:string) "cyanocobalamin reductase (NADPH; CN-eliminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.6"^^xsd:string) "cob(I)alamin, cyanide:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.6"^^xsd:string) "NADPH:cyanocob(III)alamin oxidoreductase (cyanide-eliminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.6"^^xsd:string) "cyanocobalamin reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.17.1.3"^^xsd:string) "Catalysis of the reaction: (2R,3S)-catechin + NADP+ + H2O = 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.3"^^xsd:string) "leucocyanidin reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "leucoanthocyanidin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.3"^^xsd:string) "(2R,3S)-catechin:NADP+ 4-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.17.5.1"^^xsd:string) "phenylacetyl-CoA:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.5.1"^^xsd:string) Annotation( "RHEA:15708"^^xsd:string) "Catalysis of the reaction: 2 1,4-benzoquinone + H(2)O + phenylacetyl-CoA = 2 hydroquinone + phenylglyoxylyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.5.1"^^xsd:string) "phenylacetyl-CoA:quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phenylacetyl-CoA dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroxymethylfurfural reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jp"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:15338422"^^xsd:string) Annotation( "PMID:16652391"^^xsd:string) "Catalysis of the reaction: 5-hydroxymethylfurfural + NAD(P)H + H+ = 2,5-bis-hydroxymethylfuran + NAD(P)+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.99.3"^^xsd:string) "trihydroxycoprostanoyl-CoA oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.99.3"^^xsd:string) "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate 24-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.99.3"^^xsd:string) "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.99.3"^^xsd:string) "Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.99.3"^^xsd:string) "THC-CoA oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.99.3"^^xsd:string) "(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA:acceptor 24-oxidoreductase (24R-hydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.99.3"^^xsd:string) "THCA-CoA oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.17.99.5"^^xsd:string) "bile acid 7-dehydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.99.5"^^xsd:string) "deoxycholate:FAD oxidoreductase (7alpha-dehydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.99.5"^^xsd:string) "deoxycholate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "bile-acid 7alpha-dehydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.99.5"^^xsd:string) "cholate 7alpha-dehydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.99.5"^^xsd:string) "Catalysis of the reactions: deoxycholate + FAD + H2O = cholate + FADH2, and lithocholate + FAD + H2O = chenodeoxycholate + FADH2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.99.5"^^xsd:string) "7alpha-dehydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.21.3.6"^^xsd:string) "Catalysis of the reactions: 2',4,4',6'-tetrahydroxychalcone + O2 = aureusidin + H2O, and 2',3,4,4',6'-pentahydroxychalcone + 1/2 O2 = aureusidin + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.3.6"^^xsd:string) "2',4,4',6'-tetrahydroxychalcone:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aureusidin synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.21.4.3"^^xsd:string) "Catalysis of the reaction: acetyl phosphate + methylamine + thioredoxin disulfide = N-methylglycine + phosphate + thioredoxin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.4.3"^^xsd:string) "acetyl-phosphate methylamine:thioredoxin disulfide oxidoreductase (N-methylglycine-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "sarcosine reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "betaine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.4.4"^^xsd:string) "acetyl-phosphate trimethylamine:thioredoxin disulfide oxidoreductase (N,N,N-trimethylglycine-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.4.4"^^xsd:string) "Catalysis of the reaction: acetyl phosphate + trimethylamine + thioredoxin disulfide = N,N,N-trimethylglycine + phosphate + thioredoxin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sulfur reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.3"^^xsd:string) "Catalysis of the reduction of elemental sulfur or polysulfide to hydrogen sulfide."^^xsd:string) AnnotationAssertion( "sulphur reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.3"^^xsd:string) "(donor):sulfur oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.97.1.9"^^xsd:string) "selenite:reduced acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.9"^^xsd:string) Annotation( "RHEA:14031"^^xsd:string) "Catalysis of the reaction: 2 e(-) + 2 H(+) + selenate = H(2)O + selenite."^^xsd:string) AnnotationAssertion(rdfs:label "selenate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thyroxine 5-deiodinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.11"^^xsd:string) "type III iodothyronine deiodinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.11"^^xsd:string) "diiodothyronine 5'-deiodinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.11"^^xsd:string) "iodothyronine 5-deiodinase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:20403357"^^xsd:string) "inner ring-deiodinating pathway"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.11"^^xsd:string) "acceptor:3,3',5'-triiodo-L-thyronine oxidoreductase (iodinating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.11"^^xsd:string) "iodothyronine inner ring monodeiodinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.11"^^xsd:string) "Catalysis of the reaction: 3,3',5'-triiodo-L-thyronine + iodide + A + H+ = L-thyroxine + AH2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.149"^^xsd:string) "S-adenosyl-L-methionine:myricetin O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "myricetin 3'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.149"^^xsd:string) "flavonoid 3',5'-O-dimethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.149"^^xsd:string) "CrCOMT2"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8451"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "isoflavone 7-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.150"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 7-methoxyisoflavone."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.150"^^xsd:string) "S-adenosyl-L-methionine:hydroxyisoflavone 7-O-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.153"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside = S-adenosyl-L-homocysteine + 7-O-methylvitexin 2''-O-beta-L-rhamnoside."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.153"^^xsd:string) "S-adenosyl-L-methionine:vitexin-2''-O-beta-L-rhamnoside 7-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "vitexin 2''-O-rhamnoside 7-O-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.154"^^xsd:string) Annotation( "RHEA:21611"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + isoliquiritigenin = 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.154"^^xsd:string) "S-adenosyl-L-methionine:isoliquiritigenin 2'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "isoliquiritigenin 2'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.154"^^xsd:string) "chalcone OMT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.154"^^xsd:string) "CHMT"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.155"^^xsd:string) "S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.155"^^xsd:string) Annotation( "RHEA:15108"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + kaempferol = S-adenosyl-L-homocysteine + H(+) + kaempferide."^^xsd:string) AnnotationAssertion(rdfs:label "kaempferol 4'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.155"^^xsd:string) "F 4'-OMT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.155"^^xsd:string) "S-adenosyl-L-methionine:kaempferol 4'-O-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.2.1.8"^^xsd:string) "Catalysis of the reaction: L-threonine + fluoroacetaldehyde = acetaldehyde + 4-fluoro-L-threonine."^^xsd:string) AnnotationAssertion(rdfs:label "fluorothreonine transaldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.8"^^xsd:string) "fluoroacetaldehyde:L-threonine aldehydetransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.119"^^xsd:string) "stearoyl-CoA elongase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.119"^^xsd:string) "acyl-CoA elongase activity"^^xsd:string) AnnotationAssertion(rdfs:label "icosanoyl-CoA synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.119"^^xsd:string) "stearoyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.119"^^xsd:string) "Catalysis of the reaction: stearoyl-CoA + malonyl-CoA + 2 NAD(P)H + 2 H+ = icosanoyl-CoA + CO2 + 2 NAD(P)+."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.119"^^xsd:string) "C18-CoA elongase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.170"^^xsd:string) "Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA + NADPH + H+ = 4 CoA + isoliquiritigenin + 3 CO2 + NADP+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.170"^^xsd:string) "malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing, reducing) activity"^^xsd:string) AnnotationAssertion(rdfs:label "6'-deoxychalcone synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.171"^^xsd:string) "3MaT"^^xsd:string) AnnotationAssertion(rdfs:label "anthocyanin 6''-O-malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.171"^^xsd:string) "Catalysis of the reaction: malonyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = CoA + an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.171"^^xsd:string) "malonyl-coenzymeA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.171"^^xsd:string) "Dv3MaT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.171"^^xsd:string) "malonyl-CoA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "anthocyanin 5-O-glucoside 6'''-O-malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.172"^^xsd:string) "Catalysis of the reaction: malonyl-CoA + pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside = CoA + 4'''-demalonylsalvianin."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.172"^^xsd:string) "malonyl-CoA:pelargonidin-3-O-(6-caffeoyl-beta-D-glucoside)-5-O-beta-D-glucoside 6'''-O-malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.172"^^xsd:string) "Ss5MaT1"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "flavonol-3-O-triglucoside O-coumaroyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.173"^^xsd:string) "Catalysis of the reaction: 4-coumaroyl-CoA + a flavonol 3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] = CoA + a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside]."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.173"^^xsd:string) "4-coumaroyl-CoA:flavonol-3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] 6'''-O-4-coumaroyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.174"^^xsd:string) "Catalysis of the reaction: succinyl-CoA + acetyl-CoA = CoA + 3-oxoadipyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.174"^^xsd:string) "succinyl-CoA:acetyl-CoA C-succinyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-oxoadipyl-CoA thiolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.175"^^xsd:string) "acetyl coenzyme A:DAC acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.175"^^xsd:string) "deacetylcephalosporin C acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.175"^^xsd:string) "acetyl-CoA:deacetylcephalosporin-C O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.175"^^xsd:string) "acetyl-CoA:DAC acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.175"^^xsd:string) "DAC-AT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.175"^^xsd:string) "cefG"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.175"^^xsd:string) "acetyl-CoA:DAC O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.175"^^xsd:string) "CPC acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.175"^^xsd:string) "acetyl-CoA:deacetylcephalosporin-C acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "deacetylcephalosporin-C acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.175"^^xsd:string) "DAC acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.175"^^xsd:string) Annotation( "RHEA:23863"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + deacetylcephalosporin C = cephalosporin C + CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.176"^^xsd:string) "Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.176"^^xsd:string) "sterol carrier protein-chi"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.176"^^xsd:string) "PTE-2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.176"^^xsd:string) "SCP-X"^^xsd:string) AnnotationAssertion(rdfs:label "propanoyl-CoA C-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.176"^^xsd:string) "SCPchi"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.176"^^xsd:string) "peroxisomal thiolase 2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.176"^^xsd:string) "sterol carrier protein-X"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.176"^^xsd:string) "3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "biphenyl synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.177"^^xsd:string) "Catalysis of the reaction: 3 malonyl-CoA + benzoyl-CoA = 4 CoA + 3,5-dihydroxybiphenyl + 4 CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.177"^^xsd:string) "BIS"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.177"^^xsd:string) "malonyl-CoA:benzoyl-CoA malonyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.178"^^xsd:string) "DAB acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.178"^^xsd:string) "L-2,4-diaminobutyrate acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.178"^^xsd:string) "DABA acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.178"^^xsd:string) "diaminobutyric acid acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.178"^^xsd:string) Annotation( "RHEA:16904"^^xsd:string) "Catalysis of the reaction: L-2,4-diaminobutyrate + acetyl-CoA = N(4)-acetyl-L-2,4-diaminobutyrate + CoA + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "diaminobutyrate acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.178"^^xsd:string) "acetyl-CoA:L-2,4-diaminobutanoate N4-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.178"^^xsd:string) "EctA"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.178"^^xsd:string) "2,4-diaminobutanoate acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.178"^^xsd:string) "L-2,4-diaminobutanoate acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.178"^^xsd:string) "acetyl-CoA:L-2,4-diaminobutanoate 4-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.178"^^xsd:string) "DABAcT"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.179"^^xsd:string) "(Z)-hexadec-11-enoyl-acyl-carrier-protein:malonyl-acyl-carrier-protein C-acyltransferase (decarboxylating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-ketoacyl-acyl-carrier-protein synthase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.179"^^xsd:string) "beta-ketoacyl-ACP synthase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.179"^^xsd:string) "Catalysis of the reaction: (Z)-hexadec-11-enoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.179"^^xsd:string) "KASII"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.179"^^xsd:string) "KAS II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.179"^^xsd:string) "3-oxoacyl-acyl carrier protein synthase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.179"^^xsd:string) "FabF"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.180"^^xsd:string) "beta-ketoacyl-acyl carrier protein synthase III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.180"^^xsd:string) "beta-ketoacyl (acyl carrier protein) synthase III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.180"^^xsd:string) "beta-ketoacyl-ACP synthase III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.180"^^xsd:string) "KASIII"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.180"^^xsd:string) "FabH"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.180"^^xsd:string) "3-oxoacyl:ACP synthase III activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-ketoacyl-acyl-carrier-protein synthase III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.180"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + malonyl-[acyl-carrier protein] = acetoacyl-[acyl-carrier protein] + CoA + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.180"^^xsd:string) "3-ketoacyl-acyl carrier protein synthase III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.180"^^xsd:string) "acetyl-CoA:malonyl-acyl-carrier-protein C-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.180"^^xsd:string) "KAS III"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.181"^^xsd:string) "Catalysis of the reaction: octanoyl-[acyl-carrier protein] + protein = protein N6-(octanoyl)lysine + acyl-carrier protein."^^xsd:string) AnnotationAssertion(rdfs:label "lipoyl(octanoyl) transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.181"^^xsd:string) "lipoate/octanoate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.181"^^xsd:string) "octanoyl-acyl carrier protein-protein N-octanoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.181"^^xsd:string) "octanoyl-acyl-carrier-protein:protein N-octanoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.181"^^xsd:string) "LipB"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.181"^^xsd:string) "lipoyl (octanoyl)-acyl carrier protein:protein transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.181"^^xsd:string) "lipoyl (octanoyl)-acyl-carrier-protein-protein N-lipoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.181"^^xsd:string) "octanoyl-acyl-carrier-protein-protein N-octanoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.26"^^xsd:string) "T6-HMC-alpha-glucosyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.26"^^xsd:string) "UDP-glucose:DNA alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.26"^^xsd:string) "Catalysis of the transfer of an alpha-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA."^^xsd:string) AnnotationAssertion(rdfs:label "DNA alpha-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.26"^^xsd:string) "T4-HMC-alpha-glucosyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.26"^^xsd:string) "UDPglucose-DNA alpha-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.26"^^xsd:string) "uridine diphosphoglucose-deoxyribonucleate alpha-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.26"^^xsd:string) "T2-HMC-alpha-glucosyl transferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.27"^^xsd:string) "uridine diphosphoglucose-deoxyribonucleate beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.27"^^xsd:string) "UDP glucose-DNA beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.27"^^xsd:string) "Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.27"^^xsd:string) "UDPglucose:DNA beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.27"^^xsd:string) "T4-beta-glucosyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.27"^^xsd:string) "UDP-glucose:DNA beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.27"^^xsd:string) "T4 phage beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.27"^^xsd:string) "T4-HMC-beta-glucosyl transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "DNA beta-glucosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.28"^^xsd:string) "uridine diphosphoglucose-glucosyldeoxyribonucleate beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.28"^^xsd:string) "UDPglucose:D-glucosyl-DNA beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucosyl-DNA beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.28"^^xsd:string) "UDP-glucose:D-glucosyl-DNA beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.28"^^xsd:string) "T6-beta-glucosyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.28"^^xsd:string) "Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a glucosylhydroxymethylcytosine residue in DNA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.28"^^xsd:string) "T6-glucosyl-HMC-beta-glucosyl transferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.66"^^xsd:string) "galactosylhydroxylysyl glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.66"^^xsd:string) "UDP-glucose:5-(D-galactosyloxy)-L-lysine-procollagen D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "procollagen glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.66"^^xsd:string) "galactosylhydroxylysine glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.66"^^xsd:string) "collagen glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.66"^^xsd:string) "galactosylhydroxylysine-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.66"^^xsd:string) "Catalysis of the reaction: UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen = UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.66"^^xsd:string) "uridine diphosphoglucose-collagen glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.66"^^xsd:string) "collagen hydroxylysyl glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.66"^^xsd:string) "UDPglucose:5-(D-galactosyloxy)-L-lysine-procollagen D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.66"^^xsd:string) "UDP-glucose-collagenglucosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.140"^^xsd:string) "sucrose:1,6(1,3)-alpha-D-glucan 6(3)-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.140"^^xsd:string) "sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and 6-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alternansucrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.140"^^xsd:string) "sucrose-1,6(3)-alpha-glucan 6(3)-alpha-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.140"^^xsd:string) "Catalysis of the transfer of an alpha-D-glucosyl residue from sucrose to alternately the 6-position and the 3-position of the non-reducing terminal residue of an alpha-D-glucan, thus producing a glucan having alternating alpha-1,6- and alpha-1,3-linkages."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.161"^^xsd:string) "amylase III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.161"^^xsd:string) "1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oligosaccharide 4-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.161"^^xsd:string) "Catalysis of the transfer of the non-reducing terminal alpha-D-glucose residue from a 1,4-alpha-D-glucan to the 4-position of an alpha-D-glucan, thus bringing about the hydrolysis of oligosaccharides."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.161"^^xsd:string) "1,4-alpha-glucan:1,4-alpha-glucan 4-alpha-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.168"^^xsd:string) "UDPglucose:xyloglucan 1,4-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.168"^^xsd:string) "UDP-glucose:xyloglucan 1,4-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.168"^^xsd:string) "uridine diphosphoglucose-xyloglucan 4beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.168"^^xsd:string) "xyloglucan 4beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.168"^^xsd:string) "xyloglucan glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.168"^^xsd:string) "Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose on to a glucose residue in xyloglucan, forming a beta-1,4-D-glucosyl-D-glucose linkage."^^xsd:string) AnnotationAssertion(rdfs:label "xyloglucan 4-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.197"^^xsd:string) "Catalysis of the transfer of an N-acetyl-D-glucosamine residue from UDP-N-acetyl-D-glucosamine to the 4-position of a mannose linked alpha-1,6 to the core mannose of high-mannose oligosaccharides produced by Dictyostelium discoideum."^^xsd:string) AnnotationAssertion(rdfs:label "high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.197"^^xsd:string) "uridine diphosphoacetylglucosamine-oligosaccharide acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.197"^^xsd:string) "UDP-GlcNAc:oligosaccharide beta-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.197"^^xsd:string) "acetylglucosamine-oligosaccharide acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.197"^^xsd:string) "UDP-N-acetyl-D-glucosamine:high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.213"^^xsd:string) "glucosyl-glycerol-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.213"^^xsd:string) "GG-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.213"^^xsd:string) "GGPS"^^xsd:string) AnnotationAssertion(rdfs:label "glucosylglycerol-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.213"^^xsd:string) "ADP-glucose:sn-glycerol-3-phosphate 2-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.213"^^xsd:string) Annotation( "RHEA:12884"^^xsd:string) "Catalysis of the reaction: sn-glycerol 3-phosphate + ADP-glucose = 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + ADP + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.213"^^xsd:string) "ADPglucose:sn-glycerol-3-phosphate 2-beta-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.222"^^xsd:string) "O-fucosylpeptide beta-1,3-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.222"^^xsd:string) "Catalysis of the transfer of a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.222"^^xsd:string) "UDP-D-GlcNAc:O-L-fucosylpeptide 3-beta-N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.229"^^xsd:string) "UDP-N-acetyl-D-glucosamine:Skp1-protein-hydroxyproline N-acetyl-D-glucosaminyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.229"^^xsd:string) "Catalysis of the reaction: UDP-N-acetylglucosamine + Skp1-protein-hydroxyproline = UDP + Skp1-protein-O-(N-acetyl-D-glucosaminyl)hydroxyproline."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.229"^^xsd:string) "UDP-GlcNAc:Skp1-hydroxyproline GlcNAc-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.229"^^xsd:string) "Skp1-HyPro GlcNAc-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.229"^^xsd:string) "UDP-GlcNAc:hydroxyproline polypeptide GlcNAc-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.229"^^xsd:string) "UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.230"^^xsd:string) Annotation( "RHEA:11179"^^xsd:string) "Catalysis of the reaction: kojibiose + phosphate = beta-D-glucose 1-phosphate + D-glucose."^^xsd:string) AnnotationAssertion(rdfs:label "kojibiose phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.230"^^xsd:string) "2-alpha-D-glucosyl-D-glucose:phosphate beta-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha,alpha-trehalose phosphorylase (configuration-retaining) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.231"^^xsd:string) "trehalose phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.231"^^xsd:string) "Catalysis of the reaction: alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.231"^^xsd:string) "alpha,alpha-trehalose:phosphate alpha-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jp"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:15338422"^^xsd:string) Annotation( "PMID:16652391"^^xsd:string) "Catalysis of the reaction: 5-hydroxymethylfurfural + NADH + H+ = 2,5-bis-hydroxymethylfuran + NAD+."^^xsd:string) AnnotationAssertion(rdfs:label "hydroxymethylfurfural reductase (NADH) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.234"^^xsd:string) "Catalysis of the reaction: UDP-galactose + kaempferol = UDP + kaempferol 3-O-beta-D-galactoside."^^xsd:string) AnnotationAssertion(rdfs:label "kaempferol 3-O-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.234"^^xsd:string) "UDP-galactose:kaempferol 3-O-beta-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.234"^^xsd:string) "F3GalTase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.236"^^xsd:string) "Catalysis of the reaction: UDP-L-rhamnose + a flavanone 7-O-glucoside = UDP + a flavanone 7-O-[beta-L-rhamnosyl-(1->2)-beta-D-glucoside]."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.236"^^xsd:string) "1->2 UDP-rhamnosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.236"^^xsd:string) "UDP-rhamnose:flavanone-7-O-glucoside-2''-O-rhamnosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.236"^^xsd:string) "UDP-L-rhamnose:flavanone-7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.237"^^xsd:string) "UDP-glucose:flavonol 7-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "flavonol 7-O-beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.237"^^xsd:string) "UDP-glucose:flavonol 7-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.237"^^xsd:string) "Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 7-O-beta-D-glucoside."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.238"^^xsd:string) "UDP-glucose:anthocyanin 3'-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.238"^^xsd:string) "Catalysis of the reaction: UDP-glucose + an anthocyanin = UDP + an anthocyanin 3'-O-beta-D-glucoside."^^xsd:string) AnnotationAssertion(rdfs:label "anthocyanin 3'-O-beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.238"^^xsd:string) "UDP-glucose:anthocyanin 3'-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.238"^^xsd:string) "3'GT"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.239"^^xsd:string) "UDP-glucose:flavonol-3-O-glucoside 2''-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "flavonol-3-O-glucoside glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.239"^^xsd:string) "Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.240"^^xsd:string) "Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.240"^^xsd:string) "UDP-glucose:flavonol-3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 2'''-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "flavonol-3-O-glycoside glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.242"^^xsd:string) "waxy protein"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.242"^^xsd:string) "starch synthase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.242"^^xsd:string) "granule-bound starch synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.242"^^xsd:string) "GBSS"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.242"^^xsd:string) "starch granule-bound nucleoside diphosphate glucose-starch glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.242"^^xsd:string) "NDPglucose-starch glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.242"^^xsd:string) "Catalysis of the reaction: NDP-glucose + (1,4-alpha-D-glucosyl)n = NDP + (1,4-alpha-D-glucosyl)n+1."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.242"^^xsd:string) "granule-bound starch synthase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.242"^^xsd:string) "NDP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.242"^^xsd:string) "GBSSI"^^xsd:string) AnnotationAssertion(rdfs:label "NDP-glucose-starch glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.242"^^xsd:string) "GBSSII"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.242"^^xsd:string) "granule-bound starch synthase I activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.243"^^xsd:string) "Catalysis of the reaction: [1-beta-D-fructofuranosyl-(2->1)-]m+1 alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 alpha-D-glucopyranoside = [1-beta-D-fructofuranosyl-(2->1)-]m alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 beta-D-fructofuranosyl-(2->6)-alpha-D-glucopyranoside (m > 0; n >= 0)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.243"^^xsd:string) "1F-oligo[beta-D-fructofuranosyl-(2->1)-]sucrose 6G-beta-D-fructotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.243"^^xsd:string) "fructan:fructan 6G-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.243"^^xsd:string) "6G-fructotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.243"^^xsd:string) "6G-FFT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.243"^^xsd:string) "6G-FT"^^xsd:string) AnnotationAssertion(rdfs:label "6G-fructosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.244"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + N-acetyl-beta-D-glucosaminyl group = UDP + N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl group."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.244"^^xsd:string) "beta1,4-N-acetylgalactosaminyltransferase IV activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.244"^^xsd:string) "beta4GalNAc-T3"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.244"^^xsd:string) "beta1,4-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.244"^^xsd:string) "UDP-N-acetyl-D-galactosamine:N-acetyl-D-glucosaminyl-group beta-1,4-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.244"^^xsd:string) "beta1,4-N-acetylgalactosaminyltransferase III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.244"^^xsd:string) "beta4GalNAc-T4"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "xyloglucan 6-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.39"^^xsd:string) "xyloglucan 6-alpha-D-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.39"^^xsd:string) "Catalysis of the transfer of an alpha-D-xylosyl residue from UDP-D-xylose to a glucose residue in xyloglucan, forming an alpha-1,6-D-xylosyl-D-glucose linkage."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.39"^^xsd:string) "UDP-D-xylose:xyloglucan 1,6-alpha-D-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.39"^^xsd:string) "uridine diphosphoxylose-xyloglucan 6alpha-xylosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.5"^^xsd:string) "galactose 6-sulfatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactose-6-sulfurylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.5"^^xsd:string) "D-galactose-6-sulfate:alkyltransferase (cyclizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.5"^^xsd:string) "porphyran sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.5"^^xsd:string) "Catalysis of the elimination of sulfate from the D-galactose 6-sulfate residues of porphyran, producing 3,6-anhydrogalactose residues."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.5"^^xsd:string) "galactose-6-sulfatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroxymethylfurfural reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jp"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:15338422"^^xsd:string) Annotation( "PMID:16652391"^^xsd:string) "Catalysis of the reaction: 5-hydroxymethylfurfural + NADPH + H+ = 2,5-bis-hydroxymethylfuran + NADP+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.63"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.63"^^xsd:string) "S-adenosyl-L-methionine:fluoride adenosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.63"^^xsd:string) "fluorinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "adenosyl-fluoride synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.65"^^xsd:string) "Catalysis of the reaction: O-phospho-L-serine + hydrogen sulfide = L-cysteine + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.65"^^xsd:string) "O-phospho-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.65"^^xsd:string) "O-phosphoserine(thiol)-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "O-phosphoserine sulfhydrylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.66"^^xsd:string) "CEA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.66"^^xsd:string) "glyceraldehyde-3-phosphate:L-arginine 2-N-(2-hydroxy-3-oxopropyl) transferase (2-carboxyethyl-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.66"^^xsd:string) "glyceraldehyde-3-phosphate:L-arginine N2-(2-hydroxy-3-oxopropyl) transferase (2-carboxyethyl-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "N2-(2-carboxyethyl)arginine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.66"^^xsd:string) Annotation( "RHEA:10559"^^xsd:string) "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + L-arginine = N(2)-(2-carboxyethyl)-L-arginine + H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.66"^^xsd:string) "CEAS"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.66"^^xsd:string) "N2-(2-carboxyethyl)arginine synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chrysanthemyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.67"^^xsd:string) "CPPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.67"^^xsd:string) Annotation( "RHEA:14012"^^xsd:string) "Catalysis of the reaction: 2 dimethylallyl diphosphate = (R,R)-chrysanthemyl diphosphate + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.67"^^xsd:string) "dimethylallyl-diphosphate:dimethylallyl-diphosphate dimethylallyltransferase (chrysanthemyl-diphosphate-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.68"^^xsd:string) Annotation( "RHEA:23303"^^xsd:string) "Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-cis,6-trans-farnesyl diphosphate + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "Z-farnesyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.68"^^xsd:string) "(Z)-farnesyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.68"^^xsd:string) "geranyl-diphosphate:isopentenyl-diphosphate geranylcistransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.69"^^xsd:string) "FDS-5"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.69"^^xsd:string) "dimethylallyl-diphosphate:dimethylallyl-diphosphate dimethylallyltransferase (lavandulyl-diphosphate-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "lavandulyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.69"^^xsd:string) Annotation( "RHEA:21679"^^xsd:string) "Catalysis of the reaction: 2 dimethylallyl diphosphate = diphosphate + lavandulyl diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.26"^^xsd:string) "L-3,5,3'-triiodothyronine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.26"^^xsd:string) "3,5-dinitrotyrosine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.26"^^xsd:string) "thyroid-hormone aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.26"^^xsd:string) "thyroid hormone aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.26"^^xsd:string) "3,5-dinitrotyrosine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.26"^^xsd:string) Annotation( "RHEA:19136"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + 3,5,3'-triiodo-L-thyronine = 3,5,3'-triiodothyropyruvate + L-glutamate."^^xsd:string) AnnotationAssertion(rdfs:label "thyroid-hormone transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.78"^^xsd:string) "L-arogenate:oxaloacetate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.78"^^xsd:string) "PAT"^^xsd:string) AnnotationAssertion(rdfs:label "aspartate-prephenate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.78"^^xsd:string) "prephenate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.78"^^xsd:string) "L-aspartate:prephenate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.78"^^xsd:string) "Catalysis of the reaction: L-arogenate + oxaloacetate = prephenate + L-aspartate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.78"^^xsd:string) "prephenate aspartate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.79"^^xsd:string) Annotation( "RHEA:22883"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + L-arogenate = L-glutamate + prephenate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.79"^^xsd:string) "PAT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.79"^^xsd:string) "L-arogenate:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.79"^^xsd:string) "prephenate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.79"^^xsd:string) "L-glutamate:prephenate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamate-prephenate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.80"^^xsd:string) "NAAT-III"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.80"^^xsd:string) "NAAT-I"^^xsd:string) AnnotationAssertion(rdfs:label "nicotianamine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.80"^^xsd:string) "nicotianamine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.80"^^xsd:string) "nicotianamine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.80"^^xsd:string) "NAAT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.80"^^xsd:string) Annotation( "RHEA:22107"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + nicotianamine = 3''-deamino-3''-oxonicotianamine + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.80"^^xsd:string) "NAAT-II"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.99.2"^^xsd:string) "PdxJ"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.99.2"^^xsd:string) "PNP synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyridoxine 5'-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.99.2"^^xsd:string) Annotation( "RHEA:15268"^^xsd:string) "Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = 2 H(2)O + H(+) + phosphate + pyridoxine 5'-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.99.2"^^xsd:string) "1-deoxy-D-xylulose-5-phosphate:3-amino-2-oxopropyl phosphate 3-amino-2-oxopropyltransferase (phosphate-hydrolysing; cyclizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.99.2"^^xsd:string) "pyridoxine 5-phosphate phospho lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.4.24"^^xsd:string) "PP-InsP5 kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "diphosphoinositol-pentakisphosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.24"^^xsd:string) "ATP:5-diphospho-1D-myo-inositol-pentakisphosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.24"^^xsd:string) "PPIP5K2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.24"^^xsd:string) "VIP1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.24"^^xsd:string) "PPIP5K"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.24"^^xsd:string) "Catalysis of the reaction: ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-inositol bisdiphosphate tetrakisphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.24"^^xsd:string) "PPIP5K1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.24"^^xsd:string) "VIP2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.24"^^xsd:string) "PP-IP5 kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.157"^^xsd:string) "N-acetylgalactosamine (GalNAc)-1-phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.157"^^xsd:string) "Catalysis of the reaction: ATP + N-acetyl-D-galactosamine = ADP + N-acetyl-alpha-D-galactosamine 1-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylgalactosamine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.157"^^xsd:string) "GALK2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.157"^^xsd:string) "GalNAc kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.157"^^xsd:string) "GK2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.157"^^xsd:string) "ATP:N-acetyl-D-galactosamine 1-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.4.22"^^xsd:string) "PyrH"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.22"^^xsd:string) "UMPK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.22"^^xsd:string) "UMP-kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UMP kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.22"^^xsd:string) "uridine monophosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.22"^^xsd:string) "Catalysis of the reaction: ATP + UMP = ADP + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.22"^^xsd:string) "ATP:UMP phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.22"^^xsd:string) "SmbA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.4.23"^^xsd:string) "ribose 1,5-bisphosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.23"^^xsd:string) Annotation( "RHEA:20112"^^xsd:string) "Catalysis of the reaction: D-ribose 1,5-diphosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + ADP + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.23"^^xsd:string) "ATP:ribose-1,5-bisphosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ribose 1,5-bisphosphate phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.23"^^xsd:string) "PhnN"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.8"^^xsd:string) "FAST"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.8"^^xsd:string) "Catalysis of the reaction: ATP + Fas-activated serine/threonine protein = ADP + Fas-activated serine/threonine phosphoprotein."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.8"^^xsd:string) "FASTK"^^xsd:string) AnnotationAssertion(rdfs:label "Fas-activated serine/threonine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.8"^^xsd:string) "STK10"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.8"^^xsd:string) "ATP:Fas-activated serine/threonine protein phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Goodpasture-antigen-binding protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.9"^^xsd:string) "GPBP kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.9"^^xsd:string) "GPBPK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.9"^^xsd:string) "Goodpasture antigen-binding protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.9"^^xsd:string) "STK11"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.9"^^xsd:string) "Catalysis of the reaction: ATP + Goodpasture antigen-binding protein = ADP + Goodpasture antigen-binding phosphoprotein."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.9"^^xsd:string) "ATP:Goodpasture antigen-binding protein phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.16"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + a thiol = adenosine 3',5'-bisphosphate + an S-alkyl thiosulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.16"^^xsd:string) "3'-phosphoadenylyl-sulfate:thiol S-sulfotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiol sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.16"^^xsd:string) "adenosine 3'-phosphate 5'-sulphatophosphate sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.16"^^xsd:string) "PAPS sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "heparin-glucosamine 3-sulfotransferase 2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.29"^^xsd:string) "3-OST-2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.29"^^xsd:string) "glucosaminyl 3-O-sulfotransferase 2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.29"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate; modifies selected glucosamine residues preceded by GlcA2S."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.29"^^xsd:string) "heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.29"^^xsd:string) "glucosaminyl 3-O-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.29"^^xsd:string) "heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.29"^^xsd:string) "isoform/isozyme 2 (3-OST-2, HS3ST2)"^^xsd:string) AnnotationAssertion(rdfs:label "[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.29"^^xsd:string) "3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.30"^^xsd:string) "heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3 activity"^^xsd:string) AnnotationAssertion(rdfs:label "[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.30"^^xsd:string) "isoform/isozyme 3a and 3b (3-OST-3A, 3-OST-3B, HS3ST3A, HS3ST3B)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.30"^^xsd:string) "3-OST-3"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.30"^^xsd:string) "glucosaminyl 3-O-sulfotransferase 3a, 3b activity"^^xsd:string) AnnotationAssertion( "heparin-glucosamine 3-sulfotransferase 3 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.30"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.30"^^xsd:string) "glucosaminyl 3-O-sulfotransferase 3 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.30"^^xsd:string) "3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.30"^^xsd:string) "heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.31"^^xsd:string) Annotation( "RHEA:17000"^^xsd:string) "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol = 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate + adenosine 3',5'-diphosphate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.31"^^xsd:string) "PZ-SULT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.31"^^xsd:string) "3'-phosphoadenylyl-sulfate:5alpha-cholan-3alpha,7alpha,12alpha,24-tetrol sulfotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "petromyzonol sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.32"^^xsd:string) Annotation( "RHEA:15480"^^xsd:string) "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5beta-scymnol = 5beta-scymnol sulfate + adenosine 3',5'-diphosphate + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "scymnol sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycochenodeoxycholate sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.34"^^xsd:string) "3'-phosphoadenylyl-sulfate:glycochenodeoxycholate 7-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.34"^^xsd:string) "BAST"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.34"^^xsd:string) "bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.34"^^xsd:string) Annotation( "RHEA:17692"^^xsd:string) "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + glycochenodeoxycholate = adenosine 3',5'-diphosphate + glycochenodeoxycholate 7-sulfate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.34"^^xsd:string) "bile acid:PAPS:sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "succinyl-CoA:(R)-benzylsuccinate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.15"^^xsd:string) "benzylsuccinate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.15"^^xsd:string) "succinyl-CoA:(R)-2-benzylsuccinate CoA-transferase activity"^^xsd:string) AnnotationAssertion( "succinyl-CoA:benzylsuccinate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.15"^^xsd:string) Annotation( "RHEA:16472"^^xsd:string) "Catalysis of the reaction: (R)-2-benzylsuccinate + succinyl-CoA = (R)-2-benzylsuccinyl-CoA + succinate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.79"^^xsd:string) "HSL"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.79"^^xsd:string) "diacylglycerol acylhydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hormone-sensitive lipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.79"^^xsd:string) "Catalysis of the reactions: diacylglycerol + H2O = monoacylglycerol + a carboxylate; triacylglycerol + H2O = diacylglycerol + a carboxylate; and monoacylglycerol + H2O = glycerol + a carboxylate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acetylajmaline esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.80"^^xsd:string) "acetylajmalan esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.80"^^xsd:string) "2beta(R)-17-O-acetylajmalan:acetylesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.80"^^xsd:string) "AAE"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.80"^^xsd:string) "Catalysis of the reactions: 17-O-acetylajmaline + H2O = ajmaline + acetate, and 17-O-acetylnorajmaline + H2O = norajmaline + acetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.80"^^xsd:string) "17-O-acetylajmaline O-acetylhydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phenylacetyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.25"^^xsd:string) "phenylglyoxylyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.25"^^xsd:string) Annotation( "RHEA:15340"^^xsd:string) "Catalysis of the reaction: H(2)O + phenylglyoxylyl-CoA = CoA + H(+) + phenylglyoxylate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bile-acid-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.26"^^xsd:string) "bile acid-coenzyme A hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.26"^^xsd:string) Annotation( "RHEA:17696"^^xsd:string) "Catalysis of the reaction: deoxycholoyl-CoA + H(2)O = CoA + deoxycholate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.26"^^xsd:string) "deoxycholoyl-CoA hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.2.27"^^xsd:string) "chenodeoxycholoyl-coenzyme A thioesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.27"^^xsd:string) "peroxisomal acyl-CoA thioesterase 2 activity"^^xsd:string) AnnotationAssertion(rdfs:label "choloyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.27"^^xsd:string) "PTE-2"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.27"^^xsd:string) "choloyl-coenzyme A thioesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.27"^^xsd:string) "Catalysis of the reaction: choloyl-CoA + H2O = cholate + CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.74"^^xsd:string) "vitamin B6 (pyridoxine) phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.74"^^xsd:string) "Catalysis of the reaction: pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.74"^^xsd:string) "vitamin B6-phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyridoxal phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.74"^^xsd:string) "pyridoxal-5'-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.74"^^xsd:string) "PNP phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.74"^^xsd:string) "PLP phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.76"^^xsd:string) "(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.76"^^xsd:string) "hydroxy fatty acid phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.76"^^xsd:string) Annotation( "RHEA:16540"^^xsd:string) "Catalysis of the reaction: (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H(2)O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.76"^^xsd:string) "dihydroxy fatty acid phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.76"^^xsd:string) "sEH"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.76"^^xsd:string) Annotation( ) "(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.76"^^xsd:string) "hydroxy lipid phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.76"^^xsd:string) "soluble epoxide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.76"^^xsd:string) "lipid-phosphate phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.6.7"^^xsd:string) "cellulose-sulfate sulfohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cellulose-polysulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.7"^^xsd:string) "Catalysis of the hydrolysis of the 2- and 3-sulfate groups of the polysulfates of cellulose and charonin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chondro-4-sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.9"^^xsd:string) Annotation( "RHEA:11447"^^xsd:string) "Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 4-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.9"^^xsd:string) "4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.6.10"^^xsd:string) Annotation( "RHEA:10539"^^xsd:string) "Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.10"^^xsd:string) "4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "chondro-6-sulfatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.6.15"^^xsd:string) "chondroitinsulfatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-sulfoglucosamine-3-sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.15"^^xsd:string) "Catalysis of the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.15"^^xsd:string) "N-sulfo-3-sulfoglucosamine 3-sulfohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.13.5"^^xsd:string) "Catalysis of the exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides."^^xsd:string) AnnotationAssertion(rdfs:label "ribonuclease D activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.13.5"^^xsd:string) "RNase D activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.21.6"^^xsd:string) "5'-CC-3'-preferring endodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.6"^^xsd:string) "Streptomyces glaucescens exocytoplasmic dodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(rdfs:label "CC-preferring endodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.6"^^xsd:string) "Streptomyces glaucescens exocytoplasmic endodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.6"^^xsd:string) "Catalysis of the endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.6"^^xsd:string) "Streptomyces glaucescens exocytoplasmic endonuclease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.25.1"^^xsd:string) "bacteriophage T4 endodeoxyribonuclease V activity"^^xsd:string) AnnotationAssertion(rdfs:label "deoxyribonuclease (pyrimidine dimer) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.25.1"^^xsd:string) "endodeoxyribonuclease (pyrimidine dimer) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.25.1"^^xsd:string) "T4 endonuclease V activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.25.1"^^xsd:string) "Catalysis of the endonucleolytic cleavage near pyrimidine dimers to products with 5'-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ribonuclease IV activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.6"^^xsd:string) "Catalysis of the endonucleolytic cleavage of poly(A) to fragments terminated by 3'-hydroxy and 5'-phosphate groups."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.6"^^xsd:string) "endoribonuclease IV activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ribonuclease P4 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.7"^^xsd:string) "Catalysis of the endonucleolytic cleavage of RNA, removing 3'-extranucleotides from tRNA precursor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.26.9"^^xsd:string) "uracil-specific RNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.9"^^xsd:string) "ribonuclease (uracil-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.9"^^xsd:string) "Catalysis of the endonucleolytic cleavage of poly(U) to fragments terminated by 3'-hydroxy and 5'-phosphate groups."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.9"^^xsd:string) "uracil-specific endoribonuclease activity"^^xsd:string) AnnotationAssertion(rdfs:label "ribonuclease [poly-(U)-specific] activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ribonuclease IX activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.10"^^xsd:string) "Catalysis of the endonucleolytic cleavage of poly(U) or poly(C) to fragments terminated by 3'-hydroxy and 5'-phosphate groups."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.10"^^xsd:string) "poly(U)- and poly(C)-specific endoribonuclease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "ribonucleate nucleotido-2'-transferase (cyclizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "RNase Ms activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "ribonucleate 3'-oligonucleotide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "ribonuclease U4 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "Escherichia coli ribonuclease I' ribonuclease PP2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "Escherichia coli ribonuclease II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "ribonuclease N2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "acid ribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "ribonuclease (non-base specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "base-non-specific ribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "ribonuclease II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "nonbase-specific RNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "ribonuclease M activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "RNase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "ribonnuclease (non-base specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "RNase M activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "non-base specific ribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "acid RNase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ribonuclease T2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "RNase (non-base specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "ribonuclease PP3 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "RNAase CL activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "nonspecific RNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.1"^^xsd:string) "RNase T2 activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.27.2"^^xsd:string) "proteus mirabilis RNase activity"^^xsd:string) AnnotationAssertion(rdfs:label "Bacillus subtilis ribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.2"^^xsd:string) "Catalysis of the endonucleolytic cleavage to 2',3'-cyclic nucleotides."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.2"^^xsd:string) "ribonucleate nucleotido-2'-transferase (cyclizing) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.27.4"^^xsd:string) "purine-specific ribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.4"^^xsd:string) "pleospora RNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.4"^^xsd:string) "ribonuclease (purine) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.4"^^xsd:string) "purine-specific RNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.4"^^xsd:string) "ribonuclease U3 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.4"^^xsd:string) "trichoderma koningi RNase III activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.4"^^xsd:string) "purine specific endoribonuclease activity"^^xsd:string) AnnotationAssertion(rdfs:label "ribonuclease U2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.4"^^xsd:string) "Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.4"^^xsd:string) "RNase U3 activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.27.7"^^xsd:string) "ribonuclease F (E. coli) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.7"^^xsd:string) "Catalysis of the endonucleolytic cleavage of RNA precursor into two, leaving 5'-hydroxy and 3'-phosphate groups."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.7"^^xsd:string) "RNase F activity"^^xsd:string) AnnotationAssertion(rdfs:label "ribonuclease F activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.27.8"^^xsd:string) "endoribonuclease V activity"^^xsd:string) AnnotationAssertion(rdfs:label "ribonuclease V activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.8"^^xsd:string) "Catalysis of the hydrolysis of poly(A), forming oligoribonucleotides and ultimately 3'-AMP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "rRNA endonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.10"^^xsd:string) "alpha-sarcin"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.10"^^xsd:string) "Catalysis of the hydrolysis of the phosphodiester linkage between guanosine and adenosine residues at one specific position in 28S rRNA from rat ribosomes."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.11"^^xsd:string) "DL 2"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.11"^^xsd:string) "endo-dextranase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.11"^^xsd:string) "dextranase DL 2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.11"^^xsd:string) "alpha-1,6-glucan-6-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.11"^^xsd:string) "1,6-alpha-D-glucan 6-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.11"^^xsd:string) "endodextranase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dextranase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.11"^^xsd:string) "dextran hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.11"^^xsd:string) "alpha-D-1,6-glucan-6-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.11"^^xsd:string) "Catalysis of the endohydrolysis of 1,6-alpha-D-glucosidic linkages in dextran."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.32"^^xsd:string) "Catalysis of the random hydrolysis of (1->3)-beta-D-glycosidic linkages in (1->3)-beta-D-xylans."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.32"^^xsd:string) "beta-1,3-xylanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.32"^^xsd:string) "xylanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.32"^^xsd:string) "endo-1,3-xylanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.32"^^xsd:string) "endo-1,3-beta-xylanase activity"^^xsd:string) AnnotationAssertion(rdfs:label "xylan endo-1,3-beta-xylosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.32"^^xsd:string) "endo-beta-1,3-xylanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.32"^^xsd:string) "1,3-beta-xylanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.32"^^xsd:string) "1,3-beta-D-xylan xylanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.32"^^xsd:string) "1,3-xylanase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.36"^^xsd:string) "hyaluronidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.36"^^xsd:string) "hyaluronate 3-glycanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.36"^^xsd:string) "Catalysis of the random hydrolysis of 1,3-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.36"^^xsd:string) "glucuronoglucosaminoglycan hyaluronate lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hyaluronoglucuronidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.36"^^xsd:string) "orgelase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-D-fucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.38"^^xsd:string) "beta-D-fucoside fucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.38"^^xsd:string) "beta-fucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.38"^^xsd:string) "Catalysis of the hydrolysis of terminal non-reducing beta-D-fucose residues in beta-D-fucosides."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-L-rhamnosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.43"^^xsd:string) "Catalysis of the hydrolysis of terminal, non-reducing beta-L-rhamnose residues in beta-L-rhamnosides."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.43"^^xsd:string) "beta-L-rhamnoside rhamnohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.44"^^xsd:string) "poly(1,2-alpha-L-fucoside-4-sulfate) glycanohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "fucoidanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.44"^^xsd:string) "Catalysis of the endohydrolysis of 1,2-alpha-L-fucoside linkages in fucoidan without release of sulfate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.60"^^xsd:string) "exo-maltotetraohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.60"^^xsd:string) "Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotetraose residues from the non-reducing chain ends."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.60"^^xsd:string) "maltotetraose-forming amylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.60"^^xsd:string) "glucan 1,4-alpha-maltotetrahydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.60"^^xsd:string) "1,4-alpha-D-glucan maltotetraohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucan 1,4-alpha-maltotetraohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.60"^^xsd:string) "G4-amylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.61"^^xsd:string) "1,3-1,4-alpha-D-glucan 4-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mycodextranase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.61"^^xsd:string) "Catalysis of the endohydrolysis of 1,4-alpha-D-glucosidic linkages in alpha-D-glucans containing both 1,3- and 1,4-bonds."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.64"^^xsd:string) "2,6-beta-D-fructan 6-beta-D-fructofuranosylfructohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.64"^^xsd:string) "2,6-beta-D-fructofuranan 6-(beta-D-fructosyl)-D-fructose-hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2,6-beta-fructan 6-levanbiohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.64"^^xsd:string) "2,6-beta-D-fructan 6-levanbiohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.64"^^xsd:string) "Catalysis of the hydrolysis of (2->6)-beta-D-fructofuranan, to remove successive disaccharide residues as levanbiose, i.e. 6-(beta-D-fructofuranosyl)-D-fructose, from the end of the chain."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.64"^^xsd:string) "levanbiose-producing levanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.64"^^xsd:string) "beta-2,6-fructan-6-levanbiohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucan endo-1,2-beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.71"^^xsd:string) "Catalysis of the random hydrolysis of (1->2)-glucosidic linkages in (1->2)-beta-D-glucans."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.71"^^xsd:string) "beta-D-1,2-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.71"^^xsd:string) "endo-(1->2)-beta-D-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.71"^^xsd:string) "endo-1,2-beta-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.71"^^xsd:string) "1,2-beta-D-glucan glucanohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.72"^^xsd:string) "1,3-beta-D-xylan xylohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "xylan 1,3-beta-xylosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.72"^^xsd:string) "Catalysis of the hydrolysis of successive xylose residues from the non-reducing termini of (1->3)-beta-D-xylans."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.72"^^xsd:string) "exo-beta-1,3'-xylanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.72"^^xsd:string) "1,3-beta-D-xylosidase, exo-1,3-beta-xylosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.72"^^xsd:string) "beta-1,3'-xylanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.72"^^xsd:string) "exo-1,3-beta-xylosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.77"^^xsd:string) "1,2-1,3-alpha-D-mannan mannohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.77"^^xsd:string) "exo-1,2-1,3-alpha-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.77"^^xsd:string) "Catalysis of the hydrolysis of (1->2) and (1->3) linkages in mannan, releasing mannose."^^xsd:string) AnnotationAssertion(rdfs:label "mannan 1,2-(1,3)-alpha-mannosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.81"^^xsd:string) "agarose 4-glycanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.81"^^xsd:string) "Catalysis of the hydrolysis of (1->4)-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.81"^^xsd:string) "agarose 3-glycanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.81"^^xsd:string) "AgaA"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.81"^^xsd:string) "agarase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.81"^^xsd:string) "AgaB"^^xsd:string) AnnotationAssertion(rdfs:label "beta-agarase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.82"^^xsd:string) "exopolygalacturonosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.82"^^xsd:string) "exopolygalacturanosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "exo-poly-alpha-galacturonosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.82"^^xsd:string) "Catalysis of the hydrolysis of pectic acid from the non-reducing end, releasing digalacturonate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.83"^^xsd:string) "Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose in kappa-carrageenans."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.83"^^xsd:string) "kappa-carrageenan 4-beta-D-glycanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.83"^^xsd:string) "kappa-carrageenan 4-beta-D-glycanohydrolase (configuration-retaining) activity"^^xsd:string) AnnotationAssertion(rdfs:label "kappa-carrageenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.84"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "glucosidase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.84"^^xsd:string) "Catalysis of the hydrolysis of terminal (1->3)-alpha-D-glucosidic links in 1,3-alpha-D-glucans."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.84"^^xsd:string) "1,3-alpha-D-glucan 3-glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.84"^^xsd:string) "exo-1,3-alpha-glucanase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucan 1,3-alpha-glucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.85"^^xsd:string) "phospho-beta-D-galactosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "6-phospho-beta-galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.85"^^xsd:string) "phospho-beta-galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.85"^^xsd:string) "beta-D-phosphogalactoside galactohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.85"^^xsd:string) "6-phospho-beta-D-galactoside 6-phosphogalactohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.85"^^xsd:string) "6-phospho-beta-D-galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.85"^^xsd:string) "Catalysis of the reaction: a 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.87"^^xsd:string) "Catalysis of the random hydrolysis of (1->3)-alpha-D-galactosidic linkages in Aerobacter aerogenes capsular polysaccharide."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.87"^^xsd:string) "polysaccharide depolymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.87"^^xsd:string) "aerobacter-capsular-polysaccharide galactohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.87"^^xsd:string) "capsular polysaccharide galactohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "capsular-polysaccharide endo-1,3-alpha-galactosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peptidoglycan beta-N-acetylmuramidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.92"^^xsd:string) "exo-beta-acetylmuramidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.92"^^xsd:string) "exo-beta-N-acetylmuramidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.92"^^xsd:string) "peptidoglycan beta-N-acetylmuramoylexohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.92"^^xsd:string) "Catalysis of the hydrolysis of terminal, non-reducing N-acetylmuramic residues."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.92"^^xsd:string) "beta-2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-D-glucoside acetamidodeoxyglucohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucan 1,6-alpha-isomaltosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.94"^^xsd:string) "Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in polysaccharides, to remove successive isomaltose units from the non-reducing ends of the chains."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.94"^^xsd:string) "isomaltodextranase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.94"^^xsd:string) "G2-dextranase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.94"^^xsd:string) "exo-isomaltohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.94"^^xsd:string) "isomalto-dextranase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.94"^^xsd:string) "1,6-alpha-D-glucan isomaltohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.95"^^xsd:string) "exo-isomaltotriohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.95"^^xsd:string) "1,6-alpha-D-glucan isomaltotriohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.95"^^xsd:string) "Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains."^^xsd:string) AnnotationAssertion(rdfs:label "dextran 1,6-alpha-isomaltotriosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.96"^^xsd:string) "glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.96"^^xsd:string) "Catalysis of the endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.96"^^xsd:string) "endo-beta-N-acetylglucosaminidase F activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.96"^^xsd:string) "endo-beta-acetylglucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.96"^^xsd:string) "endo-N-acetyl-beta-D-glucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.96"^^xsd:string) "mannosyl-glycoprotein endo-beta-N-acetylglucosamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.96"^^xsd:string) "endo-beta-N-acetylglucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.96"^^xsd:string) "endoglycosidase S activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.96"^^xsd:string) "endo-beta-N-acetylglucosaminidase D activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.96"^^xsd:string) "di-N-acetylchitobiosyl beta-N-acetylglucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.96"^^xsd:string) "glycopeptide-D-mannosyl-4-N-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.96"^^xsd:string) "endo-beta-N-acetylglucosaminidase L activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.96"^^xsd:string) "N,N'-diacetylchitobiosyl beta-N-acetylglucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.96"^^xsd:string) "endo-beta-(1->4)-N-acetylglucosaminidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.96"^^xsd:string) "endoglycosidase H activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.96"^^xsd:string) "mannosyl-glycoprotein 1,4-N-acetamidodeoxy-beta-D-glycohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.96"^^xsd:string) "endo-beta-N-acetylglucosaminidase H activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.96"^^xsd:string) "endo-N-acetyl-beta-glucosaminidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.97"^^xsd:string) "D-galactosyl-N-acetyl-alpha-D-galactosamine D-galactosyl-N-acetyl-galactosaminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.97"^^xsd:string) "endo-alpha-acetylgalactosaminidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycopeptide alpha-N-acetylgalactosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.97"^^xsd:string) Annotation( "MetaCyc:3.2.1.97-RXN"^^xsd:string) "Catalysis of the reaction: D-galactosyl-3-(N-acetyl-alpha-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-alpha-D-galactosamine + L-serine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.97"^^xsd:string) "endo-alpha-N-acetylgalactosaminidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.98"^^xsd:string) "exo-maltohexaohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.98"^^xsd:string) "Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltohexaose residues from the non-reducing chain ends."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.98"^^xsd:string) "G6-amylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.98"^^xsd:string) "maltohexaose-producing amylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucan 1,4-alpha-maltohexaosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.98"^^xsd:string) "1,4-alpha-D-glucan maltohexaohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.100"^^xsd:string) "exo-1,4-beta-mannobiohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.100"^^xsd:string) "1,4-beta-D-mannan mannobiohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.100"^^xsd:string) "exo-beta-mannanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.100"^^xsd:string) "mannan 1,4-beta-mannobiosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannan 1,4-mannobiosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.100"^^xsd:string) "Catalysis of the hydrolysis of (1->4)-beta-D-mannosidic linkages in (1->4)-beta-D-mannans, to remove successive mannobiose residues from the non-reducing chain ends."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "blood-group-substance endo-1,4-beta-galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.102"^^xsd:string) "Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A and B substances."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.102"^^xsd:string) "endo-beta-galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.102"^^xsd:string) "blood-group-substance 1,4-beta-D-galactanohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.103"^^xsd:string) "endo-beta-galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.103"^^xsd:string) "keratanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.103"^^xsd:string) "keratan sulfate endogalactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.103"^^xsd:string) "Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in keratan sulfate."^^xsd:string) AnnotationAssertion(rdfs:label "keratan-sulfate endo-1,4-beta-galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.103"^^xsd:string) "keratan-sulfate 1,4-beta-D-galactanohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.109"^^xsd:string) "galactosaminoglycan glycanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.109"^^xsd:string) "Catalysis of the endohydrolysis of (1->4)-alpha-D-galactosaminidic linkages in poly(D-galactosamine)."^^xsd:string) AnnotationAssertion(rdfs:label "endogalactosaminidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.111"^^xsd:string) "almond emulsin fucosidase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.111"^^xsd:string) "3-alpha-L-fucosyl-N-acetylglucosaminyl-glycoprotein fucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.111"^^xsd:string) "Catalysis of the hydrolysis of (1->3) linkages between alpha-L-fucose and N-acetylglucosamine residues in glycoproteins."^^xsd:string) AnnotationAssertion(rdfs:label "1,3-alpha-L-fucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.115"^^xsd:string) "Catalysis of the hydrolysis of (1->2)-alpha-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, producing free D-glucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.115"^^xsd:string) "dextran 1,2-alpha-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.115"^^xsd:string) "1,2-alpha-D-glucosyl-branched-dextran 2-glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.115"^^xsd:string) "dextran alpha-1,2 debranching enzyme"^^xsd:string) AnnotationAssertion(rdfs:label "branched-dextran exo-1,2-alpha-glucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucan 1,4-alpha-maltotriohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.116"^^xsd:string) "maltotriohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.116"^^xsd:string) "1,4-alpha-D-glucan maltotriohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.116"^^xsd:string) "exo-maltotriohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.116"^^xsd:string) "Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotriose residues from the non-reducing chain ends."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.120"^^xsd:string) "oligoxyloglucan xyloglucohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oligoxyloglucan beta-glycosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.120"^^xsd:string) "oligoxyloglucan hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.120"^^xsd:string) "Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic links in oligoxyloglucans so as to remove successive isoprimeverose (i.e. alpha-xylo-1,6-beta-D-glucosyl-) residues from the non-reducing chain ends."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.120"^^xsd:string) "isoprimeverose-producing oligoxyloglucan hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.121"^^xsd:string) "polymannuronic acid polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.121"^^xsd:string) "Catalysis of the endohydrolysis of the D-mannuronide linkages of polymannuronate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.121"^^xsd:string) "poly(mannuronide) mannuronohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "polymannuronate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.124"^^xsd:string) "capsular-polysaccharide 3-deoxy-D-manno-2-octulosonohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.124"^^xsd:string) "octulofuranosylono hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.124"^^xsd:string) "octulosylono hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.124"^^xsd:string) "octulopyranosylonohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-deoxy-2-octulosonidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.124"^^xsd:string) "Catalysis of the endohydrolysis of the beta-ketopyranosidic linkages of 3-deoxy-D-manno-2-octulosonate in capsular polysaccharides."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.124"^^xsd:string) "2-keto-3-deoxyoctonate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.127"^^xsd:string) "Catalysis of the hydrolysis of (1->6) linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin."^^xsd:string) AnnotationAssertion(rdfs:label "1,6-alpha-L-fucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.127"^^xsd:string) "1,6-L-fucosyl-N-acetyl-D-glucosaminylglycopeptide fucohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.131"^^xsd:string) "xylan alpha-D-1,2-(4-O-methyl)glucuronohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "xylan alpha-1,2-glucuronosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.131"^^xsd:string) "1,2-alpha-glucuronidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.131"^^xsd:string) "Catalysis of the hydrolysis of alpha-D-(1->2)-(4-O-methyl)glucuronosyl links in the main chain of hardwood xylans."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.131"^^xsd:string) "alpha-(1->2)-glucuronidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.136"^^xsd:string) "glucuronoxylanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.136"^^xsd:string) "Catalysis of the endohydrolysis of (1->4)-beta-D-xylosyl links in some glucuronoarabinoxylans."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.136"^^xsd:string) "feraxan endoxylanase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucuronoarabinoxylan endo-1,4-beta-xylanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.136"^^xsd:string) "feraxanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.136"^^xsd:string) "glucuronoarabinoxylan 1,4-beta-D-xylanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.136"^^xsd:string) "glucuronoxylan xylanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.136"^^xsd:string) "endoarabinoxylanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.136"^^xsd:string) "glucuronoxylan xylohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.137"^^xsd:string) "Catalysis of the hydrolysis of (1->2)-alpha-D- and (1->6)-alpha-D- linkages in mannan, releasing D-mannose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.137"^^xsd:string) "1,2-1,6-alpha-D-mannan D-mannohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.137"^^xsd:string) "exo-1,2-1,6-alpha-mannosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannan exo-1,2-1,6-alpha-mannosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.141"^^xsd:string) "maltooligosyl trehalose trehalohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.141"^^xsd:string) "malto-oligosyltrehalose trehalohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.141"^^xsd:string) "4-alpha-D-{(1,4)-alpha-D-glucano}trehalose glucanohydrolase (trehalose-producing) activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.141"^^xsd:string) "4-alpha-D-{(1->4)-alpha-D-glucano}trehalose glucanohydrolase (trehalose-producing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.141"^^xsd:string) "Catalysis of the hydrolysis of alpha-(1->4)-D-glucosidic linkage in 4-alpha-D-{(1->4)-alpha-D-glucanosyl}n trehalose to yield trehalose and alpha-(1->4)-D-glucan."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.145"^^xsd:string) "galactan (1->3)-beta-D-galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.145"^^xsd:string) "Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in (1->3)-beta-D-galactopyranans."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.145"^^xsd:string) "galactan (1,3)-beta-D-galactosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactan 1,3-beta-galactosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.146"^^xsd:string) "exo-beta-D-galactofuranosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.146"^^xsd:string) "exo-beta-galactofuranosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.146"^^xsd:string) "Catalysis of the hydrolysis of terminal non-reducing beta-D-galactofuranosides, releasing galactose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.146"^^xsd:string) "beta-D-galactofuranosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-galactofuranosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.146"^^xsd:string) "beta-D-galactofuranoside hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oligoxyloglucan reducing-end-specific cellobiohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.150"^^xsd:string) "Catalysis of the hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-(1->4) linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.150"^^xsd:string) "oligoxyloglucan reducing-end cellobiohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.150"^^xsd:string) "oligoxyloglucan reducing end-specific cellobiohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.151"^^xsd:string) "XH"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.151"^^xsd:string) "1,4-beta-D-glucan glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.151"^^xsd:string) "xyloglucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.151"^^xsd:string) "Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the endohydrolysis of (1->4)-beta-D-glucosidic linkages in xyloglucan."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.151"^^xsd:string) "xyloglucan endo-beta-1,4-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.151"^^xsd:string) "XEG"^^xsd:string) AnnotationAssertion(rdfs:label "xyloglucan-specific endo-beta-1,4-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.151"^^xsd:string) "xyloglucanendohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.151"^^xsd:string) "[(1->6)-beta-D-xylo]-(1->4)-beta-D-glucan glucanohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.152"^^xsd:string) "Catalysis of the hydrolysis of the alpha-D-mannosyl-(1->6)-beta-D-mannosyl-(1->4)-beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequence of glycoprotein to alpha-D-mannosyl-(1->6)-D-mannose and beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequences."^^xsd:string) AnnotationAssertion(rdfs:label "mannosylglycoprotein endo-beta-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.152"^^xsd:string) "endo-beta-mannosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.153"^^xsd:string) "beta-(2,1)-linkage-specific fructan-beta-fructosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.153"^^xsd:string) "1-fructan exohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.153"^^xsd:string) "1-FEH II"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.153"^^xsd:string) "beta-(2,1)-D-fructan fructohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.153"^^xsd:string) "1-FEH w1"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.153"^^xsd:string) "1-FEH w2"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.153"^^xsd:string) "beta-(2,1)-fructan exohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "fructan beta-(2,1)-fructosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.153"^^xsd:string) "Catalysis of the hydrolysis of terminal, non-reducing (2->1) linked beta-D-fructofuranose residues in fructans."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.154"^^xsd:string) "6-FEH"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.154"^^xsd:string) "beta-(2,6)-fructan exohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.154"^^xsd:string) "Catalysis of the hydrolysis of terminal, non-reducing (2->6) linked beta-D-fructofuranose residues in fructans."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.154"^^xsd:string) "beta-(2,6)-D-fructan fructohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "fructan beta-(2,6)-fructosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.155"^^xsd:string) "Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the exohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.155"^^xsd:string) "Cel74A"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.155"^^xsd:string) "[(1->6)-alpha-D-xylo]-(1->4)-beta-D-glucan exo-glucohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "xyloglucan-specific exo-beta-1,4-glucanase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oligosaccharide reducing-end xylanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.156"^^xsd:string) "Rex"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.156"^^xsd:string) "reducing end xylose-releasing exo-oligoxylanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.156"^^xsd:string) "Catalysis of the hydrolysis of 1,4-beta-D-xylose residues from the reducing end of oligosaccharides."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.156"^^xsd:string) "beta-D-xylopyranosyl-(1->4)-beta-D-xylopyranosyl-(1->4)-beta-D-xylopyranose reducing-end xylanase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.157"^^xsd:string) "iota-carrageenan 4-beta-D-glycanohydrolase (configuration-inverting) activity"^^xsd:string) AnnotationAssertion(rdfs:label "iota-carrageenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.157"^^xsd:string) "Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose-2-sulfate in iota-carrageenans."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.158"^^xsd:string) "agarose 3-glycanohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-agarase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.158"^^xsd:string) "Catalysis of the endohydrolysis of 1,3-alpha-L-galactosidic linkages in agarose, yielding agarotetraose as the major product."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.158"^^xsd:string) "agarase A33 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.158"^^xsd:string) "agarase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-neoagaro-oligosaccharide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.159"^^xsd:string) "alpha-neoagarooligosaccharide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.159"^^xsd:string) "alpha-neoagaro-oligosaccharide 3-glycohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.159"^^xsd:string) "Catalysis of the hydrolysis of the 1,3-alpha-L-galactosidic linkages of neoagaro-oligosaccharides that are smaller than a hexamer, yielding 3,6-anhydro-L-galactose and D-galactose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.159"^^xsd:string) "alpha-NAOS hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-apiosyl-beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.161"^^xsd:string) "Catalysis of the reaction: 7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid + H2O = a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.161"^^xsd:string) "isoflavonoid-7-O-beta[D-apiosyl-(1->6)-beta-D-glucoside] disaccharidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.161"^^xsd:string) "isoflavonoid 7-O-beta-apiosyl-glucoside beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.161"^^xsd:string) "furcatin hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.161"^^xsd:string) "7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid beta-D-apiofuranosyl-(1->6)-D-glucohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lambda-carrageenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.162"^^xsd:string) "Catalysis of the endohydrolysis of beta-1,4-linkages in the backbone of lambda-carrageenan, resulting in the tetrasaccharide alpha-D-Galp2,6S2-(1->3)-beta-D-Galp2S-(1->4)-alpha-D-Galp2,6S2-(1->3)-D-Galp2S."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.162"^^xsd:string) "endo-beta-1,4-carrageenose 2,6,2'-trisulfate-hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.15"^^xsd:string) "DNA(hypoxanthine) glycohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.15"^^xsd:string) "Catalysis of the hydrolysis of DNA and polynucleotides, releasing free hypoxanthine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.15"^^xsd:string) "DNA-deoxyinosine deoxyribohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.15"^^xsd:string) "deoxyribonucleic acid glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.15"^^xsd:string) "hypoxanthine-DNA glycosylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "DNA-deoxyinosine glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.15"^^xsd:string) "DNA-deoxyinosine glycosidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.17"^^xsd:string) "deoxy-D-ribocyclobutadipyrimidine polynucleotidodeoxyribohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "deoxyribodipyrimidine endonucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.17"^^xsd:string) "PD-DNA glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.17"^^xsd:string) "pyrimidine dimer DNA-glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.17"^^xsd:string) "T4-induced UV endonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.17"^^xsd:string) "deoxyribonucleate pyrimidine dimer glycosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.17"^^xsd:string) "pyrimidine dimer DNA glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.17"^^xsd:string) "endonuclease V activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.17"^^xsd:string) "Catalysis of the cleavage of the N-glycosidic bond between the 5'-pyrimidine residue in cyclobutadipyrimidine (in DNA) and the corresponding deoxy-D-ribose residue."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.25"^^xsd:string) "N-methyl nucleoside hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-methyl nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.25"^^xsd:string) "N-MeNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.25"^^xsd:string) Annotation( "RHEA:10883"^^xsd:string) "Catalysis of the reaction: 7-methylxanthosine + H(2)O = 7-methylxanthine + H(+) + ribofuranose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.25"^^xsd:string) "7-methylxanthosine nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.25"^^xsd:string) "7-methylxanthosine ribohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.25"^^xsd:string) "methylpurine nucleosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.3.2.9"^^xsd:string) "mEH"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.9"^^xsd:string) "microsomal epoxide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.9"^^xsd:string) "arene-oxide hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.9"^^xsd:string) "microsomal epoxide hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.9"^^xsd:string) "aryl epoxide hydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.9"^^xsd:string) "microsomal epoxide hydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.9"^^xsd:string) "epoxide hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.9"^^xsd:string) "cis-epoxide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.9"^^xsd:string) "benzo(a)pyrene-4,5-epoxide hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.9"^^xsd:string) "epoxide hydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.9"^^xsd:string) "Catalysis of the reaction: cis-stilbene oxide + H2O = (+)-(1R,2R)-1,2-diphenylethane-1,2-diol."^^xsd:string) AnnotationAssertion(rdfs:label "cis-stilbene-oxide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.9"^^xsd:string) "benzo[a]pyrene-4,5-oxide hydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.3.2.11"^^xsd:string) "ChEH"^^xsd:string) AnnotationAssertion(rdfs:label "cholesterol-5,6-oxide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.11"^^xsd:string) "5,6alpha-epoxy-5alpha-cholestan-3beta-ol hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.11"^^xsd:string) "Catalysis of the reactions: 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol, and 5,6beta-epoxy-5beta-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.11"^^xsd:string) "cholesterol-epoxide hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.69"^^xsd:string) "glycosphingolipid amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.69"^^xsd:string) "Catalysis of the hydrolysis of gangliosides and neutral glycosphingolipids, releasing fatty acids to form the lyso-derivatives."^^xsd:string) AnnotationAssertion(rdfs:label "glycosphingolipid deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.69"^^xsd:string) "glycosphingolipid ceramide deacylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.70"^^xsd:string) "Catalysis of the hydrolysis of the amide bond in aculeacin A and related neutral lipopeptide antibiotics, releasing the long-chain fatty acid side-chain."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.70"^^xsd:string) "aculeacin-A amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aculeacin-A deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.70"^^xsd:string) "aculeacin A acylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-substituted formamide deformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.91"^^xsd:string) "Catalysis of the reaction: N-benzylformamide + H2O = formate + benzylamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.91"^^xsd:string) "NfdA"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.91"^^xsd:string) "N-benzylformamide amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.93"^^xsd:string) "GA"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.93"^^xsd:string) "7beta-(4-carboxybutanamido)cephalosporanic acid acylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.93"^^xsd:string) "cephalosporin C acylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.93"^^xsd:string) "(7R)-7-(4-carboxybutanamido)cephalosporanate amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.93"^^xsd:string) "GCA"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.93"^^xsd:string) "glutaryl-7-ACA acylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutaryl-7-aminocephalosporanic-acid acylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.93"^^xsd:string) "CA"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.93"^^xsd:string) "Catalysis of the reaction: (7R)-7-(4-carboxybutanamido)cephalosporanate + H2O = (7R)-7-aminocephalosporanate + glutarate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.93"^^xsd:string) "GL-7-ACA acylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.93"^^xsd:string) "glutaryl-7-aminocephalosporanic acid acylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.93"^^xsd:string) "cephalosporin acylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "gamma-glutamyl-gamma-aminobutyrate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.94"^^xsd:string) "4-(glutamylamino)butanoate amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.94"^^xsd:string) "PuuD"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.94"^^xsd:string) "YcjL"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.94"^^xsd:string) "gamma-glutamyl-GABA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.94"^^xsd:string) Annotation( "RHEA:19740"^^xsd:string) "Catalysis of the reaction: 4-(L-gamma-glutamylamino)butanoate + H(2)O = 4-aminobutanoate + L-glutamate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.95"^^xsd:string) Annotation( "RHEA:17364"^^xsd:string) "Catalysis of the reaction: 3-oxo-3-ureidopropanoate + H(2)O = H(+) + malonate + urea."^^xsd:string) AnnotationAssertion(rdfs:label "N-malonylurea hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.95"^^xsd:string) "3-oxo-3-ureidopropanoate amidohydrolase (urea- and malonate-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.95"^^xsd:string) "ureidomalonase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroxyisourate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.17"^^xsd:string) "HIUHase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.17"^^xsd:string) "5-hydroxyisourate amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.17"^^xsd:string) "5-hydroxyisourate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.17"^^xsd:string) Annotation( "RHEA:23739"^^xsd:string) "Catalysis of the reaction: 5-hydroxyisourate + H(2)O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.22"^^xsd:string) "PAH"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.22"^^xsd:string) Annotation( "RHEA:17004"^^xsd:string) "Catalysis of the reaction: amidinoproclavaminate + H(2)O = proclavaminate + urea."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.22"^^xsd:string) "proclavaminate amidino hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "proclavaminate amidinohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.22"^^xsd:string) "proclavaminic acid amidino hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.30"^^xsd:string) Annotation( "RHEA:19208"^^xsd:string) "Catalysis of the reaction: dCTP + 2 H(2)O = diphosphate + dUMP + H(+) + NH(4)(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.30"^^xsd:string) "dCTP aminohydrolase (dUMP-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "dCTP deaminase (dUMP-forming) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nucleoside phosphoacylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.24"^^xsd:string) "Catalysis of the hydrolysis of mixed phospho-anhydride bonds."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.24"^^xsd:string) "nucleoside-5'-phosphoacylate acylhydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(R)-2-haloacid dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.9"^^xsd:string) "D-2-haloacid dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.9"^^xsd:string) "D-DEX"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.9"^^xsd:string) "2-haloalkanoid acid halidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.9"^^xsd:string) "(R)-2-haloacid halidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.9"^^xsd:string) "2-haloalkanoic acid dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.9"^^xsd:string) "Catalysis of the reaction: (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.8.1.10"^^xsd:string) "DL-2-haloacid dehalogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-haloacid dehalogenase (configuration-inverting) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.10"^^xsd:string) "Catalysis of the reactions: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.10"^^xsd:string) "2-haloalkanoid acid halidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.10"^^xsd:string) "DL-2-haloacid halidohydrolase (inversion of configuration) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.10"^^xsd:string) "2-haloalkanoic acid dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.10"^^xsd:string) "DL-DEXi"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.10"^^xsd:string) "DL-2-haloacid dehalogenase (inversion of configuration) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.8.1.11"^^xsd:string) "2-haloalkanoic acid dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.11"^^xsd:string) "Catalysis of the reactions: (S)-2-haloacid + H2O = (S)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (R)-2-hydroxyacid + halide."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.11"^^xsd:string) "2-haloalkanoid acid halidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.11"^^xsd:string) "DL-2-haloacid dehalogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-haloacid dehalogenase (configuration-retaining) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.11"^^xsd:string) "DL-DEXr"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.11.1.3"^^xsd:string) "PPH"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.11.1.3"^^xsd:string) Annotation( "RHEA:16676"^^xsd:string) "Catalysis of the reaction: 3-phosphonopyruvate + H(2)O = phosphate + pyruvate."^^xsd:string) AnnotationAssertion(rdfs:label "phosphonopyruvate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphonopyruvate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.82"^^xsd:string) Annotation( "RHEA:20771"^^xsd:string) "Catalysis of the reaction: 3-phosphonopyruvate + 2 H(+) = CO(2) + phosphonoacetaldehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.82"^^xsd:string) "3-phosphonopyruvate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.82"^^xsd:string) "3-phosphonopyruvate carboxy-lyase (2-phosphonoacetaldehyde-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.84"^^xsd:string) "D-dopachrome tautomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.84"^^xsd:string) Annotation( "RHEA:18444"^^xsd:string) "Catalysis of the reaction: D-dopachrome + H(+) = 5,6-dihydroxyindole + CO(2)."^^xsd:string) AnnotationAssertion(rdfs:label "D-dopachrome decarboxylase activity"^^xsd:string) AnnotationAssertion( "dopachrome decarboxylase activity"^^xsd:string) AnnotationAssertion( "dopachrome conversion activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.84"^^xsd:string) "phenylpyruvate tautomerase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.84"^^xsd:string) "D-tautomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.84"^^xsd:string) "D-dopachrome carboxy-lyase (5,6-dihydroxyindole-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.84"^^xsd:string) "D-dopachrome carboxy-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.85"^^xsd:string) "SgbH"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.85"^^xsd:string) "3-dehydro-L-gulonate-6-phosphate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.85"^^xsd:string) "KGPDC"^^xsd:string) AnnotationAssertion(rdfs:label "3-dehydro-L-gulonate-6-phosphate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.85"^^xsd:string) Annotation( "RHEA:14356"^^xsd:string) "Catalysis of the reaction: 3-dehydro-L-gulonate 6-phosphate + H(+) = L-xylulose 5-phosphate + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.85"^^xsd:string) "SgaH"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.85"^^xsd:string) "3-keto-L-gulonate 6-phosphate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.85"^^xsd:string) "UlaD"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.85"^^xsd:string) "3-dehydro-L-gulonate-6-phosphate carboxy-lyase (L-xylulose-5-phosphate-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.86"^^xsd:string) "L-2,4-diaminobutanoate carboxy-lyase (propane-1,3-diamine-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.86"^^xsd:string) "L-2,4-diaminobutanoate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.86"^^xsd:string) "L-2,4-diaminobutyrate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.86"^^xsd:string) Annotation( "RHEA:15692"^^xsd:string) "Catalysis of the reaction: L-2,4-diaminobutyrate + H(+) = 1,3-diaminopropane + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.86"^^xsd:string) "DABA DC"^^xsd:string) AnnotationAssertion(rdfs:label "diaminobutyrate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.8"^^xsd:string) "tryptophan synthase alpha subunit activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.8"^^xsd:string) "IGL"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.8"^^xsd:string) "indole-3-glycerol phosphate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.8"^^xsd:string) "BX1"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.8"^^xsd:string) "TSA"^^xsd:string) AnnotationAssertion(rdfs:label "indole-3-glycerol-phosphate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.8"^^xsd:string) "(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase (indole-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.8"^^xsd:string) "Catalysis of the reaction: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde 3-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.8"^^xsd:string) "indole-3-glycerolphosphate D-glyceraldehyde-3-phosphate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.8"^^xsd:string) "indoleglycerolphosphate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.8"^^xsd:string) "tryptophan synthase alpha activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.8"^^xsd:string) "(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.8"^^xsd:string) "indole glycerol phosphate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.8"^^xsd:string) "indole synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxyisoflavanone dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.105"^^xsd:string) "Catalysis of the reaction: 2,7,4'-trihydroxyisoflavanone = daidzein + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.105"^^xsd:string) "2,7,4'-trihydroxyisoflavanone hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.105"^^xsd:string) "2,7,4'-trihydroxyisoflavanone hydro-lyase (daidzein-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bile-acid 7alpha-dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.106"^^xsd:string) Annotation( "RHEA:10439"^^xsd:string) "Catalysis of the reaction: 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oate = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.106"^^xsd:string) "7alpha,12alpha-dihydroxy-3-oxochol-4-enoate hydro-lyase (12alpha-hydroxy-3-oxochola-4,6-dienoate-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.106"^^xsd:string) "7alpha,12alpha-dihydroxy-3-oxochol-4-enoate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.106"^^xsd:string) "BA7 alpha dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.107"^^xsd:string) "D-3-hydroxyacyl-CoA dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.107"^^xsd:string) "(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.107"^^xsd:string) "(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase [(24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA-forming] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.107"^^xsd:string) "46 kDa hydratase 2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.107"^^xsd:string) "Catalysis of the reaction: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.108"^^xsd:string) "N4-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.108"^^xsd:string) "N-acetyldiaminobutyrate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.108"^^xsd:string) "EctC"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.108"^^xsd:string) Annotation( "RHEA:17284"^^xsd:string) "Catalysis of the reaction: N(4)-acetyl-L-2,4-diaminobutyrate = ectoine + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.108"^^xsd:string) "N-acetyldiaminobutanoate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.108"^^xsd:string) "L-ectoine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.108"^^xsd:string) "4-N-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "ectoine synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aldos-2-ulose dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.110"^^xsd:string) "Catalysis of the reactions: 1,5-anhydro-D-fructose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H2O; (1a) 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O and (1b) 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.110"^^xsd:string) "pyranosone dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.110"^^xsd:string) "AUDH"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.110"^^xsd:string) "1,5-anhydro-D-fructose dehydratase (microthecin-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.110"^^xsd:string) "1,5-anhydro-D-fructose hydro-lyase (microthecin-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.111"^^xsd:string) "1,5-anhydro-D-fructose hydro-lyase (ascopyrone-M-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.111"^^xsd:string) "AF dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.111"^^xsd:string) "1,5-anhydro-D-fructose hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.111"^^xsd:string) "1,5-anhydro-D-arabino-hex-2-ulose dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.111"^^xsd:string) "1,5-anhydro-D-fructose 4-dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.111"^^xsd:string) "AFDH"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.111"^^xsd:string) "Catalysis of the reaction: 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.111"^^xsd:string) "1,5-anhydro-D-fructose hydrolyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1,5-anhydro-D-fructose dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.2.14"^^xsd:string) "Catalysis of the reaction: (1->4)-beta-D-glucuronan = an oligosaccharide with 4-deoxy-beta-D-gluc-4-enuronosyl end + (1->4)-beta-D-glucuronan. This reaction is the eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides."^^xsd:string) AnnotationAssertion(rdfs:label "glucuronan lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.14"^^xsd:string) "(1,4)-beta-D-glucuronan lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.2.15"^^xsd:string) "sialglycoconjugate N-acylneuraminylhydrolase (2,7-cyclizing) activity"^^xsd:string) AnnotationAssertion(rdfs:label "anhydrosialidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.15"^^xsd:string) "anhydroneuraminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.15"^^xsd:string) "Catalysis of the reaction: an N-acetylneuraminate glycoside = 2,7-anhydro-alpha-N-acetylneuraminate + an alpha-sialyl group. This reaction is the elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.15"^^xsd:string) "sialidase L activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.15"^^xsd:string) "glycoconjugate sialyl-lyase (2,7-cyclizing) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.2.16"^^xsd:string) "Catalysis of the reaction: beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)]n-D-fructofuranoside = beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)](n-1)-D-fructofuranoside + di-beta-D-fructofuranose 2,6':2',6-dianhydride. This reaction is the production of di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by successively eliminating the diminishing (2->6)-beta-D-fructan (levan) chain from the terminal D-fructosyl-D-fructosyl disaccharide."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.16"^^xsd:string) "2,6-beta-D-fructan D-fructosyl-D-fructosyltransferase (forming di-beta-D-fructofuranose 2,6':2',6-dianhydride) activity"^^xsd:string) AnnotationAssertion(rdfs:label "levan fructotransferase (DFA-IV-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.16"^^xsd:string) "levan fructotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.16"^^xsd:string) "2,6-beta-D-fructan lyase (di-beta-D-fructofuranose-2,6':2',6-dianhydride-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.2.17"^^xsd:string) "Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose-beta-D-fructofuranose 1,2':1,2'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,1'-dianhydride (DFA I) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.17"^^xsd:string) "inulin D-fructosyl-D-fructosyltransferase (forming alpha-D-fructofuranose beta-D-fructofuranose 1,2':1',2-dianhydride) activity"^^xsd:string) AnnotationAssertion(rdfs:label "inulin fructotransferase (DFA-I-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.17"^^xsd:string) "inulin fructotransferase (depolymerizing, difructofuranose-1,2':2',1-dianhydride-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.17"^^xsd:string) "inulin fructotransferase (DFA-I-producing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.17"^^xsd:string) "inulin D-fructosyl-D-fructosyltransferase (1,2':1',2-dianhydride-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.17"^^xsd:string) "2,1-beta-D-fructan lyase (alpha-D-fructofuranose-beta-D-fructofuranose-1,2':2,1'-dianhydride-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.2.18"^^xsd:string) "inulinase II activity"^^xsd:string) AnnotationAssertion(rdfs:label "inulin fructotransferase (DFA-III-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.18"^^xsd:string) "inulin D-fructosyl-D-fructosyltransferase (forming alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.18"^^xsd:string) "inulase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.18"^^xsd:string) "2,1-beta-D-fructan lyase (alpha-D-fructofuranose-beta-D-fructofuranose-1,2':2,3'-dianhydride-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.18"^^xsd:string) "inulin fructotransferase (depolymerizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.18"^^xsd:string) "Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.18"^^xsd:string) "inulin D-fructosyl-D-fructosyltransferase (1,2':2,3'-dianhydride-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.18"^^xsd:string) "inulin fructotransferase (DFA-III-producing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.18"^^xsd:string) "inulin fructotransferase (depolymerizing, difructofuranose-1,2':2,3'-dianhydride-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.2.19"^^xsd:string) "ChnB"^^xsd:string) AnnotationAssertion(rdfs:label "chondroitin B lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.19"^^xsd:string) "chonB"^^xsd:string) AnnotationAssertion( "dermatan sulfate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.19"^^xsd:string) "chondroitinase B activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.19"^^xsd:string) "Catalysis of the reaction: dermatan sulfate = n 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate. This reaction is the eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S). Chondroitin sulfate B is also known as dermatan sulfate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.2.20"^^xsd:string) "Catalysis of the endolytic cleavage of beta-1,4-galactosaminic bonds between N-acetylgalactosamine and either D-glucuronic acid or L-iduronic acid to produce a mixture of Delta4-unsaturated oligosaccharides of different sizes that are ultimately degraded to Delta4-unsaturated tetra- and disaccharides."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.20"^^xsd:string) "chondroitin ABC eliminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.20"^^xsd:string) "ChS ABC lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.20"^^xsd:string) "ChS ABC lyase I activity"^^xsd:string) AnnotationAssertion(rdfs:label "chondroitin-sulfate-ABC endolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.20"^^xsd:string) "chondroitinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.20"^^xsd:string) "chondroitinase ABC activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.20"^^xsd:string) "chondroitin sulfate ABC endolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.20"^^xsd:string) "chondroitin sulfate ABC lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.20"^^xsd:string) "chondroitin sulfate ABC endoeliminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.2.21"^^xsd:string) "ChS ABC lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.21"^^xsd:string) "chondroitinase ABC activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.21"^^xsd:string) "chondroitin sulfate ABC exoeliminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.21"^^xsd:string) "chondroitin ABC eliminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.21"^^xsd:string) "chondroitinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "chondroitin-sulfate-ABC exolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.21"^^xsd:string) "chondroitin sulfate ABC lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.21"^^xsd:string) "ChS ABC lyase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.21"^^xsd:string) "chondroitin sulfate ABC exolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.21"^^xsd:string) "Catalysis of the exolytic cleavage of disaccharide residues from the non-reducing ends of both polymeric chondroitin sulfates and their oligosaccharide fragments."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.20"^^xsd:string) Annotation( "RHEA:10943"^^xsd:string) "Catalysis of the reaction: geranyl diphosphate = (4R)-limonene + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.20"^^xsd:string) "(+)-limonene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.20"^^xsd:string) "geranyldiphosphate diphosphate lyase [(+)-(R)-limonene-forming] activity"^^xsd:string) AnnotationAssertion(rdfs:label "(R)-limonene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.20"^^xsd:string) "geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-(4R)-limonene-forming] activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.21"^^xsd:string) "HVS"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.21"^^xsd:string) "pemnaspirodiene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.21"^^xsd:string) Annotation( "RHEA:10343"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + vetispiradiene."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.21"^^xsd:string) "vetispiradiene cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.21"^^xsd:string) "vetispiradiene-forming farnesyl pyrophosphate cyclase activity"^^xsd:string) AnnotationAssertion(rdfs:label "vetispiradiene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.21"^^xsd:string) "trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, vetispiradiene-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "germacradienol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.22"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.22"^^xsd:string) "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol-forming] activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.23"^^xsd:string) "(+)-germacrene A synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.23"^^xsd:string) Annotation( "RHEA:12519"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.23"^^xsd:string) "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (germacrene-A-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "germacrene-A synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.23"^^xsd:string) "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(+)-germacrene-A-forming] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.23"^^xsd:string) "(+)-(10R)-germacrene A synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.23"^^xsd:string) "GAS"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.23"^^xsd:string) "germacrene A synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.24"^^xsd:string) "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (amorpha-4,11-diene-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.24"^^xsd:string) Annotation( "RHEA:18328"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = amorpha-4,11-diene + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.24"^^xsd:string) "amorphadiene synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "amorpha-4,11-diene synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.25"^^xsd:string) "3S-linalool synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.25"^^xsd:string) "LIS"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.25"^^xsd:string) "geranyl-diphosphate diphosphate-lyase [(3S)-linalool-forming] activity"^^xsd:string) AnnotationAssertion(rdfs:label "S-linalool synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.25"^^xsd:string) Annotation( "RHEA:24119"^^xsd:string) "Catalysis of the reaction: geranyl diphosphate + H(2)O = (S)-linalool + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.26"^^xsd:string) "(-)-3R-linalool synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.26"^^xsd:string) Annotation( "RHEA:15812"^^xsd:string) "Catalysis of the reaction: geranyl diphosphate + H(2)O = (R)-linalool + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "R-linalool synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.26"^^xsd:string) "(3R)-linalool synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.26"^^xsd:string) "geranyl-diphosphate diphosphate-lyase [(3R)-linalool-forming] activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.27"^^xsd:string) "ISPS"^^xsd:string) AnnotationAssertion(rdfs:label "isoprene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.27"^^xsd:string) "dimethylallyl-diphosphate diphosphate-lyase (isoprene-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.27"^^xsd:string) Annotation( "RHEA:13372"^^xsd:string) "Catalysis of the reaction: dimethylallyl diphosphate = diphosphate + isoprene."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.27"^^xsd:string) "ISPC"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.24"^^xsd:string) "SuyAB"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.24"^^xsd:string) Annotation( "RHEA:21431"^^xsd:string) "Catalysis of the reaction: 3-sulfolactate = pyruvate + sulfite."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.24"^^xsd:string) "Suy"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.24"^^xsd:string) "3-sulfolactate bisulfite-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.24"^^xsd:string) "3-sulfolactate bisulfite-lyase (pyruvate-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfolactate sulfo-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.25"^^xsd:string) "L-cysteate sulfo-lyase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.25"^^xsd:string) "L-cysteate bisulfite-lyase (deaminating; pyruvate-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.25"^^xsd:string) "CuyA"^^xsd:string) AnnotationAssertion(rdfs:label "L-cysteate sulfo-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.25"^^xsd:string) Annotation( "RHEA:13444"^^xsd:string) "Catalysis of the reaction: L-cysteate + H(2)O = NH(4)(+) + pyruvate + sulfite."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "FAD-AMP lyase (cyclizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.15"^^xsd:string) "FMN cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.15"^^xsd:string) "FAD AMP-lyase (riboflavin-cyclic-4',5'-phosphate-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.15"^^xsd:string) "Catalysis of the reaction: FAD = AMP + riboflavin cyclic-4',5'-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.15"^^xsd:string) "FAD AMP-lyase (cyclic-FMN-forming) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.99.1.5"^^xsd:string) "OxdA"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.5"^^xsd:string) "Catalysis of the reaction: an aliphatic aldoxime = an aliphatic nitrile + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.5"^^xsd:string) "aliphatic aldoxime hydro-lyase (aliphatic-nitrile-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "aliphatic aldoxime dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.5"^^xsd:string) "aliphatic aldoxime hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.22"^^xsd:string) "SgaU"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.22"^^xsd:string) "L-xylulose 5-phosphate 3-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.22"^^xsd:string) "UlaE"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.22"^^xsd:string) "Catalysis of the reaction: L-ribulose 5-phosphate = L-xylulose 5-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "L-ribulose-5-phosphate 3-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.3.13"^^xsd:string) "eicosapentaenoate cis-delta5,8,11,14,17-eicosapentaenoate cis-delta5-trans-delta7,9-cis-delta14,17 isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "polyenoic fatty acid isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.13"^^xsd:string) "(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate delta8,11-delta7,8-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.13"^^xsd:string) "(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate delta8,11-delta7,9-isomerase (trans-double-bond-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.13"^^xsd:string) Annotation( "RHEA:14892"^^xsd:string) "Catalysis of the reaction: all-cis-icosa-5,8,11,14,17-pentaenoate = (5Z,7E,9E,14Z,17Z)-icosapentaenoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.13"^^xsd:string) "(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate delta8,11-delta7,9-isomerase (trans-double-bond-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.13"^^xsd:string) "PFI"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "trans-2-decenoyl-acyl-carrier-protein isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.14"^^xsd:string) "trans-2-decenoyl-ACP isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.14"^^xsd:string) "trans-2,cis-3-decenoyl-ACP isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.14"^^xsd:string) Annotation( "IMG:02508"^^xsd:string) "Catalysis of the reaction: trans-dec-2-enoyl-[acyl-carrier protein] = cis-dec-3-enoyl-[acyl-carrier protein]."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.14"^^xsd:string) "trans-2-cis-3-decenoyl-ACP isomerase activity"^^xsd:string) AnnotationAssertion( "trans-2, cis-3 decenoyl-[acyl-carrier-protein] isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.14"^^xsd:string) "FabM"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.14"^^xsd:string) "beta-hydroxydecanoyl thioester dehydrase activity"^^xsd:string) AnnotationAssertion( "trans-2, cis-3 decenoyl-ACP isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.14"^^xsd:string) "decenoyl-acyl-carrier-protein delta2-trans-delta3-cis-isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.3.15"^^xsd:string) "1,5-anhydro-D-glycero-hex-3-en-2-ulose tautomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.15"^^xsd:string) "APTM"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.15"^^xsd:string) "ascopyrone isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ascopyrone tautomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.15"^^xsd:string) "ascopyrone intramolecular oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.15"^^xsd:string) "1,5-anhydro-D-glycero-hex-3-en-2-ulose delta3-delta1-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.15"^^xsd:string) "ascopyrone P tautomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.15"^^xsd:string) "Catalysis of the reaction: 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.15"^^xsd:string) "APM tautomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.99.9"^^xsd:string) "NSY"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.9"^^xsd:string) Annotation( "RHEA:10131"^^xsd:string) "Catalysis of the reaction: all-trans-violaxanthin = all-trans-neoxanthin."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.9"^^xsd:string) "violaxanthin-neoxanthin isomerase (epoxide-opening) activity"^^xsd:string) AnnotationAssertion(rdfs:label "neoxanthin synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.4.3"^^xsd:string) "3HAP mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.4.3"^^xsd:string) "3-(hydroxyamino)phenol hydroxymutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.4.3"^^xsd:string) "3-hydroxylaminophenol mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.4.3"^^xsd:string) Annotation( "RHEA:20580"^^xsd:string) "Catalysis of the reaction: 3-hydroxyaminophenol = aminohydroquinone."^^xsd:string) AnnotationAssertion(rdfs:label "3-(hydroxyamino)phenol mutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.99.18"^^xsd:string) "Catalysis of the reaction: 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.18"^^xsd:string) "N5-CAIR mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.18"^^xsd:string) "N5-carboxyaminoimidazole ribonucleotide mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.18"^^xsd:string) "PurE"^^xsd:string) AnnotationAssertion(rdfs:label "5-(carboxyamino)imidazole ribonucleotide mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.18"^^xsd:string) "class I PurE"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.18"^^xsd:string) "5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole carboxymutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.1.11"^^xsd:string) "YcjK"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.11"^^xsd:string) "L-glutamate:putrescine ligase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.11"^^xsd:string) Annotation( "RHEA:13636"^^xsd:string) "Catalysis of the reaction: L-glutamate + ATP + putrescine = gamma-L-glutamylputrescine + ADP + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.11"^^xsd:string) "gamma-glutamylputrescine synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamate-putrescine ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.1.12"^^xsd:string) "UDP-MurNAc-pentapeptide:D-aspartate ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.12"^^xsd:string) "Catalysis of the reaction: ATP + D-aspartate + [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n = [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + ADP + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.12"^^xsd:string) "aslfm"^^xsd:string) AnnotationAssertion(rdfs:label "D-aspartate ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.12"^^xsd:string) "D-aspartate:[beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n ligase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.12"^^xsd:string) "D-aspartic acid-activating enzyme"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.28"^^xsd:string) "bacilysin synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.28"^^xsd:string) "YwfE"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.28"^^xsd:string) "L-amino acid ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.28"^^xsd:string) "L-amino acid alpha-ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-amino-acid alpha-ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.28"^^xsd:string) "Catalysis of the reaction: ATP + an L-amino acid + an L-amino acid = ADP + phosphate + L-aminoacyl-L-amino acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(carboxyethyl)arginine beta-lactam-synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.4"^^xsd:string) Annotation( "RHEA:23623"^^xsd:string) "Catalysis of the reaction: N(2)-(2-carboxyethyl)-L-arginine + ATP = AMP + deoxyamidinoproclavaminate + diphosphate + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.4"^^xsd:string) "L-N2-(2-carboxyethyl)arginine cyclo-ligase (AMP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.4"^^xsd:string) "beta-lactam synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.3.4"^^xsd:string) "L-2-N-(2-carboxyethyl)arginine cyclo-ligase (AMP-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5-(carboxyamino)imidazole ribonucleotide synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.18"^^xsd:string) "5-amino-1-(5-phospho-D-ribosyl)imidazole:carbon-dioxide ligase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.18"^^xsd:string) "PurK"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.18"^^xsd:string) Annotation( "RHEA:19320"^^xsd:string) "Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + bicarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 3 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.18"^^xsd:string) "N5-CAIR synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.18"^^xsd:string) "N5-carboxyaminoimidazole ribonucleotide synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.4.1.7"^^xsd:string) "OGC"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.7"^^xsd:string) "carboxylating factor for ICDH"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.7"^^xsd:string) "oxalosuccinate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.7"^^xsd:string) Annotation( "RHEA:20428"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + ATP + bicarbonate = ADP + 2 H(+) + oxalosuccinate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.7"^^xsd:string) "CFI"^^xsd:string) AnnotationAssertion(rdfs:label "2-oxoglutarate carboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.46"^^xsd:string) "spermidine:eIF5A-lysine 4-aminobutyltransferase (propane-1,3-diamine-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.46"^^xsd:string) Annotation( "GOC:pde"^^xsd:string) Annotation( "MetaCyc:2.5.1.46-RXN"^^xsd:string) "Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. Four sub-reactions have been identified,in which the intermediates remain tightly associated with the enzyme: spermidine + NAD+ = dehydrospermidine + NADH; dehydrospermidine + [enzyme]-lysine = N-(4-aminobutylidene)-[enzyme]-lysine + propane-1,3-diamine; N-(4-aminobutylidene)-[enzyme]-lysine + [eIF5A-precursor]-lysine = N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + [enzyme]-lysine; N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ = [eIF5A-precursor]-deoxyhypusine + NAD+."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.46"^^xsd:string) "eIF5A-precursor-lysine:spermidine 4-aminobutyltransferase (propane-1,3-diamine-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.46"^^xsd:string) "eIF-5A-deoxyhypusine synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "deoxyhypusine synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:17641464"^^xsd:string) "Catalysis of the removal of 8-oxo-7,8-dihydroguanine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar."^^xsd:string) AnnotationAssertion(rdfs:label "8-oxo-7,8-dihydroguanine DNA N-glycosylase activity"^^xsd:string) AnnotationAssertion( "8-oxoG DNA N-glycosylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipid(in) = ADP + phosphate + lipid(out)."^^xsd:string) AnnotationAssertion(rdfs:label "lipid-transporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sterol(in) = ADP + phosphate + sterol(out)."^^xsd:string) AnnotationAssertion(rdfs:label "sterol-transporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5-formyluracil DNA N-glycosylase activity"^^xsd:string) AnnotationAssertion( "5-foU DNA N-glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:17641464"^^xsd:string) "Catalysis of the removal of 5-formyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:17641464"^^xsd:string) "Catalysis of the removal of 5-hydroxymethyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar."^^xsd:string) AnnotationAssertion(rdfs:label "5-hydroxymethyluracil DNA N-glycosylase activity"^^xsd:string) AnnotationAssertion( "5-hmU DNA N-glycosylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "poly(rG) binding"^^xsd:string) AnnotationAssertion( "poly(G) binding, within an RNA molecule"^^xsd:string) AnnotationAssertion(rdfs:label "poly(G) binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a sequence of guanine residues in an RNA molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "estrogen response element binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) Annotation( "PMID:15036253"^^xsd:string) Annotation( "PMID:17975005"^^xsd:string) "Interacting selectively and non-covalently with the estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen."^^xsd:string) AnnotationAssertion( "ERE binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA strand-exchange activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mcc"^^xsd:string) Annotation( "PMID:9769100"^^xsd:string) "Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "deoxyribonucleic acid polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and primer."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "deoxyribonucleic polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "DNA nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "deoxyribonucleate nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.7"^^xsd:string) "deoxynucleate polymerase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "ribonucleic polymerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "ribonucleate polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "ribonucleate nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "ribonucleic acid polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "ribonucleic transcriptase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "C ribonucleic acid formation factors"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "transcriptase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "ribonucleic acid nucleotidyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "ribonucleic acid transcriptase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "RNA transcriptase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "RNA nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.6"^^xsd:string) "C RNA formation factors"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) "Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + nucleotidylaminoglycoside."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.47"^^xsd:string) "streptomycin-spectinomycin adenylyltransferase activity"^^xsd:string) AnnotationAssertion( "aminoglycoside adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.47"^^xsd:string) "streptomycin adenylate synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aminoglycoside nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.47"^^xsd:string) "streptomycin adenylylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.47"^^xsd:string) "streptomycin adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.47"^^xsd:string) "streptomycin adenyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "kanamycin acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + N-acetylaminoglycoside."^^xsd:string) AnnotationAssertion(rdfs:label "aminoglycoside N-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 1-N-acetylaminoglycoside. This is acetylation of the 1-amino group of the central deoxystreptamine ring."^^xsd:string) AnnotationAssertion(rdfs:label "aminoglycoside 1-N-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: ATP + aminoglycoside = ADP + phosphoaminoglycoside."^^xsd:string) AnnotationAssertion(rdfs:label "aminoglycoside phosphotransferase activity"^^xsd:string) AnnotationAssertion( "aminoglycoside kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "squalene cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) Annotation( "PMID:18033581"^^xsd:string) "Catalysis of the reaction: squalene = triterpene."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tetrahymanol cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:9493"^^xsd:string) Annotation( "GOC:cb"^^xsd:string) Annotation( "PMID:18033581"^^xsd:string) "Catalysis of the reaction: squalene = tetrahymanol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "marneral synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) Annotation( "PMID:16425307"^^xsd:string) Annotation( "PMID:18033581"^^xsd:string) Annotation( "http://www.wiley-vch.de/contents/jc_2002/2006/z503420_s.pdf"^^xsd:string) "Catalysis of the reaction: oxidosqualene = marneral."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) Annotation( "PMID:16774269"^^xsd:string) Annotation( "PMID:17474751"^^xsd:string) "Catalysis of the reaction: oxidosqualene + H2O = arabidiol ((13R,14R,17E)-malabarica-17,21-diene-3beta,14-diol)."^^xsd:string) AnnotationAssertion(rdfs:label "arabidiol synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) Annotation( "PMID:18033581"^^xsd:string) "Catalysis of the reaction: oxidosqualene = cucurbitadienol."^^xsd:string) AnnotationAssertion(rdfs:label "cucurbitadienol synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sterol deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rb"^^xsd:string) Annotation( "PMID:18034159"^^xsd:string) "Catalysis of the hydrolysis of an acetyl group or groups from an acetylated sterol."^^xsd:string) AnnotationAssertion(rdfs:label "steryl deacetylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Interacting selectively and non-covalently with an apolipoprotein, the protein component of a lipoprotein complex."^^xsd:string) AnnotationAssertion(rdfs:label "apolipoprotein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "apolipoprotein A-I binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Interacting selectively and non-covalently with apolipoprotein A-I."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "apolipoprotein A-I receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:16443932"^^xsd:string) "Combining with apolipoprotein A-I and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a very-low-density lipoprotein particle, a triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm."^^xsd:string) AnnotationAssertion(rdfs:label "very-low-density lipoprotein particle binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) "very-low-density lipoprotein binding"^^xsd:string) AnnotationAssertion( "VLDL binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "apolipoprotein receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Interacting selectively and non-covalently with an apolipoprotein receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "apolipoprotein A-I receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Interacting selectively and non-covalently with an apolipoprotein A-I receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN0-4361"^^xsd:string) Annotation( "PMID:11279237"^^xsd:string) "Catalysis of the reaction: D-beta-D-heptose 1,7-bisphosphate + H2O = D-beta-D-heptose 1-phosphate + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "D,D-heptose 1,7-bisphosphate phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "PMID:11807558"^^xsd:string) "Catalysis of the movement of glycolipids from one membrane face to the other (glycolipid 'flippase' activity)."^^xsd:string) AnnotationAssertion( "flippase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycolipid-translocating activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GTP-dependent protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) Annotation( "PMID:17200152"^^xsd:string) "Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of GTP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-acetylpeptide."^^xsd:string) AnnotationAssertion(rdfs:label "peptide N-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "thiamine:proton symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "thiamine:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "thiamin:proton symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "thiamin:hydrogen symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "high-affinity thiamine:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "high-affinity thiamin:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "high-affinity thiamin:proton symporter activity"^^xsd:string) AnnotationAssertion( "high-affinity thiamine:proton symporter activity"^^xsd:string) AnnotationAssertion( "high affinity thiamin:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in). In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ethanolamine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "monoethanolamine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rn"^^xsd:string) Annotation( "PMID:3514579"^^xsd:string) "Catalysis of the transfer of ethanolamine from one side of the membrane to the other. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine."^^xsd:string) AnnotationAssertion( "2-aminoethanol transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "ethanolamine permease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with any glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes."^^xsd:string) AnnotationAssertion(rdfs:label "GPI anchor binding"^^xsd:string) AnnotationAssertion( "glycosylphosphatidylinositol binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein kinase A catalytic subunit binding"^^xsd:string) AnnotationAssertion( "PKA catalytic subunit binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with one or both of the catalytic subunits of protein kinase A."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "PKA regulatory subunit binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with one or both of the regulatory subunits of protein kinase A."^^xsd:string) AnnotationAssertion( "protein kinase A anchoring activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein kinase A regulatory subunit binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "mitochondrial polymerase transcription factor activity"^^xsd:string) AnnotationAssertion( "mitochondrial transcription factor activity"^^xsd:string) AnnotationAssertion( "mitochondrial transcription initiation factor activity"^^xsd:string) AnnotationAssertion(rdfs:label "mitochondrial RNA polymerase binding promoter specificity activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a mitochondrial RNA polymerase to form a holoenzyme complex and also, while present in the holoenzyme, interacting with promoter sequences in order to confer sequence specific recognition of mitochondrial promoter DNA sequence motifs."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "chlorophyll(ide) b reductase activity"^^xsd:string) AnnotationAssertion( "chlorophyll b reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.294"^^xsd:string) Annotation( "MetaCyc:RXN-7678"^^xsd:string) "Catalysis of the reaction: 71-hydroxychlorophyll(ide) a + NAD(P)+ = chlorophyll(ide) b + NAD(P)H + H+."^^xsd:string) AnnotationAssertion( "Chl b reductase activity"^^xsd:string) AnnotationAssertion( "chlorophyllide b reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:se"^^xsd:string) "Catalysis of the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "nicotinamide riboside transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.28"^^xsd:string) Annotation( "KEGG:R09119"^^xsd:string) Annotation( ) "ent-copalyl-diphosphate diphosphate-lyase (ent-cassa-12,15-diene-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "ent-cassa-12,15-diene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.28"^^xsd:string) Annotation( "RHEA:25535"^^xsd:string) "Catalysis of the reaction: ent-copalyl diphosphate = ent-cassa-12,15-diene + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "stemar-13-ene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R09115"^^xsd:string) Annotation( ) "9alpha-copalyl-diphosphate diphosphate-lyase (stemar-13-ene-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-4882"^^xsd:string) Annotation( "RHEA:25555"^^xsd:string) "Catalysis of the reaction: 9-alpha-copalyl diphosphate = stemar-13-ene + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "KEGG:R09117"^^xsd:string) Annotation( ) "9alpha-copalyl-diphosphate diphosphate-lyase (9beta-pimara-7,15-diene-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "syn-pimara-7,15-diene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-4883"^^xsd:string) Annotation( "RHEA:25563"^^xsd:string) "Catalysis of the reaction: 9-alpha-copalyl diphosphate = 9-beta-pimara-7,15-diene + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-4884"^^xsd:string) Annotation( "RHEA:25539"^^xsd:string) "Catalysis of the reaction: ent-copalyl diphosphate = ent-sandaracopimara-8(14),15-diene + diphosphate."^^xsd:string) AnnotationAssertion( "ent-pimaradiene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R09120"^^xsd:string) Annotation( ) "ent-copalyl-diphosphate diphosphate-lyase [ent-sandaracopimara-8(14),15-diene-forming] activity"^^xsd:string) AnnotationAssertion(rdfs:label "ent-sandaracopimaradiene synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ent-isokaurene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17141283"^^xsd:string) "Catalysis of the reaction: ent-copalyl diphosphate = ent-isokaurene + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "KEGG:R09121"^^xsd:string) Annotation( ) "ent-copalyl-diphosphate diphosphate-lyase [ent-pimara-8(14),15-diene-forming] activity"^^xsd:string) AnnotationAssertion(rdfs:label "ent-pimara-8(14),15-diene synthase activity"^^xsd:string) AnnotationAssertion( "ent-pimaradiene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:25543"^^xsd:string) "Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-8(14),15-diene + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "syn-stemodene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:25559"^^xsd:string) "Catalysis of the reaction: 9-alpha-copalyl diphosphate = stemod-13(17)-ene + diphosphate."^^xsd:string) AnnotationAssertion( "exo-stemodene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R09116"^^xsd:string) Annotation( ) "9alpha-copalyl-diphosphate diphosphate-lyase [stemod-13(17)-ene-forming] activity"^^xsd:string) AnnotationAssertion( "stemodene synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "syn-stemod-13(17)-ene synthase activity"^^xsd:string) AnnotationAssertion( "stemod-13(17)-ene synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "holin activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jh2"^^xsd:string) Annotation( "PMID:1406491"^^xsd:string) "Catalysis of the temporally-regulated formation of a transmembrane protein hole that directly or indirectly allows murein hydrolyases to access their cell wall substrate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "canonical holin activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jh2"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:1406491"^^xsd:string) "Catalysis of the temporally-regulated formation of a non-specific transmembrane protein hole that allows release of a fully-folded phage-encoded endolysin (murein-degradase) from the cell."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jh2"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:1406491"^^xsd:string) "Catalysis of the temporally-regulated formation of a transmembrane protein hole that allows the passage of ions, causing a lethal, irreversible depolarization of the cell membrane."^^xsd:string) AnnotationAssertion(rdfs:label "pinholin activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:17914902"^^xsd:string) "Catalysis of the reaction: ATP + nicotinic acid riboside = ADP + nicotinic acid mononucleotide."^^xsd:string) AnnotationAssertion(rdfs:label "nicotinic acid riboside kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "acyl-CoA:alcohol O-acyltransferase activity"^^xsd:string) AnnotationAssertion( "AEATase activity"^^xsd:string) AnnotationAssertion( "acyl-coenzymeA:alcohol O-acyltransferase activity"^^xsd:string) AnnotationAssertion( "acyl-coenzymeA:ethanol O-acyltransferase activity"^^xsd:string) AnnotationAssertion( "acyl-CoA:ethanol O-acyltransferase"^^xsd:string) AnnotationAssertion( "alcohol acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of an acyl group to an oxygen atom on an alcohol acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "alcohol O-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:16361250"^^xsd:string) "Catalysis of the reaction: butanoyl-CoA + an alcohol = CoA + a butyl ester."^^xsd:string) AnnotationAssertion(rdfs:label "alcohol O-butanoyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:16361250"^^xsd:string) "Catalysis of the reaction: hexanoyl-CoA + an alcohol = CoA + a hexyl ester."^^xsd:string) AnnotationAssertion(rdfs:label "alcohol O-hexanoyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:16361250"^^xsd:string) "Catalysis of the reaction: octanoyl-CoA + an alcohol = CoA + an octyl ester."^^xsd:string) AnnotationAssertion(rdfs:label "alcohol O-octanoyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:16361250"^^xsd:string) "Catalysis of the reaction: decanoyl-CoA + an alcohol = CoA + a decyl ester."^^xsd:string) AnnotationAssertion(rdfs:label "alcohol O-decanoyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "O-butanoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a butyl group to an oxygen atom on the acceptor molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "O-hexanoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a hexyl group to an oxygen atom on the acceptor molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "O-decanoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a decyl group to an oxygen atom on the acceptor molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a butanoyl (CH3-[CH2]2-CO-) group to an acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "butanoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a hexanoyl (CH3-[CH2]4-CO-) group to an acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "hexanoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "decanoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a decanoyl (CH3-[CH2]8-CO-) group to an acceptor molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:10393192"^^xsd:string) "Interacting selectively and non-covalently with an RNA molecule that has assumed an incorrect conformation."^^xsd:string) AnnotationAssertion(rdfs:label "misfolded RNA binding"^^xsd:string) AnnotationAssertion( "RNA chaperone"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jp"^^xsd:string) "Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion, where the carboxylic chain has 8 or fewer carbon atoms."^^xsd:string) AnnotationAssertion( "butyrate esterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "short-chain carboxylesterase activity"^^xsd:string) AnnotationAssertion( "monobutyrase activity"^^xsd:string) AnnotationAssertion( "propionyl esterase activity"^^xsd:string) AnnotationAssertion( "methylbutyrase activity"^^xsd:string) AnnotationAssertion( "methylbutyrate esterase activity"^^xsd:string) AnnotationAssertion( "butyryl esterase activity"^^xsd:string) AnnotationAssertion( "short-chain esterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "interferon-lambda binding"^^xsd:string) AnnotationAssertion(rdfs:label "type III interferon binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "ISBN:0126896631"^^xsd:string) Annotation( "PMID:15546383"^^xsd:string) Annotation( "PMID:16734557"^^xsd:string) "Interacting selectively and non-covalently with a type III interferon. Interferon lambda is the only member of the type III interferon found so far."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type III interferon receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PR:000001362"^^xsd:string) "interferon-lambda receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0126896631"^^xsd:string) Annotation( "PMID:15546383"^^xsd:string) Annotation( "PMID:16734557"^^xsd:string) "Combining with a type III interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Interferon lambda is the only member of the type III interferon found so far."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA pyrophosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jh2"^^xsd:string) Annotation( "PMID:17612492"^^xsd:string) Annotation( "PMID:18202662"^^xsd:string) "Catalysis of the removal of a 5' terminal pyrophosphate from the 5'-triphosphate end of an RNA, leaving a 5'-monophosphate end."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "GABA-alpha-ketoglutaric acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "4-aminobutyrate-2-oxoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "gamma-aminobutyrate-alpha-ketoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "4-aminobutyrate-2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "GABA-alpha-ketoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "GABA-alpha-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "gamma-aminobutyrate-alpha-ketoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "gamma-aminobutyric acid-alpha-ketoglutaric acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "gamma-aminobutyric acid-2-oxoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "GABA-2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "GABA-oxoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "GABA-alpha-ketoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "gamma-aminobutyrate:alpha-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-aminobutyrate:2-oxoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "GABA-2-oxoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "4-aminobutanoate:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "gamma-aminobutyric acid-alpha-ketoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "4-aminobutyric acid 2-ketoglutaric acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "GABA-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "4-aminobutyrate-2-ketoglutarate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-aminobutyrate:pyruvate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: 4-aminobutanoate + pyruvate = succinate semialdehyde + alanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.19"^^xsd:string) "gamma-aminobutyric acid pyruvate transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.13"^^xsd:string) "2,3-diphosphoglycerate phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "bisphosphoglycerate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.13"^^xsd:string) "glycerate-2,3-diphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.13"^^xsd:string) Annotation( "EC:3.1.3.80"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:18413611"^^xsd:string) "Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = phosphoglycerate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.13"^^xsd:string) "2,3-bisphosphoglycerate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.13"^^xsd:string) "2,3-diphosphoglyceric acid phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.13"^^xsd:string) "diphosphoglycerate phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.80"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:18413611"^^xsd:string) "Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = 2-phospho-D-glycerate + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "bisphosphoglycerate 3-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.80"^^xsd:string) "2,3-bisphospho-D-glycerate 3-phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:18390652"^^xsd:string) "Catalysis of the reaction: L-2-hydroxyglutarate + O2 = 2-oxoglutarate + hydrogen peroxide."^^xsd:string) AnnotationAssertion(rdfs:label "L-2-hydroxyglutarate oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "AP(6)A hydrolase activity"^^xsd:string) AnnotationAssertion( "AP-6-A hydrolase activity"^^xsd:string) AnnotationAssertion( "diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10085096"^^xsd:string) Annotation( "PMID:9450008"^^xsd:string) "Catalysis of the reaction: P1-P6-bis(5'-adenosyl) hexaphosphate + H2O = AMP + adenosine 5'-pentaphosphate."^^xsd:string) AnnotationAssertion( "AP6A hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "bis(5'-adenosyl)-hexaphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "diadenosine 5',5'''-P1,P6-pentaphosphate hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "bis(5'-adenosyl)-pentaphosphatase activity"^^xsd:string) AnnotationAssertion( "AP5A hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10085096"^^xsd:string) Annotation( "PMID:9450008"^^xsd:string) "Catalysis of the reaction: P1-P6-bis(5'-adenosyl) pentaphosphate + H2O = AMP + adenosine 5'-tetraphosphate."^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Ap5a pyrophosphohydrolase activity"^^xsd:string) AnnotationAssertion( "AP(5)A hydrolase activity"^^xsd:string) AnnotationAssertion( "AP-5-A hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Enables the directed movement of a glycoprotein, any protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion(rdfs:label "glycoprotein transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mcc"^^xsd:string) Annotation( "PMID:10089879"^^xsd:string) Annotation( "PMID:17190603"^^xsd:string) "Catalysis of the reaction: ATP + ubiquitin + protein N-ubiquityl(n)lysine = AMP + diphosphate + protein N-ubiquityl(n+1)lysine. This reaction is the ligation of ubiquitin groups, via isopeptide bonds, to extend the length of the multiubiquitin chain attached to a substrate protein."^^xsd:string) AnnotationAssertion(rdfs:label "ubiquitin-ubiquitin ligase activity"^^xsd:string) AnnotationAssertion( "E4"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with any part of a dynactin complex; dynactin is a large protein complex that activates dynein-based motor activity."^^xsd:string) AnnotationAssertion(rdfs:label "dynactin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3' to 5' RNA helicase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3'-5' RNA helicase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the unwinding of an RNA helix in the direction 3' to 5'."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jp"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix in the direction 3' to 5'."^^xsd:string) AnnotationAssertion(rdfs:label "ATP-dependent 3'-5' RNA helicase activity"^^xsd:string) AnnotationAssertion( "ATP-dependent 3' to 5' RNA helicase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:18434318"^^xsd:string) "Catalysis of the reaction: a phosphatidylglycerol + H2O = 1,2-diacylglycerol + glycerol 3-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylglycerol phospholipase C activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phospholipase C, acting on phosphatidylcholine"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.3"^^xsd:string) "heat-labile hemolysin"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.3"^^xsd:string) "lipophosphodiesterase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.3"^^xsd:string) "Clostridium welchii alpha-toxin activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.3"^^xsd:string) "Clostridium oedematiens beta- and gamma-toxins activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.3"^^xsd:string) "phosphatidylcholine cholinephosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.3"^^xsd:string) "alpha-toxin"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.3"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: phosphatidylcholine + H2O = 1,2-diacylglycerol + a choline phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylcholine phospholipase C activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.17"^^xsd:string) Annotation( "EC:2.8.2.5"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin sulfate."^^xsd:string) AnnotationAssertion(rdfs:label "chondroitin sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:17227754"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 2'-O-sulfate. Results in sulfation of glucuronic acid and iduronic acid residues."^^xsd:string) AnnotationAssertion( "chondroitin 2-sulfotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "chondroitin 2-O-sulfotransferase activity"^^xsd:string) AnnotationAssertion( "chondroitin 2-O-sulphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + sulfated heparan sulfate."^^xsd:string) AnnotationAssertion(rdfs:label "heparan sulfate sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pf"^^xsd:string) "Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-3,4-bisphosphate + phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with U3 small nucleolar RNA."^^xsd:string) AnnotationAssertion(rdfs:label "U3 snoRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with box C/D small nucleolar RNA."^^xsd:string) AnnotationAssertion(rdfs:label "box C/D snoRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with box H/ACA small nucleolar RNA."^^xsd:string) AnnotationAssertion(rdfs:label "box H/ACA snoRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0772"^^xsd:string) "Catalysis of the reaction: 2-naphthaldehyde + NAD+ + H2O = 2-naphthoate + NADH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "2-naphthaldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0773"^^xsd:string) "Catalysis of the reaction: 1-naphthoic acid + NADH + O2 + H+ = cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene + NAD+."^^xsd:string) AnnotationAssertion(rdfs:label "1-naphthoic acid dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0774"^^xsd:string) "Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene = 1,2-dihydroxy-8-carboxynaphthalene + 2 H+ + 2 e-."^^xsd:string) AnnotationAssertion(rdfs:label "cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-formylsalicylate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0777"^^xsd:string) "Catalysis of the reaction: 3-formylsalicylic acid + O2 + H2O = 2-hydroxyisophthalic acid + hydrogen peroxide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxyisophthalate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0776"^^xsd:string) "Catalysis of the reaction: 2-hydroxyisophthalic acid = salicylate + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0787"^^xsd:string) "Catalysis of the reaction: 1-naphthaldehyde + NAD+ + H2O = 1-naphthoic acid + NADH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "1-naphthaldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0788"^^xsd:string) "Catalysis of the reaction: 2-methylnaphthalene + NADH + O2 + H+ = 2-hydroxymethylnaphthalene + NAD+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "2-methylnaphthalene hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1,2-dihydroxy-8-carboxynaphthalene dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0790"^^xsd:string) "Catalysis of the reaction: 1,2-dihydroxy-8-carboxynaphthalene + O2 = 2-carboxy-2-hydroxy-8-carboxychromene."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-carboxy-2-hydroxy-8-carboxychromene isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0791"^^xsd:string) "Catalysis of the reaction: 2-carboxy-2-hydroxy-8-carboxychromene = 2-hydroxy-3-carboxybenzalpyruvate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0792"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-3-carboxybenzalpyruvate + H2O = 3-formylsalicylic acid + pyruvate."^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxy-3-carboxy-benzalpyruvate hydratase-aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0767"^^xsd:string) "Catalysis of the reaction: 4-hydroxymethylsalicylaldehyde + NAD+ + H2O = 4-hydroxymethylsalicylate + NADH + 2 H+."^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxymethylsalicyaldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxy-4-hydroxymethylbenzalpyruvate hydratase-aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0766"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-4-hydroxymethylbenzalpyruvate + H2O = pyruvate + 4-hydroxymethylsalicylaldehyde."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxy-7-hydroxymethylchromene-2-carboxylate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0765"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate = 2-hydroxy-4-hydroxymethylbenzalpyruvate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0764"^^xsd:string) "Catalysis of the reaction: 1,2-dihydroxy-7-hydroxymethylnaphthalene + O2 = 2-hydroxy-7-hydroxymethylchromene-2-carboxylate."^^xsd:string) AnnotationAssertion(rdfs:label "1,2-dihydroxy-7-hydroxymethylnaphthalene dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0795"^^xsd:string) "Catalysis of the reaction: 1-methylnaphthalene + NADH + H+ + O2 = 1-hydroxymethylnaphthalene + NAD+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "1-methylnaphthalene hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0781"^^xsd:string) "Catalysis of the reaction: 1,2-dihydroxy-8-methylnaphthalene + O2 = 2-hydroxy-8-methylchromene-2-carboxylate + H+."^^xsd:string) AnnotationAssertion(rdfs:label "1,2-dihydroxy-8-methylnaphthalene dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0782"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-8-methylchromene-2-carboxylate = 2-hydroxy-3-methylbenzalpyruvate."^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxy-8-methylchromene-2-carboxylate isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxy-3-methylbenzalpyruvate hydratase-aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0783"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-3-methylbenzalpyruvate + H2O = pyruvate + 3-methylsalicylaldehyde."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0784"^^xsd:string) "Catalysis of the reaction: 3-methylsalicylaldehyde + NAD+ = 3-methylsalicylate + NADH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "3-methylsalicylaldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0821"^^xsd:string) "Catalysis of the reaction: 3,3',5,5'-tetrabromobisphenol A + 2 H+ + 2 e- = 3,3',5-tribromobisphenol A + HBr."^^xsd:string) AnnotationAssertion(rdfs:label "3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-monobromobisphenol A reductive dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0824"^^xsd:string) "Catalysis of the reaction: 3-monobromobisphenol A + 2 H+ + 2 e- = bisphenol A + HBr."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dimethylarsinite methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0806"^^xsd:string) "Catalysis of the reaction: dimethylarsenous acid + R2S-CH3 = trimethylarsine oxide + R2SH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "trimethylarsine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0807"^^xsd:string) "Catalysis of the reaction: trimethylarsine oxide + 2 H+ + 2 e- = trimethylarsine + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5-aminosalicylate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0809"^^xsd:string) "Catalysis of the reaction: 5-aminosalicylate + O2 = cis-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0810"^^xsd:string) "Catalysis of the reaction: trans-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate + H2O = fumarylpyruvate + NH3."^^xsd:string) AnnotationAssertion(rdfs:label "trans-ACOHDA hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0811"^^xsd:string) "Catalysis of the reaction: fumarylpyruvate + H2O = fumarate + pyruvate + H+."^^xsd:string) AnnotationAssertion(rdfs:label "fumarylpyruvate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0819"^^xsd:string) "Catalysis of the reaction: 2,4-dichloroaniline + 2 H+ + 2 e- = 4-chloroaniline + HCl."^^xsd:string) AnnotationAssertion(rdfs:label "2,4-dichloroaniline reductive dehalogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-cyclopropylmelamine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0825"^^xsd:string) "Catalysis of the reaction: cyromazine + H2O = N-cyclopropylammeline + NH3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0826"^^xsd:string) "Catalysis of the reaction: N-cyclopropylammeline + H2O = N-cyclopropylammelide + NH3."^^xsd:string) AnnotationAssertion(rdfs:label "N-cyclopropylammeline deaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0827"^^xsd:string) "Catalysis of the reaction: N-cyclopropylammelide + H2O = cyclopropylamine + cyanuric acid."^^xsd:string) AnnotationAssertion(rdfs:label "N-cyclopropylammelide alkylamino hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0838"^^xsd:string) "Catalysis of the reaction: dimethylarsinate + 3 H+ + 2 e- = dimethylarsinous acid + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "dimethylarsinate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3,3',5-tribromobisphenol A reductive dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0842"^^xsd:string) "Catalysis of the reaction: 3,3',5-tribromobisphenol A + 2 H+ + 2 e- = 3,3'-dibromobisphenol A + HBr."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3,3'-dibromobisphenol A reductive dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0844"^^xsd:string) "Catalysis of the reaction: 3,3'-dibromobisphenol A + 2 H+ + 2 e- = 3-monobromobisphenol A + HBr."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0849"^^xsd:string) "Catalysis of the reaction: o-nitrobenzoate + NADPH + H+ = o-hydroxylaminobenzoate + NADP+."^^xsd:string) AnnotationAssertion(rdfs:label "nitrobenzoate nitroreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxylaminobenzoate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0850"^^xsd:string) "o-hydroxylaminobenzoate nitroreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8848"^^xsd:string) "Catalysis of the reaction: 2-hydroxylaminobenzoate + NAD(P)H = anthranilate + NAD(P)+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0859"^^xsd:string) "Catalysis of the reaction: pertechnetate ion + 3/2 H2 = technetium (IV) oxide + H2O + OH-."^^xsd:string) AnnotationAssertion(rdfs:label "technetium (VII) reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0860"^^xsd:string) "Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 1,2-bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "bisphenol A hydroxylase B activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bisphenol A hydroxylase A activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0861"^^xsd:string) "Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 2,2-bis(4-hydroxyphenyl)-1-propanol + NAD+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0862"^^xsd:string) "Catalysis of the reaction: 1,2-bis(4-hydroxyphenyl)-2-propanol = 4,4'-dihydroxy-alpha-methylstilbene + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "1,2-bis(4-hydroxyphenyl)-2-proponol dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0864"^^xsd:string) "Catalysis of the reaction: 2,2-bis(4-hydroxyphenyl)-1-propanol + NADH + H+ + O2 = 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + NAD+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0867"^^xsd:string) "Catalysis of the reaction: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + O2 = 4-hydroxyphenacyl alcohol + 4-hydroxybenzoate + 2 H+ + 2 e-."^^xsd:string) AnnotationAssertion(rdfs:label "2,3-bis(4-hydroxyphenyl)-1,2-propanediol dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4,4'-dihydroxy-alpha-methylstilbene dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0866"^^xsd:string) "Catalysis of the reaction: 4,4'-dihydroxy-alpha-methylstilbene + O2 = 4-hydroxybenzaldehyde + 4-hydroxyacetophenone + 2 H+ + 2 e-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0872"^^xsd:string) "Catalysis of the reaction: 1-nitro-1,2-dihydro-1,3,5-triazine + 2 H2O = 1-nitro-1,3,5-triazinane-2,4-diol."^^xsd:string) AnnotationAssertion(rdfs:label "1-nitro-1,2-dihydro-1,3,5-triazine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chromate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0884"^^xsd:string) "Catalysis of the reaction: chromate = chromium (III)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0892"^^xsd:string) "Catalysis of the reaction: isoproturon + H2O = formaldehyde + monodemethylisoproturon + 2 H+ + 2 e-."^^xsd:string) AnnotationAssertion(rdfs:label "isoproturon dimethylaminedehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0893"^^xsd:string) "Catalysis of the reaction: monodemethylisoproturon + H2O = hydroxymonodemethylisoproturon + 2 H+ + 2 e-."^^xsd:string) AnnotationAssertion(rdfs:label "monodemethylisoproturon dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroxymonomethylisoproturon dimethylaminedehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0894"^^xsd:string) "Catalysis of the reaction: hydroxymonodemethylisoproturon + H2O = formaldehyde + 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0895"^^xsd:string) "Catalysis of the reaction: 4'-(2-hydroxyisopropyl)phenylurea + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + carbamic acid."^^xsd:string) AnnotationAssertion(rdfs:label "4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "monodemethylisoproturon dimethylaminedehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0897"^^xsd:string) "Catalysis of the reaction: monodemethylisoproturon + H2O = didemethylisoproturon + formaldehyde + 2 H+ + 2 e-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0898"^^xsd:string) "Catalysis of the reaction: didemethylisoproturon + H2O = carbamic acid + 4-isopropylaniline."^^xsd:string) AnnotationAssertion(rdfs:label "didemethylisoproturon amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "didemethylisoproturon dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0899"^^xsd:string) "Catalysis of the reaction: didemethylisoproturon + H2O = 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-isopropylaniline dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0901"^^xsd:string) "Catalysis of the reaction: 4-isopropylaniline + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + 2 H+ + 2 e-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-isopropylacetanilide amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0913"^^xsd:string) "Catalysis of the reaction: N-isopropylacetanilide + OH- = N-isopropylaniline + acetate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-isopropylacetaniline monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0914"^^xsd:string) "Catalysis of the reaction: N-isopropylacetanilide + 1/2 O2 = acetanilide + acetone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "limonene 8-hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0916"^^xsd:string) "Catalysis of the reaction: limonene + H2O = alpha-terpineol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(1-methylpentyl)succinate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0920"^^xsd:string) "Catalysis of the reaction: fumarate + n-hexane = (1-methylpentyl)succinate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0924"^^xsd:string) "Catalysis of the reaction: 4-methyloctanoyl-CoA = 4-methyloct-2-enoyl-CoA + 2 H+ + 2 e-."^^xsd:string) AnnotationAssertion(rdfs:label "4-methyloctanoyl-CoA dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-methyloct-2-enoyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0925"^^xsd:string) "Catalysis of the reaction: 4-methyloct-2-enoyl-CoA + H2O = 3-hydroxy-4-methyloctanoyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0926"^^xsd:string) "Catalysis of the reaction: 3-hydroxy-4-methyloctanoyl-CoA = 4-methyl-3-oxooctanoyl-CoA + 2 H+ + 2 e-."^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "21U-RNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kmv"^^xsd:string) "Interacting selectively and non-covalently with a 21U-RNA, a 21-nucleotide RNA characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "piRNA binding"^^xsd:string) AnnotationAssertion( "Piwi-associated RNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kmv"^^xsd:string) "Interacting selectively and non-covalently with a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "4-hydroxyproline transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:14502423"^^xsd:string) "Catalysis of the transfer of L-hydroxyproline from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "L-hydroxyproline transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: phosphatidylinositol bisphosphate + H2O = phosphatidylinositol phosphate + phosphate."^^xsd:string) AnnotationAssertion( "phosphatidylinositol-bisphosphatase activity"^^xsd:string) AnnotationAssertion( "triphosphoinositide phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol bisphosphate phosphatase activity"^^xsd:string) AnnotationAssertion( "diphosphoinositide phosphatase activity"^^xsd:string) AnnotationAssertion( "phosphatidyl-inositol-bisphosphate phosphatase activity"^^xsd:string) AnnotationAssertion( "triphosphoinositide phosphomonoesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: phosphatidylinositol trisphosphate + H2O = phosphatidylinositol bisphosphate + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol trisphosphate phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) "Catalysis of the removal of the 5-phosphate group of a phosphatidylinositol phosphate."^^xsd:string) AnnotationAssertion( "polyphosphoinositol lipid 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "phosphoinositide 5-phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol phosphate 5-phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidylinositol phosphate 4-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "phosphoinositide 4-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the removal of the 4-phosphate group of a phosphatidylinositol phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.66"^^xsd:string) "inositol polyphosphate 4-phosphatase type II activity"^^xsd:string) AnnotationAssertion( "1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 4-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate."^^xsd:string) AnnotationAssertion( "phosphatidyl-myo-inositol-4,5-bisphosphate 4-phosphohydrolase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:17303758"^^xsd:string) Annotation( "PMID:18084305"^^xsd:string) "Catalysis of the removal of the phosphate group from phosphothreonine by cleavage of the C-OP bond with the concomitant abstraction of the alpha proton, generating a double bond-containing product."^^xsd:string) AnnotationAssertion(rdfs:label "phosphothreonine lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxoglutarate dehydrogenase [NAD(P)+] activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + CoA + NAD(P)+ = succinyl-CoA + CO2 + NAD(P)H."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxoglutarate dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + CoA + NAD+ = succinyl-CoA + CO2 + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: pyruvate + CoA + NAD(P)+ = acetyl-CoA + CO2 + NAD(P)H."^^xsd:string) AnnotationAssertion(rdfs:label "pyruvate dehydrogenase [NAD(P)+] activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyruvate dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: pyruvate + CoA + NAD+ = acetyl-CoA + CO2 + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "DNA oligonucleotidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oligodeoxyribonucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the exonucleolytic cleavage of oligodeoxyribonucleotides to yield deoxyribonucleoside 5'-phosphates."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oligoribonucleotidase activity"^^xsd:string) AnnotationAssertion( "RNA oligonucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the exonucleolytic cleavage of oligoribonucleotides to yield ribonucleoside 5'-phosphates."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:15372"^^xsd:string) Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Interacting selectively and non-covalently with a tetrahydrobiopterin, 5,6,7,8-tetrahydrobiopterin or a derivative thereof; tetrahydrobiopterins are enzyme cofactors that carry electrons in redox reactions."^^xsd:string) AnnotationAssertion( "H4biopterin binding"^^xsd:string) AnnotationAssertion( "sapropterin binding"^^xsd:string) AnnotationAssertion(rdfs:label "tetrahydrobiopterin binding"^^xsd:string) AnnotationAssertion( "BH4 binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "aminopentanoic acid binding"^^xsd:string) AnnotationAssertion(rdfs:label "arginine binding"^^xsd:string) AnnotationAssertion( "Arg binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:29016"^^xsd:string) Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Interacting selectively and non-covalently with 2-amino-5-(carbamimidamido)pentanoic acid."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "vitamin A1 transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "Enables the directed movement of retinol into, out of or within a cell, or between cells. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A."^^xsd:string) AnnotationAssertion(rdfs:label "retinol transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutathione transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Enables the directed movement of glutathione, the tripeptide glutamylcysteinylglycine, across a membrane into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-amino acid efflux permease activity"^^xsd:string) AnnotationAssertion( "L-amino acid export transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-amino acid efflux transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of an L-amino acid from the inside of the cell to the outside of the cell across a membrane."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:17550896"^^xsd:string) "Catalysis of the removal of a methyl group from trimethylated lysine at position 4 of the histone H3 protein."^^xsd:string) AnnotationAssertion( "histone demethylase activity (H3-K4-me3 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone demethylase activity (H3-trimethyl-K4 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:17550896"^^xsd:string) "Catalysis of the removal of a methyl group from dimethylated lysine at position 4 of the histone H3 protein."^^xsd:string) AnnotationAssertion( "histone demethylase activity (H3-K4-me2 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone demethylase activity (H3-dimethyl-K4 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:16223729"^^xsd:string) "Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 4) + O2 + FAD + H2O = histone H3 L-lysine (position 4) + H2O2 + formaldehyde + FADH2. This reaction is the removal of a methyl group from monomethylated lysine at position 4 of the histone H3 protein."^^xsd:string) AnnotationAssertion( "histone demethylase activity (H3-K4-me1 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone demethylase activity (H3-monomethyl-K4 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "isopropylmalate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of isopropylmalate from one side of the membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) "Catalysis of the reaction: D-allulose 6-phosphate = D-fructose 6-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "allulose 6-phosphate 3-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of a tripeptide."^^xsd:string) AnnotationAssertion(rdfs:label "tripeptidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with an inhibin complex, a dimer of one inhibin-alpha subunit and one inhibin-beta subunit."^^xsd:string) AnnotationAssertion(rdfs:label "inhibin complex binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "inhibin monomer binding"^^xsd:string) AnnotationAssertion(rdfs:label "inhibin binding"^^xsd:string) AnnotationAssertion( "inhibin beta-A binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with an inhibin monomer, any of the polypeptides that combine to form activin and inhibin dimers."^^xsd:string) AnnotationAssertion( "inhibin beta-B binding"^^xsd:string) AnnotationAssertion( "inhibin alpha binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "saxophone binding"^^xsd:string) AnnotationAssertion( "sax ligand"^^xsd:string) AnnotationAssertion(rdfs:label "type I transforming growth factor beta receptor binding"^^xsd:string) AnnotationAssertion( "tkv ligand"^^xsd:string) AnnotationAssertion( "thickveins binding"^^xsd:string) AnnotationAssertion( "saxophone ligand"^^xsd:string) AnnotationAssertion( "transforming growth factor beta ligand binding to type I receptor"^^xsd:string) AnnotationAssertion( "TGF-beta type I binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a type I transforming growth factor beta receptor."^^xsd:string) AnnotationAssertion( "sax binding"^^xsd:string) AnnotationAssertion( "babo ligand"^^xsd:string) AnnotationAssertion( "tkv binding"^^xsd:string) AnnotationAssertion( "baboon ligand"^^xsd:string) AnnotationAssertion( "type I TGF-beta binding"^^xsd:string) AnnotationAssertion( "baboon receptor ligand"^^xsd:string) AnnotationAssertion( "babo binding"^^xsd:string) AnnotationAssertion( "transforming growth factor beta receptor type I binding"^^xsd:string) AnnotationAssertion( "thickveins ligand"^^xsd:string) AnnotationAssertion( "baboon binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "betaglycan binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a type III transforming growth factor beta receptor."^^xsd:string) AnnotationAssertion( "transforming growth factor beta ligand binding to type III receptor"^^xsd:string) AnnotationAssertion( "TGF-beta type III binding"^^xsd:string) AnnotationAssertion( "transforming growth factor beta receptor type III binding"^^xsd:string) AnnotationAssertion(rdfs:label "type III transforming growth factor beta receptor binding"^^xsd:string) AnnotationAssertion( "type IIII TGF-beta binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.4.19.9"^^xsd:string) "gamma-glutamyl hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.19.9"^^xsd:string) Annotation( "MEROPS_fam:C26"^^xsd:string) "Catalysis of the cleavage of a gamma-linked glutamate bond."^^xsd:string) AnnotationAssertion(rdfs:label "gamma-glutamyl-peptidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.26"^^xsd:string) "ACAT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.26"^^xsd:string) "cholesteryl ester synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.26"^^xsd:string) "acyl-CoA:cholesterol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.26"^^xsd:string) "acyl-CoA:cholesterol acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cholesterol O-acyltransferase activity"^^xsd:string) AnnotationAssertion( "acylcoenzyme A:cholesterol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.26"^^xsd:string) "acyl coenzyme A-cholesterol-O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.26"^^xsd:string) "cholesterol acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.26"^^xsd:string) Annotation( "RHEA:17732"^^xsd:string) "Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.26"^^xsd:string) "cholesterol ester synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: acyl-CoA + ergosterol = CoA + ergosterol ester."^^xsd:string) AnnotationAssertion(rdfs:label "ergosterol O-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lanosterol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: acyl-CoA + lanosterol = CoA + lanosterol ester."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone deacetylase activity (H4-K16 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.17"^^xsd:string) Annotation( "EC:3.5.1.98"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) Annotation( "RHEA:24551"^^xsd:string) "Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(E)-beta-ocimene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12624761"^^xsd:string) "Catalysis of the reaction: geranyl diphosphate = (E)-beta-ocimene + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1003"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA = 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + 2 H+ + 2 e-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1004"^^xsd:string) "Catalysis of the reaction: 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + H2O = 3-isopropenylpimelyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0073"^^xsd:string) "Catalysis of the reaction: glyphosate + OH- = glyoxylate + aminomethylphosphonic acid + H+ + 2 e-."^^xsd:string) AnnotationAssertion(rdfs:label "glyphosate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-cyclohexylformamide amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1030"^^xsd:string) "Catalysis of the reaction: N-cyclohexylformamide + OH- = cyclohexylamine + formate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1031"^^xsd:string) "Catalysis of the reaction: dimethylmalonate + H+ = isobutyrate + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "dimethylmalonate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pivalate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1032"^^xsd:string) "Catalysis of the reaction: pivalate + H+ + HSCoA + ATP = pivalyl-CoA + PPi + AMP."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1033"^^xsd:string) "Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "pivalyl-CoA mutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1034"^^xsd:string) "Catalysis of the reaction: salicylate + O2 + NAD(P)H + H+ = gentisate + H2O + NAD(P)+."^^xsd:string) AnnotationAssertion(rdfs:label "salicylate 5-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1039"^^xsd:string) "Catalysis of the reaction: 9-fluorenone + O2 + 2 H+ + 2 e- = 1-hydro-1,1a-dihydroxy-9-fluorenone."^^xsd:string) AnnotationAssertion(rdfs:label "9-fluorenone-3,4-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1-hydro-1,1a-dihydroxy-9-fluorenone dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1040"^^xsd:string) "Catalysis of the reaction: 1-hydro-1,1a-dihydroxy-9-fluorenone + H2O = 2,3-dihydroxy-2'-carboxybiphenyl + 3 H+ + 2 e-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,3-dihydroxy-2'-carboxybiphenyl 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1041"^^xsd:string) "Catalysis of the reaction: 2,3-dihydroxy-2'-carboxybiphenyl + O2 = 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1042"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + phthalate + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1043"^^xsd:string) "Catalysis of the reaction: (+)-(3S,4R)-cis-3,4-dihydroxy-3,4-dihydrofluorene = 3,4-dihydroxyfluorene + 2 H+ + 2 e-."^^xsd:string) AnnotationAssertion(rdfs:label "3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "isobutylamine N-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1053"^^xsd:string) "Catalysis of the reaction: isobutylamine + NADPH + O2 = isobutylhydroxylamine + NADP+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hypophosphite dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1058"^^xsd:string) "Catalysis of the reaction: hypophosphite + 2-oxoglutarate + O2 = succinate + phosphite + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1056"^^xsd:string) "Catalysis of the reaction: cyclopropanecarboxylate + CoASH = cyclopropanecarboxyl-CoA + OH-."^^xsd:string) AnnotationAssertion(rdfs:label "cyclopropanecarboxylate-CoA ligase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1057"^^xsd:string) "Catalysis of the reaction: cyclopropanecarboxyl-CoA = crotonoyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "cyclopropanecarboxyl-CoA decyclase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1059"^^xsd:string) "Catalysis of the reaction: cyclohexane + O2 + NAD(P)H + H+ = cyclohexanol + NAD(P)+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8697"^^xsd:string) "cyclohexane hydroxylase activity"^^xsd:string) AnnotationAssertion( "butane monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyclohexane monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1060"^^xsd:string) "Catalysis of the reaction: adipate + CoASH = adipyl-CoA + OH-."^^xsd:string) AnnotationAssertion(rdfs:label "adipate-CoA ligase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fosfomycin 2-glutathione ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1073"^^xsd:string) "Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + glutathione = hydrogen (1R,2R)-1-glutathio-2-hydroxypropylphosphonic acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fosfomycin 2-L-cysteine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1074"^^xsd:string) "Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + L-cysteine = hydrogen (1R,2R)-1-L-cysteine-2-hydroxypropylphosphonic acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dihydride TNP tautomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1070"^^xsd:string) "Catalysis of the reaction: TNP dihydride Meisenheimer complex (aci form) = TNP dihydride Meisenheimer complex (nitro form)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2,4,6-trinitrophenol dihydride denitratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trinitrophenol dihydride denitratase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1067"^^xsd:string) "Catalysis of the reaction: trinitrophenol dihydride Meisenheimer complex (aci form) = 2,4-dinitrophenol hydride Meisenheimer complex + NO2. Trinitrophenol is also known as TNP and dinitrophenol is also known as DNP."^^xsd:string) AnnotationAssertion( "TNP dihydride denitratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,4-dinitrocyclohexanone hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1069"^^xsd:string) "Catalysis of the reaction: 2,4-dinitrocyclohexanone + OH- = 4,6-dinitrohexanoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1079"^^xsd:string) "Catalysis of the reaction: branched-chain dodecylbenzene sulfonate + 1/2 O2 + H+ = sulfurous acid + branched-chain dodecyl-4-hydroxy-benzene + sulfite."^^xsd:string) AnnotationAssertion(rdfs:label "branched-chain dodecylbenzene sulfonate monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-hydroxy-2-naphthoate 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1104"^^xsd:string) "Catalysis of the reaction: 3-hydroxy-2-naphthoate + O2 = (3E)-3-[(6Z)-6-(carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1119"^^xsd:string) "Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-11,12-epoxide."^^xsd:string) AnnotationAssertion(rdfs:label "benzo(a)pyrene 11,12-epoxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1121"^^xsd:string) "Catalysis of the reaction: benzo(a)pyrene-trans-11,12-dihydrodiol = 11,12-dihydroxybenzo(a)pyrene + 2 H+ + 2 e-."^^xsd:string) AnnotationAssertion(rdfs:label "benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "benzo(a)pyrene 11,12-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1124"^^xsd:string) "Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-11,12-dihydrodiol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4,5-dihydroxybenzo(a)pyrene methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1131"^^xsd:string) "Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + C1 unit = hydroxymethoxybenzo(a)pyrene."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1126"^^xsd:string) "Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-4,5-dihydrodiol."^^xsd:string) AnnotationAssertion(rdfs:label "benzo(a)pyrene 4,5-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1127"^^xsd:string) "Catalysis of the reaction: benzo(a)pyrene-cis-4,5-dihydrodiol = 4,5-dihydroxybenzo(a)pyrene + H2."^^xsd:string) AnnotationAssertion(rdfs:label "benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4,5-dihydroxybenzo(a)pyrene dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1128"^^xsd:string) "Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + O2 = 4,5-chrysenedicarboxylate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1132"^^xsd:string) "Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-9,10-dihydrodiol."^^xsd:string) AnnotationAssertion(rdfs:label "benzo(a)pyrene 9,10-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "9,10-dihydroxybenzo(a)pyrene dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1134"^^xsd:string) "Catalysis of the reaction: 9,10-dihydroxybenzo(a)pyrene + O2 = cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:1137"^^xsd:string) "Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-7,8-dihydrodiol."^^xsd:string) AnnotationAssertion(rdfs:label "benzo(a)pyrene 7,8-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1138"^^xsd:string) "Catalysis of the reaction: benzo(a)pyrene-cis-7,8-dihydrodiol + O2 = cis-4-(7-hydroxypyren-8-yl)-2-oxobut-3-enoate."^^xsd:string) AnnotationAssertion(rdfs:label "7,8-dihydroxy benzo(a)pyrene dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1135"^^xsd:string) "Catalysis of the reaction: cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate = 10-oxabenzo(def)chrysen-9-one + formate + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "anthracene 9,10-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1141"^^xsd:string) "Catalysis of the reaction: anthracene + 2 H2O = cis-9,10-dihydroanthracene-9,10-diol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1144"^^xsd:string) "Catalysis of the reaction: cis-9,10-dihydroanthracene-9,10-diol = 9,10-anthraquinone + 4 H+ + 4 e-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ADD 9alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1149"^^xsd:string) "Catalysis of the reaction: androsta-1,4-diene-3,17-dione + reduced ferredoxin + O2 = 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + H2O + oxidized ferredoxin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1150"^^xsd:string) "Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADPH + H+ + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADP+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "3-HSA hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4,9-DSHA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1152"^^xsd:string) "Catalysis of the reaction: (3E,1Z)-4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate + H2O = (2E,4E)-2-hydroxyhexa-2,4-dienoate + 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "citronellol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1155"^^xsd:string) "Catalysis of the reaction: citronellol + NAD+ = citronellal + NADH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "citronellal dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1156"^^xsd:string) "Catalysis of the reaction: citronellal + NAD+ + OH- = citronellate + NADH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1157"^^xsd:string) "Catalysis of the reaction: citronellate + CoASH + ATP = citronellyl-CoA + AMP + PPi."^^xsd:string) AnnotationAssertion(rdfs:label "citronellyl-CoA ligase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "citronellyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1159"^^xsd:string) "Catalysis of the reaction: citronellyl-CoA + NAH+ = cis-geranyl-CoA + NADH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1169"^^xsd:string) "Catalysis of the reaction: tetralin + O2 + NADH + H+ = cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+."^^xsd:string) AnnotationAssertion(rdfs:label "tetralin ring-hydroxylating dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1170"^^xsd:string) "Catalysis of the reaction: cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+ = 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + NADH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "1,2-dihydroxy-1,2,5,6,7,8-hexyhadronaphthalene dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1171"^^xsd:string) "Catalysis of the reaction: 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + O2 = 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H+."^^xsd:string) AnnotationAssertion(rdfs:label "1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1172"^^xsd:string) "Catalysis of the reaction: 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H2O = 2-hydroxydec-2,4-diene-1,10-dioate + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxydec-2,4-diene-1,10-dioate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1172"^^xsd:string) "Catalysis of the reaction: 2-hydroxydec-2,4-diene-1,10-dioate + H2O = (2Z)-2,4-dihydroxydec-2-enedioate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1174"^^xsd:string) "Catalysis of the reaction: (2Z)-2,4-dihydroxydec-2-enedioate = pyruvate + 7-oxoheptanoate."^^xsd:string) AnnotationAssertion(rdfs:label "(2Z)-2,4-dihydroxydec-2-enedioate aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1176"^^xsd:string) "Catalysis of the reaction: (R)-1,2,3,4-tetrahydronaphthol = 1,2,3,4-tetrahydronaphthalone + 2 H+ + 2 e-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "geranial dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1164"^^xsd:string) "Catalysis of the reaction: geranial + NAD+ + OH- = geranylate + NADH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "geranylate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1165"^^xsd:string) "Catalysis of the reaction: geranylate + CoASH = trans-geranyl-CoA + OH-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1177"^^xsd:string) "Catalysis of the reaction: 2-mercaptobenzothiazole + O2 + 2 H+ + 2 e- = 2-mercaptobenzothiazole-cis-6,7-dihydrodiol."^^xsd:string) AnnotationAssertion(rdfs:label "2-mercaptobenzothiazole dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-mercaptobenzothiazole monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1178"^^xsd:string) "Catalysis of the reaction: 2-mercaptobenzothiazole + 1/2 O2 = 6-hydroxy-2-mercaptobenzothiazole."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "6-hydroxy-2-mercaptobenzothiazole monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1181"^^xsd:string) "Catalysis of the reaction: 6-hydroxy-2-mercaptobenzothiazole + 1/2 O2 = 6,7-dihydroxy-2-mercaptobenzothiazole."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-mercaptobenzothiazole-cis-6,7-dihydrodiol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1179"^^xsd:string) "Catalysis of the reaction: 2-mercaptobenzothiazole-cis-6,7-dihydrodiol = 6,7-dihydroxy-2-mercaptobenzothiazole + 2 H+ + 2 e-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1183"^^xsd:string) "Catalysis of the reaction: (-)-(2S,5R)-menthone + NAD+ = (5R)-menth-2-enone + NADH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "menthone dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1184"^^xsd:string) "Catalysis of the reaction: (5R)-menth-2-enone + H2O = (5R)-3-hydroxymenthone."^^xsd:string) AnnotationAssertion(rdfs:label "menth-2-enone hydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1185"^^xsd:string) "Catalysis of the reaction: (5R)-3-hydroxymenthone + NAD+ = mentha-1,3-dione + NADH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxymenthone dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1186"^^xsd:string) "Catalysis of the reaction: mentha-1,3-dione + CoASH = 3,7-dimethyl-5-oxo-octyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "mentha-1,3-dione-CoA ligase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thiophene-2-carboxylate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1234"^^xsd:string) "Catalysis of the reaction: thiophene-2-carboxylate + ATP + CoASH = thiophene-2-carboxyl-CoA + AMP + PPi."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1238"^^xsd:string) "Catalysis of the reaction: 2-oxoglutaryl-CoA + OH- = 2-oxoglutarate + CoASH."^^xsd:string) AnnotationAssertion(rdfs:label "2-oxoglutaryl-CoA thioesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "naphthyl-2-methyl-succinate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1256"^^xsd:string) "Catalysis of the reaction: naphthyl-2-methyl-succinate + succinyl-CoA = naphthyl-2-methyl-succinyl-CoA + succinate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "naphthyl-2-methyl-succinyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1258"^^xsd:string) "Catalysis of the reaction: naphthyl-2-methyl-succinyl-CoA = naphthyl-2-methylene-succinyl-CoA + 2 H+ + 2 e-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "naphthyl-2-methylene-succinyl-CoA lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1259"^^xsd:string) "Catalysis of the reaction: naphthyl-2-methylene-succinyl-CoA + H2O = naphthyl-2-hydroxymethyl-succinyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1260"^^xsd:string) "Catalysis of the reaction: naphthyl-2-hydroxymethyl-succinyl-CoA = naphthyl-2-oxomethyl-succinyl-CoA + 2 H+ + 2 e-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1261"^^xsd:string) "Catalysis of the reaction: naphthyl-2-oxomethyl-succinyl-CoA + CoASH = 2-naphthoyl-CoA + succinyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1262"^^xsd:string) "Catalysis of the reaction: 2-naphthoyl-CoA + OH- = 2-naphthoate + CoASH."^^xsd:string) AnnotationAssertion(rdfs:label "2-naphthoate CoA-transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1269"^^xsd:string) "Catalysis of the reaction: isooctane + 1/2 O2 = 2,4,4-trimethyl-1-pentanol."^^xsd:string) AnnotationAssertion(rdfs:label "isooctane monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1274"^^xsd:string) "Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + CoASH = pivalyl-CoA + propanoyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4,4-dimethyl-3-oxopentanal dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1309"^^xsd:string) "Catalysis of the reaction: 4,4-dimethyl-3-oxopentanal + H2O = 4,4-dimethyl-3-oxopentanoate + 3 H+ + 2 e-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,4,4-trimethyl-3-oxopentanoate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1278"^^xsd:string) "Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoate + H+ = 2,2-dimethyl-3-pentanone + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1280"^^xsd:string) "Catalysis of the reaction: 4,4-dimethyl-3-oxopentanoate + H+ = 3,3-dimethyl-2-butanone + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "4,4-dimethyl-3-oxopentanoate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1153"^^xsd:string) "Catalysis of the reaction: androst-4-ene-3,17-dione + O2 + 2 H+ + 2 e- = 9alpha-hydroxy-4-androstene-3,17-dione + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "4-AD 9alpha-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1281"^^xsd:string) "Catalysis of the reaction: (2E,4E)-2-hydroxyhexa-2,4-dienoate + H2O = 4-hydroxy-2-oxohexanoate."^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxyhexa-2,4-dienoate hydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-(methylthio)benzothiazole monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1287"^^xsd:string) "Catalysis of the reaction: 2-(methylthio)benzothiazole + 1/2 O2 = 2-(methylsulfinyl)benzothiazole."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1291"^^xsd:string) "Catalysis of the reaction: 2-hydroxybenzothiazole + 1/2 O2 = 2,6-dihydroxybenzothiazole."^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxybenzothiazole monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1292"^^xsd:string) "Catalysis of the reaction: benzothiazole + 1/2 O2 = 2-hydroxybenzothiazole."^^xsd:string) AnnotationAssertion(rdfs:label "benzothiazole monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-mercaptobenzothiazole desulfurase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1288"^^xsd:string) "Catalysis of the reaction: 2-mercaptobenzothiazole + reduced acceptor = benzothiazole + hydrogen sulfide + oxidized acceptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "benzothiazole-2-sulfonate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1290"^^xsd:string) "Catalysis of the reaction: benzothiazole-2-sulfonate + H2O = 2-hydroxybenzothiazole + HSO3-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1294"^^xsd:string) "Catalysis of the reaction: 2,6-dihydroxybenzothiazole + 1/2 O2 = 2,6,7-trihydroxybenzothiazole."^^xsd:string) AnnotationAssertion(rdfs:label "2,6-dihydroxybenzothiazole monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,4,4-trimethyl-1-pentanol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1270"^^xsd:string) "Catalysis of the reaction: 2,4,4-trimethyl-1-pentanol = 2,4,4-trimethylpentanal + 2 H+ + 2 e-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1275"^^xsd:string) "Catalysis of the reaction: 2,4,4-trimethylpentanal + H2O = 2,4,4-trimethylpentanoate + 3 H+ + 2 e-."^^xsd:string) AnnotationAssertion(rdfs:label "2,4,4-trimethylpentanal dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1271"^^xsd:string) "Catalysis of the reaction: 2,4,4-trimethylpentanoate + CoASH = 2,4,4-trimethylpentanoyl-CoA + OH-."^^xsd:string) AnnotationAssertion(rdfs:label "2,4,4-trimethylpentanoate-CoA ligase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1276"^^xsd:string) "Catalysis of the reaction: 2,4,4-trimethylpentanoyl-CoA = 2,4,4-trimethylpent-2-enoyl-CoA + 2 H+ + 2 e-."^^xsd:string) AnnotationAssertion(rdfs:label "2,4,4-trimethylpentanoyl-CoA dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,4,4-trimethylpent-2-enoyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1277"^^xsd:string) "Catalysis of the reaction: 2,4,4-trimethylpent-2-enoyl-CoA + H2O = 2,4,4-trimethyl-3-hydroxypentanoyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1273"^^xsd:string) "Catalysis of the reaction: 2,4,4-trimethyl-3-hydroxypentanoyl-CoA = 2,4,4-trimethyl-3-oxopentanoyl-CoA + 2 H+ + 2 e-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1307"^^xsd:string) "Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + OH- = 2,4,4-trimethyl-3-oxopentanoate + CoASH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pinacolone 5-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r12979"^^xsd:string) "Catalysis of the reaction: 2,2-dimethyl-3-pentanone + 1/2 O2 = 1-hydroxy-4,4-dimethylpentan-3-one."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1308"^^xsd:string) "Catalysis of the reaction: 1-hydroxy-4,4-dimethylpentan-3-one = 4,4-dimethyl-3-oxopentanal + 2 H+ + 2 e-."^^xsd:string) AnnotationAssertion(rdfs:label "1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "trans-geranyl-CoA isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1310"^^xsd:string) "Catalysis of the reaction: trans-geranyl-CoA = cis-geranyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thioacetamide S-oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1312"^^xsd:string) "Catalysis of the reaction: thioacetamide + O2 + 2 H+ + 2 e- = thioacetamide S-oxide + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1313"^^xsd:string) "Catalysis of the reaction: thioacetamide S-oxide + O2 + 2 H+ + 2 e- = thioacetamide S,S-dioxide + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "thioacetamide S-oxide S-oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "caffeine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1321"^^xsd:string) "Catalysis of the reaction: caffeine + O2 + 2 H+ + 2 e- = 1,3,7-trimethyluric acid + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "isonicotinic acid hydrazide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1336"^^xsd:string) "Catalysis of the reaction: isoniazid + H2O = isonicotinate + hydrazine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1337"^^xsd:string) "Catalysis of the reaction: isonicotinate + acceptor + H2O = 2-hydroxyisonicotinate + reduced acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "isonicotinate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1338"^^xsd:string) "Catalysis of the reaction: 2-hydroxyisonicotinate + acceptor + H2O = citrazinate + reduced acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxyisonicotinate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,3,6-trihydroxyisonicotinate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1340"^^xsd:string) "Catalysis of the reaction: 2,3,6-trihydroxyisonicotinate = 2,3,6-trihydroxypyridine + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "citrazinate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1339"^^xsd:string) "Catalysis of the reaction: citrazinate + H2O = 2,3,6-trihydroxyisonicotinate + 2 H+ + 2 e-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "citrazinate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1343"^^xsd:string) "Catalysis of the reaction: citrazinate + H2O = cis-aconitamide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1344"^^xsd:string) "Catalysis of the reaction: cis-aconitamide + H2O = cis-aconitate + HN3."^^xsd:string) AnnotationAssertion(rdfs:label "cis-aconitamide amidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1350"^^xsd:string) "Catalysis of the reaction: gamma-N-formylaminovinylacetate + H2O = gamma-aminovinylacetate + HCOOH."^^xsd:string) AnnotationAssertion(rdfs:label "gamma-N-formylaminovinylacetate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1351"^^xsd:string) "Catalysis of the reaction: gamma-aminovinylacetate + H2O = succinic semialdehyde + NH3."^^xsd:string) AnnotationAssertion(rdfs:label "gamma-aminovinylacetate deaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1382"^^xsd:string) "Catalysis of the reaction: endosulfan + O2 + 2 H+ + 2 e- = endosulfan sulfate + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "endosulfan monooxygenase I activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "endosulfan hemisulfate sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1384"^^xsd:string) "Catalysis of the reaction: endosulfan hemisulfate + H2O = endosulfan monoalcohol + 2 H+ + sulfate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "endosulfan diol hydrolyase (cyclizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1386"^^xsd:string) "Catalysis of the reaction: endosulfan diol = endosulfan ether + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1388"^^xsd:string) "Catalysis of the reaction: endosulfan diol = endosulfan hydroxyether + 2 H+ + 2 e-."^^xsd:string) AnnotationAssertion(rdfs:label "endosulfan diol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "endosulfan lactone lactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1389"^^xsd:string) "Catalysis of the reaction: endosulfan lactone + H2O = endosulfan hydroxycarboxylate + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-nitrodimethylamine hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1395"^^xsd:string) "Catalysis of the reaction: N-nitrodimethylamine + O2 + 2 H+ + 2 e- = N-nitromethylamine + formaldehyde + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-hydroxypyridine-3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1397"^^xsd:string) "Catalysis of the reaction: 4-hydroxypyridine + O2 + H+ + NADPH = pyridine-3,4-diol + H2O + NADP+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1398"^^xsd:string) "Catalysis of the reaction: pryidine-3,4-diol + O2 = 3-(N-formyl)-formiminopyruvate."^^xsd:string) AnnotationAssertion(rdfs:label "pyridine-3,4-diol dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-formiminopyruvate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1400"^^xsd:string) "Catalysis of the reaction: 3-formiminopyruvate + H2O = 3-formylpyruvate + HN3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1358"^^xsd:string) "Catalysis of the reaction: 4-(1-ethyl-1,4-dimethyl-pentyl)phenol + O2 + 2 H+ + 2 e- = hydroquinone + 3,6-dimethylheptan-3-ol."^^xsd:string) AnnotationAssertion(rdfs:label "4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hexadecyltrimethylammonium chloride monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1373"^^xsd:string) "Catalysis of the reaction: hexadecyltrimethylammonium chloride + NAD(P)H + H+ + O2 = trimethylamine + hexadecanal + NAD(P)+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.148"^^xsd:string) Annotation( "UM-BBD_reactionID:r1407"^^xsd:string) "Catalysis of the reaction: N,N,N-trimethylamine + NADPH + H+ + O2 = N,N,N-trimethylamine N-oxide + NADP+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "trimethylamine monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-(N-formyl)-formiminopyruvate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1399"^^xsd:string) "Catalysis of the reaction: 3-(N-formyl)-formiminopyruvate + H2O = 3-formiminopyruvate + formate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1411"^^xsd:string) "Catalysis of the reaction: endosulfan hydroxyether = endosulfan lactone + 2 H+ + 2 e-."^^xsd:string) AnnotationAssertion(rdfs:label "endosulfan hydroxyether dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1387"^^xsd:string) "Catalysis of the reaction: endosulfan sulfate + H2O = endosulfan diol + sulfite."^^xsd:string) AnnotationAssertion(rdfs:label "endosulfan sulfate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "endosulfan ether monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1413"^^xsd:string) "Catalysis of the reaction: endosulfan ether + O2 + 2 H+ + 2 e- = endosulfan hydroxyether + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5-chloro-2-oxopent-4-enoate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1436"^^xsd:string) "Catalysis of the reaction: 5-chloro-2-oxopent-4-enoate + H2O = 5-chloro-4-hydroxy-2-oxopentanate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5-chloro-4-hydroxy-2-oxopentanate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1437"^^xsd:string) "Catalysis of the reaction: 5-chloro-4-hydroxy-2-oxopentanate = pyruvate + chloroacetaldehyde."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0721"^^xsd:string) "Catalysis of the reaction: N-isopropylaniline + O2 + 2 H+ + NADH = catechol + NAD+ + isopropylamine."^^xsd:string) AnnotationAssertion(rdfs:label "N-isopropylaniline 1,2-dixoxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acetanilide 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0723"^^xsd:string) "Catalysis of the reaction: acetanilide + O2 + 2 H+ + NADH = catechol + NAD+ + acetamide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-chloro-N-isopropylacetanilide 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0724"^^xsd:string) "Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + O2 + 2 H+ + NADH = 2-chloro-N-isopropylacetamide + catechol + NAD+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1441"^^xsd:string) "Catalysis of the reaction: 6-hydroxypseudooxynicotine + H2O + OH- = 6-hydroxy-3-succinoylpyridine + 4 H+ + 4 e- + methylamine."^^xsd:string) AnnotationAssertion(rdfs:label "6-hydroxypseudooxynicotine dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1442"^^xsd:string) "Catalysis of the reaction: 6-hydroxy-3-succinoylpyridine + H2O = succinic semialdehyde + 2,5-dihydroxypyridine."^^xsd:string) AnnotationAssertion(rdfs:label "6-hydroxy-3-succinoylpyridine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phthalate 3,4-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1444"^^xsd:string) "Catalysis of the reaction: phthalate + O2 + NADH + H+ = phthalate 3,4-cis-dihydrodiol + NAD+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phthalate 3,4-cis-dihydrodiol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1445"^^xsd:string) "Catalysis of the reaction: phthalate 3,4-cis-dihydrodiol + NAD+ = 3,4-dihydroxyphthalate + NADH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2,4,6-trinitrophenol hydride denitratase activity"^^xsd:string) AnnotationAssertion( "TNP hydride denitratase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1448"^^xsd:string) "Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex = 2,4-dinitrophenol + nitrite. Trinitrophenol is also known as TNP."^^xsd:string) AnnotationAssertion(rdfs:label "trinitrophenol hydride denitratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-methylhexanoyl-CoA C-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0927"^^xsd:string) "Catalysis of the reaction: 4-methyl-3-oxooctanoyl-CoA + CoA = acetyl-CoA + 2-methylhexanoyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0928"^^xsd:string) "Catalysis of the reaction: 2-methylhexanoyl-CoA = 2-methylhex-2-enoyl-CoA + 2 H+ + e-."^^xsd:string) AnnotationAssertion(rdfs:label "2-methylhexanoyl-CoA dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-methylhex-2-enoyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0929"^^xsd:string) "Catalysis of the reaction: 2-methylhex-2-enoyl-CoA + H2O = 3-hydroxy-2-methylhexanoyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0930"^^xsd:string) "Catalysis of the reaction: 3-hydroxy-2-methylhexanoyl-CoA = 2-methyl-3-oxohexanoyl-CoA + 2 H+ + 2 e-."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "butyryl-CoA 2-C-propionyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0931"^^xsd:string) "Catalysis of the reaction: 2-methyl-3-oxohexanoyl-CoA + CoA = propanoyl-CoA + butyryl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0934"^^xsd:string) "Catalysis of the reaction: pyrene + 2 H+ + 2 e- + O2 = cis-4,5-dihydroxy-4,5-dihydropyrene."^^xsd:string) AnnotationAssertion(rdfs:label "pyrene dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0935"^^xsd:string) "Catalysis of the reaction: cis-4,5-dihydroxy-4,5-dihydropyrene = 4,5-dihydroxypyrene + 2 H+ + 2 e-."^^xsd:string) AnnotationAssertion(rdfs:label "cis-4,5-dihydroxy-4,5-dihydropyrene dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0936"^^xsd:string) "Catalysis of the reaction: 4,5-dihydroxypyrene + O2 = phenanthrene-4,5-dicarboxylate + 2 H+."^^xsd:string) AnnotationAssertion(rdfs:label "4,5-dihydroxypyrene dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0937"^^xsd:string) "Catalysis of the reaction: phenanthrene-4,5-dicarboxylate + H+ = phenanthrene-4-carboxylate + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "phenanthrene-4,5-dicarboxylate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cis-3,4-phenanthrenedihydrodiol-4-carboxylate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0940"^^xsd:string) "Catalysis of the reaction: cis-3,4-phenanthrenedihydrodiol-4-carboxylate = 3,4-dihydroxyphenanthrene + H+ + 2 e- + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyrene 4,5-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0941"^^xsd:string) "Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-4,5-oxide + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0942"^^xsd:string) "Catalysis of the reaction: pyrene-4,5-oxide + H2O = trans-4,5-dihydroxy-4,5-dihydropyrene."^^xsd:string) AnnotationAssertion(rdfs:label "pyrene-4,5-epoxide hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyrene 1,2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0943"^^xsd:string) "Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-1,2-oxide + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0946"^^xsd:string) "Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-6,7-oxide + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "1-hydroxypyrene 6,7-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0949"^^xsd:string) "Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-7,8-oxide + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "1-hydroxypyrene 7,8-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0952"^^xsd:string) "Catalysis of the reaction: 1-hydroxypyrene + XSO3- = 1-pyrenylsulfate + HX."^^xsd:string) AnnotationAssertion(rdfs:label "1-hydroxypyrene sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0953"^^xsd:string) "Catalysis of the reaction: 1-hydroxypyrene + XCH3 = 1-methoxypyrene + HX."^^xsd:string) AnnotationAssertion(rdfs:label "1-hydroxypyrene methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0954"^^xsd:string) "Catalysis of the reaction: 1-methoxypyrene + O2 + 2 H+ + 2 e- = 1-methoxypyrene-6,7-oxide + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "1-methoxypyrene 6,7-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1-hydroxy-6-methoxypyrene methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0956"^^xsd:string) "Catalysis of the reaction: 1-hydroxy-6-methoxypyrene + XCH3 = 1,6-dimethoxypyrene + HX."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0939"^^xsd:string) "Catalysis of the reaction: phenanthrene-4-carboxylate + 2 H+ + 2 e- + O2 = cis-3,4-phenanthrenedihydrodiol-4-carboxylate."^^xsd:string) AnnotationAssertion(rdfs:label "phenanthrene-4-carboxylate dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tetrachlorobenzene dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0957"^^xsd:string) "Catalysis of the reaction: 2,4-dichlorotoluene + NADH + H+ + O2 = 4,6-dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0959"^^xsd:string) "Catalysis of the reaction: 4,6-dichloro-3-methylcatechol + O2 = 3,5-dichloro-3-methyl-cis,cis-muconate + 2 H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0980"^^xsd:string) "Catalysis of the reaction: perchlorate + 2 H+ + 2 e- = chlorate + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "perchlorate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyrrole-2-carboxylate monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0968"^^xsd:string) "Catalysis of the reaction: pryrole-2-carboxylate + NADH + O2 + H+ = 5-hydroxypyrrole-2-carboxylate + NAD+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0969"^^xsd:string) "Catalysis of the reaction: 5-hydroxypyrrole-2-carboxylate = 5-oxo-4,5-dihydropyrrole-2-carboxylate."^^xsd:string) AnnotationAssertion(rdfs:label "5-hydroxypyrrole-2-carboxylate tautomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0984"^^xsd:string) "Catalysis of the reaction: 5-oxo-4,5-dihydropyrrole-2-carboxylate + 2 H2O = 2-oxoglutarate + NH3."^^xsd:string) AnnotationAssertion(rdfs:label "5-oxo-4,5-dihydropyrrole-2-carboxylate amidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0970"^^xsd:string) "Catalysis of the reaction: pryrole-2-carboxylate + H+ = pyrrole + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "pyrrole-2-carboxylate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0988"^^xsd:string) "Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = cis-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi."^^xsd:string) AnnotationAssertion(rdfs:label "cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0989"^^xsd:string) "Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = trans-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0986"^^xsd:string) "Catalysis of the reaction: 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA + NAD+ = 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + NADH+ + H+."^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0987"^^xsd:string) "Catalysis of the reaction: 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + CoASH = 3-isopropylbut-3-enoyl-CoA + propanoyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-isopropylbut-3-enoyl-CoA thioesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0994"^^xsd:string) "Catalysis of the reaction: 3-isopropylbut-3-enoyl-CoA + H2O = 3-isopropylbut-3-enoic acid + CoASH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0321"^^xsd:string) "Catalysis of the reaction: terephthalate + H2O = benzoate + HCO3-."^^xsd:string) AnnotationAssertion(rdfs:label "terephthalate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,6-dihydroxypseudooxynicotine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0482"^^xsd:string) "Catalysis of the reaction: 2,6-dihydroxypseudooxynicotine + H2O = 2,6-dihydroxypyridine + 4-methylaminobutyrate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1008"^^xsd:string) "Catalysis of the reaction: 1,1-dichloroethane + 2 H+ + 2 e- = chloroethane + HCl."^^xsd:string) AnnotationAssertion(rdfs:label "1,1-dichloroethane reductive dehalogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1020"^^xsd:string) "Catalysis of the reaction: phenylboronic acid + O2 + 2 H+ + 2 e- = phenol + B(OH)3."^^xsd:string) AnnotationAssertion(rdfs:label "phenylboronic acid monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1026"^^xsd:string) "Catalysis of the reaction: o-hydroxylaminobenzoate = 3-hydroxyanthranilate."^^xsd:string) AnnotationAssertion(rdfs:label "o-hydroxylaminobenzoate mutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0266"^^xsd:string) "Catalysis of the reaction: malonate semialdehyde + H+ = acetaldehyde + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "malonate semialdehyde decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1002"^^xsd:string) "Catalysis of the reaction: perillyl-CoA + H2O = 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "perillyl-CoA hydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1450"^^xsd:string) "Catalysis of the reaction: diphenyl ether + O2 = 2,3-dihydroxydiphenyl ether."^^xsd:string) AnnotationAssertion(rdfs:label "diphenyl ether 2,3-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,3-dihydroxydiphenyl ether dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1451"^^xsd:string) "Catalysis of the reaction: 2,3-dihydroxydiphenyl ether + O2 + H2O = 2-hydroxymuconate + phenol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1453"^^xsd:string) "Catalysis of the reaction: diphenyl ether + NADH + O2 + H+ = phenol + catechol + NAD+."^^xsd:string) AnnotationAssertion(rdfs:label "diphenyl ether 1,2-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1495"^^xsd:string) "Catalysis of the reaction: 3-nitrophenol + 2 NADH + 2 H+ = 3-hydroxyaminophenol + 2 NAD+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "3-nitrophenol nitroreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1497"^^xsd:string) "Catalysis of the reaction: aminohydroquinone + 2 e- + 2 H+ + 1/2 O2 = 1,2,4-benzenetriol + NH3."^^xsd:string) AnnotationAssertion(rdfs:label "aminohydroquinone monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NAD-dependent protein deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the removal of one or more acetyl groups from a protein, requiring NAD."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "iron chaperone activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "Assists in the delivery of iron ions to target proteins or compartments."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "immunoglobulin receptor binding"^^xsd:string) AnnotationAssertion( "Fc receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with one or more specific sites on an immunoglobulin receptor molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Fc-gamma receptor I complex binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with one or more specific sites on the Fc-gamma receptor I complex. The complex functions primarily as an activating receptor for IgG."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:10209156"^^xsd:string) Annotation( "PMID:9255069"^^xsd:string) "Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to phosphatidylinositol or one of its phosphorylated derivatives at the 3' position of the inositol ring."^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "phosphoinositide 3-kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol 3-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phosphatidylinositol 3-kinase activity, class I"^^xsd:string) AnnotationAssertion( "phosphatidylinositol-4-phosphate 3-kinase activity"^^xsd:string) AnnotationAssertion( "phosphatidylinositol 3-kinase activity, class II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.154"^^xsd:string) Annotation( "RHEA:18376"^^xsd:string) "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.154"^^xsd:string) "type II phosphoinositide 3-kinase activity"^^xsd:string) AnnotationAssertion( "phosphatidylinositol 3-kinase, class I, catalyst activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.154"^^xsd:string) "C2-domain-containing phosphoinositide 3-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.154"^^xsd:string) "ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-phosphatidylinositol-4-phosphate 3-kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "myosuppressin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Combining with the peptide myosuppressin to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "phosphoinositide 3-kinase regulator activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol 3-kinase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:9255069"^^xsd:string) "Modulates the activity of any of the phosphatidylinositol 3-kinases (PI3Ks). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates."^^xsd:string) AnnotationAssertion( "PI3K regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "histone deacetylase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Modulates the activity of histone deacetylase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "histone acetylase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Modulates the activity of histone acetyltransferase."^^xsd:string) AnnotationAssertion(rdfs:label "histone acetyltransferase regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "histone acetylase binding"^^xsd:string) AnnotationAssertion(rdfs:label "histone acetyltransferase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Interacting selectively and non-covalently with the enzyme histone acetyltransferase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "juvenile hormone acid methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Catalysis of the transfer of a methyl group to juvenile hormone acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:14585615"^^xsd:string) "Interacting selectively and non-covalently with a methylated residue on a histone protein. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes."^^xsd:string) AnnotationAssertion(rdfs:label "methylated histone residue binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "PMID:11395417"^^xsd:string) "Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "phosphoinositide binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0582227089"^^xsd:string) "Interacting selectively and non-covalently with 20-hydroxyecdysone (ecdysone). Ecdysone is an ecdysteroid produced by the prothoracic glands of immature insects and the ovaries of adult females, which stimulates growth and molting."^^xsd:string) AnnotationAssertion(rdfs:label "ecdysone binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes."^^xsd:string) AnnotationAssertion(rdfs:label "histone kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone serine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Catalysis of the transfer of a phosphate group to a serine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes."^^xsd:string) AnnotationAssertion( "histone-serine kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone kinase activity (H3-S10 specific)"^^xsd:string) AnnotationAssertion( "histone serine kinase activity (H3-S10 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:15041176"^^xsd:string) "Catalysis of the transfer of a phosphate group to the serine-10 residue of the N-terminal tail of histone H3."^^xsd:string) AnnotationAssertion( "histone kinase activity (H3-S3 specific)"^^xsd:string) AnnotationAssertion( "histone-serine kinase activity (H3-S10 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "histone-threonine kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "histone threonine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Catalysis of the transfer of a phosphate group to a threonine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:15066275"^^xsd:string) Annotation( "PMID:15066283"^^xsd:string) "Interacting selectively and non-covalently with a small interfering RNA, a 21-23 nucleotide RNA that is processed from double stranded RNA (dsRNA) by an RNAse enzyme."^^xsd:string) AnnotationAssertion(rdfs:label "siRNA binding"^^xsd:string) AnnotationAssertion( "small interfering RNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "miRNA binding"^^xsd:string) AnnotationAssertion( "microRNA binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15066283"^^xsd:string) "Interacting selectively and non-covalently with a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12954617"^^xsd:string) "Interacting selectively and non-covalently with the catalytic subunit of glutamate-cysteine ligase."^^xsd:string) AnnotationAssertion(rdfs:label "glutamate-cysteine ligase catalytic subunit binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Combining with the neuropeptide proctolin, to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "proctolin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "corazonin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Combining with the neuropeptide corazonin to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dopamine binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:14705965"^^xsd:string) Annotation( "RESID:AA0069"^^xsd:string) "Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue."^^xsd:string) AnnotationAssertion(rdfs:label "protein-arginine omega-N monomethyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:14705965"^^xsd:string) Annotation( "RESID:AA0068"^^xsd:string) Annotation( "RESID:AA0069"^^xsd:string) "Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the same terminal nitrogen (omega nitrogen) residue that was previously methylated, resulting in asymmetrical peptidyl-N(omega),N(omega)-dimethylated arginine residues."^^xsd:string) AnnotationAssertion( "type I PRMT activity"^^xsd:string) AnnotationAssertion( "type I protein arginine methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-arginine omega-N asymmetric methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "type II PRMT activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-arginine omega-N symmetric methyltransferase activity"^^xsd:string) AnnotationAssertion( "type II protein arginine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14705965"^^xsd:string) Annotation( "RESID:AA0067"^^xsd:string) Annotation( "RESID:AA0069"^^xsd:string) "Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peptidyl-arginine C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Catalysis of the transfer of a methyl group to the carbon atom of an arginine residue in a protein."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:15130086"^^xsd:string) "Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming an alpha-1,4 linkage."^^xsd:string) AnnotationAssertion( "alpha-1,4-GalNAc transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-1,4-N-acetylgalactosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "http://www.chem.qmul.ac.uk/iubmb/enzyme/reaction/polysacc/UDPsugar.html"^^xsd:string) "Catalysis of the transfer of a galactose group from UDP-galactose to an acceptor molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "http://www.chem.qmul.ac.uk/iubmb/enzyme/reaction/polysacc/UDPsugar.html"^^xsd:string) "Catalysis of the transfer of a glucosyl group from UDP-glucose to an acceptor molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "http://www.chem.qmul.ac.uk/iubmb/enzyme/reaction/polysacc/UDPsugar.html"^^xsd:string) "Catalysis of the transfer of a xylosyl group from UDP-xylose to an acceptor molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutamate receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Interacting selectively and non-covalently with a glutamate receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with an ionotropic glutamate receptor. Ionotropic glutamate receptors bind glutamate and exert an effect through the regulation of ion channels."^^xsd:string) AnnotationAssertion(rdfs:label "ionotropic glutamate receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "PMID:9069287"^^xsd:string) "Interacting selectively and non-covalently with a G-protein coupled glutamate receptor (a metabotropic glutamate receptor)."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "metabotropic glutamate receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled glutamate receptor binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nuclear hormone receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Interacting selectively and non-covalently with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "steroid hormone receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Interacting selectively and non-covalently with a steroid hormone receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucocorticoid receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Interacting selectively and non-covalently with a glucocorticoid receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phthalate binding"^^xsd:string) AnnotationAssertion(Annotation( "http://umbbd.ahc.umn.edu/pth/pth_map.html"^^xsd:string) "Interacting selectively and non-covalently with a phthalate, any ester or salt of phthalic acid."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "diphenyl phthalate binding"^^xsd:string) AnnotationAssertion(Annotation( "http://www.sigmaaldrich.com"^^xsd:string) "Interacting selectively and non-covalently with diphenyl phthalate, C(20)H(14)O(4)."^^xsd:string) AnnotationAssertion( "DPP binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phthalic acid dibutyl ester binding"^^xsd:string) AnnotationAssertion( "DBP binding"^^xsd:string) AnnotationAssertion(Annotation( "http://www.sigmaaldrich.com"^^xsd:string) "Interacting selectively and non-covalently with dibutyl phthalate, C(16)H(22)O(4)."^^xsd:string) AnnotationAssertion(rdfs:label "dibutyl phthalate binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ethanol binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with ethanol, CH(3)-CH(2)-OH."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.158"^^xsd:string) "Ipk1p"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.158"^^xsd:string) "Gsl1p"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.158"^^xsd:string) "IP5 2-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.158"^^xsd:string) Annotation( "RHEA:20316"^^xsd:string) "Catalysis of the reaction: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.158"^^xsd:string) "inositol 1,3,4,5,6-pentakisphosphate 2-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.158"^^xsd:string) "Ins(1,3,4,5,6)P5 2-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.158"^^xsd:string) "ATP:1D-myo-inositol 1,3,4,5,6-pentakisphosphate 2-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol pentakisphosphate 2-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.158"^^xsd:string) "inositol polyphosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.158"^^xsd:string) "inositol-pentakisphosphate 2-kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "PMID:15350618"^^xsd:string) "Catalysis of the hydroxylation of an ecdysteroid at carbon position 25. Ecdysteroids are a group of polyhydroxylated ketosteroids which initiate post-embryonic development, particularly metamorphosis, in insects and other arthropods."^^xsd:string) AnnotationAssertion(rdfs:label "ecdysteroid 25-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5'-3' exodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198547684"^^xsd:string) "Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a DNA molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "TLR binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19076341"^^xsd:string) "Interacting selectively and non-covalently with a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response."^^xsd:string) AnnotationAssertion(rdfs:label "Toll-like receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) Annotation( "GOC:txnOH"^^xsd:string) Annotation( "SO:0000165"^^xsd:string) "Interacting selectively and non-covalently with an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter."^^xsd:string) AnnotationAssertion(rdfs:label "enhancer binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "SECIS binding"^^xsd:string) AnnotationAssertion(rdfs:label "selenocysteine insertion sequence binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "PMID:10760958"^^xsd:string) "Interacting selectively and non-covalently with the selenocysteine insertion sequence (SECIS), a regulatory sequence within mRNA which directs incorporation of a selenocysteine at a stop codon (UGA) during translation."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chondroitin sulfate proteoglycan binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kmv"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kmv"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc)."^^xsd:string) AnnotationAssertion(rdfs:label "chondroitin sulfate binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "proenzyme binding"^^xsd:string) AnnotationAssertion(rdfs:label "zymogen binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:yaf"^^xsd:string) "Enables the transfer of carbon dioxide (CO2) from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "carbon dioxide transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "very-long-chain-3-hydroxyacyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:27283"^^xsd:string) Annotation( "GOC:pde"^^xsd:string) "Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a very long-chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22."^^xsd:string) AnnotationAssertion(rdfs:label "very long-chain-3-hydroxyacyl-CoA dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ATP-gated ion channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Catalysis of the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Catalysis of the transfer of a phosphate group to a tyrosine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes."^^xsd:string) AnnotationAssertion( "histone-tyrosine kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "histone tyrosine kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "histone tyrosine kinase activity (H3-Y41 specific)"^^xsd:string) AnnotationAssertion( "histone-tyrosine kinase activity (H3-Y41 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone kinase activity (H3-Y41 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "The modification of histone H3 by the addition of a phosphate group to a tyrosine residue at position 41 of the histone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Catalysis of the transfer of a phosphate group to the threonine-11 residue of the N-terminal tail of histone H3."^^xsd:string) AnnotationAssertion( "histone-threonine kinase activity (H3-T11 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone kinase activity (H3-T11 specific)"^^xsd:string) AnnotationAssertion( "histone threonine kinase activity (H3-T11 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "histone-threonine kinase activity (H3-T6 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone kinase activity (H3-T6 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Catalysis of the transfer of a phosphate group to the threonine-6 residue of the N-terminal tail of histone H3."^^xsd:string) AnnotationAssertion( "histone threonine kinase activity (H3-T6 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) Annotation( "PMID:4152755"^^xsd:string) Annotation( "http://www.brenda-enzymes.org/php/result_flat.php4?ecno=1.1.1.63"^^xsd:string) "Catalysis of the reaction: 5alpha-dihydrotestosterone + NAD+ = 5alpha-androstane-3,17-dione + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "dihydrotestosterone 17-beta-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclic-di-GMP binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:49537"^^xsd:string) "3',5'-cyclic di-GMP binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:49537"^^xsd:string) "cyclic dinucleotide di-GMP binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:49537"^^xsd:string) "c-di-GMP binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:49537"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) "Interacting selectively and non-covalently with cyclic-di-GMP, cyclic dimeric guanosine monophosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.5.1.16"^^xsd:string) "halima-5(6),13-dien-15-yl-diphosphate lyase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.16"^^xsd:string) "halimadienyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "halimadienyl-diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.16"^^xsd:string) "Catalysis of the reaction: geranylgeranyl diphosphate = halima-5(6),13-dien-15-yl diphosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.1.13"^^xsd:string) "MshC ligase"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12033919"^^xsd:string) "desacetylmycothiol synthase"^^xsd:string) AnnotationAssertion(rdfs:label "cysteine-glucosaminylinositol ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.13"^^xsd:string) Annotation( "MetaCyc:RXN1G-4"^^xsd:string) Annotation( "PMID:12033919"^^xsd:string) "Catalysis of the reaction: 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + L-cysteine + ATP = 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + 2 H+. 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol is also known as glucosaminyl-inositol or GlcN-Ins, and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as desacetylmycothiol or Cys-GlcN-Ins."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.13"^^xsd:string) "L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mycothiol synthase activity"^^xsd:string) AnnotationAssertion( "acetyl-CoA:Cys-GlcN-Ins acetyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:MONOMER-9684"^^xsd:string) Annotation( "PMID:12033919"^^xsd:string) "Catalysis of the reaction: 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = mycothiol + coenzyme A + H+. Mycothiol is also known as AcCys-GlcN-Ins and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as Cys-GlcN-Ins or desacetylmycothiol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-ascorbate 6-phosphate lactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18097099"^^xsd:string) Annotation( "PMID:20359483"^^xsd:string) "Catalysis of the reaction: L-ascorbate 6-phosphate + H2O = 3-keto-L-gulonate 6-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "choriogonadotropin hormone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "chorio-gonadotrophin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "chorionic gonadotropin hormone receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "PMID:1922095"^^xsd:string) "Combining with the choriogonadotropin hormone to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "CG receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) "Interacting selectively and non-covalently with any lipase."^^xsd:string) AnnotationAssertion(rdfs:label "lipase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "http://www.britannica.com/EBchecked/topic/117461/chylomicron"^^xsd:string) "Interacting selectively and non-covalently with a chylomicron, a large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE."^^xsd:string) AnnotationAssertion(rdfs:label "chylomicron binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jh"^^xsd:string) "A/A mispair binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:jh"^^xsd:string) "Interacting selectively and non-covalently with double-stranded DNA containing an A/A mispair."^^xsd:string) AnnotationAssertion(rdfs:label "adenine/adenine mispair binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "G/A mispair binding"^^xsd:string) AnnotationAssertion(rdfs:label "adenine/guanine mispair binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jh"^^xsd:string) "A/G mispair binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:jh"^^xsd:string) "Interacting selectively and non-covalently with double-stranded DNA containing an A/G mispair."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "guanine-adenine mispair binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jh"^^xsd:string) "C/C mispair binding"^^xsd:string) AnnotationAssertion(rdfs:label "cytosine/cytosine mispair binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:jh"^^xsd:string) "Interacting selectively and non-covalently with double-stranded DNA containing a C/C mispair."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "T/T mispair binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:jh"^^xsd:string) "Interacting selectively and non-covalently with double-stranded DNA containing a T/T mispair."^^xsd:string) AnnotationAssertion(rdfs:label "thymine/thymine mispair binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "thymine/cytosine mispair binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:jh"^^xsd:string) "Interacting selectively and non-covalently with double-stranded DNA containing a C/T mispair."^^xsd:string) AnnotationAssertion(rdfs:label "cytosine/thymine mispair binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "T/C mispair binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jh"^^xsd:string) "C/T mispair binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:jh"^^xsd:string) "Interacting selectively and non-covalently with double-stranded DNA containing a G/G mispair."^^xsd:string) AnnotationAssertion(rdfs:label "guanine/guanine mispair binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jh"^^xsd:string) "G/G mispair binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lipopolysaccharide-1,5-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11304545"^^xsd:string) "LPS-1,5-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11304545"^^xsd:string) "UDP-D-galactose:(glucosyl)lipopolysaccharide-1,5-D-galactosyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.-"^^xsd:string) Annotation( "PMID:11304545"^^xsd:string) "Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,5 alpha-D-galactosyl-lipopolysaccharide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:2900470"^^xsd:string) "cyclic-AMP response element binding"^^xsd:string) AnnotationAssertion(rdfs:label "cAMP response element binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:2875459"^^xsd:string) "cAMP-responsive element binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:2900470"^^xsd:string) "cyclic AMP response element binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:2875459"^^xsd:string) Annotation( "PMID:2900470"^^xsd:string) "Interacting selectively and non-covalently with the cyclic AMP response element (CRE), a short palindrome-containing sequence found in the promoters of genes whose expression is regulated in response to cyclic AMP."^^xsd:string) AnnotationAssertion(Annotation( "PMID:2875459"^^xsd:string) "cyclic-AMP-responsive element binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:2900470"^^xsd:string) "CRE binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "Pfam:PF03166"^^xsd:string) "MAD homology 2 domain binding"^^xsd:string) AnnotationAssertion(rdfs:label "MH2 domain binding"^^xsd:string) AnnotationAssertion(Annotation( "Pfam:PF03166"^^xsd:string) "Interacting selectively and non-covalently with the MH2 (MAD homology 2) domain of a protein. The MH2 domain is found at the carboxy terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "MH1 domain binding"^^xsd:string) AnnotationAssertion(Annotation( "Pfam:PF03165"^^xsd:string) "Interacting selectively and non-covalently with the MH1 (MAD homology 1) domain of a protein. The MH1 domain is found at the amino terminus of MAD related proteins such as Smads and can mediate DNA binding in some proteins. Smads also use the MH1 domain to interact with some transcription factors."^^xsd:string) AnnotationAssertion(Annotation( "Pfam:PF03165"^^xsd:string) "MAD homology 1 domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Catalysis of the removal of a methyl group from one or more nucleosides within a DNA molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12594517"^^xsd:string) Annotation( "PMID:16482161"^^xsd:string) Annotation( "PMID:18775698"^^xsd:string) "Catalysis of the removal of a methyl group from one or more nucleosides within a RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms."^^xsd:string) AnnotationAssertion(rdfs:label "oxidative RNA demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17991826"^^xsd:string) "2-oxoglutarate-dependent RNA demethylase"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidative DNA demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12594517"^^xsd:string) Annotation( "PMID:16482161"^^xsd:string) Annotation( "PMID:18775698"^^xsd:string) "Catalysis of the removal of the methyl group from one or more nucleotides within a DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms."^^xsd:string) AnnotationAssertion(Annotation( "PMID:17991826"^^xsd:string) "2-oxoglutarate-dependent DNA demethylase"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-hydroxypropionate dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:26441"^^xsd:string) "Catalysis of the reaction: 3-hydroxypropanoate + NADP+ = 3-oxopropanoate + H+ + NADPH."^^xsd:string) AnnotationAssertion( "3-hydroxypropanoate dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.298"^^xsd:string) "3-hydroxypropanoate:NADP+ oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.298"^^xsd:string) "3-hydroxypropionate:NADP+ oxidoreductase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NADH pyrophosphatase activity"^^xsd:string) AnnotationAssertion( "NADH diphosphatase activity"^^xsd:string) AnnotationAssertion( "NADH pyrophosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-4401"^^xsd:string) Annotation( "PMID:12399474"^^xsd:string) Annotation( "PMID:20181750"^^xsd:string) "Catalysis of the reaction: NADH + H2O = AMP + NMNH + 2 H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:20001964"^^xsd:string) "ChoRE binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "PMID:20001964"^^xsd:string) "Interacting selectively and non-covalently with the carbohydrate response element (ChoRE) found in the promoters of genes whose expression is regulated in response to carbohydrates, such as the triglyceride synthesis genes."^^xsd:string) AnnotationAssertion(rdfs:label "carbohydrate response element binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:17804481"^^xsd:string) "8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17804481"^^xsd:string) Annotation( "PMID:7782328"^^xsd:string) Annotation( "PMID:7859359"^^xsd:string) "Catalysis of the reaction: 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate + H2O = 8-oxo-7,8-dihydrodeoxyguanosine phosphate + diphosphate. 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate, or 8-oxo-dGTP, is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for DNA synthesis causing transversion mutations. 8-oxo-dGTPase hydrolyses 8-oxo-dGTP to its monophosphate form to prevent the misincorporation of 8-oxo-dGTP into cellular DNA."^^xsd:string) AnnotationAssertion(Annotation( "PMID:7782328"^^xsd:string) "8-oxo-7,8-dihydrodeoxyguanosine triphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17804481"^^xsd:string) "8-oxo-7,8-dihydro-deoxyguanosine triphosphate pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17804481"^^xsd:string) "8-oxo-dGTP pyrophosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:7782328"^^xsd:string) "8-oxo-dGTPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.82"^^xsd:string) "PPD activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.82"^^xsd:string) "phedase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.82"^^xsd:string) Annotation( "PMID:16228561"^^xsd:string) "Catalysis of the reaction: pheophorbide a + H2O = pyropheophorbide a + methanol + CO2. The reaction occurs in two steps; pheophoridase catalyzes the conversion of pheophorbide a to a precursor of pyropheophorbide a, C-13(2)-carboxylpyropheophorbide a, by demethylation, and then the precursor is decarboxylated non-enzymatically to yield pyropheophorbide a."^^xsd:string) AnnotationAssertion(rdfs:label "pheophoridase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone demethylase activity (H4-K20 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.27"^^xsd:string) Annotation( "PMID:20622853"^^xsd:string) "Catalysis of the reaction: histone H4 N6-methyl-L-lysine (position 20) + 2-oxoglutarate + O2 = histone H4 L-lysine (position 20) + succinate + formaldehyde + CO2. This reaction is the removal of a methyl group from lysine at position 20 of the histone H4 protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "purinergic receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9755289"^^xsd:string) "purinoceptor"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9755289"^^xsd:string) "purinoreceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:9755289"^^xsd:string) "Combining with a purine or purine derivative (purine nucleoside or purine nucleotide) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "signalling adaptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "signaling adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ganglioside binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:yaf"^^xsd:string) "Interacting selectively and non-covalently with a ganglioside, a ceramide oligosaccharide carrying in addition to other sugar residues, one or more sialic acid residues."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-acetylglucosaminylinositol deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.103"^^xsd:string) "N-acetyl-1D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.103"^^xsd:string) "1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.103"^^xsd:string) "1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rs"^^xsd:string) "GlcNAc-Ins deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.103"^^xsd:string) Annotation( "GOC:rs"^^xsd:string) "Catalysis of the reaction: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate. This reaction is the hydrolysis of an acetyl group from N-acetylglucosaminylinositol."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jh2"^^xsd:string) Annotation( "PMID:20472640"^^xsd:string) "Catalysis of the addition of a methylthioether group (-SCH3) to a nucleic acid or protein acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "methylthiotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:20472640"^^xsd:string) "MTTase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:20472640"^^xsd:string) "Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-isopentenyladenosine (i6A) in tRNA, to form 2-methylthio-N6-isopentenyladenosine (ms2i6A)."^^xsd:string) AnnotationAssertion(Annotation( "PMID:20472640"^^xsd:string) "i6A methylthiotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N6-isopentenyladenosine methylthiotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:20472640"^^xsd:string) "t6A methylthiotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:20472640"^^xsd:string) Annotation( "PMID:20584901"^^xsd:string) "Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-threonylcarbomyladenosine (t6A) in tRNA, to form 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A)."^^xsd:string) AnnotationAssertion(rdfs:label "N6-threonylcarbomyladenosine methylthiotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aspartic acid methylthiotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18252828"^^xsd:string) Annotation( "PMID:8844851"^^xsd:string) Annotation( "RESID:AA0232"^^xsd:string) "Catalysis of the methylthiolation (-SCH3 addition) of the beta-carbon of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peptidyl-cysteine S-nitrosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) "protein nitrosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:20972426"^^xsd:string) "S-nitrosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.99.-"^^xsd:string) Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:20972425"^^xsd:string) Annotation( "PMID:20972426"^^xsd:string) "Catalysis of the transfer of a nitric oxide (NO) group to a sulphur atom within a cysteine residue of a protein."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "PMID:12221107"^^xsd:string) Annotation( "PMID:15728179"^^xsd:string) Annotation( "PMID:21097499"^^xsd:string) "Interacting selectively and non-covalently with the AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC)."^^xsd:string) AnnotationAssertion(rdfs:label "AP-2 adaptor complex binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "AP-2 clathrin adaptor complex binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA stem-loop binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:16568238"^^xsd:string) Annotation( "PMID:20455544"^^xsd:string) "Interacting selectively and non-covalently with a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop."^^xsd:string) AnnotationAssertion(Annotation( "PMID:16568238"^^xsd:string) "RNA hairpin binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16568238"^^xsd:string) "RNA hairpin loop binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16568238"^^xsd:string) "snRNA hairpin binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16568238"^^xsd:string) "snRNA hairpin loop binding"^^xsd:string) AnnotationAssertion(rdfs:label "snRNA stem-loop binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:16568238"^^xsd:string) Annotation( "PMID:20455544"^^xsd:string) "Interacting selectively and non-covalently with a stem-loop in a small nuclear RNA (snRNA). An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop."^^xsd:string) AnnotationAssertion( "small nuclear RNA stem-loop binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "PMID:15728179"^^xsd:string) "The binding activity of a molecule that brings together clathrin and one or more other molecules, permitting them to function in a coordinated way."^^xsd:string) AnnotationAssertion(rdfs:label "clathrin adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15728179"^^xsd:string) "clathrin-associated adaptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "ceramide transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:14685229"^^xsd:string) "Enables the directed movement of ceramides into, out of or within a cell, or between cells. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "purine ribonucleoside triphosphate binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:26398"^^xsd:string) Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:ebc"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar."^^xsd:string) AnnotationAssertion(Annotation( "GOC:ebc"^^xsd:string) "purine NTP binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "histone-arginine N-methyltransferase activity (H3-R17 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "histone methylase activity (H3-R17 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone methyltransferase activity (H3-R17 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:11341840"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 17) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 17). This reaction is the addition of a methyl group to arginine at position 17 of histone H3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:15765"^^xsd:string) "L-dopa receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15765"^^xsd:string) Annotation( "PMID:18828673"^^xsd:string) Annotation( "Wikipedia:L-DOPA"^^xsd:string) "Combining with L-DOPA to initiate a change in cell activity. L-DOPA is the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl) propanoic acid, and is the precursor to dopamine, norepinephrine (noradrenaline) and epinephrine."^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15765"^^xsd:string) "L-beta-(3,4-Dihydroxyphenyl)alanine receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-DOPA receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) Annotation( "MetaCyc:RXN-9726"^^xsd:string) Annotation( "PMID:19166903"^^xsd:string) "Catalysis of the reaction: a 3-oxo-delta-4,5-steroid + NADPH + H(+) = a 5-beta-3-oxo-steroid + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) "3-oxo-delta4,5-steroid 5beta-reductase"^^xsd:string) AnnotationAssertion(rdfs:label "3-oxo-delta(4,5)-steroid 5-beta-reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:21097499"^^xsd:string) "Interacting selectively and non-covalently with the AP-1 adaptor complex. The AP-1 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C)."^^xsd:string) AnnotationAssertion(rdfs:label "AP-1 adaptor complex binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "AP-3 adaptor complex binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:21097499"^^xsd:string) "Interacting selectively and non-covalently with the AP-3 adaptor complex. The AP-3 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "kinesin-melanosome adaptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "kinesin-associated melanosomal adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19841138"^^xsd:string) "The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to melanosomes."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "TLR4 binding"^^xsd:string) AnnotationAssertion(rdfs:label "Toll-like receptor 4 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "PMID:18304834"^^xsd:string) "Interacting selectively and non-covalently with a Toll-like 4 protein, a pattern recognition receptor that binds bacterial lipopolysaccharide (LPS) to initiate an innate immune response."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Toll-like receptor 2 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "TLR2 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) "Interacting selectively and non-covalently with a Toll-like 2 protein, a pattern recognition receptor that binds microbial pattern motifs to initiate an innate immune response."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) Annotation( "PMID:17945329"^^xsd:string) Annotation( "PMID:19166903"^^xsd:string) "Catalysis of the reaction: an enone + NADPH + H+ = a ketone + NADP+."^^xsd:string) AnnotationAssertion(rdfs:label "enone reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) "Catalysis of the transfer of oligopeptides from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "oligopeptide transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) "Interacting selectively and non-covalently with chemokine (C-C motif) ligand 2."^^xsd:string) AnnotationAssertion(Annotation( "GOC:ebc"^^xsd:string) "CCL2 binding"^^xsd:string) AnnotationAssertion(rdfs:label "chemokine (C-C motif) ligand 2 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) "Interacting selectively and non-covalently with chemokine (C-C motif) ligand 12."^^xsd:string) AnnotationAssertion(Annotation( "GOC:ebc"^^xsd:string) "CCL12 binding"^^xsd:string) AnnotationAssertion(rdfs:label "chemokine (C-C motif) ligand 12 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ebc"^^xsd:string) "CCL7 binding"^^xsd:string) AnnotationAssertion(rdfs:label "chemokine (C-C motif) ligand 7 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) "Interacting selectively and non-covalently with chemokine (C-C motif) ligand 7."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19601712"^^xsd:string) "MIF binding"^^xsd:string) AnnotationAssertion(rdfs:label "macrophage migration inhibitory factor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "PMID:19601712"^^xsd:string) "Interacting selectively and non-covalently with the cytokine, macrophage migration inhibitory factor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lysophosphatidic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:52288"^^xsd:string) "Interacting selectively and non-covalently with lysophosphatidic acid (LPA), a phospholipid derivative that acts as a potent mitogen due to its activation of high-affinity G-protein-coupled receptors."^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:52288"^^xsd:string) "LPA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:50091"^^xsd:string) Annotation( "GOC:BHF"^^xsd:string) "Interacting selectively and non-covalently with S-nitrosoglutathione, a nitrosothiol considered to be a natural nitric oxide (NO) donor involved in S-nitrosylation, and in the storage and transport of nitric oxide in biological systems."^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:50091"^^xsd:string) "GSNO binding"^^xsd:string) AnnotationAssertion(rdfs:label "S-nitrosoglutathione binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10534443"^^xsd:string) "DNIC binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12871931"^^xsd:string) "dinitrosyl-diglutathionyl-iron complex binding"^^xsd:string) AnnotationAssertion(rdfs:label "dinitrosyl-iron complex binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "PMID:10534443"^^xsd:string) "Interacting selectively and non-covalently with a dinitrosyl-iron complex. Nitric oxide (NO) is stored as dinitrosyl-iron complexes, which form spontaneously from Glutathione (GSH), S-nitrosoglutathione, and trace amounts of ferrous ions, or by reaction of iron-sulfur centers with NO."^^xsd:string) AnnotationAssertion(Annotation( "PMID:12871931"^^xsd:string) "DNDGIC binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:28494"^^xsd:string) Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:17028579"^^xsd:string) Annotation( "PMID:21397848"^^xsd:string) "Catalysis of the hydrolysis of cardiolipin (1,3-bis(3-phosphatidyl)glycerol) to form phosphatidic acid (PA)."^^xsd:string) AnnotationAssertion(rdfs:label "cardiolipin hydrolase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) "Interacting selectively and non-covalently with chemokine (C-C motif) ligand 19."^^xsd:string) AnnotationAssertion(rdfs:label "chemokine (C-C motif) ligand 19 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "CCL19 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chemokine (C-C motif) ligand 21 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "CCL21 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) "Interacting selectively and non-covalently with chemokine (C-C motif) ligand 21."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:30477"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:kad"^^xsd:string) Annotation( "PMID:11053398"^^xsd:string) Annotation( "PMID:21244361"^^xsd:string) "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to tellurite [TeO3(2-)]. Methylated derivatives of tellurite include Te(CH3)2 (dimethyltelluride) and Te2(CH3)2 (dimethylditelluride)."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "tellurite methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "SAM-dependent tellurite methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tellurite methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "S-adenosyl-L-methionine-dependent tellurite methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:kad"^^xsd:string) "NADPH:2-alkenal alpha,beta-hydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-alkenal reductase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:kad"^^xsd:string) Annotation( "PMID:16299173"^^xsd:string) "Catalysis of the reaction: n-alkanal + NADP+ = alk-2-enal + NADPH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "deubiquitinase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) Annotation( "ISBN:0120793709"^^xsd:string) "Increases the activity of deubiquitinase, an enzyme that catalyzes the hydrolysis of various forms of polymeric ubiquitin sequences."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16944418"^^xsd:string) Annotation( "PMID:17163408"^^xsd:string) "structural constituent of vitelline envelope"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16944418"^^xsd:string) Annotation( "PMID:17163408"^^xsd:string) "The action of a molecule that contributes to the structural integrity of an egg coat. An egg coat is a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development."^^xsd:string) AnnotationAssertion(Annotation( "PMID:16944418"^^xsd:string) Annotation( "PMID:17163408"^^xsd:string) "structural constituent of zona pellucida"^^xsd:string) AnnotationAssertion(rdfs:label "structural constituent of egg coat"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "rubidium ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:49847"^^xsd:string) "rubidium cation transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "rubidium transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:49847"^^xsd:string) "Rb+ transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:49847"^^xsd:string) Annotation( "GOC:yaf"^^xsd:string) "Catalysis of the transfer of rubidium ions (Rb+) from one side of a membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "InterPro:IPR001909"^^xsd:string) "Interacting selectively and non-covalently with a Krueppel-associated box (KRAB) domain of a protein. The approximately 75 amino acid KRAB domain is enriched in charged amino acids, and is found in the N-terminal regions of many zinc finger-containing transcription factors."^^xsd:string) AnnotationAssertion(rdfs:label "Krueppel-associated box domain binding"^^xsd:string) AnnotationAssertion(Annotation( "InterPro:IPR001909"^^xsd:string) "KRAB domain binding"^^xsd:string) AnnotationAssertion(Annotation( "InterPro:IPR001909"^^xsd:string) "Krueppel-associated box binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "KEGG:R03531"^^xsd:string) "2'-Deoxyinosine-5'-triphosphate pyrophosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "dITP pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "deoxyinosine triphosphate pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.-"^^xsd:string) Annotation( "GOC:dgf"^^xsd:string) Annotation( "PMID:21548881"^^xsd:string) Annotation( "RHEA:28342"^^xsd:string) "Catalysis of the reaction: dITP + H2O = dIMP + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "dITP diphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "InterPro:IPR001875"^^xsd:string) "DED binding"^^xsd:string) AnnotationAssertion(rdfs:label "death effector domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) Annotation( "InterPro:IPR001875"^^xsd:string) "Interacting selectively and non-covalently with a DED domain (death effector domain) of a protein, a homotypic protein interaction module composed of a bundle of six alpha-helices that is related in structure to the death domain (DD)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "exochitinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.-"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:kah"^^xsd:string) Annotation( "GOC:pde"^^xsd:string) Annotation( "PMID:11468293"^^xsd:string) Annotation( "PMID:16298970"^^xsd:string) Annotation( "PMID:21390509"^^xsd:string) "Catalysis of the hydrolysis of terminal 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, exochitinases progressively cleave off two subunits from the reducing or non-reducing ends of the chitin chain."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "isoguanine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14709079"^^xsd:string) "2-oxoadenine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.-"^^xsd:string) Annotation( "GOC:imk"^^xsd:string) Annotation( "PMID:21604715"^^xsd:string) "Catalysis of the reaction: isoguanine + H2O = xanthine + NH3."^^xsd:string) AnnotationAssertion(Annotation( "PMID:14709079"^^xsd:string) Annotation( "PMID:8841637"^^xsd:string) "2-hydroxyadenine deaminase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:5130"^^xsd:string) "2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid binding"^^xsd:string) AnnotationAssertion(rdfs:label "flurbiprofen binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:5130"^^xsd:string) Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Interacting selectively and non-covalently with flurbiprofen."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:8578590"^^xsd:string) "mRNA 3'-UTR adenylate/uridylate-rich element binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "mRNA 3'-UTR AU-rich region binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "microsatellite binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:21290414"^^xsd:string) "variable number tandem repeat binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:yaf"^^xsd:string) Annotation( "PMID:21290414"^^xsd:string) Annotation( "SO:0000289"^^xsd:string) "Interacting selectively and non-covalently with a microsatellite, a repeat_region in DNA containing repeat units (2 to 4 base pairs) that is repeated multiple times in tandem."^^xsd:string) AnnotationAssertion(Annotation( "SO:0000289"^^xsd:string) "VNTR binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "microsatellite DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:yaf"^^xsd:string) Annotation( "PMID:16061642"^^xsd:string) "Catalysis of the transfer of a phosphate group to the serine-139 residue of the C-terminal tail of histone H2A."^^xsd:string) AnnotationAssertion(rdfs:label "histone kinase activity (H2A-S139 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:16061642"^^xsd:string) "histone kinase activity (H2A.x-S139 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nitric oxide sensor activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:16480"^^xsd:string) "NO sensor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kmv"^^xsd:string) Annotation( "PMID:21491957"^^xsd:string) "Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of nitric oxide (NO)."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:kmv"^^xsd:string) Annotation( "PMID:21901112"^^xsd:string) Annotation( "SO:0000120"^^xsd:string) "Interacting selectively and non-covalently with pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "pre-mRNA binding"^^xsd:string) AnnotationAssertion(Annotation( "SO:0000120"^^xsd:string) "protein-coding primary transcript binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:yaf"^^xsd:string) Annotation( "InterPro:IPR003018"^^xsd:string) "Interacting selectively and non-covalently with the GAF domain of a protein."^^xsd:string) AnnotationAssertion(rdfs:label "GAF domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "PMID:11847124"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamine = S-adenosyl-L-homocysteine + protein N-methyl-L-glutamine."^^xsd:string) AnnotationAssertion(rdfs:label "protein-glutamine N-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mediator complex binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:yaf"^^xsd:string) Annotation( "PMID:18391015"^^xsd:string) "Interacting selectively and non-covalently with a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "long-chain fatty acid binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12641450"^^xsd:string) "long chain fatty acid binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15904"^^xsd:string) Annotation( "GOC:pm"^^xsd:string) Annotation( "PMID:12641450"^^xsd:string) "Interacting selectively and non-covalently with a long-chain fatty acid. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:33184"^^xsd:string) Annotation( "GOC:pm"^^xsd:string) "Interacting selectively and non-covalently with a long-chain fatty acyl-CoA. A long-chain fatty acyl-CoA is any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more."^^xsd:string) AnnotationAssertion(rdfs:label "long-chain fatty acyl-CoA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "protein malonyl lysine demalonylation activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:21908771"^^xsd:string) Annotation( "PMID:22076378"^^xsd:string) "Catalysis of the reaction: protein-malonyllysine + H2O => protein-lysine + malonate. This reaction is the removal of a malonyl group (CO-CH2-CO) from a malonylated lysine residue of a protein or peptide."^^xsd:string) AnnotationAssertion(rdfs:label "protein-malonyllysine demalonylase activity"^^xsd:string) AnnotationAssertion( "peptidyl-malonyllysine demalonylase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:21908771"^^xsd:string) "protein lysine demalonylation activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:22076378"^^xsd:string) "Catalysis of the reaction: protein-succinyllysine + H2O => protein-lysine + succinate. This reaction is the removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue of a protein or peptide."^^xsd:string) AnnotationAssertion( "succinyllysine desuccinylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "succinyl lysine desuccinylase activity"^^xsd:string) AnnotationAssertion( "peptidyl-succinyllysine desuccinylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-succinyllysine desuccinylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "purine nucleotide-sugar transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:19948734"^^xsd:string) "Catalysis of the transfer of a purine nucleotide-sugar from one side of the membrane to the other. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:19135896"^^xsd:string) "Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular ammonia (NH3) has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion(Annotation( "PMID:19135896"^^xsd:string) "ionotropic ammonia receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "extracellular ammonia-gated ion channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:19135896"^^xsd:string) "Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular phenylacetaldehyde has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion(rdfs:label "extracellular phenylacetaldehyde-gated ion channel activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19135896"^^xsd:string) "ionotropic phenylacetaldehyde receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) Annotation( "GOC:pde"^^xsd:string) Annotation( "GOC:pm"^^xsd:string) "Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeric, non-encoded molecule."^^xsd:string) AnnotationAssertion(rdfs:label "small molecule binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:14709540"^^xsd:string) "PEX19-dependent mPTS binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pm"^^xsd:string) Annotation( "PMID:14709540"^^xsd:string) Annotation( "PMID:17020786"^^xsd:string) "Interacting selectively and non-covalently with a class I peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-dependent manner."^^xsd:string) AnnotationAssertion(Annotation( "PMID:14709540"^^xsd:string) "class 1 mPTS binding"^^xsd:string) AnnotationAssertion(rdfs:label "peroxisome membrane class-1 targeting sequence binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peroxisome membrane class-2 targeting sequence binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14709540"^^xsd:string) "class 2 mPTS binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pm"^^xsd:string) Annotation( "PMID:14709540"^^xsd:string) Annotation( "PMID:17020786"^^xsd:string) "Interacting selectively and non-covalently with a class II peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-independent manner."^^xsd:string) AnnotationAssertion(Annotation( "PMID:14709540"^^xsd:string) "PEX19-independent mPTS binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kmv"^^xsd:string) "dsDNA-dependent ATP-dependent DNA helicase activity"^^xsd:string) AnnotationAssertion(rdfs:label "double-stranded DNA-dependent ATP-dependent DNA helicase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kmv"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of double-stranded DNA; drives the unwinding of a DNA helix."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "PMID:9660951"^^xsd:string) Annotation( "PR:000000034"^^xsd:string) "Interacting selectively and non-covalently with a member of the bone morphogenetic protein (BMP) family."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "bone morphogenetic protein binding"^^xsd:string) AnnotationAssertion(rdfs:label "BMP binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-sulfino-L-alanine binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:61085"^^xsd:string) Annotation( "GOC:al"^^xsd:string) "cysteine sulfinate binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:61085"^^xsd:string) Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:8346915"^^xsd:string) "Interacting selectively and non-covalently with 3-sulfino-L-alanine (cysteine sulfinate)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mw"^^xsd:string) Annotation( "KEGG:R02264"^^xsd:string) Annotation( "PMID:10622721"^^xsd:string) Annotation( "PMID:14979715"^^xsd:string) Annotation( "PMID:16475787"^^xsd:string) "Catalysis of the reaction: prostaglandin H2 + NADPH + H+ -> prostaglandin F2alpha + NADP+. This reaction is the reduction of prostaglandin H2 ((5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate) to prostaglandin F2alpha ((5Z,13E)-(15S)-9alpha,11alpha,15-Trihydroxyprosta-5,13-dienoate)."^^xsd:string) AnnotationAssertion(rdfs:label "prostaglandin H2 endoperoxidase reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12664595"^^xsd:string) "PGH2 9,11-endoperoxidase"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12432932"^^xsd:string) "PGH2 9-,11-endoperoxide reductase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) Annotation( "GOC:mw"^^xsd:string) Annotation( "KEGG:R02799"^^xsd:string) Annotation( "PMID:1504718"^^xsd:string) Annotation( "PMID:3862115"^^xsd:string) "Catalysis of the reaction: prostaglandin D2 + H+ + NADPH -> 11-epi-prostaglandin F2alpha + NADP+."^^xsd:string) AnnotationAssertion(rdfs:label "prostaglandin D2 11-ketoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14996743"^^xsd:string) "PGD2 11-ketoreductase"^^xsd:string) AnnotationAssertion(Annotation( "PMID:7248318"^^xsd:string) "prostaglandin 11-keto reductase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.48"^^xsd:string) "15-oxo-delta13-prostaglandin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.48"^^xsd:string) "delta13-15-ketoprostaglandin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.48"^^xsd:string) "prostaglandin 13-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.48"^^xsd:string) "15-ketoprostaglandin delta13-reductase activity"^^xsd:string) AnnotationAssertion( "15-oxoprostaglandin 13-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.48"^^xsd:string) Annotation( "GOC:mw"^^xsd:string) Annotation( "KEGG:R04556"^^xsd:string) Annotation( "KEGG:R04557"^^xsd:string) Annotation( "PMID:17449869"^^xsd:string) "Catalysis of the reaction: 15-keto-prostaglandin + NAD(P)H + H+ -> 13,14-dihydro-15-keto-prostaglandin + NAD(P)+. This reaction is the reduction of 15-keto-prostaglandin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.48"^^xsd:string) "prostaglandin delta13-reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "13-prostaglandin reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:1632314"^^xsd:string) "NAD dependent 11-hydroxythromboxane B2 dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "11-hydroxythromboxane B2 dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mw"^^xsd:string) Annotation( "KEGG:R05060"^^xsd:string) Annotation( "PMID:3461463"^^xsd:string) Annotation( "PMID:3823488"^^xsd:string) Annotation( "PMID:8200461"^^xsd:string) "Catalysis of the reaction: thromboxane B2 + NAD+ = 11-dehydro-thromboxane B2 + NADH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mw"^^xsd:string) "prostaglandin H2 degradation activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mw"^^xsd:string) Annotation( "PMID:11297515"^^xsd:string) "Catalysis of the reaction: prostaglandin H2 = 12-hydroxyheptadecatrienoic acid (HHT) + malonaldehyde (MDA)."^^xsd:string) AnnotationAssertion(rdfs:label "12-hydroxyheptadecatrienoic acid synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "kynurenine-oxaloacetate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "L-kynurenine-oxaloacetate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.-"^^xsd:string) Annotation( "GOC:pde"^^xsd:string) Annotation( "PMID:15606768"^^xsd:string) Annotation( "PMID:4149765"^^xsd:string) "Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-aspartate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "L-kynurenine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "kynurenine-oxo-acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.-"^^xsd:string) Annotation( "GOC:pde"^^xsd:string) "Catalysis of the transfer of an amino group from kynurenine to an acceptor, usually a 2-oxo acid."^^xsd:string) AnnotationAssertion(rdfs:label "kynurenine aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peptidyl-histidine dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:reh"^^xsd:string) Annotation( "PMID:21251231"^^xsd:string) "Catalysis of the reaction: peptidyl L-histidine + 2-oxoglutarate + O2 = peptidyl hydroxy-L-histidine + succinate + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peptidyl-asparagine 3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:reh"^^xsd:string) Annotation( "PMID:12215170"^^xsd:string) "Catalysis of the reaction: peptidyl L-asparagine + 2-oxoglutarate + O2 = peptidyl 3-hydroxy-L-asparagine + succinate + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "L-phenylalanine:oxaloacetate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pde"^^xsd:string) Annotation( "PMID:15606768"^^xsd:string) "Catalysis of the reaction L-phenylalanine + oxaloacetate = phenylpyruvate + aspartate."^^xsd:string) AnnotationAssertion(rdfs:label "L-phenylalanine-oxaloacetate transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:yaf"^^xsd:string) Annotation( "InterPro:IPR000001"^^xsd:string) Annotation( "Wikipedia:Kringle_domain"^^xsd:string) "Interacting selectively and non-covalently with a kringle domain. Kringle domains are protein domains that fold into large loops stabilized by 3 disulfide linkages, and are important in protein-protein interactions with blood coagulation factors."^^xsd:string) AnnotationAssertion(rdfs:label "kringle domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mw"^^xsd:string) Annotation( "KEGG:R06866"^^xsd:string) Annotation( "PMID:620805"^^xsd:string) Annotation( "PMID:7028108"^^xsd:string) "Catalysis of the reaction: 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid -> 2-hexaprenyl-6-methoxyphenol + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mw"^^xsd:string) Annotation( "PMID:620805"^^xsd:string) Annotation( "PMID:7028108"^^xsd:string) "Catalysis of the reaction: 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid -> 2-methoxy-6-decaprenylphenol + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "3-methoxy-4-hydroxy-5-decaprenylbenzoic acid decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thiosulfate binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:16094"^^xsd:string) Annotation( "GOC:db"^^xsd:string) Annotation( "PMID:2188959"^^xsd:string) "Interacting selectively and non-covalently with the inorganic anion thiosulfate, a sulfur oxide that has formula O3S2."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dh"^^xsd:string) Annotation( "PMID:17526838"^^xsd:string) Annotation( "PMID:19383682"^^xsd:string) "Catalysis of the reaction: butane + O2 + NAD(P)H + H+ = butanol + NAD(P)+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "PMID:19383682"^^xsd:string) "sBMO"^^xsd:string) AnnotationAssertion(rdfs:label "butane monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19383682"^^xsd:string) "soluble butane monooxygenase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.17.4.1"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:pde"^^xsd:string) Annotation( "PMID:7476363"^^xsd:string) "Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + glutaredoxin disulfide + H2O -> ribonucleoside diphosphate + glutaredoxin."^^xsd:string) AnnotationAssertion(rdfs:label "ribonucleoside-diphosphate reductase, glutaredoxin disulfide as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "13-lipoxin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mw"^^xsd:string) Annotation( "PMID:10837478"^^xsd:string) "Definition: Catalysis of the reaction: 15-oxolipoxin A4 + NAD(P)H + H+ = 13,14-dihydro-15-oxolipoxin A4 + NAD(P)+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.74"^^xsd:string) "Catalysis of the reaction: abieta-7,13-diene-18-al + H2O + NAD+ = abieta-7,13-diene-18-oate + NADH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "abieta-7,13-dien-18-al dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.74"^^xsd:string) "abietadienal dehydrogenase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "abieta-7,13-diene hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.108"^^xsd:string) "abietadiene hydroxylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.108"^^xsd:string) "Catalysis of the reaction: abieta-7,13-diene + NADPH + H+ + O2 = abieta-7,13-dien-18-ol + NADP+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "indole-2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.137"^^xsd:string) "Catalysis of the reaction: indole + NAD(P)H + H+ + O2 = indolin-2-one + NAD(P)+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "indolin-2-one monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.138"^^xsd:string) "indolin-2-one,NAD(P)H:oxygen oxidoreductase (3-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.138"^^xsd:string) "Catalysis of the reaction: indolin-2-one + NAD(P)H + H+ + O2 = 3-hydroxyindolin-2-one + NAD(P)+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-hydroxyindolin-2-one monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.139"^^xsd:string) "3-hydroxyindolin-2-one,NAD(P)H:oxygen oxidoreductase (2-hydroxy-2H-1,4-benzoxazin-3(4H)-one-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.139"^^xsd:string) "Catalysis of the reaction: 3-hydroxyindolin-2-one + NAD(P)H + H+ + O2 = 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.140"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)H + H+ + O2 = 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxy-1,4-benzoxazin-3-one monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cholest-4-en-3-one 26-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.141"^^xsd:string) "Catalysis of the reaction: cholest-4-en-3-one + NADH + H+ + O2 = 26-hydroxycholest-4-en-3-one + NAD+ + H2O. This reaction involves the hydroxylation of the C26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.142"^^xsd:string) "3-ketosteroid 9alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.142"^^xsd:string) "Catalysis of the reaction: androsta-1,4-diene-3,17-dione + NADH + H+ + O2 = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + NAD+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.142"^^xsd:string) "KshAB activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-ketosteroid 9-alpha-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ent-isokaurene C2-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.143"^^xsd:string) "Catalysis of the reaction: ent-isokaurene + O2 + NADPH + H+ = ent-2alpha-hydroxyisokaurene + H2O + NADP+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.145"^^xsd:string) "ent-cassadiene C11alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.145"^^xsd:string) "Catalysis of the reaction: ent-cassa-12,15-diene + O2 + NADPH + H+ = ent-11beta-hydroxycassa-12,15-diene + NADP+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "ent-cassa-12,15-diene 11-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.146"^^xsd:string) "Catalysis of the reaction: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + O2 + NADPH + H+ = 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "taxoid 14-beta-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.109"^^xsd:string) "Catalysis of the reaction: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18-al + NADP+ + 2 H2O. This is a two step reaction. The first step is: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18,18-diol + + NADP+ + H2O. The second step is a spontaneous reaction: abieta-7,13-dien-18,18-diol = abieta-7,13-dien-18-al + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "abieta-7,13-dien-18-ol hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "9beta-pimara-7,15-diene oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.144"^^xsd:string) "Catalysis of the reaction: 9beta-pimara-7,15-diene + 3 O2 + 3 NADPH + 3 H+ = 9beta-pimara-7,15-dien-19-oate + 3 NADP+ + 4 H2O. This is a three-step reaction: (a) 9beta-pimara-7,15-diene + O2 + NADPH + H+ = 9beta-pimara-7,15-dien-19-ol + NADP+ + H2O, (b) 9beta-pimara-7,15-dien-19-ol + O2 + NADPH + H+ = 9neta-pimara-7,15-dien-19-al + NADP+ + 2 H2O, (c) 9beta-pimara-7,15-dien-19-al + O2 + NADPH + H+ = 9beta-pimara-7,15-dien-19-oate + NADP+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dGTP diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R01855"^^xsd:string) "2'-deoxyguanosine 5'-triphosphate diphosphohydrolase"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dgf"^^xsd:string) Annotation( "KEGG:R01855"^^xsd:string) Annotation( "PMID:17090528"^^xsd:string) Annotation( "PMID:22531138"^^xsd:string) "Catalysis of the reaction: dGTP + H2O = dGMP + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dTTP diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dgf"^^xsd:string) Annotation( "PMID:22531138"^^xsd:string) "Catalysis of the reaction: dTTP + H2O = dTMP + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dgf"^^xsd:string) Annotation( "KEGG:R00426"^^xsd:string) Annotation( "PMID:22531138"^^xsd:string) "Catalysis of the reaction: GTP + H2O = GMP + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "GTP diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "GTP diphosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R00426"^^xsd:string) "GTP diphosphohydrolase (diphosphate-forming); guanosine 5'-triphosphate pyrophosphohydrolase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ITP diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dgf"^^xsd:string) Annotation( "KEGG:R00720"^^xsd:string) Annotation( "PMID:17899088"^^xsd:string) Annotation( "PMID:22531138"^^xsd:string) "Catalysis of the reaction: ITP + H2O = IMP + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R00720"^^xsd:string) "inosine-5'-triphosphate pyrophosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dgf"^^xsd:string) Annotation( "KEGG:R00662"^^xsd:string) Annotation( "PMID:17899088"^^xsd:string) "Catalysis of the reaction: UTP + H2O = UMP + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R00662"^^xsd:string) "uridine triphosphate pyrophosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UTP diphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dgf"^^xsd:string) Annotation( "PMID:22531138"^^xsd:string) "Catalysis of the reaction: XTP + H2O = xanthosine 5'-phosphate + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R02720"^^xsd:string) "XTP pyrophosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "XTP diphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acyl-glucuronidase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:22294686"^^xsd:string) "acyl-glucuronide deglucuronidation activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) Annotation( "PMID:22294686"^^xsd:string) "Catalysis of the reaction: an acyl-glucuronoside + H2O = an alcohol + D-glucuronate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "gallate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.57"^^xsd:string) Annotation( "PMID:16030014"^^xsd:string) "Catalysis of the reaction: gallate + O2 = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "taxoid 7beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.147"^^xsd:string) "Catalysis of the reaction: taxusin + O2 + NADPH + H+ = 7beta-hydroxytaxusin + NADP+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "succinate-semialdehyde dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.79"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) "Catalysis of the reaction: succinate semialdehyde + NADP+ + H2O = succinate + NADPH + 2 H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.79"^^xsd:string) "succinyl semialdehyde dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.79"^^xsd:string) "NADP-dependent succinate-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.79"^^xsd:string) "succinic semialdehyde dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.79"^^xsd:string) "succinate semialdehyde:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:22120533"^^xsd:string) "Catalysis of the reaction: L-DOPA + O2 = ? + H2O. This reaction catalyzes the oxygenation of the dopamine precursor L-DOPA, to the corresponding o-quinone."^^xsd:string) AnnotationAssertion(rdfs:label "L-DOPA monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:22120533"^^xsd:string) "Catalysis of the reaction: dopamine + O2 = ? + H2O. This reaction catalyzes the oxygenation of dopamine to the corresponding o-quinone."^^xsd:string) AnnotationAssertion(rdfs:label "dopamine monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "PMID:22847818"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + adenine(2030) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(2030) in 23S rRNA."^^xsd:string) AnnotationAssertion(rdfs:label "23S rRNA (adenine(2030)-N(6))-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "16S rRNA (guanine(1516)-N(2))-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "PMID:22079366"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1516) in 16S rRNA = N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:21078962"^^xsd:string) Annotation( "PMID:22704558"^^xsd:string) Annotation( "PMID:22705370"^^xsd:string) Annotation( "PMID:22759634"^^xsd:string) "Catalysis of the ATP-dependent rewinding of single-stranded DNA (ssDNA) to reform base pairs between strands. Often acts on ssDNA bubbles bound by replication protein A (RPA)."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "nucleoside-triphosphatase activity involved in DNA annealing"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) "ATP-dependent DNA annealing activity"^^xsd:string) AnnotationAssertion(rdfs:label "annealing helicase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "annealing activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "chitin disaccharide deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.105"^^xsd:string) "chitin oligosaccharide amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.105"^^xsd:string) "chitin oligosaccharide deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.105"^^xsd:string) Annotation( "GOC:imk"^^xsd:string) "Catalysis of the reaction: 2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-2-deoxy-beta-D-glucopyranose + H2O = 2-(acetylamino)-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-beta-D-glucopyranose + acetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.105"^^xsd:string) "chitobiose amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:20505341"^^xsd:string) "Interacting selectively and non-covalently with a regulatory subunit of phosphatidylinositol 3-kinase. The regulatory subunit associates with the catalytic subunit to regulate both its activity and subcellular location."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "PI3K regulatory subunit binding"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol 3-kinase regulatory subunit binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10627473"^^xsd:string) Annotation( "PMID:20505341"^^xsd:string) "p85 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:17475214"^^xsd:string) "Interacting selectively and non-covalently with the catalytic subunit of a phosphatidylinositol 3-kinase. The catalytic subunit catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol 3-kinase catalytic subunit binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "PI3K catalytic subunit binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17475214"^^xsd:string) "p110 binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:21408223"^^xsd:string) Annotation( "PMID:22908287"^^xsd:string) "VPg unlinkase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:21408223"^^xsd:string) "Y-pUpN PDE activity"^^xsd:string) AnnotationAssertion(rdfs:label "tyrosyl-RNA phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:21408223"^^xsd:string) "unlinkase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:21408223"^^xsd:string) "uridylylpolynucleotide-(5' P->O)- tyrosine phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:21408223"^^xsd:string) Annotation( "PMID:22908287"^^xsd:string) "Catalysis of the hydrolysis of a 5' tyrosyl-RNA phosphodiester bond between a protein and RNA. In picornaviruses, this covalent bond connects VPg, a viral-encoded protein essential for RNA replication, to the 5' end of all nascent picornavirus genomes; it is cleaved from viral RNA prior to its engaging in protein synthesis."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peptide pheromone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:38579"^^xsd:string) Annotation( "GOC:al"^^xsd:string) "Combining with a peptide pheromone, and transmitting the signal across the membrane to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:64120"^^xsd:string) "M-factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:7941744"^^xsd:string) "M-factor mating pheromone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:64120"^^xsd:string) Annotation( "GOC:al"^^xsd:string) "Combining with the mating-type peptide pheromone M-factor and transmitting the signal across the membrane to initiate a change in cell activity. M-factor is a nine-membered oligopeptide that consists of tyrosyl, threonyl, prolyl, lysyl, valyl, prolyl, tyrosyl, methionyl and methyl S-farnesylcysteinate residues joined in sequence, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Minus."^^xsd:string) AnnotationAssertion(rdfs:label "mating-type M-factor pheromone receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:64120"^^xsd:string) Annotation( "GOC:al"^^xsd:string) "Combining with the mating-type peptide pheromone P-factor and transmitting the signal across the membrane to initiate a change in cell activity. P-factor is a polypeptide of 23 residues, with the sequence Thr-Tyr-Ala-Asp-Phe-Leu-Arg-Ala-Tyr-Gln-Ser-Trp-Asn-Thr-Phe-Val-Asn-Pro-Asp-Arg-Pro-Asn-Leu, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Plus."^^xsd:string) AnnotationAssertion(rdfs:label "mating-type P-factor pheromone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8314086"^^xsd:string) Annotation( "PMID:8861202"^^xsd:string) "P-factor mating pheromone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:64121"^^xsd:string) "P-factor receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PR:000017284"^^xsd:string) Annotation( "Wikipedia:VEGF-A"^^xsd:string) "Combining with vascular endothelial growth factor A (VEGF-A) and transmitting the signal across the plasma membrane to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "VEGF-A-activated receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PR:000017284"^^xsd:string) "vascular endothelial growth factor A-activated receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PR:000003096"^^xsd:string) Annotation( "Wikipedia:VEGF-B"^^xsd:string) "Combining with vascular endothelial growth factor B (VEGF-B) and transmitting the signal across the plasma membrane to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PR:000003096"^^xsd:string) "vascular endothelial growth factor B-activated receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "VEGF-B-activated receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "VEGF-C-activated receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PR:000017285"^^xsd:string) "VEGFC-activated receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PR:000017285"^^xsd:string) Annotation( "Wikipedia:VEGF-C"^^xsd:string) "Combining with vascular endothelial growth factor C (VEGF-C) and transmitting the signal across the plasma membrane to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PR:000017285"^^xsd:string) "vascular endothelial growth factor C-activated receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PR:000007520"^^xsd:string) Annotation( "Wikipedia:VEGF-D"^^xsd:string) "C-fos induced growth factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PR:000007520"^^xsd:string) "vascular endothelial growth factor D-activated receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PR:000017285"^^xsd:string) "VEGFD-activated receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "VEGF-D-activated receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PR:000007520"^^xsd:string) Annotation( "Wikipedia:VEGF-D"^^xsd:string) "Combining with vascular endothelial growth factor D (VEGF-D) and transmitting the signal across the plasma membrane to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "VEGF-E-activated receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:19909239"^^xsd:string) "Combining with vascular endothelial growth factor E (VEGF-E) and transmitting the signal across the plasma membrane to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "PMID:19909239"^^xsd:string) "vascular endothelial growth factor E-activated receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "placental growth factor-activated receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12871269"^^xsd:string) "PlGF receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "placental growth factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:uh"^^xsd:string) Annotation( "PMID:12871269"^^xsd:string) "PlGF-activated receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:uh"^^xsd:string) Annotation( "PMID:12871269"^^xsd:string) Annotation( "PMID:7929268"^^xsd:string) Annotation( "PR:000012605"^^xsd:string) Annotation( "Wikipedia:Placental_growth_factor"^^xsd:string) "Combining with placental growth factor (PlGF) and transmitting the signal across the plasma membrane to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydantoin racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.99.5"^^xsd:string) Annotation( "InterPro:IPR015942"^^xsd:string) "Catalysis of the reaction: D-5-monosubstituted hydantoin = L-5-monosubstituted hydantoin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:crds"^^xsd:string) Annotation( "InterPro:IPR005903"^^xsd:string) Annotation( "MetaCyc:RXN-8787"^^xsd:string) Annotation( "PMID:8437569"^^xsd:string) "Catalysis of the reaction: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a = bacteriochlorophyllide a + 2 H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.99.19"^^xsd:string) Annotation( "GOC:crds"^^xsd:string) Annotation( "MetaCyc:RXN-11319"^^xsd:string) Annotation( "PMID:17403671"^^xsd:string) "Catalysis of the reaction: L-tyrosine + S-adenosyl-L-methionine + reduced acceptor = 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + acceptor + 2 H+."^^xsd:string) AnnotationAssertion(rdfs:label "2-iminoacetate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:9811660"^^xsd:string) "cDPGS activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyclic 2,3-diphosphoglycerate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "CPGS activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:crds"^^xsd:string) Annotation( "PMID:2226838"^^xsd:string) Annotation( "PMID:8320225"^^xsd:string) Annotation( "PMID:9811660"^^xsd:string) "Catalysis of the reaction: 2,3-diphosphoglycerate (DPG) + ATP = cyclic 2,3-diphosphoglycerate (cDPG) + ADP + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "InterPro:IPR020872"^^xsd:string) Annotation( "PMID:2226838"^^xsd:string) Annotation( "PMID:8159166"^^xsd:string) "Catalysis of the reaction: 2-phosphoglycerate + ATP = 2,3-diphosphoglycerate + ADP."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "2PGK activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-phosphoglycerate kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "racemase activity, acting on amino acids and derivatives"^^xsd:string) AnnotationAssertion(Annotation( "GOC:crds"^^xsd:string) "Catalysis of the interconversion of the two enantiomers of a chiral amino acid or amino acid derivative."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:crds"^^xsd:string) Annotation( "PMID:11222605"^^xsd:string) Annotation( "PMID:22750871"^^xsd:string) Annotation( "PMID:8682792"^^xsd:string) "Accepts activated D-alanine and subsequently transfers D-alanine onto a teichoic acid acceptor molecule. The carrier protein provides an essential link between the D-alanine-D-alanyl carrier protein ligase and the incorporation of D-alanine into the substrate."^^xsd:string) AnnotationAssertion(rdfs:label "D-alanyl carrier activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:crds"^^xsd:string) Annotation( "PMID:11222605"^^xsd:string) "D-alanyl carrier protein"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.-"^^xsd:string) "type-2 mutarotase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.-"^^xsd:string) "alpha-L-fucose 1-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:crds"^^xsd:string) Annotation( "PMID:15060078"^^xsd:string) Annotation( "RHEA:25583"^^xsd:string) "Catalysis of the reaction: alpha-L-fucose = beta-L-fucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.-"^^xsd:string) "fucose 1-epimerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-fucose mutarotase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutathione hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.19.13"^^xsd:string) Annotation( "GOC:imk"^^xsd:string) "Catalysis of the reaction: glutathione + H2O = L-cysteinylglycine + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.19.13"^^xsd:string) "glutathionase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.19.13"^^xsd:string) "gamma-glutamyltranspeptidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.33"^^xsd:string) "UDP-N-acetyl-D-glucosamine:ditrans,octacis-undecaprenyl phosphate N-acetyl-D-glucosaminephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.33"^^xsd:string) Annotation( "GOC:rs"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + ditrans,octacis-undecaprenyl phosphate = UMP + N-acetyl-alpha-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.33"^^xsd:string) "UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.33"^^xsd:string) "GlcNAc-P-P-Und synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.33"^^xsd:string) "UDP-N-acetylglucosamine:undecaprenyl-phosphate GlcNAc-1-phosphate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.33"^^xsd:string) "UDP-GIcNAc:undecaprenyl phosphate N-acetylglucosaminyl 1-P transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.3.6"^^xsd:string) "PdxST activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.3.6"^^xsd:string) "pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.3.6"^^xsd:string) Annotation( "GOC:rs"^^xsd:string) "Catalysis of the reaction: D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H2O + phosphate. The reaction occurs in two steps: L-glutamine + H2O = L-glutamate + NH3, and subsequently D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3 = pyridoxal 5'-phosphate + 4 H2O + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "flavin reductase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.36"^^xsd:string) Annotation( "GOC:rs"^^xsd:string) "Catalysis of the reaction: reduced flavin + NAD+ = flavin + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.36"^^xsd:string) "flavin:NADH oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.36"^^xsd:string) "NADH-dependent flavin reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.12"^^xsd:string) Annotation( "GOC:rs"^^xsd:string) "Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cytidine diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) "CDPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) "Catalysis of the reaction: CDP + H2O = CMP + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12626341"^^xsd:string) Annotation( "Wikipedia:Lactoperoxidase"^^xsd:string) "lactoperoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pm"^^xsd:string) Annotation( "PMID:12626341"^^xsd:string) "Catalysis of the reaction: thiocyanate (SCN-) + hydrogen peroxide (H2O2) = hypothiocyanite (OSCN-) + 2 H2O. Catalyzes the hydrogen peroxide oxidation of thiocyanate."^^xsd:string) AnnotationAssertion(rdfs:label "thiocyanate peroxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "formate dehydrogenase (quinone) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.6"^^xsd:string) "formate:quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.6"^^xsd:string) "formate dehydrogenase-N activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.6"^^xsd:string) "Fdh-N activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.6"^^xsd:string) Annotation( "GOC:bm"^^xsd:string) "Catalysis of the reaction: formate + a quinone = CO2 + a quinol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12372405"^^xsd:string) Annotation( "PMID:21440021"^^xsd:string) "sNPF receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "short neuropeptide F receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ha"^^xsd:string) Annotation( "PMID:16330127"^^xsd:string) Annotation( "PMID:21440021"^^xsd:string) "Combining with a short neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Short neuropeptide F is an arthropod peptide of less than 28 residues (as small as 8-10 residues in some species) with a C-terminal RFamide or LRFamide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ha"^^xsd:string) Annotation( "PMID:12951076"^^xsd:string) Annotation( "PMID:19186060"^^xsd:string) "Combining with a pyrokinin and transmitting the signal within the cell to induce a change in cell activity. Pyrokinins are a group of insect neuropeptides that share the common C-terminal pentapeptide sequence Phe-X-Pro-Arg-Leu-NH2 (X = S, T, K, A, or G). They play a central role in diverse physiological processes including stimulation of gut motility, production and release of sex pheromones, diapause, and pupariation."^^xsd:string) AnnotationAssertion(Annotation( "PMID:17065249"^^xsd:string) "PK receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyrokinin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:rb"^^xsd:string) "proteasome channel gating activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "ATPase involved in positive regulation of proteasomal protein catabolic process"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "proteasomal ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rb"^^xsd:string) "proteasome channel opening activity"^^xsd:string) AnnotationAssertion(rdfs:label "proteasome-activating ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rb"^^xsd:string) Annotation( "PMID:11430818"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "KEGG:R07053"^^xsd:string) "8-lipoxygenase (S-type)"^^xsd:string) AnnotationAssertion(rdfs:label "arachidonate 8(S)-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.-"^^xsd:string) Annotation( "GOC:lb"^^xsd:string) Annotation( "PMID:10625675"^^xsd:string) "Catalysis of the reaction: arachidonate + O(2) = (5Z,8S,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "8(S)-lipoxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone acetyltransferase activity (H3-K14 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:21289066"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 14) = CoA + histone H3 N6-acetyl-L-lysine (position 14)."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "histone lysine N-acetyltransferase activity (H3-K14 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "PMID:23935849"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + oxalate = acetate + oxalyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "acetyl-CoA:oxalate CoA-transferase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.30"^^xsd:string) "heptaprenyl pyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.30"^^xsd:string) Annotation( "RHEA:27797"^^xsd:string) "Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate = 4 diphosphate + all-trans-heptaprenyl diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.30"^^xsd:string) "HepPP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.30"^^xsd:string) "heptaprenyl pyrophosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.30"^^xsd:string) "all-trans-heptaprenyl-diphosphate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "heptaprenyl diphosphate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.83"^^xsd:string) "hexaprenyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.83"^^xsd:string) "hexaprenyl pyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.83"^^xsd:string) Annotation( "RHEA:27562"^^xsd:string) "Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate = 3 diphosphate + all-trans-hexaprenyl diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "RHEA:21211"^^xsd:string) "Catalysis of the reaction: O-phospho-L-serine + H2O <=> L-serine + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "L-phosphoserine phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-phosphoserine phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:24876"^^xsd:string) "Catalysis of the reaction: O-phospho-D-serine + H2O <=> L-serine + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "RHEA:28121"^^xsd:string) "Catalysis of the reaction: ditrans,octacis-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate+ GDP."^^xsd:string) AnnotationAssertion(rdfs:label "ditrans, polycis-undecaprenyl-phosphate mannosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "all-trans-undecaprenyl-phosphate mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:12784"^^xsd:string) "Catalysis of the reaction: all-trans-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate + GDP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "adenosylcobinamide kinase (GTP-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:15768"^^xsd:string) "Catalysis of the reaction: adenosylcobinamide + GTP = adenosylcobinamide phosphate + GDP + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "adenosylcobinamide kinase (ATP-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:15772"^^xsd:string) "Catalysis of the reaction: adenosylcobinamide + ATP = adenosylcobinamide phosphate + ADP + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CMP kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:11603"^^xsd:string) "Catalysis of the reaction: ATP + CMP = ADP + CDP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "RHEA:25097"^^xsd:string) "Catalysis of the reaction: ATP + dCMP = ADP + dCDP."^^xsd:string) AnnotationAssertion(rdfs:label "dCMP kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R01665"^^xsd:string) "ATP:dCMP phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "all-trans undecaprenol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:23755"^^xsd:string) "Catalysis of the reaction: ATP + undecaprenol + all-trans-undecaprenyl phosphate + ADP + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "di-trans, poly-cis-undecaprenol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:61216"^^xsd:string) "ditrans,polycis-undecaprenol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:28125"^^xsd:string) "Catalysis of the reaction: di-trans, octa-cis-undecaprenol + ATP = di-trans,octa-cis-undecaprenyl phosphate + ADP + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nitronate monooxygenase (FMN-linked) activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:26461"^^xsd:string) "Catalysis of the reaction: ethylnitronate + FMNH(2) + O(2) = acetaldehyde + FMN + H(2)O + H(+) + nitrite."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "K48-linked polyubiquitin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:20739285"^^xsd:string) "Interacting selectively and non-covalently and non-covalently with a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "RHEA:11099"^^xsd:string) "Catalysis of the reaction: glycerol 3-phosphate + NADP+ = glycerone phosphate + H+ + NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "glycerol-3-phosphate dehydrogenase [NADP+] activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "citrate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:16848"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "RHEA:18984"^^xsd:string) "Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "2-dehydropantolactone reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "proton-transporting ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydrogen-exporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:20855"^^xsd:string) "Catalysis of the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dermatan 6-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.33"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "KEGG:R07288"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bhm"^^xsd:string) "Catalysis of the transfer of a iron-sulfur cluster from one compound (donor) to another (acceptor)."^^xsd:string) AnnotationAssertion(rdfs:label "iron-sulfur transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Fe-S transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-methionine-(S)-S-oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) Annotation( "RHEA:19995"^^xsd:string) "Catalysis of the reaction: L-methionine (S)-S-oxide + thioredoxin -> L-methionine + thioredoxin disulfide + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PR:000008534"^^xsd:string) "HGF binding"^^xsd:string) AnnotationAssertion(Annotation( "PR:000008534"^^xsd:string) "Interacting selectively and non-covalently with a hepatocyte growth factor."^^xsd:string) AnnotationAssertion(rdfs:label "hepatocyte growth factor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ubiquitinyl hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.19.12"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:ka"^^xsd:string) "Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.19.12"^^xsd:string) "ubiquitin C-terminal hydrolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.19.12"^^xsd:string) "ubiquitinyl hydrolase 1 activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "netrin receptor activity involved in positive chemotaxis"^^xsd:string) AnnotationAssertion(rdfs:label "netrin receptor activity involved in chemoattraction"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell towards a higher concentration of netrin."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "attractive netrin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:9102398"^^xsd:string) Annotation( "Wikipedia:Leptin_receptor"^^xsd:string) "Combining with the fat-cell specific hormone leptin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "leptin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:21041441"^^xsd:string) "G-protein coupled odorant receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:21041441"^^xsd:string) "odorant receptor activity, G-protein coupled"^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled olfactory receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:21041441"^^xsd:string) "Combining with an odorant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "olfactory receptor activity, G-protein coupled"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "signalling receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Receiving a signal and transmitting the signal in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "receptor activity involved in signal transduction"^^xsd:string) AnnotationAssertion(rdfs:label "signaling receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0123645387"^^xsd:string) Annotation( "PMID:12671190"^^xsd:string) "endocytic receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12671190"^^xsd:string) "receptor activity involved in ligand uptake"^^xsd:string) AnnotationAssertion(rdfs:label "cargo receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "transport receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:15239958"^^xsd:string) "Combining selectively with an extracellular macromolecule and delivering the macromolecule into the cell via endocytosis."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "receptor activity involved in receptor-mediated endocytosis"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "reelin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:12827279"^^xsd:string) Annotation( "PMID:20223215"^^xsd:string) Annotation( "PR:000013879"^^xsd:string) "Combining with the secreted glycoprotein reelin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "PR:000013879"^^xsd:string) "reeler receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sphingosine-1-phosphate receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "Wikipedia:Sphingosine_1-phosphate"^^xsd:string) "S1P receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:12728273"^^xsd:string) Annotation( "Wikipedia:S1PR1"^^xsd:string) "Combining with the sphingolipid sphingosine-1-phosphate (S1P), and transmitting the signal across the membrane by activating an associated G-protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "delta-opioid receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "Wikipedia:Enkephalin"^^xsd:string) "Combining with an enkephalin, and transmitting the signal across the membrane by activating an associated G-protein. A enkephalin is a pentapeptide (Tyr-Gly-Gly-Phe-Met or Tyr-Gly-Gly-Phe-Leu) involved in regulating nociception in the body."^^xsd:string) AnnotationAssertion(rdfs:label "enkephalin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:17303"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) "Combining with morphine (17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol), and transmitting the signal across the membrane by activating an associated G-protein."^^xsd:string) AnnotationAssertion(rdfs:label "morphine receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "mu-opioid receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "kappa-opioid receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "Wikipedia:Dynorphin"^^xsd:string) "Combining with a dynorphin peptide, and transmitting the signal across the membrane by activating an associated G-protein. Dynorphin is any opioid peptide that is generated by cleavage of the precursor protein prodynorphin."^^xsd:string) AnnotationAssertion(rdfs:label "dynorphin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "GOC:txnOH"^^xsd:string) "Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. For example, some steroid hormone receptors bind to transcription factor complexes to regulate transcription of genes whose promoters do not contain hormone response elements."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "ligand-activated nuclear receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "ligand-activated RNA polymerase II transcription factor binding transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "ligand-dependent transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "glucocorticoid receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucocorticoid-activated sequence-specific DNA binding RNA polymerase II transcription factor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:17689856"^^xsd:string) "Combining with a glucocorticoid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:17689856"^^xsd:string) "Combining with a glucocorticoid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. For example, glucocorticoid-bound receptors can bind to transcription factor complexes to regulate transcription of genes whose promoters do not contain glucocorticoid response elements."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "glucocorticoid receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "estrogen nuclear receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:17615392"^^xsd:string) "Combining with estrogen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II."^^xsd:string) AnnotationAssertion(rdfs:label "estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "estrogen nuclear receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:17615392"^^xsd:string) "Combining with estrogen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. For example, estrogen-bound receptors can bind to transcription factor complexes to regulate transcription of genes whose promoters do not contain estrogen response elements."^^xsd:string) AnnotationAssertion(rdfs:label "estrogen-activated RNA polymerase II transcription factor binding transcription factor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:17379646"^^xsd:string) Annotation( "PMID:20960099"^^xsd:string) "Combining with estrogen and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled estrogen receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sl"^^xsd:string) Annotation( "PR:000002107"^^xsd:string) "CD254 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sl"^^xsd:string) Annotation( "PR:000002107"^^xsd:string) "ODF binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sl"^^xsd:string) Annotation( "PR:000002107"^^xsd:string) "TNF-related activation-induced cytokine binding"^^xsd:string) AnnotationAssertion(Annotation( "PR:000002107"^^xsd:string) "tumor necrosis factor ligand superfamily member 11 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:cjm"^^xsd:string) Annotation( "PR:000002107"^^xsd:string) "Interacting selectively and non-covalently with tumor necrosis factor ligand superfamily member 11 (TNFSF11), a member of the tumor necrosis factor (TNF) cytokine family."^^xsd:string) AnnotationAssertion(rdfs:label "TNFSF11 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sl"^^xsd:string) Annotation( "PR:000002107"^^xsd:string) "TRANCE binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sl"^^xsd:string) Annotation( "PR:000002107"^^xsd:string) "receptor activator of nuclear factor kappa-B ligand binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sl"^^xsd:string) Annotation( "PR:000002107"^^xsd:string) "osteoclast differentiation factor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "tumor necrosis factor superfamily member 11 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "tumor necrosis factor (ligand) superfamily member 11 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sl"^^xsd:string) Annotation( "PR:000002107"^^xsd:string) "OPGL binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sl"^^xsd:string) Annotation( "PR:000002107"^^xsd:string) "osteoprotegerin ligand binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sl"^^xsd:string) Annotation( "PR:000002107"^^xsd:string) "RANKL binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:cjm"^^xsd:string) Annotation( "PR:000002107"^^xsd:string) "Combining with a tumor necrosis factor ligand superfamily member 11 (TNFSF11) and transmitting the signal across the cell membrane to initiate a change in cell activity or function."^^xsd:string) AnnotationAssertion(Annotation( "PR:000002107"^^xsd:string) Annotation( "Wikipedia:RANKL"^^xsd:string) "tumor necrosis factor ligand superfamily member 11 receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "TNFSF11 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PR:000002107"^^xsd:string) Annotation( "Wikipedia:RANKL"^^xsd:string) "RANKL receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "protein tyrosine kinase collagen receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:uh"^^xsd:string) Annotation( "PMID:16626936"^^xsd:string) Annotation( "PMID:21568710"^^xsd:string) "Combining with collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate."^^xsd:string) AnnotationAssertion(Annotation( "PMID:21568710"^^xsd:string) "collagen RTK activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16626936"^^xsd:string) "discoidin domain receptor"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:21568710"^^xsd:string) "transmembrane collagen receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:uh"^^xsd:string) Annotation( "PMID:21568710"^^xsd:string) "Combining with a collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "collagen receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) "MAP kinase activity involved in cell wall integrity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis."^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "MAPK activity involved in cell wall biogenesis"^^xsd:string) AnnotationAssertion( "MAP kinase activity involved in cell wall biogenesis"^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase activity involved in cell wall organization or biogenesis"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) "MAP kinase kinase activity involved in cell wall biogenesis"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "MAP2K activity involved in cell wall integrity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "MAPKK activity involved in cell wall integrity"^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase kinase activity involved in cell wall organization or biogenesis"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10523653"^^xsd:string) "Mpk1 phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase phosphatase activity involved in regulation of cell wall biogenesis"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to cell wall biogenesis."^^xsd:string) AnnotationAssertion(Annotation( "PMID:10523653"^^xsd:string) "Slt2 phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) "MAP kinase kinase kinase activity involved in cell wall biogenesis"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "MAPKKK activity involved in cell wall integrity"^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase kinase kinase activity involved in cell wall organization or biogenesis"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "MAP3K activity involved in cell wall integrity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to conjugation with cellular fusion."^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase activity involved in conjugation with cellular fusion"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "MAPK activity involved in conjugation with cellular fusion"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "MAP2K activity involved in conjugation with cellular fusion"^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase kinase activity involved in conjugation with cellular fusion"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "MAPKK activity involved in conjugation with cellular fusion"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to conjugation with cellular fusion."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "MAPKKK activity involved in conjugation with cellular fusion"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to cell wall biogenesis."^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase kinase kinase activity involved in conjugation with cellular fusion"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "MAP3K activity involved in conjugation with cellular fusion"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "MAPK phosphatase activity involved in regulation of conjugation with cellular fusion"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to conjugation with cellular fusion."^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase phosphatase activity involved in regulation of conjugation with cellular fusion"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to an innate immune response."^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase activity involved in innate immune response"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "MAPK activity involved in innate immune response"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "MAP kinase kinase activity involved in innate immune response"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "MAP2K activity involved in innate immune response"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "MAPKK activity involved in innate immune response"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to an innate immune response."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "MAPKKK activity involved in innate immune response"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to an innate immune response."^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase kinase kinase activity involved in innate immune response"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "MAP3K activity involved in innate immune response"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "MAP kinase phosphatase activity involved in regulation of innate immune response"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "MAPK phosphatase activity involved in regulation of innate immune response"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to an innate immune response."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "MAP kinase activity involved in osmosensory signalling pathway"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "MAPK activity involved in osmosensory signaling pathway"^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase activity involved in osmosensory signaling pathway"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "MAP kinase kinase activity involved in osmosensory signalling pathway"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "MAP2K activity involved in osmosensory signaling pathway"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway."^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "MAPKK activity involved in osmosensory signaling pathway"^^xsd:string) AnnotationAssertion(rdfs:label "MAP kinase kinase activity involved in osmosensory signaling pathway"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "MAP kinase kinase kinase activity involved in osmosensory signaling pathway"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "MAPKKK activity involved in osmosensory signaling pathway"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "MAP3K activity involved in osmosensory signaling pathway"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "MAP kinase kinase kinase activity involved in osmosensory signalling pathway"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "MAP kinase phosphatase activity involved in regulation of osmosensory signaling pathway"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "MAPK phosphatase activity involved in regulation of osmosensory signaling pathway"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "MAP kinase phosphatase activity involved in regulation of osmosensory signalling pathway"^^xsd:string) AnnotationAssertion(Annotation( "PMID:20880736"^^xsd:string) "Hog1 phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "VEGF binding"^^xsd:string) AnnotationAssertion(rdfs:label "vascular endothelial growth factor binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17470632"^^xsd:string) Annotation( "PR:000003096"^^xsd:string) Annotation( "PR:000007520"^^xsd:string) Annotation( "PR:000017284"^^xsd:string) Annotation( "PR:000017285"^^xsd:string) "Interacting selectively and non-covalently with a vascular endothelial growth factor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:20629020"^^xsd:string) Annotation( "PR:000000105"^^xsd:string) "Interacting selectively and non-covalently with a nodal protein, a member of the transforming growth factor-beta superfamily."^^xsd:string) AnnotationAssertion(rdfs:label "nodal binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "activin receptor antagonist activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:15062104"^^xsd:string) "Interacting with an activin receptor complex to reduce the action of another ligand, the agonist. A receptor antagonist does not initiate signaling upon binding to a receptor, but instead blocks an agonist from binding to the receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:15062104"^^xsd:string) "Interacting with an activin receptor to reduce the action of the agonist nodal. A receptor antagonist does not initiate signaling upon binding to a receptor, but instead blocks an agonist from binding to the receptor."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "nodal antagonist activity"^^xsd:string) AnnotationAssertion(rdfs:label "activin receptor antagonist activity involved in negative regulation of nodal signaling pathway"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "activin receptor antagonist activity involved in negative regulation of nodal signalling pathway"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "Wikilpedia:Human_chorionic_gonadotropin"^^xsd:string) "chorionic gonadotrophin binding"^^xsd:string) AnnotationAssertion(Annotation( "Wikipedia:Human_chorionic_gonadotropin"^^xsd:string) "chorionic gonadotropin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) Annotation( "Wikipedia:Human_chorionic_gonadotropin"^^xsd:string) "Interacting selectively and non-covalently with choriogonadotropin hormone, a heterodimer, with an alpha subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and thyroid-stimulating hormone (TSH), and a unique beta subunit."^^xsd:string) AnnotationAssertion(rdfs:label "choriogonadotropin hormone binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "C-C motif chemokine 19 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:15059845"^^xsd:string) Annotation( "PR:000001991"^^xsd:string) "Combining with the C-C motif chemokine 19 (CCL19) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "PMID:15059845"^^xsd:string) "CCL19 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "C-C motif chemokine 21 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:15059845"^^xsd:string) Annotation( "PR:000001993"^^xsd:string) "Combining with the C-C motif chemokine 21 (CCL21) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "PMID:15059845"^^xsd:string) Annotation( "PR:000001993"^^xsd:string) "CCL21 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "PR:000002094"^^xsd:string) "CCL5 receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "C-C motif chemokine 5 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PR:000002094"^^xsd:string) "small inducible cytokine A5 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PR:000002094"^^xsd:string) "Combining with the C-C motif chemokine 5 (CCL5) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "RANTES receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16460914"^^xsd:string) "NRG1 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16460914"^^xsd:string) "NRG receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:16460914"^^xsd:string) Annotation( "PMID:20672328"^^xsd:string) "Combining with a neuregulin, a member of the EGF family of growth factors, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "neuregulin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16460914"^^xsd:string) "NRG2 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Interacting selectively and non-covalently with a neuregulin, a member of the EGF family of growth factors."^^xsd:string) AnnotationAssertion(rdfs:label "neuregulin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:22204316"^^xsd:string) "CXCR4"^^xsd:string) AnnotationAssertion(rdfs:label "C-X-C motif chemokine 12 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:22204316"^^xsd:string) "Combining with the C-X-C motif chemokine 12 (CXCL12) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "CXCL12 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "HGNC:10672"^^xsd:string) Annotation( "PR:000006066"^^xsd:string) "SDF-1 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "HGNC:10672"^^xsd:string) Annotation( "PR:000006066"^^xsd:string) "stromal cell-derived factor-1 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:22204316"^^xsd:string) "CXCR7"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "CCL2 receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "C-C motif chemokine 2 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with the C-C motif chemokine 2 (CCL2) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thrombopoietin receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:19630807"^^xsd:string) "Combining with the glycoprotein thrombopoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-17A receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:jc"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PR:000001138"^^xsd:string) "Combining with the cytokine interleukin-17A and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:pr"^^xsd:string) "death receptor activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_apoptosis"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) "Interacting with a death receptor such that the proportion of death receptors in an active form is increased. Ligand binding to a death receptor often induces a conformational change to activate the receptor."^^xsd:string) AnnotationAssertion(rdfs:label "death receptor agonist activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "bile acid receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:3098"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:10334992"^^xsd:string) Annotation( "PMID:12718893"^^xsd:string) "Combining with a bile acid and transmitting the signal to initiate a change in cell activity. A bile acid is any member of a group of steroid carboxylic acids occurring in bile."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:12524422"^^xsd:string) Annotation( "Wikipedia:G_protein-coupled_bile_acid_receptor"^^xsd:string) "Combining with an extracellular bile acid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."^^xsd:string) AnnotationAssertion(Annotation( "PMID:12419312"^^xsd:string) "membrane bile acid receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled bile acid receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "cell surface bile acid receptor"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:16325"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:12016314"^^xsd:string) Annotation( "PMID:12419312"^^xsd:string) "Combining with lithocholic acid and transmitting the signal to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "lithocholic acid receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10334992"^^xsd:string) "LCA receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "pattern recognition receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ar"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "Wikipedia:Pattern_recognition_receptor"^^xsd:string) "Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species, or damage-associated molecular pattern (DAMP), an endogenous molecule released from damaged cells), to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "Wikipedia:Pattern_recognition_receptor"^^xsd:string) "PRR activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:23871893"^^xsd:string) "Interacting selectively and non-covalently with a member of the neuropilin family."^^xsd:string) AnnotationAssertion(Annotation( "PMID:12852851"^^xsd:string) "neuropilin-binding"^^xsd:string) AnnotationAssertion(rdfs:label "neuropilin binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:23871893"^^xsd:string) "Nrp binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:23871893"^^xsd:string) "Nrp ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:15917797"^^xsd:string) "Combining with auxin and transmitting the signal in the cell to initiate a change in cell activity. Auxin is a plant hormone (phytohormone)."^^xsd:string) AnnotationAssertion(rdfs:label "auxin receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:24012247"^^xsd:string) "C2H4 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:22467798"^^xsd:string) "ethylene response sensor"^^xsd:string) AnnotationAssertion(rdfs:label "ethylene receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:22467798"^^xsd:string) Annotation( "PMID:24012247"^^xsd:string) "Combining with ethylene and transmitting the signal in the cell to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "ethylene receptor histidine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:22467798"^^xsd:string) "Combining with ethylene and transmitting the signal within the cell to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "RIG-I binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) "DDX58 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) "DDX58/RIG-I binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:21233210"^^xsd:string) "Interacting selectively and non-covalently with RIG-I, a cytosolic pattern recognition receptor that initiates an antiviral signaling pathway upon binding to viral RNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19019954"^^xsd:string) "Interacting selectively and non-covalently with MDA-5, a cytosolic pattern recognition receptor that initiates an antiviral signaling pathway upon binding to viral dsRNA."^^xsd:string) AnnotationAssertion(rdfs:label "MDA-5 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "MDA5 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:22046136"^^xsd:string) "Any endoribonuclease activity that contributes to the viral-induced catabolism of host mRNA."^^xsd:string) AnnotationAssertion(rdfs:label "endoribonuclease activity involved in viral induction of host mRNA catabolic process"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "TBP-class protein binding involved in viral suppression of host transcription initiation from RNA polymerase II promoter"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:11968006"^^xsd:string) "Selective and non-covalent interaction of a viral protein with a member of the class of TATA-binding proteins (TBP) in the host, including any of the TBP-related factors (TRFs), which contributes to the viral-suppression of assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "TFIIB-class transcription factor binding involved in viral suppression of host transcription initiation from RNA polymerase II promoter"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:18768974"^^xsd:string) "Selective and non-covalent interaction of a viral protein with a member of the TFIIB-class of host transcription factors, which contributes to the viral-suppression of assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA translocase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bm"^^xsd:string) Annotation( "PMID:22713318"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded RNA molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bm"^^xsd:string) Annotation( "PMID:17501915"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded DNA molecule, that contributes to the packing of viral DNA into a capsid."^^xsd:string) AnnotationAssertion(rdfs:label "DNA translocase activity involved in viral DNA genome packaging"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bm"^^xsd:string) "viral DNA packaging activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17501915"^^xsd:string) "viral DNA packaging motor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bm"^^xsd:string) Annotation( "PMID:22297533"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded RNA molecule, which contributes to the packaging of viral RNA into a nucleocapsid."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bm"^^xsd:string) "viral RNA packaging activity"^^xsd:string) AnnotationAssertion(rdfs:label "RNA translocase activity involved in viral RNA genome packaging"^^xsd:string) AnnotationAssertion(Annotation( "PMID:22297533"^^xsd:string) "RNA packaging ATPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "The action of a molecule that contributes to the structural integrity of a virion."^^xsd:string) AnnotationAssertion(Annotation( "UniProtKB-KW:KW-0468"^^xsd:string) "viral matrix protein"^^xsd:string) AnnotationAssertion(rdfs:label "structural constituent of virion"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "co-receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with a coreceptor. A coreceptor acts in cooperation with a primary receptor to transmit a signal within the cell."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-18 binding"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-18 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-18."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-18 receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-18 receptor activity"^^xsd:string) AnnotationAssertion( "IL-18R"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-18 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-15."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-15 binding"^^xsd:string) AnnotationAssertion( "IL-15 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-15 receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-15 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-15 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "IL-15R"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-16 binding"^^xsd:string) AnnotationAssertion( "IL-16 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-16."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-16 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-16 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-16 receptor activity"^^xsd:string) AnnotationAssertion( "IL-16R"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "IL-19 binding"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-19 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-19."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-19R"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-19 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-19 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-19 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-20."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-20 binding"^^xsd:string) AnnotationAssertion( "IL-20 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-20R"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-20 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-20 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-20 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-22 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-22."^^xsd:string) AnnotationAssertion( "IL-22 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-22R"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-22 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-22 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-22 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "IL-23 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with interleukin-23."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-23 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-23R"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-23 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-23 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-23 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "GM-CSF complex binding"^^xsd:string) AnnotationAssertion(rdfs:label "granulocyte macrophage colony-stimulating factor complex binding"^^xsd:string) AnnotationAssertion( "granulocyte macrophage colony stimulating factor complex binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the granulocyte macrophage colony-stimulating factor complex."^^xsd:string) AnnotationAssertion( "GMC-SF complex binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "adenosinetriphosphatase inhibitor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of ATP to ADP and orthophosphate."^^xsd:string) AnnotationAssertion(rdfs:label "ATPase inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "neurexin family protein binding"^^xsd:string) AnnotationAssertion( "neuroligin"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) Annotation( "PMID:18923512"^^xsd:string) "Interacting selectively and non-covalently with neurexins, synaptic cell surface proteins related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.43"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or lysine residue."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histone methylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "histone methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "attractant"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a higher concentration of that signal."^^xsd:string) AnnotationAssertion(rdfs:label "chemoattractant activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:2716741"^^xsd:string) "Combining with a leucokinin, any of several octapeptide hormones found in insects, and transmitting the signal to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "leucokinin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate."^^xsd:string) AnnotationAssertion(rdfs:label "5,10-methylenetetrahydrofolate-dependent methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydrofolate."^^xsd:string) AnnotationAssertion(rdfs:label "5-methyltetrahydrofolate-dependent methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydropteroyltri-L-glutamate."^^xsd:string) AnnotationAssertion(rdfs:label "5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a methyl group to an acceptor molecule, dependent on the presence of 5-methyl-5,6,7,8-tetrahydromethanopterin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the splitting and linkage of glucan molecules, resulting in glucan chain elongation."^^xsd:string) AnnotationAssertion(rdfs:label "glucanosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:10809732"^^xsd:string) "Catalysis of the splitting and linkage of (1->3)-beta-D-glucan molecules, resulting in (1->3)-beta-D-glucan chain elongation."^^xsd:string) AnnotationAssertion(rdfs:label "1,3-beta-glucanosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thiamine phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "thiamin phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:197075"^^xsd:string) "Catalysis of the hydrolysis of thiamine phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fructose 1,6-bisphosphate 1-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.11"^^xsd:string) "D-fructose 1,6-diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.11"^^xsd:string) "D-fructose-1,6-bisphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.11"^^xsd:string) "hexose diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.11"^^xsd:string) "Catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.11"^^xsd:string) "hexose bisphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.11"^^xsd:string) "fructose bisphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.11"^^xsd:string) "fructose 1,6-bisphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.11"^^xsd:string) "fructose 1,6-diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.11"^^xsd:string) "fructose diphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.11"^^xsd:string) "hexosediphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.11"^^xsd:string) "FBPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.11"^^xsd:string) "fructose 1,6-diphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.00"^^xsd:string) "fructose-bisphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.11"^^xsd:string) "D-fructose-1,6-bisphosphate 1-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.11"^^xsd:string) "fructose diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.11"^^xsd:string) "fructose 1,6-bisphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.11"^^xsd:string) "fructose-1,6-bisphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "rRNA primary transcript binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with an unprocessed ribosomal RNA transcript."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "SO:0000624"^^xsd:string) "Interacting selectively and non-covalently with a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end."^^xsd:string) AnnotationAssertion(rdfs:label "telomeric DNA binding"^^xsd:string) AnnotationAssertion( "telomere binding"^^xsd:string) AnnotationAssertion( "telomeric repeat binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "NKSFp40 binding"^^xsd:string) AnnotationAssertion( "IL-12p40 binding"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-12 beta subunit binding"^^xsd:string) AnnotationAssertion( "CLMFp40 binding"^^xsd:string) AnnotationAssertion( "IL-12B binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the beta subunit of interleukin-12."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-12 alpha subunit binding"^^xsd:string) AnnotationAssertion( "IL-12p35 binding"^^xsd:string) AnnotationAssertion( "NKSFp35 binding"^^xsd:string) AnnotationAssertion( "IL-12A binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the alpha subunit of interleukin-12."^^xsd:string) AnnotationAssertion( "CLMFp35 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell."^^xsd:string) AnnotationAssertion(rdfs:label "neurotransmitter binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions."^^xsd:string) AnnotationAssertion(rdfs:label "acetylcholine binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "Pfam:PF00017"^^xsd:string) "Interacting selectively and non-covalently with a SH2 domain (Src homology 2) of a protein, a protein domain of about 100 amino-acid residues and belonging to the alpha + beta domain class."^^xsd:string) AnnotationAssertion(rdfs:label "SH2 domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lysophosphatidic acid acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ab"^^xsd:string) Annotation( "PMID:16369050"^^xsd:string) "Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidic acid to form phosphatidic acid."^^xsd:string) AnnotationAssertion(Annotation( "PMID:16369050"^^xsd:string) "LPAAT activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:2172209"^^xsd:string) "Catalysis of the conversion of cobyrinic acid to cobyrinic acid a,c-diamide via the intermediate formation of cobyrinic acid c-monoamide."^^xsd:string) AnnotationAssertion(rdfs:label "cobyrinic acid a,c-diamide synthase activity"^^xsd:string) AnnotationAssertion( "CobB"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:21440021"^^xsd:string) "NPF receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "neuropeptide F receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:ma"^^xsd:string) Annotation( "PMID:21440021"^^xsd:string) "Combining with neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Neuropeptide F is an arthropod peptide of more than 28 residues (typically 28-45) with a consensus C-terminal RxRFamide (commonly RPRFa, but also RVRFa."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds."^^xsd:string) AnnotationAssertion(rdfs:label "peptide binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nitrite reductase (cytochrome, ammonia-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.2"^^xsd:string) "nitrite reductase (cytochrome; ammonia-forming)"^^xsd:string) AnnotationAssertion( "cytochrome c nitrite reductase activity"^^xsd:string) AnnotationAssertion( "multiheme nitrite reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.2"^^xsd:string) "cytochrome c552 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.2"^^xsd:string) "ammonia:ferricytochrome-c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.2"^^xsd:string) "Catalysis of the reaction: NH3 + 2 H2O + 6 ferricytochrome c = nitrite + 6 ferrocytochrome c + 7 H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "MetaCyc:RXN-5470"^^xsd:string) "Catalysis of the addition of the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol."^^xsd:string) AnnotationAssertion(rdfs:label "dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroxymethylglutaryl-CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.88"^^xsd:string) "3-hydroxy-3-methylglutaryl coenzyme A reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.88"^^xsd:string) "3-hydroxy-3-methylglutaryl-coenzyme A reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.88"^^xsd:string) "beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.88"^^xsd:string) "hydroxymethylglutaryl-CoA reductase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.88"^^xsd:string) Annotation( "RHEA:14836"^^xsd:string) "Catalysis of the reaction: (R)-mevalonate + CoA + 2 NAD(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.88"^^xsd:string) "(R)-mevalonate:NAD+ oxidoreductase (CoA-acylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.88"^^xsd:string) "HMG-CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.88"^^xsd:string) "hydroxymethylglutaryl coenzyme A reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.88"^^xsd:string) "beta-hydroxy-beta-methylglutaryl CoA-reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-5471"^^xsd:string) Annotation( "PMID:12480927"^^xsd:string) "Catalysis of the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol."^^xsd:string) AnnotationAssertion( "dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12417141"^^xsd:string) "Catalysis of the introduction of a trans double bond between C4 and C5 of the long chain base region of a sphingolipid. Sphingolipids are composed of a long chain base (LCB) amide-linked to a very long chain fatty acid."^^xsd:string) AnnotationAssertion(rdfs:label "sphingolipid delta-4 desaturase activity"^^xsd:string) AnnotationAssertion( "delta-4 sphingolipid desaturase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a xylosyl group to an acceptor molecule, typically another carbohydrate or a lipid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.3.8"^^xsd:string) "(S)-4-amino-5-oxopentanoate 4,5-aminomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.3.8"^^xsd:string) Annotation( "RHEA:14268"^^xsd:string) "Catalysis of the reaction: (S)-4-amino-5-oxopentanoate = 5-aminolevulinate."^^xsd:string) AnnotationAssertion(rdfs:label "glutamate-1-semialdehyde 2,1-aminomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.3.8"^^xsd:string) "glutamate-1-semialdehyde aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "MHC protein binding"^^xsd:string) AnnotationAssertion( "major histocompatibility complex ligand"^^xsd:string) AnnotationAssertion( "major histocompatibility complex binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with major histocompatibility complex molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "gamma-delta T cell receptor activity"^^xsd:string) AnnotationAssertion( "T cell receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with major histocompatibility complex class I molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation."^^xsd:string) AnnotationAssertion(rdfs:label "MHC class I protein binding"^^xsd:string) AnnotationAssertion( "major histocompatibility complex class I binding"^^xsd:string) AnnotationAssertion( "alpha-beta T cell receptor activity"^^xsd:string) AnnotationAssertion( "major histocompatibility complex class I ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "major histocompatibility complex class II ligand"^^xsd:string) AnnotationAssertion(rdfs:label "MHC class II protein binding"^^xsd:string) AnnotationAssertion( "major histocompatibility complex class II binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with major histocompatibility complex class II molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the activation of the small ubiquitin-related modifier URM1, through the formation of an ATP-dependent high-energy thiolester bond."^^xsd:string) AnnotationAssertion(rdfs:label "URM1 activating enzyme activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Hub1 activating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the activation of the small ubiquitin-related modifier Hub1, through the formation of an ATP-dependent high-energy thiolester bond."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "URM1 conjugating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12826404"^^xsd:string) "Catalysis of the covalent attachment of the ubiquitin-like protein URM1 to other proteins or other substrate molecules."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12826404"^^xsd:string) "Catalysis of the covalent attachment of the ubiquitin-like protein ISG15 to other proteins."^^xsd:string) AnnotationAssertion( "ISG15 conjugating enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "ISG15 ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lupeol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18033581"^^xsd:string) "oxidosqualene:lupeol cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-111"^^xsd:string) Annotation( "PMID:9883589"^^xsd:string) "Catalysis of the reaction: (S)-2,3-epoxysqualene = lupeol. This reaction is the cyclization of (S)-2,3-epoxysqualene (2,3-oxidosqualene) to lupeol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:9746369"^^xsd:string) "Catalysis of the reaction: (S)-2,3-epoxysqualene = beta-amyrin. This reaction is the cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into beta-amyrin."^^xsd:string) AnnotationAssertion(Annotation( "PMID:18033581"^^xsd:string) "oxidosqualene:beta-amyrin cyclase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-amyrin synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphate ion binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "structural constituent of cuticle"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "The action of a molecule that contributes to the structural integrity of a cuticle."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bacteriochlorophyll binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0192800981"^^xsd:string) "Interacting selectively and non-covalently with bacteriochlorophyll, a form of chlorophyll found in photosynthetic bacteria, such as the purple and green bacteria. There are several types, designated a to g. Bacteriochlorophyll a and bacteriochlorophyll b are structurally similar to the chlorophyll a and chlorophyll b found in plants."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "hypocretin receptor ligand"^^xsd:string) AnnotationAssertion( "orexin receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "hypocretin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "PMID:11988773"^^xsd:string) "Interacting selectively and non-covalently with the hypocretin receptor."^^xsd:string) AnnotationAssertion( "orexin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "heparin N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion( "heparan sulphate N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "heparan sulfate N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ma"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + heparan sulfate = UDP + (N-acetyl-D-glucosaminyl)-heparan sulfate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "structural constituent of collagen and cuticulin-based cuticle"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_sensu"^^xsd:string) "The action of a molecule that contributes to the structural integrity of a collagen and cuticulin-based cuticle. An example of this process is found in Caenorhabditis elegans."^^xsd:string) AnnotationAssertion( "structural constituent of cuticle"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "dirigent protein"^^xsd:string) AnnotationAssertion(rdfs:label "guiding stereospecific synthesis activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ma"^^xsd:string) "The orientation of free radical substrates in such a way that only a particular stereoisomer is synthesized by an enzyme. Best characterized as a function during lignan biosynthesis."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.187"^^xsd:string) "GDP-4-keto-6-deoxy-D-mannose reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "GDP-4-dehydro-D-rhamnose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.187"^^xsd:string) "GDP-4-keto-D-rhamnose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.187"^^xsd:string) "guanosine diphosphate-4-keto-D-rhamnose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.187"^^xsd:string) "GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "BRENDA:1.1.1.187"^^xsd:string) Annotation( "EC:1.1.1.187"^^xsd:string) "Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4 epimer is formed."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "chemokine receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "chemokine receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with any chemokine receptor."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming)"^^xsd:string) AnnotationAssertion(rdfs:label "hydroxymethylbutenyl pyrophosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:js"^^xsd:string) "Catalysis of the formation of both isopentenyl pyrophosphate and dimethylallyl pyrophosphate from (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "omega-3 fatty acid desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:9037020"^^xsd:string) "Catalysis of the introduction of an omega-3 double bond into the fatty acid hydrocarbon chain."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:11331102"^^xsd:string) "Catalysis of the reaction: sphingosine 1-phosphate + H2O = sphingosine + phosphate."^^xsd:string) AnnotationAssertion( "SPPase activity"^^xsd:string) AnnotationAssertion( "SPP phosphatase activity"^^xsd:string) AnnotationAssertion( "sphingosine-1-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sphingosine-1-phosphate phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity."^^xsd:string) AnnotationAssertion(rdfs:label "histone binding"^^xsd:string) AnnotationAssertion( "histone-specific chaperone activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "caffeoyl-CoA O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.104"^^xsd:string) "S-adenosyl-L-methionine:caffeoyl-CoA 3-O-methyltransferase activity"^^xsd:string) AnnotationAssertion( "caffeoyl coenzyme A methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.104"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + caffeoyl-CoA = S-adenosyl-L-homocysteine + feruloyl-CoA."^^xsd:string) AnnotationAssertion( "caffeoyl-CoA 3-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.104"^^xsd:string) "trans-caffeoyl-CoA 3-O-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.14"^^xsd:string) "6-carboxyhexanoyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.14"^^xsd:string) "6-carboxyhexanoate:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.14"^^xsd:string) "pimelyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.14"^^xsd:string) Annotation( "RHEA:14784"^^xsd:string) "Catalysis of the reaction: ATP + CoA + pimelate = AMP + diphosphate + H(+) + pimelyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "6-carboxyhexanoate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.14"^^xsd:string) "pimeloyl-CoA synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:1339261"^^xsd:string) "Catalysis of the reduction of versicolorin A to sterigmatocystin."^^xsd:string) AnnotationAssertion(rdfs:label "versicolorin reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) "bacterial triacyl lipoprotein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) "bacterial triacyl lipopeptide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "PMID:12077222"^^xsd:string) Annotation( "PMID:12524386"^^xsd:string) Annotation( "PMID:2757794"^^xsd:string) "Interacting selectively and non-covalently with a lipopeptide containing a nonprotein moiety consisting of three acyl groups."^^xsd:string) AnnotationAssertion(rdfs:label "triacyl lipopeptide binding"^^xsd:string) AnnotationAssertion( "triacylated lipopeptide binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "PMID:12077222"^^xsd:string) Annotation( "PMID:12524386"^^xsd:string) Annotation( "PMID:2757794"^^xsd:string) "Interacting selectively and non-covalently with a lipopeptide containing a nonprotein moiety consisting of two acyl groups."^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) "bacterial diacyl lipoprotein binding"^^xsd:string) AnnotationAssertion( "diacylated lipopeptide binding"^^xsd:string) AnnotationAssertion(rdfs:label "diacyl lipopeptide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) "bacterial diacyl lipopeptide binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aspartic endopeptidase activity, intramembrane cleaving"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain, occurring within the plasma membrane."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "eEF-2 kinase regulator"^^xsd:string) AnnotationAssertion(rdfs:label "eukaryotic elongation factor-2 kinase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:11904175"^^xsd:string) "Modulates the activity of the enzyme eukaryotic elongation factor-2 kinase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "eEF-2 kinase activator"^^xsd:string) AnnotationAssertion(rdfs:label "eukaryotic elongation factor-2 kinase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:11904175"^^xsd:string) "Increases the activity of the enzyme eukaryotic elongation factor-2 kinase."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "MetaCyc:RXN-8434"^^xsd:string) Annotation( "PMID:10848960"^^xsd:string) "Catalysis of the reaction: (S)-2,3-epoxysqualene = alpha-amyrin. This reaction is a cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into alpha-amyrin."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-amyrin synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:24621"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone."^^xsd:string) AnnotationAssertion(rdfs:label "hormone binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lipid phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphoric ester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.88"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Catalysis of the reaction: formyl-L-methionyl peptide + H2O = formate + methionyl peptide."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.88"^^xsd:string) "PDF activity"^^xsd:string) AnnotationAssertion(rdfs:label "peptide deformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.88"^^xsd:string) "formyl-L-methionyl peptide amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.88"^^xsd:string) "polypeptide deformylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.30"^^xsd:string) "reduced-riboflavin:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.30"^^xsd:string) "flavin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.30"^^xsd:string) "riboflavine mononucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.30"^^xsd:string) "NADPH-dependent FMN reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.30"^^xsd:string) "Catalysis of the reaction: reduced riboflavin + NADP+ = riboflavin + NADPH + 2 H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.30"^^xsd:string) "NADPH-specific FMN reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.30"^^xsd:string) "NADPH2:riboflavin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.30"^^xsd:string) "NADPH:riboflavin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.30"^^xsd:string) "NADPH-FMN reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "riboflavin reductase (NADPH) activity"^^xsd:string) AnnotationAssertion( "NADPH-riboflavin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.30"^^xsd:string) "FMN reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.30"^^xsd:string) "riboflavin mononucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.30"^^xsd:string) "riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide phosphate) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.30"^^xsd:string) "NADPH dehydrogenase (riboflavin) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.30"^^xsd:string) "NADPH2 dehydrogenase (riboflavin)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.30"^^xsd:string) "NADPH-riboflavin reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "exogenous peptide antigen binding"^^xsd:string) AnnotationAssertion(rdfs:label "peptide antigen binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:rv"^^xsd:string) "Interacting selectively and non-covalently with an antigen peptide."^^xsd:string) AnnotationAssertion( "endogenous peptide antigen binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "T cell receptor binding"^^xsd:string) AnnotationAssertion( "T-lymphocyte receptor binding"^^xsd:string) AnnotationAssertion( "TCR binding"^^xsd:string) AnnotationAssertion( "T lymphocyte receptor binding"^^xsd:string) AnnotationAssertion( "T-cell receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with a T cell receptor, the antigen-recognizing receptor on the surface of T cells."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "MSH:D015704"^^xsd:string) "Interacting selectively and non-covalently with a CD4, a receptor found on the surface of T cells, monocytes and macrophages."^^xsd:string) AnnotationAssertion(rdfs:label "CD4 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "MSH:D016827"^^xsd:string) "Interacting selectively and non-covalently with a CD8, a receptor found on the surface of thymocytes and cytotoxic and suppressor T-lymphocytes."^^xsd:string) AnnotationAssertion(rdfs:label "CD8 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0120781859"^^xsd:string) "Interacting selectively and non-covalently with a CD70, a receptor found on the surface of most activated B cells and some activated T cells."^^xsd:string) AnnotationAssertion( "CD27 receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "CD70 receptor binding"^^xsd:string) AnnotationAssertion( "CD27L binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0120781859"^^xsd:string) "Interacting selectively and non-covalently with CD154, a receptor found on the surface of some activated lymphocytes."^^xsd:string) AnnotationAssertion( "CD40L binding"^^xsd:string) AnnotationAssertion(rdfs:label "CD154 receptor binding"^^xsd:string) AnnotationAssertion( "CD40 receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "non-chaperonin molecular chaperone ATPase activity"^^xsd:string) AnnotationAssertion( "chaperonin ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ATPase activity, coupled"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.4.9"^^xsd:string) "ATP phosphohydrolase (polypeptide-unfolding)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.4.9"^^xsd:string) "chaperonin"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane."^^xsd:string) AnnotationAssertion( "nucleoplasmin ATPase activity"^^xsd:string) AnnotationAssertion( "peroxisome-assembly ATPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ATPase activity, uncoupled"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) "adenylpyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction is not directly coupled to any other reaction."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of an ion from one side of a membrane to the other, driven by the reaction: ATP + H2O = ADP + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "ATPase activity, coupled to transmembrane movement of ions"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ABC-type efflux porter activity"^^xsd:string) AnnotationAssertion( "ABC-type efflux permease activity"^^xsd:string) AnnotationAssertion( "ATP-binding cassette (ABC) transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "ATPase activity, coupled to transmembrane movement of substances"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane."^^xsd:string) AnnotationAssertion( "ABC transporter"^^xsd:string) AnnotationAssertion( "mating pheromone exporter"^^xsd:string) AnnotationAssertion( "ATP-binding cassette transporter"^^xsd:string) AnnotationAssertion( "ATP binding cassette transporter"^^xsd:string) AnnotationAssertion( "ABC-type uptake permease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ecdysis-triggering hormone binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ma"^^xsd:string) "Combining with ecdysis-triggering hormone to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "ETH receptor"^^xsd:string) AnnotationAssertion(rdfs:label "ecdysis-triggering hormone receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "JUN kinase kinase kinase kinase activity"^^xsd:string) AnnotationAssertion( "JUNKKKK activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Catalysis of the phosphorylation and activation of JUN kinase kinase kinases (JNKKKs)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "MHC class II protein binding, via lateral surface"^^xsd:string) AnnotationAssertion( "major histocompatibility complex class II protein binding, via lateral surface"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the lateral surface of major histocompatibility complex class II molecules."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the antigen binding groove of major histocompatibility complex class II molecules."^^xsd:string) AnnotationAssertion(rdfs:label "MHC class II protein binding, via antigen binding groove"^^xsd:string) AnnotationAssertion( "major histocompatibility complex class II protein binding, via antigen binding groove"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "PH domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "Pfam:PF00169"^^xsd:string) "Interacting selectively and non-covalently with a PH domain (pleckstrin homology) of a protein, a domain of about 100 residues that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.86"^^xsd:string) "reduced nicotinamide adenine dinucleotide kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "NADH kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.86"^^xsd:string) "DPNH kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.86"^^xsd:string) "ATP:NADH 2'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.86"^^xsd:string) "reduced diphosphopyridine nucleotide kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.86"^^xsd:string) Annotation( "RHEA:12263"^^xsd:string) "Catalysis of the reaction: ATP + NADH = ADP + 2 H(+) + NADPH."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ecdysteroid 22-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12177427"^^xsd:string) "Catalysis of the hydroxylation of an ecdysteroid at carbon position 22."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12177427"^^xsd:string) "Catalysis of the hydroxylation of an ecdysteroid at carbon position 2."^^xsd:string) AnnotationAssertion(rdfs:label "ecdysteroid 2-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3'-tRNA processing endoribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.11"^^xsd:string) "3 tRNase activity"^^xsd:string) AnnotationAssertion( "tRNA 3' endonuclease activity"^^xsd:string) AnnotationAssertion( "3' tRNA processing endoribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.11"^^xsd:string) "Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule."^^xsd:string) AnnotationAssertion( "RNase Z activity"^^xsd:string) AnnotationAssertion( "ribonuclease Z activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.11"^^xsd:string) "tRNAse Z"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.11"^^xsd:string) "tRNA 3 endonuclease activity"^^xsd:string) AnnotationAssertion( "3' tRNase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "histone lysine N-methyltransferase activity (H4-K20 specific)"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12086618"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 20). This reaction is the addition of a methyl group onto lysine at position 20 of the histone H4 protein."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histone methylase activity (H4-K20 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone methyltransferase activity (H4-K20 specific)"^^xsd:string) AnnotationAssertion( "histone H4 lysine 20-specific methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone methyltransferase activity (H3-K4 specific)"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12086618"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 4). This reaction is the addition of a methyl group onto lysine at position 4 of the histone H3 protein."^^xsd:string) AnnotationAssertion( "histone H3 lysine 4-specific methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histone methylase activity (H3-K4 specific)"^^xsd:string) AnnotationAssertion( "histone lysine N-methyltransferase activity (H3-K4 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "polo kinase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ma"^^xsd:string) "Catalysis of the addition of a phosphate group onto a serine or threonine residue in any member of the polo kinase class of proteins."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "identical protein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with an identical protein or proteins."^^xsd:string) AnnotationAssertion( "protein homopolymerization"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17889655"^^xsd:string) "isoform-specific homophilic binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "dimerization activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with an identical protein to form a homodimer."^^xsd:string) AnnotationAssertion(rdfs:label "protein homodimerization activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "beta-actinin binding"^^xsd:string) AnnotationAssertion( "capZ binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with actinin, any member of a family of proteins that crosslink F-actin."^^xsd:string) AnnotationAssertion(rdfs:label "actinin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fucose binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:33984"^^xsd:string) Annotation( "ISBN:0582227089"^^xsd:string) "Interacting selectively and non-covalently with fucose, the pentose 6-deoxygalactose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:12637589"^^xsd:string) "Interacting selectively and non-covalently with the vitamin D receptor, a nuclear receptor that mediates the action of vitamin D by binding DNA and controlling the transcription of hormone-sensitive genes."^^xsd:string) AnnotationAssertion( "VDR binding"^^xsd:string) AnnotationAssertion(rdfs:label "vitamin D receptor binding"^^xsd:string) AnnotationAssertion( "calciferol receptor binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Wnt receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "Wnt-activated receptor activity"^^xsd:string) AnnotationAssertion( "frizzled receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Combining with a Wnt protein and transmitting the signal across the plasma membrane to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "frizzled-2 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the enzyme histone deacetylase."^^xsd:string) AnnotationAssertion(rdfs:label "histone deacetylase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peptidoglycan binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "PMID:14698226"^^xsd:string) "Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10893231"^^xsd:string) "Interacting selectively and non-covalently with the RNA element BRE (Bruno response element)."^^xsd:string) AnnotationAssertion(rdfs:label "BRE binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aldarate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "PMID:15034926"^^xsd:string) "Catalysis of the transfer of aldarate from one side of the membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:jsg"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of D-glucarate, the D-enantiomer of glucarate, from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "D-glucarate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aldonate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of aldonate from one side of the membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:jsg"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of D-glucuronate, the D-enantiomer of glucuronate, from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "D-glucuronate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-galactonate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:jsg"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of D-galactonate, the D-enantiomer of galactonate, from one side of the membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "amide transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "amine/amide/polyamine channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "molybdenum ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of molybdenum (Mo) ions from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3-phenylpropionate acid transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-phenylpropionic acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "hydrocinnamic acid transporter activity"^^xsd:string) AnnotationAssertion( "HCA transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of 3-phenylpropionic acid from one side of the membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "antibiotic transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Enables the directed movement of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms, into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:17698"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Enables the directed movement of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion(rdfs:label "chloramphenicol transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "polymyxin transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fosmidomycin transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:12543685"^^xsd:string) "Enables the directed movement of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arabinose transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:22599"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of arabinose, a pentose monosaccharide that occurs in both D and L configurations, and as a polymer, from one side of the membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arabinan transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of an arabinan, a polysaccharide composed of arabinose residues, from one side of the membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12024216"^^xsd:string) Annotation( "PMID:12486003"^^xsd:string) "Catalysis of the reaction: N-acetyl(alpha-tubulin) + H2O = alpha-tubulin + acetate."^^xsd:string) AnnotationAssertion(rdfs:label "tubulin deacetylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "xanthine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of xanthine from one side of a membrane to the other. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Enables the directed movement of a xenobiotic, a compound foreign to living organisms, into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion(rdfs:label "xenobiotic transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:36420"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Enables the directed movement of acridine (10-azaanthracene), a heterocyclic ring compound found in crude coal-tar anthracene, into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion(rdfs:label "acridine transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "colicin transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "PMID:17347522"^^xsd:string) "Catalysis of the transfer of a colicin from one side of a membrane to the other. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "PMID:9171417"^^xsd:string) "Catalysis of the transfer of group A colicins (colicins E1, E2, E3, A, K, and N) from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "group A colicin transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alkylphosphonate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Catalysis of the transfer of an alkylphosphonate from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:10899166"^^xsd:string) "Interacting selectively and non-covalently with one or more specific sites on a neuromedin U receptor."^^xsd:string) AnnotationAssertion(rdfs:label "neuromedin U receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "neuropeptide binding"^^xsd:string) AnnotationAssertion(Annotation( "http://www.wormbook.org/chapters/www_neuropeptides/neuropeptides.html"^^xsd:string) "Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "neuromedin U binding"^^xsd:string) AnnotationAssertion( "NMU binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:12584108"^^xsd:string) "Interacting selectively and non-covalently and stoichiometrically with neuromedin U, a hypothalamic peptide involved in energy homeostasis and stress responses."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "benzoate transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0721662544"^^xsd:string) "Enables the directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "m-hydroxyphenylpropionic acid transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxyphenylpropionic acid transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Enables the directed movement of 3-hydroxyphenylpropionic acid into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion( "3-(3-hydroxyphenyl)propionic acid transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "siderochrome transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Enables the directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion( "siderophore-iron transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "siderophore transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of a ferrichrome into, out of or within a cell, or between cells. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine."^^xsd:string) AnnotationAssertion(rdfs:label "ferrichrome transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "enterochelin transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "enterobactin transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:28855"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Enables the directed movement of the siderochrome enterochelin, a cyclic trimer of 2, 3 dihydroxybenzoylserine into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:8837459"^^xsd:string) "Enables the directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion(rdfs:label "chrysobactin transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "achromobactin transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Enables the directed movement of achromobactin, a citrate siderophore, into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dipeptide transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:46761"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Enables the directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tripeptide transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:47923"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Enables the directed movement of a tripeptide, a compound containing three amino acids linked together by peptide bonds, into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:jsg"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of D-amino acids from one side of a membrane to the other. D-amino acids are the D-enantiomers of amino acids."^^xsd:string) AnnotationAssertion( "D-amino acid transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-amino acid transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-alanine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "D-alanine transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15570"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of D-alanine from one side of a membrane to the other. D-alanine is the D-enantiomer of 2-aminopropanoic acid."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "D-serine permease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:jsg"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of D-serine from one side of a membrane to the other. D-serine is the D-enantiomer of 2-amino-3-hydroxypropanoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "D-serine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "D-serine transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of glucosides from one side of the membrane to the other. Glucosides are glycosides in which the sugar group is a glucose residue."^^xsd:string) AnnotationAssertion(rdfs:label "glucoside transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:17814"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "salicin transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "http://biotech.icmb.utexas.edu/"^^xsd:string) "Catalysis of the transfer of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "arbutin transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lipoprotein transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dextrin transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) Annotation( "http://www.mercksource.com/"^^xsd:string) "Catalysis of the transfer of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, from one side of the membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:15034926"^^xsd:string) Annotation( "http://www.mercksource.com/"^^xsd:string) "Catalysis of the transfer of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "maltodextrin transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alkanesulfonate transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Enables the directed movement of alkanesulfonate into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion( "alkanesulphonate transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "antimonite secondary active transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "antimonite porter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of antimonite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "antimonite-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.16"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + antimonite(in) = ADP + phosphate + antimonite(out)."^^xsd:string) AnnotationAssertion( "antimonite ABC transporter"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "acridine:proton antiporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "acridine:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10735876"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acridine(in) = H+(in) + acridine(out)."^^xsd:string) AnnotationAssertion( "acridine efflux pump activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "homoserine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "homoserine transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of homoserine from one side of a membrane to the other. Homoserine is alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:25000"^^xsd:string) Annotation( "GOC:go_curators"^^xsd:string) "Enables the directed movement of lactone from one side of a membrane to the other. A lactone is a cyclic ester of a hydroxy carboxylic acid, containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring."^^xsd:string) AnnotationAssertion(rdfs:label "lactone transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.73"^^xsd:string) "Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3) and (1->4) bonds."^^xsd:string) AnnotationAssertion(rdfs:label "licheninase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.73"^^xsd:string) "1,3;1,4-beta-glucan 4-glucanohydrolase activity"^^xsd:string) AnnotationAssertion( "lichenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.73"^^xsd:string) "beta-(1->3), (1->4)-D-glucan 4-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.73"^^xsd:string) "endo-beta-1,3-1,4 glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.73"^^xsd:string) "mixed linkage beta-glucanase activity"^^xsd:string) AnnotationAssertion( "1,3-1,4-beta-glucan 4-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.73"^^xsd:string) "1,3;1,4-beta-glucan endohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.73"^^xsd:string) "beta-glucanase activity"^^xsd:string) AnnotationAssertion( "1,3-1,4-beta-D-glucan 4-glucanohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "endo-1,3-beta-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.39"^^xsd:string) "endo-(1,3)-beta-D-glucanase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucan endo-1,3-beta-D-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.39"^^xsd:string) "endo-1,3-beta-D-glucanase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.39"^^xsd:string) "1,3-beta-D-glucan glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.39"^^xsd:string) "Catalysis of the hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.39"^^xsd:string) "callase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.39"^^xsd:string) "(1->3)-beta-glucan endohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.39"^^xsd:string) "1,3-beta-D-glucan 3-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.39"^^xsd:string) "beta-1,3-glucanase"^^xsd:string) AnnotationAssertion( "laminaranase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.39"^^xsd:string) "(1->3)-beta-glucan 3-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.39"^^xsd:string) "kitalase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.39"^^xsd:string) "endo-1,3-beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.39"^^xsd:string) "endo-(1->3)-beta-D-glucanase activity"^^xsd:string) AnnotationAssertion( "laminarinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.39"^^xsd:string) "oligo-1,3-glucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "retinoic acid receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:12476796"^^xsd:string) "Interacting selectively and non-covalently with the retinoic acid receptor, a ligand-regulated transcription factor belonging to the nuclear receptor superfamily."^^xsd:string) AnnotationAssertion( "RAR binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peroxisome proliferator activated receptor binding"^^xsd:string) AnnotationAssertion( "PPAR binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:12769781"^^xsd:string) "Interacting selectively and non-covalently with any of the peroxisome proliferator activated receptors, alpha, beta or gamma."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-ornithine carboxy-lyase activator activity"^^xsd:string) AnnotationAssertion(rdfs:label "ornithine decarboxylase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Upregulation of the activity of the enzyme ornithine decarboxylase."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "ornithine decarboxylase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Modulation of the activity of the enzyme ornithine decarboxylase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "X11L binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:12780348"^^xsd:string) "Interacting selectively and non-covalently with X11-like protein, a neuron-specific adaptor protein."^^xsd:string) AnnotationAssertion(rdfs:label "X11-like protein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) using energy from the hydrolysis of ATP."^^xsd:string) AnnotationAssertion(rdfs:label "ATP-dependent protein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-tubulin binding"^^xsd:string) AnnotationAssertion( "alpha tubulin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the microtubule constituent protein alpha-tubulin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "gamma-tubulin binding"^^xsd:string) AnnotationAssertion( "gamma tubulin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the microtubule constituent protein gamma-tubulin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "ribonucleoprotein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:go_curators"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with any complex of RNA and protein."^^xsd:string) AnnotationAssertion(rdfs:label "ribonucleoprotein complex binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "protein-RNA complex binding"^^xsd:string) AnnotationAssertion( "RNP binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ribosome binding"^^xsd:string) AnnotationAssertion( "ribosome receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with any part of a ribosome."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with any part of the larger ribosomal subunit."^^xsd:string) AnnotationAssertion(rdfs:label "ribosomal large subunit binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with any part of the small ribosomal subunit."^^xsd:string) AnnotationAssertion(rdfs:label "ribosomal small subunit binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_apoptosis"^^xsd:string) Annotation( "PMID:14744432"^^xsd:string) Annotation( "Wikipedia:Caspase"^^xsd:string) "Stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic process."^^xsd:string) AnnotationAssertion( "caspase inhibitor activity"^^xsd:string) AnnotationAssertion(rdfs:label "cysteine-type endopeptidase inhibitor activity involved in apoptotic process"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "caspase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mtg_apoptosis"^^xsd:string) Annotation( "PMID:14744432"^^xsd:string) Annotation( "Wikipedia:Caspase"^^xsd:string) "Modulates the activity of a cysteine-type endopeptidase involved in the apoptotic process."^^xsd:string) AnnotationAssertion(rdfs:label "cysteine-type endopeptidase regulator activity involved in apoptotic process"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chromatin insulator sequence binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:12783795"^^xsd:string) "Interacting selectively and non-covalently and stoichiometrically with a chromatin insulator sequence, a DNA sequence that prevents enhancer-mediated activation or repression of transcription."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0321000382"^^xsd:string) "Interacting selectively and non-covalently with single-stranded telomere-associated DNA."^^xsd:string) AnnotationAssertion(rdfs:label "single-stranded telomeric DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "telomeric ssDNA binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "RTS1 element binding"^^xsd:string) AnnotationAssertion( "RTS1 barrier binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:14645529"^^xsd:string) "Interacting selectively and non-covalently with replication fork barriers found in rDNA spacers, sites that inhibit replication forks in the direction opposite to rDNA transcription."^^xsd:string) AnnotationAssertion( "RFB binding"^^xsd:string) AnnotationAssertion(rdfs:label "rDNA spacer replication fork barrier binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "siroheme synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.76"^^xsd:string) "precorrin-2:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.76"^^xsd:string) "SirC"^^xsd:string) AnnotationAssertion( "1,3-dimethyluroporphyrinogen III dehydrogenase activity"^^xsd:string) AnnotationAssertion( "dihydrosirohydrochlorin dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.76"^^xsd:string) Annotation( "RHEA:15616"^^xsd:string) "Catalysis of the reaction: NAD(+) + precorrin-2 = 2 H(+) + NADH + sirohydrochlorin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.76"^^xsd:string) "Met8p"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.76"^^xsd:string) "precorrin-2 oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.76"^^xsd:string) "CysG"^^xsd:string) AnnotationAssertion(rdfs:label "precorrin-2 dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tumor necrosis factor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "http://lookwayup.com/"^^xsd:string) "Interacting selectively and non-covalently with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "neurotrophin-3 binding"^^xsd:string) AnnotationAssertion(rdfs:label "neurotrophin binding"^^xsd:string) AnnotationAssertion( "neurotrophin TRKC receptor activity"^^xsd:string) AnnotationAssertion( "NT4 binding"^^xsd:string) AnnotationAssertion( "neurotrophin TRKB receptor activity"^^xsd:string) AnnotationAssertion( "NT-4 binding"^^xsd:string) AnnotationAssertion( "NT 4/5 binding"^^xsd:string) AnnotationAssertion( "neurotrophin 4/5 binding"^^xsd:string) AnnotationAssertion( "neurotrophin 3 binding"^^xsd:string) AnnotationAssertion( "NT-5 binding"^^xsd:string) AnnotationAssertion( "NT3 binding"^^xsd:string) AnnotationAssertion( "NT5 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PR:000021998"^^xsd:string) Annotation( "http://www.mercksource.com/"^^xsd:string) "Interacting selectively and non-covalently with a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth."^^xsd:string) AnnotationAssertion( "neurotrophin TRKA receptor activity"^^xsd:string) AnnotationAssertion( "neurotrophin TRK receptor activity"^^xsd:string) AnnotationAssertion( "NT-3 binding"^^xsd:string) AnnotationAssertion( "neurotrophin-4/5 binding"^^xsd:string) AnnotationAssertion( "NT-4/5 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Neu/ErbB-2 receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "ErbB-3 class receptor binding"^^xsd:string) AnnotationAssertion( "HER3 receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the protein-tyrosine kinase receptor ErbB-3/HER3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ubiquitin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) "Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "PRPP pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10969"^^xsd:string) Annotation( "PMID:12370170"^^xsd:string) "Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + H2O = ribose 1,5 bisphosphate + phosphate + H+."^^xsd:string) AnnotationAssertion(rdfs:label "5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycerol-3-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the reaction: glycerol 3-phosphate + H2O = glycerol + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3'-5' DNA helicase activity"^^xsd:string) AnnotationAssertion( "3' to 5' DNA helicase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the unwinding of the DNA helix in the direction 3' to 5'."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5'-3' DNA helicase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the unwinding of the DNA helix in the direction 5' to 3'."^^xsd:string) AnnotationAssertion( "5' to 3' DNA helicase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the direction 3' to 5'."^^xsd:string) AnnotationAssertion( "ATP-dependent 3' to 5' DNA helicase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ATP-dependent 3'-5' DNA helicase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "DNA helicase IV activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the direction 5' to 3'."^^xsd:string) AnnotationAssertion(rdfs:label "ATP-dependent 5'-3' DNA helicase activity"^^xsd:string) AnnotationAssertion( "ATP-dependent 5' to 3' DNA helicase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ssDNA-dependent ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "single-stranded DNA-dependent ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single-stranded DNA, and it drives another reaction."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with ions, charged atoms or groups of atoms."^^xsd:string) AnnotationAssertion(rdfs:label "ion binding"^^xsd:string) AnnotationAssertion( "atom binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with anions, charged atoms or groups of atoms with a net negative charge."^^xsd:string) AnnotationAssertion(rdfs:label "anion binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cation binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with cations, charged atoms or groups of atoms with a net positive charge."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase core enzyme, containing a specific subunit composition defined as the core enzyme."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase core enzyme binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "amine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with any organic compound that is weakly basic in character and contains an amino or a substituted amino group."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with an organic acid, any acidic compound containing carbon in covalent linkage."^^xsd:string) AnnotationAssertion(rdfs:label "organic acid binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alcohol binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with an alcohol, any of a class of alkyl compounds containing a hydroxyl group."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:st"^^xsd:string) "Interacting selectively and non-covalently with vascular endothelial growth factor receptor 1."^^xsd:string) AnnotationAssertion( "VEGF receptor 1 binding"^^xsd:string) AnnotationAssertion( "Flt-1 binding"^^xsd:string) AnnotationAssertion( "VEGFR 1 binding"^^xsd:string) AnnotationAssertion(rdfs:label "vascular endothelial growth factor receptor 1 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "VEGFR 2 binding"^^xsd:string) AnnotationAssertion(rdfs:label "vascular endothelial growth factor receptor 2 binding"^^xsd:string) AnnotationAssertion( "VEGF receptor 2 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:st"^^xsd:string) "Interacting selectively and non-covalently with vascular endothelial growth factor receptor 2."^^xsd:string) AnnotationAssertion( "Flk-1 binding"^^xsd:string) AnnotationAssertion( "kinase domain region binding"^^xsd:string) AnnotationAssertion( "KDR binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "fms-like-tyrosine kinase (Flt)-4 binding"^^xsd:string) AnnotationAssertion( "VEGFR 3 binding"^^xsd:string) AnnotationAssertion(rdfs:label "vascular endothelial growth factor receptor 3 binding"^^xsd:string) AnnotationAssertion( "VEGF receptor 3 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:st"^^xsd:string) "Interacting selectively and non-covalently with vascular endothelial growth factor receptor 3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Interacting selectively and non-covalently with sulfate, SO4(2-), a negatively charged small molecule."^^xsd:string) AnnotationAssertion(rdfs:label "sulfate binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide."^^xsd:string) AnnotationAssertion(rdfs:label "glycosphingolipid binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Interacting selectively and non-covalently with alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group."^^xsd:string) AnnotationAssertion(rdfs:label "alkanesulfonate binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carbohydrate-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of carbohydrates across a membrane."^^xsd:string) AnnotationAssertion( "carbohydrate ABC transporter"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carbohydrate-exporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(in) -> ADP + phosphate + carbohydrate(out)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bacteriocin-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "bacteriocin ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of bacteriocins across a membrane."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the reaction: ATP + H2O + daunorubicin(in) = ADP + phosphate + daunorubicin(out)."^^xsd:string) AnnotationAssertion(rdfs:label "daunorubicin-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "daunorubicin ABC transporter"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "structural maintenance of chromosomes family protein binding"^^xsd:string) AnnotationAssertion(rdfs:label "SMC family protein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) Annotation( "InterPro:IPR024704"^^xsd:string) Annotation( "PMID:9640531"^^xsd:string) "Interacting selectively and non-covalently with any protein from the structural maintenance of chromosomes (SMC) family, a group of chromosomal ATPases with a role in mitotic chromosome organization."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "anion ABC transporter"^^xsd:string) AnnotationAssertion(rdfs:label "anion transmembrane-transporting ATPase activity"^^xsd:string) AnnotationAssertion( "anion-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + anion(out) = ADP + phosphate + anion(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "laminin-4 binding"^^xsd:string) AnnotationAssertion( "laminin-2 binding"^^xsd:string) AnnotationAssertion(rdfs:label "laminin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) "Interacting selectively and non-covalently with laminins, glycoproteins that are major constituents of the basement membrane of cells."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "laminin-1 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with laminin-1, a glycoprotein trimer with the subunit composition alpha1, beta1, gamma1."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Catalysis of the transfer of organic anions from one side of a membrane to the other, in a sodium dependent manner."^^xsd:string) AnnotationAssertion(rdfs:label "sodium-dependent organic anion transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) "ADPase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) "ATP-diphosphohydrolase activity"^^xsd:string) AnnotationAssertion( "adenosine diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) "ATP diphosphohydrolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) "ATP-diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "adenosinepyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.3"^^xsd:string) "ATP diphosphohydrolase (phosphate-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "adenosine-diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "ADPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.5"^^xsd:string) Annotation( "PMID:1470606"^^xsd:string) "Catalysis of the reaction: ADP + H2O = AMP + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CTPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Catalysis of the reaction: CTP + H2O = CDP + phosphate. May or may not be coupled to another reaction."^^xsd:string) AnnotationAssertion( "cytidine triphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with any phospholipase, enzymes that catalyze of the hydrolysis of a glycerophospholipid."^^xsd:string) AnnotationAssertion(rdfs:label "phospholipase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with poly(3-hydroxyalkanoate)s, polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria."^^xsd:string) AnnotationAssertion( "PHA binding"^^xsd:string) AnnotationAssertion(rdfs:label "poly(3-hydroxyalkanoate) binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutathione binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with glutathione; a tripeptide composed of the three amino acids cysteine, glutamic acid and glycine."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidylinositol-3,4-bisphosphate binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with phosphatidylinositol-3,4-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 4' positions."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-octaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kd"^^xsd:string) Annotation( "PMID:9045837"^^xsd:string) "Catalysis of the reaction: 2-octaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2-hexaprenyl-6-methoxy-1,4-benzoquinone methylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kd"^^xsd:string) Annotation( "PMID:9083048"^^xsd:string) "Catalysis of the reaction: 2-hexaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "TelN"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:11804598"^^xsd:string) "Catalysis of a site-specific breakage and reunion reaction that generates two hairpin telomeres from a replicated telomere substrate. Occurs via a two-step transesterification with a protein-DNA intermediate similar to that used by topoisomerases and site-specific recombinases."^^xsd:string) AnnotationAssertion( "ResT"^^xsd:string) AnnotationAssertion(rdfs:label "site-specific telomere resolvase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cardiolipin synthetase"^^xsd:string) AnnotationAssertion( "cardiolipin synthase"^^xsd:string) AnnotationAssertion(rdfs:label "CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the reaction: CDP-diacylglycerol + phosphatidylglycerol = CMP + diphosphatidylglycerol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:10960477"^^xsd:string) "Catalysis of the reaction: CTP + 2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate = CDP-2,3-di-O-geranylgeranyl-sn-glycerol."^^xsd:string) AnnotationAssertion(rdfs:label "CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity"^^xsd:string) AnnotationAssertion( "CDP-2,3-di-O-geranylgeranyl-sn-glycerol synthase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "catalysis of free radical formation"^^xsd:string) AnnotationAssertion( "catalysis of free-radical generation"^^xsd:string) AnnotationAssertion( "catalysis of free radical generation"^^xsd:string) AnnotationAssertion( "catalysis of free-radical biosynthesis"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of a reaction that generates a free radical, a highly reactive molecule with an unsatisfied electron valence pair."^^xsd:string) AnnotationAssertion( "catalysis of free-radical formation"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.97.1.4"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:18307109"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + dihydroflavodoxin + [formate C-acetyltransferase]-glycine = 5'-deoxyadenosine + L-methionine + flavodoxin semiquinone + [formate C-acetyltransferase]-glycin-2-yl radical."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.4"^^xsd:string) "formate C-acetyltransferase-glycine dihydroflavodoxin:S-adenosyl-L-methionine oxidoreductase (S-adenosyl-L-methionine cleaving)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.4"^^xsd:string) "PFL activase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[formate-C-acetyltransferase]-activating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.4"^^xsd:string) "formate acetyltransferase-glycine dihydroflavodoxin:S-adenosyl-L-methionine oxidoreductase (S-adenosyl-L-methionine cleaving) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.4"^^xsd:string) "formate-C-acetyltransferase-activating enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.4"^^xsd:string) "formate acetyltransferase activating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.4"^^xsd:string) "PFL-glycine:S-adenosyl-L-methionine H transferase (flavodoxin-oxidizing, S-adenosyl-L-methionine-cleaving) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.4"^^xsd:string) "[pyruvate formate-lyase]-activating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.4"^^xsd:string) "pyruvate formate-lyase-activating enzyme"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans."^^xsd:string) AnnotationAssertion(rdfs:label "proteoglycan binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit."^^xsd:string) AnnotationAssertion(rdfs:label "heparan sulfate proteoglycan binding"^^xsd:string) AnnotationAssertion( "heparin proteoglycan binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "HLH domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "Prosite:PDOC0038"^^xsd:string) "Interacting selectively and non-covalently with Helix Loop Helix, a domain of 40-50 residues that occurs in specific DNA-binding proteins that act as transcription factors. The domain is formed of two amphipathic helices joined by a variable length linker region that can form a loop and it mediates protein dimerization."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "initiator tRNA phosphoribosyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:7954819"^^xsd:string) "Catalysis of the transfer of a phosphoribosyl group from 5'-phosphoribosyl-1'-pyrophosphate to position 64 of initiator tRNA."^^xsd:string) AnnotationAssertion(rdfs:label "tRNA A64-2'-O-ribosylphosphate transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "corticotropin-releasing factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "CRF receptor activity"^^xsd:string) AnnotationAssertion( "adrenocorticotropin-releasing hormone receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "ISBN:0838577016"^^xsd:string) Annotation( "PMID:11027914"^^xsd:string) Annotation( "PMID:15134857"^^xsd:string) "Combining with corticotropin-releasing hormone and transmitting the signal to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "CRH receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "corticotropin-releasing hormone receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "PKB binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "http://www.heartandmetabolism.org/"^^xsd:string) "Interacting selectively and non-covalently with protein kinase B, an intracellular kinase that is important in regulating glucose metabolism."^^xsd:string) AnnotationAssertion(rdfs:label "protein kinase B binding"^^xsd:string) AnnotationAssertion( "Akt binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "phosphatidylinositol-3-phosphate-dependent protein kinase binding"^^xsd:string) AnnotationAssertion(rdfs:label "3-phosphoinositide-dependent protein kinase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with a 3-phosphoinositide-dependent protein kinase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein histidine kinase binding"^^xsd:string) AnnotationAssertion( "protein-histidine kinase binding"^^xsd:string) AnnotationAssertion( "histidine kinase binding"^^xsd:string) AnnotationAssertion( "histidine-protein kinase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with protein histidine kinase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:9144210"^^xsd:string) "Interacting selectively and non-covalently with any of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways."^^xsd:string) AnnotationAssertion(rdfs:label "bHLH transcription factor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "MRF binding"^^xsd:string) AnnotationAssertion( "MyoD binding"^^xsd:string) AnnotationAssertion( "myogenin binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10966875"^^xsd:string) "Interacting selectively and non-covalently with Myogenic Regulatory Factor (MRF), a member of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors."^^xsd:string) AnnotationAssertion( "Myf5 binding"^^xsd:string) AnnotationAssertion( "Mrf4 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:11583838"^^xsd:string) "Catalysis of the reaction: 2-heptaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-heptaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine."^^xsd:string) AnnotationAssertion(rdfs:label "2-heptaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity"^^xsd:string) AnnotationAssertion( "2-heptaprenyl-6-methoxy-1,4-benzoquinone methylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:11583838"^^xsd:string) "Catalysis of the reaction: 2-nonaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine."^^xsd:string) AnnotationAssertion(rdfs:label "2-nonaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity"^^xsd:string) AnnotationAssertion( "2-nonaprenyl-6-methoxy-1,4-benzoquinone methylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity"^^xsd:string) AnnotationAssertion( "2-decaprenyl-6-methoxy-1,4-benzoquinone methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:11583838"^^xsd:string) "Catalysis of the reaction: 2-decaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-decaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3-demethylubiquinone-9 3-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:11583838"^^xsd:string) Annotation( "PMID:1479344"^^xsd:string) "Catalysis of the reaction: 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine = ubiquinol + S-adenosyl-L-homocysteine."^^xsd:string) AnnotationAssertion(rdfs:label "2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase activity"^^xsd:string) AnnotationAssertion( "2-octaprenyl-6-hydroxy phenol methylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12886015"^^xsd:string) "Interacting selectively and non-covalently with an immunoglobulin of a D isotype."^^xsd:string) AnnotationAssertion(rdfs:label "IgD binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance."^^xsd:string) AnnotationAssertion(rdfs:label "ATPase activity, coupled to movement of substances"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "anchoring"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific location on the membrane."^^xsd:string) AnnotationAssertion( "LEGO") AnnotationAssertion(rdfs:label "protein anchor"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "kinetochore binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "http://www.mercksource.com/"^^xsd:string) "Interacting selectively and non-covalently with a kinetochore, a proteinaceous structure on a condensed chromosome, beside the centromere, to which the spindle fibers are attached."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "leucine zipper domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "InterPro:IPR002158"^^xsd:string) "Interacting selectively and non-covalently with a leucine zipper domain, a protein secondary structure exhibiting a periodic repetition of leucine residues at every seventh position over a distance covering eight helical turns."^^xsd:string) AnnotationAssertion( "leucine zipper binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "adenosine 5'-monophosphoramidate hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "adenosine 5'-monophosphoramidase activity"^^xsd:string) AnnotationAssertion( "adenosine 5' monophosphoramidase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11805111"^^xsd:string) "Catalysis of the reaction: adenosine 5'-monophosphoramidate = AMP + NH2. Other substrates include AMP-morpholidate, AMP-N-alanine methyl ester and AMP-alpha-acetyl lysine methyl ester."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "adenosine 5'-diphosphate binding"^^xsd:string) AnnotationAssertion(rdfs:label "ADP binding"^^xsd:string) AnnotationAssertion( "adenosine diphosphate binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with ADP, adenosine 5'-diphosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "angiostatin binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16043488"^^xsd:string) "Interacting selectively and non-covalently with angiostatin, a proteolytic product of plasminogen or plasmin containing at least one intact kringle domain, and which is an inhibitor of angiogenesis."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "InsP4 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with inositol 1,3,4,5 tetrakisphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "inositol 1,3,4,5 tetrakisphosphate binding"^^xsd:string) AnnotationAssertion( "IP4 binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "protein ser/thr kinase activator activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein serine/threonine kinase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Increases the activity of a protein serine/threonine kinase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group."^^xsd:string) AnnotationAssertion(rdfs:label "lipoamide binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Moco binding"^^xsd:string) AnnotationAssertion(Annotation( "ISSN:09498257"^^xsd:string) "Interacting selectively and non-covalently with the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands."^^xsd:string) AnnotationAssertion(rdfs:label "molybdopterin cofactor binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "PI3K binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "phosphoinositide 3-kinase binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10209156"^^xsd:string) Annotation( "PMID:9255069"^^xsd:string) "Interacting selectively and non-covalently with a phosphatidylinositol 3-kinase, any enzyme that catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol 3-kinase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with insulin, a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms."^^xsd:string) AnnotationAssertion(rdfs:label "insulin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IRS binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12829233"^^xsd:string) "Interacting selectively and non-covalently with any of the insulin receptor substrate (IRS) proteins, adaptor proteins that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex."^^xsd:string) AnnotationAssertion( "insulin receptor substrate [protein] binding"^^xsd:string) AnnotationAssertion(rdfs:label "insulin receptor substrate binding"^^xsd:string) AnnotationAssertion( "IRS [protein] binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "odorant transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Enables the directed movement of odorants, any substance capable of stimulating the sense of smell, into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding."^^xsd:string) AnnotationAssertion( "sequence specific DNA binding"^^xsd:string) AnnotationAssertion(rdfs:label "sequence-specific DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "structure specific DNA binding"^^xsd:string) AnnotationAssertion(rdfs:label "structure-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein self-association"^^xsd:string) AnnotationAssertion( "protein self association"^^xsd:string) AnnotationAssertion( "intramolecular protein binding"^^xsd:string) AnnotationAssertion( "protein self binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with a domain within the same polypeptide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu2+ = ADP + phosphate + Cu2+, directly driving the transport of the copper ions across a membrane."^^xsd:string) AnnotationAssertion(rdfs:label "copper-transporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16957230"^^xsd:string) "Catalysis of the reaction: 2-oxoisocaproate + CoA = (R)-2-hydroxyisocaproyl-CoA."^^xsd:string) AnnotationAssertion( "(R)-2-hydroxyisocaproate CoA-transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxyisocaproate CoA-transferase activity"^^xsd:string) AnnotationAssertion( "(R)-2-hydroxyisocaproate CoA transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:16957230"^^xsd:string) "Catalysis of the reaction: 2-oxoisocaproate + NADH + H+ = (R)-2-hydroxyisocaproate + NAD+."^^xsd:string) AnnotationAssertion(rdfs:label "(R)-2-hydroxyisocaproate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(R)-citramalate synthase activity"^^xsd:string) AnnotationAssertion( "citramalate synthase"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:9864346"^^xsd:string) "Catalysis of the reaction: pyruvate + acetyl-CoA + H2O = (R)-citramalate + CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "mtnW"^^xsd:string) AnnotationAssertion( "MasA"^^xsd:string) AnnotationAssertion( "DK-MTP-1-P enolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity"^^xsd:string) AnnotationAssertion( "E-1"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:R82-RXN"^^xsd:string) "Catalysis of the reaction: 2,3-diketo-5-methylthiopentyl-1-phosphate = H+ + 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate. 2,3-diketo-5-methylthiopentyl-1-phosphate is also known as DK-MTP-1-P, and 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate as HK-MTPenyl-1-P."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "HK-MTPenyl-1-P phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.77"^^xsd:string) Annotation( "IMG:01681"^^xsd:string) Annotation( "MetaCyc:R83-RXN"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate. 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate is also known as HK-MTPenyl-P, and 1,2-dihydroxy-3-keto-5-methylthiopentene as DHK-MTPene."^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:R83-RXN"^^xsd:string) "2-hydroxy-3-keto-5-methylthio-phosphopentene phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-1083"^^xsd:string) "Catalysis of the reaction: (R)-2-hydroxyglutaryl-CoA = H2O + glutaconyl-CoA."^^xsd:string) AnnotationAssertion( "(R)-2-hydroxyglutaryl-CoA dehydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxyglutaryl-CoA dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxymethylglutarate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.291"^^xsd:string) Annotation( "RHEA:15508"^^xsd:string) "Catalysis of the reaction: 2-(hydroxymethyl)glutarate + NAD(+) = 2-formylglutarate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.291"^^xsd:string) "(S)-2-hydroxymethylglutarate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion( "HgD"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN"^^xsd:string) "Catalysis of the reaction: 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol + O2 + H+ = 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:R125-RXN"^^xsd:string) Annotation( "PMID:13064"^^xsd:string) "Catalysis of the reaction: 3-keto-5-aminohexanoate + acetyl-CoA = L-3-aminobutyryl-CoA + acetoacetate."^^xsd:string) AnnotationAssertion( "3-keto-5-aminohexanoate cleavage enzyme"^^xsd:string) AnnotationAssertion(rdfs:label "3-keto-5-aminohexanoate cleavage activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "gamma-hydroxybutyryl-CoA dehydratase activity"^^xsd:string) AnnotationAssertion( "4-hydroxybutanoyl-CoA hydro-lyase"^^xsd:string) AnnotationAssertion( "4-hydroxybutyryl-CoA dehydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxybutanoyl-CoA dehydratase activity"^^xsd:string) AnnotationAssertion( "gamma-hydroxybutanoyl-CoA dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.120"^^xsd:string) "Catalysis of the reaction: 4-hydroxybutanoyl-CoA = vinylacetyl-CoA + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.83"^^xsd:string) Annotation( "RHEA:22735"^^xsd:string) "Catalysis of the reaction: (4-hydroxyphenyl)acetate + H(+) = 4-cresol + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.83"^^xsd:string) "p-hydroxyphenylacetate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.83"^^xsd:string) "4-Hpd activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxyphenylacetate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.83"^^xsd:string) "4-hydroxyphenylacetate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.83"^^xsd:string) "p-Hpd activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.83"^^xsd:string) "4-(hydroxyphenyl)acetate carboxy-lyase (4-methylphenol-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:YOL066C-MONOMER"^^xsd:string) "2,5-diamino-6-(5-phosphoribitylamino)pyrimidin-4(3H)-one deaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10058"^^xsd:string) Annotation( "PMID:11889103"^^xsd:string) "Catalysis of the reaction: 2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + H2O = 5-amino-6-(5-phospho-D-ribosylamino)uracil + ammonia."^^xsd:string) AnnotationAssertion( "DRAP deaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12824170"^^xsd:string) "Catalysis of the reaction: 2-keto-3-deoxygalactonate = D-glyceraldehyde + pyruvate."^^xsd:string) AnnotationAssertion(rdfs:label "2-keto-3-deoxygalactonate aldolase activity"^^xsd:string) AnnotationAssertion( "KDGal aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12824170"^^xsd:string) "Catalysis of the reaction: 2-keto-3-deoxygluconate = D-glyceraldehyde + pyruvate."^^xsd:string) AnnotationAssertion( "KDG aldolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-keto-3-deoxygluconate aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "pyrimidine phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:01282"^^xsd:string) "Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)-2,4(1H,3H)-pyrimidinedione + H2O = 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione + orthophosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:01835"^^xsd:string) "Catalysis of the reaction: 5-aminoimidazole + CO2 = 5-amino-4-imidazole carboxylate."^^xsd:string) AnnotationAssertion(rdfs:label "5-amino-4-imidazole carboxylate lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-keto-4-methylthiobutyrate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:01683"^^xsd:string) "Catalysis of the reaction: 2-keto-4-methylthiobutyrate + L-glutamine = 2-oxoglutaramate + L-methionine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:01536"^^xsd:string) "Catalysis of the reaction: 2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one + H2O = 2,5-diamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one + formate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:02121"^^xsd:string) "Catalysis of the reaction: 5-ureido-4-imidazole carboxylate + H2O = 5-amino-4-imidazole carboxylate + NH3 + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "5-ureido-4-imidazole carboxylate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "6-hydroxynicotinate 3-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:10091591"^^xsd:string) "Catalysis of the oxidative decarboxylation of 6-hydroxynicotinate to 2,5-dihydroxypyridine, dependent on O2, NADH +H+ and FAD."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "6-hydroxynicotinate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.3"^^xsd:string) "6-hydroxynicotinic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.3"^^xsd:string) "6-hydroxynicotinate hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.3"^^xsd:string) Annotation( "RHEA:22811"^^xsd:string) "Catalysis of the reaction: 6-hydroxynicotinate + H(2)O + O(2) = 2,6-dihydroxynicotinate + H(2)O(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.3"^^xsd:string) "6-hydroxynicotinic acid hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.3"^^xsd:string) "6-hydroxynicotinate:O2 oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA-3-methylbase glycosylase activity"^^xsd:string) AnnotationAssertion( "MagIII"^^xsd:string) AnnotationAssertion( "DNA-3-methyladenine glycosylase III"^^xsd:string) AnnotationAssertion(Annotation( "IMG:00576"^^xsd:string) Annotation( "PMID:10777493"^^xsd:string) Annotation( "PMID:14517230"^^xsd:string) "Catalysis of the reaction: DNA containing 3-methylbase + H2O = DNA with abasic site + 3-methylbase. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylpurine or 3-methylpyrimidine base and the deoxyribose sugar to remove the methylated base, leaving an apurinic or apyrimidinic site."^^xsd:string) AnnotationAssertion( "Mag III"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA-N1-methyladenine dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:00579"^^xsd:string) Annotation( "PMID:19786499"^^xsd:string) "Catalysis of the oxidative demethylation of N1-methyladenine and N3-methylcytosine in DNA and RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenine and N3-methylcytosine as formaldehyde."^^xsd:string) AnnotationAssertion( "alpha-ketoglutarate-dependent dioxygenase"^^xsd:string) AnnotationAssertion( "AlkB"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.21.7"^^xsd:string) "DNase V activity"^^xsd:string) AnnotationAssertion( "endodeoxyribonuclease V"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.7"^^xsd:string) "Escherichia coli endodeoxyribonuclease V activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.7"^^xsd:string) "Catalysis of the endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.21.7"^^xsd:string) "endonuclease V activity"^^xsd:string) AnnotationAssertion(rdfs:label "deoxyribonuclease V activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "reduced coenzyme F420 dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15823"^^xsd:string) "1,5-dihydrocoenzyme F420 dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8106"^^xsd:string) "Catalysis of the reaction: methanophenazine + reduced coenzyme F420 = dihydromethanophenazine + coenzyme F420."^^xsd:string) AnnotationAssertion( "F420H2 dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "MUG"^^xsd:string) AnnotationAssertion(rdfs:label "G/U mismatch-specific uracil-DNA glycosylase activity"^^xsd:string) AnnotationAssertion( "uracil mismatch repair protein"^^xsd:string) AnnotationAssertion( "GU mismatch-specific uracil-DNA glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:00570"^^xsd:string) Annotation( "SP:O59825"^^xsd:string) "Catalysis of the removal of uracil from a U*G mispair by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free uracil and leaves an apyrimidinic (AP) site."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.29"^^xsd:string) Annotation( "RHEA:22471"^^xsd:string) "Catalysis of the reaction: GTP + 3 H(2)O = 2-amino-5-formylamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + 3 H(+) + 2 phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.29"^^xsd:string) "GTP cyclohydrolase III activity"^^xsd:string) AnnotationAssertion(rdfs:label "GTP cyclohydrolase IIa activity"^^xsd:string) AnnotationAssertion( "GTP 8,9-hydrolase (phosphate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.29"^^xsd:string) "GTP 8,9-dihydrolase (phosphate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-2-aminoadipate N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01447"^^xsd:string) "Catalysis of the reaction: L-2-aminoadipate + acetyl-CoA = N2-acetyl-L-aminoadipate + CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "LPPG:FO 2-phospho-L-lactate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01551"^^xsd:string) "Catalysis of the reaction: 7,8-didemethyl-8-hydroxy-5-deazariboflavin + lactyl-2-diphospho-5'-guanosine = coenzyme F420-0 + GMP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "N-acetyl-L-aminoadipate 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N2-acetyl-L-aminoadipate kinase activity"^^xsd:string) AnnotationAssertion( "acetylaminoadipate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01448"^^xsd:string) "Catalysis of the reaction: ATP + N-acetyl-L-aminoadipate = ADP + N-acetyl-L-aminoadipate 5-phosphate."^^xsd:string) AnnotationAssertion( "N-acetylaminoadipate kinase activity"^^xsd:string) AnnotationAssertion( "LysZ"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N2-acetyl-L-aminoadipate semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01449"^^xsd:string) "Catalysis of the reaction: N2-acetyl-L-aminoadipyl-delta-phosphate + NADPH + H+ = N2-acetyl-L-aminoadipate semialdehyde + NADP+ + orthophosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:01450"^^xsd:string) "Catalysis of the reaction: N2-acetyl-L-aminoadipate semialdehyde + L-glutamate = 2-oxoglutarate + N2-acetyl-L-lysine."^^xsd:string) AnnotationAssertion(rdfs:label "N2-acetyl-L-lysine aminotransferase activity"^^xsd:string) AnnotationAssertion( "N-acetyl-lysine aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:01451"^^xsd:string) "Catalysis of the reaction: N2-acetyl-L-lysine + H2O = acetate + L-lysine."^^xsd:string) AnnotationAssertion(rdfs:label "N2-acetyl-L-lysine deacetylase activity"^^xsd:string) AnnotationAssertion( "N-acetyl-lysine deacetylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "O-succinylbenzoate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01733"^^xsd:string) "Catalysis of the reaction: 2-succinylbenzoate + H2O = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phenol:water dikinase activity"^^xsd:string) AnnotationAssertion( "ATP:phenol:water phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15547277"^^xsd:string) "Catalysis of the reaction: phenol + MgATP + H2O = phenylphosphate + MgAMP + orthophosphate."^^xsd:string) AnnotationAssertion( "phenylphosphate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phenol, water dikinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.57"^^xsd:string) "Catalysis of the transfer of one or more alpha-D-mannose residues from GDP-mannose to positions 2,6 and others in 1-phosphatidyl-myo-inositol."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.57"^^xsd:string) "guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.57"^^xsd:string) "GDPmannose:1-phosphatidyl-myo-inositol alpha-D-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.57"^^xsd:string) "phosphatidyl-myo-inositol alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.57"^^xsd:string) "GDP-mannose:1-phosphatidyl-1D-myo-inositol alpha-D-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.57"^^xsd:string) "GDP mannose-phosphatidyl-myo-inositol alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.57"^^xsd:string) "GDP mannose:1-phosphatidyl-myo-inositol alpha-D-mannosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "polyphosphate:AMP phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11237733"^^xsd:string) "Catalysis of the reaction: (polyphosphate)n + AMP = (polyphosphate)n-1 + ADP."^^xsd:string) AnnotationAssertion( "PPT"^^xsd:string) AnnotationAssertion( "PAP"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "adenosylcobinamide kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.156"^^xsd:string) "Catalysis of the reaction: RTP + adenosylcobinamide = adenosylcobinamide phosphate + RDP (where RTP is either ATP or GTP)."^^xsd:string) AnnotationAssertion( "AdoCbi kinase/AdoCbi-phosphate guanylyltransferase"^^xsd:string) AnnotationAssertion( "adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase"^^xsd:string) AnnotationAssertion( "RTP:adenosylcobinamide phosphotransferase activity"^^xsd:string) AnnotationAssertion( "CobU"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.168"^^xsd:string) "dihydrolipoyl transacylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.168"^^xsd:string) "2-methylpropanoyl-CoA:enzyme-6-N-(dihydrolipoyl)lysine:S-(2-methylpropanoyl)transferase activity"^^xsd:string) AnnotationAssertion( "enzyme-dihydrolipoyllysine:2-methylpropanoyl-CoA S-(2-methylpropanoyl)transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.168"^^xsd:string) "2-methylpropanoyl-CoA:enzyme-N6-(dihydrolipoyl)lysine:S-(2-methylpropanoyl)transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.168"^^xsd:string) "Catalysis of the reaction: 2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "alpha-ribazole-5'-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion( "CobC"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.73"^^xsd:string) Annotation( "RHEA:24459"^^xsd:string) "Catalysis of the reaction: alpha-ribazole 5'-phosphate + H(2)O = alpha-ribazole + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-ribazole phosphatase activity"^^xsd:string) AnnotationAssertion( "alpha-ribazole-5'-P phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.90"^^xsd:string) Annotation( "RHEA:23507"^^xsd:string) "Catalysis of the reaction: adenosylcobinamide + H(2)O = (R)-1-aminopropan-2-ol + adenosylcobyrate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.90"^^xsd:string) "adenosylcobinamide amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.90"^^xsd:string) "AdoCbi hydrolase activity"^^xsd:string) AnnotationAssertion( "CbiZ"^^xsd:string) AnnotationAssertion(rdfs:label "adenosylcobinamide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.90"^^xsd:string) "AdoCbi amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "adenosylcobinamide-phosphate synthase activity"^^xsd:string) AnnotationAssertion( "adenosylcobyric acid:(R)-1-aminopropan-2-yl phosphate ligase (ADP-forming)"^^xsd:string) AnnotationAssertion( "CbiB"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.10"^^xsd:string) "AdoCbi-P synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.10"^^xsd:string) "Catalysis of the reactions: ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate, and ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol = ADP + phosphate + adenosylcobinamide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.13"^^xsd:string) "acetate thiokinase activity"^^xsd:string) AnnotationAssertion( "acetyl coenzyme A synthetase (adenosine diphosphate-forming)"^^xsd:string) AnnotationAssertion( "acetate--CoA ligase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.13"^^xsd:string) "Catalysis of the reaction: ATP + acetate + CoA = ADP + phosphate + acetyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.13"^^xsd:string) "acetate:CoA ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "acetate-CoA ligase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.13"^^xsd:string) "acetyl-CoA synthetase (ADP-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "branched chain acyl-CoA synthetase (ADP-forming) activity"^^xsd:string) AnnotationAssertion( "branched chain acyl CoA synthetase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "branched-chain acyl-CoA synthetase (ADP-forming) activity"^^xsd:string) AnnotationAssertion( "branched-chain acyl CoA synthetase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01425"^^xsd:string) "Catalysis of the reaction: ATP + 2-methylbutanoate + CoA = ADP + orthophosphate + 2-methylbutanoyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acetyldiaminopimelate aminotransferase activity"^^xsd:string) AnnotationAssertion( "N-acetyl-diaminopimelate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:00444"^^xsd:string) Annotation( "PMID:1906065"^^xsd:string) "Catalysis of the reaction: N-acetyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-acetyl-2-L-amino-6-oxoheptanedioate + L-glutamate."^^xsd:string) AnnotationAssertion( "N-acetyl-L,L-diaminopimelate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "CDP-2,3-di-O-geranylgeranyl-sn-glycerol:l-serine O-archaetidyltransferase activity"^^xsd:string) AnnotationAssertion( "CDP-2,3-di-O-geranylgeranyl-sn-glycerol inositol 1-archaetidyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "archaetidylserine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01567"^^xsd:string) Annotation( "PMID:12562787"^^xsd:string) "Catalysis of the reaction: CDP-digeranylgeranylglycerol + L-serine = archaetidylserine + CMP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:01427"^^xsd:string) "Catalysis of the reaction: ATP + phenylacetate + CoA = ADP + orthophosphate + phenylacetyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "aryl-CoA synthetase (ADP-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UTP:glucose-1-phosphate uridylyltransferase regulator activity"^^xsd:string) AnnotationAssertion( "glucose-1-phosphate uridylyltransferase regulator activity"^^xsd:string) AnnotationAssertion( "UDP-glucose diphosphorylase regulator activity"^^xsd:string) AnnotationAssertion( "UDP-glucose pyrophosphorylase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Modulates the activity of UTP:glucose-1-phosphate uridylyltransferase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:00545"^^xsd:string) Annotation( "InterPro:IPR007691"^^xsd:string) "Catalysis of the reaction: UDP-3-O-(3-hydroxytetradecanoyl)glucosamine + (R)-3-hydroxytetradecanoyl-[acyl-carrier protein] = UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + [acyl-carrier protein]."^^xsd:string) AnnotationAssertion(rdfs:label "UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "DNA mismatch endonuclease"^^xsd:string) AnnotationAssertion( "Vsr mismatch endonuclease"^^xsd:string) AnnotationAssertion(rdfs:label "T/G mismatch-specific endonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:00606"^^xsd:string) Annotation( "SP:P09184"^^xsd:string) "Catalysis of the repair of T/G mismatches arising from deamination of 5-methylcytosine in DNA by nicking double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the mismatched thymidine residue. The incision is mismatch-dependent and strand-specific, in favor of the G-containing strand. The incision serves as a starting point for subsequent excision repair by DNA polymerase I, which excises thymidine and reinserts cytidine."^^xsd:string) AnnotationAssertion( "V.EcoKDcm"^^xsd:string) AnnotationAssertion( "very short patch repair protein"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.73"^^xsd:string) Annotation( "IMG:00235"^^xsd:string) Annotation( "PMID:15790858"^^xsd:string) Annotation( "PMID:16380427"^^xsd:string) Annotation( "PMID:17110438"^^xsd:string) "Catalysis of the reaction: O-phospho-L-seryl-tRNACys + sulfide = L-cysteinyl-tRNACys + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "Sep-tRNA:Cys-tRNA synthase activity"^^xsd:string) AnnotationAssertion( "Sep-tRNA:Cys-tRNA synthetase activity"^^xsd:string) AnnotationAssertion( "SepCysS"^^xsd:string) AnnotationAssertion( "O-phosphoseryl-tRNA:cysteinyl-tRNA synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Pyrrolysine-tRNA ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyrrolysyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:02553"^^xsd:string) Annotation( "PMID:15314242"^^xsd:string) Annotation( "SP:Q8TUB8"^^xsd:string) "Catalysis of the reaction: ATP + L-pyrrolysine + tRNA(Pyl) = AMP + diphosphate + L-pyrrolysyl-tRNA(Pyl)."^^xsd:string) AnnotationAssertion( "PylRS"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.21"^^xsd:string) "S-(5-deoxy-D-ribos-5-yl)-L-homocysteine homocysteine-lyase [(4S)-4,5-dihydroxypentan-2,3-dione-forming]"^^xsd:string) AnnotationAssertion( "ribosylhomocysteinase activity"^^xsd:string) AnnotationAssertion( "3.2.1.148"^^xsd:string) AnnotationAssertion( "LuxS"^^xsd:string) AnnotationAssertion( "S-ribosylhomocysteinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.21"^^xsd:string) Annotation( "RHEA:17756"^^xsd:string) "Catalysis of the reaction: S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3-dione + L-homocysteine."^^xsd:string) AnnotationAssertion(rdfs:label "S-ribosylhomocysteine lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "demethylmenaquinone methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01848"^^xsd:string) "Catalysis of the reaction: 2-demethylmenaquinone + S-adenosyl-L-methionine = menaquinone + S-adenosyl-L-homocysteine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:01870"^^xsd:string) "Catalysis of the reaction: ATP + cytidine = ADP + CMP."^^xsd:string) AnnotationAssertion(rdfs:label "cytidine kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "acylphosphate:glycerol-3-phosphate acyltransferase activity"^^xsd:string) AnnotationAssertion( "acylphosphate glycerol-3-phosphate acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01872"^^xsd:string) Annotation( "PMID:17308305"^^xsd:string) "Catalysis of the reaction: acyl phosphate + sn-glycerol 3-phosphate = 1-acyl-sn-glycerol 3-phosphate + orthophosphate."^^xsd:string) AnnotationAssertion( "acyl-phosphate:glycerol-3-phosphate acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acyl-phosphate glycerol-3-phosphate acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "coenzyme F420-0 gamma-glutamyl ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01552"^^xsd:string) Annotation( "PMID:17669425"^^xsd:string) "Catalysis of the reactions: (1) GTP + F420-0 + L-glutamate = GDP + phosphate + F420-1, and (2) GTP + F420-1 + L-glutamate = GDP + phosphate + gamma-F420-2. This is the GTP-dependent successive addition of two L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form F420-0-glutamyl-glutamate (F420-2), with a gamma-linkage between the two glutamates."^^xsd:string) AnnotationAssertion( "F420-0 gamma-glutamyl ligase activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "F420-2 alpha-glutamyl ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01553"^^xsd:string) "Catalysis of the reaction: coenzyme F420-2 + L-glutamate + GTP = coenzyme F420-3 + GDP + orthophosphate."^^xsd:string) AnnotationAssertion(rdfs:label "coenzyme F420-2 alpha-glutamyl ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cobyrinate a c-diamide synthase activity"^^xsd:string) AnnotationAssertion( "cobyrinate a c diamide synthase activity"^^xsd:string) AnnotationAssertion( "cobyrinate a,c diamide synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cobyrinate a,c-diamide synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01814"^^xsd:string) "Catalysis of the reaction: cobyrinate + 2 L-glutamine + 2 ATP + 2 H2O = cob(II)yrinate a,c-diamide + 2 L-glutamate + 2 ADP + 2 orthophosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "precorrin-6Y methylase"^^xsd:string) AnnotationAssertion(Annotation( "IMG:02115"^^xsd:string) Annotation( "MetaCyc:RXN-8766"^^xsd:string) "Catalysis of the reaction: S-adenosylmethionine + cobalt-precorrin 6B = S-adenosylhomocysteine + cobalt-precorrin 7."^^xsd:string) AnnotationAssertion( "precorrin-6Y C5,15-methyltransferase (decarboxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "cobalt-precorrin-6B C5-methyltransferase activity"^^xsd:string) AnnotationAssertion( "cobalt-precorrin 6B C5-methyltransferase activity"^^xsd:string) AnnotationAssertion( "precorrin-6 methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cobalt-precorrin 7 C15-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:02116"^^xsd:string) Annotation( "MetaCyc:RXN-8767"^^xsd:string) "Catalysis of the reaction: cobalt-precorrin 7 + S-adenosyl-L-methionine = cobalt-precorrin 8 + S-adenosyl-L-homocysteine + CO2."^^xsd:string) AnnotationAssertion( "precorrin-6Y C5,15-methyltransferase (decarboxylating)"^^xsd:string) AnnotationAssertion( "precorrin-6 methyltransferase"^^xsd:string) AnnotationAssertion( "precorrin-6Y methylase"^^xsd:string) AnnotationAssertion(rdfs:label "cobalt-precorrin-7 C15-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cobalt-precorrin-8X methylmutase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cobalt-precorrin-8 methylmutase activity"^^xsd:string) AnnotationAssertion( "cobalt-precorrin 8 methylmutase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:02117"^^xsd:string) Annotation( "MetaCyc:RXN-8768"^^xsd:string) "Catalysis of the reaction: cobalt-precorrin 8 = cobyrinate."^^xsd:string) AnnotationAssertion( "cobalt-precorrin 8X methylmutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cobalt-precorrin-5A acetaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:02112"^^xsd:string) Annotation( "MetaCyc:RXN-8763"^^xsd:string) "Catalysis of the reaction: cobalt-precorrin 5A + H2O = cobalt-precorrin 5B + acetaldehyde."^^xsd:string) AnnotationAssertion( "cobalt-precorrin 5A acetaldehyde-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:02112"^^xsd:string) Annotation( "MetaCyc:RXN-8764"^^xsd:string) "Catalysis of the reaction: cobalt-precorrin 5B + S-adenosylmethionine = S-adenosylhomocysteine + cobalt-precorrin 6A."^^xsd:string) AnnotationAssertion(rdfs:label "cobalt-precorrin-5B C1-methyltransferase activity"^^xsd:string) AnnotationAssertion( "cobalt-precorrin 5B C1-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.151"^^xsd:string) Annotation( "IMG:01812"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + cobalt-factor II = S-adenosyl-L-homocysteine + cobalt-factor III."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.151"^^xsd:string) "cobalt-precorrin-2 C(20)-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cobalt-factor II C20-methyltransferase activity"^^xsd:string) AnnotationAssertion( "CbiL"^^xsd:string) AnnotationAssertion( "cobalt-factor II C20 methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.151"^^xsd:string) "S-adenosyl-L-methionine:cobalt-factor-II C20-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cobalt-precorrin 3 C17-methyltransferase activity"^^xsd:string) AnnotationAssertion( "cobalt-precorrin-3 methylase"^^xsd:string) AnnotationAssertion(rdfs:label "cobalt-precorrin-3 C17-methyltransferase activity"^^xsd:string) AnnotationAssertion( "cobalt-precorrin-3B C17-methyltransferase activity"^^xsd:string) AnnotationAssertion( "cobalt-precorrin-3 methyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "IMG:02110"^^xsd:string) Annotation( "MetaCyc:RXN-8761"^^xsd:string) "Catalysis of the reaction: cobalt-precorrin 3 + S-adenosyl-L-methionine = cobalt-precorrin 4 + S-adenosyl-L-homocysteine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, oxidizing metal ions with flavin as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.8"^^xsd:string) "Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and flavin acts as an electron acceptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cob(II)yrinic acid a,c-diamide reductase activity"^^xsd:string) AnnotationAssertion( "cob(II)yrinic acid-a,c-diamide:FMN oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.8.1"^^xsd:string) Annotation( "RHEA:24303"^^xsd:string) "Catalysis of the reaction: 2 cob(I)yrinate a,c diamide + FMN + 3 H(+) = 2 cob(II)yrinate a,c diamide + FMNH(2)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.3.17"^^xsd:string) Annotation( "RHEA:15604"^^xsd:string) "Catalysis of the reaction: (R)-3-phenyllactate + [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonatooxy)oxolan-2-yl]methyl {[(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-{[(2E)-3-phenylprop-2-enoyl]sulfanyl}ethyl)carbamoyl]ethyl}carbamoyl)propyl phosphonato]oxy}phosphonate = (R)-3-phenyllactoyl-CoA + trans-cinnamate."^^xsd:string) AnnotationAssertion(rdfs:label "cinnamoyl-CoA:phenyllactate CoA-transferase activity"^^xsd:string) AnnotationAssertion( "FldA"^^xsd:string) AnnotationAssertion( "(E)-cinnamoyl-CoA:(R)-phenyllactate CoA-transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cinnamate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.-"^^xsd:string) Annotation( "IMG:01615"^^xsd:string) Annotation( "PMID:10849007"^^xsd:string) "Catalysis of the reaction: 3-phenylpropanoate + NAD+ = (E)-cinnamate + NADH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "dimethylamine:corrinoid methyltransferase activity"^^xsd:string) AnnotationAssertion( "DMAMT 1"^^xsd:string) AnnotationAssertion( "DMA methyltransferase 1"^^xsd:string) AnnotationAssertion(rdfs:label "dimethylamine methyltransferase activity"^^xsd:string) AnnotationAssertion( "MT1"^^xsd:string) AnnotationAssertion( "mtbB1"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01321"^^xsd:string) Annotation( "MetaCyc:RXN-8100"^^xsd:string) Annotation( "PMID:9874228"^^xsd:string) "Catalysis of the reaction: dimethylamine + a dimethylamine corrinoid protein = a methylated dimethylamine corrinoid protein + methylamine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.2.18"^^xsd:string) Annotation( "RHEA:17212"^^xsd:string) "Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + 2 H(2)O = 2-formylglutarate + NH(4)(+)."^^xsd:string) AnnotationAssertion( "6-oxo-1,4,5,6-tetrahydronicotinate amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "enamidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-ribofuranosylaminobenzene 5'-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:01544"^^xsd:string) Annotation( "PMID:12142414"^^xsd:string) "Catalysis of the reaction: 4-aminobenzoate + 5-phospho-alpha-D-ribose 1-diphosphate = 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + CO2 + diphosphate."^^xsd:string) AnnotationAssertion( "beta-RFAP synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:01432"^^xsd:string) Annotation( "PMID:3801411"^^xsd:string) "Catalysis of the reaction: formate + coenzyme F420 = CO2 + reduced coenzyme F420."^^xsd:string) AnnotationAssertion(rdfs:label "formate dehydrogenase (coenzyme F420) activity"^^xsd:string) AnnotationAssertion( "formate dehydrogenase (F420) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:01506"^^xsd:string) "Catalysis of the reaction: D-glyceraldehyde + H2O + acceptor = D-glycerate + reduced acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "glyceraldehyde oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glyceraldehyde dehydrogenase (NADP) activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01555"^^xsd:string) "Catalysis of the reaction: D-glyceraldehyde + H2O + NADP+ = D-glycerate + NADPH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "GAPOR"^^xsd:string) AnnotationAssertion(rdfs:label "glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.6"^^xsd:string) "glyceraldehyde-3-phosphate ferredoxin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.6"^^xsd:string) "Catalysis of the reaction: D-glyceraldehyde-3-phosphate + H2O + 2 oxidized ferredoxin = 3-phospho-D-glycerate + 2 H+ + 2 reduced ferredoxin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.6"^^xsd:string) "glyceraldehyde-3-phosphate Fd oxidoreductase activity"^^xsd:string) AnnotationAssertion( "D-glyceraldehyde-3-phosphate:ferredoxin oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:01510"^^xsd:string) Annotation( "MetaCyc:GKI-RXN"^^xsd:string) Annotation( "PMID:14413719"^^xsd:string) "Catalysis of the reaction: D-glycerate + ATP = 2-phospho-D-glycerate + ADP."^^xsd:string) AnnotationAssertion(rdfs:label "glycerate 2-kinase activity"^^xsd:string) AnnotationAssertion( "glycerate kinase"^^xsd:string) AnnotationAssertion( "D-glycerate 2-kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.3.19"^^xsd:string) "Catalysis of the reactions: (1) glycine + H2O + O2 = glyoxylate + NH3 + hydrogen peroxide; (2) D-alanine + H2O + O2 = pyruvate + NH3 + hydrogen peroxide; (3) sarcosine + H2O + O2 = glyoxylate + methylamine + hydrogen peroxide; (4) N-ethylglycine + H2O + O2 = glyoxylate + ethylamine + hydrogen peroxide."^^xsd:string) AnnotationAssertion( "glycine:oxygen oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(rdfs:label "glycine oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hexulose-6-phosphate isomerase activity"^^xsd:string) AnnotationAssertion( "HUMPI"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01502"^^xsd:string) Annotation( "MetaCyc:R12-RXN"^^xsd:string) Annotation( "PMID:11839305"^^xsd:string) "Catalysis of the reaction: D-arabino-3-hexulose 6-phosphate = D-fructose 6-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hexulose-6-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01503"^^xsd:string) Annotation( "PMID:16075199"^^xsd:string) "Catalysis of the reaction: D-ribulose 5-phosphate + formaldehyde = D-arabino-3-hexulose 6-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.5.9"^^xsd:string) Annotation( "RHEA:12547"^^xsd:string) "Catalysis of the reaction: 2 L-glutamine + 2 ATP + 2 H(2)O + hydrogenobyrinate = 2 L-glutamate + 2 ADP + 4 H(+) + hydrogenobyrinate a,c-diamide + 2 phosphate."^^xsd:string) AnnotationAssertion( "hydrogenobyrinic-acid:L-glutamine amido-ligase (AMP-forming)"^^xsd:string) AnnotationAssertion( "hydrogenobyrinic acid a,c diamide synthase (glutamine-hydrolysing) activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) activity"^^xsd:string) AnnotationAssertion( "CobB"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:01759"^^xsd:string) "Catalysis of the reaction: demethylspheroidene + S-adenosyl-L-methionine = spheroidene + S-adenosyl-L-homocysteine."^^xsd:string) AnnotationAssertion(rdfs:label "hydroxyneurosporene-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "imidazolone hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:02122"^^xsd:string) "Catalysis of the reaction: N-formiminoglycine = imidazolone + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "indolepyruvate ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.8"^^xsd:string) "Catalysis of the reaction: (indol-3-yl)pyruvate + CoA + oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.8"^^xsd:string) "3-(indol-3-yl)pyruvate:ferredoxin oxidoreductase (decarboxylating, CoA-indole-acetylating)"^^xsd:string) AnnotationAssertion( "IOR"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.8"^^xsd:string) "indolepyruvate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.8"^^xsd:string) "3-(indol-3-yl)pyruvate synthase (ferredoxin) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "keto-acid formate acetyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "IMG:00725"^^xsd:string) Annotation( "MetaCyc:KETOBUTFORMLY-RXN"^^xsd:string) "Catalysis of the reaction: 2-oxobutanoate + CoA = propionyl-CoA + formate."^^xsd:string) AnnotationAssertion( "keto-acid formate-lyase activity"^^xsd:string) AnnotationAssertion( "keto-acid formate lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "keto acid formate lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.7.7"^^xsd:string) "keto-valine-ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.7"^^xsd:string) "branched-chain oxo acid ferredoxin reductase activity"^^xsd:string) AnnotationAssertion( "3-methyl-2-oxobutanoate:ferredoxin oxidoreductase (decarboxylating; CoA-2-methylpropanoylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.7"^^xsd:string) "branched-chain ketoacid ferredoxin reductase activity"^^xsd:string) AnnotationAssertion( "VOR"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.7"^^xsd:string) "ketoisovalerate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.7"^^xsd:string) "3-methyl-2-oxobutanoate synthase (ferredoxin) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.7"^^xsd:string) "2-ketoisovalerate ferredoxin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.7"^^xsd:string) "2-oxoisovalerate ferredoxin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.7"^^xsd:string) "ketoisovalerate ferredoxin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.7"^^xsd:string) "Catalysis of the reaction: 3-methyl-2-oxobutanoate + CoA + oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + reduced ferredoxin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lyso-ornithine lipid acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:02097"^^xsd:string) Annotation( "PMID:15341653"^^xsd:string) "Catalysis of the reaction: lyso-ornithine lipid + acyl-[acyl-carrier protein] = ornithine lipid + [acyl-carrier protein]."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ornithine-acyl[acyl carrier protein] N-acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ornithine-acyl [acyl carrier protein] N-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:02096"^^xsd:string) "Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + L-ornithine = lyso-ornithine lipid + [acyl-carrier protein]."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphate:acyl-[acyl carrier protein] acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01871"^^xsd:string) "Catalysis of the reaction: acyl-[acyl-carrier protein] + orthophosphate = acyl phosphate + [acyl-carrier protein]."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phosphatidylinositol 4-phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol-4-phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01360"^^xsd:string) "Catalysis of the reaction: phosphatidylinositol-4-phosphate + H2O = phosphatidylinositol + orthophosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phosphatidylinositol 3,5-bisphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01359"^^xsd:string) Annotation( "PMID:10806194"^^xsd:string) Annotation( "PMID:16607019"^^xsd:string) "Catalysis of the reaction: phosphatidylinositol-3,5-bisphosphate + H2O = phosphatidylinositol-3-phosphate + orthophosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phospholactate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01547"^^xsd:string) "Catalysis of the reaction: 2-phospho-(S)-lactate + GTP = lactyl-2-diphospho-5'-guanosine + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "formate-dependent GAR transformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01297"^^xsd:string) Annotation( "PMID:8117714"^^xsd:string) "Catalysis of the reaction: formate + ATP + 5'-phospho-ribosylglycinamide = 5'-phosphoribosyl-N-formylglycinamide + ADP + diphosphate."^^xsd:string) AnnotationAssertion( "GART 2"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoribosylglycinamide formyltransferase 2 activity"^^xsd:string) AnnotationAssertion( "GAR transformylase 2"^^xsd:string) AnnotationAssertion( "5'-phosphoribosylglycinamide transformylase 2"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:00622"^^xsd:string) Annotation( "PMID:17110438"^^xsd:string) "Catalysis of the reaction: tRNA(Cys) + O-phospho-L-serine + ATP = AMP + diphosphate + phosphoseryl-tRNA(Cys)."^^xsd:string) AnnotationAssertion( "SepRS"^^xsd:string) AnnotationAssertion( "phosphoserine--tRNA(Cys) ligase activity"^^xsd:string) AnnotationAssertion( "phosphoserine-tRNACys ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoserine-tRNA(Cys) ligase activity"^^xsd:string) AnnotationAssertion( "O-phosphoseryl-tRNA(Cys) synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.19"^^xsd:string) "PSL synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.19"^^xsd:string) "(2R)-O-phospho-3-sulfolactate sulfo-lyase (phosphoenolpyruvate-forming)"^^xsd:string) AnnotationAssertion( "(2R)-O-phospho-3-sulfolactate sulfo-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphosulfolactate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.19"^^xsd:string) Annotation( "RHEA:22787"^^xsd:string) "Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate = phosphoenolpyruvate + sulfite."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.19"^^xsd:string) "(2R)-phospho-3-sulfolactate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "CobG"^^xsd:string) AnnotationAssertion(rdfs:label "precorrin-3B synthase activity"^^xsd:string) AnnotationAssertion( "precorrin-3A,NADH:oxygen oxidoreductase (20-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.83"^^xsd:string) "precorrin-3X synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.83"^^xsd:string) Annotation( "RHEA:17296"^^xsd:string) "Catalysis of the reaction: H(+) + NADH + O(2) + precorrin-3A = H(2)O + NAD(+) + precorrin-3B."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.152"^^xsd:string) "precorrin-6X synthase (deacetylating) activity"^^xsd:string) AnnotationAssertion( "CobF"^^xsd:string) AnnotationAssertion( "S-adenosyl-L-methionine:precorrin-5 C1-methyltransferase (deacetylating)"^^xsd:string) AnnotationAssertion(rdfs:label "precorrin-6A synthase (deacetylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.152"^^xsd:string) Annotation( "RHEA:18264"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + H(2)O + precorrin-5 = S-adenosyl-L-homocysteine + acetate + 2 H(+) + precorrin-6X."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12603323"^^xsd:string) "Catalysis of the irreversible NADH-dependent formation of propionyl-CoA from acryloyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "propionyl-CoA dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:01589"^^xsd:string) Annotation( "MetaCyc:RXN0-268"^^xsd:string) "Catalysis of the reaction: succinate + propionyl-CoA = succinyl-CoA + propionate."^^xsd:string) AnnotationAssertion( "propionyl-CoA:succinate CoA transferase activity"^^xsd:string) AnnotationAssertion( "propionyl-CoA succinate CoA-transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "propionyl-CoA:succinate CoA-transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "5S ribosomal RNA maturation endonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.8"^^xsd:string) "5S ribosomal maturation nuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.8"^^xsd:string) "RNase M5 activity"^^xsd:string) AnnotationAssertion(rdfs:label "ribonuclease M5 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.26.8"^^xsd:string) Annotation( "IMG:02522"^^xsd:string) "Catalysis of the endonucleolytic cleavage of RNA, removing 21 and 42 nucleotides, respectively, from the 5'- and 3'-termini of a 5S-rRNA precursor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:01761"^^xsd:string) Annotation( "MetaCyc:RXN-10670"^^xsd:string) Annotation( "PMID:16086104"^^xsd:string) Annotation( "PMID:16158287"^^xsd:string) "Catalysis of the reaction: spheroidene + O2 = spheroidenone + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "spheroidene monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.71"^^xsd:string) "N-succinyl-L-glutamate 5-semialdehyde:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion( "succinyl glutamate-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion( "AstD"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.71"^^xsd:string) Annotation( "RHEA:10815"^^xsd:string) "Catalysis of the reaction: N-succinyl-L-glutamate 5-semialdehyde + H(2)O + NAD(+) = N-succinyl-L-glutamate + 2 H(+) + NADH."^^xsd:string) AnnotationAssertion( "AruD"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.71"^^xsd:string) "succinylglutamic semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion( "SGSD"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.71"^^xsd:string) "N-succinylglutamate 5-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "succinylglutamate-semialdehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "succinyl ornithine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.81"^^xsd:string) Annotation( "RHEA:16956"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + N(2)-succinyl-L-ornithine = N-succinyl-L-glutamate 5-semialdehyde + L-glutamate."^^xsd:string) AnnotationAssertion( "N2-succinylornithine 5-aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.81"^^xsd:string) "succinylornithine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.81"^^xsd:string) "succinyl-ornithine transaminase activity"^^xsd:string) AnnotationAssertion( "AstC"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.81"^^xsd:string) "N(2)-succinylornithine 5-aminotransferase activity"^^xsd:string) AnnotationAssertion( "N2-succinyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"^^xsd:string) AnnotationAssertion( "SOAT"^^xsd:string) AnnotationAssertion(rdfs:label "succinylornithine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.81"^^xsd:string) "2-N-succinyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "SOR"^^xsd:string) AnnotationAssertion( "sulphur oxygenase reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfur oxygenase reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:00713"^^xsd:string) Annotation( "MetaCyc:RXN-8226"^^xsd:string) Annotation( "PMID:1522063"^^xsd:string) "Catalysis of the reaction: 5 sulfur + oxygen + 4 H2O = sulfite + thiosulfate + 2 hydrogen sulfide + 9 H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "tRNA (adenine-57, 58 N1-) methyltransferase activity"^^xsd:string) AnnotationAssertion( "tRNA (adenine-57, 58-N1-) methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:00706"^^xsd:string) Annotation( "PMID:14739239"^^xsd:string) "Catalysis of the methylation of adenine-57 and adenine-58 in the T-loop of tRNA."^^xsd:string) AnnotationAssertion(rdfs:label "tRNA (adenine-57, 58-N(1)-) methyltransferase activity"^^xsd:string) AnnotationAssertion( "TrmI"^^xsd:string) AnnotationAssertion( "tRNA (m1A) MTase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "SelU"^^xsd:string) AnnotationAssertion(Annotation( "IMG:02609"^^xsd:string) Annotation( "MetaCyc:RXN0-2281"^^xsd:string) "Catalysis of the reaction: 5-methylaminomethyl-2-thiouridine + selenophosphate = 5-methylaminomethyl-2-selenouridine + phosphate (at the wobble position in tRNA)."^^xsd:string) AnnotationAssertion(rdfs:label "tRNA 2-selenouridine synthase activity"^^xsd:string) AnnotationAssertion( "B0503"^^xsd:string) AnnotationAssertion( "YbbB"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:00703"^^xsd:string) Annotation( "PMID:8915538"^^xsd:string) Annotation( "PMID:9707437"^^xsd:string) "Catalysis of the reaction: adenosine-37 + H2O = inosine-37 + NH3, in a tRNA-Ala molecule."^^xsd:string) AnnotationAssertion( "tRNA-specific adenosine deaminase 1"^^xsd:string) AnnotationAssertion( "tRNA(Ala)-A37 deaminase activity"^^xsd:string) AnnotationAssertion( "TAD1"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA-specific adenosine-37 deaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:01366"^^xsd:string) Annotation( "PMID:2509466"^^xsd:string) "Catalysis of the reaction: fumarate + coenzyme M + coenzyme B = succinate + coenzyme M + coenzyme B + heterodisulfide."^^xsd:string) AnnotationAssertion(rdfs:label "thiol-driven fumarate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.5.2"^^xsd:string) "thiosulfate oxidoreductase, tetrathionate-forming activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.5.2"^^xsd:string) "thiosulfate:quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion( "DoxD"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.5.2"^^xsd:string) Annotation( "RHEA:10939"^^xsd:string) "Catalysis of the reaction: 6-decylubiquinone + 2 thiosulfate = 6-decylubiquinol + tetrathionate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.5.2"^^xsd:string) "thiosulfate:6-decylubiquinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiosulfate dehydrogenase (quinone) activity"^^xsd:string) AnnotationAssertion( "thiosulphate:quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion( "TQO"^^xsd:string) AnnotationAssertion( "DoxA"^^xsd:string) AnnotationAssertion( "thiosulphate dehydrogenase (quinone) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "methylcobamide:coenzyme M methyltransferase activity"^^xsd:string) AnnotationAssertion( "trimethylamine-specific methylcobalamin:coenzyme M methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methylamine-specific methylcobalamin:coenzyme M methyltransferase activity"^^xsd:string) AnnotationAssertion( "methylamine-specific methylcobalamin:CoM methyltransferase activity"^^xsd:string) AnnotationAssertion( "MT2-A"^^xsd:string) AnnotationAssertion( "methylcobamide:CoM methyltransferase activity"^^xsd:string) AnnotationAssertion( "methylcobamide:CoM methyltransferase II isozyme A"^^xsd:string) AnnotationAssertion( "dimethylamine-specific methylcobalamin:coenzyme M methyltransferase activity"^^xsd:string) AnnotationAssertion( "MtbA"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01318"^^xsd:string) Annotation( "MetaCyc:RXN-8099"^^xsd:string) "Catalysis of the reaction: a methylated methylamine corrinoid protein + coenzyme M = a methylamine corrinoid protein + methyl-CoM. This reaction is the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M."^^xsd:string) AnnotationAssertion( "monomethylamine-specific methylcobalamin:coenzyme M methyltransferase activity"^^xsd:string) AnnotationAssertion( "MT2"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "MT1"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01323"^^xsd:string) Annotation( "MetaCyc:RXN-8102"^^xsd:string) "Catalysis of the reaction: trimethylamine + a trimethylamine corrinoid protein = a methylated trimethylamine corrinoid protein + dimethylamine."^^xsd:string) AnnotationAssertion( "mttB1"^^xsd:string) AnnotationAssertion( "TMA methyltransferase 1"^^xsd:string) AnnotationAssertion(rdfs:label "trimethylamine methyltransferase activity"^^xsd:string) AnnotationAssertion( "trimethylamine:corrinoid methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:01834"^^xsd:string) Annotation( "MetaCyc:R127-RXN"^^xsd:string) "Catalysis of the reaction: xanthine + H2O = 4-ureido-5-imidazole carboxylate."^^xsd:string) AnnotationAssertion( "xanthinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "xanthine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ValDH"^^xsd:string) AnnotationAssertion(rdfs:label "valine dehydrogenase (NAD) activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:00766"^^xsd:string) Annotation( "PMID:10612726"^^xsd:string) Annotation( "PMID:2803248"^^xsd:string) "Catalysis of the reaction: L-valine + H2O + NAD+ = 3-methyl-2-oxobutanoate + NH3 + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:00182"^^xsd:string) Annotation( "PMID:15795227"^^xsd:string) "Catalysis of the reaction: Kdo2-lipid A + phosphatidylethanolamine = phosphoethanolamine-Kdo2-lipid A + diacylglycerol."^^xsd:string) AnnotationAssertion( "phosphoethanolamine transferase"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylethanolamine:Kdo2-lipid A phosphoethanolamine transferase activity"^^xsd:string) AnnotationAssertion( "EptB"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "lipid A phosphomethyltransferase activity"^^xsd:string) AnnotationAssertion( "lipid A methyltransferase"^^xsd:string) AnnotationAssertion( "lipid A 1-phosphomethyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lipid A phosphate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:02094"^^xsd:string) Annotation( "PMID:15994324"^^xsd:string) "Catalysis of the transfer of a methyl group from S-adenosylmethionine (SAM) to the 1-phosphate group of lipid A."^^xsd:string) AnnotationAssertion( "LmtA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "branched-chain-amino-acid:2-keto-4-methylthiobutyrate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:01684"^^xsd:string) Annotation( "PMID:12670965"^^xsd:string) "Catalysis of the reaction: 2-keto-4-methylthiobutyrate + L-phenylalanine = phenylpyruvate + L-methionine."^^xsd:string) AnnotationAssertion( "BCAT"^^xsd:string) AnnotationAssertion( "branched chain amino acid:2-keto-4-methylthiobutyrate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "branched-chain amino acid:2-keto-4-methylthiobutyrate aminotransferase activity"^^xsd:string) AnnotationAssertion( "branched-chain amino acid aminotransferase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:01546"^^xsd:string) Annotation( "PMID:11535063"^^xsd:string) "Catalysis of the reaction: (S)-lactate + GTP = 2-phospho-(S)-lactate + GDP."^^xsd:string) AnnotationAssertion( "lactate 2-kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(S)-lactate 2-kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "kdtA"^^xsd:string) AnnotationAssertion( "WaaA"^^xsd:string) AnnotationAssertion(Annotation( "IMG:00549"^^xsd:string) Annotation( "PMID:1577828"^^xsd:string) Annotation( "PMID:2033061"^^xsd:string) Annotation( "PMID:9195966"^^xsd:string) "Catalysis of the reactions: (KDO)-lipid IVA + CMP-3-deoxy-D-manno-octulosonate = KDO2-lipid IVA + CMP, and lipid IVA + CMP-3-deoxy-D-manno-octulosonate = (KDO)-lipid IVA + CMP."^^xsd:string) AnnotationAssertion(rdfs:label "Kdo transferase activity"^^xsd:string) AnnotationAssertion( "3-deoxy-D-manno-octulosonic-acid transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.147"^^xsd:string) Annotation( "IMG:01468"^^xsd:string) "Catalysis of the reaction: ADP + D-glucose = AMP + D-glucose 6-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.147"^^xsd:string) "ADP:D-glucose 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ADP-specific glucokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.147"^^xsd:string) "ADP-dependent glucokinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ADP-specific phosphofructokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.146"^^xsd:string) Annotation( "IMG:01469"^^xsd:string) "Catalysis of the reaction: ADP + D-fructose 6-phosphate = AMP + D-fructose 1,6-bisphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.146"^^xsd:string) "ADP-dependent phosphofructokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.146"^^xsd:string) "ADP-Pfk activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.146"^^xsd:string) "ADP-6-phosphofructokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.146"^^xsd:string) "ADP:D-fructose-6-phosphate 1-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cho"^^xsd:string) AnnotationAssertion( "uvrc homolog protein"^^xsd:string) AnnotationAssertion(Annotation( "IMG:00499"^^xsd:string) Annotation( "PMID:11818552"^^xsd:string) "Catalysis of the incision of damaged DNA on the 3' side of a lesion, typically at the ninth phosphodiester bond 3' of the damage."^^xsd:string) AnnotationAssertion( "endonuclease cho"^^xsd:string) AnnotationAssertion(rdfs:label "excinuclease cho activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Ras palmitoyltransferase activity"^^xsd:string) AnnotationAssertion( "ERF2"^^xsd:string) AnnotationAssertion( "Ras protein acyltransferase activity"^^xsd:string) AnnotationAssertion( "DHHC cysteine-rich domain-containing protein ERF2"^^xsd:string) AnnotationAssertion(Annotation( "IMG:00473"^^xsd:string) Annotation( "PMID:16000296"^^xsd:string) "Catalysis of the reaction: palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA, specific for Ras proteins."^^xsd:string) AnnotationAssertion( "palmitoyltransferase ERF2"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:01315"^^xsd:string) Annotation( "MetaCyc:RXN-8096"^^xsd:string) "Catalysis of the reaction: a methylated methanol corrinoid protein + coenzyme M = a methanol corrinoid protein + methyl-CoM. This reaction is the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M."^^xsd:string) AnnotationAssertion( "methanol-specific methylcobalamin: coenzyme M methyltransferase activity"^^xsd:string) AnnotationAssertion( "methyltransferase 2"^^xsd:string) AnnotationAssertion( "methanol-specific methylcobalamin:CoM methyltransferase activity"^^xsd:string) AnnotationAssertion( "MtaC protein:coenzyme M methyltransferase activity"^^xsd:string) AnnotationAssertion( "MtaA"^^xsd:string) AnnotationAssertion( "MT2"^^xsd:string) AnnotationAssertion(rdfs:label "methanol-specific methylcobalamin:coenzyme M methyltransferase activity"^^xsd:string) AnnotationAssertion( "MtaC protein: coenzyme M methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "IMG:01319"^^xsd:string) Annotation( "MetaCyc:RXN-8098"^^xsd:string) "Catalysis of the reaction: monomethylamine + a monomethylamine corrinoid protein = a methylated monomethylamine corrinoid protein + NH3."^^xsd:string) AnnotationAssertion( "MMAMT"^^xsd:string) AnnotationAssertion( "MtmB"^^xsd:string) AnnotationAssertion(rdfs:label "monomethylamine methyltransferase activity"^^xsd:string) AnnotationAssertion( "monomethylamine:corrinoid methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cyclic nucleotide gated mechanosensitive ion channel activity"^^xsd:string) AnnotationAssertion( "cyclic nucleotide regulated mechanosensitive ion channel"^^xsd:string) AnnotationAssertion( "MscS"^^xsd:string) AnnotationAssertion(rdfs:label "cyclic nucleotide-gated mechanosensitive ion channel activity"^^xsd:string) AnnotationAssertion( "cyclic nucleotide-regulated mechanosensitive ion channel"^^xsd:string) AnnotationAssertion( "cyclic nucleotide-regulated small mechanosensitive ion channel"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:02416"^^xsd:string) "Catalysis of the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress and when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion( "small conductance mechanosensitive ion channel"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cyclic nucleotide activated ion channel activity"^^xsd:string) AnnotationAssertion( "cyclic nucleotide gated ion channel activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyclic nucleotide-gated ion channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transmembrane transfer of an ion by a channel that opens when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion( "cyclic nucleotide-activated ion channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:txnOH"^^xsd:string) Annotation( "PMID:15576799"^^xsd:string) "The function of binding to an anti-sigma factor and stopping, preventing or reducing the rate of its activity."^^xsd:string) AnnotationAssertion(rdfs:label "anti-sigma factor antagonist activity"^^xsd:string) AnnotationAssertion( "anti-anti-sigma factor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "AOTC"^^xsd:string) AnnotationAssertion( "acetylornithine transcarbamylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.9"^^xsd:string) "carbamoyl-phosphate:2-N-acetyl-L-ornithine carbamoyltransferase activity"^^xsd:string) AnnotationAssertion( "N-acetylornithine transcarbamylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.9"^^xsd:string) "carbamoyl-phosphate:N2-acetyl-L-ornithine carbamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.9"^^xsd:string) Annotation( "RHEA:18612"^^xsd:string) "Catalysis of the reaction: N(2)-acetyl-L-ornithine + carbamoyl phosphate = N(2)-acetyl-L-citrulline + H(+) + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylornithine carbamoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arginine:ornithine antiporter activity"^^xsd:string) AnnotationAssertion( "ArcD"^^xsd:string) AnnotationAssertion( "arginine/ornithine antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:17110979"^^xsd:string) "Catalysis of the reaction: arginine(out) + ornithine(in) = arginine(in) + ornithine(out)."^^xsd:string) AnnotationAssertion( "arginine-ornithine antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cphA"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.29"^^xsd:string) Annotation( "EC:6.3.2.30"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Catalysis of the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer)."^^xsd:string) AnnotationAssertion(rdfs:label "cyanophycin synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:17028272"^^xsd:string) "Catalysis of the reaction: agmatine(out) + putrescine(in) = agmatine(in) + putrescine(out)."^^xsd:string) AnnotationAssertion(rdfs:label "agmatine:putrescine antiporter activity"^^xsd:string) AnnotationAssertion( "agmatine/putrescine antiporter activity"^^xsd:string) AnnotationAssertion( "agmatine-putrescine antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:17099215"^^xsd:string) "Catalysis of the reaction: arginine(out) + agmatine(in) = arginine(in) + agmatine(out)."^^xsd:string) AnnotationAssertion( "AdiC"^^xsd:string) AnnotationAssertion(rdfs:label "arginine:agmatine antiporter activity"^^xsd:string) AnnotationAssertion( "arginine/agmatine antiporter activity"^^xsd:string) AnnotationAssertion( "arginine-agmatine antiporter activity"^^xsd:string) AnnotationAssertion( "arginine-agmatine exchange transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase activity"^^xsd:string) AnnotationAssertion( "HHED aldolase activity"^^xsd:string) AnnotationAssertion( "HpaI"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:4-HYDROXY-2-KETOPIMELATE-LYSIS-RXN"^^xsd:string) "Catalysis of the reaction: 4-hydroxy-2-ketopimelate = succinate semialdehyde + pyruvate."^^xsd:string) AnnotationAssertion( "HpcH"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxy-2-ketopimelate aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IAH"^^xsd:string) AnnotationAssertion( "indole-3-acetamide hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "indoleacetamide hydrolase activity"^^xsd:string) AnnotationAssertion( "Tms2"^^xsd:string) AnnotationAssertion( "IaaH"^^xsd:string) AnnotationAssertion( "indole acetamide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "MetaCyc:RXNN-404"^^xsd:string) "Catalysis of the reaction: indole-3-acetamide + H2O = indole-3-acetate + NH3. Indole-3-acetamide is known as IAM and indole-3-acetate as IAA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of methionine from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "methionine transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.4.10"^^xsd:string) "AMP,sulfite:thioredoxin-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "adenylyl-sulfate reductase (thioredoxin) activity"^^xsd:string) AnnotationAssertion( "AMP, sulfite:thioredoxin-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming)"^^xsd:string) AnnotationAssertion( "thioredoxin-dependent 5'-adenylylsulfate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.10"^^xsd:string) "Catalysis of the reaction: AMP + sulfite + thioredoxin disulfide = 5'-adenylyl sulfate + thioredoxin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "archaeosine tRNA-ribosyltransferase activity"^^xsd:string) AnnotationAssertion( "TgtA"^^xsd:string) AnnotationAssertion(rdfs:label "7-cyano-7-deazaguanine tRNA-ribosyltransferase activity"^^xsd:string) AnnotationAssertion( "archaeal tRNA-guanine transglycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16407303"^^xsd:string) Annotation( "PMID:7748953"^^xsd:string) "Catalysis of the reaction: tRNA guanine + 7-cyano-7-deazaguanine = tRNA 7-cyano-7-deazaguanine + guanine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-aminoadipate acetyltransferase activity"^^xsd:string) AnnotationAssertion( "LysX"^^xsd:string) AnnotationAssertion( "lysine biosynthesis protein"^^xsd:string) AnnotationAssertion( "RimK"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-5181"^^xsd:string) Annotation( "PMID:10613839"^^xsd:string) Annotation( "PMID:12925802"^^xsd:string) "Catalysis of the reaction: alpha-aminoadipate + acetyl-CoA = N2-acetyl-alpha-aminoadipate + coenzyme A."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-5183"^^xsd:string) "Catalysis of the reaction: N(2)-acetyl-L-aminoadipate-semialdehyde + NADP+ + phosphate = N(2)-acetyl-L-gamma-aminoadipyl phosphate + NADPH."^^xsd:string) AnnotationAssertion( "ArgC"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetyl-gamma-aminoadipyl-phosphate reductase activity"^^xsd:string) AnnotationAssertion( "N-acetyl-aminoadipate semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion( "NAGSA dehydrogenase activity"^^xsd:string) AnnotationAssertion( "AGPR"^^xsd:string) AnnotationAssertion( "LysY"^^xsd:string) AnnotationAssertion( "N-acetyl-alpha-glutamyl-phosphate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "delta1-piperideine-6-carboxylate dehydrogenase activity"^^xsd:string) AnnotationAssertion( "PIPOX"^^xsd:string) AnnotationAssertion( "AmaB"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8162"^^xsd:string) Annotation( "PMID:16237033"^^xsd:string) "Catalysis of the reaction: delta1-piperideine-6-carboxylate + NAD+ + 2 H2O = 2-aminoadipate + NADH + H+. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lysine:cadaverine antiporter activity"^^xsd:string) AnnotationAssertion( "CadB"^^xsd:string) AnnotationAssertion( "lysine-cadaverine antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:10986235"^^xsd:string) Annotation( "TC:2.A.3.2.2"^^xsd:string) "Catalysis of the reaction: lysine(out) + cadaverine(in) = lysine(in) + cadaverine(out)."^^xsd:string) AnnotationAssertion( "lysine/cadaverine antiporter activity"^^xsd:string) AnnotationAssertion( "cadaverine:lysine antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyruvate-flavodoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion( "NifJ"^^xsd:string) AnnotationAssertion(Annotation( "PMID:6352705"^^xsd:string) "Catalysis of the reaction: pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin."^^xsd:string) AnnotationAssertion( "pyruvate:flavodoxin oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "E-1 enolase-phosphatase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.77"^^xsd:string) "5-(methylthio)-2,3-dioxopentyl-phosphate phosphohydrolase (isomerizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.77"^^xsd:string) "Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "acireductone synthase activity"^^xsd:string) AnnotationAssertion( "E-1"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "TdcE"^^xsd:string) AnnotationAssertion( "KFL"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:KETOBUTFORMLY-RXN"^^xsd:string) Annotation( "PMID:9484901"^^xsd:string) "Catalysis of the reaction: 2-oxobutanoate + coenzyme A = propionyl-CoA + formate."^^xsd:string) AnnotationAssertion( "keto-acid formate acetyltransferase"^^xsd:string) AnnotationAssertion(rdfs:label "2-ketobutyrate formate-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "D-allo-TA"^^xsd:string) AnnotationAssertion( "DtaAS"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:4.1.2.42-RXN"^^xsd:string) Annotation( "PMID:9642221"^^xsd:string) "Catalysis of the reaction: D-threonine (or D-allo-threonine) = glycine + acetaldehyde."^^xsd:string) AnnotationAssertion( "D-TA"^^xsd:string) AnnotationAssertion( "D-allo-threonine aldolase activity"^^xsd:string) AnnotationAssertion( "low-specificity D-threonine aldolase"^^xsd:string) AnnotationAssertion(rdfs:label "D-threonine aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "galactosamine-6-phosphate isomerase activity"^^xsd:string) AnnotationAssertion( "galactosamine-6-phosphate deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10931310"^^xsd:string) "Catalysis of the reaction: D-galactosamine 6-phosphate + H2O = D-tagatose 6-phosphate + NH3."^^xsd:string) AnnotationAssertion( "AgaI"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity"^^xsd:string) AnnotationAssertion( "non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NAD)"^^xsd:string) AnnotationAssertion( "glyceraldehyde-3-phosphate dehydrogenase (NAD) activity"^^xsd:string) AnnotationAssertion( "NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion( "glyceraldehyde-3-phosphate dehydrogenase (NAD) (non-phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9497334"^^xsd:string) "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + NAD+ + H2O = 3-phospho-D-glycerate + NADH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glycolic acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "hydroxyacetic acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:28905"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of glycolate from one side of a membrane to the other. Glycolate is the smallest alpha-hydroxy acid (AHA)."^^xsd:string) AnnotationAssertion(rdfs:label "glycolate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "glycolate permease"^^xsd:string) AnnotationAssertion( "glcA"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "crotonyl-coenzyme A reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "InterPro:IPR010085"^^xsd:string) Annotation( "PMID:11162231"^^xsd:string) "Catalysis of the reduction of crotonyl-CoA to butyryl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "crotonyl-CoA reductase activity"^^xsd:string) AnnotationAssertion( "CCR"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mesaconyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion( "beta-methylmalyl-CoA dehydratase activity"^^xsd:string) AnnotationAssertion( "mesaconyl-coenzyme A hydratase activity"^^xsd:string) AnnotationAssertion( "mch"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16856935"^^xsd:string) Annotation( "PMID:16856937"^^xsd:string) "Catalysis of the hydration of mesaconyl-CoA to beta-methylmalyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "malate:sodium cotransporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "malate:sodium symporter activity"^^xsd:string) AnnotationAssertion( "Na+:malate symporter activity"^^xsd:string) AnnotationAssertion( "malate-sodium symporter activity"^^xsd:string) AnnotationAssertion( "sodium:malate symporter activity"^^xsd:string) AnnotationAssertion( "malate Na(+) symporter activity"^^xsd:string) AnnotationAssertion( "malate/sodium cotransporter activity"^^xsd:string) AnnotationAssertion( "sodium/malate symporter activity"^^xsd:string) AnnotationAssertion( "malate:Na+ symporter activity"^^xsd:string) AnnotationAssertion( "sodium-dependent malate transporter"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:10903309"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + Na+(out) = malate(in) + Na+(in)."^^xsd:string) AnnotationAssertion( "Na(+)-malate symporter activity"^^xsd:string) AnnotationAssertion( "malate/sodium symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "MleS"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN8E-5623"^^xsd:string) Annotation( "PMID:3139053"^^xsd:string) "Catalysis of the reaction: malate + H+ = L-lactate + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "malolactic enzyme activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.169"^^xsd:string) Annotation( "PMID:1748656"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + corrinoid protein = CO + methylcorrinoid protein + CoA."^^xsd:string) AnnotationAssertion( "CO-methylating acetyl-coenzyme A synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.169"^^xsd:string) "ACS"^^xsd:string) AnnotationAssertion( "acetyl-CoA:corrinoid protein O-acetyltransferase activity"^^xsd:string) AnnotationAssertion( "acetyl-CoA synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "CO-methylating acetyl-CoA synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "CO-dehydrogenase activity"^^xsd:string) AnnotationAssertion( "CODH"^^xsd:string) AnnotationAssertion( "carbon monoxide dehydrogenase (ferredoxin) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.4"^^xsd:string) "carbon-monoxide dehydrogenase activity"^^xsd:string) AnnotationAssertion( "CO dehydrogenase activity"^^xsd:string) AnnotationAssertion( "carbon-monoxide,water:ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion( "CO-dehydrogenase (ferredoxin) activity"^^xsd:string) AnnotationAssertion(rdfs:label "carbon-monoxide dehydrogenase (ferredoxin) activity"^^xsd:string) AnnotationAssertion( "carbon monoxide dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.4"^^xsd:string) "Catalysis of the reaction: CO + H2O + oxidized ferredoxin = CO2 + reduced ferredoxin."^^xsd:string) AnnotationAssertion( "carbon-monoxide:(acceptor) oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "structural constituent of carboxysome"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "The action of a molecule that contributes to the structural integrity of a carboxysome, an organelle found in the Cyanobacteria consisting of a proteinaceous coat and enzymes for the fixation of carbon dioxide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "melibiose/Na+ symporter activity"^^xsd:string) AnnotationAssertion( "sodium/melibiose symporter activity"^^xsd:string) AnnotationAssertion( "melibiose:Na+ symporter activity"^^xsd:string) AnnotationAssertion( "melibiose/sodium symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "melibiose:sodium symporter activity"^^xsd:string) AnnotationAssertion( "Na+/melibiose symporter activity"^^xsd:string) AnnotationAssertion( "melibiose-Na+ symporter activity"^^xsd:string) AnnotationAssertion( "Na+ (Li+)/melibiose symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:1970646"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + Na+(out) = melibiose(in) + Na+(in)."^^xsd:string) AnnotationAssertion( "melibiose permease"^^xsd:string) AnnotationAssertion( "melibiose-sodium symporter activity"^^xsd:string) AnnotationAssertion( "Na+:melibiose symporter activity"^^xsd:string) AnnotationAssertion( "Na+-melibiose symporter activity"^^xsd:string) AnnotationAssertion( "sodium-melibiose symporter activity"^^xsd:string) AnnotationAssertion( "MelB"^^xsd:string) AnnotationAssertion( "melibiose carrier protein"^^xsd:string) AnnotationAssertion( "sodium:melibiose symporter activity"^^xsd:string) AnnotationAssertion( "thiomethylgalactoside permease II"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2,3-dGGGPS"^^xsd:string) AnnotationAssertion( "UbiA"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15356000"^^xsd:string) Annotation( "PMID:16494480"^^xsd:string) "Catalysis of the transfer of a geranylgeranyl group from geranylgeranyl diphosphate to (S)-3-O-geranylgeranylglyceryl phosphate to form (S)-2,3-di-O-geranylgeranylglyceryl phosphate."^^xsd:string) AnnotationAssertion( "DGGGPS"^^xsd:string) AnnotationAssertion( "DGGGP synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12801917"^^xsd:string) Annotation( "PMID:17253090"^^xsd:string) Annotation( "PMID:8408023"^^xsd:string) "Catalysis of the alkylation of the primary hydroxyl group in (S)-glyceryl phosphate by geranylgeranyl diphosphate to form (S)-3-O-geranylgeranylglyceryl phosphate."^^xsd:string) AnnotationAssertion( "GGGP synthase activity"^^xsd:string) AnnotationAssertion( "(S)-GGGP synthase activity"^^xsd:string) AnnotationAssertion( "(S)-3-O-geranylgeranylglycerylphosphate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(S)-3-O-geranylgeranylglyceryl phosphate synthase activity"^^xsd:string) AnnotationAssertion( "GGGPS"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "chondroitinase"^^xsd:string) AnnotationAssertion( "galactose-6-sulfate sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.4"^^xsd:string) "Catalysis of the hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate."^^xsd:string) AnnotationAssertion( "N-acetylgalactosamine-6-sulfate sulfatase activity"^^xsd:string) AnnotationAssertion( "acetylgalactosamine 6-sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.4"^^xsd:string) "chondroitinsulfatase"^^xsd:string) AnnotationAssertion( "chondroitin sulfatase"^^xsd:string) AnnotationAssertion( "N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase activity"^^xsd:string) AnnotationAssertion( "N-acetylgalactosamine 6-sulfatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylgalactosamine-6-sulfatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.59"^^xsd:string) "NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion( "glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating)"^^xsd:string) AnnotationAssertion( "triosephosphate dehydrogenase (NAD(P))"^^xsd:string) AnnotationAssertion( "D-glyceraldehyde 3-phosphate:NAD(P)+ oxidoreductase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.59"^^xsd:string) "triosephosphate dehydrogenase (NAD(P)+)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.59"^^xsd:string) "Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(rdfs:label "glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.283"^^xsd:string) "Catalysis of the reaction: lactaldehyde + NADP+ = methylglyoxal + NADPH + H+."^^xsd:string) AnnotationAssertion( "lactaldehyde dehydrogenase (NADP+)"^^xsd:string) AnnotationAssertion( "Gre2"^^xsd:string) AnnotationAssertion(rdfs:label "methylglyoxal reductase (NADPH-dependent) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.283"^^xsd:string) "lactaldehyde:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cation/acetate symporter activity"^^xsd:string) AnnotationAssertion( "cation-acetate symporter activity"^^xsd:string) AnnotationAssertion( "ActP"^^xsd:string) AnnotationAssertion( "acetate permease"^^xsd:string) AnnotationAssertion( "acetate-cation symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of acetate from one side of a membrane to the other according to the reaction: acetate(out) + cation(out) = acetate(in) + cation(in)."^^xsd:string) AnnotationAssertion( "cation:acetate symporter activity"^^xsd:string) AnnotationAssertion( "acetate/cation symporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetate:cation symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Pat enzyme"^^xsd:string) AnnotationAssertion( "protein acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15236963"^^xsd:string) "Catalysis of the acetylation of residue Lys609 of the enzyme acetyl-CoA synthetase, using acetyl-CoA as substrate."^^xsd:string) AnnotationAssertion( "Pat"^^xsd:string) AnnotationAssertion(rdfs:label "acetyl-CoA synthetase acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cyclomaltodextrin glycosyltransferase"^^xsd:string) AnnotationAssertion( "beta-cyclodextrin glycosyltransferase"^^xsd:string) AnnotationAssertion( "alpha-cyclodextrin glycosyltransferase"^^xsd:string) AnnotationAssertion( "cyclomaltodextrin glucotransferase"^^xsd:string) AnnotationAssertion( "BMA"^^xsd:string) AnnotationAssertion( "alpha-1,4-glucan 4-glycosyltransferase, cyclizing"^^xsd:string) AnnotationAssertion( "Bacillus macerans amylase"^^xsd:string) AnnotationAssertion( "1,4-alpha-D-glucan 4-alpha-D-(1,4-alpha-D-glucano)-transferase (cyclizing)"^^xsd:string) AnnotationAssertion( "beta-cyclodextrin glucanotransferase"^^xsd:string) AnnotationAssertion( "cyclodextrin glucanotransferase"^^xsd:string) AnnotationAssertion( "alpha-cyclodextrin glucanotransferase"^^xsd:string) AnnotationAssertion( "neutral-cyclodextrin glycosyltransferase"^^xsd:string) AnnotationAssertion( "cyclodextrin glycosyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.19"^^xsd:string) "Catalysis of the cyclization of part of a 1,4-alpha-D-glucan chain by formation of a 1,4-alpha-D-glucosidic bond."^^xsd:string) AnnotationAssertion( "gamma-cyclodextrin glycosyltransferase"^^xsd:string) AnnotationAssertion( "konchizaimu"^^xsd:string) AnnotationAssertion(rdfs:label "cyclomaltodextrin glucanotransferase activity"^^xsd:string) AnnotationAssertion( "CGTase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glucodextrinase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.70"^^xsd:string) "exo-1,6-alpha-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.70"^^xsd:string) "Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in (1->6)-alpha-D-glucans and derived oligosaccharides."^^xsd:string) AnnotationAssertion( "exo-1,6-beta-glucosidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.70"^^xsd:string) "glucodextranase activity"^^xsd:string) AnnotationAssertion( "glucan-1,6-alpha-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.70"^^xsd:string) "glucan alpha-1,6-D-glucohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucan 1,6-alpha-glucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucan 1,4-alpha-maltohydrolase activity"^^xsd:string) AnnotationAssertion( "1,4-alpha-D-glucan alpha-maltohydrolase activity"^^xsd:string) AnnotationAssertion( "glucan-1,4-alpha-maltohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.133"^^xsd:string) "Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive alpha-maltose residues from the non-reducing ends of the chains."^^xsd:string) AnnotationAssertion( "maltogenic alpha-amylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,3-dihydroxybiphenyl 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion( "BphC"^^xsd:string) AnnotationAssertion( "2,3-dihydroxybiphenyl-1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:15715866"^^xsd:string) "Catalysis of the reaction: 2,3-dihydroxybiphenyl + O2 = 2-hydroxy-6-phenylhexa-2,4-dienoic acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "thrH"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:14699121"^^xsd:string) "Catalysis of the transfer of a phosphoryl group from phosphoserine to homoserine to form phosphohomoserine."^^xsd:string) AnnotationAssertion(rdfs:label "phosphoserine:homoserine phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:16248620"^^xsd:string) "Catalysis of the reaction: isochorismate = salicylate + pyruvate."^^xsd:string) AnnotationAssertion( "isochorismate-pyruvate lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "isochorismate pyruvate lyase activity"^^xsd:string) AnnotationAssertion( "IPL"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Ser-tRNAThr hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "Ser-tRNA(Thr) hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:15240874"^^xsd:string) "Catalysis of the hydrolysis of misacylated Ser-tRNA(Thr)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Ala-tRNA(Pro) hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:14663147"^^xsd:string) "Catalysis of the hydrolysis of misacylated Ala-tRNA(Pro)."^^xsd:string) AnnotationAssertion( "Ala-tRNAPro hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Cys-tRNA(Pro) deacetylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "Cys-tRNA(Pro) hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:15886196"^^xsd:string) "Catalysis of the hydrolysis of misacylated Cys-tRNA(Pro)."^^xsd:string) AnnotationAssertion( "Cys-tRNAPro hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Ser(Gly)-tRNA(Ala) hydrolase activity"^^xsd:string) AnnotationAssertion( "Ser(Gly)-tRNAAla hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:14663147"^^xsd:string) "Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala) and Gly-tRNA(Ala)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-acetylcitrulline deacetylase activity"^^xsd:string) AnnotationAssertion( "N-acetyl-L-citrulline deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:02799"^^xsd:string) Annotation( "PMID:16750290"^^xsd:string) "Catalysis of the reaction: N-acetyl-L-citrulline + H2O = citrulline + acetate."^^xsd:string) AnnotationAssertion( "acetylcitrulline deacetylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ATP:coenzyme F420 adenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:02803"^^xsd:string) Annotation( "MetaCyc:RXN-9385"^^xsd:string) Annotation( "PMID:7957247"^^xsd:string) Annotation( "PMID:8550473"^^xsd:string) "Catalysis of the reaction: ATP + factor gamma-F420-2 + H+ = coenzyme F390-A + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "ATP:coenzyme F420 adenylyltransferase activity"^^xsd:string) AnnotationAssertion( "coenzyme F390-A synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "D-lysine aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-lysine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:02956"^^xsd:string) Annotation( "PMID:17259313"^^xsd:string) "Catalysis of the reaction: D-lysine + 2-oxoglutarate = L-glutamate + 6-amino-2-oxohexanoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:02957"^^xsd:string) Annotation( "PMID:17259313"^^xsd:string) "Catalysis of the reaction: D-lysine + O2 + H2O = 6-amino-2-oxohexanoate + NH3 + hydrogen peroxide."^^xsd:string) AnnotationAssertion(rdfs:label "D-lysine oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "NAD(P)H:sulfur oxidoreductase activity"^^xsd:string) AnnotationAssertion( "NSR"^^xsd:string) AnnotationAssertion(rdfs:label "NADPH:sulfur oxidoreductase activity"^^xsd:string) AnnotationAssertion( "coenzyme A-dependent NAD(P)H sulfur oxidoreductase activity"^^xsd:string) AnnotationAssertion( "CoA-dependent NAD(P)H sulfur oxidoreductase activity"^^xsd:string) AnnotationAssertion( "NAD(P)H elemental sulfur oxidoreductase activity"^^xsd:string) AnnotationAssertion( "NAD(P)H sulfur oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:17449625"^^xsd:string) "Catalysis of the reaction: NADPH + H+ + sulfur = hydrogen sulfide + NADP+."^^xsd:string) AnnotationAssertion( "NAD(P)H sulphur oxidoreductase activity"^^xsd:string) AnnotationAssertion( "NADPH:sulphur oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-seryl-tRNA(Sec) kinase activity"^^xsd:string) AnnotationAssertion( "O-phosphoseryl-tRNA(Sec) kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:03019"^^xsd:string) Annotation( "PMID:16201757"^^xsd:string) "Catalysis of the reaction: ATP + L-seryl-tRNA(Sec) = ADP + O-phospho-L-seryl-tRNA(Sec)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:16468998"^^xsd:string) "Catalysis of the reaction: DNA containing 7-methylguanine + H2O = DNA with abasic site + 7-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methylguanine and the deoxyribose sugar to remove the 7-methylguanine, leaving an abasic site."^^xsd:string) AnnotationAssertion(rdfs:label "DNA-7-methylguanine glycosylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ribose-1,5-bisphosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:03024"^^xsd:string) "Catalysis of the reaction: D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "ribose 1,5-bisphosphate isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cadaverine aminopropyl transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cadaverine aminopropyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:00522"^^xsd:string) Annotation( "PMID:17545282"^^xsd:string) "Catalysis of the reaction: S-adenosylmethioninamine + cadaverine = 5'-methylthioadenosine + N-(3-aminopropyl)cadaverine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:03077"^^xsd:string) Annotation( "PMID:15983049"^^xsd:string) "Catalysis of the reaction: agmatine + S-adenosylmethioninamine = N1-aminopropylagmatine + 5'-methylthioadenosine."^^xsd:string) AnnotationAssertion( "agmatine aminopropyl transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "agmatine aminopropyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aminopropylagmatine ureohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:03079"^^xsd:string) Annotation( "PMID:15983049"^^xsd:string) "Catalysis of the reaction: N1-aminopropylagmatine + H2O = spermidine + urea."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Germanin binding"^^xsd:string) AnnotationAssertion(rdfs:label "suramin binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:45906"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) Annotation( "Wikipedia:Suramin"^^xsd:string) "Interacting selectively and non-covalently with suramin, a naphthalenesulfonic acid compound which is used in the treatment of diseases caused by trypanosomes and worms."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "enoyl-CoA hydratase/isomerase"^^xsd:string) AnnotationAssertion( "acetyl-coenzyme A synthetase/GroES-like domain"^^xsd:string) AnnotationAssertion( "AMP-dependent synthetase and ligase"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:11821399"^^xsd:string) "Catalysis of the reaction: 3-hydroxypropionate + ATP + CoA = 3-hydroxypropionyl-CoA + AMP + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxypropionyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion( "acetyl-coenzyme A synthetase"^^xsd:string) AnnotationAssertion( "3-hydroxy propionyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion( "AMP-dependent synthetase and ligase:Enoyl-CoA hydratase/isomerase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "acetyl-coenzyme A synthetase"^^xsd:string) AnnotationAssertion( "AMP-dependent synthetase and ligase"^^xsd:string) AnnotationAssertion( "AMP-dependent synthetase and ligase:Enoyl-CoA hydratase/isomerase"^^xsd:string) AnnotationAssertion( "3-hydroxy propionyl-CoA dehydratase activity"^^xsd:string) AnnotationAssertion( "enoyl-CoA hydratase/isomerase"^^xsd:string) AnnotationAssertion( "acetyl-coenzyme A synthetase/GroES-like domain"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxypropionyl-CoA dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:11821399"^^xsd:string) "Catalysis of the reaction: 3-hydroxypropionyl-CoA = acrylyl-CoA + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "AMP-dependent synthetase and ligase:enoyl-CoA hydratase/isomerase"^^xsd:string) AnnotationAssertion( "AMP-dependent synthetase and ligase"^^xsd:string) AnnotationAssertion( "acetyl-coenzyme A synthetase/GroES-like domain"^^xsd:string) AnnotationAssertion( "enoyl-CoA hydratase/isomerase"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:11821399"^^xsd:string) "Catalysis of the reaction: acryloyl-CoA + NADPH + H+ = propionyl-CoA + NADP+."^^xsd:string) AnnotationAssertion( "acetyl-coenzyme A synthetase"^^xsd:string) AnnotationAssertion( "acryloyl-CoA reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(rdfs:label "acryloyl-CoA reductase (NADP+) activity"^^xsd:string) AnnotationAssertion( "acrylyl-CoA reductase (NADPH) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "acrylyl-CoA reductase (NADH)"^^xsd:string) AnnotationAssertion(rdfs:label "acryloyl-CoA reductase activity"^^xsd:string) AnnotationAssertion( "acryloyl-coenzyme A reductase activity"^^xsd:string) AnnotationAssertion( "propionyl-CoA dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:12603323"^^xsd:string) "Catalysis of the reaction: acryloyl-CoA + NADH + H+ + a reduced electron-transfer flavoprotein = propionyl-CoA + NAD+ + an oxidized electron-transfer flavoprotein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "HpcH/HpaI aldolase"^^xsd:string) AnnotationAssertion(rdfs:label "L-erythro-3-methylmalyl-CoA lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:03303"^^xsd:string) "Catalysis of the reaction: propionyl-CoA + glyoxylate = L-erythro-3-methylmalyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-erythro-3-methylmalyl-CoA dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:03304"^^xsd:string) "Catalysis of the reaction: L-erythro-3-methylmalyl-CoA = mesaconyl-CoA + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "succinyl-CoA:(R)-citramalate CoA-transferase activity"^^xsd:string) AnnotationAssertion( "succinyl-CoA:R-citramalate CoA transferase"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:03306"^^xsd:string) Annotation( "PMID:17259315"^^xsd:string) "Catalysis of the reaction: succinyl-CoA + (R)-citramalate = succinate + (R)-citramalyl-CoA."^^xsd:string) AnnotationAssertion( "L-carnitine dehydratase/bile acid-inducible protein F"^^xsd:string) AnnotationAssertion( "succinyl-CoA:(R)-citramalate CoA transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone acetyltransferase activity (H3-K9 specific)"^^xsd:string) AnnotationAssertion( "histone lysine N-acetyltransferase activity (H3-K9 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 9) = CoA + histone H3 N6-acetyl-L-lysine (position 9)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone acetyltransferase activity (H3-K18 specific)"^^xsd:string) AnnotationAssertion( "histone lysine N-acetyltransferase activity (H3-K18 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 18) = CoA + histone H3 N6-acetyl-L-lysine (position 18)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone acetyltransferase activity (H3-K23 specific)"^^xsd:string) AnnotationAssertion( "histone lysine N-acetyltransferase activity (H3-K23 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 23) = CoA + histone H3 N6-acetyl-L-lysine (position 23)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 5) = CoA + histone H4 N6-acetyl-L-lysine (position 5)."^^xsd:string) AnnotationAssertion(rdfs:label "histone acetyltransferase activity (H4-K5 specific)"^^xsd:string) AnnotationAssertion( "histone lysine N-acetyltransferase activity (H4-K5 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "histone lysine N-acetyltransferase activity (H4-K8 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone acetyltransferase activity (H4-K8 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 8) = CoA + histone H4 N6-acetyl-L-lysine (position 8)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 12) = CoA + histone H4 N6-acetyl-L-lysine (position 12)."^^xsd:string) AnnotationAssertion(rdfs:label "histone acetyltransferase activity (H4-K12 specific)"^^xsd:string) AnnotationAssertion( "histone lysine N-acetyltransferase activity (H4-K12 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "H2A histone acetyltransferase activity"^^xsd:string) AnnotationAssertion( "H2A histone lysine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine = CoA + histone H2A N6-acetyl-L-lysine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 5) = CoA + histone H2A N6-acetyl-L-lysine (position 5)."^^xsd:string) AnnotationAssertion( "histone lysine N-acetyltransferase activity (H2A-K5 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone acetyltransferase activity (H2A-K5 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "histone lysine N-acetyltransferase activity (H2A-K9 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 9) = CoA + histone H2A N6-acetyl-L-lysine (position 9)."^^xsd:string) AnnotationAssertion(rdfs:label "histone acetyltransferase activity (H2A-K9 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "H2B histone lysine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine = CoA + histone H2B N6-acetyl-L-lysine."^^xsd:string) AnnotationAssertion(rdfs:label "H2B histone acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone acetyltransferase activity (H2B-K5 specific)"^^xsd:string) AnnotationAssertion( "histone lysine N-acetyltransferase activity (H2B-K5 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 5) = CoA + histone H2B N6-acetyl-L-lysine (position 5)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 12) = CoA + histone H2B N6-acetyl-L-lysine (position 12)."^^xsd:string) AnnotationAssertion(rdfs:label "histone acetyltransferase activity (H2B-K12 specific)"^^xsd:string) AnnotationAssertion( "histone lysine N-acetyltransferase activity (H2B-K12 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "histone lysine N-acetyltransferase activity (H3-K4 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone acetyltransferase activity (H3-K4 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 4) = CoA + histone H3 N6-acetyl-L-lysine (position 4)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone acetyltransferase activity (H3-K27 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 27) = CoA + histone H3 N6-acetyl-L-lysine (position 27)."^^xsd:string) AnnotationAssertion( "histone lysine N-acetyltransferase activity (H3-K27 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone acetyltransferase activity (H3-K36 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 36) = CoA + histone H3 N6-acetyl-L-lysine (position 36)."^^xsd:string) AnnotationAssertion( "histone lysine N-acetyltransferase activity (H3-K36 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 72) = CoA + histone H3 N6-acetyl-L-lysine (position 72)."^^xsd:string) AnnotationAssertion( "histone lysine N-acetyltransferase activity (H3-K72 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone acetyltransferase activity (H3-K72 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone methyltransferase activity (H4-R3 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histone methylase activity (H4-R3 specific)"^^xsd:string) AnnotationAssertion( "histone-arginine N-methyltransferase activity (H4-R3 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.125"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:17898714"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + (histone H4)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H4)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to arginine at position 3 of histone H4."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "histone serine kinase activity (H3-S28 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone kinase activity (H3-S28 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a phosphate group to the serine-28 residue of the N-terminal tail of histone H3."^^xsd:string) AnnotationAssertion( "histone-serine kinase activity (H3-S28 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "histone-serine kinase activity (H4-S1 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone kinase activity (H4-S1 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a phosphate group to the serine-1 residue of the N-terminal tail of histone H4."^^xsd:string) AnnotationAssertion( "histone serine kinase activity (H4-S1 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone kinase activity (H2A-S1 specific)"^^xsd:string) AnnotationAssertion( "histone-serine kinase activity (H2A-S1 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a phosphate group to the serine-1 residue of the N-terminal tail of histone H2A."^^xsd:string) AnnotationAssertion( "histone serine kinase activity (H2A-S1 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone kinase activity (H2B-S14 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of a phosphate group to the serine-14 or an equivalent residue of the N-terminal tail of histone H2B."^^xsd:string) AnnotationAssertion( "histone-serine kinase activity (H2B-S14 specific)"^^xsd:string) AnnotationAssertion( "histone serine kinase activity (H2B-S14 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "R-citramalyl-CoA lyase activity"^^xsd:string) AnnotationAssertion( "Ccl"^^xsd:string) AnnotationAssertion(rdfs:label "(R)-citramalyl-CoA lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:03307"^^xsd:string) "Catalysis of the reaction: (R)-citramalyl-CoA = pyruvate + acetyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "purine 2'-deoxyribosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "purine deoxyribosyltransferase activity"^^xsd:string) AnnotationAssertion( "PTD"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:03313"^^xsd:string) Annotation( "PMID:11836245"^^xsd:string) "Catalysis of deoxyribose exchange between purine deoxyribonucleoside as a donor and purine base as an acceptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-arabinose 1-dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "IMG:03333"^^xsd:string) "Catalysis of the reaction: L-arabinose + NADP+ = L-arabinono-1,4-lactone + NADPH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,5-dioxovalerate dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion( "2,5-dioxopentanoate dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:03338"^^xsd:string) Annotation( "PMID:16835232"^^xsd:string) Annotation( "PMID:17202142"^^xsd:string) "Catalysis of the reaction: 2,5-dioxopentanoate + NAD+ + H2O = 2-oxoglutarate + NADH + H+."^^xsd:string) AnnotationAssertion( "2,5-dioxopentanoate:NAD+ 5-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-xylulose reductase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "IMG:03341"^^xsd:string) Annotation( "PMID:14736891"^^xsd:string) "Catalysis of the reaction: xylitol + NAD+ = L-xylulose + NADH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "chaperone activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein folding chaperone activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_cambridge_2009"^^xsd:string) "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) that contributes to the process of protein folding."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "RHD binding"^^xsd:string) AnnotationAssertion(rdfs:label "Rel homology domain binding"^^xsd:string) AnnotationAssertion(Annotation( "InterPro:IPR011539"^^xsd:string) Annotation( "Wikipedia:Rel_homology_domain"^^xsd:string) "Interacting selectively and non-covalently with a Rel Homology Domain (RHD) of a protein. The RHD is found in a family of eukaryotic transcription factors, which includes NF-kappaB, Dorsal, Relish and NFAT."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "InterPro:IPR001293"^^xsd:string) "Interacting selectively and non-covalently with a TRAF-type zinc finger domain of a protein."^^xsd:string) AnnotationAssertion( "TRAF-type zinc finger domain binding"^^xsd:string) AnnotationAssertion( "zinc finger TRAF-type domain binding"^^xsd:string) AnnotationAssertion( "zinc-finger-TRAF domain binding"^^xsd:string) AnnotationAssertion(rdfs:label "zf-TRAF domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:txnOH"^^xsd:string) Annotation( "SO:0005836"^^xsd:string) "Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors."^^xsd:string) AnnotationAssertion(rdfs:label "transcription regulatory region DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an intronic DNA region that regulates the transcription of the transcript it is contained within."^^xsd:string) AnnotationAssertion(rdfs:label "intronic transcription regulatory region DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:20149100"^^xsd:string) "Catalysis of the reaction: L-aspartate + fumarate = alpha-iminosuccinate + succinate."^^xsd:string) AnnotationAssertion(rdfs:label "L-aspartate:fumarate oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "retinoic acid-responsive element binding"^^xsd:string) AnnotationAssertion( "RARE binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) Annotation( "GOC:yaf"^^xsd:string) Annotation( "PMID:11327309"^^xsd:string) Annotation( "PMID:19917671"^^xsd:string) "Interacting selectively and non-covalently with a retinoic acid-responsive element, a variable direct repeat of the sequence PuGGTCA spaced by five nucleotides (DR5) found in the promoters of retinoic acid-responsive genes, to which retinoic acid receptors bind."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient."^^xsd:string) AnnotationAssertion(rdfs:label "ion channel binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cytokinin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with a cytokinin, any of a class of adenine-derived compounds that can function in plants as growth regulators."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sequence-specific DNA binding, bending"^^xsd:string) AnnotationAssertion( "DNA bending involving sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "The activity of binding selectively and non-covalently to DNA in a sequence-specific manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II core promoter proximal region sequence-specific DNA binding, bending"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:20123079"^^xsd:string) "The activity of binding selectively and non-covalently to DNA in a sequence-independent manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence."^^xsd:string) AnnotationAssertion( "DNA bending involving non-sequence-specific DNA binding"^^xsd:string) AnnotationAssertion(rdfs:label "non-sequence-specific DNA binding, bending"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with a small protein activating enzyme, such as ubiquitin-activating enzyme."^^xsd:string) AnnotationAssertion(rdfs:label "small protein activating enzyme binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "small conjugating protein ligase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with a small protein ligase, such as ubiquitin-ligase."^^xsd:string) AnnotationAssertion( "E3 protein ligase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "E2 protein ligase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with a small protein conjugating enzyme such as ubiquitin conjugating enzyme."^^xsd:string) AnnotationAssertion(rdfs:label "small protein conjugating enzyme binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glutaryl-CoA thioesterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutaryl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pm"^^xsd:string) Annotation( "PMID:16141203"^^xsd:string) "Catalysis of the reaction: glutaryl-CoA + H2O = CoA + glutarate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:12529935"^^xsd:string) "Combining with glucagon-like peptide 1 and transmitting the signal across the membrane by activating an associated G-protein."^^xsd:string) AnnotationAssertion(rdfs:label "glucagon-like peptide 1 receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "very long chain fatty-acyl-CoA oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "very-long-chain fatty acyl-CoA oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17458872"^^xsd:string) "Catalysis of the reaction: very-long-chain fatty acyl-CoA (C22 - C24) + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide."^^xsd:string) AnnotationAssertion( "VLC fatty-acyl-CoA oxidase activity"^^xsd:string) AnnotationAssertion( "very-long-chain acyl-CoA oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-cystine L-cysteine-lyase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "RHEA:24930"^^xsd:string) "Catalysis of the reaction: L-cystine + H2O <=> pyruvate + NH3 + thiocysteine. Thiocysteine is also known as cysteine persulfide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with a DNA topoisomerase."^^xsd:string) AnnotationAssertion(rdfs:label "DNA topoisomerase binding"^^xsd:string) AnnotationAssertion( "DNA topoisomerase I binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "S100 alpha binding"^^xsd:string) AnnotationAssertion( "S100 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) "Interacting selectively and non-covalently with a S100 protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS."^^xsd:string) AnnotationAssertion( "S100 beta binding"^^xsd:string) AnnotationAssertion(rdfs:label "S100 protein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GTP cyclohydrolase binding"^^xsd:string) AnnotationAssertion( "GTP cyclohydrolase I binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with a GTP cyclohydrolase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cellotriose binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "GOC:tt"^^xsd:string) "Interacting selectively and non-covalently with cellotriose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "GOC:tt"^^xsd:string) Annotation( "PMID:18952792"^^xsd:string) "Interacting selectively and non-covalently with cellodextrin, a glucose polymer of 2 or more glucose monomers."^^xsd:string) AnnotationAssertion(rdfs:label "cellodextrin binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cellobiose binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "GOC:tt"^^xsd:string) "Interacting selectively and non-covalently with cellobiose, a disaccharide that represents the basic repeating unit of cellulose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "GOC:tt"^^xsd:string) "Interacting selectively and non-covalently with cellotetraose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose."^^xsd:string) AnnotationAssertion(rdfs:label "cellotetraose binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cellopentaose binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "GOC:tt"^^xsd:string) "Interacting selectively and non-covalently with cellopentaose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "GOC:tt"^^xsd:string) "Interacting selectively and non-covalently with laminaribiose, a disaccharide."^^xsd:string) AnnotationAssertion(rdfs:label "laminaribiose binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "GOC:tt"^^xsd:string) "Interacting selectively and non-covalently with pectin."^^xsd:string) AnnotationAssertion(rdfs:label "pectin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "iron-sulfur-molybdenum cofactor binding"^^xsd:string) AnnotationAssertion( "FeMo co binding"^^xsd:string) AnnotationAssertion( "FeMoco binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "GOC:tt"^^xsd:string) Annotation( "PMID:18429691"^^xsd:string) "Interacting selectively and non-covalently with iron molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:17074428"^^xsd:string) "Catalysis of the reaction: a 17-beta-hydroxysteroid + NAD+ = a 17-oxosteroid + NADH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "17-beta-hydroxysteroid dehydrogenase (NAD+) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "decaprenyldihydroxybenzoate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10777520"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + 3-decaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-decaprenyl-4-hydroxy-5-methoxybenzoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-demethylubiquinone-10 3-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10777520"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-10 = S-adenosyl-L-homocysteine + ubiquinone-10."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:20651120"^^xsd:string) "Catalysis of the reaction: GTP + protein = diphosphate + guanylyl-protein; mediates the addition of an guanylyl (guanosine 5'-monophosphate; GMP group) to specific residues of target proteins."^^xsd:string) AnnotationAssertion(rdfs:label "protein guanylyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:21734656"^^xsd:string) "protein deAMPylase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:21734656"^^xsd:string) "protein deAMPylation activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein adenylylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:21734656"^^xsd:string) "Catalysis of the reaction: adenylyl-protein+ H2O = adenylate + protein; mediates the removal of an adenylyl (adenosine 5'-monophosphate; AMP group) from specific residues of target proteins."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phytochelatin transmembrane transporter ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:7876244"^^xsd:string) "Catalysis of the reaction: ATP + H2O + phytochelatin (in) = ADP + phosphate + phytochelatin (out)."^^xsd:string) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) Annotation( "http://en.wikipedia.org/wiki/Phytochelatin#History"^^xsd:string) "cadystin transmembrane transporter ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphocholine transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:21822290"^^xsd:string) "Catalysis of the reaction: CDP-choline + protein-serine = CMP + protein-serine-choline phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:22158903"^^xsd:string) "Catalysis of the reaction: protein-serine-choline phosphate + H2O = protein-serine + choline phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "phosphocholine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ans"^^xsd:string) Annotation( "PMID:22185573"^^xsd:string) "Enables the directed movement of flavine mononucleotide (FMN) into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion(rdfs:label "FMN transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "flavine mononucleotide transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ACP phosphopantetheine attachment site binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dextrin alpha-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18556189"^^xsd:string) "Catalysis of the reaction: dextrin + H2O = alpha-D-glucose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "starch alpha-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18556189"^^xsd:string) "Catalysis of the reaction: starch + H2O = alpha-D-glucose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "(R)-carnitine:gamma-butyrobetaine antiporter activity"^^xsd:string) AnnotationAssertion( "L-carnitine:4-(trimethylammonio)butanoate antiporter activity"^^xsd:string) AnnotationAssertion( "L-carnitine:gamma-butyrobetaine antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:crds"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (R)-carnitine(out) + 4-(trimethylammonio)butanoate(in) = (R)-carnitine(in) + 4-(trimethylammonio)butanoate(out)."^^xsd:string) AnnotationAssertion(rdfs:label "(R)-carnitine:4-(trimethylammonio)butanoate antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:crds"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ malonate(out) = sodium(in) + malonate(in)."^^xsd:string) AnnotationAssertion(rdfs:label "sodium:malonate symporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:crds"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ galactoside(out) = sodium(in) + galactoside(in)."^^xsd:string) AnnotationAssertion(rdfs:label "sodium:galactoside symporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:crds"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ alanine(out) = sodium(in) + alanine(in)."^^xsd:string) AnnotationAssertion(rdfs:label "sodium:alanine symporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:17497938"^^xsd:string) "Catalysis of the reaction: GTP + H2O <=> 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + diphosphate +formate + H+. This activity is part of the biosynthesis of methanopterin in Archaea, and requires Fe2+."^^xsd:string) AnnotationAssertion( "Fe(2+)-dependent archaeal-specific GTP cyclohydrolase activity"^^xsd:string) AnnotationAssertion( "MptA activity"^^xsd:string) AnnotationAssertion(rdfs:label "archaeal-specific GTP cyclohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methylthiol:coenzyme M methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8125"^^xsd:string) Annotation( "PMID:9371433"^^xsd:string) "Catalysis of the overall reaction: methyl-Co(III) methylated-thiol-specific corrinoid protein + coenzyme M = Co(I) methylated--thiol-specific corrinoid protein + methyl-CoM."^^xsd:string) AnnotationAssertion( "methylthiol:coenzyme M methyl transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:15028691"^^xsd:string) "Catalysis of the reaction: 7,8-dihydromethanopterin + NADPH = 5,6,7,8-tetrahydromethanopterin + NADP."^^xsd:string) AnnotationAssertion(rdfs:label "dihydromethanopterin reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tetrahydromethanopterin-dependent serine hydroxymethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:12902326"^^xsd:string) "Catalysis of the reaction: tetrahydromethanopterin + L-serine = 5,10-methylenetetrahydromethanopterin + glycine + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:19761441"^^xsd:string) "Catalysis of the reaction: L-phosphoserine + SO32- = L-cysteate + HPO4-."^^xsd:string) AnnotationAssertion(rdfs:label "cysteate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "geranylfarnesyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:20097171"^^xsd:string) "Catalysis of the reaction: geranylgeranyl diphosphate + isopentenyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:19746965"^^xsd:string) "Catalysis of the reaction: 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + H2O = 7,8-dihydroneopterin 3'-phosphate + H+."^^xsd:string) AnnotationAssertion(rdfs:label "7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:11948155"^^xsd:string) Annotation( "PMID:14593448"^^xsd:string) "Catalysis of the reaction: 5-amino-6-(D-ribitylamino)uracil + 4-hydroxyphenylpyruvate + 2 S-adenosyl-L-methionine + H2O = 7,8-didemethyl-8-hydroxy-5-deazariboflavin + 2 5'-deoxyadenosine + 2 L-methionine + oxalate + ammonia + 4 H+."^^xsd:string) AnnotationAssertion( "FO synthase"^^xsd:string) AnnotationAssertion(rdfs:label "7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "exoribonuclease activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rb"^^xsd:string) Annotation( "PMID:22570495"^^xsd:string) "Increases the activity of an exoribonuclease."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11136464"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: trehalose(out) + H+(out) = trehalose(in) + H+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "trehalose:hydrogen symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2-hydroxy-ATP pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pde"^^xsd:string) Annotation( "PMID:11139615"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-adenosine-triphosphate + H2O = 2-hydroxy-adenosine phosphate + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxy-adenosine triphosphate pyrophosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2-hydroxy-(d)ATP pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pde"^^xsd:string) Annotation( "PMID:11139615"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-(deoxy)adenosine-triphosphate + H2O = 2-hydroxy-(deoxy)adenosine phosphate + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:pde"^^xsd:string) Annotation( "PMID:22556419"^^xsd:string) "Catalysis of the reaction 8-oxo-dGDP + H2O = 8-oxo-dGMP + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "8-oxo-dGDP phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:pde"^^xsd:string) Annotation( "PMID:22556419"^^xsd:string) "Catalysis of the reaction 8-oxo-GDP + H2O = 8-oxo-GMP + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "8-oxo-GDP phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:pde"^^xsd:string) Annotation( "PMID:22556419"^^xsd:string) "Catalysis of the reaction8-hydroxy-dADP + H2O = 8-hydroxy-dAMP + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "8-hydroxy-dADP phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "double-stranded hemi-methylated DNA binding"^^xsd:string) AnnotationAssertion(rdfs:label "hemi-methylated DNA-binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:18772889"^^xsd:string) "Interacting selectively and non-covalently with double-stranded hemi-methylated DNA at replication foci (one strand methylated, while the other strand is unmethylated). Cytosine methylation in DNA is an important mechanism for establishing stable heritable epigenetic marks."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "bone sialoprotein II binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10642520"^^xsd:string) "Interacting selectively and non-covalently with a bone sialoprotein, an extracellular matrix glycoprotein found on the surface of bones and dentin."^^xsd:string) AnnotationAssertion(rdfs:label "bone sialoprotein binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transmembrane transfer of a sodium ion by a neuronal, voltage-insensitive channel that opens when a an extracellular proton has been bound by the channel complex."^^xsd:string) AnnotationAssertion(rdfs:label "acid-sensing ion channel activity"^^xsd:string) AnnotationAssertion( "ASIC activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "exonucleolytic trimming to generate 3' end of miRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) "Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming distinct miRNA isoforms from a mature miRNA."^^xsd:string) AnnotationAssertion(rdfs:label "3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the high-affinity transfer of nickel (Ni) cations from one side of a membrane to the other. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations."^^xsd:string) AnnotationAssertion(rdfs:label "high-affinity nickel cation transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of ions from one side of a membrane to the other according to the reaction: ATP + H2O + ion(in) = ADP + phosphate + ion(out), by a rotational mechanism."^^xsd:string) AnnotationAssertion(rdfs:label "ATPase activity, coupled to transmembrane movement of ions, rotational mechanism"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "poly(A)-RNA binding"^^xsd:string) AnnotationAssertion(rdfs:label "poly(A) RNA binding"^^xsd:string) AnnotationAssertion( "poly-A RNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "retroviral integrase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19091057"^^xsd:string) "Catalysis of the covalent insertion of double-stranded retroviral DNA into host DNA. Proceeds by an endonucleolytic cleavage at each 3'-OH extremity of the viral genome, named 3'-processing, followed by a strand transfer reaction leading to the insertion of the processed viral DNA into the target DNA by a trans-esterification mechanism."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3' processing reaction"^^xsd:string) AnnotationAssertion( "3'-processing activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:22580823"^^xsd:string) Annotation( "Reactome:REACT_9069.1"^^xsd:string) "The catalysis of the removal of two di- or tri-nucleotides from each 3' end of double-stranded viral DNA, exposing recessed 3' hydroxyls."^^xsd:string) AnnotationAssertion(rdfs:label "retroviral 3' processing activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "retroviral strand transfer activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:22580823"^^xsd:string) "Catalysis of the covalent insertion of processed 3'-viral DNA ends into host chromosomal DNA by a trans-esterification reaction."^^xsd:string) AnnotationAssertion( "strand transfer reaction"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:1327759"^^xsd:string) "Interacting selectively and non-covalently with a HDEL sequence, the C terminus tetrapeptide sequence His-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum."^^xsd:string) AnnotationAssertion(rdfs:label "HDEL sequence binding"^^xsd:string) AnnotationAssertion( "HDEL receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Interacting selectively and non-covalently with the ends of DNA that are exposed by the creation of double-strand breaks (DSBs)."^^xsd:string) AnnotationAssertion(rdfs:label "DNA end binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "purinergic nucleotide receptor activity, G protein coupled"^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled purinergic nucleotide receptor activity"^^xsd:string) AnnotationAssertion( "G protein coupled purinergic nucleotide receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9755289"^^xsd:string) "Combining with a purine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "purinergic nucleotide receptor activity, G-protein coupled"^^xsd:string) AnnotationAssertion( "G-protein-coupled purinergic nucleotide receptor activity"^^xsd:string) AnnotationAssertion( "P2Y"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9755289"^^xsd:string) "P2Y receptor"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-activated nucleotide receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UDP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UTP-activated nucleotide receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UTP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ATP-activated nucleotide receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by ATP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ADP-activated nucleotide receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by ADP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-18 alpha subunit binding"^^xsd:string) AnnotationAssertion( "IL-18Ra binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10653850"^^xsd:string) "Interacting selectively and non-covalently with the alpha subunit of interleukin-18. IL-18a is a component of IL-18 that is essential for IL-18 binding on the surface of T-helper 1 cells."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-18 beta subunit binding"^^xsd:string) AnnotationAssertion( "IL-18Rb binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10653850"^^xsd:string) "Interacting selectively and non-covalently with the beta subunit of interleukin-18. IL-18b is a ligand non-binding chain and is required for signaling of IL-18 that binds with IL-18a."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "ISBN:3527307206"^^xsd:string) Annotation( "Wikipedia:Azole"^^xsd:string) "Enables the directed movement of azoles, heterocyclic compound found in many biologically important substances, into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion(rdfs:label "azole transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "azole:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion( "bicyclomycin/sulfathiazole:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:3527307206"^^xsd:string) Annotation( "Wikipedia:Azole"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + azole(in) = H+(in) + azole(out). Azoles are heterocyclic compounds found in many biologically important substances."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "azole:proton antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12215548"^^xsd:string) Annotation( "PMID:18216770"^^xsd:string) "Combining with a bioactive lipid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. A bioactive lipid is a lipid for which changes in lipid levels result in functional consequences in a variety of cellular processes."^^xsd:string) AnnotationAssertion(rdfs:label "bioactive lipid receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.59"^^xsd:string) "acetylglucosamine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.59"^^xsd:string) Annotation( "RHEA:17420"^^xsd:string) "Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylglucosamine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.59"^^xsd:string) "2-acetylamino-2-deoxy-D-glucose kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.59"^^xsd:string) "acetylaminodeoxyglucokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.59"^^xsd:string) "ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.59"^^xsd:string) "ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.59"^^xsd:string) "GlcNAc kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "AcuC"^^xsd:string) AnnotationAssertion(rdfs:label "NAD-independent histone deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.17"^^xsd:string) Annotation( "EC:3.5.1.98"^^xsd:string) Annotation( "RHEA:24551"^^xsd:string) "Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction does not require the presence of NAD, and represents the removal of an acetyl group from a histone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.21"^^xsd:string) "3'-phosphoadenylyl-sulfate:keratan 6'-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.21"^^xsd:string) "keratan sulfate sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.21"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + keratan = adenosine 3',5'-bisphosphate + keratan 6'-sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.21"^^xsd:string) "3'-phosphoadenylyl keratan sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.21"^^xsd:string) "3'-phosphoadenylylsulfate:keratan sulfotransferase activity"^^xsd:string) AnnotationAssertion( "keratan sulfate Gal-6-sulfotransferase activity"^^xsd:string) AnnotationAssertion( "keratan sulphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "keratan sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11691992"^^xsd:string) Annotation( "PMID:9722632"^^xsd:string) "Interacting selectively and non-covalently with a pre-mRNA branch point sequence, located upstream of the 3' splice site."^^xsd:string) AnnotationAssertion(rdfs:label "pre-mRNA branch point binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.14"^^xsd:string) "2,3-dihydroxybenzoate oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.14"^^xsd:string) "2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.14"^^xsd:string) "2,3-dihydroxybenzoate 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.14"^^xsd:string) "o-pyrocatechuate oxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2,3-dihydroxybenzoate 3,4-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.14"^^xsd:string) Annotation( "RHEA:18480"^^xsd:string) "Catalysis of the reaction: 2,3-dihydroxybenzoate + O(2) = 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.14"^^xsd:string) "2,3-dihydroxybenzoic oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "uridine-diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "uridine 5'-diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "Catalysis of the reaction: UDP + H2O = UMP + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R00155"^^xsd:string) "UDP phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "UDPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.6"^^xsd:string) "uridine diphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "poly(beta-D-mannuronate) lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.3"^^xsd:string) "alginate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.3"^^xsd:string) "alginate lyase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.3"^^xsd:string) "poly(mana) alginate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.3"^^xsd:string) "alginase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.3"^^xsd:string) "poly(beta-D-1,4-mannuronide) lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.3"^^xsd:string) "alginase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.3"^^xsd:string) "Catalysis of the reaction: polysaccharides containing beta-D-mannuronate residues = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN3O-581"^^xsd:string) Annotation( "PMID:9405490"^^xsd:string) Annotation( "PMID:9614099"^^xsd:string) "Catalysis of the reaction: phytoceramide + inositol phosphate = inositol phosphoceramide."^^xsd:string) AnnotationAssertion(rdfs:label "inositol phosphoceramide synthase activity"^^xsd:string) AnnotationAssertion( "IPC synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "triplex DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10681538"^^xsd:string) "Interacting selectively and non-covalently with a DNA triple helix. The formation of triple helical DNA has been evoked in several cellular processes including transcription, replication, and recombination."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "ssDNA-specific 5'-3' exodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:20086101"^^xsd:string) "Catalysis of the sequential cleavage of nucleotides (such as mononucleotides or dinucleotides) from a free 5' terminus of a single-stranded DNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "single-stranded DNA 5'-3' exodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion( "single-stranded DNA specific 5'-3' exodeoxyribonuclease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.4.11.4"^^xsd:string) "alanine-phenylalanine-proline arylamidase activity"^^xsd:string) AnnotationAssertion( "aminotripeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.11.4"^^xsd:string) "lymphopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.11.4"^^xsd:string) "peptidase B"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.11.4"^^xsd:string) "imidoendopeptidase activity"^^xsd:string) AnnotationAssertion( "peptidase T"^^xsd:string) AnnotationAssertion(rdfs:label "tripeptide aminopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.11.4"^^xsd:string) "Catalysis of the release of the N-terminal residue from a tripeptide."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.4.11.4"^^xsd:string) "aminoexotripeptidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Interacting selectively and non-covalently with an antisigma factor, a factor which inhibits the ability of the sigma factor to function as a transcriptional initiator."^^xsd:string) AnnotationAssertion(rdfs:label "antisigma factor binding"^^xsd:string) AnnotationAssertion( "antisigma factor antagonist activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity"^^xsd:string) AnnotationAssertion( "soluble cytochrome b562"^^xsd:string) AnnotationAssertion( "cytochrome b562"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0716731363"^^xsd:string) "Enables the directed movement of electrons within the CoQH2-cytochrome c reductase complex."^^xsd:string) AnnotationAssertion( "cytochrome"^^xsd:string) AnnotationAssertion( "cytochrome c1"^^xsd:string) AnnotationAssertion( "cytochrome b566"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cytochrome a"^^xsd:string) AnnotationAssertion( "cytochrome a3/copper complex"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0716731363"^^xsd:string) "Enables the directed movement of electrons within the cytochrome c oxidase complex."^^xsd:string) AnnotationAssertion( "cytochrome"^^xsd:string) AnnotationAssertion(rdfs:label "electron transporter, transferring electrons within cytochrome c oxidase complex activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0716731363"^^xsd:string) "Enables the directed movement of electrons from the CoQH2-cytochrome c reductase complex and the cytochrome c oxidase complex."^^xsd:string) AnnotationAssertion(rdfs:label "electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity"^^xsd:string) AnnotationAssertion( "cytochrome"^^xsd:string) AnnotationAssertion( "cytochrome c"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity"^^xsd:string) AnnotationAssertion( "cytochrome bc1 complex"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0716731363"^^xsd:string) "Enables the directed movement of electrons within the cyclic electron transport pathway of photosynthesis."^^xsd:string) AnnotationAssertion( "cytochrome"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "electron transporter, transferring electrons within the noncyclic electron transport pathway of photosynthesis activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0716731363"^^xsd:string) "Enables the directed movement of electrons within the noncyclic electron transport pathway of photosynthesis."^^xsd:string) AnnotationAssertion( "cytochrome"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cytochrome"^^xsd:string) AnnotationAssertion( "cytochrome b/b6"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0716731363"^^xsd:string) "Enables the directed movement of electrons within the cytochrome b6/f complex of photosystem II."^^xsd:string) AnnotationAssertion(rdfs:label "electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity"^^xsd:string) AnnotationAssertion( "cytochrome b6"^^xsd:string) AnnotationAssertion( "cytochrome f"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "myosin II binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html"^^xsd:string) "Interacting selectively and non-covalently with a class II myosin, any member of the class of 'conventional' double-headed myosins that includes muscle myosin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.5.1"^^xsd:string) "glutathione:dehydroascorbate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.5.1"^^xsd:string) "GDOR"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.5.1"^^xsd:string) "DHA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.5.1"^^xsd:string) "dehydroascorbic acid reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.5.1"^^xsd:string) "glutathione:dehydroascorbic acid oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.5.1"^^xsd:string) "glutathione dehydroascorbate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.5.1"^^xsd:string) "dehydroascorbic reductase activity"^^xsd:string) AnnotationAssertion( "dehydroascorbate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.5.1"^^xsd:string) Annotation( "RHEA:24427"^^xsd:string) "Catalysis of the reaction: dehydroascorbate + 2 glutathione = L-ascorbate + glutathione disulfide."^^xsd:string) AnnotationAssertion(rdfs:label "glutathione dehydrogenase (ascorbate) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glutamate synthase activity, NADH or NADPH as acceptor"^^xsd:string) AnnotationAssertion(rdfs:label "glutamate synthase activity, NAD(P)H as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.13"^^xsd:string) Annotation( "EC:1.4.1.14"^^xsd:string) "Catalysis of the reaction: 2 L-glutamate + NAD(P)+ = L-glutamine + 2-oxoglutarate + NAD(P)H + H+."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Any molecular function involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome."^^xsd:string) AnnotationAssertion(rdfs:label "translation regulator"^^xsd:string) AnnotationAssertion( "translation factor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "translation factor activity, non-nucleic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "A translation regulator activity that does not involve binding to nucleic acids."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "alpha chemokine receptor ligand"^^xsd:string) AnnotationAssertion( "alpha chemokine receptor binding"^^xsd:string) AnnotationAssertion( "C-X-C chemokine receptor ligand"^^xsd:string) AnnotationAssertion( "CXC chemokine receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "PMID:11910892"^^xsd:string) "Interacting selectively and non-covalently with a chemokine receptor in the CXCR family."^^xsd:string) AnnotationAssertion(rdfs:label "CXCR chemokine receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "PMID:11910892"^^xsd:string) "Interacting selectively and non-covalently with the CXCR1 chemokine receptor."^^xsd:string) AnnotationAssertion(rdfs:label "CXCR1 chemokine receptor binding"^^xsd:string) AnnotationAssertion( "CXCR1 chemokine receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CXCR2 chemokine receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "PMID:11910892"^^xsd:string) "Interacting selectively and non-covalently with the CXCR2 chemokine receptor."^^xsd:string) AnnotationAssertion( "CXCR2 chemokine receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "luciferase monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "luciferin monooxygenase activity"^^xsd:string) AnnotationAssertion( "luciferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Catalysis of the generalized reaction: luciferin + O2 = oxidized luciferin + CO2 + light. There may be additional substrates and reactants involved in the reaction. The reaction results in light emission as luciferin returns to the ground state after enzymatic oxidation."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-arabinose 1-dehydrogenase [NAD(P)+] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.117"^^xsd:string) "Catalysis of the reaction: D-arabinose + NAD(P)+ = D-arabinono-1,4-lactone + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.117"^^xsd:string) "D-arabinose:NAD(P)+ 1-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Interacting selectively and non-covalently with the alpha subunit of the catenin complex."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-catenin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Interacting selectively and non-covalently with the gamma subunit of the catenin complex."^^xsd:string) AnnotationAssertion(rdfs:label "gamma-catenin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) "plakoglobin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion."^^xsd:string) AnnotationAssertion(rdfs:label "cadherin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.19.2"^^xsd:string) "stearyl-ACP desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.19.2"^^xsd:string) "stearyl acyl carrier protein desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.19.2"^^xsd:string) "Catalysis of the reaction: stearoyl-[acyl-carrier protein] + reduced acceptor + O2 = oleoyl-[acyl-carrier protein] + acceptor + H2O. The enzyme requires ferredoxin."^^xsd:string) AnnotationAssertion(rdfs:label "acyl-[acyl-carrier-protein] desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.19.2"^^xsd:string) "acyl-acyl-carrier-protein, hydrogen-donor:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion( "acyl-[acyl-carrier protein] desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.19.2"^^xsd:string) "acyl-acyl-carrier-protein desaturase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2-methylthio-cis-ribozeatin hydroxylase activity"^^xsd:string) AnnotationAssertion( "tRNA-(ms2io6A)-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity"^^xsd:string) AnnotationAssertion( "tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyladenosine)-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) Annotation( "PMID:8253666"^^xsd:string) "Catalysis of the reaction: tRNA-(2-methylthio-N-6-isopentenyl adenosine) = tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine) + O2. 2-methylthio-N-6-isopentenyl adenosine is also known as ms2i6A; 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine is also known as ms2io6A and 2-methylthio-cis-ribozeatin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.24"^^xsd:string) "choloyltaurine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.24"^^xsd:string) "glycocholase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.24"^^xsd:string) "3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "choloylglycine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.24"^^xsd:string) "bile salt hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.24"^^xsd:string) "Catalysis of the reaction: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholan-24-oylglycine + H2O = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + glycine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.76"^^xsd:string) "DABA aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.76"^^xsd:string) "2,4-diaminobutyrate 4-aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.76"^^xsd:string) "diaminobutyrate--2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.76"^^xsd:string) "L-2,4-diaminobutyrate:2-oxoglutarate 4-aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.76"^^xsd:string) "diaminobutyrate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.76"^^xsd:string) Annotation( "RHEA:11163"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + L-2,4-diaminobutyrate = L-aspartate 4-semialdehyde + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.76"^^xsd:string) "L-2,4-diaminobutanoate:2-oxoglutarate 4-aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.76"^^xsd:string) "DAB aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.76"^^xsd:string) "L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.76"^^xsd:string) "EctB"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.76"^^xsd:string) "diaminibutyric acid aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "diaminobutyrate-2-oxoglutarate transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein phosphorylated amino acid binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with a phosphorylated amino acid residue within a protein."^^xsd:string) AnnotationAssertion( "phosphoprotein amino acid binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:10688657"^^xsd:string) "Interacting selectively and non-covalently with unmethylated CpG motifs. Unmethylated CpG dinucleotides are often associated with gene promoters."^^xsd:string) AnnotationAssertion(rdfs:label "unmethylated CpG binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aspartyl esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "UniProtKB-KW:KW-0063"^^xsd:string) "Catalysis of the hydrolysis of an ester bond by a mechanism involving a catalytically active aspartic acid residue."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "mercury binding"^^xsd:string) AnnotationAssertion(rdfs:label "mercury ion binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with mercury (Hg) ions."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ebc"^^xsd:string) "Blocks the binding of interleukin-1 to interleukin-1 Type I receptors."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-1 Type I receptor antagonist activity"^^xsd:string) AnnotationAssertion( "IL-1ra type I"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-1ra type II"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ebc"^^xsd:string) "Blocks the binding of interleukin-1 to interleukin-1 Type II receptors."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-1 Type II receptor antagonist activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.5.1.6"^^xsd:string) "chalcone--flavonone isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.6"^^xsd:string) "Catalysis of the reaction: a chalcone = a flavanone."^^xsd:string) AnnotationAssertion( "chalcone-flavanone isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "chalcone isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.6"^^xsd:string) "flavanone lyase (decyclizing)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.23"^^xsd:string) "flavonoid 2-oxoglutarate-dependent dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.23"^^xsd:string) "dihydroflavonol,2-oxoglutarate:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.23"^^xsd:string) Annotation( "ISBN:0943088372"^^xsd:string) Annotation( "PMID:7904213"^^xsd:string) "Catalysis of the reaction: a dihydroflavonol + 2-oxoglurate + O2 = a flavonol + succinate + CO2 + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "flavonol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.23"^^xsd:string) "FLS activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "lycopene cyclase"^^xsd:string) AnnotationAssertion(rdfs:label "lycopene epsilon cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8837512"^^xsd:string) "Catalysis of the cyclization of an epsilon ring at one end of the lycopene molecule (psi, psi-carotene) to form delta-carotene (epsilon, psi-carotene)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:8837512"^^xsd:string) "Catalysis of the cyclization of beta rings at one or both ends of the lycopene molecule (psi, psi-carotene) to form gamma-carotene or the bicyclic beta-carotene (beta, beta-carotene), respectively."^^xsd:string) AnnotationAssertion(rdfs:label "lycopene beta cyclase activity"^^xsd:string) AnnotationAssertion( "crtL"^^xsd:string) AnnotationAssertion( "lycopene cyclase"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "uridine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.3"^^xsd:string) Annotation( "RHEA:15580"^^xsd:string) "Catalysis of the reaction: H(2)O + uridine = ribofuranose + uracil."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.3"^^xsd:string) "uridine ribohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "uridine nucleosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:1572368"^^xsd:string) Annotation( "PMID:2061333"^^xsd:string) "Catalysis of the formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine from constituent amino acids and ATP in the presence of magnesium ions and dithioerythritol."^^xsd:string) AnnotationAssertion( "ACV synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "isopenicillin-N epimerase activity"^^xsd:string) AnnotationAssertion( "isopenicillin N epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.17"^^xsd:string) "penicillin-N 5-amino-5-carboxypentanoyl-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.17"^^xsd:string) Annotation( "RHEA:20036"^^xsd:string) "Catalysis of the reaction: isopenicillin N = penicillin N."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.26"^^xsd:string) "3'-methylcephem hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.26"^^xsd:string) "DACS"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.26"^^xsd:string) "DAOC hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.26"^^xsd:string) Annotation( "RHEA:16808"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + deacetoxycephalosporin C + O(2) = CO(2) + deacetylcephalosporin C + succinate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.26"^^xsd:string) "deacetylcephalosporin C synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "deacetoxycephalosporin-C hydroxylase activity"^^xsd:string) AnnotationAssertion( "beta-lactam hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.26"^^xsd:string) "deacetoxycephalosporin C hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.26"^^xsd:string) "deacetoxycephalosporin-C,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10583973"^^xsd:string) "Catalysis of the 3-O-acetylation of a trichothecene. Trichothecenes are sesquiterpene epoxide mycotoxins that act as potent inhibitors of eukaryotic protein synthesis."^^xsd:string) AnnotationAssertion(rdfs:label "trichothecene 3-O-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.9"^^xsd:string) "beta-galactose oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactose oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.9"^^xsd:string) "D-galactose oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.9"^^xsd:string) "Catalysis of the reaction: D-galactose + O2 = D-galacto-hexodialdose + hydrogen peroxide."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.9"^^xsd:string) "D-galactose:oxygen 6-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.241"^^xsd:string) "6-endo-hydroxycineole:NAD+ 6-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.241"^^xsd:string) Annotation( "RHEA:11739"^^xsd:string) "Catalysis of the reaction: 6-endo-hydroxycineole + NAD(+) = 6-oxocineole + H(+) + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "6-endo-hydroxycineole dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.6"^^xsd:string) "trans,trans-farnesyl-diphosphate sesquiterpenoid-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.6"^^xsd:string) "trichodiene synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.6"^^xsd:string) Annotation( "RHEA:12055"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + trichodiene."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.6"^^xsd:string) "trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, trichodiene-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.6"^^xsd:string) "sesquiterpene cyclase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trichodiene synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.9"^^xsd:string) "sesquiterpene cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.9"^^xsd:string) "trans,trans-farnesyl diphosphate aristolochene-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.9"^^xsd:string) "trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.9"^^xsd:string) "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.9"^^xsd:string) "5-epi-aristolochene synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aristolochene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.9"^^xsd:string) "Catalysis of the reaction: trans,trans-farnesyl diphosphate = aristolochene + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.36"^^xsd:string) "L-lysine-alpha-ketoglutarate 6-aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.36"^^xsd:string) "lysine:2-ketoglutarate 6-aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-lysine 6-transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.36"^^xsd:string) Annotation( "RHEA:21203"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + L-lysine = L-glutamate + allysine."^^xsd:string) AnnotationAssertion( "lysine 6-aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.36"^^xsd:string) "lysine epsilon-aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.36"^^xsd:string) "L-lysine:2-oxoglutarate 6-aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.36"^^xsd:string) "L-lysine-alpha-ketoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.36"^^xsd:string) "lysine epsilon-transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.36"^^xsd:string) "L-lysine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.36"^^xsd:string) "L-lysine aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:7846158"^^xsd:string) "Catalysis of the introduction of an omega-6 double bond into the fatty acid hydrocarbon chain."^^xsd:string) AnnotationAssertion(rdfs:label "omega-6 fatty acid desaturase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.9"^^xsd:string) "flavanone 3-beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "naringenin 3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.9"^^xsd:string) "flavanone 3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.9"^^xsd:string) "Catalysis of the reaction: naringenin + 2-oxoglutarate + O2 = dihydrokaempferol + succinate + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.9"^^xsd:string) "(2S)-flavanone 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.9"^^xsd:string) "flavanone 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.9"^^xsd:string) "naringenin 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.9"^^xsd:string) "flavanone synthase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.9"^^xsd:string) "naringenin,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.9"^^xsd:string) "flavanone 3beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.9"^^xsd:string) "flavanone,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chemorepellent activity"^^xsd:string) AnnotationAssertion( "chemorepellant activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a lower concentration of that signal."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Interacting selectively and non-covalently with dynein, the multisubunit protein complex that is associated with microtubules."^^xsd:string) AnnotationAssertion(rdfs:label "dynein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Interacting selectively and non-covalently with a light chain of the dynein complex."^^xsd:string) AnnotationAssertion(rdfs:label "dynein light chain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dynein heavy chain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Interacting selectively and non-covalently with a heavy chain of the dynein complex."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Interacting selectively and non-covalently with an intermediate chain of the dynein complex."^^xsd:string) AnnotationAssertion(rdfs:label "dynein intermediate chain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-24 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-24 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-24 receptor activity"^^xsd:string) AnnotationAssertion( "IL-24R"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-25 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-25 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-25 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion( "IL-25R"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-26 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-26 receptor activity"^^xsd:string) AnnotationAssertion( "IL-26R"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-26 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "IL-27R"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-27 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-27 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IL-27 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with interleukin-24."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-24 binding"^^xsd:string) AnnotationAssertion( "IL-24 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-25 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with interleukin-25."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-25 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-26 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with interleukin-26."^^xsd:string) AnnotationAssertion( "IL-26 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-27 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with interleukin-27."^^xsd:string) AnnotationAssertion( "IL-27 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-16"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-16 receptor."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-16 receptor binding"^^xsd:string) AnnotationAssertion( "interleukin-16 receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-18 receptor."^^xsd:string) AnnotationAssertion( "IL-18"^^xsd:string) AnnotationAssertion( "interleukin-18 receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-18 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-19 receptor."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-19 receptor binding"^^xsd:string) AnnotationAssertion( "IL-19"^^xsd:string) AnnotationAssertion( "interleukin-19 receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-20 receptor."^^xsd:string) AnnotationAssertion( "IL-20"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-20 receptor binding"^^xsd:string) AnnotationAssertion( "interleukin-20 receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-22 receptor binding"^^xsd:string) AnnotationAssertion( "interleukin-22 receptor ligand"^^xsd:string) AnnotationAssertion( "IL-22"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-22 receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-23 receptor."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-23 receptor binding"^^xsd:string) AnnotationAssertion( "interleukin-23 receptor ligand"^^xsd:string) AnnotationAssertion( "IL-23"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "interleukin-24 receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-24 receptor."^^xsd:string) AnnotationAssertion( "IL-24"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-24 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-25 receptor."^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-25 receptor binding"^^xsd:string) AnnotationAssertion( "IL-25"^^xsd:string) AnnotationAssertion( "interleukin-25 receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IL-26"^^xsd:string) AnnotationAssertion( "interleukin-26 receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-26 receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-26 receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-27 receptor."^^xsd:string) AnnotationAssertion( "IL-27"^^xsd:string) AnnotationAssertion( "interleukin-27 receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-27 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.13"^^xsd:string) "gibberellin 2beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.13"^^xsd:string) "(gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.13"^^xsd:string) "gibberellin 2beta-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.13"^^xsd:string) "gibberellin 2-beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "gibberellin 2-beta-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.13"^^xsd:string) Annotation( "GOC:kad"^^xsd:string) "Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 2-beta-hydroxygibberellin + succinate + CO2."^^xsd:string) AnnotationAssertion( "gibberellin 2-oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "gibberellin 20-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:7604047"^^xsd:string) "Catalysis of the oxidation of C-20 gibberellins to form the corresponding C-19 lactones."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "PMID:9355727"^^xsd:string) "Interacting selectively and non-covalently with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells."^^xsd:string) AnnotationAssertion(rdfs:label "syndecan binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:9858571"^^xsd:string) "Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "dehydrodolichyl diphosphate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "RHEA:21387"^^xsd:string) "Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate."^^xsd:string) AnnotationAssertion(rdfs:label "phenylalanine ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.24"^^xsd:string) "PAL activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.24"^^xsd:string) "phenylalanine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.24"^^xsd:string) "L-phenylalanine ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.24"^^xsd:string) "phenylalanine ammonium-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.24"^^xsd:string) "phe ammonia-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "9-cis-epoxycarotenoid dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.51"^^xsd:string) "9-cis-epoxycarotenoid 11,12-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.51"^^xsd:string) "PvNCED1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.51"^^xsd:string) "nine-cis-epoxycarotenoid dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.51"^^xsd:string) "VP14"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.51"^^xsd:string) "NCED"^^xsd:string) AnnotationAssertion( "neoxanthin cleavage enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.51"^^xsd:string) "Catalysis of the reactions: a 9-cis-epoxycarotenoid + O2 = 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal; 9-cis-violaxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al; and 9'-cis-neoxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6R)-5,6-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.51"^^xsd:string) "AtNCED3"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "geranylgeranyl reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9492312"^^xsd:string) "Catalysis of the formation of phytyl group from the stepwise reduction of a geranylgeranyl group."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.195"^^xsd:string) "Catalysis of the reaction: cinnamyl alcohol + NADP+ = cinnamaldehyde + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.195"^^xsd:string) "cinnamyl alcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.195"^^xsd:string) "cinnamyl-alcohol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.195"^^xsd:string) "CAD activity"^^xsd:string) AnnotationAssertion(rdfs:label "cinnamyl-alcohol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.219"^^xsd:string) "dihydromyricetin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.219"^^xsd:string) "Catalysis of the reaction: cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.219"^^xsd:string) "NADPH-dihydromyricetin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.219"^^xsd:string) "dihydroquercetin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.219"^^xsd:string) "dihydroflavanol 4-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.219"^^xsd:string) "cis-3,4-leucopelargonidin:NADP+ 4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.219"^^xsd:string) "dihydroflavonol 4-reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dihydrokaempferol 4-reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Apo-2L binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) Annotation( "PMID:9082980"^^xsd:string) "Interacting selectively and non-covalently with TRAIL (TNF-related apoptosis inducing ligand), a member of the tumor necrosis factor ligand family that rapidly induces apoptosis in a variety of transformed cell lines."^^xsd:string) AnnotationAssertion(rdfs:label "TRAIL binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ketoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.-.-"^^xsd:string) "Catalysis of the reduction of a ketone group to form the corresponding alcohol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "storage protein of fat body"^^xsd:string) AnnotationAssertion( "yolk protein"^^xsd:string) AnnotationAssertion(rdfs:label "molecular nutrient reservoir"^^xsd:string) AnnotationAssertion( "storage protein"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Functions in the storage of nutritious substrates."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "precorrin-6Y C5,15-methyltransferase (decarboxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.132"^^xsd:string) "precorrin-6Y methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.132"^^xsd:string) "precorrin-6 methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.132"^^xsd:string) "Catalysis of the reaction: 2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.132"^^xsd:string) "S-adenosyl-L-methionine:1-precorrin-6Y C5,15-methyltransferase (C-12-decarboxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "precorrin-4 C11-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.133"^^xsd:string) "S-adenosyl-L-methionine:precorrin-4 C11 methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.133"^^xsd:string) "CobM"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.133"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-4 = S-adenosyl-L-homocysteine + precorrin 5."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.158"^^xsd:string) "phospholipid:1,2-diacyl-sn-glycerol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.158"^^xsd:string) "Catalysis of the reaction: phospholipid + 1,2-diacylglycerol = lysophospholipid + triacylglycerol."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.158"^^xsd:string) "PDAT activity"^^xsd:string) AnnotationAssertion(rdfs:label "phospholipid:diacylglycerol acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0716731363"^^xsd:string) "Enables the directed movement of electrons from the cytochrome b6/f complex of photosystem II."^^xsd:string) AnnotationAssertion(rdfs:label "electron transporter, transferring electrons from cytochrome b6/f complex of photosystem II activity"^^xsd:string) AnnotationAssertion( "plastocyanin"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.255"^^xsd:string) "mannitol:NAD+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.255"^^xsd:string) Annotation( "RHEA:15032"^^xsd:string) "Catalysis of the reaction: D-mannitol + NAD(+) = D-mannose + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.255"^^xsd:string) "MTD activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.255"^^xsd:string) "NAD-dependent mannitol dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannitol dehydrogenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IP(3) phosphatase activity"^^xsd:string) AnnotationAssertion( "inositol-1,4,5-trisphosphate phosphatase"^^xsd:string) AnnotationAssertion(rdfs:label "inositol trisphosphate phosphatase activity"^^xsd:string) AnnotationAssertion( "IP3 phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Catalysis of the reaction: myo-inositol trisphosphate + H2O = myo-inositol bisphosphate + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.12"^^xsd:string) Annotation( "RHEA:19436"^^xsd:string) "Catalysis of the reaction: D-gluconate + ATP = 6-phospho-D-gluconate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.12"^^xsd:string) "gluconokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "gluconokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.12"^^xsd:string) "gluconate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.12"^^xsd:string) "ATP:D-gluconate 6-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a SMAD signaling protein."^^xsd:string) AnnotationAssertion(rdfs:label "SMAD binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.81"^^xsd:string) "acetyl-CoA:2-deoxystreptamine-antibiotic N3'-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.81"^^xsd:string) "3-N-aminoglycoside acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aminoglycoside 3-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.81"^^xsd:string) "3'-aminoglycoside acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 3-N-acetylaminoglycoside. This is acetylation of the 3-amino group of the central deoxystreptamine ring."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.60"^^xsd:string) "aminoglycoside acetyltransferase AAC(3)-I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.60"^^xsd:string) "gentamycin acetyltransferase I"^^xsd:string) AnnotationAssertion( "gentamicin 3'-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.60"^^xsd:string) "aminoglycoside acetyltransferase AAC(3)-1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.60"^^xsd:string) "gentamicin acetyltransferase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.81"^^xsd:string) "gentamicin-(3)-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion( "gentamycin 3'-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.60"^^xsd:string) "acetyl-CoA:gentamicin-C N3'-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "polynucleotide 3'-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.32"^^xsd:string) "deoxyribonucleate 3'-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.32"^^xsd:string) "5'-polynucleotidekinase 3'-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.32"^^xsd:string) "DNA 3'-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.32"^^xsd:string) "polynucleotide 3'-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.32"^^xsd:string) "Catalysis of the reaction: 3'-phosphopolynucleotide + H2O = a polynucleotide + phosphate. Hydrolyzes the free 3'-phosphate resulting from single strand breaks in DNA due to oxidative damage."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.32"^^xsd:string) "2'(3')-polynucleotidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.78"^^xsd:string) "Catalysis of the reaction: ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA."^^xsd:string) AnnotationAssertion(rdfs:label "ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity"^^xsd:string) AnnotationAssertion( "ATP-dependent DNA kinase activity"^^xsd:string) AnnotationAssertion( "ATP:5'-dephosphopolydeoxyribonucleotide 5'-phosphotransferase activity"^^xsd:string) AnnotationAssertion( "ATP-dependent DNA 5'-hydroxyl-kinase activity"^^xsd:string) AnnotationAssertion( "ATP-dependent polynucleotide 5'-hydroxyl-kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.30"^^xsd:string) "glycerol hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.30"^^xsd:string) "glycerol hydro-lyase (3-hydroxypropanal-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.30"^^xsd:string) "glycerol dehydrase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycerol dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.30"^^xsd:string) Annotation( "PMID:18307109"^^xsd:string) "Catalysis of the reaction: glycerol = 3-hydroxypropanal + H2O."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.11"^^xsd:string) "S-adenosyl-L-methionine:Mg protoporphyrin methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.11"^^xsd:string) Annotation( "RHEA:17812"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + magnesium protoporphyrin IX = S-adenosyl-L-homocysteine + H(+) + magnesium protoporphyrin IX 13-monomethyl ester."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.11"^^xsd:string) "S-adenosylmethioninemagnesium protoporphyrin methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.11"^^xsd:string) "(-)-S-adenosyl-L-methionine:magnesium-protoporphyrin IX methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.11"^^xsd:string) "S-adenosyl-L-methionine:magnesium-protoporphyrin O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.11"^^xsd:string) "Mg-protoporphyrin IX methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.11"^^xsd:string) "S-adenosyl-L-methionine:magnesium-protoporphyrin-IX O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "magnesium protoporphyrin IX methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.11"^^xsd:string) "S-adenosylmethionine-magnesium protoporphyrin methyltransferase activity"^^xsd:string) AnnotationAssertion( "magnesium-protoporphyrin O-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chlorophyll synthetase activity"^^xsd:string) AnnotationAssertion( "chlorophyll synthase activity"^^xsd:string) AnnotationAssertion( "chlorophyllide-a:phytyl-diphosphate phytyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.62"^^xsd:string) Annotation( "RHEA:17320"^^xsd:string) "Catalysis of the reaction: chlorophyllide a + 2 H(+) + phytyl diphosphate = chlorophyll a + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cytochrome P450 CYP98A3"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11429408"^^xsd:string) Annotation( "PMID:11891223"^^xsd:string) "Catalysis of the reaction: shikimate or quinate ester of p-coumaric acid + NADPH + H+ + O2 = caffeic acid conjugate (caffeoyl shikimic acid or chlorogenic acid) + H2O + NADP+."^^xsd:string) AnnotationAssertion(rdfs:label "p-coumarate 3-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3.30"^^xsd:string) Annotation( "RHEA:16812"^^xsd:string) "Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate."^^xsd:string) AnnotationAssertion( "2-methylisocitrate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.30"^^xsd:string) "MICL"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.30"^^xsd:string) "(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.30"^^xsd:string) "(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase (succinate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "methylisocitrate lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "violaxanthin de-epoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.99.3"^^xsd:string) "VDE"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.99.3"^^xsd:string) "violaxanthin:ascorbate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.99.3"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0471331309"^^xsd:string) "Catalysis of the reaction: violaxanthin + 2 ascorbate = zeaxanthin + 2 dehydroascorbate + 2 H2O; and antheraxanthin + ascorbate = zeaxanthin + dehydroascorbate + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.99.6"^^xsd:string) "(9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate isomerase (cyclizing)"^^xsd:string) AnnotationAssertion(rdfs:label "allene-oxide cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.6"^^xsd:string) Annotation( "RHEA:22595"^^xsd:string) "Catalysis of the reaction: (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate = (15Z)-12-oxophyto-10,15-dienoate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ferulate 5-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8692910"^^xsd:string) Annotation( "PMID:9880351"^^xsd:string) "Catalysis of the reaction: ferulic acid + NADPH + H+ + O2 = 5-hydroxyferulic acid + H2O + NADP+."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "1,4-Dihydroxy-2-naphtoate prenyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1,4-dihydroxy-2-naphthoate octaprenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:DMK-RXN"^^xsd:string) "Catalysis of the reaction: 1,4-dihydroxy-2-naphthoate + polyprenylpyrophosphate = dimethylmenaquinone + diphosphate + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.17.7.1"^^xsd:string) Annotation( "PMID:11752431"^^xsd:string) "Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + 2 oxidized ferredoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + 2 reduced ferredoxin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.7.1"^^xsd:string) "(E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.7.1"^^xsd:string) Annotation( ) "(E)-4-hydroxy-3-methylbut-2-en-1-yl-diphosphate:oxidized ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:HYDROXY-METHYL-BUTENYL-DIP"^^xsd:string) "1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:HYDROXY-METHYL-BUTENYL-DIP"^^xsd:string) "1-hydroxy-2-methyl-2-butenyl 4-diphosphate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.184"^^xsd:string) "digalactosyldiacylglycerol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.184"^^xsd:string) "Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = alpha-D-galactosyl-beta-D-galactosyldiacylglycerol + 1,2-diacylglycerol."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.184"^^xsd:string) "GGGT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.184"^^xsd:string) "galactolipid-galactolipid galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "galactolipid:galactolipid galactosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactolipid galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.184"^^xsd:string) "DGDG synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.184"^^xsd:string) "3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol:mono-3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol beta-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.184"^^xsd:string) "interlipid galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "UDP-galactose:MGDG galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.241"^^xsd:string) "DGDG synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.241"^^xsd:string) "UDP-galactose-dependent digalactosyldiacylglycerol synthase activity"^^xsd:string) AnnotationAssertion( "DGD2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.241"^^xsd:string) Annotation( "RHEA:10523"^^xsd:string) "Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + UDP-D-galactose = 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-glycerol + H(+) + UDP."^^xsd:string) AnnotationAssertion( "DGD1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.241"^^xsd:string) "UDP-galactose:3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol 6-alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "digalactosyldiacylglycerol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.241"^^xsd:string) "UDP-galactose-dependent DGDG synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDPsulfoquinovose synthase activity"^^xsd:string) AnnotationAssertion( "sulfite:UDP-glucose sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.13.1.1"^^xsd:string) Annotation( "RHEA:13200"^^xsd:string) "Catalysis of the reaction: sulfite + UDP-D-glucose = H(2)O + UDP-6-sulfoquinovose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.13.1.1"^^xsd:string) "UDP-sulfoquinovose synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.13.1.1"^^xsd:string) "UDP-6-sulfo-6-deoxyglucose sulfohydrolase activity"^^xsd:string) AnnotationAssertion( "UDPsulphoquinovose synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydrolase activity, acting on carbon-sulfur bonds"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the hydrolysis of any carbon-sulfur bond, C-S."^^xsd:string) AnnotationAssertion( "hydrolase activity, acting on carbon-sulphur bonds"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "monogalactosyldiacylglycerol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.46"^^xsd:string) Annotation( "RHEA:14948"^^xsd:string) "Catalysis of the reaction: 1,2-diacyl-sn-glycerol + UDP-D-galactose = 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + H(+) + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.46"^^xsd:string) "1beta-MGDG"^^xsd:string) AnnotationAssertion( "UDP galactose-1,2-diacylglycerol galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.46"^^xsd:string) "UDP-galactose:1,2-diacyl-sn-glycerol 3-beta-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "uridine diphosphogalactose-1,2-diacylglycerol galactosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1,2-diacylglycerol 3-beta-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.46"^^xsd:string) "UDPgalactose:1,2-diacylglycerol 3-beta-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "UDP-galactose:diacylglycerol galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.46"^^xsd:string) "1-beta-MGDG activity"^^xsd:string) AnnotationAssertion( "UDP-galactose-diacylglyceride galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "MGDG synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "UDP-sulphoquinovose:DAG sulphoquinovosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-1224"^^xsd:string) "Catalysis of the reaction: UDP-sulfoquinovose + 1,2-diacylglycerol = sulfoquinovosyldiacylglycerol + UDP."^^xsd:string) AnnotationAssertion(rdfs:label "UDP-sulfoquinovose:DAG sulfoquinovosyltransferase activity"^^xsd:string) AnnotationAssertion( "sulfolipid synthase"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.100"^^xsd:string) "5-methylthioribose kinase (phosphorylating)"^^xsd:string) AnnotationAssertion( "5-methylthioribose kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.100"^^xsd:string) "ATP:S5-methyl-5-thio-D-ribose 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.100"^^xsd:string) "MTR kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.100"^^xsd:string) "methylthioribose kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.100"^^xsd:string) Annotation( "RHEA:22315"^^xsd:string) "Catalysis of the reaction: S-methyl-5-thio-D-ribose + ATP = S-methyl-5-thio-alpha-D-ribose 1-phosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.100"^^xsd:string) "ATP:S-methyl-5-thio-D-ribose 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "S-methyl-5-thioribose kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "5-methylthioribose-1-phosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.23"^^xsd:string) "methylthioribose 1-phosphate isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "S-methyl-5-thioribose-1-phosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.23"^^xsd:string) "S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.23"^^xsd:string) "S-methyl-5-thio-D-ribose-1-phosphate aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.23"^^xsd:string) "S-methyl-5-thio-alpha-D-ribose-1-phosphate aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.23"^^xsd:string) "MTR-1-P isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.23"^^xsd:string) "S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate ketol-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.23"^^xsd:string) "5-methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.23"^^xsd:string) "1-PMTR isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.23"^^xsd:string) Annotation( "RHEA:19992"^^xsd:string) "Catalysis of the reaction: S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.23"^^xsd:string) "1-phospho-5'-S-methylthioribose isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.14"^^xsd:string) "sucrosephosphate-UDP glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.14"^^xsd:string) "UDP-glucose:D-fructose-6-phosphate 2-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sucrose-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.14"^^xsd:string) "uridine diphosphoglucose-fructose phosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.14"^^xsd:string) "UDP-glucose-fructose-phosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.14"^^xsd:string) "sucrose phosphate-uridine diphosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.14"^^xsd:string) "sucrose 6-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.14"^^xsd:string) "UDPglucose-fructose-phosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.14"^^xsd:string) "UDPglucose:D-fructose-6-phosphate 2-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.14"^^xsd:string) "SPS"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.14"^^xsd:string) "Catalysis of the reaction: UDP-glucose + D-fructose 6-phosphate = UDP + sucrose 6-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.14"^^xsd:string) "sucrose phosphate synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "xylosylprotein 4-beta-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.133"^^xsd:string) "Catalysis of the reaction: UDP-galactose + O-beta-D-xylosylprotein = UDP + 4-beta-D-galactosyl-O-beta-D-xylosylprotein."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.133"^^xsd:string) "UDP-galactose:O-beta-D-xylosylprotein 4-beta-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.133"^^xsd:string) "UDP-D-galactose:D-xylose galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.133"^^xsd:string) "uridine diphosphogalactose-xylose galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "UDP-galactose:xylose galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.133"^^xsd:string) "UDPgalactose:O-beta-D-xylosylprotein 4-beta-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.133"^^xsd:string) "galactosyltransferase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.133"^^xsd:string) "UDP-D-galactose:xylose galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.9"^^xsd:string) "xylitol dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-xylulose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.9"^^xsd:string) Annotation( "RHEA:20436"^^xsd:string) "Catalysis of the reaction: NAD(+) + xylitol = D-xylulose + H(+) + NADH."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of a glucosyl group to an acceptor molecule, typically another carbohydrate or a lipid."^^xsd:string) AnnotationAssertion(rdfs:label "glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.1"^^xsd:string) "Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D glycerate; this reaction does not require the cofactor 2,3-bisphosphoglycerate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.1"^^xsd:string) "PGAM-i"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.2.1"^^xsd:string) "glycerate phosphomutase (diphosphoglycerate cofactor) activity"^^xsd:string) AnnotationAssertion(rdfs:label "2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.1"^^xsd:string) "Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate; this reaction requires the cofactor 2,3-bisphosphoglycerate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.1"^^xsd:string) "PGAM-d"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.8"^^xsd:string) "histamine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.8"^^xsd:string) "S-adenosyl-L-methionine:histamine N-tele-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "histamine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.8"^^xsd:string) "imidazolemethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.8"^^xsd:string) "histamine-methylating enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.8"^^xsd:string) "histamine 1-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.8"^^xsd:string) "S-adenosylmethionine-histamine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.8"^^xsd:string) Annotation( "RHEA:19304"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + histamine = N(tau)-methylhistamine + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "trans-aconitate 3-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.145"^^xsd:string) "S-adenosyl-L-methionine:(E)-prop-1-ene-1,2,3-tricarboxylate 3'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.145"^^xsd:string) Annotation( "RHEA:22203"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + trans-aconitate = (E)-2-(methoxycarbonylmethyl)but-2-enedioate + S-adenosyl-L-homocysteine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.83"^^xsd:string) "D-malic enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.83"^^xsd:string) "D-malate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.83"^^xsd:string) "bifunctional L(+)-tartrate dehydrogenase-D(+)-malate (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.83"^^xsd:string) "(R)-malate:NAD+ oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.83"^^xsd:string) Annotation( "RHEA:18368"^^xsd:string) "Catalysis of the reaction: (R)-malate + NAD(+) = CO(2) + NADH + pyruvate."^^xsd:string) AnnotationAssertion(rdfs:label "D-malate dehydrogenase (decarboxylating) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.82"^^xsd:string) "malate NADP dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.82"^^xsd:string) "Catalysis of the reaction: (S)-malate + NADP+ = oxaloacetate + NADPH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "malate dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.82"^^xsd:string) "malic dehydrogenase (nicotinamide adenine dinucleotide phosphate)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.82"^^xsd:string) Annotation( "KEGG:R00343"^^xsd:string) "(S)-malate:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.82"^^xsd:string) "NADP-malate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.82"^^xsd:string) "NADP malate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.82"^^xsd:string) "NADP-linked malate dehydrogenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.72"^^xsd:string) "Catalysis of the deacetylation of xylans and xylo-oligosaccharides."^^xsd:string) AnnotationAssertion(rdfs:label "acetylxylan esterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.55"^^xsd:string) "arabinofuranosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.55"^^xsd:string) "alpha-L-arabinofuranoside arabinofuranohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.55"^^xsd:string) "alpha-L-arabinanase activity"^^xsd:string) AnnotationAssertion( "alpha-L-arabinofuranosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.55"^^xsd:string) "alpha-L-arabinofuranoside hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.55"^^xsd:string) "Catalysis of the hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.55"^^xsd:string) "L-arabinosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.55"^^xsd:string) "alpha-L-arabinosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-N-arabinofuranosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.55"^^xsd:string) "alpha-arabinofuranosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.55"^^xsd:string) "alpha-arabinosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.55"^^xsd:string) "arabinosidase activity"^^xsd:string) AnnotationAssertion( "polysaccharide alpha-L-arabinofuranosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "endo-(1,6)-beta-D-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.75"^^xsd:string) "1,6-beta-D-glucan glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.75"^^xsd:string) "endo-beta-1,6-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.75"^^xsd:string) "beta-1,6-glucan 6-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.75"^^xsd:string) "endo-1,6-beta-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.75"^^xsd:string) "Catalysis of the random hydrolysis of (1->6) linkages in (1->6)-beta-D-glucans."^^xsd:string) AnnotationAssertion(rdfs:label "glucan endo-1,6-beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.75"^^xsd:string) "endo-(1->6)-beta-D-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.75"^^xsd:string) "beta-1->6-glucan hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.75"^^xsd:string) "beta-1,6-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.75"^^xsd:string) "endo-1,6-beta-D-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.75"^^xsd:string) "beta-1,6-glucanase-pustulanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.75"^^xsd:string) "beta-1,6-glucan hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.99"^^xsd:string) "endo-1,5-alpha-L-arabinanase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arabinan endo-1,5-alpha-L-arabinosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.99"^^xsd:string) "Catalysis of the endohydrolysis of (1->5)-alpha-arabinofuranosidic linkages in (1->5) arabinans."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.99"^^xsd:string) "1,5-alpha-L-arabinan 1,5-alpha-L-arabinanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.99"^^xsd:string) "endo-arabanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.99"^^xsd:string) "endo-alpha-1,5-arabanase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.139"^^xsd:string) "alpha-D-glucosiduronate glucuronohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.139"^^xsd:string) "alpha-glucosiduronase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-glucuronidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.139"^^xsd:string) "Catalysis of the reaction: an alpha-D-glucuronoside + H2O = an alcohol + D-glucuronate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.4"^^xsd:string) "microcid"^^xsd:string) AnnotationAssertion( "beta-D-glucose oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.4"^^xsd:string) "glucose oxyhydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.4"^^xsd:string) "beta-D-glucose:oxygen 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.4"^^xsd:string) "beta-D-glucose:oxygen 1-oxido-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.4"^^xsd:string) "beta-D-glucose:quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.4"^^xsd:string) "D-glucose-1-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.4"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: beta-D-glucose + O2 = D-glucono-1,5-lactone + H2O2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.4"^^xsd:string) "D-glucose oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.4"^^xsd:string) "GOD activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.4"^^xsd:string) "deoxin-1"^^xsd:string) AnnotationAssertion(rdfs:label "glucose oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.4"^^xsd:string) "penatin"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.4"^^xsd:string) "glucose aerodehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.4"^^xsd:string) "corylophyline"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:METHANOL-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: O2 + methanol = H2O2 + formaldehyde."^^xsd:string) AnnotationAssertion(rdfs:label "methanol oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.2"^^xsd:string) "oxalate carboxy-lyase (formate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "oxalate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.2"^^xsd:string) Annotation( "RHEA:16512"^^xsd:string) "Catalysis of the reaction: H(+) + oxalate = CO(2) + formate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.2"^^xsd:string) "oxalate carboxy-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-dehydroshikimate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.-"^^xsd:string) Annotation( "MetaCyc:DHSHIKIMATE-DEHYDRO-RXN"^^xsd:string) "Catalysis of the reaction: 3-dehydroshikimate = 3,4-dihydroxybenzoate + H2O. 3,4-dihydroxybenzoate is also known as protocatechuate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DOPA dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11711071"^^xsd:string) "Catalysis of the 4,5-ring opening reaction: 3,4-dihydroxyphenylalanine + O2 = 4,5-seco-DOPA. 4,5-seco-DOPA spontaneously recyclizes to form betalamic acid."^^xsd:string) AnnotationAssertion( "dihydroxyphenylalanine dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aphidicolan-16 beta-ol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.42"^^xsd:string) Annotation( "PMID:12149019"^^xsd:string) "Catalysis of the reaction: 9-alpha-copalyl diphosphate + H2O = aphidicolan-16-beta-ol + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.42"^^xsd:string) "9-alpha-copalyl-diphosphate diphosphate-lyase (aphidicolan-16-beta-ol-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "isoamyl alcohol oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-methylbutanol:NAD(P) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.265"^^xsd:string) "Catalysis of the reaction: 3-methylbutanol + NAD(P)+ = 3-methylbutanal + NAD(P)H + H+. 3-methylbutanal is also known as isovaleraldehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.265"^^xsd:string) "3-methylbutanal reductase [NAD(P)] activity"^^xsd:string) AnnotationAssertion( "3-methylbutyraldehyde reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glyoxal oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.-"^^xsd:string) Annotation( "PMID:11733005"^^xsd:string) "Catalysis of the reaction: glyoxal + O2 + H2O = glyoxalate + H2O2."^^xsd:string) AnnotationAssertion( "GLOX"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.109"^^xsd:string) Annotation( "RHEA:15552"^^xsd:string) "Catalysis of the reaction: S-methyl-5-thio-D-ribulose 1-phosphate = 5-(methylthio)-2,3-dioxopentyl phosphate + H(2)O."^^xsd:string) AnnotationAssertion( "methylthioribulose-1-phosphate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:R145-RXN"^^xsd:string) "5-methylthioribulose-1-phosphate 4-dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.109"^^xsd:string) "S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase [5-(methylthio)-2,3-dioxopentyl-phosphate-forming]"^^xsd:string) AnnotationAssertion(rdfs:label "methylthioribulose 1-phosphate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.109"^^xsd:string) "1-PMT-ribulose dehydratase activity"^^xsd:string) AnnotationAssertion( "S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase[5-(methylthio)-2,3-dioxopentyl-phosphate-forming]"^^xsd:string) AnnotationAssertion( "S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:R15-RXN"^^xsd:string) "Catalysis of the reaction: 2-keto-4-methylthiobutyrate + aspartate = methionine + oxaloacetate."^^xsd:string) AnnotationAssertion(rdfs:label "aspartate-2-keto-4-methylthiobutyrate transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-9494"^^xsd:string) Annotation( "PMID:8784203"^^xsd:string) "Catalysis of the reaction: versiconal = versicolorin B + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "versicolorin B synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11640988"^^xsd:string) "Catalysis of the hydrolysis of lactone rings (intramolecular cyclic esters) to produce a hydroxyl group and a carboxyl group."^^xsd:string) AnnotationAssertion(rdfs:label "lactonohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycuronidase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10441389"^^xsd:string) Annotation( "PMID:12044176"^^xsd:string) "Catalysis of the hydrolysis of glucuronosides, yielding free glucuronic acid."^^xsd:string) AnnotationAssertion( "glucuronyl hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:10801485"^^xsd:string) "Catalysis of the removal of acetylesters (as acetate) from galacturonic acid residues in the backbone of rhamnogalacturonan."^^xsd:string) AnnotationAssertion(rdfs:label "rhamnogalacturonan acetylesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:8587995"^^xsd:string) Annotation( "PMID:8720076"^^xsd:string) "Catalysis of the cleavage of rhamnogalacturonan, generating oligosaccharides of the form alpha-D-us-galacturonic acid-(1,2)-alpha-L-rhamnose-(1,4)-alpha-D-galacturonate-(1,2)-L-rhamnose-(1,2)-alpha-L-rhamnose-p-(1,4)-alpha-D-galacturonic acid, terminating at the non-reducing end with a hex-4-enopyranosyluronic acid residue."^^xsd:string) AnnotationAssertion(Annotation( "PMID:8587995"^^xsd:string) "rhamnogalacturonase B activity"^^xsd:string) AnnotationAssertion(rdfs:label "rhamnogalacturonan alpha-L-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronide lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.20"^^xsd:string) "long-chain-alcohol:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.20"^^xsd:string) "long-chain fatty acid oxidase activity"^^xsd:string) AnnotationAssertion( "long-chain fatty alcohol oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "long-chain-alcohol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.20"^^xsd:string) "fatty alcohol:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.20"^^xsd:string) "Catalysis of the reaction: 2 long-chain alcohol + O2 = 2 long-chain aldehyde + 2 H2O."^^xsd:string) AnnotationAssertion( "fatty alcohol oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Rap GTPase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pg"^^xsd:string) "Rap GAP activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Increases the rate of GTP hydrolysis by a GTPase of the Rap family."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a cation or cations from the inside of the cell to the outside of the cell across a membrane."^^xsd:string) AnnotationAssertion( "cation efflux permease activity"^^xsd:string) AnnotationAssertion(rdfs:label "cation efflux transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "RNase N2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "RNase Sa"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "ribonuclease SA"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "guanyl-specific RNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "ribonuclease N1"^^xsd:string) AnnotationAssertion( "ribonuclease F1"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "ribonuclease U1"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "RNase N1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "guanyloribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "RNase G"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "RNase F1"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "ribonuclease PP1"^^xsd:string) AnnotationAssertion(rdfs:label "ribonuclease T1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "ribonuclease N3"^^xsd:string) AnnotationAssertion( "RNase T1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "binase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "ribonuclease C2"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "Aspergillus oryzae ribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "Catalysis of the endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate intermediates."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "ribonuclease guaninenucleotido-2'-transferase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "ribonuclease Ch"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.27.3"^^xsd:string) "RNase T1"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "polyamine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.11"^^xsd:string) "N1-acetylspermidine:oxygen oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.11"^^xsd:string) Annotation( "PMID:1567380"^^xsd:string) "Catalysis of the oxidative degradation or interconversion of polyamines."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.11"^^xsd:string) "1-N-acetylspermidine:oxygen oxidoreductase (deaminating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.10"^^xsd:string) "D-alpha-hydroxynitrile lyase activity"^^xsd:string) AnnotationAssertion( "hydroxynitrile lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mandelonitrile lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.10"^^xsd:string) "Catalysis of the reaction: mandelonitrile = cyanide + benzaldehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.10"^^xsd:string) "(R)-oxynitrilase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.10"^^xsd:string) "mandelonitrile benzaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.10"^^xsd:string) "mandelonitrile benzaldehyde-lyase (cyanide-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.10"^^xsd:string) "D-oxynitrilase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11884677"^^xsd:string) "Catalysis of the isomerization of poly-cis-carotenoids to all-trans-carotenoids."^^xsd:string) AnnotationAssertion(rdfs:label "carotenoid isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + solute(in) = solute(in) + sulfate(out), by a channel in a cell membrane whose opening is governed by the membrane potential."^^xsd:string) AnnotationAssertion( "voltage gated sulfate antiporter activity"^^xsd:string) AnnotationAssertion( "voltage-dependent sulfate antiporter activity"^^xsd:string) AnnotationAssertion( "voltage-sensitive sulphate antiporter activity"^^xsd:string) AnnotationAssertion( "prestin"^^xsd:string) AnnotationAssertion(rdfs:label "voltage-gated sulfate antiporter activity"^^xsd:string) AnnotationAssertion( "voltage-sensitive sulfate antiporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sphingolipid-translocating ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:12034738"^^xsd:string) "Catalysis of the movement of sphingolipids from one membrane face to the other ('flippase' activity), driven by the hydrolysis of ATP."^^xsd:string) AnnotationAssertion( "sphingolipid flippase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of sphingolipids into, out of or within a cell, or between cells. Sphingolipids are a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)."^^xsd:string) AnnotationAssertion(rdfs:label "sphingolipid transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with sphingolipids, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid)."^^xsd:string) AnnotationAssertion(rdfs:label "sphingolipid binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "The action characteristic of a hormone that takes part in the digestion process."^^xsd:string) AnnotationAssertion( "secretin"^^xsd:string) AnnotationAssertion(rdfs:label "digestive hormone activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "galactoside 6-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12413479"^^xsd:string) "Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to a galactoside acceptor molecule, usually an N-glycan, to form an alpha(1,6)-fucosylated galactoside."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "KLRC4 receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "natural killer cell lectin-like receptor binding"^^xsd:string) AnnotationAssertion( "NKG2D receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a lectin-like natural killer cell receptor."^^xsd:string) AnnotationAssertion( "NK cell lectin-like receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:22908"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Interacting selectively and non-covalently with borate, the anion (BO3)3-."^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "boron binding"^^xsd:string) AnnotationAssertion(rdfs:label "borate binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "borate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "boron transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "efflux-type boron transporter"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12447444"^^xsd:string) "Catalysis of the transport of borate across a membrane against the concentration gradient."^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "efflux-type borate transporter"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cell surface receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "host cell surface receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:11511370"^^xsd:string) "Interacting selectively and non-covalently with a receptor on the host cell surface."^^xsd:string) AnnotationAssertion( "cell surface antigen activity, host-interacting"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a virion, either by binding to components of the capsid or the viral envelope."^^xsd:string) AnnotationAssertion(rdfs:label "virion binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "host cell extracellular matrix binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:7996163"^^xsd:string) "Interacting selectively and non-covalently with the extracellular matrix of a host cell."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone deacetylase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:10482575"^^xsd:string) "Stops, prevents or reduces the activity of histone deacetylase, which catalyzes of the removal of acetyl groups from histones, proteins complexed to DNA in chromatin and chromosomes."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "host cell surface binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the surface of a host cell."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0781718325"^^xsd:string) "Interacts with chemokine receptors to reduce the action of a chemokine."^^xsd:string) AnnotationAssertion(rdfs:label "chemokine receptor antagonist activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "aminodeoxychorismate synthase activity"^^xsd:string) AnnotationAssertion( "para-aminobenzoic acid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.85"^^xsd:string) "ADC synthase activity"^^xsd:string) AnnotationAssertion( "p-aminobenzoate synthetase"^^xsd:string) AnnotationAssertion( "para-aminobenzoic acid (PABA) synthase"^^xsd:string) AnnotationAssertion(rdfs:label "4-amino-4-deoxychorismate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.85"^^xsd:string) "chorismate:L-glutamine amido-ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.85"^^xsd:string) "PabB activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.85"^^xsd:string) Annotation( "RHEA:11675"^^xsd:string) "Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, releasing glutamate. The ammonia is used by the second activity which catalyzes the amination of chorismate to form 4-amino-4-deoxychorismate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:52255"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Interacting selectively and non-covalently with hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentin."^^xsd:string) AnnotationAssertion(rdfs:label "hydroxyapatite binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "hydroxylapatite binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces NAD or NADP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "ribulose-1,5-bisphosphate carboxylase/oxygenase activase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity"^^xsd:string) AnnotationAssertion( "rubisco activator"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10430961"^^xsd:string) Annotation( "PMID:10965036"^^xsd:string) Annotation( "PMID:2404515"^^xsd:string) "Increases the activity of rubisco by the removal of otherwise inhibitory sugar phosphates: RuBP, and in some plants, 2-carboxyarabinitol 1-phosphate."^^xsd:string) AnnotationAssertion( "rubisco activase activity"^^xsd:string) AnnotationAssertion( "ribulose-bisphosphate carboxylase activase activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "cadmium ion binding"^^xsd:string) AnnotationAssertion( "cadmium binding"^^xsd:string) AnnotationAssertion( "copper/cadmium binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with cadmium (Cd) ions."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-acetylgalactosamine binding"^^xsd:string) AnnotationAssertion( "N-acetylgalactosamine lectin"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:28800"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, the n-acetyl derivative of galactosamine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "metal binding"^^xsd:string) AnnotationAssertion(rdfs:label "metal ion binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with any metal ion."^^xsd:string) AnnotationAssertion( "heavy metal binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "low affinity metal ion uptake transporter activity"^^xsd:string) AnnotationAssertion( "high affinity metal ion uptake transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of metal ions from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "metal ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "heavy metal ion:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "heavy metal ion transporter activity"^^xsd:string) AnnotationAssertion( "heavy metal ion porter activity"^^xsd:string) AnnotationAssertion( "heavy metal-exporting ATPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "GPI-linked ephrin"^^xsd:string) AnnotationAssertion(rdfs:label "ephrin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with an ephrin receptor."^^xsd:string) AnnotationAssertion( "Eph receptor binding"^^xsd:string) AnnotationAssertion( "transmembrane ephrin"^^xsd:string) AnnotationAssertion( "ephrin"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "blue-sensitive opsin"^^xsd:string) AnnotationAssertion( "green-sensitive opsin"^^xsd:string) AnnotationAssertion( "red-sensitive opsin"^^xsd:string) AnnotationAssertion( "long-wave-sensitive opsin"^^xsd:string) AnnotationAssertion( "short-wave-sensitive opsin"^^xsd:string) AnnotationAssertion(rdfs:label "3,4-didehydroretinal binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with 3,4-didehydroretinal, a form of retinal that plays a role in the visual process in freshwater fish and some amphibians analogous to that of all-trans retinal in other vertebrates. 3,4-didehydro-11-cis-retinal combines with an opsin to form cyanopsin (cone) or porphyropsin (rod)."^^xsd:string) AnnotationAssertion( "violet-sensitive opsin"^^xsd:string) AnnotationAssertion( "UV-sensitive opsin"^^xsd:string) AnnotationAssertion( "opsin"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "nucleoside-triphosphate-adenylate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.10"^^xsd:string) "nucleoside-triphosphate:AMP phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nucleoside triphosphate adenylate kinase activity"^^xsd:string) AnnotationAssertion( "nucleoside triphosphate-adenosine monophosphate transphosphorylase activity"^^xsd:string) AnnotationAssertion( "guanosine triphosphate-adenylate kinase"^^xsd:string) AnnotationAssertion( "GTP:AMP phosphotransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.10"^^xsd:string) "isozyme 3 of adenylate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.10"^^xsd:string) "Catalysis of the reaction: nucleoside triphosphate + AMP = nucleoside diphosphate + ADP."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcium oxalate binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0721662544"^^xsd:string) "Interacting selectively and non-covalently with calcium oxalate, CaC2O4, a salt of oxalic acid. In animals, it may be excreted in urine or retained in the form of urinary calculi."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phytoene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:12641468"^^xsd:string) "Catalysis of the reaction: prephytoene pyrophosphate = phytoene + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tetrapyrrole binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:26932"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position."^^xsd:string) AnnotationAssertion( "porphyrin binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pectinesterase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:10880981"^^xsd:string) "Stops, prevents or reduces the activity of any pectinesterase enzyme."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "heavy metal chelation"^^xsd:string) AnnotationAssertion( "metal chelation"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) Annotation( "ISBN:0716731363"^^xsd:string) "The formation of bonds from two or more atoms within the same ligand to a metal atom in complexes in which the metal is part of a ring."^^xsd:string) AnnotationAssertion(rdfs:label "metal chelating activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor), with the acyl group being converted into alkyl on transfer."^^xsd:string) AnnotationAssertion(rdfs:label "transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver."^^xsd:string) AnnotationAssertion(rdfs:label "transition metal ion binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "transition metal ion transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of transition metal ions from one side of a membrane to the other. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.25"^^xsd:string) "CitG activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.25"^^xsd:string) "ATP:3-dephospho-CoA 5''-triphosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.25"^^xsd:string) "Catalysis of the reaction: ATP + 3-dephospho-CoA = 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA + adenine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.25"^^xsd:string) "2'-(5''-triphosphoribosyl)-3-dephospho-CoA synthase activity"^^xsd:string) AnnotationAssertion( "ATP:dephospho-CoA 5-triphosphoribosyl transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "triphosphoribosyl-dephospho-CoA synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a pyruvyl (oxopropanoyl) group from one compound to another."^^xsd:string) AnnotationAssertion(rdfs:label "pyruvyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "alpha-1,3-fucosyltransferase activity"^^xsd:string) AnnotationAssertion( "alpha(1,3)-fucosyltransferase activity"^^xsd:string) AnnotationAssertion( "alpha-(1,3)-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-(1->3)-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->6) linkage."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "alpha(1,6)-fucosyltransferase activity"^^xsd:string) AnnotationAssertion( "alpha-(1,6)-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-(1->6)-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->6) linkage."^^xsd:string) AnnotationAssertion( "alpha-1,6-fucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.221"^^xsd:string) "Catalysis of the transfer of an alpha-L-fucosyl residue from GDP- beta-L-fucose to the serine hydroxy group of a protein acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.221"^^xsd:string) "GDP-L-fucose:polypeptide fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.221"^^xsd:string) "GDP-fucose:polypeptide fucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "peptide-O-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.221"^^xsd:string) "GDP-beta-L-fucose:polypeptide O-alpha-L-fucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.221"^^xsd:string) "GDP-fucose protein O-fucosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "endoplasmic reticulum retention sequence binding"^^xsd:string) AnnotationAssertion(rdfs:label "ER retention sequence binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with an endoplasmic reticulum (ER) retention sequence, a specific peptide sequence that ensures a protein is retained within the ER."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sodium-translocating F-type ATPase activity"^^xsd:string) AnnotationAssertion( "sodium-transporting two-sector ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.15"^^xsd:string) Annotation( "TC:3.A.2.1.2"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ADP + phosphate + Na+(out) = ATP + H2O + Na+(in), by a rotational mechanism."^^xsd:string) AnnotationAssertion(rdfs:label "sodium-transporting ATP synthase activity, rotational mechanism"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "hydrogen ion translocating F-type ATPase activity"^^xsd:string) AnnotationAssertion( "hydrogen ion transporting two-sector ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) Annotation( "TC:3.A.2.1.1"^^xsd:string) "Catalysis of the transfer of protons from one side of a membrane to the other according to the reaction: ADP + H2O + phosphate + H+(in) = ATP + H+(out), by a rotational mechanism."^^xsd:string) AnnotationAssertion(rdfs:label "proton-transporting ATP synthase activity, rotational mechanism"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) "H+-transporting ATP synthase activity"^^xsd:string) AnnotationAssertion( "hydrogen ion transporting ATP synthase activity, rotational mechanism"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.153"^^xsd:string) "ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase activity"^^xsd:string) AnnotationAssertion( "phosphatidylinositol 3-kinase, class I, catalyst activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol-4,5-bisphosphate 3-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.153"^^xsd:string) Annotation( "RHEA:21295"^^xsd:string) "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion( "phosphatidylinositol 3-kinase activity, class II"^^xsd:string) AnnotationAssertion( "phosphatidylinositol 3-kinase activity, class I"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.153"^^xsd:string) "type I phosphoinositide 3-kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "1-phosphatidylinositol 3-kinase regulator activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-phosphatidylinositol-3-kinase regulator activity"^^xsd:string) AnnotationAssertion( "phosphatidylinositol 3-kinase, class I, regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Modulates the activity of the enzyme 1-phosphatidylinositol-3-kinase activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "deoxyadenosine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.4"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: deoxyadenosine + H2O = deoxyinosine + NH3."^^xsd:string) AnnotationAssertion( "deoxyadenosine deaminase reaction"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "azetidine-2-carboxylic acid acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12761200"^^xsd:string) "Catalysis of the reaction: L-azetidine-2-carboxylic acid + acetyl-CoA = CoA-SH + N-acetyl azetidine-2-carboxylic acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of carboxylic acids from one side of the membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)."^^xsd:string) AnnotationAssertion(rdfs:label "carboxylic acid transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "proton-transporting ATPase activity, rotational mechanism"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) "H+-transporting two-sector ATPase"^^xsd:string) AnnotationAssertion( "hydrogen ion transporting ATPase activity, rotational mechanism"^^xsd:string) AnnotationAssertion( "hydrogen ion transporting two-sector ATPase activity"^^xsd:string) AnnotationAssertion( "hydrogen ion translocating V-type ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) "F(o)F(1)-ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) "bacterial Ca2+/Mg2+ ATPase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) "F0F1-ATPase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) "F(0)F(1)-ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) "H(+)-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) "FoF1-ATPase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) "coupling factors (Fo, F1 and CF1)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) "H+-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) "F(1)-ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) "F1-ATPase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) "ATP phosphohydrolase (H+-transporting) activity"^^xsd:string) AnnotationAssertion( "hydrogen ion translocating A-type ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) "H(+)-transporting ATP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) "ATP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) "Catalysis of the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) "chloroplast ATPase activity"^^xsd:string) AnnotationAssertion( "hydrogen ion translocating F-type ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.14"^^xsd:string) "mitochondrial ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.3.15"^^xsd:string) "vacuolar-type Na+-ATPase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.15"^^xsd:string) "Na(+)-transporting two-sector ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.15"^^xsd:string) "Na+-translocating ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.15"^^xsd:string) "ATP phosphohydrolase (Na+-transporting) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.15"^^xsd:string) "Na+-transporting two-sector ATPase"^^xsd:string) AnnotationAssertion( "sodium-translocating V-type ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.15"^^xsd:string) "Na+-translocating F1Fo-ATPase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.15"^^xsd:string) "Na(+)-translocating ATPase activity"^^xsd:string) AnnotationAssertion( "sodium-translocating F-type ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.145"^^xsd:string) "ATP synthase, sodium ion specific activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.15"^^xsd:string) "vacuolar-type Na+-translocating ATPase"^^xsd:string) AnnotationAssertion(rdfs:label "sodium-transporting ATPase activity, rotational mechanism"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.3.15"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out), by a rotational mechanism."^^xsd:string) AnnotationAssertion( "sodium transporting ATPase activity, rotational mechanism"^^xsd:string) AnnotationAssertion( "sodium-transporting two-sector ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3'-phosphoadenosine 5'-phosphosulphate transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the transfer of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "adenosine 3'-phosphate 5'-phosphosulfate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "PAPS transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a retinoid X receptor."^^xsd:string) AnnotationAssertion(rdfs:label "retinoid X receptor binding"^^xsd:string) AnnotationAssertion( "RXR binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a thyroid hormone receptor."^^xsd:string) AnnotationAssertion(rdfs:label "thyroid hormone receptor binding"^^xsd:string) AnnotationAssertion( "ligand-dependent thyroid hormone receptor interactor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.17"^^xsd:string) Annotation( "EC:3.5.1.98"^^xsd:string) Annotation( "RHEA:24551"^^xsd:string) "Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein."^^xsd:string) AnnotationAssertion(rdfs:label "NAD-dependent histone deacetylase activity (H3-K9 specific)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NAD-dependent histone deacetylase activity (H4-K16 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.17"^^xsd:string) Annotation( "EC:3.5.1.98"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) Annotation( "RHEA:24551"^^xsd:string) "Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone acetyltransferase activity (H4-K16 specific)"^^xsd:string) AnnotationAssertion( "histone lysine acetyltransferase activity (H4-K16 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.48"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 16) = CoA + histone H4 N6-acetyl-L-lysine (position 16). This reaction represents the addition of an acetyl group to the lysine at position 16 of histone H4."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 9) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 9). This reaction is the addition of a methyl group onto lysine at position 9 of the histone H3 protein."^^xsd:string) AnnotationAssertion( "histone lysine N-methyltransferase activity (H3-K9 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone methyltransferase activity (H3-K9 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histone methylase activity (H3-K9 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 36) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 36). This reaction is the addition of a methyl group onto lysine at position 36 of the histone H3 protein."^^xsd:string) AnnotationAssertion(rdfs:label "histone methyltransferase activity (H3-K36 specific)"^^xsd:string) AnnotationAssertion( "histone lysine N-methyltransferase activity (H3-K36 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histone methylase activity (H3-K36 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 27) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 27). This reaction is the addition of a methyl group onto lysine at position 27 of the histone H3 protein."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histone methylase activity (H3-K27 specific)"^^xsd:string) AnnotationAssertion( "histone lysine N-methyltransferase activity (H3-K27 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone methyltransferase activity (H3-K27 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11133832"^^xsd:string) "Interacting selectively and non-covalently with TAP protein, transporter associated with antigen processing protein. TAP protein is a heterodimeric peptide transporter consisting of the subunits TAP1 and TAP2."^^xsd:string) AnnotationAssertion(rdfs:label "TAP binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "TAP1 binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11133832"^^xsd:string) "Interacting selectively and non-covalently with the TAP1 subunit of TAP (transporter associated with antigen processing) protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "TAP2 binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11133832"^^xsd:string) "Interacting selectively and non-covalently with the TAP2 subunit of TAP (transporter associated with antigen processing) protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tapasin binding"^^xsd:string) AnnotationAssertion(Annotation( "HGNC:11566"^^xsd:string) "TAP binding protein binding"^^xsd:string) AnnotationAssertion(Annotation( "HGNC:11566"^^xsd:string) "TAPBP binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12594855"^^xsd:string) "Interacting selectively and non-covalently with tapasin, a member of the MHC class I loading complex which bridges the TAP peptide transporter to class I molecules."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:12130631"^^xsd:string) Annotation( "PMID:12130651"^^xsd:string) "Catalysis of the transfer of N-acetylglucosamine (GlcNAc) in a beta-1,3 linkage to the mannose(beta-1,4)Glc disaccharide core of glycolipids."^^xsd:string) AnnotationAssertion( "UDP-N-acetylglucosamine:beta-D-mannosyl-glycolipid beta-1,3-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein heterodimerization activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein dimerization activity"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:12511570"^^xsd:string) "Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-D-glucuronic acid to N-acetyllactosamine (galactosyl beta-1,4-N-acetylglucosamine)."^^xsd:string) AnnotationAssertion(rdfs:label "N-acetyllactosamine beta-1,3-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion( "galactosyl beta-1,4 N-acetylglucosamine beta-1,3 glucuronosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "asioloorosomucoid beta-1,3-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:12511570"^^xsd:string) "Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to asioloorosomucoid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:12511570"^^xsd:string) "Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to the disaccharide galactosyl beta-1,3 N-acetylgalactosamine, a common component of glycoproteins and glycolipids."^^xsd:string) AnnotationAssertion(rdfs:label "galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-hydroxyarylamine O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.118"^^xsd:string) "N-hydroxy-2-aminofluorene-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.118"^^xsd:string) Annotation( "MetaCyc:2.3.1.118-RXN"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + an N-hydroxyarylamine = CoA + an N-acetoxyarylamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.118"^^xsd:string) "arylhydroxamate N,O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.118"^^xsd:string) "acetyl-CoA:N-hydroxyarylamine O-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y."^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is oxygen."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on hydrogen as donor, with a quinone or similar compound as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces quinone or similar compound."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen reduces a known acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP, or a quinone or similar compound."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on hydrogen as donor, with other known acceptors"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and the latter donor is dehydrogenated."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NADH or NADPH as one donor, and the other dehydrogenated"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a flavin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(S)-usnate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.199"^^xsd:string) "reduced-(S)-usnate:NAD+ oxidoreductase (ether-bond-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.199"^^xsd:string) "L-usnic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.199"^^xsd:string) Annotation( "RHEA:21879"^^xsd:string) "Catalysis of the reaction: (6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methylcyclohexa-2,4-dien-1-one + NAD(+) = (S)-usnate + 2 H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.126"^^xsd:string) Annotation( "RHEA:15112"^^xsd:string) "Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + NADP(+) = (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + H(+) + NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.126"^^xsd:string) "2-keto-3-deoxy-D-gluconate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.126"^^xsd:string) "2-dehydro-3-deoxy-D-gluconate:NADP+ 6-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.127"^^xsd:string) "2-keto-3-deoxygluconate 5-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.127"^^xsd:string) "2-keto-3-deoxygluconate (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.127"^^xsd:string) "2-keto-3-deoxy-D-gluconate (3-deoxy-D-glycero-2,5-hexodiulosonic acid) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.127"^^xsd:string) "2-dehydro-3-deoxy-D-gluconate:NAD+ 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.127"^^xsd:string) "2-keto-3-deoxygluconate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.127"^^xsd:string) Annotation( "MetaCyc:1.1.1.127-RXN"^^xsd:string) "Catalysis of the reaction: NAD+ + 2-dehydro-3-deoxy-D-gluconate = NADH + (4S)-4,6-dihydroxy-2,5-dioxohexanoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-arabinitol 2-dehydrogenase (ribulose forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.13"^^xsd:string) Annotation( "RHEA:21359"^^xsd:string) "Catalysis of the reaction: L-arabinitol + NAD(+) = L-ribulose + H(+) + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "L-arabinitol 2-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dTDP-6-deoxy-L-talose 4-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.134"^^xsd:string) Annotation( "RHEA:23651"^^xsd:string) "Catalysis of the reaction: dTDP-6-deoxy-L-talose + NADP(+) = dTDP-4-dehydro-6-deoxy-L-mannose + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.134"^^xsd:string) "thymidine diphospho-6-deoxy-L-talose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.134"^^xsd:string) "TDP-6-deoxy-L-talose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.134"^^xsd:string) "dTDP-6-deoxy-L-talose dehydrogenase (4-reductase)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.134"^^xsd:string) "dTDP-6-deoxy-L-talose:NADP+ 4-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.136"^^xsd:string) "uridine diphosphoacetylglucosamine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.136"^^xsd:string) "UDP-GLcNAc dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.136"^^xsd:string) "UDP-N-acetyl-D-glucosamine:NAD+ 6-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-N-acetylglucosamine 6-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.136"^^xsd:string) Annotation( "RHEA:13328"^^xsd:string) "Catalysis of the reaction: H(2)O + 2 NAD(+) + UDP-N-acetyl-alpha-D-glucosamine = 3 H(+) + 2 NADH + UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.136"^^xsd:string) "UDPacetylglucosamine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.136"^^xsd:string) "UDP-2-acetamido-2-deoxy-D-glucose:NAD oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.147"^^xsd:string) "16alpha-hydroxy steroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.147"^^xsd:string) "16alpha-hydroxysteroid:NAD(P)+ 16-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.147"^^xsd:string) "16alpha-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.147"^^xsd:string) Annotation( "MetaCyc:1.1.1.147-RXN"^^xsd:string) "Catalysis of the reaction: NADP+ + 16-alpha-hydroxysteroid = NADPH + H+ + 16-oxosteroid."^^xsd:string) AnnotationAssertion(rdfs:label "16-alpha-hydroxysteroid dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.149"^^xsd:string) "20alpha-hydroxy steroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.149"^^xsd:string) "20alpha-HSDH"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.149"^^xsd:string) "20alpha-hydroxysteroid dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.149"^^xsd:string) Annotation( "MetaCyc:1.1.1.149-RXN"^^xsd:string) "Catalysis of the reaction: NAD(P)+ + 17-alpha,20-alpha-dihydroxypregn-4-en-3-one = NAD(P)H + H+ + 17-alpha-hydroxyprogesterone."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.149"^^xsd:string) "20alpha-hydroxysteroid:NAD(P)+ 20-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.149"^^xsd:string) "20alpha-HSD"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.50"^^xsd:string) "21-hydroxysteroid dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.150"^^xsd:string) "21-hydroxysteroid:NAD+ 21-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pregnan-21-ol dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.150"^^xsd:string) Annotation( "RHEA:11451"^^xsd:string) "Catalysis of the reaction: NAD(+) + pregnan-21-ol = H(+) + NADH + pregnan-21-al."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pregnan-21-ol dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.151"^^xsd:string) "21-hydroxy steroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.151"^^xsd:string) "21-hydroxysteroid:NADP+ 21-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.151"^^xsd:string) "NADP-21-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.151"^^xsd:string) "21-hydroxy steroid dehydrogenase (nicotinamide adenine dinucleotide phosphate) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.151"^^xsd:string) Annotation( "RHEA:23715"^^xsd:string) "Catalysis of the reaction: NADP(+) + pregnan-21-ol = H(+) + NADPH + pregnan-21-al."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.151"^^xsd:string) "21-hydroxysteroid dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.151"^^xsd:string) "21-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.152"^^xsd:string) "3alpha-hydroxy-5beta-steroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.152"^^xsd:string) "3alpha-hydroxy-5beta-steroid:NAD+ 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.152"^^xsd:string) "etiocholanolone 3alpha-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.152"^^xsd:string) "etiocholanolone 3-alpha-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.152"^^xsd:string) Annotation( "MetaCyc:1.1.1.152-RXN"^^xsd:string) "Catalysis of the reaction: NAD+ + 3-alpha-hydroxy-5-beta-androstane-17-one = NADH + H+ + 5-beta-androstane-3,17-dione."^^xsd:string) AnnotationAssertion(rdfs:label "3-alpha-hydroxy-5-beta-androstane-17-one 3-alpha-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.152"^^xsd:string) "3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.166"^^xsd:string) "dihydroxycyclohexanecarboxylate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.166"^^xsd:string) Annotation( "RHEA:10519"^^xsd:string) "Catalysis of the reaction: (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD(+) = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.166"^^xsd:string) "(-)t-3,t-4-dihydroxycyclohexane-c-1-carboxylate-NAD oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydroxycyclohexanecarboxylate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.166"^^xsd:string) "(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate:NAD+ 3-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.168"^^xsd:string) "2-ketopantoyl lactone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.168"^^xsd:string) "2-dehydropantoyl-lactone reductase (A-specific) activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-dehydropantolactone reductase (A-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.168"^^xsd:string) "ketopantoyl lactone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.168"^^xsd:string) "2-oxopantoyl lactone reductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.168"^^xsd:string) "(R)-pantolactone:NADP+ oxidoreductase (A-specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.168"^^xsd:string) Annotation( "MetaCyc:1.1.1.168-RXN"^^xsd:string) "Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.170"^^xsd:string) "3-beta-hydroxy-4-beta-methylcholestenoate dehydrogenase activity"^^xsd:string) AnnotationAssertion( "3-beta-hydroxy-4-alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.170"^^xsd:string) "sterol 4-alpha-carboxylic decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.170"^^xsd:string) "3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.170"^^xsd:string) "3-beta-hydroxy-4-beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.170"^^xsd:string) Annotation( "MetaCyc:1.1.1.170-RXN"^^xsd:string) "Catalysis of the reaction: NAD(P)+ + 3-beta-hydroxy-4-alpha-methyl-5-alpha-cholest-7-ene-4-beta-carboxylate = NAD(P)H + H+ + CO2 + 4-alpha-methyl-5-alpha-cholest-7-en-3-one."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.176"^^xsd:string) "12alpha-hydroxy steroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cholate 12-alpha dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.176"^^xsd:string) "NAD-dependent 12alpha-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.176"^^xsd:string) "12alpha-hydroxysteroid:NADP+ 12-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.176"^^xsd:string) "NADP-12alpha-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.176"^^xsd:string) "12alpha-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.176"^^xsd:string) Annotation( "RHEA:14132"^^xsd:string) "Catalysis of the reaction: cholate + NADP(+) = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.176"^^xsd:string) "12-alpha-hydroxysteroid dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.177"^^xsd:string) "sn-glycerol-3-phosphate:NADP+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.177"^^xsd:string) "glycerol phosphate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.177"^^xsd:string) "NADPH-dependent glycerin-3-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.177"^^xsd:string) "glycerin-3-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.177"^^xsd:string) "L-glycerol 3-phosphate:NADP oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.177"^^xsd:string) Annotation( "RHEA:19776"^^xsd:string) "Catalysis of the reaction: sn-glycerol 3-phosphate + NADP(+) = D-glyceraldehyde 3-phosphate + H(+) + NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "glycerol-3-phosphate 1-dehydrogenase [NADP+] activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.178"^^xsd:string) "2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.178"^^xsd:string) "2-methyl-3-hydroxy-butyryl CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.178"^^xsd:string) "(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.178"^^xsd:string) "2-methyl-3-hydroxybutyryl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.178"^^xsd:string) Annotation( "MetaCyc:1.1.1.178-RXN"^^xsd:string) "Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.181"^^xsd:string) "3beta-hydroxy-delta5-C27-steroid oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.181"^^xsd:string) Annotation( "MetaCyc:1.1.1.181-RXN"^^xsd:string) "Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one."^^xsd:string) AnnotationAssertion(rdfs:label "cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.181"^^xsd:string) "cholest-5-ene-3beta,7alpha-diol:NAD+ 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.181"^^xsd:string) "cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.181"^^xsd:string) "3-beta-hydroxy-Delta(5)-C(27)-steroid oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "prostaglandin-D(2) 11-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) Annotation( "MetaCyc:1.1.1.188-RXN"^^xsd:string) "Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "prostaglandin 11-ketoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "PGD(2) 11-ketoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "prostaglandin-F synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "prostaglandin D2-ketoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "prostaglandin-D2 11-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "prostaglandin-D2 ketoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "prostaglandin F synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 11-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "synthetase, prostaglandin F2alpha"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "NADPH-dependent prostaglandin D2 11-keto reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "prostaglandin-D(2) ketoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "prostaglandin-D2 11-ketoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "prostaglandin-F synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "prostaglandin-D(2) 11-ketoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "PGD2 11-ketoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "prostaglandin F synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "PGF2alpha synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "prostaglandin 11-keto reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "reductase, 15-hydroxy-11-oxoprostaglandin"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.188"^^xsd:string) "PGF synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "indole-3-acetaldehyde reductase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.190"^^xsd:string) "(indol-3-yl)ethanol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.190"^^xsd:string) "indoleacetaldehyde reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.190"^^xsd:string) Annotation( "RHEA:14876"^^xsd:string) "Catalysis of the reaction: indole-3-ethanol + NAD(+) = (indol-3-yl)acetaldehyde + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.190"^^xsd:string) "indole-3-ethanol:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.191"^^xsd:string) "(indol-3-yl)ethanol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.191"^^xsd:string) Annotation( "RHEA:17040"^^xsd:string) "Catalysis of the reaction: indole-3-ethanol + NADP(+) = (indol-3-yl)acetaldehyde + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.191"^^xsd:string) "indole-3-ethanol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "indole-3-acetaldehyde reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.191"^^xsd:string) "indoleacetaldehyde (reduced nicotinamide adenine dinucleotide phosphate) reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.196"^^xsd:string) "prostaglandin-D 15-dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.196"^^xsd:string) "prostaglandin-D 15-dehydrogenase (NADP)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.196"^^xsd:string) "NADP-PGD2 dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.196"^^xsd:string) "NADP-linked prostaglandin D2 dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.196"^^xsd:string) "NADP-specific 15-hydroxyprostaglandin dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.196"^^xsd:string) "15-hydroxy PGD2 dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.196"^^xsd:string) "NADP-dependent 15-hydroxyprostaglandin dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.196"^^xsd:string) "prostaglandin-D 15-dehydrogenase (NADP(+)) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.196"^^xsd:string) "NADP-linked 15-hydroxyprostaglandin dehydrogenase"^^xsd:string) AnnotationAssertion(rdfs:label "15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.196"^^xsd:string) "dehydrogenase, prostaglandin D2"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.196"^^xsd:string) "(5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.196"^^xsd:string) "15-hydroxyprostaglandin dehydrogenase (NADP)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.196"^^xsd:string) Annotation( "MetaCyc:1.1.1.196-RXN"^^xsd:string) "Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.196"^^xsd:string) "dehydrogenase, 15-hydroxyprostaglandin (nicotinamide adenine dinucleotide phosphate)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.196"^^xsd:string) "prostaglandin D2 dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.197"^^xsd:string) "NADP-specific 15-hydroxyprostaglandin dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.197"^^xsd:string) "NADP-dependent 15-hydroxyprostaglandin dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.197"^^xsd:string) "type II 15-hydroxyprostaglandin dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.197"^^xsd:string) "NADP-linked 15-hydroxyprostaglandin dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.197"^^xsd:string) Annotation( "RHEA:11639"^^xsd:string) "Catalysis of the reaction: NADP(+) + prostaglandin E(1) = 15-dehydro-prostaglandin E1 + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.197"^^xsd:string) "(13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NADP+ 15-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "15-hydroxyprostaglandin dehydrogenase (NADP+) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.201"^^xsd:string) Annotation( "MetaCyc:1.1.1.201-RXN"^^xsd:string) "Catalysis of the reaction: NADP+ + a 7-beta-hydroxysteroid = NADPH + H+ + a 7-oxosteroid."^^xsd:string) AnnotationAssertion(rdfs:label "7-beta-hydroxysteroid dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.201"^^xsd:string) "NADP-dependent 7beta-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.201"^^xsd:string) "7beta-hydroxysteroid dehydrogenase (NADP+)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.201"^^xsd:string) "NADP-dependent 7-beta-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.201"^^xsd:string) "7beta-hydroxysteroid:NADP+ 7-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.209"^^xsd:string) "3(or 17)-alpha-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.209"^^xsd:string) Annotation( "MetaCyc:1.1.1.209-RXN"^^xsd:string) "Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.209"^^xsd:string) "3(17)alpha-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.209"^^xsd:string) "3(or 17)alpha-hydroxysteroid:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.209"^^xsd:string) "3(or 17)alpha-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "androsterone dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.210"^^xsd:string) "3-beta-HSD activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.210"^^xsd:string) "3beta(or 20alpha)-hydroxysteroid:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.210"^^xsd:string) Annotation( "RHEA:16300"^^xsd:string) "Catalysis of the reaction: 5alpha-androstane-3beta,17beta-diol + NADP(+) = 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.210"^^xsd:string) "3beta,20alpha-hydroxysteroid oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.210"^^xsd:string) "dehydrogenase, 3beta,20alpha-hydroxy steroid"^^xsd:string) AnnotationAssertion(rdfs:label "5alpha-androstane-3beta,17beta-diol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.210"^^xsd:string) "3beta(or 20alpha)-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.210"^^xsd:string) "progesterone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.210"^^xsd:string) "3-beta(or 20-alpha)-hydroxysteroid dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3-oxoacyl-ACP reductase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.212"^^xsd:string) "3-oxoacyl-acyl-carrier-protein reductase (NADH)"^^xsd:string) AnnotationAssertion(rdfs:label "3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.212"^^xsd:string) Annotation( "MetaCyc:1.1.1.212-RXN"^^xsd:string) "Catalysis of the reaction: NAD+ + OH-acyl-[acyl-carrier protein] = NADH + H+ + B-ketoacyl-[acyl-carrier protein]."^^xsd:string) AnnotationAssertion( "3-oxoacyl-[acyl-carrier protein] reductase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.212"^^xsd:string) "3-oxoacyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.212"^^xsd:string) "(3R)-3-hydroxyacyl-acyl-carrier-protein:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.213"^^xsd:string) "3alpha-hydroxysteroid dehydrogenase (A-specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.213"^^xsd:string) "3-alpha-hydroxysteroid dehydrogenase (A-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.213"^^xsd:string) Annotation( "MetaCyc:1.1.1.213-RXN"^^xsd:string) "Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.213"^^xsd:string) "3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (A-specific)"^^xsd:string) AnnotationAssertion(rdfs:label "androsterone dehydrogenase (A-specific) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.217"^^xsd:string) Annotation( "RHEA:16408"^^xsd:string) "Catalysis of the reaction: benzyl (2R,3S)-2-methyl-3-hydroxybutanoate + NADP(+) = benzyl 2-methyl-3-oxobutanoate + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.217"^^xsd:string) "benzyl-(2R,3S)-2-methyl-3-hydroxybutanoate:NADP+ 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.217"^^xsd:string) "benzyl 2-methyl-3-hydroxybutyrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "benzyl-2-methyl-hydroxybutyrate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "6-pyruvoyltetrahydropterin 2'-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.220"^^xsd:string) "6-lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2'-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.220"^^xsd:string) "6-pyruvoyltetrahydropterin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.220"^^xsd:string) "6PPH4(2'-oxo) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.220"^^xsd:string) "pyruvoyl-tetrahydropterin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.220"^^xsd:string) Annotation( "MetaCyc:1.1.1.220-RXN"^^xsd:string) "Catalysis of the reaction: NADP+ + 6-lactoyl-5,6,7,8-tetrahydropterin = NADPH + H+ + 6-pyruvoyltetrahydropterin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.220"^^xsd:string) "6-pyruvoyl tetrahydropterin (2'-oxo)reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.220"^^xsd:string) "6-pyruvoyl-tetrahydropterin 2'-reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.222"^^xsd:string) "D-hydrogenase, D-aryllactate"^^xsd:string) AnnotationAssertion(rdfs:label "(R)-4-hydroxyphenyllactate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.222"^^xsd:string) "(R)-3-(4-hydroxyphenyl)lactate:NAD(P)+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.222"^^xsd:string) "(R)-aromatic lactate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.222"^^xsd:string) Annotation( "MetaCyc:1.1.1.222-RXN"^^xsd:string) "Catalysis of the reaction: NAD(P)+ + (R)-3-(4-hydroxyphenyl)lactate = NAD(P)H + H+ + 3-(4-hydroxyphenyl)pyruvate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.226"^^xsd:string) "trans-4-hydroxycyclohexanecarboxylate:NAD+ 4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.226"^^xsd:string) Annotation( "RHEA:17432"^^xsd:string) "Catalysis of the reaction: trans-4-hydroxycyclohexanecarboxylate + NAD(+) = 4-oxocyclohexanecarboxylate + H(+) + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxycyclohexanecarboxylate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.226"^^xsd:string) "trans-4-hydroxycyclohexanecarboxylate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "diethyl 2-methyl-3-oxosuccinate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.229"^^xsd:string) Annotation( "RHEA:21011"^^xsd:string) "Catalysis of the reaction: diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP(+) = diethyl 2-methyl-3-oxosuccinate + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.229"^^xsd:string) "diethyl-(2R,3R)-2-methyl-3-hydroxysuccinate:NADP+ 3-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.230"^^xsd:string) Annotation( "RHEA:20819"^^xsd:string) "Catalysis of the reaction: 3alpha-hydroxyglycyrrhetinate + NADP(+) = 3-oxoglycyrrhetinate + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.230"^^xsd:string) "3alpha-hydroxyglycyrrhetinate:NADP+ 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.230"^^xsd:string) "3alpha-hydroxyglycyrrhetinate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-alpha-hydroxyglycyrrhetinate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.231"^^xsd:string) "PG I2 dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.231"^^xsd:string) "NADP-linked 15-hydroxyprostaglandin (prostacyclin) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.231"^^xsd:string) "prostacyclin dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.231"^^xsd:string) "(5Z,13E)-(15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.231"^^xsd:string) "NADP+-dependent PGI2-specific 15-hydroxyprostaglandin dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.231"^^xsd:string) Annotation( "RHEA:21423"^^xsd:string) "Catalysis of the reaction: NADP(+) + prostaglandin I(2) = 15-dehydro-prostaglandin I(2) + H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.232"^^xsd:string) Annotation( "MetaCyc:1.1.1.232-RXN"^^xsd:string) "Catalysis of the reaction: NAD(P)+ + (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate = NAD(P)H + H+ + 15-oxo-5,8,11-cis-13-trans-icosatetraenoate."^^xsd:string) AnnotationAssertion(rdfs:label "15-hydroxyicosatetraenoate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.232"^^xsd:string) "15-hydroxyeicosatetraenoate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.232"^^xsd:string) "(15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate:NAD(P)+ 15-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.63"^^xsd:string) "17beta-hydroxysteroid:NAD+ 17-oxidoreductase activity"^^xsd:string) AnnotationAssertion( "testosterone 17b-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.63"^^xsd:string) "testosterone 17beta-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.239"^^xsd:string) "3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.239"^^xsd:string) "3alpha,17beta-hydroxy steroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.239"^^xsd:string) "3alpha(17beta)-HSD"^^xsd:string) AnnotationAssertion(rdfs:label "testosterone dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.63"^^xsd:string) "17beta-HSD"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.239"^^xsd:string) Annotation( "MetaCyc:1.1.1.239-RXN"^^xsd:string) "Catalysis of the reaction: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH."^^xsd:string) AnnotationAssertion( "testosterone 17-beta-dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.63"^^xsd:string) "17-ketoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.63"^^xsd:string) "17-beta-HSD activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.239"^^xsd:string) "3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.239"^^xsd:string) "3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "codeinone reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.247"^^xsd:string) Annotation( "RHEA:19212"^^xsd:string) "Catalysis of the reaction: codeine + NADP(+) = codeinone + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.247"^^xsd:string) "codeine:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "salutaridine reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.248"^^xsd:string) Annotation( "RHEA:10111"^^xsd:string) "Catalysis of the reaction: (7S)-salutaridinol + NADP(+) = H(+) + NADPH + salutaridine."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.248"^^xsd:string) "salutaridinol:NADP+ 7-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.250"^^xsd:string) "D-arabinitol:NAD+ 2-oxidoreductase (D-ribulose-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "D-arabinitol 2-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.250"^^xsd:string) "D-arabinitol 2-dehydrogenase (ribulose-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.250"^^xsd:string) Annotation( "RHEA:17392"^^xsd:string) "Catalysis of the reaction: D-arabinitol + NAD(+) = D-ribulose + H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.252"^^xsd:string) Annotation( "MetaCyc:1.1.1.252-RXN"^^xsd:string) "Catalysis of the reaction: NADP+ + scytalone = NADPH + H+ + 1,3,6,8-naphthalenetetrol."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.252"^^xsd:string) "T4HN reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tetrahydroxynaphthalene reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.252"^^xsd:string) "scytalone:NADP+ delta5-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.33"^^xsd:string) Annotation( "RHEA:19512"^^xsd:string) "Catalysis of the reaction: 5,6,7,8-tetrahydrobiopterin + 2 NADP(+) = biopterin + 2 H(+) + 2 NADPH."^^xsd:string) AnnotationAssertion( "dihydrobiopterin reduction"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.33e"^^xsd:string) "ptr1 activity"^^xsd:string) AnnotationAssertion(rdfs:label "pteridine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.33"^^xsd:string) "PTR1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.33e"^^xsd:string) "pteridine reductase 1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.33"^^xsd:string) "5,6,7,8-tetrahydrobiopterin:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.254"^^xsd:string) "D-carnitine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.254"^^xsd:string) Annotation( "RHEA:11559"^^xsd:string) "Catalysis of the reaction: (S)-carnitine + NAD(+) = 3-dehydrocarnitine + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.254"^^xsd:string) "(S)-carnitine:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(S)-carnitine 3-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.50"^^xsd:string) "3alpha-hydroxysteroid dehydrogenase (B-specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.50"^^xsd:string) "3-alpha-hydroxysteroid dehydrogenase (B-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.50"^^xsd:string) "3-alpha-HSD activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.50"^^xsd:string) "3alpha-HSD"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.50"^^xsd:string) Annotation( "MetaCyc:1.1.1.50-RXN"^^xsd:string) "Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.50"^^xsd:string) "sterognost 3alpha"^^xsd:string) AnnotationAssertion(rdfs:label "androsterone dehydrogenase (B-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.50"^^xsd:string) "hydroxyprostaglandin dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.50"^^xsd:string) "3alpha-hydroxysteroid oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.50"^^xsd:string) "3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (B-specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.52"^^xsd:string) "3alpha-hydroxycholanate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.52"^^xsd:string) "3alpha-hydroxy-5beta-cholanate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-alpha-hydroxycholanate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.52"^^xsd:string) Annotation( "RHEA:19588"^^xsd:string) "Catalysis of the reaction: lithocholate + NAD(+) = 3-oxo-5beta-cholanate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.52"^^xsd:string) "alpha-hydroxy-cholanate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.53"^^xsd:string) Annotation( "MetaCyc:1.1.1.53-RXN"^^xsd:string) "Catalysis of the reaction: NAD+ + androstan-3-alpha,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.53"^^xsd:string) "dehydrogenase, 20beta-hydroxy steroid"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.53"^^xsd:string) "20beta-HSD"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.53"^^xsd:string) "delta4-3-ketosteroid hydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "androstan-3-alpha,17-beta-diol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.53"^^xsd:string) "3alpha,20beta-hydroxysteroid:NAD+-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.53"^^xsd:string) "NADH-20beta-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.53"^^xsd:string) "3alpha(or 20beta)-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.53"^^xsd:string) "20beta-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.53"^^xsd:string) "cortisone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.53"^^xsd:string) "3-alpha(or 20-beta)-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.53"^^xsd:string) "3alpha(or 20beta)-hydroxysteroid:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.53"^^xsd:string) "(R)-20-hydroxysteroid dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.64"^^xsd:string) "NADP-dependent testosterone-17beta-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.64"^^xsd:string) "testosterone 17beta-dehydrogenase (NADP+)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.64"^^xsd:string) "17beta-hydroxysteroid:NADP+ 17-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.64"^^xsd:string) Annotation( "MetaCyc:1.1.1.64-RXN"^^xsd:string) "Catalysis of the reaction: NADP+ + testosterone = NADPH + H+ + androst-4-ene-3,17-dione."^^xsd:string) AnnotationAssertion(rdfs:label "testosterone 17-beta-dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.64"^^xsd:string) "17-ketoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.87"^^xsd:string) "2-hydroxy-3-carboxyadipate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.87"^^xsd:string) "(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.87"^^xsd:string) "homoisocitric dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.87"^^xsd:string) "(-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD(+) oxidoreductase (decarboxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.87"^^xsd:string) "3-carboxy-2-hydroxyadipate:NAD+ oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.87"^^xsd:string) "(-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD+ oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion( "3-carboxy-2-hydroxyadipate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "homoisocitrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.87"^^xsd:string) "3-carboxy-2-hydroxyadipate:NAD(+) oxidoreductase (decarboxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.155"^^xsd:string) Annotation( "EC:1.1.1.87"^^xsd:string) Annotation( "MetaCyc:1.1.1.87-RXN"^^xsd:string) "Catalysis of the reaction: NAD+ + 3-carboxy-2-hydroxyadipate = NADH + H+ + CO2 + 2-keto-adipate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.92"^^xsd:string) Annotation( "MetaCyc:1.1.1.92-RXN"^^xsd:string) "Catalysis of the reaction: glycerate + CO2 + NAD(P)+ = NAD(P)H + H+ + 2-hydroxy-3-oxosuccinate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.92"^^xsd:string) "D-glycerate:NAD(P)+ oxidoreductase (carboxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "oxaloglycolate reductase (decarboxylating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.97"^^xsd:string) "m-hydroxybenzyl alcohol (NADP) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.97"^^xsd:string) Annotation( "RHEA:22343"^^xsd:string) "Catalysis of the reaction: 3-hydroxybenzyl alcohol + NADP(+) = 3-hydroxybenzaldehyde + H(+) + NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxybenzyl-alcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.97"^^xsd:string) "m-hydroxybenzyl alcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.97"^^xsd:string) "m-hydroxybenzylalcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.97"^^xsd:string) "3-hydroxybenzyl-alcohol:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.98"^^xsd:string) "(R)-2-hydroxystearate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(R)-2-hydroxy-fatty acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.98"^^xsd:string) "2-hydroxy fatty acid oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.98"^^xsd:string) "D-2-hydroxy fatty acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.98"^^xsd:string) Annotation( "RHEA:15952"^^xsd:string) "Catalysis of the reaction: (R)-2-hydroxystearate + NAD(+) = 2-oxostearate + H(+) + NADH."^^xsd:string) AnnotationAssertion( "(R)-2-hydroxy-fatty-acid dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(S)-2-hydroxy-fatty acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.99"^^xsd:string) Annotation( "RHEA:11387"^^xsd:string) "Catalysis of the reaction: (S)-2-hydroxystearate + NAD(+) = 2-oxostearate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.99"^^xsd:string) "dehydrogenase, L-2-hydroxy fatty acid"^^xsd:string) AnnotationAssertion( "(S)-2-hydroxy-fatty-acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.99"^^xsd:string) "2-hydroxy fatty acid oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.99"^^xsd:string) "L-2-hydroxy fatty acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.99"^^xsd:string) "(S)-2-hydroxystearate:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.2.5"^^xsd:string) "(R)-lactate:ferricytochrome-c-553 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-lactate dehydrogenase (cytochrome c-553) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.5"^^xsd:string) Annotation( "MetaCyc:1.1.2.5-RXN"^^xsd:string) "Catalysis of the reaction: 2 ferricytochrome C-553 + D-lactate = 2 ferrocytochrome C-553 + pyruvate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.21.1"^^xsd:string) "(S)-cheilanthifoline oxidase (methylenedioxy-bridge-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.21.1"^^xsd:string) "(S)-cheilanthifoline,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "(S)-stylopine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.21.1"^^xsd:string) Annotation( "RHEA:13776"^^xsd:string) "Catalysis of the reaction: (S)-cheilanthifoline + H(+) + NADPH + O(2) = (S)-stylopine + 2 H(2)O + NADP(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "(S)-scoulerine oxidase (methylenedioxy-bridge-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.21.2"^^xsd:string) Annotation( "RHEA:20488"^^xsd:string) "Catalysis of the reaction: (S)-scoulerine + H(+) + NADPH + O(2) = (S)-cheilanthifoline + 2 H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.21.2"^^xsd:string) "(S)-scoulerine,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "(S)-cheilanthifoline synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.21.3"^^xsd:string) "(S)-N-methylcoclaurine,NADPH:oxygen oxidoreductase (C-O phenol-coupling)"^^xsd:string) AnnotationAssertion(rdfs:label "berbamunine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.21.3"^^xsd:string) Annotation( "MetaCyc:1.1.3.34-RXN"^^xsd:string) "Catalysis of the reaction: O2 + NADPH + H+ + R-N-methylcoclaurine + S-N-methylcoclaurine = 2 H2O + NADP+ + berbamunine."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.21.3"^^xsd:string) "(S)-N-methylcoclaurine oxidase (C-O phenol-coupling) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "salutaridine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.21.4"^^xsd:string) "(R)-reticuline oxidase (C-C phenol-coupling) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.21.4"^^xsd:string) "(R)-reticuline,NADPH:oxygen oxidoreductase (C-C phenol-coupling)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.21.4"^^xsd:string) Annotation( "RHEA:17716"^^xsd:string) "Catalysis of the reaction: (R)-reticuline + H(+) + NADPH + O(2) = 2 H(2)O + NADP(+) + salutaridine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.21.5"^^xsd:string) Annotation( "RHEA:21459"^^xsd:string) "Catalysis of the reaction: (S)-tetrahydrocolumbamine + H(+) + NADPH + O(2) = (S)-canadine + 2 H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(rdfs:label "(S)-canadine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.21.5"^^xsd:string) "(S)-tetrahydrocolumbamine oxidase (methylenedioxy-bridge-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.21.5"^^xsd:string) "(S)-tetrahydroberberine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.21.5"^^xsd:string) "(S)-tetrahydrocolumbamine,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.4.1"^^xsd:string) "phylloquinone epoxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.4.1"^^xsd:string) "vitamin K1 epoxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.4.1"^^xsd:string) "2-methyl-3-phytyl-1,4-naphthoquinone:oxidized-dithiothreitol oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.4.1"^^xsd:string) Annotation( "MetaCyc:1.1.4.1-RXN"^^xsd:string) "Catalysis of the reaction: 2-methyl-3-phytyl-1,4-naphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol."^^xsd:string) AnnotationAssertion(rdfs:label "vitamin-K-epoxide reductase (warfarin-sensitive) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.4.2"^^xsd:string) "3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone:oxidized-dithiothreitol oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.4.2"^^xsd:string) Annotation( "MetaCyc:1.1.4.2-RXN"^^xsd:string) "Catalysis of the reaction: 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.4.2"^^xsd:string) "vitamin K 2,3-epoxide reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "vitamin-K-epoxide reductase (warfarin-insensitive) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.23"^^xsd:string) "polyvinyl-alcohol:(acceptor) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.23"^^xsd:string) "PVA dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "polyvinyl alcohol dehydrogenase (cytochrome) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.6"^^xsd:string) Annotation( ) "polyvinyl alcohol:ferricytochrome-c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.6"^^xsd:string) "Catalysis of the reaction: polyvinyl alcohol + ferricytochrome c = oxidized polyvinyl alcohol + ferrocytochrome c + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.23"^^xsd:string) "polyvinyl-alcohol:acceptor oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.27"^^xsd:string) "2-dehydropantolactone reductase (flavin) activity"^^xsd:string) AnnotationAssertion(rdfs:label "(R)-pantolactone dehydrogenase (flavin) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.27"^^xsd:string) "(R)-pantoyllactone dehydrogenase (flavin) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.27"^^xsd:string) Annotation( "RHEA:21007"^^xsd:string) "Catalysis of the reaction: (R)-pantolactone + A = 2-dehydropantolactone + AH(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.27"^^xsd:string) "(R)-pantolactone:acceptor oxidoreductase (flavin-containing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.27"^^xsd:string) "2-dehydropantoyl-lactone reductase (flavin) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucose-fructose oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.28"^^xsd:string) Annotation( "RHEA:20640"^^xsd:string) "Catalysis of the reaction: D-fructose + D-glucose = D-glucitol + D-glucono-1,5-lactone."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.28"^^xsd:string) "D-glucose:D-fructose oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.10.1.1"^^xsd:string) Annotation( "RHEA:22187"^^xsd:string) "Catalysis of the reaction: (+-)-trans-acenaphthene-1,2-diol + 2 NADP(+) = acenaphthene-1,2-dione + 2 H(+) + 2 NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "trans-acenaphthene-1,2-diol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.1.1"^^xsd:string) "(+-)-trans-acenaphthene-1,2-diol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.1.1"^^xsd:string) "trans-1,2-acenaphthenediol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.10.2.1"^^xsd:string) Annotation( "MetaCyc:1.10.2.1-RXN"^^xsd:string) "Catalysis of the reaction: ferricytochrome B5 + ascorbate = ferrocytochrome B5 + monodehydroascorbate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.1"^^xsd:string) "ascorbate-cytochrome b5 reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-ascorbate-cytochrome-b5 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.2.1"^^xsd:string) "L-ascorbate:ferricytochrome-b5 oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.21.3.4"^^xsd:string) Annotation( "RHEA:24095"^^xsd:string) "Catalysis of the reaction: O(2) + 2 sulochrin = 2 (2S)-bisdechlorogeodin + 2 H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.3.4"^^xsd:string) "sulochrin:oxygen oxidoreductase (cyclizing, (+)-specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.3.4"^^xsd:string) "sulochrin oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulochrin oxidase [(+)-bisdechlorogeodin-forming] activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.21.3.5"^^xsd:string) Annotation( "RHEA:22619"^^xsd:string) "Catalysis of the reaction: O(2) + 2 sulochrin = 2 (2R)-bisdechlorogeodin + 2 H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.3.5"^^xsd:string) "sulochrin:oxygen oxidoreductase (cyclizing, (-)-specific)"^^xsd:string) AnnotationAssertion(rdfs:label "sulochrin oxidase [(-)-bisdechlorogeodin-forming] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.3.5"^^xsd:string) "sulochrin oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.11.1.12"^^xsd:string) "phospholipid hydroperoxide glutathione peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.12"^^xsd:string) "PHGPX"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.12"^^xsd:string) Annotation( "MetaCyc:1.11.1.12-RXN"^^xsd:string) "Catalysis of the reaction: a lipid hydroperoxide + 2 reduced glutathione = 2 H2O + lipid + 2 oxidized glutathione."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.12"^^xsd:string) "peroxidation-inhibiting protein activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.12"^^xsd:string) "hydroperoxide glutathione peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.12"^^xsd:string) "peroxidation-inhibiting protein: peroxidase, glutathione (phospholipid hydroperoxide-reducing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.12"^^xsd:string) "glutathione:lipid-hydroperoxide oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phospholipid-hydroperoxide glutathione peroxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.12.5.1"^^xsd:string) "membrane-bound hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.5.1"^^xsd:string) Annotation( "RHEA:18644"^^xsd:string) "Catalysis of the reaction: H(2) + menaquinone = reduced menaquinone."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.5.1"^^xsd:string) "hydrogen:menaquinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.5.1"^^xsd:string) "quinone-reactive Ni/Fe-hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.5.1"^^xsd:string) "hydrogen-ubiquinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydrogen:quinone oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.12.98.2"^^xsd:string) Annotation( "RHEA:20020"^^xsd:string) "Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2) = 5,10-methylenetetrahydromethanopterin + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.98.2"^^xsd:string) "hydrogen:N5,N10-methenyltetrahydromethanopterin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.98.2"^^xsd:string) "H2-dependent methylene-H4MPT dehydrogenase activity"^^xsd:string) AnnotationAssertion( "N5,N10-methylenetetrahydromethanopterin dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.98.2"^^xsd:string) "H(2)-dependent methylene-H(4)MPT dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.98.2"^^xsd:string) "N(5),N(10)-methenyltetrahydromethanopterin hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.98.2"^^xsd:string) "H(2)-forming N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.98.2"^^xsd:string) "nonmetal hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.98.2"^^xsd:string) "5,10-methenyltetrahydromethanopterin hydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N5,N10-methenyltetrahydromethanopterin hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.98.2"^^xsd:string) "hydrogen:5,10-methenyltetrahydromethanopterin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.98.2"^^xsd:string) "hydrogen:N(5),N(10)-methenyltetrahydromethanopterin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.98.2"^^xsd:string) "H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "7,8-dihydroxykynurenate 8,8a-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.10"^^xsd:string) Annotation( "RHEA:23403"^^xsd:string) "Catalysis of the reaction: 7,8-dihydroxykynurenate + O(2) = 5-(3-carboxylato-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.10"^^xsd:string) "7,8-dihydroxykynurenate oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.10"^^xsd:string) "7,8-dihydroxykynurenate 8,8alpha-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.10"^^xsd:string) "7,8-dihydroxykynurenate:oxygen 8,8a-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.10"^^xsd:string) "7,8-dihydroxykynurenate:oxygen 8,8alpha-oxidoreductase (decyclizing)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.16"^^xsd:string) "3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.16"^^xsd:string) "3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.16"^^xsd:string) "2,3-dihydroxy-beta-phenylpropionic dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.16"^^xsd:string) "2,3-dihydroxy-beta-phenylpropionate oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.16"^^xsd:string) Annotation( "MetaCyc:1.13.11.16-RXN"^^xsd:string) "Catalysis of the reaction: O2 + 3-(2,3-dihydroxyphenyl)propanoate = 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate."^^xsd:string) AnnotationAssertion(rdfs:label "3-carboxyethylcatechol 2,3-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.25"^^xsd:string) "3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione:oxygen 4,5-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.25"^^xsd:string) "3-alkylcatechol 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.25"^^xsd:string) "steroid 4,5-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.25"^^xsd:string) Annotation( "RHEA:21355"^^xsd:string) "Catalysis of the reaction: 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O(2) = 3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.28"^^xsd:string) "2,3-dihydroxybenzoate:oxygen 2,3-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(rdfs:label "2,3-dihydroxybenzoate 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.28"^^xsd:string) Annotation( "RHEA:15372"^^xsd:string) "Catalysis of the reaction: 2,3-dihydroxybenzoate + O(2) = 2-carboxy-cis,cis-muconate + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.28"^^xsd:string) "2,3-dihydroxybenzoate 2,3-oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.41"^^xsd:string) "2,4'-dihydroxyacetophenone oxidoreductase (C-C-bond-cleaving)"^^xsd:string) AnnotationAssertion(rdfs:label "2,4'-dihydroxyacetophenone dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.41"^^xsd:string) Annotation( "RHEA:24419"^^xsd:string) "Catalysis of the reaction: 2,4'-dihydroxyacetophenone + O(2) = 4-hydroxybenzoate + formate + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.41"^^xsd:string) "(4-hydroxybenzoyl)methanol oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-hydroxycatechol 1,2-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.-"^^xsd:string) Annotation( "MetaCyc:R308-RXN"^^xsd:string) "Catalysis of the reaction: O2 + benzene-1,2,4-triol = maleylacetate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.9"^^xsd:string) Annotation( "MetaCyc:1.13.11.9-RXN"^^xsd:string) "Catalysis of the reaction: H2O + O2 + 2,5-dihydroxypyridine = formate + maleamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.9"^^xsd:string) "2,5-dihydroxypyridine:oxygen 5,6-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2,5-dihydroxypyridine 5,6-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.9"^^xsd:string) "2,5-dihydroxypyridine oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.9"^^xsd:string) "pyridine-2,5-diol dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.12.7"^^xsd:string) "luciferase (firefly luciferin)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.7"^^xsd:string) "luciferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.7"^^xsd:string) "Photinus pyralis luciferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.7"^^xsd:string) "Photinus-luciferin 4-monooxygenase (ATP-hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.7"^^xsd:string) "Photinus-luciferin:oxygen 4-oxidoreductase (decarboxylating, ATP-hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.7"^^xsd:string) Annotation( "MetaCyc:1.13.12.7-RXN"^^xsd:string) "Catalysis of the reaction: O2 + ATP + Photinus luciferin = light + diphosphate + AMP + CO2 + oxidized Photinus luciferin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.7"^^xsd:string) "firefly luciferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.7"^^xsd:string) "firefly luciferin luciferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.7"^^xsd:string) "Photinus luciferin 4-monooxygenase (adenosine triphosphate-hydrolyzing)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.47"^^xsd:string) "3-hydroxy-4-oxo-1,4-dihydroquinoline 2,4-dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.47"^^xsd:string) "3-hydroxy-1H-quinolin-4-one 2,4-dioxygenase (CO-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.47"^^xsd:string) Annotation( "MetaCyc:1.13.11.47-RXN"^^xsd:string) "Catalysis of the reaction: O2 + 3-hydroxy-1H-quinolin-4-one = carbon monoxide + N-formylanthranilate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.47"^^xsd:string) "3-hydroxy-4(1H)-one, 2,4-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.47"^^xsd:string) "(1H)-3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.47"^^xsd:string) "quinoline-3,4-diol 2,4-dioxygenase activity"^^xsd:string) AnnotationAssertion( "1H-3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.10"^^xsd:string) Annotation( "RHEA:23319"^^xsd:string) "Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O(2) = 2-deoxy-D-ribono-1,4-lactone + CO(2) + succinate + uracil."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.10"^^xsd:string) "pyrimidine-deoxynucleoside,2-oxoglutarate 1'-dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "deoxyuridine 1'-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.10"^^xsd:string) "pyrimidine-deoxynucleoside 1'-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.10"^^xsd:string) "2'-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (1'-hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.3"^^xsd:string) "pyrimidine deoxyribonucleoside 2'-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.3"^^xsd:string) "pyrimidine-deoxynucleoside 2'-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.3"^^xsd:string) "thymidine dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.3"^^xsd:string) "thymidine 2'-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.3"^^xsd:string) "deoxyuridine 2'-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "deoxyuridine 2'-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.3"^^xsd:string) Annotation( "RHEA:21079"^^xsd:string) "Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O(2) = CO(2) + succinate + uridine."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.3"^^xsd:string) "thymidine 2-oxoglutarate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.3"^^xsd:string) "pyrimidine-deoxynucleoside,2-oxoglutarate 2'-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.3"^^xsd:string) "thymidine 2'-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.3"^^xsd:string) "2'-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (2'-hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.12.4"^^xsd:string) "methylhydroxypyridine carboxylate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.4"^^xsd:string) "3-hydroxy-2-methylpyridine-5-carboxylate,NAD(P)H:oxygen oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.4"^^xsd:string) "methylhydroxypyridinecarboxylate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.4"^^xsd:string) Annotation( "MetaCyc:1.14.12.4-RXN"^^xsd:string) "Catalysis of the reaction: O2 + NAD(P)H + H+ + 3-hydroxy-2-methylpyridine-5-carboxylate = NAD(P)+ + 2-(acetamidomethylene)succinate."^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.4"^^xsd:string) "3-hydroxy-3-methylpyridinecarboxylate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.4"^^xsd:string) "2-methyl-3-hydroxypyridine 5-carboxylic acid dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.28"^^xsd:string) "3,9-dihydroxypterocarpan 6alpha-monooxygenase (erroneous)"^^xsd:string) AnnotationAssertion( "3,9-dihydroxypterocarpan 6a-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.28"^^xsd:string) Annotation( "RHEA:15324"^^xsd:string) "Catalysis of the reaction: (6aR,11aR)-3,9-dihydroxypterocarpan + H(+) + NADPH + O(2) = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + H(2)O + NADP(+). (6aS,11aS)-3,6a,9-trihydroxypterocarpan is also known as (-)-glycinol."^^xsd:string) AnnotationAssertion(rdfs:label "3,9-dihydroxypterocarpan 6a-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.28"^^xsd:string) "(6aR,11aR)-3,9-dihydroxypterocarpan,NADPH:oxygen oxidoreductase (6a-hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.36"^^xsd:string) "trans-5-O-(4-coumaroyl)-D-quinate,NADPH:oxygen oxidoreductase (3'-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.36"^^xsd:string) Annotation( "MetaCyc:1.14.13.36-RXN"^^xsd:string) "Catalysis of the reaction: O2 + NADPH + H+ + trans-5-O-(4-coumaroyl)-D-quinate = H2O + NADP+ + trans-5-O-caffeoyl-D-quinate."^^xsd:string) AnnotationAssertion( "5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.36"^^xsd:string) "coumaroylquinate(coumaroylshikimate) 3'-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methyltetrahydroprotoberberine 14-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.37"^^xsd:string) "(S)-cis-N-methyltetrahydroberberine 14-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.37"^^xsd:string) "(S)-cis-N-methyltetrahydroprotoberberine-14-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.37"^^xsd:string) "(S)-N-methylcanadine,NADPH:oxygen oxidoreductase (14-hydroxylating)"^^xsd:string) AnnotationAssertion( "methyltetrahydroprotoberberine 14-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.37"^^xsd:string) Annotation( "MetaCyc:1.14.13.37-RXN"^^xsd:string) "Catalysis of the reaction: O2 + NADPH + H+ + (S)-N-methylcanadine = H2O + NADP+ + allocryptopine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.42"^^xsd:string) "4-hydroxyphenylacetonitrile,NADPH:oxygen oxidoreductase (2-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.42"^^xsd:string) "4-hydroxyphenylacetonitrile hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydroxyphenylacetonitrile 2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:23743"^^xsd:string) "Catalysis of the reaction: 4-hydroxyphenylacetonitrile + H(+) + NADPH + O(2) = 4-hydroxymandelonitrile + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion( "4-hydroxyphenylacetonitrile monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.54"^^xsd:string) "17alpha-hydroxyprogesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, side-chain cleaving)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.54"^^xsd:string) "progesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, ester-producing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.54"^^xsd:string) "ketosteroid,NADPH:oxygen oxidoreductase (20-hydroxylating, ester-producing/20-hydroxylating, side-chain cleaving/17-hydroxylating, lactonizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.54"^^xsd:string) "androstenedione, NADPH2:oxygen oxidoreductase (17-hydroxylating, lactonizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.54"^^xsd:string) "steroid-ketone monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.54"^^xsd:string) Annotation( "MetaCyc:1.14.13.54-RXN"^^xsd:string) "Catalysis of the reaction: O2 + NADPH + progesterone = H2O + NADP+ + testosterone acetate."^^xsd:string) AnnotationAssertion(rdfs:label "ketosteroid monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.55"^^xsd:string) Annotation( "RHEA:22647"^^xsd:string) "Catalysis of the reaction: H(+) + NADPH + O(2) + protopine = 6-hydroxyprotopine + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(rdfs:label "protopine 6-monooxygenase activity"^^xsd:string) AnnotationAssertion( "protopine 6-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.55"^^xsd:string) "protopine,NADPH:oxygen oxidoreductase (6-hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.56"^^xsd:string) Annotation( "RHEA:10531"^^xsd:string) "Catalysis of the reaction: dihydrosanguinarine + H(+) + NADPH + O(2) = 10-hydroxydihydrosanguinarine + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.56"^^xsd:string) "dihydrosanguinarine,NADPH:oxygen oxidoreductase (10-hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "dihydrosanguinarine 10-monooxygenase activity"^^xsd:string) AnnotationAssertion( "dihydrosanguinarine 10-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dihydrochelirubine 12-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.57"^^xsd:string) "dihydrochelirubine,NADPH:oxygen oxidoreductase (12-hydroxylating)"^^xsd:string) AnnotationAssertion( "dihydrochelirubine 12-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.57"^^xsd:string) Annotation( "RHEA:10159"^^xsd:string) "Catalysis of the reaction: dihydrochelirubine + H(+) + NADPH + O(2) = 12-hydroxydihydrochelirubine + H(2)O + NADP(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.58"^^xsd:string) Annotation( "RHEA:23219"^^xsd:string) "Catalysis of the reaction: benzoyl-CoA + H(+) + NADPH + O(2) = 3-hydroxybenzoyl-CoA + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(rdfs:label "benzoyl-CoA 3-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.58"^^xsd:string) "benzoyl-CoA,NADPH:oxygen oxidoreductase (3-hydroxylating)"^^xsd:string) AnnotationAssertion( "benzoyl-CoA 3-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.59"^^xsd:string) Annotation( "RHEA:23231"^^xsd:string) "Catalysis of the reaction: L-lysine + NADPH + O(2) = N(6)-hydroxy-L-lysine + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.59"^^xsd:string) "lysine N(6)-hydroxylase activity"^^xsd:string) AnnotationAssertion( "L-lysine 6-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.59"^^xsd:string) "L-lysine,NADPH:oxygen oxidoreductase (6-hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "L-lysine 6-monooxygenase (NADPH) activity"^^xsd:string) AnnotationAssertion( "lysine N6-hydroxylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "27-hydroxycholesterol 7-alpha-monooxygenase activity"^^xsd:string) AnnotationAssertion( "27-hydroxycholesterol 7a-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.60"^^xsd:string) "27-hydroxycholesterol 7-alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.60"^^xsd:string) Annotation( "MetaCyc:1.14.13.60-RXN"^^xsd:string) "Catalysis of the reaction: O2 + NADPH + 27-hydroxycholesterol = H2O + NADP+ + 7-alpha,27-dihydroxycholesterol."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.60"^^xsd:string) "27-hydroxycholesterol 7alpha-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.60"^^xsd:string) "27-hydroxycholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.60"^^xsd:string) "27-hydroxycholesterol 7alpha-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-hydroxyquinoline 3-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.62"^^xsd:string) "1-H-4-oxoquinoline 3-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.62"^^xsd:string) "quinolin-4(1H)-one 3-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.62"^^xsd:string) "quinolin-4(1H)-one,NADH:oxygen oxidoreductase (3-oxygenating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.62"^^xsd:string) Annotation( "RHEA:19328"^^xsd:string) "Catalysis of the reaction: H(+) + NADH + O(2) + quinolin-4-ol = H(2)O + NAD(+) + quinoline-3,4-diol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.63"^^xsd:string) "3-hydroxyphenylacetate,NAD(P)H:oxygen oxidoreductase (6-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.63"^^xsd:string) Annotation( "MetaCyc:1.14.13.63-RXN"^^xsd:string) "Catalysis of the reaction: O2 + NAD(P)H + 3-hydroxyphenylacetate = H2O + NAD(P)+ + homogentisate."^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxyphenylacetate 6-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.63"^^xsd:string) "3-hydroxyphenylacetate 6-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.66"^^xsd:string) "2-hydroxycyclohexan-1-one,NADPH:oxygen 2-oxidoreductase (1,2-lactonizing)"^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxycyclohexanone 2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.66"^^xsd:string) Annotation( "RHEA:25172"^^xsd:string) "Catalysis of the reaction: 2-hydroxycyclohexan-1-one + NADPH + O(2) = 6-oxohexanoate + H(2)O + NADP(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.12"^^xsd:string) "androst-4-ene-3,17-dione 17-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "androst-4-ene-3,17-dione monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.12"^^xsd:string) "androst-4-ene-3,17-dione hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.12"^^xsd:string) Annotation( "RHEA:22699"^^xsd:string) "Catalysis of the reaction: AH(2) + androst-4-ene-3,17-dione + O(2) = A + H(2)O + testololactone."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.12"^^xsd:string) "androst-4-ene-3,17-dione-hydrogen-donor:oxygen oxidoreductase (13-hydroxylating, lactonizing)"^^xsd:string) AnnotationAssertion( "androstene-3,17-dione hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.12"^^xsd:string) "androstenedione monooxygenase activity"^^xsd:string) AnnotationAssertion( "4-androstene-3,17-dione monooxygenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.20"^^xsd:string) "phylloquinone,hydrogen-donor:oxygen oxidoreductase (2,3-epoxidizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.20"^^xsd:string) "vitamin K 2,3-epoxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phylloquinone monooxygenase (2,3-epoxidizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.20"^^xsd:string) "phylloquinone epoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.20"^^xsd:string) Annotation( "RHEA:16748"^^xsd:string) "Catalysis of the reaction: AH(2) + O(2) + phylloquinone = 2,3-epoxyphylloquinone + A + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.20"^^xsd:string) "vitamin K epoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.20"^^xsd:string) "vitamin K1 epoxidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.21"^^xsd:string) Annotation( "MetaCyc:1.14.99.21-RXN"^^xsd:string) "Catalysis of the reaction: 2 O2 + donor-H2 + Latia luciferin = light + H2O + acceptor + formate + CO2 + oxidized Latia luciferin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.21"^^xsd:string) "luciferase (Latia luciferin)"^^xsd:string) AnnotationAssertion(rdfs:label "Latia-luciferin monooxygenase (demethylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.21"^^xsd:string) "Latia luciferin monooxygenase (demethylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.21"^^xsd:string) "Latia-luciferin,hydrogen-donor:oxygen oxidoreductase (demethylating)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.17.1.1"^^xsd:string) "CDP-4-dehydro-3,6-dideoxy-D-glucose:NAD(P)+ 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.1"^^xsd:string) "cytidine diphosphate 4-keto-6-deoxy-D-glucose-3-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.1"^^xsd:string) "CDP-4-keto-6-deoxyglucose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.1"^^xsd:string) "CDP-4-keto-deoxy-glucose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.1"^^xsd:string) Annotation( "MetaCyc:1.17.1.1-RXN"^^xsd:string) "Catalysis of the reaction: H2O + NAD(P)+ + CDP-4-dehydro-3,6-dideoxy-D-glucose = NAD(P)H + CDP-4-dehydro-6-deoxy-D-glucose."^^xsd:string) AnnotationAssertion(rdfs:label "CDP-4-dehydro-6-deoxyglucose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.1"^^xsd:string) "cytidine diphospho-4-keto-6-deoxy-D-glucose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.1"^^xsd:string) "NAD(P)H:CDP-4-keto-6-deoxy-D-glucose oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.1"^^xsd:string) "CDP-4-keto-6-deoxy-D-glucose-3-dehydrogenase system activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.13"^^xsd:string) "NADP-dependent glyceraldehyde-3-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.13"^^xsd:string) "NADP-dependent glyceraldehyde phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.13"^^xsd:string) Annotation( "MetaCyc:1.2.1.13-RXN"^^xsd:string) "Catalysis of the reaction: phosphate + NADP+ + glyceraldehyde-3-phosphate = NADPH + 3-phospho-D-glyceroyl-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.13"^^xsd:string) "NADP-triose phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.13"^^xsd:string) "triosephosphate dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.13"^^xsd:string) "D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.13"^^xsd:string) "triosephosphate dehydrogenase (NADP)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.13"^^xsd:string) "triosephosphate dehydrogenase (NADP(+)) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.13"^^xsd:string) "glyceraldehyde phosphate dehydrogenase (nicotinamide adenine dinucleotide phosphate) (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.13"^^xsd:string) "dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate) (phosphorylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.25"^^xsd:string) Annotation( "MetaCyc:1.2.1.25-RXN"^^xsd:string) "Catalysis of the reaction: NAD+ + CoA + 2-keto-isovalerate = NADH + CO2 + isobutyryl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.25"^^xsd:string) "3-methyl-2-oxobutanoate:NAD+ 2-oxidoreductase (CoA-methyl-propanoylating)"^^xsd:string) AnnotationAssertion(rdfs:label "2-oxoisovalerate dehydrogenase (acylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.25"^^xsd:string) "2-oxoisovalerate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.32"^^xsd:string) "alpha-aminomuconic epsilon-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.32"^^xsd:string) "2-hydroxymuconic acid semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.32"^^xsd:string) Annotation( "MetaCyc:1.2.1.32-RXN"^^xsd:string) "Catalysis of the reaction: H2O + NAD+ + 2-aminomuconate semialdehyde = NADH + 2-amino-muconate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.32"^^xsd:string) "2-aminomuconate-6-semialdehyde:NAD+ 6-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.32"^^xsd:string) "2-hydroxymuconate semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.32"^^xsd:string) "2-aminomuconate semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.32"^^xsd:string) "alpha-hydroxymuconic epsilon-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.32"^^xsd:string) "2-hydroxymuconic semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aminomuconate-semialdehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.40"^^xsd:string) "THAL-NAD oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.40"^^xsd:string) "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.40"^^xsd:string) Annotation( "MetaCyc:1.2.1.40-RXN"^^xsd:string) "Catalysis of the reaction: H2O + NAD+ + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al = NADH + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.40"^^xsd:string) "cholestanetriol-26-al 26-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.40"^^xsd:string) "3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.40"^^xsd:string) "3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.40"^^xsd:string) "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al:NAD+ 26-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.40"^^xsd:string) "trihydroxydeoxycoprostanal dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.40"^^xsd:string) "3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.42"^^xsd:string) Annotation( "RHEA:19708"^^xsd:string) "Catalysis of the reaction: CoA + NAD(+) + palmitaldehyde = H(+) + NADH + palmitoyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.42"^^xsd:string) "fatty acyl-CoA reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hexadecanal dehydrogenase (acylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.42"^^xsd:string) "hexadecanal:NAD+ oxidoreductase (CoA-acylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.47"^^xsd:string) Annotation( "MetaCyc:1.2.1.47-RXN"^^xsd:string) "Catalysis of the reaction: NAD+ + 4-trimethylammoniobutanal = NADH + 4-trimethylammoniobutanoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.47"^^xsd:string) "4-N-trimethylaminobutyraldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-trimethylammoniobutyraldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.47"^^xsd:string) "4-trimethylammoniobutanal:NAD+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.47"^^xsd:string) "4-trimethylaminobutyraldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-hydroxyphenylacetaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.53"^^xsd:string) "4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.53"^^xsd:string) Annotation( "MetaCyc:1.2.1.53-RXN"^^xsd:string) "Catalysis of the reaction: NAD+ + (4-hydroxyphenyl)acetaldehyde + H2O = NADH + 4-hydroxyphenylacetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.53"^^xsd:string) "4-HPAL dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.54"^^xsd:string) "GBAL dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.54"^^xsd:string) "alpha-guanidinobutyraldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.54"^^xsd:string) "4-guanidinobutanal:NAD+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.54"^^xsd:string) Annotation( "RHEA:14384"^^xsd:string) "Catalysis of the reaction: 4-guanidinobutanal + H(2)O + NAD(+) = 4-guanidinobutanoate + 2 H(+) + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "gamma-guanidinobutyraldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.54"^^xsd:string) "4-guanidinobutyraldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.279"^^xsd:string) "ethyl-(R)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion( "(R)-3-hydroxyacid ester dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.279"^^xsd:string) "3-oxo ester (R)-reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(R)-3-hydroxyacid-ester dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.279"^^xsd:string) Annotation( "RHEA:24355"^^xsd:string) "Catalysis of the reaction: ethyl (R)-3-hydroxyhexanoate + NADP(+) = ethyl 3-oxohexanoate + H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(S)-3-hydroxyacid-ester dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.280"^^xsd:string) "3-oxo ester (S)-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.280"^^xsd:string) Annotation( "RHEA:18272"^^xsd:string) "Catalysis of the reaction: ethyl (S)-3-hydroxyhexanoate + NADP(+) = ethyl 3-oxohexanoate + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.280"^^xsd:string) "ethyl-(S)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion( "(S)-3-hydroxyacid ester dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phenylglyoxylate dehydrogenase (acylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.58"^^xsd:string) Annotation( "RHEA:10375"^^xsd:string) "Catalysis of the reaction: CoA + NAD(+) + phenylglyoxylate = benzoyl-CoA + CO(2) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.58"^^xsd:string) "phenylglyoxylate:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.2.3"^^xsd:string) "formate dehydrogenase (cytochrome c-553)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.2.3"^^xsd:string) "formate:ferricytochrome-c-553 oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "formate dehydrogenase (cytochrome-c-553) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.2.3"^^xsd:string) Annotation( "MetaCyc:1.2.2.3-RXN"^^xsd:string) "Catalysis of the reaction: ferricytochrome C-553 + formate = ferrocytochrome C-553 + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.3.3"^^xsd:string) Annotation( "RHEA:20851"^^xsd:string) "Catalysis of the reaction: H(+) + O(2) + phosphate + pyruvate = acetyl phosphate + CO(2) + H(2)O(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.3"^^xsd:string) "phosphate-dependent pyruvate oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyruvate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.3"^^xsd:string) "pyruvic oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.3"^^xsd:string) "pyruvate:oxygen 2-oxidoreductase (phosphorylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.99.3"^^xsd:string) "aldehyde:(pyrroloquinoline-quinone) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.99.3"^^xsd:string) Annotation( "MetaCyc:1.2.99.3-RXN"^^xsd:string) "Catalysis of the reaction: an aldehyde + acceptor + H2O = a carboxylate + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.99.3"^^xsd:string) "aldehyde dehydrogenase (acceptor) activity"^^xsd:string) AnnotationAssertion(rdfs:label "aldehyde dehydrogenase (pyrroloquinoline-quinone) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.18"^^xsd:string) "7,8-dihydro-7,8-dihydroxykynurenate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "kynurenate-7,8-dihydrodiol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.18"^^xsd:string) "7,8-dihydroxykynurenic acid 7,8-diol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.18"^^xsd:string) "7,8-dihydro-7,8-dihydroxykynurenate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.18"^^xsd:string) Annotation( "RHEA:22251"^^xsd:string) "Catalysis of the reaction: 7,8-dihydro-7,8-dihydroxykynurenate + NAD(+) = 7,8-dihydroxykynurenate + H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.20"^^xsd:string) "trans-1,2-dihydrobenzene-1,2-diol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.20"^^xsd:string) "dihydrodiol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.20"^^xsd:string) Annotation( "MetaCyc:1.3.1.20-RXN"^^xsd:string) "Catalysis of the reaction: NADP+ + trans-1,2-dihydrobenzene-1,2-diol = NADPH + catechol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.25"^^xsd:string) "DHB dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.25"^^xsd:string) "cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.25"^^xsd:string) "2-hydro-1,2-dihydroxybenzoate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.25"^^xsd:string) "3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.25"^^xsd:string) "dihydrodihydroxybenzoate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.25"^^xsd:string) "DHBDH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.25"^^xsd:string) Annotation( "MetaCyc:1.3.1.25-RXN"^^xsd:string) "Catalysis of the reaction: NAD+ + 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate = NADH + CO2 + catechol."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.25"^^xsd:string) "3,5-cyclohexadiene-1,2-diol-1-carboxylic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.25"^^xsd:string) "(1R,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.25"^^xsd:string) "cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD(+) oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.39"^^xsd:string) "enoyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide phosphate) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.39"^^xsd:string) "enoyl-acyl-carrier-protein reductase (NADPH, A-specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.39"^^xsd:string) "acyl-acyl-carrier-protein:NADP+ oxidoreductase (A-specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.39"^^xsd:string) "enoyl-ACp reductase activity"^^xsd:string) AnnotationAssertion( "enoyl-[acyl-carrier protein] reductase (NADPH, A-specific) activity"^^xsd:string) AnnotationAssertion( "enoyl-ACP reductase (NADPH, A-specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.39"^^xsd:string) Annotation( "MetaCyc:1.3.1.39-RXN"^^xsd:string) "Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-D2-enoyl-[acyl-carrier protein] + NADPH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.40"^^xsd:string) "2-hydroxy-6-oxo-phenylhexa-2,4-dienoate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.40"^^xsd:string) "2,6-dioxo-6-phenylhexanoate:NADP+ delta2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.40"^^xsd:string) Annotation( "RHEA:24271"^^xsd:string) "Catalysis of the reaction: 2,6-dioxo-6-phenylhexanoate + NADP(+) = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.52"^^xsd:string) Annotation( "RHEA:24535"^^xsd:string) "Catalysis of the reaction: 2-methylbutanoyl-CoA + NAD(+) = 2-methylbut-2-enoyl-CoA + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.52"^^xsd:string) "2-methyl-branched-chain-acyl-CoA:NAD+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-methyl-branched-chain-enoyl-CoA reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "terephthalate 1,2-cis-dihydrodiol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.53"^^xsd:string) "(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.53"^^xsd:string) "dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.53"^^xsd:string) Annotation( "RHEA:10747"^^xsd:string) "Catalysis of the reaction: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+) = 3,4-dihydroxybenzoate + CO(2) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.53"^^xsd:string) "(1R,2S)-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.53"^^xsd:string) "cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,4-dicarboxylate:NAD+ oxidoreductase (decarboxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.99.16"^^xsd:string) "isoquinoline:acceptor 1-oxidoreductase (hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "isoquinoline 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.16"^^xsd:string) Annotation( "RHEA:11591"^^xsd:string) "Catalysis of the reaction: A + H(2)O + isoquinoline = AH(2) + isoquinolin-1(2H)-one."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.99.18"^^xsd:string) Annotation( "RHEA:16700"^^xsd:string) "Catalysis of the reaction: A + H(2)O + quinaldate = AH(2) + kynurenate."^^xsd:string) AnnotationAssertion(rdfs:label "quinaldate 4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.18"^^xsd:string) "quinaldic acid 4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.18"^^xsd:string) "quinoline-2-carboxylate:acceptor 4-oxidoreductase (hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "quinoline-4-carboxylate 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.19"^^xsd:string) Annotation( "RHEA:14952"^^xsd:string) "Catalysis of the reaction: A + H(2)O + quinoline-4-carboxylate = 2-oxo-1,2-dihydroquinoline-4-carboxylate + AH(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.19"^^xsd:string) "quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.19"^^xsd:string) "quinoline-4-carboxylic acid 2-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-erythro-3,5-diaminohexanoate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.11"^^xsd:string) Annotation( "RHEA:19636"^^xsd:string) "Catalysis of the reaction: (3S,5S)-3,5-diaminohexanoate + H(2)O + NAD(+) = (S)-5-amino-3-oxo-hexanoate + H(+) + NADH + NH(4)(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.11"^^xsd:string) "L-erythro-3,5-diaminohexanoate:NAD+ oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.11"^^xsd:string) "L-3,5-diaminohexanoate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "delta 1-piperideine-2-carboxylate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.21"^^xsd:string) "L-pipecolate:NADP+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.21"^^xsd:string) "Catalysis of the reaction: NADP+ + L-pipecolate = NADPH + delta1-piperideine-2-carboxylate."^^xsd:string) AnnotationAssertion( "D1-piperideine-2-carboxylate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.21"^^xsd:string) "P2C reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.21"^^xsd:string) "1,2-didehydropipecolate reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "delta1-piperideine-2-carboxylate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.21"^^xsd:string) "1,2-didehydropipecolic reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.24"^^xsd:string) "N5-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.24"^^xsd:string) Annotation( "RHEA:18664"^^xsd:string) "Catalysis of the reaction: N(5)-[1(S)-1-carboxyethyl]-L-ornithine + H(2)O + NADP(+) = L-ornithine + H(+) + NADPH + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.24"^^xsd:string) "5-N-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "N5-(carboxyethyl)ornithine synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.25"^^xsd:string) Annotation( "MetaCyc:1.5.1.25-RXN"^^xsd:string) "Catalysis of the reaction: NAD(P)+ + thiomorpholine-3-carboxylate = NAD(P)H + 3,4-dehydro-1,4-thiomorpholine-3-carboxylate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.25"^^xsd:string) "ketimine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.25"^^xsd:string) "thiomorpholine-3-carboxylate:NAD(P)+ 5,6-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.25"^^xsd:string) "ketimine-reducing enzyme"^^xsd:string) AnnotationAssertion(rdfs:label "thiomorpholine-carboxylate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.27"^^xsd:string) Annotation( "RHEA:17572"^^xsd:string) "Catalysis of the reaction: (R)-reticuline + NADP(+) = 1,2-dehydroreticuline + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.27"^^xsd:string) "1,2-dehydroreticulinium ion reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1,2-dehydroreticulinium reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.27"^^xsd:string) "(R)-reticuline:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "opine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.28"^^xsd:string) "(2S)-2-{[1-(R)-carboxyethyl]amino}pentanoate:NAD+ oxidoreductase (L-aminopentanoate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.28"^^xsd:string) Annotation( "RHEA:21595"^^xsd:string) "Catalysis of the reaction: (2S)-2-[(R)-1-carboxyethylamino]pentanoate + H(2)O + NAD(+) = L-2-aminopentanoate + H(+) + NADH + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.28"^^xsd:string) "(2S)-2-{[1-(R)-carboxyethyl]amino}pentanoate dehydrogenase (NAD, L-aminopentanoate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.8"^^xsd:string) "L-lysine-alpha-ketoglutarate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.8"^^xsd:string) "lysine:alpha-ketoglutarate:TPNH oxidoreductase (epsilon-N-[gultaryl-2]-L-lysine forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.8"^^xsd:string) Annotation( "RHEA:19376"^^xsd:string) "Catalysis of the reaction: L-saccharopine + H(2)O + NADP(+) = 2-oxoglutarate + L-lysine + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.8"^^xsd:string) "N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.8"^^xsd:string) "6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "saccharopine dehydrogenase (NADP+, L-lysine-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.8"^^xsd:string) "saccharopine (nicotinamide adenine dinucleotide phosphate, lysine-forming) dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.9"^^xsd:string) "saccharopin dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.9"^^xsd:string) "dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, glutamate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.9"^^xsd:string) Annotation( "RHEA:24523"^^xsd:string) "Catalysis of the reaction: L-saccharopine + H(2)O + NAD(+) = L-glutamate + allysine + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.9"^^xsd:string) "N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.9"^^xsd:string) "aminoadipic semialdehyde synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.9"^^xsd:string) "NAD+ oxidoreductase (L-2-aminoadipic-delta-semialdehyde and glutamate forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.9"^^xsd:string) "6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.3.12"^^xsd:string) "dihydrobenzophenanthridine:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.12"^^xsd:string) Annotation( "MetaCyc:1.5.3.12-RXN"^^xsd:string) "Catalysis of the reaction: O2 + dihydrosanguinarine = H2O2 + sanguinarine."^^xsd:string) AnnotationAssertion(rdfs:label "dihydrobenzophenanthridine oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.8.1"^^xsd:string) "dimethylamine:electron-transferring flavoprotein oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.8.1"^^xsd:string) "DMADh activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.8.1"^^xsd:string) Annotation( "MetaCyc:1.5.8.1-RXN"^^xsd:string) "Catalysis of the reaction: electron-transferring flavoprotein + H2O + dimethylamine = reduced electron-transferring flavoprotein + formaldehyde + methylamine."^^xsd:string) AnnotationAssertion(rdfs:label "dimethylamine dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.1.8"^^xsd:string) "disulfide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.8"^^xsd:string) "protein disulphide reductase activity"^^xsd:string) AnnotationAssertion( "protein-disulfide reductase (NAD(P)H) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.8"^^xsd:string) "NAD(P)H2:protein-disulfide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.8"^^xsd:string) Annotation( "MetaCyc:1.6.4.4-RXN"^^xsd:string) "Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(rdfs:label "protein-disulfide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.8"^^xsd:string) "NAD(P)H:protein-disulfide oxidoreductase activity"^^xsd:string) AnnotationAssertion( "protein-disulphide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.8"^^xsd:string) "protein disulfide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.8"^^xsd:string) "insulin-glutathione transhydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.8"^^xsd:string) "protein-dithiol:NAD(P)+ oxidoreductase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.1.13"^^xsd:string) "NADPH:bis-gamma-glutamylcysteine oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.13"^^xsd:string) "NADPH2:bis-gamma-glutamylcysteine oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.13"^^xsd:string) "Bis-gamma-glutamylcystine reductase (NADPH)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.13"^^xsd:string) "gamma-glutamylcysteine:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.13"^^xsd:string) "bis-gamma-glutamylcystine reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(rdfs:label "bis-gamma-glutamylcystine reductase activity"^^xsd:string) AnnotationAssertion( "bis-g-glutamylcystine reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.13"^^xsd:string) Annotation( "RHEA:11983"^^xsd:string) "Catalysis of the reaction: 2 L-gamma-glutamyl-L-cysteine + NADP(+) = bis-gamma-glutamylcystine + H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.1.11"^^xsd:string) Annotation( "RHEA:19792"^^xsd:string) "Catalysis of the reaction: 4-(dimethylamino)azobenzene + H(2)O + NADP(+) = 4-(dimethylamino)phenylazoxybenzene + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.11"^^xsd:string) "4-(dimethylamino)phenylazobenzene:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.11"^^xsd:string) "NADPH:4-(dimethylamino)phenylazoxybenzene oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.11"^^xsd:string) "dimethylaminoazobenzene N-oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.11"^^xsd:string) "N,N-dimethyl-p-aminoazobenzene oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.11"^^xsd:string) "NADPH2:4-(dimethylamino)phenylazoxybenzene oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.11"^^xsd:string) "NADPH-dependent DMAB N-oxide reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-(dimethylamino)phenylazoxybenzene reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-hydroxy-2-acetamidofluorene reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.12"^^xsd:string) "NAD(P)H2:N-hydroxy-2-acetamidofluorene N-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.12"^^xsd:string) "NAD(P)H:N-hydroxy-2-acetamidofluorene N-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.12"^^xsd:string) "2-acetamidofluorene:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.12"^^xsd:string) Annotation( "MetaCyc:1.7.1.12-RXN"^^xsd:string) "Catalysis of the reaction: 2-acetamidofluorene + NAD(P)+ + H2O = N-hydroxy-2-acetamidofluorene + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.12"^^xsd:string) "N-hydroxy-2-acetylaminofluorene reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.16.1.3"^^xsd:string) "cob(II)alamin:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aquacobalamin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.3"^^xsd:string) "NADH-linked aquacobalamin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.3"^^xsd:string) "NADH:cob(III)alamin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.3"^^xsd:string) "NADH2:cob(III)alamin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.3"^^xsd:string) "vitamin B12a reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.3"^^xsd:string) "aquocobalamin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.3"^^xsd:string) "B(12a) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.3"^^xsd:string) "vitamin B(12a) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.3"^^xsd:string) Annotation( "MetaCyc:1.6.99.12-RXN"^^xsd:string) "Catalysis of the reaction: 2 cob(II)alamin + NAD+ = 2 aquacob(III)alamin + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.3"^^xsd:string) "B12a reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.4.1"^^xsd:string) Annotation( "MetaCyc:1.8.4.1-RXN"^^xsd:string) "Catalysis of the reaction: homocystine + 2 reduced glutathione = oxidized glutathione + 2 homocysteine."^^xsd:string) AnnotationAssertion(rdfs:label "glutathione-homocystine transhydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.1"^^xsd:string) "glutathione:homocystine oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.4.3"^^xsd:string) "CoA:glutathione-disulfide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.3"^^xsd:string) Annotation( "MetaCyc:1.8.4.3-RXN"^^xsd:string) "Catalysis of the reaction: oxidized glutathione + CoA = reduced glutathione + CoA-glutathione."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.3"^^xsd:string) "glutathione:coenzyme A-glutathione transhydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutathione-CoA-glutathione transhydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.3"^^xsd:string) "glutathione-coenzyme A glutathione disulfide transhydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.3"^^xsd:string) "glutathione coenzyme A-glutathione transhydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.3"^^xsd:string) "coenzyme A:glutathione-disulfide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.3"^^xsd:string) "coenzyme A:oxidized-glutathione oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutathione-cystine transhydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.4"^^xsd:string) "GSH-cystine transhydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.4"^^xsd:string) Annotation( "MetaCyc:1.8.4.4-RXN"^^xsd:string) "Catalysis of the reaction: cystine + 2 reduced glutathione = oxidized glutathione + 2 L-cysteine."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.4"^^xsd:string) "NADPH-dependent GSH-cystine transhydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.4"^^xsd:string) "glutathione:cystine oxidoreductase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.4.7"^^xsd:string) "xanthine-dehydrogenase:glutathione-disulfide S-oxidoreductase activity"^^xsd:string) AnnotationAssertion( "enzyme-thiol transhydrogenase (glutathione-disulphide) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.7"^^xsd:string) "thiol:disulfide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.7"^^xsd:string) "thiol:disulphide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.7"^^xsd:string) "xanthine-dehydrogenase:oxidized-glutathione S-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "enzyme-thiol transhydrogenase (glutathione-disulfide) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.7"^^xsd:string) "[xanthine-dehydrogenase]:oxidized-glutathione S-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.7"^^xsd:string) Annotation( "MetaCyc:1.8.4.7-RXN"^^xsd:string) "Catalysis of the reaction: oxidized glutathione + [xanthine dehydrogenase] = reduced glutathione + xanthine-oxidase."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.4.7"^^xsd:string) "glutathione-dependent thiol:disulfide oxidoreductase activity"^^xsd:string) AnnotationAssertion( "enzyme-thiol transhydrogenase (oxidized-glutathione) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chlorate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.1"^^xsd:string) "chlorite:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.1"^^xsd:string) "chlorate reductase C"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.1"^^xsd:string) Annotation( "RHEA:16352"^^xsd:string) "Catalysis of the reaction: AH(2) + chlorate = A + chlorite + H(2)O + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.52"^^xsd:string) "acyl-CoA:2-acyl-sn-glycerol 3-phosphate O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.52"^^xsd:string) Annotation( "GOC:ab"^^xsd:string) Annotation( "MetaCyc:2-ACYL2.3.1.15-RXN"^^xsd:string) Annotation( "RHEA:14236"^^xsd:string) "Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.52"^^xsd:string) "2-acylglycerophosphate acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-acylglycerol-3-phosphate O-acyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.109"^^xsd:string) "demethylsterigmatocystin methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.109"^^xsd:string) Annotation( "MetaCyc:2.1.1.109-RXN"^^xsd:string) "Catalysis of the reaction: 6-demethylsterigmatocystin + S-adenosyl-L-methionine = sterigmatocystin + S-adenosyl-homocysteine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.109"^^xsd:string) "S-adenosyl-L-methionine:6-demethylsterigmatocystin 6-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "demethylsterigmatocystin 6-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.109"^^xsd:string) "O-methyltransferase I"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.110"^^xsd:string) "O-methyltransferase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.110"^^xsd:string) "sterigmatocystin 8-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.110"^^xsd:string) "sterigmatocystin methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sterigmatocystin 7-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.110"^^xsd:string) Annotation( "MetaCyc:2.1.1.110-RXN"^^xsd:string) "Catalysis of the reaction: sterigmatocystin + S-adenosyl-L-methionine = 7-O-methylsterigmatocystin + S-adenosyl-homocysteine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.110"^^xsd:string) "S-adenosyl-L-methionine:sterigmatocystin 8-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.110"^^xsd:string) "S-adenosyl-L-methionine:sterigmatocystin 7-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.19"^^xsd:string) "trimethylsulfonium-tetrahydrofolate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.19"^^xsd:string) "trimethylsulfonium:tetrahydrofolate N-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trimethylsulfonium-tetrahydrofolate N-methyltransferase activity"^^xsd:string) AnnotationAssertion( "trimethylsulphonium-tetrahydrofolate N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.19"^^xsd:string) Annotation( "RHEA:13696"^^xsd:string) "Catalysis of the reaction: (6S)-5,6,7,8-tetrahydrofolate + trimethylsulfonium = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + dimethyl sulfide + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methylamine-glutamate N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.21"^^xsd:string) Annotation( "RHEA:15840"^^xsd:string) "Catalysis of the reaction: L-glutamate + methylammonium = N-methyl-L-glutamate + NH(4)(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.21"^^xsd:string) "methylamine-glutamate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.21"^^xsd:string) "N-methylglutamate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.21"^^xsd:string) "methylamine:L-glutamate N-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.3"^^xsd:string) "thetin-homocysteine methylpherase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.3"^^xsd:string) Annotation( "RHEA:22791"^^xsd:string) "Catalysis of the reaction: L-homocysteine + dimethylsulfonioacetate = (methylthio)acetate + L-methionine + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.3"^^xsd:string) "dimethylsulfonioacetate:L-homocysteine S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.3"^^xsd:string) "dimethylthetin-homocysteine methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thetin-homocysteine S-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.5"^^xsd:string) "trimethylammonioacetate:L-homocysteine S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.5"^^xsd:string) "betaine-homocysteine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.5"^^xsd:string) Annotation( "RHEA:22339"^^xsd:string) "Catalysis of the reaction: L-homocysteine + betaine = N,N-dimethylglycine + L-methionine."^^xsd:string) AnnotationAssertion(rdfs:label "betaine-homocysteine S-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.5"^^xsd:string) "betaine-homocysteine transmethylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.74"^^xsd:string) "methylenetetrahydrofolate-transfer ribonucleate uracil 5-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.74"^^xsd:string) "folate-dependent ribothymidyl synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.74"^^xsd:string) "5,10-methylenetetrahydrofolate:tRNA (uracil-5-)-methyltransferase activity"^^xsd:string) AnnotationAssertion( "methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH-oxidizing) activity"^^xsd:string) AnnotationAssertion(rdfs:label "methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.74"^^xsd:string) "5,10-methylenetetrahydrofolate:tRNA-UPsiC (uracil-5-)-methyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.74"^^xsd:string) Annotation( "MetaCyc:2.1.1.74-RXN"^^xsd:string) "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH + H+ = tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.90"^^xsd:string) "methanol:5-hydroxybenzimidazolylcobamide methyltransferase activity"^^xsd:string) AnnotationAssertion( "methanol:corrinoid methyltransferase activity"^^xsd:string) AnnotationAssertion( "methanol-corrinoid protein Co-methyltransferase."^^xsd:string) AnnotationAssertion(rdfs:label "methanol-5-hydroxybenzimidazolylcobamide Co-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.90"^^xsd:string) "methanol cobalamin methyltransferase activity"^^xsd:string) AnnotationAssertion( "methyltransferase 1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.90"^^xsd:string) Annotation( "MetaCyc:2.1.1.90-RXN"^^xsd:string) "Catalysis of the reaction: 5-hydroxybenzimidazolylcobamide + methanol = H2O + Co-methyl-Co-5-hydroxybenzimidazolylcob(I)amide."^^xsd:string) AnnotationAssertion( "MtaB"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.90"^^xsd:string) "methanol:5-hydroxybenzimidazolylcobamide Co-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.90"^^xsd:string) "MT 1"^^xsd:string) AnnotationAssertion( "MT1"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.2.8"^^xsd:string) Annotation( "RHEA:11283"^^xsd:string) "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + 5-hydroxymethyldeoxycytidylate."^^xsd:string) AnnotationAssertion(rdfs:label "deoxycytidylate 5-hydroxymethyltransferase activity"^^xsd:string) AnnotationAssertion( "deoxycytidylate hydroxymethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.8"^^xsd:string) "deoxycytidylate hydroxymethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.8"^^xsd:string) "dCMP hydroxymethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.8"^^xsd:string) "5,10-methylenetetrahydrofolate:deoxycytidylate 5-hydroxymethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.8"^^xsd:string) "d-cytidine 5'-monophosphate hydroxymethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.8"^^xsd:string) "deoxycytidylic hydroxymethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.8"^^xsd:string) "deoxyCMP hydroxymethylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.3.1"^^xsd:string) "methylmalonyl coenzyme A carboxyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.1"^^xsd:string) "(S)-methylmalonyl-CoA:pyruvate carboxyltransferase activity"^^xsd:string) AnnotationAssertion( "methylmalonyl-CoA carboxyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.1"^^xsd:string) "transcarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.1"^^xsd:string) Annotation( "MetaCyc:2.1.3.1-RXN"^^xsd:string) "Catalysis of the reaction: pyruvate + D-methylmalonyl-CoA = oxaloacetic acid + propionyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.1"^^xsd:string) "methylmalonyl-CoA transcarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.1"^^xsd:string) "oxalacetic transcarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.1"^^xsd:string) "(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.1"^^xsd:string) "(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate"^^xsd:string) AnnotationAssertion(rdfs:label "methylmalonyl-CoA carboxytransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.1"^^xsd:string) "(S)-methylmalonyl-CoA:pyruvate carboxytransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.3.7"^^xsd:string) Annotation( "MetaCyc:2.1.3.7-RXN"^^xsd:string) "Catalysis of the reaction: a 3-hydroxymethylceph-3-em-4-carboxylate + carbamoyl-phosphate = phosphate + a 3-carbamoyloxymethylcephem."^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxymethylcephem carbamoyltransferase activity"^^xsd:string) AnnotationAssertion( "3'-hydroxymethylcephem-O-carbamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.7"^^xsd:string) "carbamoyl-phosphate:3-hydroxymethylceph-3-em-4-carboxylate carbamoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.2.1.4"^^xsd:string) Annotation( "RHEA:21507"^^xsd:string) "Catalysis of the reaction: D-ribose 5-phosphate + acetoin = 1-deoxy-D-altro-heptulose 7-phosphate + acetaldehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.4"^^xsd:string) "1-deoxy-D-altro-heptulose-7-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.4"^^xsd:string) "3-hydroxybutan-3-one:D-ribose-5-phosphate aldehydetransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.4"^^xsd:string) "1-deoxy-D-altro-heptulose-7-phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.4"^^xsd:string) "3-hydroxybutan-2-one:D-ribose-5-phosphate aldehydetransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetoin-ribose-5-phosphate transaldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.100"^^xsd:string) "myelin PLP acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.100"^^xsd:string) Annotation( "MetaCyc:2.3.1.100-RXN"^^xsd:string) "Catalysis of the reaction: [myelin proteolipid] + palmityl-CoA = [myelin proteolipid] O-palmitoylprotein + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.100"^^xsd:string) "[myelin-proteolipid] O-palmitoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.100"^^xsd:string) "acyl-protein synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "myelin-proteolipid O-palmitoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.100"^^xsd:string) "palmitoyl-CoA:[myelin-proteolipid] O-palmitoyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sinapoylglucose-sinapoylglucose O-sinapoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.103"^^xsd:string) "1-(hydroxycinnamoyl)-glucose:1-(hydroxycinnamoyl)-glucose hydroxycinnamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.103"^^xsd:string) "1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)-beta-D-glucoside:1-O-(4-hydroxy-3,5-dimethoxycinnamoyl-beta-D-glucoside 1-O-sinapoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.103"^^xsd:string) Annotation( "RHEA:22667"^^xsd:string) "Catalysis of the reaction: 2 1-O-sinapoyl-beta-D-glucose = 1,2-di-O-sinapoyl-beta-D-glucose + D-glucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.103"^^xsd:string) "hydroxycinnamoylglucose-hydroxycinnamoylglucose hydroxycinnamoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.104"^^xsd:string) Annotation( "MetaCyc:2.3.1.104-RXN"^^xsd:string) "Catalysis of the reaction: 1-alkenylglycerophosphocholine + acyl-CoA = 1-alkenyl-2-acylglycerophosphocholine + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.104"^^xsd:string) "acyl-CoA:1-alkenylglycerophosphocholine O-acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-alkenylglycerophosphocholine O-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.105"^^xsd:string) "acetyl-CoA:1-alkyl-sn-glycero-3-phosphate 2-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.105"^^xsd:string) Annotation( "RHEA:18560"^^xsd:string) "Catalysis of the reaction: 1-alkyl-sn-glycerol 3-phosphate + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.105"^^xsd:string) "alkyllyso-GP:acetyl-CoA acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alkylglycerophosphate 2-O-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tartronate O-hydroxycinnamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.106"^^xsd:string) "sinapoyl-CoA:2-hydroxymalonate O-(hydroxycinnamoyl)transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.106"^^xsd:string) Annotation( "RHEA:10955"^^xsd:string) "Catalysis of the reaction: hydroxymalonate + sinapoyl-CoA = CoA + sinapoyltartronate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.106"^^xsd:string) "hydroxycinnamoyl-coenzyme-A:tartronate hydroxycinnamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.106"^^xsd:string) "tartronate sinapoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.107"^^xsd:string) "acetylcoenzyme A:deacetylvindoline 4-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.107"^^xsd:string) "deacetylvindoline acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.107"^^xsd:string) "acetyl-CoA:deacetylvindoline 4-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.107"^^xsd:string) "acetylcoenzyme A-deacetylvindoline 4-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.107"^^xsd:string) "DAT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.107"^^xsd:string) "acetyl-CoA:17-O-deacetylvindoline 17-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.107"^^xsd:string) "17-O-deacetylvindoline-17-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.107"^^xsd:string) "deacetylvindoline O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.107"^^xsd:string) "acetylcoenzyme A:deacetylvindoline O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.107"^^xsd:string) "acetyl-CoA-17-O-deacetylvindoline 17-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "17-O-deacetylvindoline O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.107"^^xsd:string) Annotation( "RHEA:24499"^^xsd:string) "Catalysis of the reaction: (1R,9R,10S,11R,12R,19R)-12-ethyl-10,11-dihydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + acetyl-CoA = (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-10-hydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.114"^^xsd:string) "malonyl-CoA:3,4-dichloroaniline N-malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.114"^^xsd:string) Annotation( "RHEA:21063"^^xsd:string) "Catalysis of the reaction: 3,4-dichloroaniline + malonyl-CoA = N-(3,4-dichlorophenyl)malonamate + CoA."^^xsd:string) AnnotationAssertion(rdfs:label "3,4-dichloroaniline N-malonyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.115"^^xsd:string) Annotation( "MetaCyc:2.3.1.115-RXN"^^xsd:string) "Catalysis of the reaction: biochanin-A + malonyl-CoA = 6'-malonyl-biochanin A + CoA."^^xsd:string) AnnotationAssertion(rdfs:label "isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.115"^^xsd:string) "flavone (flavonol) 7-O-glycoside malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.115"^^xsd:string) "malonyl-coenzyme A:flavone/flavonol-7-O-glycoside malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.115"^^xsd:string) "flavone/flavonol 7-O-beta-D-glucoside malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.115"^^xsd:string) "malonyl-CoA:flavone/flavonol 7-O-glucoside malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.115"^^xsd:string) "malonyl-CoA:isoflavone-7-O-beta-D-glucoside 6''-O-malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.115"^^xsd:string) "malonyl-coenzyme A:isoflavone 7-O-glucoside-6''-malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.115"^^xsd:string) "MAT-7"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "flavonol-3-O-beta-glucoside O-malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.116"^^xsd:string) Annotation( "MetaCyc:2.3.1.116-RXN"^^xsd:string) "Catalysis of the reaction: flavonol 3-O-beta-D-glucoside + malonyl-CoA = malonyl-flavonol 3-O-beta-D-glucoside + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.116"^^xsd:string) "malonyl-coenzyme A:flavonol-3-O-glucoside malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.116"^^xsd:string) "malonyl-CoA:flavonol-3-O-beta-D-glucoside 6''-O-malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.116"^^xsd:string) "flavonol 3-O-glucoside malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.116"^^xsd:string) "MAT-3"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.121"^^xsd:string) "acyl-CoA:1-alkenylglycerophosphoethanolamine O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.121"^^xsd:string) Annotation( "MetaCyc:2.3.1.121-RXN"^^xsd:string) "Catalysis of the reaction: 1-alkenylglycerophosphoethanolamine + acyl-CoA = 1-alkenyl-2-acyl-glycerophosphoethanolamine + CoA."^^xsd:string) AnnotationAssertion(rdfs:label "1-alkenylglycerophosphoethanolamine O-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1-alkyl-2-acetylglycerol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.125"^^xsd:string) "1-hexadecyl-2-acetylglycerol acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.125"^^xsd:string) "acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.125"^^xsd:string) Annotation( "MetaCyc:2.3.1.125-RXN"^^xsd:string) "Catalysis of the reaction: 1-O-alkyl-2-acetyl-sn-glycerol + acyl-CoA = 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.126"^^xsd:string) Annotation( "RHEA:20759"^^xsd:string) "Catalysis of the reaction: caffeoyl-CoA + isocitrate = 2-caffeoylisocitrate + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.126"^^xsd:string) "caffeoyl-CoA:isocitrate 3-O-(3,4-dihydroxycinnamoyl)transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "isocitrate O-dihydroxycinnamoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.130"^^xsd:string) Annotation( "RHEA:13000"^^xsd:string) "Catalysis of the reaction: feruloyl-CoA + galactarate = 2-(E)-O-feruloyl-D-galactarate + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.130"^^xsd:string) "galacturate hydroxycinnamoyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactarate O-hydroxycinnamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.130"^^xsd:string) "feruloyl-CoA:galactarate O-(hydroxycinnamoyl)transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.131"^^xsd:string) Annotation( "RHEA:23311"^^xsd:string) "Catalysis of the reaction: D-glucarate + sinapoyl-CoA = 2-O-sinapoyl-D-glucarate + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.131"^^xsd:string) "sinapoyl-CoA:glucarate O-(hydroxycinnamoyl)transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucarate O-hydroxycinnamoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucarolactone O-hydroxycinnamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.132"^^xsd:string) Annotation( "MetaCyc:2.3.1.132-RXN"^^xsd:string) "Catalysis of the reaction: glucarolactone + sinapoyl-CoA = O-sinapoylglucarolactone + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.132"^^xsd:string) "sinapoyl-CoA:glucarolactone O-(hydroxycinnamoyl)transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.133"^^xsd:string) "4-coumaroyl-CoA:shikimate O-(hydroxycinnamoyl)transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "shikimate O-hydroxycinnamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.133"^^xsd:string) Annotation( "MetaCyc:2.3.1.133-RXN"^^xsd:string) "Catalysis of the reaction: shikimate + coumaroyl-CoA = 4-coumaroylshikimate + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.133"^^xsd:string) "shikimate hydroxycinnamoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.135"^^xsd:string) Annotation( "MetaCyc:2.3.1.135-RXN"^^xsd:string) "Catalysis of the reaction: retinol-[cellular-retinol-binding-protein] + phosphatidylcholine = retinyl-ester-[cellular-retinol-binding-protein] + 2-acylglycerophosphocholine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.135"^^xsd:string) "phosphatidylcholine:retinol-(cellular-retinol-binding-protein) O-acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylcholine-retinol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.135"^^xsd:string) "phosphatidylcholine:retinol-[cellular-retinol-binding-protein] O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.135"^^xsd:string) "lecithin--retinol acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.138"^^xsd:string) "putrescine hydroxycinnamoyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.138"^^xsd:string) "putrescine hydroxycinnamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.138"^^xsd:string) Annotation( "RHEA:12439"^^xsd:string) "Catalysis of the reaction: caffeoyl-CoA + putrescine = N-caffeoylputrescine + CoA + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.138"^^xsd:string) "PHT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.138"^^xsd:string) "caffeoyl-CoA:putrescine N-(3,4-dihydroxycinnamoyl)transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.138"^^xsd:string) "hydroxycinnamoyl-CoA:putrescine hydroxycinnamoyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "putrescine N-hydroxycinnamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.138"^^xsd:string) "caffeoyl-CoA putrescine N-caffeoyl transferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.141"^^xsd:string) Annotation( "MetaCyc:2.3.1.141-RXN"^^xsd:string) "Catalysis of the reaction: sn-3-D-galactosyl-sn-2-acylglycerol + acyl-[acyl-carrier protein] = D-galactosyldiacylglycerol + [acyl-carrier protein]."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.141"^^xsd:string) "acyl-acyl-carrier protein: lysomonogalactosyldiacylglycerol acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactosylacylglycerol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.141"^^xsd:string) "acyl-acyl-carrier-protein:D-galactosylacylglycerol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.141"^^xsd:string) "acyl-ACP:lyso-MGDG acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-glucogallin-tetrakisgalloylglucose O-galloyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.143"^^xsd:string) "beta-glucogallin-tetragalloylglucose 4-galloyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.143"^^xsd:string) "beta-glucogallin:1,2,3,6-tetra-O-galloyl-beta-D-glucose 4-O-galloyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.143"^^xsd:string) "1-O-galloyl-beta-D-glucose:1,2,3,6-tetrakis-O-galloyl-beta-D-glucose 4-O-galloyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.143"^^xsd:string) "beta-glucogallin:1,2,3,6-tetra-O-galloylglucose 4-O-galloyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.143"^^xsd:string) Annotation( "RHEA:19112"^^xsd:string) "Catalysis of the reaction: 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose + 1-O-galloyl-beta-D-glucose = 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + D-glucose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.147"^^xsd:string) "1-organyl-2-arachidonyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine arachidonoyltransferase (CoA-independent)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.147"^^xsd:string) "1-organyl-2-arachidonoyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine arachidonoyltransferase (CoA-independent)"^^xsd:string) AnnotationAssertion(rdfs:label "glycerophospholipid arachidonoyl-transferase (CoA-independent) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.147"^^xsd:string) Annotation( "MetaCyc:2.3.1.147-RXN"^^xsd:string) "Catalysis of the reaction: 1-alkyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphoethanolamine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycerophospholipid acyltransferase (CoA-dependent) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.148"^^xsd:string) "1-organyl-2-acyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine acyltransferase (CoA-dependent)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.148"^^xsd:string) Annotation( "MetaCyc:2.3.1.148-RXN"^^xsd:string) "Catalysis of the reaction: 1-radyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-radyl-2-acyl-sn-glycero-3-phosphocholine = 1-radyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acyl-sn-glycero-3-phosphoethanolamine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "platelet-activating factor acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.149"^^xsd:string) Annotation( "MetaCyc:2.3.1.149-RXN"^^xsd:string) "Catalysis of the reaction: 1-radyl-2-acyl-sn-glycero-3-phospholipid + 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acetyl-sn-glycero-3-phospholipid."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.149"^^xsd:string) "1-alkyl-2-acyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phospholipid acetyltransferase activity"^^xsd:string) AnnotationAssertion( "PAF acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.150"^^xsd:string) Annotation( "RHEA:22859"^^xsd:string) "Catalysis of the reaction: (7S)-salutaridinol + acetyl-CoA = (7S)-O-acetylsalutaridinol + CoA."^^xsd:string) AnnotationAssertion(rdfs:label "salutaridinol 7-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.150"^^xsd:string) "acetyl-CoA:salutaridinol 7-O-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "benzophenone synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.151"^^xsd:string) "malonyl-CoA:3-hydroxybenzoyl-CoA malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.151"^^xsd:string) Annotation( "MetaCyc:2.3.1.151-RXN"^^xsd:string) "Catalysis of the reaction: 3-hydroxybenzoyl-CoA + 3 malonyl-CoA = 3 CO2 + 2,3',4,6-tetrahydroxybenzophenone + 4 coenzyme A."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.152"^^xsd:string) "1-O-trans-cinnamoyl-beta-D-glucopyranose:alcohol O-cinnamoyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alcohol O-cinnamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.152"^^xsd:string) Annotation( "MetaCyc:2.3.1.152-RXN"^^xsd:string) "Catalysis of the reaction: an alcohol + 1-O-trans-cinnamoyl-beta-D-glucopyranose = beta-D-glucose + alkyl cinnamate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.153"^^xsd:string) Annotation( "MetaCyc:2.3.1.153-RXN"^^xsd:string) "Catalysis of the reaction: anthocyanidin-3,5-diglucoside + hydroxycinnamoyl-CoA = anthocyanidin 3-glucoside-5-hydroxycinnamoylglucoside + CoA."^^xsd:string) AnnotationAssertion(rdfs:label "anthocyanin 5-aromatic acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.153"^^xsd:string) "hydroxycinnamoyl-CoA:anthocyanidin 3,5-diglucoside 5-O-glucoside-6'''-O-hydroxycinnamoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.23"^^xsd:string) "lysophosphatidylcholine acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.23"^^xsd:string) "acyl coenzyme A-monoacylphosphatidylcholine acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.23"^^xsd:string) "acyl-CoA:1-acyl-glycero-3-phosphocholine transacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.23"^^xsd:string) "lysolecithin acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-acylglycerophosphocholine O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.23"^^xsd:string) "acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.23"^^xsd:string) Annotation( "MetaCyc:2.3.1.23-RXN"^^xsd:string) "Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.23"^^xsd:string) "1-acyl-sn-glycero-3-phosphocholine acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.23"^^xsd:string) "lysophosphatide acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.44"^^xsd:string) "sialate O-acetyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.44"^^xsd:string) Annotation( "RHEA:18308"^^xsd:string) "Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-4-O-acetylneuraminate + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.44"^^xsd:string) "acetyl-CoA:N-acetylneuraminate 4-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylneuraminate 4-O-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.45"^^xsd:string) "N-acetylneuraminate 7(8)-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.45"^^xsd:string) "N-acetylneuraminate O7-(or O9-)acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.45"^^xsd:string) "sialate O-acetyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.45"^^xsd:string) Annotation( "MetaCyc:2.3.1.45-RXN"^^xsd:string) "Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-7-O(or 9-O)-acetylneuraminate + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.45"^^xsd:string) "acetyl-CoA:N-acetylneuraminate-9(or 7)-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.45"^^xsd:string) "acetyl-CoA:N-acetylneuraminate-9(7)-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.45"^^xsd:string) "N-acetylneuraminate 7,8-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.45"^^xsd:string) "acetyl-CoA:N-acetylneuraminate-7- or 8-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.45"^^xsd:string) "acetyl-CoA:N-acetylneuraminate-7- and/or 8-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.45"^^xsd:string) "acetyl-CoA:N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.45"^^xsd:string) "glycoprotein 7(9)-O-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.49"^^xsd:string) "S-acetyl phosphopantetheine:deacetyl citrate lyase S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.49"^^xsd:string) Annotation( "MetaCyc:2.3.1.49-RXN"^^xsd:string) "Catalysis of the reaction: deacetyl-[citrate-oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + S-acetylphosphopantetheine = [citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + pantetheine 4'-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.49"^^xsd:string) "deacetyl-citrate-(pro-3S)-lyase acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.49"^^xsd:string) "deacetyl-citrate-(pro-3S)-lyase S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.49"^^xsd:string) "S-acetylphosphopantetheine:deacetyl-citrate-oxaloacetate-lyase((pro-3S)-CH2COO-rightacetate)S-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.56"^^xsd:string) "N-hydroxy-2-acetylaminofluorene N-O acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.56"^^xsd:string) "arylhydroxamic acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.56"^^xsd:string) "arylhydroxamic acid N,O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.56"^^xsd:string) "aromatic hydroxylamine acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.56"^^xsd:string) Annotation( "MetaCyc:2.3.1.56-RXN"^^xsd:string) "Catalysis of the reaction: N-hydroxy-4-aminobiphenyl + N-hydroxy-4-acetylaminonbiphenyl = N-acetoxy-4-aminobiphenyl + N-hydroxy-4-aminobiphenyl."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.56"^^xsd:string) "N-hydroxy-4-acetylaminobiphenyl:N-hydroxy-4-aminobiphenyl O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aromatic-hydroxylamine O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.56"^^xsd:string) "N,O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.56"^^xsd:string) "arylhydroxamate acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,3-diaminopropionate N-oxalyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.58"^^xsd:string) "oxalyl-CoA:L-2,3-diaminopropanoate N3-oxalyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.58"^^xsd:string) "oxalyldiaminopropionate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.58"^^xsd:string) "oxalyl-CoA:L-alpha,beta-diaminopropionic acid oxalyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.58"^^xsd:string) "oxalyl-CoA:L-2,3-diaminopropanoate 3-N-oxalyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.58"^^xsd:string) "ODAP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.58"^^xsd:string) "oxalyldiaminopropionic synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.58"^^xsd:string) Annotation( "RHEA:13468"^^xsd:string) "Catalysis of the reaction: 3-amino-L-alanine + oxalyl-CoA = N(3)-oxalyl-L-2,3-diaminopropanoate + CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.62"^^xsd:string) "2-acylglycerophosphocholine acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.62"^^xsd:string) "2-acylglycerol-3-phosphorylcholine acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-acylglycerophosphocholine O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.62"^^xsd:string) "acyl-CoA:2-acyl-sn-glycero-3-phosphocholine O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.62"^^xsd:string) Annotation( "RHEA:10335"^^xsd:string) "Catalysis of the reaction: 2-acyl-sn-glycero-3-phosphocholine + acyl-CoA = 1,2-diacyl-sn-glycero-3-phosphocholine + CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1-alkylglycerophosphocholine O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.63"^^xsd:string) Annotation( "MetaCyc:2.3.1.63-RXN"^^xsd:string) "Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acyl-CoA = 1-alkyl-2-acyl-sn-glycero-3-phosphocholine + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.63"^^xsd:string) "acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.67"^^xsd:string) "lysoPAF:acetyl CoA acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.67"^^xsd:string) "blood platelet-activating factor acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.67"^^xsd:string) "lyso-platelet-activating factor:acetyl-CoA acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.67"^^xsd:string) "lysopaf:acetyl CoA acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-alkylglycerophosphocholine O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.67"^^xsd:string) "platelet-activating factor acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.67"^^xsd:string) "acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine 2-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.67"^^xsd:string) Annotation( "MetaCyc:2.3.1.67-RXN"^^xsd:string) "Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.67"^^xsd:string) "acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.67"^^xsd:string) "1-alkyl-2-lysolecithin acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.67"^^xsd:string) "1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.67"^^xsd:string) "acetyl-CoA:lyso-PAF acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.67"^^xsd:string) "lyso-platelet activating factor:acetyl-CoA acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.67"^^xsd:string) "platelet-activating factor-synthesizing enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.67"^^xsd:string) "lyso-GPC:acetyl CoA acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.67"^^xsd:string) "acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine 2-O-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "indoleacetylglucose-inositol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.72"^^xsd:string) "1-O-(indol-3-yl)acetyl-beta-D-glucose:myo-inositol (indol-3-yl)acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.72"^^xsd:string) "1-O-(indol-3-ylacetyl)-beta-D-glucose:myo-inositol indole-3-ylacetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.72"^^xsd:string) Annotation( "RHEA:21183"^^xsd:string) "Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + myo-inositol = 1L-1-O-(indol-3-yl)acetyl-myo-inositol + D-glucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.72"^^xsd:string) "indole-3-acetyl-beta-1-D-glucoside:myo-inositol indoleacetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "diacylglycerol-sterol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.73"^^xsd:string) "1,2-diacyl-sn-glycerol:sterol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.73"^^xsd:string) "1,2-diacyl-sn-glycerol:sterol acyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.73"^^xsd:string) Annotation( "MetaCyc:2.3.1.73-RXN"^^xsd:string) "Catalysis of the reaction: sterol + 1,2-diacylglycerol = sterol ester + acylglycerol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "long-chain-alcohol O-fatty-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.75"^^xsd:string) "wax synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.75"^^xsd:string) "wax-ester synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.75"^^xsd:string) "acyl-CoA:long-chain-alcohol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.75"^^xsd:string) Annotation( "MetaCyc:2.3.1.75-RXN"^^xsd:string) "Catalysis of the reaction: a long-chain-alcohol + acyl-CoA = a long-chain ester + CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "triglyceride-sterol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.77"^^xsd:string) "triacylglycerol:3beta-hydroxysterol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.77"^^xsd:string) "triacylglycerol:sterol acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.77"^^xsd:string) Annotation( "MetaCyc:2.3.1.77-RXN"^^xsd:string) "Catalysis of the reaction: a 3-beta-hydroxysterol + triacylglycerol = a 3-beta-hydroxysterol ester + 1,2-diacylglycerol."^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "triacylglycerol-sterol O-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.80"^^xsd:string) Annotation( "RHEA:19216"^^xsd:string) "Catalysis of the reaction: S-substituted L-cysteine + acetyl-CoA = S-substituted N-acetyl-L-cysteine + CoA + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "cysteine-S-conjugate N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.80"^^xsd:string) "acetyl-CoA:S-substituted L-cysteine N-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.83"^^xsd:string) Annotation( "RHEA:19288"^^xsd:string) "Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + dolichol = 1-acyl-sn-glycero-3-phosphocholine + acyldolichol."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.83"^^xsd:string) "3-sn-phosphatidylcholine:dolichol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylcholine-dolichol O-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.89"^^xsd:string) "tetrahydrodipicolinate acetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.89"^^xsd:string) "tetrahydrodipicolinate:acetyl-CoA acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tetrahydrodipicolinate N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.89"^^xsd:string) "acetyl-CoA:(S)-2,3,4,5-tetrahydrodipicolinate-2,6-dicarboxylate N2-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.89"^^xsd:string) "acetyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate 2-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.89"^^xsd:string) "acetyl-CoA:L-2,3,4,5-tetrahydrodipicolinate N2-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.89"^^xsd:string) Annotation( "RHEA:13088"^^xsd:string) "Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H(2)O = L-2-acetamido-6-oxopimelate + CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.90"^^xsd:string) Annotation( "RHEA:11419"^^xsd:string) "Catalysis of the reaction: 2 1-O-galloyl-beta-D-glucose = 1,6-bis-O-galloyl-beta-D-glucose + D-glucose."^^xsd:string) AnnotationAssertion(rdfs:label "beta-glucogallin O-galloyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.90"^^xsd:string) "1-O-galloyl-beta-D-glucose:1-O-galloyl-beta-D-glucose O-galloyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.91"^^xsd:string) Annotation( "RHEA:12027"^^xsd:string) "Catalysis of the reaction: 1-O-sinapoyl-beta-D-glucose + choline = O-sinapoylcholine + D-glucose."^^xsd:string) AnnotationAssertion(rdfs:label "sinapoylglucose-choline O-sinapoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.91"^^xsd:string) "1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)-beta-D-glucose:choline 1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.91"^^xsd:string) "sinapine synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.93"^^xsd:string) "13-hydroxylupanine acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.93"^^xsd:string) "tigloyl-CoA:13-hydroxylupanine O-tigloyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.93"^^xsd:string) Annotation( "RHEA:12363"^^xsd:string) "Catalysis of the reaction: 13-hydroxylupanine + 2-methylcrotonoyl-CoA = 13-(2-methylcrotonoyloxy)lupanine + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.93"^^xsd:string) "(E)-2-methylcrotonoyl-CoA:13-hydroxylupinine O-2-methylcrotonoyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "13-hydroxylupinine O-tigloyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chlorogenate-glucarate O-hydroxycinnamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.98"^^xsd:string) "chlorogenic acid:glucaric acid O-caffeoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.98"^^xsd:string) "chlorogenate:glucarate O-(hydroxycinnamoyl)transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.98"^^xsd:string) "chlorogenate:glucarate caffeoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.98"^^xsd:string) Annotation( "RHEA:23207"^^xsd:string) "Catalysis of the reaction: D-glucarate + chlorogenate = (-)-quinate + 2-O-caffeoylglucarate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "quinate O-hydroxycinnamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.99"^^xsd:string) "feruloyl-CoA:quinate O-(hydroxycinnamoyl)transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.99"^^xsd:string) "hydroxycinnamoyl coenzyme A-quinate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.99"^^xsd:string) Annotation( "MetaCyc:2.3.1.99-RXN"^^xsd:string) "Catalysis of the reaction: feruloyl-CoA + quinate = O-feruloylquinate + CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.2.10"^^xsd:string) "UDP-N-acetylmuramoylpentapeptide lysine N(6)-alanyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.10"^^xsd:string) "alanyl-transfer ribonucleate-uridine diphosphoacetylmuramoylpentapeptide transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.10"^^xsd:string) "L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine 6-N-alanyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.10"^^xsd:string) "UDP-N-acetylmuramoylpentapeptide lysine N6-alanyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.10"^^xsd:string) "L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine N6-alanyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.10"^^xsd:string) Annotation( "MetaCyc:2.3.2.10-RXN"^^xsd:string) "Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-alanyl-tRNA = UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.10"^^xsd:string) "uridine diphosphoacetylmuramoylpentapeptide lysine N(6)-alanyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.10"^^xsd:string) "uridine diphosphoacetylmuramoylpentapeptide lysine N6-alanyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.100"^^xsd:string) "1,2-beta-D-fructan:1,2-beta-D-fructan 1F-beta-D-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.100"^^xsd:string) "2,1-fructan:2,1-fructan 1-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.100"^^xsd:string) "fructan:fructan fructosyl transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1,2-beta-fructan 1F-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.100"^^xsd:string) "1,2-beta-fructan 1(F)-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.100"^^xsd:string) "2,1-beta-D-fructan:2,1-beta-D-fructan 1-beta-D-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.100"^^xsd:string) "1,2-beta-D-fructan 1(F)-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.100"^^xsd:string) "FFT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.100"^^xsd:string) Annotation( "MetaCyc:2.4.1.100-RXN"^^xsd:string) "Catalysis of the reaction: [(1->2)-beta-D-fructosyl](n) + [(1->2)-beta-D-fructosyl](m) = [(1->2)-beta-D-fructosyl](n+1) + [(1->2)-beta-D-fructosyl](m-1)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.100"^^xsd:string) "1,2-beta-D-fructan:1,2-beta-D-fructan 1(F)-beta-D-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.100"^^xsd:string) "1,2-beta-D-fructan 1F-fructosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.104"^^xsd:string) "UDPglucose:7,8-dihydroxycoumarin 7-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.104"^^xsd:string) "UDP-glucose:7,8-dihydroxycoumarin 7-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.104"^^xsd:string) Annotation( "RHEA:14328"^^xsd:string) "Catalysis of the reaction: 7,8-dihydroxycoumarin + UDP-D-glucose = daphnin + H(+) + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.104"^^xsd:string) "uridine diphosphoglucose-o-dihydroxycoumarin 7-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.104"^^xsd:string) "UDP-glucose:o-dihydroxycoumarin glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "o-dihydroxycoumarin 7-O-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.111"^^xsd:string) Annotation( "MetaCyc:2.4.1.111-RXN"^^xsd:string) "Catalysis of the reaction: coniferyl alcohol + UDP-D-glucose = coniferin + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.111"^^xsd:string) "UDP-glucose coniferyl alcohol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.111"^^xsd:string) "UDPglucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.111"^^xsd:string) "UDP-glucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.111"^^xsd:string) "uridine diphosphoglucose-coniferyl alcohol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "coniferyl-alcohol glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.113"^^xsd:string) "adenosine diphosphoglucose-protein glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.113"^^xsd:string) "ADP-glucose:protein 4-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.113"^^xsd:string) Annotation( "MetaCyc:2.4.1.113-RXN"^^xsd:string) "Catalysis of the reaction: ADP-D-glucose + protein = alpha-D-glucosyl-protein + ADP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.113"^^xsd:string) "ADPglucose:protein 4-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-1,4-glucan-protein synthase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.113"^^xsd:string) "ADPglucose:protein glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "1,4alpha-glucan-protein synthase (ADP-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.114"^^xsd:string) "uridine diphosphoglucose-o-coumarate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.114"^^xsd:string) "UDPglucose:trans-2-hydroxycinnamate O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-coumarate O-beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.114"^^xsd:string) Annotation( "RHEA:10239"^^xsd:string) "Catalysis of the reaction: trans-2-coumarate + UDP-D-glucose = trans-beta-D-glucosyl-2-hydroxycinnamate + H(+) + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.114"^^xsd:string) "UDP-glucose:trans-2-hydroxycinnamate O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.114"^^xsd:string) "UDPG:o-coumaric acid O-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.115"^^xsd:string) "UDP-D-glucose:anthocyanidin 3-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.115"^^xsd:string) Annotation( "MetaCyc:2.4.1.115-RXN"^^xsd:string) "Catalysis of the reaction: anthocyanidin + UDP-D-glucose = anthocyanidin-3-O-D-glucoside + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.115"^^xsd:string) "3-GT activity"^^xsd:string) AnnotationAssertion(rdfs:label "anthocyanidin 3-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.115"^^xsd:string) "UDP-glucose:cyanidin-3-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.115"^^xsd:string) "UDP-glucose:anthocyanidin/flavonol 3-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.115"^^xsd:string) "uridine diphosphoglucose-anthocyanidin 3-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.115"^^xsd:string) "UDP-glucose:anthocyanidin 3-O-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.116"^^xsd:string) "UDP-glucose:cyanidin-3-O-D-rhamnosyl-1,6-D-glucoside 5-O-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyanidin-3-rhamnosylglucoside 5-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.116"^^xsd:string) Annotation( "MetaCyc:2.4.1.116-RXN"^^xsd:string) "Catalysis of the reaction: cyanidin-3-O-D-rhamnosyl-(1,6)-D-glucoside + UDP-D-glucose = cyanidin-3-O-[D-rhamnosyl-(1,6)-D-glucoside]-5-O-D-glucoside + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.116"^^xsd:string) "UDP-glucose:cyanidin-3-O-beta-L-rhamnosyl-(1->6)-beta-D-glucoside 5-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.116"^^xsd:string) "cyanidin-3-O-rutinoside 5-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.116"^^xsd:string) "uridine diphosphoglucose-cyanidin 3-rhamnosylglucoside 5-O-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.121"^^xsd:string) "UDP-glucose:indol-3-ylacetate glucosyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.121"^^xsd:string) "IAA-glucose synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.121"^^xsd:string) "UDP-glucose:indol-3-ylacetate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.121"^^xsd:string) Annotation( "RHEA:14924"^^xsd:string) "Catalysis of the reaction: (indol-3-yl)acetate + UDP-D-glucose = 1-O-(indol-3-ylacetyl)-beta-D-glucose + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.121"^^xsd:string) "UDPglucose:indole-3-acetate beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "indole-3-acetate beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.121"^^xsd:string) "IAGlu synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.121"^^xsd:string) "uridine diphosphoglucose-indoleacetate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.121"^^xsd:string) "indol-3-ylacetylglucose synthase activity"^^xsd:string) AnnotationAssertion( "UDP-glucose:indol-3-acetic acid glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.121"^^xsd:string) "IAA-Glu synthetase activity"^^xsd:string) AnnotationAssertion( "UDP-glucose:auxin glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.121"^^xsd:string) "UDPG-indol-3-ylacetyl glucosyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.121"^^xsd:string) "UDP-glucose:(indol-3-yl)acetate beta-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol 3-alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.123"^^xsd:string) "UDP-galactose:myo-inositol 1-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.123"^^xsd:string) "UDP-D-galactose:inositol galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.123"^^xsd:string) "UDPgalactose:myo-inositol 1-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "inositol 1-alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.123"^^xsd:string) "UDP-galactose:myo-inositol 3-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.123"^^xsd:string) "uridine diphosphogalactose-inositol galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.123"^^xsd:string) "galactinol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.123"^^xsd:string) Annotation( "MetaCyc:2.4.1.123-RXN"^^xsd:string) "Catalysis of the reaction: myo-inositol + UDP-galactose = O-alpha-D-galactosyl-(1,3)-1D-myo-inositol + UDP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.125"^^xsd:string) "GTF-S"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.125"^^xsd:string) Annotation( "MetaCyc:2.4.1.125-RXN"^^xsd:string) "Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = 1,6-alpha-D-glucosyl(n+1) + fructose."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.125"^^xsd:string) "water-soluble-glucan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.125"^^xsd:string) "sucrose:1,6-alpha-D-glucan 3(6)-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.125"^^xsd:string) "sucrose:1,6-alpha-D-glucan 3-alpha- and 6-alpha-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sucrose-1,6-alpha-glucan 3(6)-alpha-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.125"^^xsd:string) "sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and 6-alpha-D-glucosyltransferase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.126"^^xsd:string) Annotation( "MetaCyc:2.4.1.126-RXN"^^xsd:string) "Catalysis of the reaction: 4-coumarate + UDP-D-glucose = 4-O-beta-D-glucosyl-4-hydroxycinnamate + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.126"^^xsd:string) "hydroxycinnamoyl glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.126"^^xsd:string) "UDPglucose:trans-4-hydroxycinnamate 4-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydroxycinnamate 4-beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.126"^^xsd:string) "UDP-glucose-hydroxycinnamate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.126"^^xsd:string) "uridine diphosphoglucose-hydroxycinnamate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.126"^^xsd:string) "UDP-glucose:trans-4-hydroxycinnamate 4-O-beta-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.127"^^xsd:string) "UDP-glucose:(-)-menthol O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "monoterpenol beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.127"^^xsd:string) Annotation( "RHEA:11523"^^xsd:string) "Catalysis of the reaction: (-)-menthol + UDP-D-glucose = (-)-menthyl beta-D-glucoside + H(+) + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.127"^^xsd:string) "uridine diphosphoglucose-monoterpenol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.127"^^xsd:string) "UDPglucose:monoterpenol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.127"^^xsd:string) "UDPglucose:(-)-menthol O-beta-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.134"^^xsd:string) "uridine diphosphogalactose-galactosylxylose galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.134"^^xsd:string) "galactosyltransferase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.134"^^xsd:string) "UDPgalactose:4-beta-D-galactosyl-O-beta-D-xylosylprotein 3-beta-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.134"^^xsd:string) Annotation( "MetaCyc:2.4.1.134-RXN"^^xsd:string) "Catalysis of the reaction: 4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP-galactose = 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.134"^^xsd:string) "UDP-galactose:4-beta-D-galactosyl-O-beta-D-xylosylprotein 3-beta-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactosylxylosylprotein 3-beta-galactosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.137"^^xsd:string) "FPS"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.137"^^xsd:string) Annotation( "RHEA:14288"^^xsd:string) "Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate + H(+) + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.137"^^xsd:string) "UDP-galactose:sn-glycerol-3-phosphate 2-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.137"^^xsd:string) "UDP-galactose:sn-glycerol-3-phosphate-2-D-galactosyl transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sn-glycerol-3-phosphate 2-alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.137"^^xsd:string) "UDPgalactose:sn-glycerol-3-phosphate 2-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.137"^^xsd:string) "floridoside-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.137"^^xsd:string) "floridoside phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.137"^^xsd:string) "floridoside phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.137"^^xsd:string) "UDP-galactose, sn-3-glycerol phosphate:1->2' galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mannotetraose 2-alpha-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.138"^^xsd:string) "alpha-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.138"^^xsd:string) "UDP-N-acetyl-D-glucosamine:mannotetraose alpha-N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.138"^^xsd:string) Annotation( "MetaCyc:2.4.1.138-RXN"^^xsd:string) "Catalysis of the reaction: 1,3-alpha-D-mannosyl-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose + UDP-N-acetyl-D-glucosamine = 1,3-alpha-D-mannosyl-1,2-(N-acetyl-alpha-D-glucosaminyl-alpha-D-mannosyl)-1,2-alpha-D-mannosyl-D-mannose + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.138"^^xsd:string) "uridine diphosphoacetylglucosamine mannoside alpha1->2-alphacetylglucosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.146"^^xsd:string) Annotation( "MetaCyc:2.4.1.146-RXN"^^xsd:string) "Catalysis of the reaction: beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.146"^^xsd:string) "elongation 3beta-GalNAc-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.146"^^xsd:string) "O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.146"^^xsd:string) "UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to -D-galactose of beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R) beta-1,3-N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.146"^^xsd:string) "uridine diphosphoacetylglucosamine-mucin beta(1->3)-acetylglucosaminyltransferase (elongating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.146"^^xsd:string) "elongation 3-beta-GalNAc-transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.147"^^xsd:string) "UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosaminyl-R) beta-1,3-N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.147"^^xsd:string) "O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.147"^^xsd:string) "core 3-beta-GlcNAc-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.147"^^xsd:string) Annotation( "MetaCyc:2.4.1.147-RXN"^^xsd:string) "Catalysis of the reaction: N-acetyl-D-galactosalaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.147"^^xsd:string) "core 3beta-GlcNAc-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.147"^^xsd:string) "uridine diphosphoacetylglucosamine-mucin beta(1->3)-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.147"^^xsd:string) "mucin core 3 beta3-GlcNAc-transferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.148"^^xsd:string) "core 6beta-GalNAc-transferase B"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.148"^^xsd:string) "core 4 beta6-GalNAc-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.148"^^xsd:string) "core 6-beta-GalNAc-transferase B activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.148"^^xsd:string) "UDP-N-acetyl-D-glucosamine:O-oligosaccharide-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.148"^^xsd:string) "O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.148"^^xsd:string) Annotation( "MetaCyc:2.4.1.148-RXN"^^xsd:string) "Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-D-galactosaminyl-R + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.148"^^xsd:string) "uridine diphosphoacetylglucosamine-mucin beta(1->6)-acetylglucosaminyltransferase B"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.156"^^xsd:string) "UDP-galactose:indol-3-ylacetyl-myo-inositol 5-O-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "indolylacetyl-myo-inositol galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.156"^^xsd:string) Annotation( "RHEA:21151"^^xsd:string) "Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-D-galactose = 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H(+) + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.156"^^xsd:string) "indol-3-ylacetyl-myo-inositol galactoside synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.156"^^xsd:string) "UDP-galactose:(indol-3-yl)acetyl-myo-inositol 5-O-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.156"^^xsd:string) "uridine diphosphogalactose-indolylacetylinositol galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.157"^^xsd:string) "UDP-glucose-diacylglycerol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.157"^^xsd:string) "UDP-glucose:1,2-diacylglycerol 3-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.157"^^xsd:string) "uridine diphosphoglucose-diacylglycerol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.157"^^xsd:string) "UDP-glucose:1,2-diacylglycerol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.157"^^xsd:string) "UDPglucose:diacylglycerol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.157"^^xsd:string) Annotation( "MetaCyc:2.4.1.157-RXN"^^xsd:string) "Catalysis of the reaction: 1,2-diacylglycerol + UDP-D-glucose = 3-D-glucosyl-1,2-diacylglycerol + UDP."^^xsd:string) AnnotationAssertion(rdfs:label "1,2-diacylglycerol 3-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.157"^^xsd:string) "UDPglucose:1,2-diacylglycerol 3-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.158"^^xsd:string) "UDP-glucose:13-hydroxydocosanoic acid glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.158"^^xsd:string) "UDP-glucose:13-hydroxydocosanoate 13-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "13-hydroxydocosanoate 13-beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.158"^^xsd:string) "UDPglucose:13-hydroxydocosanoate 13-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.158"^^xsd:string) Annotation( "MetaCyc:2.4.1.158-RXN"^^xsd:string) "Catalysis of the reaction: 13-hydroxydocosanoate + UDP-D-glucose = 13-beta-D-glucosyloxydocosanoate + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.158"^^xsd:string) "uridine diphosphoglucose-hydroxydocosanoate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.158"^^xsd:string) "UDP-glucose-13-hydroxydocosanoate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.158"^^xsd:string) "13-glucosyloxydocosanoate 2'-beta-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.159"^^xsd:string) "UDP-rhamnose:flavonol 3-O-glucoside rhamnosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "flavonol-3-O-glucoside L-rhamnosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.159"^^xsd:string) "UDP-L-rhamnose:flavonol-3-O-D-glucoside 6''-O-L-rhamnosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.159"^^xsd:string) "uridine diphosphorhamnose-flavonol 3-O-glucoside rhamnosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.159"^^xsd:string) Annotation( "MetaCyc:2.4.1.159-RXN"^^xsd:string) "Catalysis of the reaction: flavonol 3-O-D-glucoside + UDP-L-rhamnose = flavonol 3-O-L-rhamnosylglucoside + UDP."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyridoxine 5'-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.160"^^xsd:string) "uridine diphosphoglucose-pyridoxine 5'-beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.160"^^xsd:string) Annotation( "RHEA:20180"^^xsd:string) "Catalysis of the reaction: pyridoxine + UDP-D-glucose = 5'-O-beta-D-glucosylpyridoxine + H(+) + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.160"^^xsd:string) "UDPglucose:pyridoxine 5'-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.160"^^xsd:string) "UDP-glucose:pyridoxine 5'-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.160"^^xsd:string) "UDP-glucose:pyridoxine 5'-O-beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.160"^^xsd:string) "UDP-glucose-pyridoxine glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.164"^^xsd:string) "UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,6-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.164"^^xsd:string) "uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->6-acetylglucosaminyltransferase"^^xsd:string) AnnotationAssertion(rdfs:label "galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,6-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.164"^^xsd:string) Annotation( "MetaCyc:2.4.1.164-RXN"^^xsd:string) "Catalysis of the reaction: D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyceramide + UDP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.165"^^xsd:string) Annotation( "MetaCyc:2.4.1.165-RXN"^^xsd:string) "Catalysis of the reaction: N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-beta-D-galactosaminyl-1,4-(N-acetyl-alpha-neuraminyl-2,3)-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.165"^^xsd:string) "UDP-N-acetyl-D-galactosamine:N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,4-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.165"^^xsd:string) "uridine diphosphoacetylgalactosamine-acetylneuraminyl(alpha2->3)galactosyl(beta1->4)glucosyl beta1->4-acetylgalactosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.166"^^xsd:string) "raffinose (raffinose donor) galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.166"^^xsd:string) "raffinose:raffinose alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "raffinose-raffinose alpha-galactotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.166"^^xsd:string) "raffinose:raffinose alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.166"^^xsd:string) Annotation( "MetaCyc:2.4.1.166-RXN"^^xsd:string) "Catalysis of the reaction: 2 raffinose = sucrose + 1F-alpha-D-galactosylraffinose."^^xsd:string) AnnotationAssertion( "raffinose-raffinose alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "raffinose-raffinose a-galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.167"^^xsd:string) "UDP-galactose:sucrose 6F-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.167"^^xsd:string) Annotation( "MetaCyc:2.4.1.167-RXN"^^xsd:string) "Catalysis of the reaction: sucrose + UDP-galactose = 6F-alpha-D-galactosylsucrose + UDP."^^xsd:string) AnnotationAssertion(rdfs:label "sucrose 6F-alpha-galactotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.167"^^xsd:string) "UDPgalactose:sucrose 6F-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.167"^^xsd:string) "UDPgalactose:sucrose 6fru-alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.167"^^xsd:string) "sucrose 6F-alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "sucrose 6(F)-alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.167"^^xsd:string) "uridine diphosphogalactose-sucrose 6F-alpha-galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.171"^^xsd:string) "uridine diphosphoglucose-methylazoxymethanol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.171"^^xsd:string) "UDP-glucose:methyl-ONN-azoxymethanol beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "methyl-ONN-azoxymethanol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methyl-ONN-azoxymethanol beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.171"^^xsd:string) Annotation( "MetaCyc:2.4.1.171-RXN"^^xsd:string) "Catalysis of the reaction: methylazoxymethanol + UDP-D-glucose = H+ + cycasin + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.171"^^xsd:string) "UDPglucose-methylazoxymethanol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.171"^^xsd:string) "cycasin synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "N-acetylgalactosaminyltransferase I activity"^^xsd:string) AnnotationAssertion( "glucuronylgalactosylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.174"^^xsd:string) "uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.174"^^xsd:string) "uridine diphosphoacetylgalactosamine-chondroitinacetylgalactosaminyltransferase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.174"^^xsd:string) "UDP-N-acetyl-D-galactosamine:D-glucuronyl-1,3-beta-D-galactosyl-proteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.174"^^xsd:string) Annotation( "MetaCyc:2.4.1.174-RXN"^^xsd:string) "Catalysis of the reaction: D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.175"^^xsd:string) Annotation( "MetaCyc:2.4.1.175-RXN"^^xsd:string) "Catalysis of the reaction: D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP."^^xsd:string) AnnotationAssertion( "glucuronyl-N-acetylgalactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion( "glucuronyl-N-acetylgalactosaminylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.175"^^xsd:string) "chondroitin synthase activity"^^xsd:string) AnnotationAssertion( "N-acetylgalactosaminyltransferase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.175"^^xsd:string) "UDP-N-acetyl-D-galactosamine:beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.175"^^xsd:string) "uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.175"^^xsd:string) "UDP-N-acetyl-D-galactosamine:D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.178"^^xsd:string) "cyanohydrin glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.178"^^xsd:string) "UDPglucose:4-hydroxymandelonitrile glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.178"^^xsd:string) "UDP-glucose:4-hydroxymandelonitrile glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.178"^^xsd:string) Annotation( "RHEA:15964"^^xsd:string) "Catalysis of the reaction: 4-hydroxymandelonitrile + UDP-D-glucose = H(+) + taxiphyllin + UDP."^^xsd:string) AnnotationAssertion(rdfs:label "hydroxymandelonitrile glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lactosylceramide beta-1,3-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.179"^^xsd:string) "UDPgalactose:D-galactosyl-1,4-beta-D-glucosyl-R beta-1,3-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.179"^^xsd:string) "UDP-galactose:D-galactosyl-1,4-beta-D-glucosyl-R beta-1,3-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.179"^^xsd:string) Annotation( "RHEA:18416"^^xsd:string) "Catalysis of the reaction: D-galactosyl-(1->4)-beta-D-glucosyl-R + UDP-D-galactose = D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R + H(+) + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.179"^^xsd:string) "uridine diphosphogalactose-lactosylceramide beta1->3-galactosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.180"^^xsd:string) "uridine diphosphoacetylmannosaminuronate-acetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.180"^^xsd:string) "ManNAcA transferase activity"^^xsd:string) AnnotationAssertion( "LPS N-acetylmannosaminouronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.180"^^xsd:string) Annotation( "MetaCyc:2.4.1.180-RXN"^^xsd:string) "Catalysis of the reaction: lipopolysaccharide + UDP-N-acetylmannosaminouronate = N-acetyl-beta-D-mannosaminouronosyl-1,4-lipopolysaccharide + UDP."^^xsd:string) AnnotationAssertion(rdfs:label "lipopolysaccharide N-acetylmannosaminouronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.180"^^xsd:string) "UDP-N-acetyl-beta-D-mannosaminouronate:lipopolysaccharide N-acetyl-beta-D-mannosaminouronosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroxyanthraquinone glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.181"^^xsd:string) Annotation( "MetaCyc:2.4.1.181-RXN"^^xsd:string) "Catalysis of the reaction: a hydroxyanthraquinone + UDP-D-glucose = a glucosyloxyanthraquinone + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.181"^^xsd:string) "UDP-glucose:hydroxyanthraquinone O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.181"^^xsd:string) "UDPglucose:hydroxyanthraquinone O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.181"^^xsd:string) "anthraquinone-specific glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.181"^^xsd:string) "uridine diphosphoglucose-anthraquinone glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.185"^^xsd:string) "UDPglucose:flavanone 7-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.185"^^xsd:string) "naringenin 7-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.185"^^xsd:string) Annotation( "MetaCyc:2.4.1.185-RXN"^^xsd:string) "Catalysis of the reaction: a flavanone + UDP-D-glucose = a flavanone 7-O-beta-D-glucoside + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.185"^^xsd:string) "uridine diphosphoglucose-flavanone 7-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "flavanone 7-O-beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.185"^^xsd:string) "hesperetin 7-O-glucosyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.185"^^xsd:string) "UDP-glucose:flavanone 7-O-beta-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.187"^^xsd:string) "N-acetylmannosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.187"^^xsd:string) "uridine diphosphoacetyl-mannosamineacetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.187"^^xsd:string) "UDP-N-acetylmannosamine:N-acetylglucosaminyl diphosphorylundecaprenol N-acetylmannosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.187"^^xsd:string) "UDP-N-acetyl-D-mannosamine:N-acetyl-beta-D-glucosaminyldiphosphoundecaprenol beta-1,4-N-acetylmannosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.187"^^xsd:string) Annotation( "MetaCyc:2.4.1.187-RXN"^^xsd:string) "Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-N-acetyl-D-mannosamine = N-acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.188"^^xsd:string) "UDP-glucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.188"^^xsd:string) "UDP-D-glucose:N-acetylglucosaminyl pyrophosphorylundecaprenol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.188"^^xsd:string) "uridine diphosphoglucose-acetylglucosaminylpyrophosphorylundecaprenol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.188"^^xsd:string) "UDPglucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.188"^^xsd:string) Annotation( "MetaCyc:2.4.1.188-RXN"^^xsd:string) "Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-D-glucose = beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.190"^^xsd:string) Annotation( "RHEA:14152"^^xsd:string) "Catalysis of the reaction: luteolin 7-O-beta-D-glucosiduronate + UDP-alpha-D-glucuronate = H(+) + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.190"^^xsd:string) "LMT activity"^^xsd:string) AnnotationAssertion(rdfs:label "luteolin-7-O-glucuronide 7-O-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.190"^^xsd:string) "UDP-glucuronate:luteolin 7-O-glucuronide-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.190"^^xsd:string) "luteolin-7-O-glucuronide 2''-O-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.190"^^xsd:string) "UDP-glucuronate:luteolin-7-O-beta-D-glucuronide 2''-O-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.190"^^xsd:string) "uridine diphosphoglucuronate-luteolin 7-O-glucuronide glucuronosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.191"^^xsd:string) "UDP-glucuronate:luteolin 7-O-diglucuronide-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.191"^^xsd:string) "UDPglucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.191"^^xsd:string) Annotation( "RHEA:22119"^^xsd:string) "Catalysis of the reaction: luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP-alpha-D-glucuronate = H(+) + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] 4'-O-beta-D-glucosiduronate + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.191"^^xsd:string) "uridine diphosphoglucuronate-luteolin 7-O-diglucuronide glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.191"^^xsd:string) "LDT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.191"^^xsd:string) "UDPglucuronate:luteolin 7-O-diglucuronide-4'-O-glucuronosyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.191"^^xsd:string) "UDP-glucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.192"^^xsd:string) "nuatigenin 3beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.192"^^xsd:string) "UDPglucose:(20S,22S,25S)-22,25-epoxyfurost-5-ene-3beta,26-diol 3-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nuatigenin 3-beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.192"^^xsd:string) "uridine diphosphoglucose-nuatigenin glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.192"^^xsd:string) "UDP-glucose:(20S,22S,25S)-22,25-epoxyfurost-5-ene-3beta,26-diol 3-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.192"^^xsd:string) Annotation( "RHEA:19332"^^xsd:string) "Catalysis of the reaction: nuatigenin + UDP-D-glucose = H(+) + nuatigenin 3-beta-D-glucopyranoside + UDP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.193"^^xsd:string) "sarsapogenin 3beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.193"^^xsd:string) "UDPglucose:(25S)-5beta-spirostan-3beta-ol 3-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.193"^^xsd:string) "UDP-glucose:(25S)-5beta-spirostan-3beta-ol 3-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sarsapogenin 3-beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.193"^^xsd:string) Annotation( "RHEA:14464"^^xsd:string) "Catalysis of the reaction: (25S)-5beta-spirostan-3beta-ol + UDP-D-glucose = (25S)-5beta-spirostan-3beta-yl beta-D-glucoside + H(+) + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.193"^^xsd:string) "uridine diphosphoglucose-sarsapogenin glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.194"^^xsd:string) "HBA glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.194"^^xsd:string) "uridine diphosphoglucose-4-hydroxybenzoate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.194"^^xsd:string) "UDP-glucose:4-(beta-D-glucopyranosyloxy)benzoic acid glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.194"^^xsd:string) "UDP-glucose:4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.194"^^xsd:string) "PHB glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.194"^^xsd:string) "PHB-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.194"^^xsd:string) "UDPglucose:4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.194"^^xsd:string) "p-hydroxybenzoate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.194"^^xsd:string) Annotation( "RHEA:15156"^^xsd:string) "Catalysis of the reaction: 4-hydroxybenzoate + UDP-D-glucose = 4-(beta-D-glucosyloxy)benzoate + H(+) + UDP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thiohydroximate beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.195"^^xsd:string) "UDP-glucose:thiohydroximate S-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.195"^^xsd:string) "uridine diphosphoglucose-thiohydroximate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.195"^^xsd:string) Annotation( "MetaCyc:2.4.1.195-RXN"^^xsd:string) "Catalysis of the reaction: phenylthioacetohydroximate + UDP-D-glucose = desulfoglucotropeolin + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.195"^^xsd:string) "thiohydroximate S-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.195"^^xsd:string) "UDPG:thiohydroximate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.195"^^xsd:string) "UDP-glucose:N-hydroxy-2-phenylethanethioamide S-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.195"^^xsd:string) "desulfoglucosinolate-uridine diphosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.195"^^xsd:string) "N-hydroxythioamide S-beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.195"^^xsd:string) "thiohydroximate glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.199"^^xsd:string) Annotation( "MetaCyc:2.4.1.199-RXN"^^xsd:string) "Catalysis of the reaction: (1->6)-alpha-D-mannosyloligosaccharide + beta-D-mannosylphosphodecaprenol = (1->6)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-oligosaccharide + decaprenol phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.199"^^xsd:string) "mannosylphospholipid-methylmannoside alpha-1,6-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.199"^^xsd:string) "beta-D-mannosylphosphodecaprenol:1,6-alpha-D-mannosyloligosaccharide 1,6-alpha-D-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-mannosylphosphodecaprenol-mannooligosaccharide 6-mannosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-1,6-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.201"^^xsd:string) "mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.201"^^xsd:string) "N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase VI activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.201"^^xsd:string) "N-acetylglucosaminyltransferase VI activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.201"^^xsd:string) "uridine diphosphoacetylglucosamine-glycopeptide beta-1->4-acetylglucosaminyltransferase VI activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.201"^^xsd:string) "UDP-N-acetyl-D-glucosamine:2,6-bis(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.201"^^xsd:string) "uridine diphosphoacetylglucosamine-glycopeptide beta-1->4-acetylglucosaminyltransferase VI"^^xsd:string) AnnotationAssertion( "alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.201"^^xsd:string) Annotation( "MetaCyc:2.4.1.201-RXN"^^xsd:string) "Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-B-glucosaminyl-1,2)-beta-D-mannosyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-D-glucosaminyl-1,2-beta)-(N-acetyl-D-glucosaminyl-1,4-beta)-D-mannosyl-R + UDP."^^xsd:string) AnnotationAssertion( "mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyl-transferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.202"^^xsd:string) "uridine diphosphoglucose-2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.202"^^xsd:string) "UDP-glucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.202"^^xsd:string) "UDPglucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.202"^^xsd:string) Annotation( "MetaCyc:2.4.1.202-RXN"^^xsd:string) "Catalysis of the reaction: 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one + UDP-D-glucose = 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucoside + UDP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.205"^^xsd:string) "1,6-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.205"^^xsd:string) "uridine diphosphogalactose-galactogen galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.205"^^xsd:string) "UDPgalactose:galactogen beta-1,6-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.205"^^xsd:string) "beta-(1,6)-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactogen 6-beta-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.205"^^xsd:string) "galactogen 6beta-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.205"^^xsd:string) Annotation( "MetaCyc:2.4.1.205-RXN"^^xsd:string) "Catalysis of the reaction: galactogen + UDP-galactose = 1,6-beta-D-galctosylgalactogen + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.205"^^xsd:string) "UDP-galactose:galactogen beta-1,6-D-galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.206"^^xsd:string) "beta1->3-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.206"^^xsd:string) "UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.206"^^xsd:string) "uridine diphosphoacetylglucosamine-lactosylceramide beta-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.206"^^xsd:string) "lactosylceramide beta-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.206"^^xsd:string) "LA2 synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.206"^^xsd:string) Annotation( "MetaCyc:2.4.1.206-RXN"^^xsd:string) "Catalysis of the reaction: cytolipin-H + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP."^^xsd:string) AnnotationAssertion(rdfs:label "lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.208"^^xsd:string) "UDP-glucose:1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol (1->2) glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.208"^^xsd:string) "monoglucosyl diacylglycerol (1->2) glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.208"^^xsd:string) "DGlcDAG synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.208"^^xsd:string) "MGlcDAG (1->2) glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "diglucosyl diacylglycerol (DGlcDAG) synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.208"^^xsd:string) Annotation( "MetaCyc:2.4.1.208-RXN"^^xsd:string) "Catalysis of the reaction: 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-D-glucose = UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1,2)-O-alpha-D-glucopyranosyl)-sn-glycerol."^^xsd:string) AnnotationAssertion(rdfs:label "diglucosyl diacylglycerol synthase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.23"^^xsd:string) "UDPgalactose:sphingosine 1-beta-galactotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sphingosine beta-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.23"^^xsd:string) "psychosine-UDP galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.23"^^xsd:string) "galactosyl-sphingosine transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.23"^^xsd:string) "uridine diphosphogalactose-sphingosine beta-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.23"^^xsd:string) "UDPgalactose:sphingosine O-galactosyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.23"^^xsd:string) Annotation( "RHEA:19488"^^xsd:string) "Catalysis of the reaction: sphingosine + UDP-D-galactose = H(+) + psychosine + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.23"^^xsd:string) "psychosine-uridine diphosphate galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.23"^^xsd:string) "UDP-galactose:sphingosine 1-beta-galactotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.32"^^xsd:string) "GDP-man-beta-mannan mannosyltransferase activity"^^xsd:string) AnnotationAssertion( "glucomannan 4-b-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.32"^^xsd:string) Annotation( "MetaCyc:2.4.1.32-RXN"^^xsd:string) "Catalysis of the reaction: glucomannan(n) + GDP-mannose = glucomannan(n+1) + GDP."^^xsd:string) AnnotationAssertion( "GDP-mannose:glucomannan 1,4-beta-D-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucomannan 4-beta-mannosyltransferase activity"^^xsd:string) AnnotationAssertion( "glucomannan-synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.36"^^xsd:string) "GDP-glucose-glucosephosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.36"^^xsd:string) "GDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.36"^^xsd:string) "trehalose phosphate synthase (GDP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.36"^^xsd:string) "GDPglucose-glucose-phosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.36"^^xsd:string) "GDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.36"^^xsd:string) Annotation( "MetaCyc:2.4.1.36-RXN"^^xsd:string) "Catalysis of the reaction: GDP-D-glucose + glucose-6-phosphate = alpha,alpha-trehalose 6-phosphate + GDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.36"^^xsd:string) "guanosine diphosphoglucose-glucose phosphate glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.39"^^xsd:string) Annotation( "RHEA:14156"^^xsd:string) "Catalysis of the reaction: estradiol-17alpha 3-D-glucuronoside + UDP-N-acetyl-alpha-D-glucosamine = 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside + H(+) + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.39"^^xsd:string) "UDP-N-acetyl-D-glucosamine:estradiol-17alpha-3-D-glucuronoside 17alpha-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.39"^^xsd:string) "uridine diphosphoacetylglucosamine-steroid acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.39"^^xsd:string) "hydroxy steroid acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.39"^^xsd:string) "steroid acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "steroid N-acetylglucosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.43"^^xsd:string) Annotation( "MetaCyc:2.4.1.43-RXN"^^xsd:string) "Catalysis of the reaction: UDP-D-galacturonate + 1,4-alpha-D-galacturonosyl(n) = 1,4-alpha-D-galacturonosyl(n+1) + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.43"^^xsd:string) "UDP-D-galacturonate:1,4-alpha-poly-D-galacturonate 4-alpha-D-galacturonosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "polygalacturonate 4-alpha-galacturonosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.43"^^xsd:string) "UDP galacturonate-polygalacturonate alpha-galacturonosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.43"^^xsd:string) "uridine diphosphogalacturonate-polygalacturonate alpha-galacturonosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.47"^^xsd:string) "UDPgalactose:N-acylsphingosine D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.47"^^xsd:string) Annotation( "MetaCyc:2.4.1.47-RXN"^^xsd:string) "Catalysis of the reaction: ceramide + UDP-galactose = D-galactosylceramide + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.47"^^xsd:string) "UDP-galactose:N-acylsphingosine D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acylsphingosine galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.47"^^xsd:string) "uridine diphosphogalactose-acylsphingosine galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.47"^^xsd:string) "UDP galactose-N-acylsphingosine galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.48"^^xsd:string) "GDP-mannose:heteroglycan 2-(or 3-)-alpha-D-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.48"^^xsd:string) "guanosine diphosphomannose-heteroglycan alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.48"^^xsd:string) "GDP mannose alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "heteroglycan alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.48"^^xsd:string) "Catalysis of the reaction: heteroglycan + GDP-mannose = alpha-D-mannosylheteroglycan + GDP."^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "heteropolysaccharide alpha-mannosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.52"^^xsd:string) "uridine diphosphoglucose-poly(glycerol-phosphate) alpha-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "poly(glycerol-phosphate) alpha-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.52"^^xsd:string) Annotation( "MetaCyc:2.4.1.52-RXN"^^xsd:string) "Catalysis of the reaction: poly(glycerol phosphate) + UDP-D-glucose = alpha-D-glucosylpoly(glycerol phosphate) + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.52"^^xsd:string) "UDP-glucose:poly(glycerol-phosphate) alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.52"^^xsd:string) "UDP glucose-poly(glycerol-phosphate) alpha-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.52"^^xsd:string) "UDPglucose:poly(glycerol-phosphate) alpha-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.53"^^xsd:string) "UDP glucose-poly(ribitol-phosphate) beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.53"^^xsd:string) "uridine diphosphoglucose-poly(ribitol-phosphate) beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.53"^^xsd:string) Annotation( "MetaCyc:2.4.1.53-RXN"^^xsd:string) "Catalysis of the reaction: poly(ribitol phosphate) + UDP-D-glucose = beta-D-glucosylpoly(ribitol phosphate) + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.53"^^xsd:string) "UDP-glucose:poly(ribitol-phosphate) beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.53"^^xsd:string) "UDP-D-glucose:polyribitol phosphate glucosyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.53"^^xsd:string) "UDP-D-glucose polyribitol phosphate glucosyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.53"^^xsd:string) "UDPglucose:poly(ribitol-phosphate) beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "poly(ribitol-phosphate) beta-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.54"^^xsd:string) "guanosine diphosphomannose-undecaprenyl phosphate mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.54"^^xsd:string) "GDP mannose-undecaprenyl phosphate mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.54"^^xsd:string) "Catalysis of the reaction: GDP-mannose + undecaprenyl phosphate = GDP + D-mannosyl-1-phosphoundecaprenol."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.54"^^xsd:string) "GDP-D-mannose:lipid phosphate transmannosylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "undecaprenyl-phosphate mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.54"^^xsd:string) "GDP-mannose:undecaprenyl-phosphate D-mannosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "galactinol-raffinose galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.67"^^xsd:string) "stachyose synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.67"^^xsd:string) "alpha-D-(1->3)-galactosyl-myo-inositol:raffinose galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.67"^^xsd:string) Annotation( "MetaCyc:2.4.1.67-RXN"^^xsd:string) "Catalysis of the reaction: raffinose + 1-alpha-D-galactosyl-myo-inositol = stachyose + myo-inositol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.70"^^xsd:string) "UDP acetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.70"^^xsd:string) "uridine diphosphoacetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.70"^^xsd:string) "UDP-N-acetyl-D-glucosamine:poly(ribitol-phosphate) N-acetyl-D-glucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.70"^^xsd:string) Annotation( "MetaCyc:2.4.1.70-RXN"^^xsd:string) "Catalysis of the reaction: poly(ribitol phosphate) + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-poly(ribitol phosphate) + UDP."^^xsd:string) AnnotationAssertion(rdfs:label "poly(ribitol-phosphate) N-acetylglucosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "LPS glucosyltransferase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.73"^^xsd:string) Annotation( "MetaCyc:2.4.1.73-RXN"^^xsd:string) "Catalysis of the reaction: lipopolysaccharide + UDP-D-glucose = D-glucosyl-lipopolysaccharide + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.73"^^xsd:string) "UDPglucose:galactosyl-lipopolysaccharide alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lipopolysaccharide glucosyltransferase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.73"^^xsd:string) "UDP-glucose:galactosyl-lipopolysaccharide alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.73"^^xsd:string) "uridine diphosphoglucose-galactosylpolysaccharide glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.74"^^xsd:string) "UDPgalactose:glycosaminoglycan D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.74"^^xsd:string) "uridine diphosphogalactose-mucopolysaccharide galactosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycosaminoglycan galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.74"^^xsd:string) Annotation( "MetaCyc:2.4.1.74-RXN"^^xsd:string) "Catalysis of the reaction: glycosaminoglycan + UDP-galactose = D-galactosylglycosaminoglycan + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.74"^^xsd:string) "UDP-galactose:glycosaminoglycan D-galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.78"^^xsd:string) "UDPglucose:polyprenol monophosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.78"^^xsd:string) Annotation( "MetaCyc:2.4.1.78-RXN"^^xsd:string) "Catalysis of the reaction: polyprenyl phosphate + UDP-D-glucose = polyprenylphosphate-glucose + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.78"^^xsd:string) "uridine diphosphoglucose-polyprenol monophosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphopolyprenol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.78"^^xsd:string) "UDP-glucose:phosphopolyprenol D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.78"^^xsd:string) "UDPglucose:phosphopolyprenol D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.79"^^xsd:string) "uridine diphosphoacetylgalactosamine-galactosylgalactosylglucosylceramide acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.79"^^xsd:string) "globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.79"^^xsd:string) "UDP-N-acetylgalactosamine:globotriaosylceramide beta1,3-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.79"^^xsd:string) "globoside synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.79"^^xsd:string) "UDP-N-acetylgalactosamine:globotriaosylceramide beta-3-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.79"^^xsd:string) "galactosylgalactosylglucosylceramide beta-D- activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.79"^^xsd:string) Annotation( "MetaCyc:2.4.1.79-RXN"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide = UDP + beta-N-acetyl-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.79"^^xsd:string) "UDP-N-acetyl-D-galactosamine:alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide 3III-beta-N-acetyl-D-galactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.79"^^xsd:string) "UDP-N-acetyl-D-galactosamine:D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide beta-N-acetyl-D-galactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.79"^^xsd:string) "beta3GalNAc-T1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.79"^^xsd:string) "globoside synthase activity"^^xsd:string) AnnotationAssertion( "globotriosylceramide beta-1,6-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.79"^^xsd:string) "beta-3GalNAc-T1 activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.82"^^xsd:string) Annotation( "MetaCyc:2.4.1.82-RXN"^^xsd:string) "Catalysis of the reaction: sucrose + 1-alpha-D-galactosyl-myo-inositol = raffinose + myo-inositol."^^xsd:string) AnnotationAssertion( "galactosyltransferase, galactinol-sucrose"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.82"^^xsd:string) "1-alpha-D-galactosyl-myo-inositol:sucrose 6-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.82"^^xsd:string) "alpha-D-galactosyl-(1->3)-myo-inositol:sucrose 6-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactinol-sucrose galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "galactinol:sucrose 6-galactosyl transferase activity"^^xsd:string) AnnotationAssertion( "raffinose synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.86"^^xsd:string) "UDPgalactose:N-acetyl-D-glucosaminyl-1,3-D-galactosyl-1,4-D-glucosylceramide beta-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.86"^^xsd:string) Annotation( "MetaCyc:2.4.1.86-RXN"^^xsd:string) "Catalysis of the reaction: N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = D-galactosyl-N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.86"^^xsd:string) "paragloboside synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.86"^^xsd:string) "UDP-galactose:N-acetyl-D-glucosaminyl-1,3-D-galactosyl-1,4-D-glucosylceramide beta-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.86"^^xsd:string) "uridine diphosphogalactose-acetyl-glucosaminylgalactosylglucosylceramide galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.86"^^xsd:string) "GalT-4"^^xsd:string) AnnotationAssertion(rdfs:label "glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) "beta-D-galactosyl-N-acetylglucosaminylglycopeptide alpha-1,3-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) "UDP-galactose:N-acetyllactosaminide 3-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) "uridine diphosphogalactose-galactosylacetylglucosaminylgalactosylglucosylceramide galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) "uridine diphosphogalactose-acetyllactosamine alpha1->3-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) "uridine diphosphogalactose-galactosylacetylglucosaminylgalactosyl-glucosylceramide galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "N-acetyllactosaminide alpha-1,3-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) "uridine diphosphogalactose-acetyllactosamine alpha-1->3-galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "beta-galactosyl-N-acetylglucosaminylglycopeptide alpha-1,3-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) "glucosaminylglycopeptide alpha-1,3-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) "UDP-Gal:Gal-beta-1->4GlcNAc-R alpha-1->3-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) "UDPgalactose:beta-D-galactosyl-beta-1,4-N-acetyl-D-glucosaminyl-glycopeptide alpha-1,3-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) "alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) Annotation( "MetaCyc:2.4.1.87-RXN"^^xsd:string) "Catalysis of the reaction: beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP-galactose = alpha-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) "UDP-Gal:N-acetyllactosaminide alpha-1,3-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) "uridine diphosphogalactose-acetyllactosamine galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) "UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha-(1,3)-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) "UDP-Gal:N-acetyllactosaminide alpha-(1,3)-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) "UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha(1,3)-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetyllactosaminide 3-alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) "UDP-Gal:Galbeta1->4GlcNAc-R alpha1->3-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) "UDP-Gal:N-acetyllactosaminide alpha(1,3)-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.87"^^xsd:string) "UDP-galactose-acetyllactosamine alpha-D-galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.88"^^xsd:string) "globoside acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "globoside alpha-N-acetylgalactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.88"^^xsd:string) "forssman synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.88"^^xsd:string) Annotation( "MetaCyc:2.4.1.88-RXN"^^xsd:string) "Catalysis of the reaction: N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.88"^^xsd:string) "UDP-N-acetyl-D-galactosamine:N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide alpha-N-acetyl-D-galactosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.88"^^xsd:string) "Forssman synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.88"^^xsd:string) "uridine diphosphoacetylgalactosamine-globoside alpha-acetylgalactosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "bilirubin-glucuronoside glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.95"^^xsd:string) "bilirubin-glucuronoside:bilirubin-glucuronoside D-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.95"^^xsd:string) "bilirubin glucuronoside glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.95"^^xsd:string) "bilirubin monoglucuronide transglucuronidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.95"^^xsd:string) Annotation( "RHEA:16888"^^xsd:string) "Catalysis of the reaction: 2 bilirubin-glucuronoside = bilirubin + bilirubin-bisglucuronoside."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.96"^^xsd:string) "UDPgalactose:sn-glycerol-3-phosphate 1-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.96"^^xsd:string) "UDP-galactose:sn-glycerol-3-phosphate 1-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.96"^^xsd:string) "UDPgalactose:sn-glycerol-3-phosphate alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.96"^^xsd:string) "UDP-Gal:sn-glycero-3-phosphoric acid 1-alpha-galactosyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.96"^^xsd:string) Annotation( "RHEA:20344"^^xsd:string) "Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 1-O-alpha-D-galactosyl-sn-glycerol 3-phosphate + H(+) + UDP."^^xsd:string) AnnotationAssertion(rdfs:label "sn-glycerol-3-phosphate 1-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.96"^^xsd:string) "uridine diphosphogalactose-glycerol phosphate galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.96"^^xsd:string) "glycerol 3-phosphate 1alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.96"^^xsd:string) "isofloridoside-phosphate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.12"^^xsd:string) "NMN synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.12"^^xsd:string) Annotation( "RHEA:16152"^^xsd:string) "Catalysis of the reaction: diphosphate + nicotinamide mononucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinamide."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.12"^^xsd:string) "nicotinamide mononucleotide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.12"^^xsd:string) "NMN diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.12"^^xsd:string) "NMN pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nicotinamide phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.12"^^xsd:string) "nicotinamide mononucleotide pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.12"^^xsd:string) "nicotinamide-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.20"^^xsd:string) "dioxotetrahydropyrimidine ribonucleotide pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dioxotetrahydropyrimidine phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.20"^^xsd:string) "dioxotetrahydropyrimidine-ribonucleotide diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.20"^^xsd:string) Annotation( "MetaCyc:2.4.2.20-RXN"^^xsd:string) "Catalysis of the reaction: pyrophosphate + a 2,4-dioxotetrahydropyrimidine D-ribonucleotide = PRPP + a 2,4-dioxotetrahydropyrimidine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.20"^^xsd:string) "dioxotetrahydropyrimidine phosphoribosyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.20"^^xsd:string) "2,4-dioxotetrahydropyrimidine-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.20"^^xsd:string) "dioxotetrahydropyrimidine-ribonucleotide pyrophosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.27"^^xsd:string) "dTDP-L-dihydrostreptose:streptidine-6-phosphate dihydrostreptosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.27"^^xsd:string) Annotation( "RHEA:24395"^^xsd:string) "Catalysis of the reaction: dTDP-L-dihydrostreptose + streptidine 6-phosphate = O-(1->4)-alpha-L-dihydrostreptosyl-streptidine 6-phosphate + dTDP + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.27"^^xsd:string) "thymidine diphosphodihydrostreptose-streptidine 6-phosphate dihydrostreptosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.27"^^xsd:string) "dTDPdihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dTDP-dihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.32"^^xsd:string) Annotation( "MetaCyc:2.4.2.32-RXN"^^xsd:string) "Catalysis of the reaction: dolichol-phosphate + UDP-D-xylose = dolichyl D-xylosyl phosphate + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.32"^^xsd:string) "UDP-D-xylose:dolichyl-phosphate D-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dolichyl-phosphate D-xylosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.33"^^xsd:string) Annotation( "MetaCyc:2.4.2.33-RXN"^^xsd:string) "Catalysis of the reaction: dolichyl D-xylosyl phosphate + protein = dolichol-phosphate + D-xylosylprotein."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.33"^^xsd:string) "dolichyl-D-xylosyl-phosphate:protein D-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dolichyl-xylosyl-phosphate-protein xylosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "flavonol-3-O-glycoside xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.35"^^xsd:string) "UDP-D-xylose:flavonol-3-O-glycoside 2''-O-beta-D-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.35"^^xsd:string) Annotation( "MetaCyc:2.4.2.35-RXN"^^xsd:string) "Catalysis of the reaction: flavonol 3-O-glycoside + UDP-D-xylose = flavonol 3-O-D-xylosylglycoside + UDP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "NAD-diphthamide ADP-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.36"^^xsd:string) "mono(ADP-ribosyl)transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.36"^^xsd:string) "ADP-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.36"^^xsd:string) "Catalysis of the reaction: peptide diphthamide + NAD+ = peptide N-(ADP-D-ribosyl)diphthamide + niacinamide."^^xsd:string) AnnotationAssertion(rdfs:label "NAD+-diphthamide ADP-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.36"^^xsd:string) "NAD+:peptide-diphthamide N-(ADP-D-ribosyl)transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.99.11"^^xsd:string) "cytidine monophosphoacetylneuraminate-lactosylceramide sialyltransferase"^^xsd:string) AnnotationAssertion(rdfs:label "lactosylceramide alpha-2,6-N-sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.11"^^xsd:string) "CMP-N-acetylneuraminic acid:lactosylceramide sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.11"^^xsd:string) "CMP-sialic acid:lactosylceramide sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.11"^^xsd:string) Annotation( "MetaCyc:2.4.99.11-RXN"^^xsd:string) "Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,6-beta-galactosyl-1,4-beta-D-glucosylceramide + CMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.11"^^xsd:string) "CMP-acetylneuraminate-lactosylceramide-sialyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.11"^^xsd:string) "CMP-N-acetylneuraminate:lactosylceramide alpha-2,6-N-acetylneuraminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.99.2"^^xsd:string) Annotation( "MetaCyc:2.4.99.2-RXN"^^xsd:string) "Catalysis of the reaction: D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + CMP-N-acetylneuraminate = N-acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + CMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.2"^^xsd:string) "CMP-N-acetylneuraminate:D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetylneuraminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "monosialoganglioside sialyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.99.5"^^xsd:string) "CMP-N-acetylneuraminate:1,2-diacyl-3-beta-D-galactosyl-sn-glycerol N-acetylneuraminyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactosyldiacylglycerol alpha-2,3-sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.5"^^xsd:string) Annotation( "RHEA:11667"^^xsd:string) "Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + CMP-N-acetyl-beta-neuraminate = 1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol + CMP + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.99.7"^^xsd:string) "sialyltransferase 7D activity"^^xsd:string) AnnotationAssertion(rdfs:label "(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.7"^^xsd:string) "(alpha-N-acetylneuraminyl-2,3-alpha-galactosyl-1,3)-N-acetyl-galactosaminide alpha-2,6-sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.7"^^xsd:string) Annotation( "RHEA:10479"^^xsd:string) "Catalysis of the reaction: alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R + CMP-N-acetyl-beta-neuraminate = alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-D-galactosaminyl-R + CMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.7"^^xsd:string) "CMP-N-acetylneuraminate:(alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3)-N-acetyl-D-galactosaminide alpha-2,6-N-acetylneuraminyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.7"^^xsd:string) "alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase activity"^^xsd:string) AnnotationAssertion( "(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.7"^^xsd:string) "NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.7"^^xsd:string) "cytidine monophosphoacetylneuraminate-(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide-alpha-2,6-sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.7"^^xsd:string) "sialyltransferase 3C activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.7"^^xsd:string) "ST6GALNAC activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.7"^^xsd:string) "SIAT7"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.99.9"^^xsd:string) "CMP-acetylneuraminate-lactosylceramide-sialyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.9"^^xsd:string) "ganglioside GM3 synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.9"^^xsd:string) "ganglioside GM3 synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.9"^^xsd:string) "GM3 synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lactosylceramide alpha-2,3-sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.9"^^xsd:string) "CMP-N-acetylneuraminate:lactosylceramide alpha-2,3-N-acetylneuraminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.9"^^xsd:string) "CMP-acetylneuraminic acid:lactosylceramide sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.9"^^xsd:string) "CMP-sialic acid:lactosylceramide-sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.9"^^xsd:string) "GM3 synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.9"^^xsd:string) "cytidine monophosphoacetylneuraminate-lactosylceramide alpha2,3- sialyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.9"^^xsd:string) "SAT 1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.9"^^xsd:string) "cytidine monophosphoacetylneuraminate-lactosylceramide sialyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.99.9"^^xsd:string) Annotation( "MetaCyc:2.4.99.9-RXN"^^xsd:string) "Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + CMP. Alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide is also known as GM3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.36"^^xsd:string) Annotation( "MetaCyc:2.5.1.36-RXN"^^xsd:string) "Catalysis of the reaction: (6AS,11AS)-3,6A,9-trihydroxypterocarpan + dimethylallyl-pyrophosphate = glyceollin + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.36"^^xsd:string) "dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan dimethyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trihydroxypterocarpan dimethylallyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.36"^^xsd:string) "dimethylallylpyrophosphate:3,6a,9-trihydroxypterocarpan dimethylallyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.36"^^xsd:string) "dimethylallylpyrophosphate:trihydroxypterocarpan dimethylallyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.36"^^xsd:string) "dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan dimethylallyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.39"^^xsd:string) Annotation( "MetaCyc:2.5.1.39-RXN"^^xsd:string) "Catalysis of the reaction: p-hydroxybenzoate + solanesyl pyrophosphate = nonaprenyl-4-hydroxybenzoate + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxybenzoate nonaprenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.39"^^xsd:string) "p-hydroxybenzoic acid-polyprenyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.39"^^xsd:string) "p-hydroxybenzoic-polyprenyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.39"^^xsd:string) "4-hydroxybenzoate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.39"^^xsd:string) "p-hydroxybenzoate dimethylallyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.39"^^xsd:string) "solanesyl-diphosphate:4-hydroxybenzoate nonaprenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.39"^^xsd:string) "nonaprenyl-4-hydroxybenzoate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.39"^^xsd:string) "p-hydroxybenzoate polyprenyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphoglycerol geranylgeranyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.41"^^xsd:string) "geranylgeranyl-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.41"^^xsd:string) "glycerol phosphate geranylgeranyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.41"^^xsd:string) Annotation( "RHEA:23407"^^xsd:string) "Catalysis of the reaction: sn-glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = sn-3-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.41"^^xsd:string) "geranylgeranyl diphosphate:sn-glyceryl phosphate geranylgeranyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.42"^^xsd:string) "geranylgeranyloxyglycerol phosphate geranylgeranyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.42"^^xsd:string) Annotation( "RHEA:18112"^^xsd:string) "Catalysis of the reaction: sn-3-O-(geranylgeranyl)glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = 2,3-di-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.42"^^xsd:string) "geranylgeranyltransferase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.42"^^xsd:string) "geranylgeranyl diphosphate:sn-3-O-(geranylgeranyl)glycerol 1-phosphate geranylgeranyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "geranylgeranylglycerol-phosphate geranylgeranyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.44"^^xsd:string) "putrescine:putrescine 4-aminobutyltransferase (ammonia-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "homospermidine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.44"^^xsd:string) Annotation( "MetaCyc:2.5.1.44-RXN"^^xsd:string) "Catalysis of the reaction: 2 putrescine = NH3 + sym-homospermidine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "asparagine-oxo-acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.14"^^xsd:string) "L-asparagine:2-oxo-acid aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "asparagine-oxo-acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.14"^^xsd:string) Annotation( "MetaCyc:2.6.1.14-RXN"^^xsd:string) "Catalysis of the reaction: a 2-oxo acid + L-asparagine = an amino acid + 2-oxosuccinamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.14"^^xsd:string) "asparagine--oxo-acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.14"^^xsd:string) "asparagine-keto acid aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.22"^^xsd:string) "L-3-aminoisobutyrate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(S)-3-amino-2-methylpropionate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.22"^^xsd:string) "beta-aminoisobutyrate-alpha-ketoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.22"^^xsd:string) "beta-aminobutyric transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.22"^^xsd:string) "L-AIBAT activity"^^xsd:string) AnnotationAssertion( "(S)-3-amino-2-methylpropionate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.22"^^xsd:string) "L-3-aminoisobutyric aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.22"^^xsd:string) "L-3-aminoisobutyrate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.22"^^xsd:string) Annotation( "RHEA:13996"^^xsd:string) "Catalysis of the reaction: (S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.22"^^xsd:string) "(S)-3-amino-2-methylpropanoate:2-oxoglutarate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.28"^^xsd:string) Annotation( "RHEA:13744"^^xsd:string) "Catalysis of the reaction: keto-phenylpyruvate + L-tryptophan = 3-(indol-3-yl)pyruvate + L-phenylalanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.28"^^xsd:string) "L-tryptophan-alpha-ketoisocaproate aminotransferase activity"^^xsd:string) AnnotationAssertion( "tryptophan-phenylpyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tryptophan-phenylpyruvate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.28"^^xsd:string) "tryptophan--phenylpyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.28"^^xsd:string) "L-tryptophan:phenylpyruvate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyridoxamine-pyruvate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.30"^^xsd:string) "pyridoxamine-pyruvic transaminase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.30"^^xsd:string) "pyridoxamine--pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion( "pyridoxamine-pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.30"^^xsd:string) Annotation( "RHEA:12844"^^xsd:string) "Catalysis of the reaction: pyridoxamine + pyruvate = L-alanine + pyridoxal."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.30"^^xsd:string) "pyridoxamine:pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.30"^^xsd:string) "pyridoxamineu-pyruvic transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.32"^^xsd:string) Annotation( "RHEA:11471"^^xsd:string) "Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + L-valine = 3-methyl-2-oxobutanoate + L-isoleucine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.32"^^xsd:string) "valine--isoleucine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.32"^^xsd:string) "valine--isoleucine transaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "valine-3-methyl-2-oxovalerate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.32"^^xsd:string) "L-valine:(S)-3-methyl-2-oxopentanoate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.32"^^xsd:string) "valine-2-keto-methylvalerate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.32"^^xsd:string) "valine--3-methyl-2-oxovalerate aminotransferase activity"^^xsd:string) AnnotationAssertion( "valine-3-methyl-2-oxovalerate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase activity"^^xsd:string) AnnotationAssertion( "UDP-4-amino-2-acetamido-2,4,6-trideoxyglucose aminotransferase activity"^^xsd:string) AnnotationAssertion( "UDP-4-amino-2-acetamido-2,4,6-trideoxyglucose transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.34"^^xsd:string) "UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.34"^^xsd:string) "uridine diphospho-4-amino-2-acetamido-2,4,6-trideoxyglucose aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.34"^^xsd:string) Annotation( "RHEA:18716"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + UDP-2-acetamido-4-amino-2,4,6-trideoxy-D-glucose = L-glutamate + UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycine-oxaloacetate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.35"^^xsd:string) "glycine--oxaloacetate aminotransferase activity"^^xsd:string) AnnotationAssertion( "glycine-oxaloacetate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.35"^^xsd:string) "glycine:oxaloacetate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.35"^^xsd:string) "glycine-oxalacetate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.35"^^xsd:string) Annotation( "RHEA:17144"^^xsd:string) "Catalysis of the reaction: glycine + oxaloacetate = L-aspartate + glyoxylate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.37"^^xsd:string) "(2-aminoethyl)phosphonate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.37"^^xsd:string) "2-aminoethylphosphonate--pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.37"^^xsd:string) "2-aminoethylphosphonate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.37"^^xsd:string) "(2-aminoethyl)phosphonic acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.37"^^xsd:string) Annotation( "RHEA:17024"^^xsd:string) "Catalysis of the reaction: (2-aminoethyl)phosphonate + pyruvate = L-alanine + phosphonoacetaldehyde."^^xsd:string) AnnotationAssertion( "2-aminoethylphosphonate-pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-aminoethylphosphonate-pyruvate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.37"^^xsd:string) "(2-aminoethyl)phosphonate--pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.37"^^xsd:string) "(2-aminoethyl)phosphonate:pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.37"^^xsd:string) "(2-aminoethyl)phosphonate transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.40"^^xsd:string) "D-beta-aminoisobutyrate:pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.40"^^xsd:string) "D-3-aminoisobutyrate--pyruvate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.40"^^xsd:string) Annotation( "RHEA:18396"^^xsd:string) "Catalysis of the reaction: (2R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.40"^^xsd:string) "D-3-aminoisobutyrate-pyruvate transaminase activity"^^xsd:string) AnnotationAssertion( "(R)-3-amino-2-methylpropanoate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.40"^^xsd:string) "D-AIBAT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.40"^^xsd:string) "D-3-aminoisobutyrate--pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.40"^^xsd:string) "(R)-3-amino-2-methylpropanoate:pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion( "(R)-3-amino-2-methylpropanoate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(R)-3-amino-2-methylpropionate-pyruvate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.40"^^xsd:string) "(R)-3-amino-2-methylpropionate--pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.40"^^xsd:string) "beta-aminoisobutyrate-pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion( "(R)-3-amino-2-methylpropionate transaminase activity"^^xsd:string) AnnotationAssertion( "(R)-3-amino-2-methylpropionate-pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.40"^^xsd:string) "beta-aminoisobutyrate--pyruvate transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.41"^^xsd:string) Annotation( "RHEA:23839"^^xsd:string) "Catalysis of the reaction: D-methionine + pyruvate = 4-methylthio-2-oxobutanoate + L-alanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.41"^^xsd:string) "D-methionine:pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion( "D-methionine-pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.41"^^xsd:string) "D-methionine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.41"^^xsd:string) "D-methionine transaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-methionine-pyruvate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.41"^^xsd:string) "D-methionine--pyruvate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.46"^^xsd:string) "L-2,4-diaminobutanoate:pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion( "diaminobutyrate-pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.46"^^xsd:string) "L-diaminobutyric acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.46"^^xsd:string) "diaminobutyrate--pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.46"^^xsd:string) Annotation( "RHEA:12383"^^xsd:string) "Catalysis of the reaction: L-2,4-diaminobutyrate + pyruvate = L-alanine + L-aspartate 4-semialdehyde."^^xsd:string) AnnotationAssertion(rdfs:label "diaminobutyrate-pyruvate transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "alanine-oxomalonate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.47"^^xsd:string) "L-alanine:oxomalonate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.47"^^xsd:string) "L-alanine-ketomalonate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.47"^^xsd:string) Annotation( "RHEA:18812"^^xsd:string) "Catalysis of the reaction: L-alanine + oxomalonate = aminomalonate + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.47"^^xsd:string) "alanine-ketomalonate (mesoxalate) transaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alanine-oxomalonate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.47"^^xsd:string) "alanine--oxomalonate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.49"^^xsd:string) Annotation( "RHEA:15276"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + L-dopa = 3,4-dihydroxyphenylpyruvate + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.49"^^xsd:string) "aspartate-DOPP transaminase (ADT)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.49"^^xsd:string) "L-dopa transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.49"^^xsd:string) "DOPA aminotransferase activity"^^xsd:string) AnnotationAssertion( "dihydroxyphenylalanine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.49"^^xsd:string) "dopa transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.49"^^xsd:string) "phenylalanine-DOPP transaminase (PDT)"^^xsd:string) AnnotationAssertion(rdfs:label "dihydroxyphenylalanine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.49"^^xsd:string) "3,4-dihydroxy-L-phenylalanine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.49"^^xsd:string) "glutamate-DOPP transaminase (GDT)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.50"^^xsd:string) Annotation( "RHEA:22923"^^xsd:string) "Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone + L-glutamine = 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.50"^^xsd:string) "L-glutamine-scyllo-inosose transaminase activity"^^xsd:string) AnnotationAssertion( "glutamine-scyllo-inosose transaminase activity"^^xsd:string) AnnotationAssertion( "glutamine-scyllo-inosose aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.50"^^xsd:string) "glutamine--scyllo-inosose transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.50"^^xsd:string) "L-glutamine-keto-scyllo-inositol aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.50"^^xsd:string) "L-glutamine:2,4,6/3,5-pentahydroxycyclohexanone aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamine-scyllo-inositol transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.50"^^xsd:string) "glutamine scyllo-inosose aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.50"^^xsd:string) "glutamine--scyllo-inosose aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.56"^^xsd:string) "L-alanine-N-amidino-3-(or 5-)keto-scyllo-inosamine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.56"^^xsd:string) Annotation( "RHEA:15500"^^xsd:string) "Catalysis of the reaction: 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate = 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.56"^^xsd:string) "1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol:pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion( "1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.56"^^xsd:string) "guanidinoaminodideoxy-scyllo-inositol-pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-phenylalanine:pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) "L-phenylalanine:pyruvate transaminase activity"^^xsd:string) AnnotationAssertion( "phenylalanine(histidine) aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.58"^^xsd:string) "phenylalanine(histidine):pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) "L-histidine:pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.58"^^xsd:string) Annotation( "GOC:kad"^^xsd:string) "histidine:pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.58"^^xsd:string) "L-phenylalanine(L-histidine):pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) "histidine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.58"^^xsd:string) "phenylalanine (histidine) aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.58"^^xsd:string) "phenylalanine(histidine) transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.58"^^xsd:string) Annotation( "MetaCyc:2.6.1.58-RXN"^^xsd:string) "Catalysis of the reaction: pyruvate + L-phenylalanine = phenylpyruvate + L-alanine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.60"^^xsd:string) Annotation( "MetaCyc:2.6.1.60-RXN"^^xsd:string) "Catalysis of the reaction: glyoxylate + an aromatic amino acid = L-glycine + an aromatic oxo acid."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.60"^^xsd:string) "aromatic-amino-acid:glyoxylate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aromatic-amino-acid-glyoxylate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.60"^^xsd:string) "aromatic-amino-acid--glyoxylate aminotransferase activity"^^xsd:string) AnnotationAssertion( "aromatic-amino-acid-glyoxylate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "kynurenine-glyoxylate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.63"^^xsd:string) "kynurenine--glyoxylate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.63"^^xsd:string) "L-kynurenine:glyoxylate aminotransferase (cyclizing)"^^xsd:string) AnnotationAssertion( "kynurenine-glyoxylate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.63"^^xsd:string) Annotation( "RHEA:19252"^^xsd:string) "Catalysis of the reaction: L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.64"^^xsd:string) "glutamine transaminase K activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.64"^^xsd:string) Annotation( "RHEA:17596"^^xsd:string) "Catalysis of the reaction: keto-phenylpyruvate + L-glutamine = 2-oxoglutaramate + L-phenylalanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.64"^^xsd:string) "glutamine--phenylpyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamine-phenylpyruvate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.64"^^xsd:string) "L-glutamine:phenylpyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion( "glutamine-phenylpyruvate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.65"^^xsd:string) Annotation( "MetaCyc:2.6.1.65-RXN"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + 3-amino-6-acetamidohexanoate = L-glutamate + 3-oxo-6-acetamidohexanoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.65"^^xsd:string) "6-acetamido-3-aminohexanoate:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.65"^^xsd:string) "epsilon-acetyl-beta-lysine aminotransferase activity"^^xsd:string) AnnotationAssertion( "N6-acetyl-beta-lysine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.65"^^xsd:string) "N(6)-acetyl-beta-lysine aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N6-acetyl-beta-lysine transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "aspartate-phenylpyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.70"^^xsd:string) "L-aspartate:phenylpyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aspartate-phenylpyruvate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.70"^^xsd:string) Annotation( "RHEA:14100"^^xsd:string) "Catalysis of the reaction: keto-phenylpyruvate + L-aspartate = L-phenylalanine + oxaloacetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.70"^^xsd:string) "aspartate--phenylpyruvate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.72"^^xsd:string) "D-4-hydroxyphenylglycine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.72"^^xsd:string) "D-hydroxyphenylglycine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.72"^^xsd:string) Annotation( "RHEA:15592"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + D-4-hydroxyphenylglycine = 4-hydroxyphenylglyoxylate + L-glutamate."^^xsd:string) AnnotationAssertion(rdfs:label "D-4-hydroxyphenylglycine transaminase activity"^^xsd:string) AnnotationAssertion( "D-4-hydroxyphenylglycine aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.99.1"^^xsd:string) "diphosphate:microsomal-membrane-protein O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.99.1"^^xsd:string) Annotation( "MetaCyc:2.7.99.1-RXN"^^xsd:string) "Catalysis of the reaction: microsomal-membrane protein + diphosphate = diphosphate + O-phospho-microsomal-membrane protein."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.99.1"^^xsd:string) "pyrophosphate:protein phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.99.1"^^xsd:string) "triphosphate:microsomal-membrane-protein phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "diphosphate-protein phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.99.1"^^xsd:string) "DiPPT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.99.1"^^xsd:string) "pyrophosphate-protein phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.99.1"^^xsd:string) "triphosphate-protein phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.31"^^xsd:string) "hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.31"^^xsd:string) "hydroxymethylglutaryl-CoA reductase (NADPH) kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.31"^^xsd:string) "reductase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.31"^^xsd:string) "AMPK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.31"^^xsd:string) "3-hydroxy-3-methylglutaryl coenzyme A reductase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.31"^^xsd:string) "hydroxymethylglutaryl-CoA reductase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.31"^^xsd:string) "HMG-CoA reductase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.31"^^xsd:string) "3-hydroxy-3-methylglutaryl-CoA reductase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.31"^^xsd:string) Annotation( "MetaCyc:2.7.1.109-RXN"^^xsd:string) "Catalysis of the reaction: [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] + ATP = [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] phosphate + ADP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.31"^^xsd:string) "beta-hydroxy-beta-methylglutaryl-CoA reductase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.31"^^xsd:string) "STK29"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.31"^^xsd:string) "hydroxymethylglutaryl-CoA reductase (NADPH2) kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.31"^^xsd:string) "hydroxymethylglutaryl coenzyme A reductase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.31"^^xsd:string) "ATP:hydroxymethylglutaryl-CoA reductase (NADPH) phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.4"^^xsd:string) "BCKD kinase activity"^^xsd:string) AnnotationAssertion( "[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.4"^^xsd:string) "3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.4"^^xsd:string) "Catalysis of the reaction: ATP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) = ADP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.4"^^xsd:string) "BCODH kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.4"^^xsd:string) "branched-chain keto acid dehydrogenase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.4"^^xsd:string) "branched-chain oxo acid dehydrogenase kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.4"^^xsd:string) "ATP:3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.4"^^xsd:string) "BCK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.4"^^xsd:string) "branched-chain alpha-ketoacid dehydrogenase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.4"^^xsd:string) "STK2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.4"^^xsd:string) "branched-chain 2-oxo acid dehydrogenase kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.121"^^xsd:string) "phosphoenolpyruvate:glycerone phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.121"^^xsd:string) Annotation( "RHEA:18384"^^xsd:string) "Catalysis of the reaction: glycerone + phosphoenolpyruvate = glycerone phosphate + pyruvate."^^xsd:string) AnnotationAssertion(rdfs:label "phosphoenolpyruvate-glycerone phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.134"^^xsd:string) "ATP:1D-myo-inositol-3,4,5,6-tetrakisphosphate 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.134"^^xsd:string) "inositol-trisphosphate 5-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.134"^^xsd:string) "1D-myo-inositol-trisphosphate 5-kinase activity"^^xsd:string) AnnotationAssertion( "inositol-tetrakisphosphate 1-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.134"^^xsd:string) "1D-myo-inositol-tetrakisphosphate 1-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.134"^^xsd:string) "1D-myo-inositol-trisphosphate 6-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.134"^^xsd:string) "inositol-trisphosphate 6-kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol tetrakisphosphate 1-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.134"^^xsd:string) Annotation( "MetaCyc:2.7.1.134-RXN"^^xsd:string) "Catalysis of the reaction: 1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP."^^xsd:string) AnnotationAssertion( "inositol 3,4,5,6-tetrakisphosphate 1-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.140"^^xsd:string) Annotation( "MetaCyc:2.7.1.140-RXN"^^xsd:string) "Catalysis of the reaction: 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP."^^xsd:string) AnnotationAssertion( "1D-myo-inositol-tetrakisphosphate 5-kinase activity"^^xsd:string) AnnotationAssertion( "inositol 1,3,4,6-tetrakisphosphate 5-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.140"^^xsd:string) "ATP:1D-myo-inositol-1,3,4,6-tetrakisphosphate 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion( "inositol-tetrakisphosphate 5-kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol tetrakisphosphate 5-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.142"^^xsd:string) Annotation( "RHEA:21291"^^xsd:string) "Catalysis of the reaction: sn-glycerol 3-phosphate + D-glucose = D-glucose 6-phosphate + glycerol."^^xsd:string) AnnotationAssertion(rdfs:label "glycerol-3-phosphate-glucose phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.142"^^xsd:string) "sn-glycerol-3-phosphate:D-glucose 6-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.61"^^xsd:string) "hexose phosphate:hexose phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.61"^^xsd:string) Annotation( "MetaCyc:2.7.1.61-RXN"^^xsd:string) "Catalysis of the reaction: D-hexose + acyl phosphate = D-hexose phosphate + an acid."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.61"^^xsd:string) "acyl-phosphate:D-hexose phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acyl-phosphate-hexose phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphoramidate-hexose phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.62"^^xsd:string) Annotation( "MetaCyc:2.7.1.62-RXN"^^xsd:string) "Catalysis of the reaction: hexose + phosphoramidate = hexose 1-phosphate + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.62"^^xsd:string) "phosphoramidate:hexose 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.62"^^xsd:string) "phosphoramidate-hexose transphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.62"^^xsd:string) "phosphoramidic-hexose transphosphorylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.63"^^xsd:string) "polyphosphate-glucose 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.63"^^xsd:string) "polyphosphate:D-glucose 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.63"^^xsd:string) "polyphosphate glucokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.63"^^xsd:string) Annotation( "MetaCyc:2.7.1.63-RXN"^^xsd:string) "Catalysis of the reaction: beta-D-glucose + long chain polyphosphate = glucose-6-phosphate + long chain polyphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "polyphosphate-glucose phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.63"^^xsd:string) "polyphosphate-D-(+)-glucose-6-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.79"^^xsd:string) "diphosphate:glycerol 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.79"^^xsd:string) "pyrophosphate--glycerol phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.79"^^xsd:string) "PPi-glycerol phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.79"^^xsd:string) Annotation( "RHEA:13692"^^xsd:string) "Catalysis of the reaction: glycerol + diphosphate = glycerol 1-phosphate + H(+) + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "diphosphate-glycerol phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.80"^^xsd:string) Annotation( "RHEA:23767"^^xsd:string) "Catalysis of the reaction: L-serine + diphosphate = O-phospho-L-serine + H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.80"^^xsd:string) "diphosphate:L-serine O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.80"^^xsd:string) "pyrophosphate--serine phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.80"^^xsd:string) "pyrophosphate-L-serine phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "diphosphate-serine phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.88"^^xsd:string) Annotation( "RHEA:16284"^^xsd:string) "Catalysis of the reaction: ATP + dihydrostreptomycin 6-phosphate = ADP + dihydrostreptomycin 3'alpha,6-bisphosphate + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.88"^^xsd:string) "dihydrostreptomycin 6-phosphate kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "dihydrostreptomycin-6-phosphate 3'-alpha-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.88"^^xsd:string) "dihydrostreptomycin-6-phosphate 3'alpha-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.88"^^xsd:string) "ATP:dihydrostreptomycin-6-phosphate 3'alpha-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.88"^^xsd:string) "ATP:dihydrostreptomycin-6-P 3'alpha-phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.90"^^xsd:string) Annotation( "MetaCyc:2.7.1.90-RXN"^^xsd:string) "Catalysis of the reaction: fructose-6-phosphate + diphosphate = phosphate + fructose-1,6-bisphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.90"^^xsd:string) "6-phosphofructokinase (diphosphate) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.90"^^xsd:string) "diphosphate:D-fructose-6-phosphate 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.90"^^xsd:string) "pyrophosphate--fructose 6-phosphate 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.90"^^xsd:string) "pyrophosphate-dependent 6-phosphofructose-1-kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "diphosphate-fructose-6-phosphate 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.90"^^xsd:string) "diphosphate-dependent 6-phosphofructose-1-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.90"^^xsd:string) "pyrophosphate-fructose 6-phosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.90"^^xsd:string) "inorganic pyrophosphate-dependent phosphofructokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.90"^^xsd:string) "6-phosphofructokinase (pyrophosphate) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.90"^^xsd:string) "inorganic pyrophosphate-phosphofructokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.90"^^xsd:string) "pyrophosphate-dependent phosphofructo-1-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.4.17"^^xsd:string) "diphosphoglycerate-polyphosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.17"^^xsd:string) Annotation( "MetaCyc:2.7.4.17-RXN"^^xsd:string) "Catalysis of the reaction: long-chain-polyphosphate + 3-phospho-D-glyceroyl-phosphate = long-chain-polyphosphate + 3-phosphoglycerate."^^xsd:string) AnnotationAssertion(rdfs:label "3-phosphoglyceroyl-phosphate-polyphosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.17"^^xsd:string) "1,3-diphosphoglycerate-polyphosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.17"^^xsd:string) "3-phospho-D-glyceroyl-phosphate:polyphosphate phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.4.19"^^xsd:string) Annotation( "RHEA:11399"^^xsd:string) "Catalysis of the reaction: 2'-deoxy-5-methyl-5'-cytidylate + ATP = 5-methyldeoxycytidine diphosphate + ADP + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.19"^^xsd:string) "ATP:5-methyldeoxycytidine-5'-phosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "5-methyldeoxycytidine-5'-phosphate kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.4.20"^^xsd:string) "dolichyl-diphosphate:polyphosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dolichyl-diphosphate-polyphosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.20"^^xsd:string) Annotation( "MetaCyc:2.7.4.20-RXN"^^xsd:string) "Catalysis of the reaction: dolichyl diphosphate + long-chain-polyphosphate = dolichol-phosphate + long-chain-polyphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.20"^^xsd:string) "dolichylpyrophosphate:polyphosphate phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.11"^^xsd:string) "UTP:alpha-D-xylose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.11"^^xsd:string) Annotation( "MetaCyc:2.7.7.11-RXN"^^xsd:string) "Catalysis of the reaction: alpha-D-xylose 1-phosphate + UTP = UDP-D-xylose + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.11"^^xsd:string) "xylose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.11"^^xsd:string) "UTP-xylose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UTP:xylose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.11"^^xsd:string) "xylose 1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.11"^^xsd:string) "UDP-xylose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.11"^^xsd:string) "uridylyltransferase, xylose 1-phosphate"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.11"^^xsd:string) "uridine diphosphoxylose pyrophosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.28"^^xsd:string) "NTP:alpha-D-aldose-1-phosphate nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion( "NDP-hexose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.28"^^xsd:string) "NTP:hexose-1-phosphate nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion( "NDP-hexose diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.28"^^xsd:string) Annotation( "MetaCyc:2.7.7.28-RXN"^^xsd:string) "Catalysis of the reaction: hexose 1-phosphate + nucleoside triphosphate = NDP-hexose + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.28"^^xsd:string) "guanosine diphosphohexose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.28"^^xsd:string) "NDP hexose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.28"^^xsd:string) "GTP:alpha-D-hexose-1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.28"^^xsd:string) "hexose 1-phosphate nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.28"^^xsd:string) "hexose 1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.28"^^xsd:string) "nucleoside diphosphohexose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion( "hexose-1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion( "GTP:hexose-1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.28"^^xsd:string) "hexose nucleotidylating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.28"^^xsd:string) "GDP hexose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.28"^^xsd:string) "nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.30"^^xsd:string) "GDP-L-fucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.30"^^xsd:string) "guanosine diphosphate L-fucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.30"^^xsd:string) "GDP-fucose diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.30"^^xsd:string) "GTP:L-fucose-1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.30"^^xsd:string) "GDP-fucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.30"^^xsd:string) Annotation( "RHEA:13552"^^xsd:string) "Catalysis of the reaction: beta-L-fucose 1-phosphate + GTP = diphosphate + GDP-L-fucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.30"^^xsd:string) "GDP fucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.30"^^xsd:string) "GTP:beta-L-fucose-1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion( "GTP:fucose-1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "fucose-1-phosphate guanylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.32"^^xsd:string) "dTDP-galactose diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.32"^^xsd:string) "galactose 1-phosphate thymidylyl transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactose-1-phosphate thymidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.32"^^xsd:string) "dTTP:alpha-D-galactose-1-phosphate thymidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.32"^^xsd:string) "thymidine triphosphate:alpha-D-galactose 1-phosphate thymidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.32"^^xsd:string) "dTDP-galactose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.32"^^xsd:string) "thymidine diphosphogalactose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.32"^^xsd:string) "dTDP galactose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.32"^^xsd:string) Annotation( "RHEA:17168"^^xsd:string) "Catalysis of the reaction: alpha-D-galactose 1-phosphate + dTTP = diphosphate + dTDP-D-galactose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.33"^^xsd:string) "CDP-glucose diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.33"^^xsd:string) "CTP:alpha-D-glucose-1-phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.33"^^xsd:string) "CTP:D-glucose-1-phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion( "CTP:glucose-1-phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.33"^^xsd:string) "cytidine diphosphoglucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.33"^^xsd:string) "CDP-glucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.33"^^xsd:string) "cytidine diphosphate-D-glucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucose-1-phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.33"^^xsd:string) Annotation( "RHEA:18216"^^xsd:string) "Catalysis of the reaction: alpha-D-glucose 1-phosphate + CTP = CDP-D-glucose + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.33"^^xsd:string) "CDP glucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.33"^^xsd:string) "cytidine diphosphate glucose pyrophosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.34"^^xsd:string) "GTP:alpha-D-glucose-1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion( "GTP:glucose-1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.34"^^xsd:string) "GDP glucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.34"^^xsd:string) Annotation( "RHEA:10711"^^xsd:string) "Catalysis of the reaction: alpha-D-glucose 1-phosphate + GTP = diphosphate + GDP-D-glucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.34"^^xsd:string) "GDP-glucose diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.34"^^xsd:string) "guanosine diphosphoglucose pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucose-1-phosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.34"^^xsd:string) "GDP-glucose pyrophosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.35"^^xsd:string) "ADP-ribose phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.35"^^xsd:string) "ADP ribose phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.35"^^xsd:string) "adenosine diphosphoribose phosphorylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ribose-5-phosphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.35"^^xsd:string) Annotation( "RHEA:14532"^^xsd:string) "Catalysis of the reaction: D-ribose 5-phosphate + ADP + H(+) = ADP-ribose + phosphate."^^xsd:string) AnnotationAssertion( "ADP:ribose-5-phosphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.35"^^xsd:string) "ADP:D-ribose-5-phosphate adenylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.36"^^xsd:string) "sugar-1-phosphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aldose-1-phosphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.36"^^xsd:string) "ADP-aldose phosphorylase activity"^^xsd:string) AnnotationAssertion( "ADP:aldose-1-phosphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.36"^^xsd:string) "ADPaldose phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.36"^^xsd:string) "adenosine diphosphate glucose:orthophosphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.36"^^xsd:string) "ADP sugar phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.36"^^xsd:string) "ADP:alpha-D-aldose-1-phosphate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.36"^^xsd:string) "ADP-sugar phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.36"^^xsd:string) "adenosine diphosphosugar phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.36"^^xsd:string) Annotation( "MetaCyc:2.7.7.36-RXN"^^xsd:string) "Catalysis of the reaction: aldose 1-phosphate + ADP = phosphate + ADP-aldose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.37"^^xsd:string) "NDP:alpha-D-aldose-1-phosphate nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.37"^^xsd:string) "sugar nucleotide phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.37"^^xsd:string) "sugar-1-phosphate nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.37"^^xsd:string) "NDP:aldose-1-phosphate nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.37"^^xsd:string) "NDP-aldose phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.37"^^xsd:string) Annotation( "MetaCyc:2.7.7.37-RXN"^^xsd:string) "Catalysis of the reaction: aldose 1-phosphate + NDP = phosphate + NDP-aldose."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.37"^^xsd:string) "NDPaldose phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.37"^^xsd:string) "sugar phosphate nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.37"^^xsd:string) "NDP-sugar phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.37"^^xsd:string) "glucose 1-phosphate inosityltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.37"^^xsd:string) "nucleoside diphosphate sugar:orthophosphate nucleotidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.37"^^xsd:string) "NDP sugar phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.37"^^xsd:string) "nucleoside diphosphosugar phosphorylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aldose-1-phosphate nucleotidyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.39"^^xsd:string) "cytidine diphosphate glycerol pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.39"^^xsd:string) "Gro-PCT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.39"^^xsd:string) "CTP:sn-glycerol-3-phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.39"^^xsd:string) "cytidine diphosphoglycerol pyrophosphorylase activity"^^xsd:string) AnnotationAssertion( "CTP:glycerol-3-phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.39"^^xsd:string) "CDP-glycerol diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.39"^^xsd:string) Annotation( "RHEA:13364"^^xsd:string) "Catalysis of the reaction: sn-glycerol 3-phosphate + CTP = CDP-glycerol + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "glycerol-3-phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.39"^^xsd:string) "CTP:glycerol 3-phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.39"^^xsd:string) "CDP-glycerol pyrophosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.40"^^xsd:string) "cytidine diphosphate ribitol pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-ribitol-5-phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.40"^^xsd:string) "CDP-ribitol pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.40"^^xsd:string) "CDP ribitol pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.40"^^xsd:string) "cytidine diphosphoribitol pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.40"^^xsd:string) "CDP-ribitol diphosphorylase activity"^^xsd:string) AnnotationAssertion( "CTP:D-ribitol-5-phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.40"^^xsd:string) Annotation( "RHEA:12459"^^xsd:string) "Catalysis of the reaction: D-ribitol 5-phosphate + CTP = CDP-ribitol + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.40"^^xsd:string) "ribitol 5-phosphate cytidylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.44"^^xsd:string) "uridine diphosphoglucuronic pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.44"^^xsd:string) "UTP:1-phospho-alpha-D-glucuronate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.44"^^xsd:string) Annotation( "RHEA:16328"^^xsd:string) "Catalysis of the reaction: 1-phospho-alpha-D-glucuronate + UTP = diphosphate + UDP-alpha-D-glucuronate."^^xsd:string) AnnotationAssertion(rdfs:label "glucuronate-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.44"^^xsd:string) "UDP-glucuronic acid pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.44"^^xsd:string) "UDP-D-glucuronic acid pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.44"^^xsd:string) "UDP-glucuronate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion( "UTP:glucuronate-1-phosphate uridylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "guanosine-triphosphate guanylyltransferase activity"^^xsd:string) AnnotationAssertion( "GTP:GTP guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.45"^^xsd:string) Annotation( "RHEA:18156"^^xsd:string) "Catalysis of the reaction: 2 GTP = P(1),P(4)-bis(5'-guanosyl) tetraphosphate + diphosphate + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.51"^^xsd:string) "adenylylsulfate:ammonia adenylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "adenylylsulfate-ammonia adenylyltransferase activity"^^xsd:string) AnnotationAssertion( "adenylylsulphate-ammonia adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.51"^^xsd:string) Annotation( "RHEA:19200"^^xsd:string) "Catalysis of the reaction: 5'-adenylyl sulfate + NH(4)(+) = adenosine 5'-phosphoramidate + 2 H(+) + sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.51"^^xsd:string) "APSAT"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.57"^^xsd:string) "CTP:N-methylethanolamine-phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion( "CTP:N-methylphosphoethanolamine cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-methylphosphoethanolamine cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.57"^^xsd:string) Annotation( "RHEA:10579"^^xsd:string) "Catalysis of the reaction: N-methylethanolamine phosphate + CTP = CDP-N-methylethanolamine + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.57"^^xsd:string) "monomethylethanolamine phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.57"^^xsd:string) "CTP:P-MEA cytidylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.10"^^xsd:string) Annotation( "RHEA:21227"^^xsd:string) "Catalysis of the reaction: CDP-choline + sphingosine = CMP + H(+) + sphingosyl-phosphocholine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.10"^^xsd:string) "CDP-choline-sphingosine cholinephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.10"^^xsd:string) "phosphorylcholine-sphingosine transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sphingosine cholinephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.10"^^xsd:string) "cytidine diphosphocholine-sphingosine cholinephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.10"^^xsd:string) "CDP-choline:sphingosine cholinephosphotransferase activity"^^xsd:string) AnnotationAssertion( "sphingosine choline phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.12"^^xsd:string) Annotation( "MetaCyc:2.7.8.12-RXN"^^xsd:string) "Catalysis of the reaction: glycerophosphate(n) + CDP-glycerol = glycerophosphate(n+1) + CMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.12"^^xsd:string) "CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.12"^^xsd:string) "glycerophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.12"^^xsd:string) "poly(glycerol phosphate) polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.12"^^xsd:string) "teichoic acid glycerol transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.12"^^xsd:string) "teichoic-acid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.12"^^xsd:string) "CDPglycerol glycerophosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.12"^^xsd:string) "CGPTase activity"^^xsd:string) AnnotationAssertion(rdfs:label "CDP-glycerol glycerophosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.12"^^xsd:string) "cytidine diphosphoglycerol glycerophosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.14"^^xsd:string) "teichoate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.14"^^xsd:string) "CDP-ribitol:poly(ribitol phosphate) ribitolphosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.14"^^xsd:string) "polyribitol phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.14"^^xsd:string) Annotation( "MetaCyc:2.7.8.14-RXN"^^xsd:string) "Catalysis of the reaction: ribitol phosphate(n) + CDP-ribitol = ribitol phosphate(n+1) + CMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.14"^^xsd:string) "CDPribitol ribitolphosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.14"^^xsd:string) "teichoic-acid synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "CDP-ribitol ribitolphosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.14"^^xsd:string) "teichoate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.14"^^xsd:string) "polyribitol phosphate polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.14"^^xsd:string) "poly(ribitol phosphate) synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-galactose-UDP-N-acetylglucosamine galactose phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.18"^^xsd:string) "UDPgalactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.18"^^xsd:string) "uridine diphosphogalactose-uridine diphosphoacetylglucosamine galactose-1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.18"^^xsd:string) Annotation( "RHEA:22443"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + UDP-D-galactose = H(+) + UDP-N-acetyl-6-(D-galactose-1-phospho)-D-glucosamine + UMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.18"^^xsd:string) "galactose-1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.18"^^xsd:string) "UDP-galactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.18"^^xsd:string) "galactosyl phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.18"^^xsd:string) "UDPgalactose-UDP-N-acetylglucosamine galactose phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-glucose-glycoprotein glucose phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.19"^^xsd:string) Annotation( "MetaCyc:2.7.8.19-RXN"^^xsd:string) "Catalysis of the reaction: glycoprotein D-mannose + UDP-D-glucose = glycoprotein 6-(D-glucose-1-phospho)-D-mannose + UMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.19"^^xsd:string) "GlcPTase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.19"^^xsd:string) "UDPglucose:glycoprotein-D-mannose glucosephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.19"^^xsd:string) "UDP-glucose:glycoprotein-D-mannose glucosephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.19"^^xsd:string) "Glc-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.19"^^xsd:string) "UDPglucose-glycoprotein glucose phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.19"^^xsd:string) "UDP-glucose:glycoprotein glucose-1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.19"^^xsd:string) "uridine diphosphoglucose-glycoprotein glucose-1-phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.22"^^xsd:string) "CDP-choline-1-alkenyl-2-acyl-glycerol phosphocholinetransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-alkenyl-2-acylglycerol choline phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.22"^^xsd:string) "CDP-choline:1-alkenyl-2-acylglycerol cholinephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.22"^^xsd:string) Annotation( "MetaCyc:2.7.8.22-RXN"^^xsd:string) "Catalysis of the reaction: 1-alkenyl-2-acylglycerol + CDP-choline = plasmenylcholine + CMP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.6"^^xsd:string) "poly(isoprenol)-phosphate galactose phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.6"^^xsd:string) "poly(isoprenyl)phosphate galactosephosphatetransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.6"^^xsd:string) "poly(isoprenol)-phosphate galactosephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.6"^^xsd:string) Annotation( "RHEA:11655"^^xsd:string) "Catalysis of the reaction: all-trans-undecaprenyl phosphate + UDP-D-galactose = alpha-D-galactosyl-diphosphoundecaprenol + UMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.6"^^xsd:string) "UDP-galactose:undecaprenyl-phosphate galactose phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.6"^^xsd:string) "undecaprenyl phosphate galactosyl-1-phosphate transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "undecaprenyl-phosphate galactose phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.9"^^xsd:string) "GDP-mannose:phosphomannan mannose phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphomannan mannosephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.9"^^xsd:string) Annotation( "MetaCyc:2.7.8.9-RXN"^^xsd:string) "Catalysis of the reaction: phosphomannan(n) + GDP-mannose = phosphomannan(n+1) + GMP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.1.5"^^xsd:string) "TSR"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.5"^^xsd:string) "thiosulfate:dithioerythritol sulfurtransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.5"^^xsd:string) "thiosulfate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.5"^^xsd:string) Annotation( "MetaCyc:2.8.1.5-RXN"^^xsd:string) "Catalysis of the reaction: dithioerythritol + thiosulfate = hydrogen sulfide + dithioerythritol disulfide + sulfite."^^xsd:string) AnnotationAssertion( "thiosulphate-dithiol sulphurtransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiosulfate-dithiol sulfurtransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.19"^^xsd:string) "3'-phosphoadenylyl-sulfate:triglucosyl-1-O-alkyl-2-O-acylglycerol 6-sulfotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "triglucosylalkylacylglycerol sulfotransferase activity"^^xsd:string) AnnotationAssertion( "triglucosylalkylacylglycerol sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.19"^^xsd:string) Annotation( "MetaCyc:2.8.2.19-RXN"^^xsd:string) "Catalysis of the reaction: alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + 3'-phosphoadenosine 5'-phosphosulfate = 6-sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + adenosine 3',5'-bisphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.19"^^xsd:string) "triglucosylmonoalkylmonoacyl sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.24"^^xsd:string) "3'-phosphoadenosine-5'-phosphosulfate:desulfoglucosinolate sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.24"^^xsd:string) "3'-phosphoadenylyl-sulfate:desulfoglucosinolate sulfotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "desulfoglucosinolate sulfotransferase activity"^^xsd:string) AnnotationAssertion( "desulphoglucosinolate sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.24"^^xsd:string) "PAPS-desulfoglucosinolate sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.24"^^xsd:string) Annotation( "RHEA:20284"^^xsd:string) "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + desulfoglucotropeolin = adenosine 3',5'-diphosphate + glucotropeolin + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.26"^^xsd:string) "3'-phosphoadenylyl-sulfate:quercetin-3-sulfate 3'-sulfotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "quercetin-3-sulfate 3'-sulfotransferase activity"^^xsd:string) AnnotationAssertion( "quercetin-3-sulphate 3'-sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.26"^^xsd:string) Annotation( "RHEA:22507"^^xsd:string) "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H(+) + quercetin 3,3'-disulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.26"^^xsd:string) "flavonol 3'-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.26"^^xsd:string) "3'-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.26"^^xsd:string) "PAPS:flavonol 3-sulfate 3'-sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "quercetin-3-sulfate 4'-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.27"^^xsd:string) Annotation( "RHEA:17208"^^xsd:string) "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H(+) + quercetin 3,4'-disulfate."^^xsd:string) AnnotationAssertion( "quercetin-3-sulphate 4'-sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.27"^^xsd:string) "PAPS:flavonol 3-sulfate 4'-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.27"^^xsd:string) "flavonol 4'-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.27"^^xsd:string) "3'-phosphoadenylyl-sulfate:quercetin-3-sulfate 4'-sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.28"^^xsd:string) "7-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.28"^^xsd:string) "3'-phosphoadenylyl-sulfate:quercetin-3,3'-bissulfate 7-sulfotransferase activity"^^xsd:string) AnnotationAssertion( "quercetin-3,3'-bissulphate 7-sulphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "quercetin-3,3'-bissulfate 7-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.28"^^xsd:string) "PAPS:flavonol 3,3'/3,4'-disulfate 7-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.28"^^xsd:string) "flavonol 7-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.28"^^xsd:string) Annotation( "MetaCyc:2.8.2.28-RXN"^^xsd:string) "Catalysis of the reaction: quercetin 3,3'-bissulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,3',7-trissulfate + adenosine 3',5'-bisphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-N-acetylgalactosamine-4-sulfate sulfotransferase activity"^^xsd:string) AnnotationAssertion( "UDP-N-acetylgalactosamine-4-sulphate sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.7"^^xsd:string) "3'-phosphoadenylyl-sulfate:UDP-N-acetyl-D-galactosamine-4-sulfate 6-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.7"^^xsd:string) "uridine diphosphoacetylgalactosamine 4-sulfate sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.7"^^xsd:string) "uridine diphospho-N-acetylgalactosamine 4-sulfate sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.7"^^xsd:string) Annotation( "RHEA:14340"^^xsd:string) "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + UDP-N-acetyl-D-galactosamine 4-sulfate = adenosine 3',5'-diphosphate + H(+) + UDP-N-acetyl-D-galactosamine 4,6-disulfate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.3.13"^^xsd:string) "succinate:(S)-3-hydroxy-3-methylglutarate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.13"^^xsd:string) Annotation( "MetaCyc:2.8.3.13-RXN"^^xsd:string) "Catalysis of the reaction: (S)-3-hydroxy-3-methylglutarate + succinyl-CoA = 3-hydroxy-3-methyl-glutaryl-CoA + succinate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.13"^^xsd:string) "dicarboxyl-CoA:dicarboxylic acid coenzyme A transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "succinate-hydroxymethylglutarate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.13"^^xsd:string) "hydroxymethylglutarate coenzyme A-transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.3.7"^^xsd:string) "succinyl coenzyme A-citramalyl coenzyme A transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.7"^^xsd:string) "succinyl-CoA:citramalate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.7"^^xsd:string) "itaconate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.7"^^xsd:string) "citramalate coenzyme A-transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "succinate-citramalate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.7"^^xsd:string) Annotation( "MetaCyc:2.8.3.7-RXN"^^xsd:string) "Catalysis of the reaction: S-citramalate + succinyl-CoA = citramalyl-CoA + succinate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "butyrate-acetoacetate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.9"^^xsd:string) "butyryl-CoA-acetoacetate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.9"^^xsd:string) "butanoyl-CoA:acetoacetate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.9"^^xsd:string) "butyryl coenzyme A-acetoacetate coenzyme A-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.9"^^xsd:string) Annotation( "RHEA:12964"^^xsd:string) "Catalysis of the reaction: acetoacetate + butanoyl-CoA = acetoacetyl-CoA + butanoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.23"^^xsd:string) "monoglyceride lipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.23"^^xsd:string) "monoacylglycerolipase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acylglycerol lipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.23"^^xsd:string) "monoglyceride hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.23"^^xsd:string) "monoacylglycerol lipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.23"^^xsd:string) "monoglyceridase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.23"^^xsd:string) "glycerol-ester acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.23"^^xsd:string) "monoacylglycerol hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.23"^^xsd:string) Annotation( "MetaCyc:3.1.1.23-RXN"^^xsd:string) "Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.23"^^xsd:string) "monoglyceridyllipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.23"^^xsd:string) "fatty acyl monoester lipase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.54"^^xsd:string) "5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene O-acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.54"^^xsd:string) Annotation( "RHEA:11551"^^xsd:string) "Catalysis of the reaction: 5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene + H(2)O = 5-(4-hydroxy-but-1-ynyl)-2,2'-bithiophene + acetate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.54"^^xsd:string) "acetoxybutynylbithiophene esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.54"^^xsd:string) "5-(4-acetoxy-1-butynyl)-2,2'-bithiophene:acetate esterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetoxybutynylbithiophene deacetylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methylumbelliferyl-acetate deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.56"^^xsd:string) "4-methylumbelliferyl-acetate acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.56"^^xsd:string) "esterase D activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.56"^^xsd:string) Annotation( "RHEA:12211"^^xsd:string) "Catalysis of the reaction: 4-methylumbelliferyl acetate + H(2)O = 4-methylumbelliferone + acetate + H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-acetylgalactosaminoglycan deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.58"^^xsd:string) "polysaccharide deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.58"^^xsd:string) "N-acetyl-D-galactosaminoglycan acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.58"^^xsd:string) Annotation( "MetaCyc:3.1.1.58-RXN"^^xsd:string) "Catalysis of the reaction: H2O + N-acetyl-D-galactosaminoglycan = acetate + D-galactosaminoglycan."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.58"^^xsd:string) "Vi-polysaccharide deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.58"^^xsd:string) "N-acetyl galactosaminoglycan deacetylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "KEGG:R02368"^^xsd:string) "retinyl-palmitate palmitohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.64"^^xsd:string) "all-trans-retinyl-palmitate hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:3.1.1.64-RXN"^^xsd:string) Annotation( "RHEA:13936"^^xsd:string) "Catalysis of the reaction: all-trans-retinyl palmitate + H2O = all-trans-retinol + H+ + palmitate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.64"^^xsd:string) "all-trans-retinyl-palmitate acylhydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.66"^^xsd:string) Annotation( "RHEA:16316"^^xsd:string) "Catalysis of the reaction: 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene + H(2)O = 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + acetate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.66"^^xsd:string) "5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene acetylhydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.66"^^xsd:string) "diacetoxybutynylbithiophene acetate esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.66"^^xsd:string) "3,4-diacetoxybutinylbithiophene:4-acetate esterase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.71"^^xsd:string) "2-acetyl-1-alkyl-sn-glycerol acetylhydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetylalkylglycerol acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.71"^^xsd:string) "alkylacetylglycerol acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.71"^^xsd:string) Annotation( "RHEA:11555"^^xsd:string) "Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycerol + H(2)O = 1-alkyl-sn-glycerol + acetate + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.2.18"^^xsd:string) "ADP-dependent propionyl coenzyme A hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.18"^^xsd:string) "ADP-dependent-short-chain-acyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.18"^^xsd:string) "ADP-dependent propionyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.18"^^xsd:string) "ADP-dependent propionyl-CoA thioesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.18"^^xsd:string) "ADP-dependent short-chain acyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ADP-dependent short-chain-acyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.18"^^xsd:string) Annotation( "MetaCyc:3.1.2.18-RXN"^^xsd:string) "Catalysis of the reaction: H2O + a short-chain acyl-CoA = a short-chain carboxylate + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.18"^^xsd:string) "ADP-dependent short-chain acyl-CoA thioesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.18"^^xsd:string) "ADP-dependent short-chain acyl coenzyme A hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ADP-dependent medium-chain-acyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "ADP-dependent medium-chain hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "ADP-dependent medium-chain acyl-thioester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "ADP-dependent-medium-chain-acyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "ADP-dependent medium-chain acyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "ADP-dependent myristoyl-CoA thioesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) Annotation( "MetaCyc:3.1.2.19-RXN"^^xsd:string) "Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA. Requires ADP."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "ADP-dependent medium-chain acyl coenzyme A hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "lauroyl-ACP hydrolase activity"^^xsd:string) AnnotationAssertion( "lauroyl-[acyl-carrier-protein] hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.21"^^xsd:string) "lauryl-acyl-carrier protein hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dodecanoyl-[acyl-carrier-protein] hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.21"^^xsd:string) "dodecyl-[acyl-carrier protein] hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.21"^^xsd:string) "dodecanoyl-acyl-carrier-protein hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.21"^^xsd:string) "lauryl-acyl-carrier-protein hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.21"^^xsd:string) "lauryl-[acyl-carrier protein] hydrolase activity"^^xsd:string) AnnotationAssertion( "dodecanoyl-[acyl-carrier protein] hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.21"^^xsd:string) Annotation( "MetaCyc:3.1.2.21-RXN"^^xsd:string) "Catalysis of the reaction: H2O + dodecanoyl-[acyl-carrier protein] = dodecanoate + [acyl-carrier protein]."^^xsd:string) AnnotationAssertion( "dodecanoyl-ACP hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.21"^^xsd:string) "dodecyl-acyl-carrier protein hydrolase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.14"^^xsd:string) Annotation( "RHEA:16084"^^xsd:string) "Catalysis of the reaction: S-methyl-3-phospho-1-thio-D-glycerate + H(2)O = S-methyl-1-thio-D-glycerate + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "methylphosphothioglycerate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.14"^^xsd:string) "methylthiophosphoglycerate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.14"^^xsd:string) "S-methyl-3-phospho-1-thio-D-glycerate phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.40"^^xsd:string) "1-guanidino-1-deoxy-scyllo-inositol-4-phosphate 4-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.40"^^xsd:string) "1-guanidino-scyllo-inositol 4-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.40"^^xsd:string) "1-guanidino-1-deoxy-scyllo-inositol-4-P phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "guanidinodeoxy-scyllo-inositol-4-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.40"^^xsd:string) Annotation( "RHEA:15780"^^xsd:string) "Catalysis of the reaction: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H(2)O = 1-guanidino-1-deoxy-scyllo-inositol + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.47"^^xsd:string) "reductase phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.47"^^xsd:string) Annotation( "MetaCyc:3.1.3.47-RXN"^^xsd:string) "Catalysis of the reaction: H2O + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate = phosphate + [hydroxymethylglutaryl-CoA reductase (NADPH)]."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.47"^^xsd:string) "hydroxymethylglutaryl-CoA reductase (NADPH)-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.47"^^xsd:string) "hydroxymethylglutaryl-CoA reductase (NADPH)-phosphate phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.52"^^xsd:string) "3-methyl-2-oxobutanoate dehydrogenase (lipoamide)-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.52"^^xsd:string) Annotation( "MetaCyc:3.1.3.52-RXN"^^xsd:string) "Catalysis of the reaction: H2O + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] phosphate = phosphate + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.52"^^xsd:string) "3-methyl-2-oxobutanoate dehydrogenase (lipoamide)-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.52"^^xsd:string) "branched-chain oxo-acid dehydrogenase phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.52"^^xsd:string) "branched-chain 2-keto acid dehydrogenase phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.52"^^xsd:string) "branched-chain alpha-keto acid dehydrogenase phosphatase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.54"^^xsd:string) "fructose-2,6-bisphosphate 6-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.54"^^xsd:string) "fructose 2,6-bisphosphate-6-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.54"^^xsd:string) "D-fructose-2,6-bisphosphate 6-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "fructose-2,6-bisphosphate 6-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.54"^^xsd:string) "beta-D-fructose-2,6-bisphosphate 6-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.54"^^xsd:string) Annotation( "RHEA:13336"^^xsd:string) "Catalysis of the reaction: beta-D-fructose 2,6-bisphosphate + H(2)O = beta-D-fructofuranose 2-phosphate + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.13"^^xsd:string) "SEP diesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.13"^^xsd:string) "serine-phosphoethanolamine ethanolaminephosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "serine-ethanolaminephosphate phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.13"^^xsd:string) Annotation( "RHEA:17116"^^xsd:string) "Catalysis of the reaction: H(2)O + serine phosphoethanolamine = H(+) + phosphoethanolamine + serine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.13"^^xsd:string) "serine ethanolamine phosphodiester phosphodiesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.15"^^xsd:string) Annotation( "MetaCyc:3.1.4.15-RXN"^^xsd:string) "Catalysis of the reaction: adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] + H2O = AMP + [L-glutamate:ammonia ligase (ADP-forming)]."^^xsd:string) AnnotationAssertion(rdfs:label "adenylyl-[glutamate-ammonia ligase] hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.15"^^xsd:string) "adenylyl-glutamine-synthetasehydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.15"^^xsd:string) "adenylyl(glutamine synthetase) hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.15"^^xsd:string) "adenylyl-L-glutamate:ammonia ligase (ADP-forming) adenylylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.15"^^xsd:string) "adenylyl-glutamate-ammonia ligase hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycerophosphocholine phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.2"^^xsd:string) Annotation( "MetaCyc:3.1.4.2-RXN"^^xsd:string) "Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = glycerol-3-phosphate + choline."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.2"^^xsd:string) "glycerolphosphorylcholine phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.2"^^xsd:string) "glycerophosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.2"^^xsd:string) "glycerophosphinicocholine diesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.2"^^xsd:string) "sn-glycero-3-phosphocholine glycerophosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.2"^^xsd:string) "sn-glycero-3-phosphorylcholine diesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.2"^^xsd:string) "glycerylphosphorylcholinediesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.38"^^xsd:string) "sn-glycero-3-phosphocholine cholinephosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.38"^^xsd:string) "L-3-glycerylphosphinicocholine cholinephosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycerophosphocholine cholinephosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.38"^^xsd:string) Annotation( "RHEA:19548"^^xsd:string) "Catalysis of the reaction: sn-glycero-3-phosphocholine + H(2)O = choline phosphate + glycerol + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.39"^^xsd:string) Annotation( "MetaCyc:3.1.4.39-RXN"^^xsd:string) "Catalysis of the reaction: H2O + 1-alkyl-sn-glycero-3-phosphoethanolamine = ethanolamine + 1-alkyl-sn-glycerol 3-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "alkylglycerophosphoethanolamine phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.39"^^xsd:string) "lysophospholipase D activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.39"^^xsd:string) "1-alkyl-sn-glycero-3-phosphoethanolamine ethanolaminehydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.40"^^xsd:string) "CMP-N-acylneuraminic acid hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.40"^^xsd:string) "CMP-sialic acid hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.40"^^xsd:string) "cytidine monophosphosialate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.40"^^xsd:string) "CMP-N-acetylneuraminate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.40"^^xsd:string) "cytidine monophosphate-N-acetylneuraminic acid hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.40"^^xsd:string) "CMP-N-acylneuraminate N-acylneuraminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.40"^^xsd:string) "cytidine monophosphosialic hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "CMP-N-acylneuraminate phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.40"^^xsd:string) Annotation( "MetaCyc:3.1.4.40-RXN"^^xsd:string) "Catalysis of the reaction: H2O + CMP-N-acylneuraminate = N-acylneuraminate + CMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.40"^^xsd:string) "CMP-sialate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.42"^^xsd:string) Annotation( "RHEA:16496"^^xsd:string) "Catalysis of the reaction: glycerol 1,2-cyclic phosphate + H(2)O = glycerol 1-phosphate + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "glycerol-1,2-cyclic-phosphate 2-phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.42"^^xsd:string) "rac-glycerol-1,2-cyclic-phosphate 2-glycerophosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.42"^^xsd:string) "rac-glycerol 1:2-cyclic phosphate 2-phosphodiesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.43"^^xsd:string) "1-(sn-glycero-3-phospho)-1D-myo-inositol inositolphosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.43"^^xsd:string) "1-D-myo-inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.43"^^xsd:string) "D-myo-inositol 1,2-cyclic phosphate 2-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.43"^^xsd:string) "D-myo-inositol 1:2-cyclic phosphate 2-phosphohydrolase activity"^^xsd:string) AnnotationAssertion( "1,2-cyclic-inositol-phosphate phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.43"^^xsd:string) Annotation( "MetaCyc:3.1.4.43-RXN"^^xsd:string) "Catalysis of the reaction: H2O + 1-(sn-glycero-3-phospho)-1D-myoinositol = 1D-myo-inositol 1-phosphate + glycerol."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.43"^^xsd:string) "D-inositol 1,2-cyclic phosphate 2-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.43"^^xsd:string) "inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycerophosphoinositol inositolphosphodiesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.44"^^xsd:string) Annotation( "RHEA:16504"^^xsd:string) "Catalysis of the reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H(2)O = sn-glycerol 3-phosphate + myo-inositol + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.44"^^xsd:string) "1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.44"^^xsd:string) "sn-glycero-3-phospho-1-inositol glycerophosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycerophosphoinositol glycerophosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.44"^^xsd:string) "sn-glycero(3)phosphoinositol glycerophosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycosylphosphatidylinositol diacylglycerol-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.14"^^xsd:string) "glycosylphosphatidylinositol-specific phospholipase C activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.14"^^xsd:string) Annotation( "MetaCyc:3.1.4.47-RXN"^^xsd:string) "Catalysis of the reaction: 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol = 1,2-diacyl-sn-glycerol + 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.14"^^xsd:string) "VSG-lipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.14"^^xsd:string) "glycosyl inositol phospholipid anchor-hydrolyzing enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.14"^^xsd:string) "GPI-PLC activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.14"^^xsd:string) "(glycosyl)phosphatidylinositol-specific phospholipase C activity"^^xsd:string) AnnotationAssertion( "variant-surface-glycoprotein phospholipase C activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.14"^^xsd:string) "glycosylphosphatidylinositol-phospholipase C activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.14"^^xsd:string) "6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol diacyl-sn-glycerol-lyase [6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate-forming]"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.14"^^xsd:string) "GPI-specific phospholipase C activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.14"^^xsd:string) "6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.48"^^xsd:string) Annotation( "MetaCyc:3.1.4.48-RXN"^^xsd:string) "Catalysis of the reaction: dolichyl beta-D-glucosyl phosphate + H2O = dolichol-phosphate + beta-D-glucose."^^xsd:string) AnnotationAssertion(rdfs:label "dolichylphosphate-glucose phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.48"^^xsd:string) "Dol-P-Glc phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.48"^^xsd:string) "dolichol phosphoglucose phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.48"^^xsd:string) "dolichyl-beta-D-glucosyl-phosphate dolichylphosphohydrolase activity"^^xsd:string) AnnotationAssertion( "dolichyl-phosphate-glucose phosphodiesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dolichylphosphate-mannose phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.49"^^xsd:string) Annotation( "MetaCyc:3.1.4.49-RXN"^^xsd:string) "Catalysis of the reaction: dolichyl beta-D-mannosyl phosphate + H2O = dolichol-phosphate + mannose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.49"^^xsd:string) "dolichyl-beta-D-mannosyl-phosphate dolichylphosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.49"^^xsd:string) "mannosylphosphodolichol phosphodiesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.51"^^xsd:string) "6-(D-glucose-1-phospho)-D-mannosylglycoprotein glucose-1-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.51"^^xsd:string) Annotation( "MetaCyc:3.1.4.51-RXN"^^xsd:string) "Catalysis of the reaction: H2O + 6-(D-glucose-1-phospho)-D-mannosylglycoprotein = D-mannosylglycoprotein + D-glucose-alpha-1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.51"^^xsd:string) "alpha-glucose-1-phosphate phosphodiesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.11.1.2"^^xsd:string) Annotation( "RHEA:16752"^^xsd:string) "Catalysis of the reaction: H(2)O + phosphonoacetate = acetate + H(+) + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "phosphonoacetate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.11.1.2"^^xsd:string) "phosphonoacetate phosphonohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.12.1.1"^^xsd:string) "trithionate thiosulfohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trithionate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.12.1.1"^^xsd:string) Annotation( "RHEA:21887"^^xsd:string) "Catalysis of the reaction: H(2)O + trithionate = H(+) + sulfate + thiosulfate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.107"^^xsd:string) Annotation( "MetaCyc:3.2.1.107-RXN"^^xsd:string) "Catalysis of the reaction: H2O + protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine = protein beta-D-galactosyl-L-hydroxylysine + beta-D-glucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.107"^^xsd:string) "protein-alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.107"^^xsd:string) "2-O-alpha-D-glucopyranosyl-5-O-alpha-D-galactopyranosylhydroxy-L-lysine glucohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-glucosylgalactosylhydroxylysine glucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.140"^^xsd:string) "oligosaccharide lacto-N-biosylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.140"^^xsd:string) Annotation( "MetaCyc:3.2.1.140-RXN"^^xsd:string) "Catalysis of the reaction: H2O + beta-D-Gal-(1,3)-beta-D-GlcNAc-(1,3)-beta-D-Gal-(1,4)-D-Glc = beta-D-Gal-(1,4)-D-Glc + beta-D-Gal-(1,3)-D-GlcNAc."^^xsd:string) AnnotationAssertion(rdfs:label "lacto-N-biosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.56"^^xsd:string) "3-D-glucuronsyl-N2,6-disulfo-beta-D-glucosamine glucuronohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucuronosyl-disulfoglucosamine glucuronidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.56"^^xsd:string) Annotation( "MetaCyc:3.2.1.56-RXN"^^xsd:string) "Catalysis of the reaction: H2O + 3-D-glucuronosyl-N2-,6-disulfo-beta-D-glucosamine = glucuronate + N2,6-disulfo-D-glucosamine."^^xsd:string) AnnotationAssertion( "glucuronosyl-disulphoglucosamine glucuronidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.56"^^xsd:string) "3-D-glucuronsyl-2-N,6-disulfo-beta-D-glucosamine glucuronohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.10"^^xsd:string) "Pyr5N activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.10"^^xsd:string) "pyrimidine nucleotide N-ribosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.10"^^xsd:string) Annotation( "MetaCyc:3.2.2.10-RXN"^^xsd:string) "Catalysis of the reaction: H2O + a pyrimidine 5'-nucleotide = ribose-5-phosphate + a pyrimidine."^^xsd:string) AnnotationAssertion(rdfs:label "pyrimidine-5'-nucleotide nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.10"^^xsd:string) "pyrimidine-5'-nucleotide phosphoribo(deoxyribo)hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-aspartyl-N-acetylglucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.11"^^xsd:string) "1-beta-aspartyl-N-acetyl-D-glucosaminylamine L-asparaginohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.11"^^xsd:string) Annotation( "RHEA:12327"^^xsd:string) "Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H(2)O = N-acetyl-D-glucosamine + L-asparagine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.11"^^xsd:string) "beta-aspartylacetylglucosaminidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.24"^^xsd:string) "dinitrogenase reductase activating glycohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.24"^^xsd:string) "azoferredoxin glycosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.24"^^xsd:string) Annotation( "MetaCyc:3.2.2.24-RXN"^^xsd:string) "Catalysis of the reaction: ADP-ribosyl-[dinitrogen reductase] = adenosine diphosphate ribose + [dinitrogen reductase]."^^xsd:string) AnnotationAssertion(rdfs:label "ADP-ribosyl-[dinitrogen reductase] hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.24"^^xsd:string) "ADP-ribosyl glycohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.24"^^xsd:string) "ADP-ribosyl-dinitrogen reductase hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.24"^^xsd:string) "ADP-D-ribosyl-dinitrogen reductase ADP-ribosylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.24"^^xsd:string) "dinitrogenase reductase-activating glycohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.24"^^xsd:string) "azoferredoxin-activating enzymes"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.3.2.2"^^xsd:string) Annotation( "MetaCyc:3.3.2.2-RXN"^^xsd:string) "Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphocholine = L-1-glycero-3-phosphocholine + an aldehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.2"^^xsd:string) "1-(1-alkenyl)-sn-glycero-3-phosphocholine aldehydohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alkenylglycerophosphocholine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.2"^^xsd:string) "lysoplasmalogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.3.2.5"^^xsd:string) Annotation( "MetaCyc:3.3.2.5-RXN"^^xsd:string) "Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine = sn-glycero-3-phosphoethanolamine + an aldehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.5"^^xsd:string) "1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine aldehydohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alkenylglycerophosphoethanolamine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-formylmethionylaminoacyl-tRNA deformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.27"^^xsd:string) "N-formyl-L-methionylaminoacyl-tRNA amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.27"^^xsd:string) Annotation( "MetaCyc:3.5.1.27-RXN"^^xsd:string) "Catalysis of the reaction: H2O + charged-fMet-tRNAs = L-methionylaminoacyl-tRNA + formate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.29"^^xsd:string) "2-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.29"^^xsd:string) "alpha-(N-acetylaminomethylene)succinic acid hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.29"^^xsd:string) Annotation( "MetaCyc:3.5.1.29-RXN"^^xsd:string) "Catalysis of the reaction: 2 H2O + 2-(acetamidomethylene)succinate = CO2 + NH3 + succinate semialdehyde + acetate."^^xsd:string) AnnotationAssertion(rdfs:label "2-(acetamidomethylene)succinate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "N-(long-chain-acyl)ethanolamine amidohydrolase activity"^^xsd:string) AnnotationAssertion( "N-acylethanolamine amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-(long-chain-acyl)ethanolamine deacylase activity"^^xsd:string) AnnotationAssertion( "acylethanolamine amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.60"^^xsd:string) Annotation( "MetaCyc:3.5.1.60-RXN"^^xsd:string) "Catalysis of the reaction: H2O + N-(long-chain-acyl)ethanolamine = ethanolamine + a fatty acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.64"^^xsd:string) "nalpha-benzyloxycarbonylleucine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.64"^^xsd:string) "nalpha-benzyloxycarbonyl amino acid urethane hydrolase IV"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.64"^^xsd:string) Annotation( "RHEA:18904"^^xsd:string) "Catalysis of the reaction: N-benzyloxycarbonyl-L-leucine + H(2)O + H(+) = L-leucine + benzyl alcohol + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.64"^^xsd:string) "alpha-N-benzyloxycarbonyl-L-leucine urethanehydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.64"^^xsd:string) "benzyloxycarbonylleucine hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N(alpha)-benzyloxycarbonylleucine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.64"^^xsd:string) "nalpha-benzyloxycarbonyl-L-leucine urethanehydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.66"^^xsd:string) Annotation( "RHEA:17680"^^xsd:string) "Catalysis of the reaction: (2Z)-2-(acetamidomethylene)-3-(hydroxymethyl)succinate + 2 H(2)O + H(+) = 2-(hydroxymethyl)-4-oxobutanoate + acetate + CO(2) + NH(4)(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.66"^^xsd:string) "2-(hydroxymethyl)-3-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.66"^^xsd:string) "compound B hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.66"^^xsd:string) "alpha-hydroxymethyl-alpha'-(N-acetylaminomethylene)succinic acid hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.72"^^xsd:string) "benzoyl-D-arginine arylamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.72"^^xsd:string) "D-BAPA-ase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-benzoylarginine-4-nitroanilide amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.72"^^xsd:string) Annotation( "RHEA:14424"^^xsd:string) "Catalysis of the reaction: N(2)-benzoyl-D-arginine-4-nitroanilide + H(2)O = 4-nitroaniline + N(2)-benzoyl-D-arginine + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.72"^^xsd:string) "N-benzoyl-D-arginine-4-nitroanilide amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arylalkyl acylamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.76"^^xsd:string) "N-acetylarylalkylamine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.76"^^xsd:string) "aralkyl acylamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.76"^^xsd:string) Annotation( "MetaCyc:3.5.1.76-RXN"^^xsd:string) "Catalysis of the reaction: H2O + N-acetylarylalkylamine = acetate + arylalkylamine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-carbamoyl-D-amino acid hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.77"^^xsd:string) Annotation( "MetaCyc:3.5.1.77-RXN"^^xsd:string) "Catalysis of the reaction: H2O + N-carbamoyl-D-amino acid = CO2 + NH3 + D-amino acid."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.77"^^xsd:string) "N-carbamoyl-D-amino acid amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phthalyl amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.79"^^xsd:string) "o-phthalyl amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.79"^^xsd:string) "phthalyl-amide amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.79"^^xsd:string) Annotation( "MetaCyc:3.5.1.79-RXN"^^xsd:string) "Catalysis of the reaction: H2O + a phthalylamide = phthalate + substituted amine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-acetylgalactosamine-6-phosphate deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.-"^^xsd:string) Annotation( "MetaCyc:3.5.1.80-RXN"^^xsd:string) "Catalysis of the reaction: H2O + N-acetyl-D-galactosamine 6-phosphate = acetate + D-galactosamine 6-phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.81"^^xsd:string) "D-aminoacylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acyl-D-amino-acid deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.81"^^xsd:string) "N-acyl-D-amino acid amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.81"^^xsd:string) Annotation( "MetaCyc:3.5.1.81-RXN"^^xsd:string) "Catalysis of the reaction: H2O + N-acyl-D-amino acid = D-amino acid + an acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.82"^^xsd:string) Annotation( "RHEA:12836"^^xsd:string) "Catalysis of the reaction: N-acyl-D-glutamate + H(2)O = D-glutamate + a carboxylate."^^xsd:string) AnnotationAssertion(rdfs:label "N-acyl-D-glutamate deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.82"^^xsd:string) "N-acyl-D-glutamate amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.83"^^xsd:string) "N-acyl-D-aspartate amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.83"^^xsd:string) Annotation( "RHEA:18288"^^xsd:string) "Catalysis of the reaction: N-acyl-D-aspartate + H(2)O = D-aspartate + a carboxylate."^^xsd:string) AnnotationAssertion(rdfs:label "N-acyl-D-aspartate deacylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.2.14"^^xsd:string) "N-methylhydantoinase (ATP-hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.14"^^xsd:string) "N-methylhydantoin amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.14"^^xsd:string) "N-methylhydantoinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.14"^^xsd:string) "N-methylimidazolidine-2,4-dione amidohydrolase (ATP-hydrolysing)"^^xsd:string) AnnotationAssertion(rdfs:label "N-methylhydantoinase (ATP-hydrolyzing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.14"^^xsd:string) "N-methylhydantoin hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.14"^^xsd:string) Annotation( "RHEA:11723"^^xsd:string) "Catalysis of the reaction: N-methylhydantoin + ATP + 2 H(2)O = N-carbamoylsarcosine + ADP + 3 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.14"^^xsd:string) "methylhydantoin amidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methylenediurea deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.21"^^xsd:string) "methylenediurease activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.21"^^xsd:string) Annotation( "MetaCyc:3.5.3.21-RXN"^^xsd:string) "Catalysis of the reaction: 2 H2O + methylenediurea = CO2 + 2 NH3 + N-hydroxymethylurea."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.21"^^xsd:string) "methylenediurea aminohydrolase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1-pyrroline-4-hydroxy-2-carboxylate deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.22"^^xsd:string) "1-pyrroline-4-hydroxy-2-carboxylate aminohydrolase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.22"^^xsd:string) "HPC deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.22"^^xsd:string) Annotation( "RHEA:10563"^^xsd:string) "Catalysis of the reaction: 4-hydroxy-1-pyrroline-2-carboxylate + H(2)O + H(+) = 2,5-dioxopentanoate + NH(4)(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ricinine nitrilase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.5.2"^^xsd:string) Annotation( "MetaCyc:3.5.5.2-RXN"^^xsd:string) "Catalysis of the reaction: H2O + ricinine = NH3 + 3-carboxy-4-methoxy-N-methyl-2-pyridone."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.5.2"^^xsd:string) "ricinine aminohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.5.4"^^xsd:string) "beta-cyanoalanine nitrilase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyanoalanine nitrilase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.5.4"^^xsd:string) "3-cyano-L-alanine aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.5.4"^^xsd:string) Annotation( "RHEA:25310"^^xsd:string) "Catalysis of the reaction: 3-cyano-L-alanine + 2 H(2)O + H(+) = L-aspartate + NH(4)(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.5.5"^^xsd:string) "arylacetonitrile aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.5.5"^^xsd:string) Annotation( "MetaCyc:3.5.5.5-RXN"^^xsd:string) "Catalysis of the reaction: 2 H2O + 4-chlorophenylacetonitrile = 4-chlorophenylacetate + NH3."^^xsd:string) AnnotationAssertion(rdfs:label "arylacetonitrilase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "nucleoside-triphosphate pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.19"^^xsd:string) "nucleoside-triphosphate diphosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.19"^^xsd:string) Annotation( "MetaCyc:3.6.1.19-RXN"^^xsd:string) "Catalysis of the reaction: H2O + a nucleoside triphosphate = diphosphate + a nucleotide."^^xsd:string) AnnotationAssertion(rdfs:label "nucleoside-triphosphate diphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "oligosaccharide-diphosphodolichol pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.44"^^xsd:string) "oligosaccharide-diphosphodolichol phosphodolichohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.44"^^xsd:string) Annotation( "MetaCyc:3.6.1.44-RXN"^^xsd:string) "Catalysis of the reaction: H2O + oligosaccharide-diphosphodolichol = dolichol-phosphate + oligosaccharide phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "oligosaccharide-diphosphodolichol diphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.51"^^xsd:string) "3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxy-lyase (3-hydroxy-2-methylpyridine-5-carboxylate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.51"^^xsd:string) Annotation( "RHEA:13672"^^xsd:string) "Catalysis of the reaction: 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + H(+) = 5-hydroxy-6-methylpyridine-3-carboxylate + CO(2)."^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.51"^^xsd:string) "3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxy-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.64"^^xsd:string) "2,2-dialkyl-2-amino acid-pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.64"^^xsd:string) "dialkylamino-acid decarboxylase (pyruvate)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.64"^^xsd:string) "2,2-dialkylglycine carboxy-lyase (amino-transferring; L-alanine-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "2,2-dialkylglycine decarboxylase (pyruvate) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.64"^^xsd:string) "L-alanine-alpha-ketobutyrate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.64"^^xsd:string) "2,2-dialkylglycine carboxy-lyase (amino-transferring)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.64"^^xsd:string) Annotation( "RHEA:16076"^^xsd:string) "Catalysis of the reaction: 2,2-dialkylglycine + H(+) + pyruvate = L-alanine + CO(2) + dialkyl ketone."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.64"^^xsd:string) "alpha-dialkyl amino acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.64"^^xsd:string) "dialkyl amino acid (pyruvate) decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.72"^^xsd:string) "BCKA"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.72"^^xsd:string) Annotation( "RHEA:21111"^^xsd:string) "Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + H(+) = 2-methylbutanal + CO(2)."^^xsd:string) AnnotationAssertion(rdfs:label "branched-chain-2-oxoacid decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.72"^^xsd:string) "(3S)-3-methyl-2-oxopentanoate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.72"^^xsd:string) "branched-chain oxo acid decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.72"^^xsd:string) "(3S)-3-methyl-2-oxopentanoate carboxy-lyase (2-methylbutanal-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.72"^^xsd:string) "branched-chain alpha-keto acid decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.72"^^xsd:string) "branched-chain keto acid decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.74"^^xsd:string) Annotation( "MetaCyc:4.1.1.74-RXN"^^xsd:string) "Catalysis of the reaction: indolepyruvate = CO2 + indole acetaldehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.74"^^xsd:string) "3-(indol-3-yl)pyruvate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.74"^^xsd:string) "indole-3-pyruvate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.74"^^xsd:string) "3-(indol-3-yl)pyruvate carboxy-lyase [(2-indol-3-yl)acetaldehyde-forming]"^^xsd:string) AnnotationAssertion(rdfs:label "indolepyruvate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.74"^^xsd:string) "indol-3-yl-pyruvate carboxy-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.75"^^xsd:string) Annotation( "RHEA:11343"^^xsd:string) "Catalysis of the reaction: 5-guanidino-2-oxopentanoate + H(+) = 4-guanidinobutanal + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.75"^^xsd:string) "2-oxo-5-guanidinovalerate alpha-ketoarginine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.75"^^xsd:string) "alpha-ketoarginine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.75"^^xsd:string) "2-oxo-5-guanidinopentanoate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.75"^^xsd:string) "2-oxo-5-guanidinopentanoate carboxy-lyase (4-guanidinobutanal-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "5-guanidino-2-oxopentanoate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.75"^^xsd:string) "2-oxo-5-guanidinopentanoate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.76"^^xsd:string) "2-aryl-2-methylmalonate carboxy-lyase (2-arylpropanoate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.76"^^xsd:string) "AMDase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.76"^^xsd:string) "AMDASE"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.76"^^xsd:string) "2-aryl-2-methylmalonate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arylmalonate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.76"^^xsd:string) Annotation( "RHEA:20516"^^xsd:string) "Catalysis of the reaction: 2-aryl-2-methylmalonate + H(+) = 2-arylpropionate + CO(2)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.77"^^xsd:string) "4-oxalocrotonate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-oxalocrotonate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.77"^^xsd:string) Annotation( "MetaCyc:4.1.1.77-RXN"^^xsd:string) "Catalysis of the reaction: 4-oxalocrotonate = CO2 + 2-oxopent-4-enoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.77"^^xsd:string) "4-oxalocrotonate carboxy-lyase (2-oxopent-4-enoate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.18"^^xsd:string) "3-deoxy-D-pentulosonic acid aldolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.18"^^xsd:string) Annotation( "MetaCyc:4.1.2.18-RXN"^^xsd:string) "Catalysis of the reaction: 2-dehydro-3-deoxy-L-pentonate = glycolaldehyde + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.18"^^xsd:string) "2-keto-3-deoxy-D-xylonate aldolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-dehydro-3-deoxy-L-pentonate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.18"^^xsd:string) "2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.18"^^xsd:string) "2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase (pyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.18"^^xsd:string) "2-keto-3-deoxy-L-arabonate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.18"^^xsd:string) "2-keto-3-deoxy-L-pentonate aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.23"^^xsd:string) "KDOaldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.23"^^xsd:string) "2-keto-3-deoxyoctonate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.23"^^xsd:string) "3-deoxy-D-manno-octulosonate D-arabinose-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.23"^^xsd:string) Annotation( "RHEA:23343"^^xsd:string) "Catalysis of the reaction: 3-deoxy-D-manno-octulosonate = D-arabinose + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.23"^^xsd:string) "3-deoxy-D-manno-octulosonate D-arabinose-lyase (pyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.23"^^xsd:string) "3-deoxyoctulosonic aldolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-deoxy-D-manno-octulosonate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.23"^^xsd:string) "3-deoxy-D-manno-octulosonic aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.23"^^xsd:string) "2-keto-3-deoxyoctonic aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.28"^^xsd:string) "2-keto-3-deoxy-D-pentonate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.28"^^xsd:string) "2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-dehydro-3-deoxy-D-pentonate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.28"^^xsd:string) "3-deoxy-D-pentulosonic acid aldolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.28"^^xsd:string) Annotation( "RHEA:20612"^^xsd:string) "Catalysis of the reaction: 2-dehydro-3-deoxy-D-arabinonate = glycolaldehyde + pyruvate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.29"^^xsd:string) "5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase (pyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.29"^^xsd:string) Annotation( "RHEA:13180"^^xsd:string) "Catalysis of the reaction: 6-phospho-5-dehydro-2-deoxy-D-gluconate = 3-oxopropanoate + glycerone phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.29"^^xsd:string) "phospho-5-dehydro-2-deoxygluconate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.29"^^xsd:string) "5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.29"^^xsd:string) "phospho-5-keto-2-deoxygluconate aldolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "5-dehydro-2-deoxyphosphogluconate aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.30"^^xsd:string) "17alpha-hydroxyprogesterone aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.30"^^xsd:string) "17alpha-hydroxyprogesterone acetaldehyde-lyase (4-androstene-3,17-dione-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.30"^^xsd:string) "C-17/C-20 lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "17-alpha-hydroxyprogesterone aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.30"^^xsd:string) "17-alpha-hydroxyprogesterone acetaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.30"^^xsd:string) Annotation( "MetaCyc:4.1.2.30-RXN"^^xsd:string) "Catalysis of the reaction: 17-alpha-hydroxyprogesterone = acetaldehyde + 4-androstene-3,17-dione."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.30"^^xsd:string) "17alpha-hydroxyprogesterone acetaldehyde-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-hydroxy-4-methyl-2-oxoglutarate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.17"^^xsd:string) "4-hydroxy-4-methyl-2-ketoglutarate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.17"^^xsd:string) "4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase (pyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.17"^^xsd:string) Annotation( "MetaCyc:4.1.3.17-RXN"^^xsd:string) "Catalysis of the reaction: 4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.17"^^xsd:string) "gamma-methyl-gamma-hydroxy-alpha-ketoglutaric aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.17"^^xsd:string) "pyruvate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.17"^^xsd:string) "4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-acylneuraminate-9-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.57"^^xsd:string) "N-acetylneuraminate 9-phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "N-acetylneuraminic acid phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.57"^^xsd:string) "N-acetylneuraminate 9-phosphate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.57"^^xsd:string) "N-acylneuraminate-9-phosphate pyruvate-lyase (pyruvate-phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.57"^^xsd:string) "N-acetylneuraminate 9-phosphate sialic acid 9-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.57"^^xsd:string) "phosphoenolpyruvate:N-acyl-D-mannosamine-6-phosphate 1-(2-carboxy-2-oxoethyl)transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.57"^^xsd:string) "sialic acid 9-phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.57"^^xsd:string) Annotation( "MetaCyc:4.1.3.20-RXN"^^xsd:string) "Catalysis of the reaction: H2O + phosphoenolpyruvate + N-acyl-D-mannosamine 6-phosphate = phosphate + N-acylneuraminate 9-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3.26"^^xsd:string) "3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase (7-methyl-3-oxooct-6-enoyl-CoA-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.26"^^xsd:string) "3-hydroxy-3-isohexenylglutaryl coenzyme A lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxy-3-isohexenylglutaryl-CoA lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.26"^^xsd:string) "3-hydroxy-3-isohexenylglutaryl-CoA isopentenylacetoacetyl-CoA-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.26"^^xsd:string) "beta-hydroxy-beta-isohexenylglutaryl CoA-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.26"^^xsd:string) Annotation( "RHEA:23087"^^xsd:string) "Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA + 4 H(+) = 7-methyl-3-oxooct-6-enoyl-CoA + acetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.26"^^xsd:string) "hydroxyisohexenylglutaryl-CoA:acetatelyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.26"^^xsd:string) "3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3.35"^^xsd:string) "(1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.35"^^xsd:string) "(1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase (acetyl-CoA-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "(1-hydroxycyclohexan-1-yl)acetyl-CoA lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.35"^^xsd:string) Annotation( "RHEA:23871"^^xsd:string) "Catalysis of the reaction: (1-hydroxycyclohexan-1-yl)acetyl-CoA = acetyl-CoA + cyclohexanone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.1.20"^^xsd:string) Annotation( "MetaCyc:4.3.1.20-RXN"^^xsd:string) "Catalysis of the reaction: erythro-3-hydroxy-L-aspartate = NH3 + oxaloacetic acid."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.20"^^xsd:string) "erythro-3-hydroxy-Ls-aspartate ammonia-lyase (oxaloacetate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.20"^^xsd:string) "erythro-3-hydroxy-Ls-aspartate hydro-lyase (deaminating)"^^xsd:string) AnnotationAssertion( "erythro-3-hydroxyaspartate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.20"^^xsd:string) "erythro-beta-hydroxyaspartate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.20"^^xsd:string) "erythro-3-hydroxy-Ls-aspartate ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.20"^^xsd:string) "3-hydroxyaspartate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.20"^^xsd:string) "erythro-3-hydroxy-L(s)-aspartate hydro-lyase (deaminating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "erythro-3-hydroxyaspartate ammonia-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5-dehydro-4-deoxyglucarate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.41"^^xsd:string) Annotation( "RHEA:24611"^^xsd:string) "Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucarate + H(+) = 2,5-dioxopentanoate + CO(2) + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.41"^^xsd:string) "5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating; 2,5-dioxopentanoate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.41"^^xsd:string) "5-keto-4-deoxy-glucarate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.41"^^xsd:string) "D-4-deoxy-5-ketoglucarate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.41"^^xsd:string) "deoxyketoglucarate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.41"^^xsd:string) "5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.43"^^xsd:string) Annotation( "RHEA:17204"^^xsd:string) "Catalysis of the reaction: 2-dehydro-3-deoxy-L-arabinonate = 2,5-dioxopentanoate + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.43"^^xsd:string) "2-keto-3-deoxy-L-arabinonate dehydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-dehydro-3-deoxy-L-arabinonate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.43"^^xsd:string) "2-dehydro-3-deoxy-L-arabinonate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.43"^^xsd:string) "2-dehydro-3-deoxy-L-arabinonate hydro-lyase (2,5-dioxopentanoate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.58"^^xsd:string) "beta-hydroxybutyryl acyl carrier protein (ACP) dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.58"^^xsd:string) "(3R)-3-hydroxybutanoyl-acyl-carrier-protein hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.58"^^xsd:string) "3-hydroxybutyryl acyl carrier protein dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.58"^^xsd:string) "crotonyl acyl carrier protein hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.58"^^xsd:string) "crotonoyl-acyl-carrier-protein hydratase activity"^^xsd:string) AnnotationAssertion( "crotonoyl-ACP hydratase activity"^^xsd:string) AnnotationAssertion( "crotonoyl-[acyl-carrier protein] hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.58"^^xsd:string) "enoyl acyl carrier protein hydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.58"^^xsd:string) "(3R)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.58"^^xsd:string) "beta-hydroxybutyryl acyl carrier protein dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.58"^^xsd:string) Annotation( "MetaCyc:4.2.1.58-RXN"^^xsd:string) "Catalysis of the reaction: (3R)-3-hydroxybutanoyl-[acyl-carrier protein] = H2O + but-2-enoyl-[acyl-carrier protein]."^^xsd:string) AnnotationAssertion(rdfs:label "crotonoyl-[acyl-carrier-protein] hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.58"^^xsd:string) "(3R)-3-hydroxybutanoyl-acyl-carrier-protein hydro-lyase (but-2-enoyl-acyl-carrier protein-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3-hydroxyoctanoyl-ACP dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.59"^^xsd:string) Annotation( "MetaCyc:4.2.1.59-RXN"^^xsd:string) "Catalysis of the reaction: (3R)-3-hydroxyoctanoyl-[acyl-carrier protein] = H2O + 2-octenoyl-[acyl-carrier protein]."^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity"^^xsd:string) AnnotationAssertion( "3-hydroxyoctanoyl-[acyl-carrier protein] dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.59"^^xsd:string) "(3R)-3-hydroxyoctanoyl-acyl-carrier-protein hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.59"^^xsd:string) "D-3-hydroxyoctanoyl-[acyl carrier protein] dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.59"^^xsd:string) "D-3-hydroxyoctanoyl-acyl carrier protein dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.59"^^xsd:string) "(3R)-3-hydroxyoctanoyl-acyl-carrier-protein hydro-lyase (oct-2-enoyl-acyl-carrier protein-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.59"^^xsd:string) "beta-hydroxyoctanoyl-ACP-dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.59"^^xsd:string) "beta-hydroxyoctanoyl-acyl carrier protein dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.59"^^xsd:string) "beta-hydroxyoctanoyl thioester dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.59"^^xsd:string) "3-hydroxyoctanoyl-acyl-carrier-protein dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.59"^^xsd:string) "(3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protoaphin-aglucone dehydratase (cyclizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.73"^^xsd:string) "protoaphin dehydratase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.73"^^xsd:string) "protoaphin dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.73"^^xsd:string) "protoaphin-aglucone hydro-lyase (cyclizing; xanthoaphin-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.73"^^xsd:string) "protoaphin-aglucone hydro-lyase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.73"^^xsd:string) Annotation( "RHEA:23879"^^xsd:string) "Catalysis of the reaction: protoaphin aglucone = H(2)O + xanthoaphin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.93"^^xsd:string) "reduced nicotinamide adenine dinucleotide hydrate dehydratase activity"^^xsd:string) AnnotationAssertion( "ATP-dependent H4NAD(P)OH dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.93"^^xsd:string) Annotation( "RHEA:19020"^^xsd:string) "Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ATP = ADP + 3 H(+) + NADH + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "ATP-dependent NAD(P)H-hydrate dehydratase activity"^^xsd:string) AnnotationAssertion( "ATP-dependent H(4)NAD(P)OH dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.93"^^xsd:string) "(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ATP-hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.93"^^xsd:string) "(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase(ATP-hydrolysing; NADH-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.97"^^xsd:string) "phaseollidin-hydrate hydro-lyase (phaseollidin-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "phaseollidin hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.97"^^xsd:string) Annotation( "RHEA:19772"^^xsd:string) "Catalysis of the reaction: phaseollidin hydrate = H(2)O + phaseollidin."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.97"^^xsd:string) "phaseollidin-hydrate hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "16-dehydroprogesterone hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.98"^^xsd:string) "16alpha-hydroxyprogesterone dehydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.98"^^xsd:string) Annotation( "MetaCyc:4.2.1.98-RXN"^^xsd:string) "Catalysis of the reaction: 16-alpha-hydroxyprogesterone = H2O + 16-dehydroprogesterone."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.98"^^xsd:string) "16alpha-hydroxyprogesterone hydro-lyase (16,17-didehydroprogesterone-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.98"^^xsd:string) "16alpha-hydroxyprogesterone dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.98"^^xsd:string) "16alpha-hydroxyprogesterone hydro-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "16-alpha-hydroxyprogesterone dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.98"^^xsd:string) "16-alpha-dehydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.98"^^xsd:string) "16-alpha-hydroxyprogesterone dehydroxylase activity"^^xsd:string) AnnotationAssertion( "hydroxyprogesterone dehydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.98"^^xsd:string) "16alpha-dehydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-methylisocitrate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.99"^^xsd:string) "(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.99"^^xsd:string) Annotation( "RHEA:17944"^^xsd:string) "Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = cis-2-methylaconitate + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.99"^^xsd:string) "(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming]"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.2.13"^^xsd:string) "alpha-1,4-glucan 1,5-anhydro-D-fructose eliminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.13"^^xsd:string) Annotation( "MetaCyc:4.2.2.13-RXN"^^xsd:string) "Catalysis of the reaction: linear alpha-D-glucan = 1,5-anhydro-D-fructose + beta-D-glucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.13"^^xsd:string) "exo-(1->4)-alpha-D-glucan lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.13"^^xsd:string) "alpha-1,4-glucan exo-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.13"^^xsd:string) "alpha-1,4-glucan lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "exo-(1,4)-alpha-D-glucan lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.13"^^xsd:string) "alpha-(1->4)-glucan 1,5-anhydro-D-fructose eliminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.13"^^xsd:string) "exo-alpha-1,4-glucan lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.13"^^xsd:string) "(1->4)-alpha-D-glucan exo-4-lyase (1,5-anhydro-D-fructose-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.51"^^xsd:string) "beta-(1-pyrazolyl)alanine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.51"^^xsd:string) "3-O-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.51"^^xsd:string) "beta-pyrazolealanine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.51"^^xsd:string) "BPA-synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.51"^^xsd:string) "O(3)-acetyl-L-serine acetate-lyase (adding pyrazole) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.51"^^xsd:string) "pyrazolylalaninase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.51"^^xsd:string) "O3-acetyl-L-serine acetate-lyase (adding pyrazole)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.51"^^xsd:string) "O3-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.51"^^xsd:string) "pyrazolealanine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.51"^^xsd:string) Annotation( "RHEA:13120"^^xsd:string) "Catalysis of the reaction: O-acetyl-L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + acetate + H(+)."^^xsd:string) AnnotationAssertion( "beta-pyrazolylalanine synthase (acetylserine) activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-pyrazolylalanine synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.1.14"^^xsd:string) "L-3-aminobutyryl-CoA ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.14"^^xsd:string) "L-3-aminobutyryl-CoA ammonia-lyase (crotonoyl-CoA-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.14"^^xsd:string) Annotation( "RHEA:10059"^^xsd:string) "Catalysis of the reaction: (S)-3-aminobutanoyl-CoA = crotonoyl-CoA + NH(4)(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.14"^^xsd:string) "L-3-aminobutyryl-CoA deaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-aminobutyryl-CoA ammonia-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.5.1.4"^^xsd:string) "L-2-amino-4-chloro-4-pentenoate dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.5.1.4"^^xsd:string) Annotation( "RHEA:11623"^^xsd:string) "Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate + H(2)O = 2-oxopent-4-enoate + chloride + H(+) + NH(4)(+)."^^xsd:string) AnnotationAssertion(rdfs:label "L-2-amino-4-chloropent-4-enoate dehydrochlorinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.5.1.4"^^xsd:string) "L-2-amino-4-chloropent-4-enoate chloride-lyase (adding H2O; deaminating; 2-oxopent-4-enoate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.5.1.4"^^xsd:string) "L-2-amino-4-chloropent-4-enoate chloride-lyase (deaminating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.13"^^xsd:string) "D-cadinene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.13"^^xsd:string) Annotation( "MetaCyc:4.6.1.11-RXN"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (+)-delta-cadinene."^^xsd:string) AnnotationAssertion(rdfs:label "(+)-delta-cadinene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.13"^^xsd:string) "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-delta-cadinene-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.1.11"^^xsd:string) "phenylalanine racemase (ATP-hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.11"^^xsd:string) Annotation( "RHEA:20204"^^xsd:string) "Catalysis of the reaction: L-phenylalanine + ATP + H(2)O = D-phenylalanine + AMP + diphosphate + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.11"^^xsd:string) "phenylalanine racemase (adenosine triphosphate-hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.11"^^xsd:string) "gramicidin S synthetase I"^^xsd:string) AnnotationAssertion(rdfs:label "phenylalanine racemase (ATP-hydrolyzing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.11"^^xsd:string) "phenylalanine racemase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.1.15"^^xsd:string) "2-amino-hexano-6-lactam racemase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-aminohexano-6-lactam racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.15"^^xsd:string) "alpha-amino-epsilon-caprolactam racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.15"^^xsd:string) Annotation( "RHEA:14816"^^xsd:string) "Catalysis of the reaction: L-2-aminohexano-6-lactam = D-2-aminohexano-6-lactam."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.17"^^xsd:string) Annotation( "MetaCyc:5.1.3.17-RXN"^^xsd:string) "Catalysis of the reaction: heparosan-N-sulfate D-glucuronate = heparosan-N-sulfate L-iduronate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.17"^^xsd:string) "D-glucuronyl C-5 epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.17"^^xsd:string) "polyglucuronate epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.17"^^xsd:string) "heparosan epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.17"^^xsd:string) "poly[(1,4)-beta-D-glucuronosyl-(1,4)-N-sulfo-alpha-D-glucosaminyl] glucurono-5-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.17"^^xsd:string) "C-5 uronosyl epimerase activity"^^xsd:string) AnnotationAssertion( "heparosan-N-sulphate-glucuronate 5-epimerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "heparosan-N-sulfate-glucuronate 5-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.17"^^xsd:string) "heparosan-N-sulfate-D-glucuronosyl 5-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.9"^^xsd:string) "acylmannosamine phosphate 2-epimerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acylglucosamine-6-phosphate 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.9"^^xsd:string) "N-acyl-D-glucosamine-6-phosphate 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.9"^^xsd:string) "N-acetylmannosamine-6-phosphate 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.9"^^xsd:string) "acylglucosamine-6-phosphate 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.9"^^xsd:string) "acylglucosamine phosphate 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.9"^^xsd:string) Annotation( "MetaCyc:5.1.3.9-RXN"^^xsd:string) "Catalysis of the reaction: N-acyl-D-glucosamine 6-phosphate = N-acyl-D-mannosamine 6-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.9"^^xsd:string) "N-acetylglucosmamine 6-phosphate 2-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.2.1.10"^^xsd:string) Annotation( "RHEA:10927"^^xsd:string) "Catalysis of the reaction: cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide = trans-2-chloro-4-carboxymethylenebut-2-en-1,4-olide."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.-"^^xsd:string) "chlorodienelactone isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.10"^^xsd:string) "2-chloro-4-carboxymethylenebut-2-en-1,4-olide cis-trans-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.-"^^xsd:string) "2-chlorocarboxymethylenebutenolide isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-hydroxyphenylacetaldehyde-oxime isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.11"^^xsd:string) Annotation( "MetaCyc:5.2.1.11-RXN"^^xsd:string) "Catalysis of the reaction: (E)-4-hydroxyphenylacetaldehyde oxime = (Z)-4-hydroxyphenylacetaldehyde oxime."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.2.5"^^xsd:string) "glucose-1-phosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.5"^^xsd:string) Annotation( "MetaCyc:5.4.2.5-RXN"^^xsd:string) "Catalysis of the reaction: glucose-1-phosphate = glucose-6-phosphate; using D-glucose as a cofactor."^^xsd:string) AnnotationAssertion(rdfs:label "phosphoglucomutase (glucose-cofactor) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.5"^^xsd:string) "alpha-D-glucose 1,6-phosphomutase (glucose-cofactor)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.99.14"^^xsd:string) "4-carboxymethyl-4-methylbut-2-en-1,4-olide methylmutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.14"^^xsd:string) "4-methyl-2-enelactone methyl-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.14"^^xsd:string) "4-methyl-3-enelactone methyl isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.14"^^xsd:string) Annotation( "RHEA:19240"^^xsd:string) "Catalysis of the reaction: 4-carboxymethyl-4-methylbut-2-en-1,4-olide = 4-carboxymethyl-3-methylbut-2-en-1,4-olide."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.14"^^xsd:string) "4-methylmuconolactone methylisomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-carboxymethyl-4-methylbutenolide mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.14"^^xsd:string) "4-methyl-2-enelactone isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.99.15"^^xsd:string) "maltodextrin alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.15"^^xsd:string) "(1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.15"^^xsd:string) Annotation( "MetaCyc:5.4.99.15-RXN"^^xsd:string) "Catalysis of the reaction: 4-[(1->4)-alpha-D-glucosyl](n-1)-D-glucose = 1-alpha-D-[(1->4)-alpha-D-glucosyl](n-1)-alpha-D-glucopyranoside."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.15"^^xsd:string) "malto-oligosyltrehalose synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.99.16"^^xsd:string) "maltose alpha-D-glucosylmutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.16"^^xsd:string) "trehalose synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "maltose alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.16"^^xsd:string) Annotation( "MetaCyc:5.4.99.16-RXN"^^xsd:string) "Catalysis of the reaction: maltose = trehalose."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.16"^^xsd:string) "maltose glucosylmutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.5.1.2"^^xsd:string) "beta-carboxymuconate lactonizing enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.2"^^xsd:string) "3-carboxymuconolactone hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.2"^^xsd:string) "2-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.2"^^xsd:string) "3-carboxymuconate lactonizing enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.2"^^xsd:string) "CMLE activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-carboxy-cis,cis-muconate cycloisomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.2"^^xsd:string) Annotation( "RHEA:23659"^^xsd:string) "Catalysis of the reaction: 2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate = 3-carboxy-cis,cis-muconate + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.13"^^xsd:string) "D-alanyl-poly(phosphoribitol) synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.13"^^xsd:string) "D-alanine-activating enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-alanine-poly(phosphoribitol) ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.13"^^xsd:string) "D-alanine-D-alanyl carrier protein ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.13"^^xsd:string) "D-alanine: membrane acceptor ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.13"^^xsd:string) "D-alanine-membrane acceptor ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.13"^^xsd:string) Annotation( "MetaCyc:6.1.1.13-RXN"^^xsd:string) "Catalysis of the reaction: poly(ribitol phosphate) + D-alanine + ATP = O-D-alanyl-poly(ribitol phosphate) + diphosphate + AMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.13"^^xsd:string) "D-alanine:poly(phosphoribitol) ligase (AMP-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "long-chain-fatty-acid-luciferin-component ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.19"^^xsd:string) "acyl-protein synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15904"^^xsd:string) Annotation( "EC:6.2.1.19"^^xsd:string) Annotation( "MetaCyc:6.2.1.19-RXN"^^xsd:string) "Catalysis of the reaction: protein + an acid + ATP = an acyl-protein thiolester + diphosphate + AMP. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22."^^xsd:string) AnnotationAssertion(rdfs:label "long-chain fatty acid luciferin component ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "long-chain-fatty-acid luciferin component ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.19"^^xsd:string) "long-chain-fatty-acid:protein ligase (AMP-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.30"^^xsd:string) "phenacyl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.30"^^xsd:string) "phenylacetate:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.30"^^xsd:string) "phenylacetyl-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.30"^^xsd:string) "PA-CoA ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phenylacetate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.30"^^xsd:string) "phenylacetyl-CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.30"^^xsd:string) Annotation( "RHEA:20959"^^xsd:string) "Catalysis of the reaction: ATP + CoA + phenylacetate = AMP + diphosphate + H(+) + phenylacetyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.28"^^xsd:string) "3alpha,7alpha-dihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.28"^^xsd:string) Annotation( "MetaCyc:6.2.1.28-RXN"^^xsd:string) "Catalysis of the reaction: CoA + 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate + ATP = 3-alpha,7-alpha-dihydroxy-5-beta-cholestanoyl-CoA + diphosphate + AMP."^^xsd:string) AnnotationAssertion(rdfs:label "3-alpha,7-alpha-dihydroxy-5-beta-cholestanate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.28"^^xsd:string) "3alpha,7alpha-dihydroxy-5beta-cholestanate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.28"^^xsd:string) "DHCA-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.28"^^xsd:string) "3alpha,7alpha-dihydroxy-5beta-cholestanoyl coenzyme A synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aspartate-ammonia ligase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.4"^^xsd:string) "asparagine synthetase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.4"^^xsd:string) Annotation( "RHEA:14200"^^xsd:string) "Catalysis of the reaction: L-aspartate + ATP + NH(4)(+) = L-asparagine + ADP + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.4"^^xsd:string) "asparagine synthetase (adenosine diphosphate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.4"^^xsd:string) "L-aspartate:ammonia ligase (ADP-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.1.9"^^xsd:string) "TSR synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.9"^^xsd:string) Annotation( "MetaCyc:6.3.1.9-RXN"^^xsd:string) "Catalysis of the reaction: reduced glutathione + glutathionylspermidine + ATP = trypanothione + ADP + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.9"^^xsd:string) "glutathionylspermidine:glutathione ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "trypanothione synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.10"^^xsd:string) "UDP-N-acetylmuramoylalanyl-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.10"^^xsd:string) "UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.10"^^xsd:string) "UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.10"^^xsd:string) Annotation( "MetaCyc:6.3.2.10-RXN"^^xsd:string) "Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.10"^^xsd:string) "UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.10"^^xsd:string) "UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine:D-alanyl-D-alanine ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.10"^^xsd:string) "UDPacetylmuramoylpentapeptide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.10"^^xsd:string) "UDP-MurNAc-pentapeptide synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.10"^^xsd:string) "UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.10"^^xsd:string) "UDP-MurNAc-L-Ala-D-Glu-L-Lys:D-Ala-D-Ala ligase activity"^^xsd:string) AnnotationAssertion( "UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.10"^^xsd:string) "MurF synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.10"^^xsd:string) "uridine diphosphoacetylmuramoylpentapeptide synthetase activity"^^xsd:string) AnnotationAssertion( "UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.16"^^xsd:string) "D-alanine:alanyl-poly(glycerolphosphate) ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.16"^^xsd:string) Annotation( "MetaCyc:6.3.2.16-RXN"^^xsd:string) "Catalysis of the reaction: alanyl-poly(glycerolphosphate) + D-alanine + ATP = D-alanyl-alanyl-poly(glycerolphosphate) + phosphate + ADP."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.16"^^xsd:string) "D-alanine-membrane acceptor-ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-alanine-alanyl-poly(glycerolphosphate) ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.16"^^xsd:string) "D-alanyl-poly(phosphoglycerol) synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.16"^^xsd:string) "D-alanine:membrane-acceptor ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.16"^^xsd:string) "D-alanylalanylpoly(phosphoglycerol) synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.16"^^xsd:string) "D-alanyl-alanyl-poly(glycerolphosphate) synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.7"^^xsd:string) Annotation( "RHEA:17972"^^xsd:string) "Catalysis of the reaction: L-lysine + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.7"^^xsd:string) "UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.7"^^xsd:string) "uridine diphospho-N-acetylmuramoylalanyl-D-glutamyllysine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.7"^^xsd:string) "L-lysine-adding enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.7"^^xsd:string) "UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine gamma-ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.7"^^xsd:string) "UPD-MurNAc-L-Ala-D-Glu:L-Lys ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.7"^^xsd:string) "MurE synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.4.8"^^xsd:string) Annotation( "RHEA:16488"^^xsd:string) "Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H(2)O + imidazol-4-ylacetate = 1-(5-phosphoribosyl)imidazol-4-ylacetate + ADP + diphosphate + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.8"^^xsd:string) "imidazoleacetate:5-phosphoribosyl-diphosphate ligase (ADP- and diphosphate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "imidazoleacetate-phosphoribosyldiphosphate ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.8"^^xsd:string) "5-phosphoribosylimidazoleacetate synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein N-terminus binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jsg"^^xsd:string) "NH2-terminus binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jsg"^^xsd:string) "N-terminal end binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue."^^xsd:string) AnnotationAssertion(Annotation( "GOC:jsg"^^xsd:string) "amino-terminal binding"^^xsd:string) AnnotationAssertion( "N-terminal binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jsg"^^xsd:string) "NH2-terminal binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jsg"^^xsd:string) "amino-terminus binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.2.4"^^xsd:string) "Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups."^^xsd:string) AnnotationAssertion(rdfs:label "chondroitin ABC lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.2.6"^^xsd:string) "oligogalacturonate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.6"^^xsd:string) Annotation( "MetaCyc:OLIGOGALACTURONIDE-LYASE-RXN"^^xsd:string) "Catalysis of the reaction: 4-(4-deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate = 2 5-dehydro-4-deoxy-D-glucuronate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.6"^^xsd:string) "OGTE"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.6"^^xsd:string) "unsaturated oligogalacturonate transeliminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oligogalacturonide lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.2.7"^^xsd:string) "heparinase activity"^^xsd:string) AnnotationAssertion( "heparan sulfate lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "heparin lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.7"^^xsd:string) "heparin eliminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.7"^^xsd:string) Annotation( "MetaCyc:4.2.2.7-RXN"^^xsd:string) "Catalysis of the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their nonreducing ends."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.2.9"^^xsd:string) "exopolygalacturonate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.9"^^xsd:string) "exopectic acid transeliminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.9"^^xsd:string) "exopectate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.9"^^xsd:string) "exopolygalacturonic acid-trans-eliminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.9"^^xsd:string) "exo-PATE"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.9"^^xsd:string) "Exo-PATE activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.9"^^xsd:string) "PATE activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.9"^^xsd:string) "Catalysis of the reaction: a pectate = a pectate + 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate. This reaction is the eliminative cleavage of 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate from the reducing end of pectate, i.e. de-esterified pectin."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.9"^^xsd:string) "Exo-PGL activity"^^xsd:string) AnnotationAssertion(rdfs:label "pectate disaccharide-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.9"^^xsd:string) "pectate exo-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.9"^^xsd:string) "exo-PGL"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.9"^^xsd:string) "(1->4)-alpha-D-galacturonan reducing-end-disaccharide-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.2.10"^^xsd:string) "(1->4)-6-O-methyl-alpha-D-galacturonan lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.10"^^xsd:string) "polymethylgalacturonic transeliminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.10"^^xsd:string) "PMGL activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.10"^^xsd:string) "PL activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.10"^^xsd:string) "pectolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.10"^^xsd:string) "Catalysis of the reaction: a pectin = an oligosaccharide with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronate end + a pectin. This reaction is the eliminative cleavage of (1->4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their nonreducing ends."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.10"^^xsd:string) "endo-pectin lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pectin lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.10"^^xsd:string) "PNL activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.10"^^xsd:string) "pectin methyltranseliminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.10"^^xsd:string) "pectin trans-eliminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "poly(alpha-L-guluronate) lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.11"^^xsd:string) "L-guluronate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.11"^^xsd:string) "guluronate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.11"^^xsd:string) "alginase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.11"^^xsd:string) "poly-alpha-L-guluronate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.11"^^xsd:string) "Catalysis of the reaction: polysaccharides containing a terminal alpha-L-guluronate group = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing a terminal a-L-guluronate group, to give oligopolysaccharides with 4-deoxy-a-L-erythro-hex-4-enuronosyl groups at their nonreducing ends."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.11"^^xsd:string) "L-guluronan lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.11"^^xsd:string) "polyguluronate-specific alginate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.2.11"^^xsd:string) "poly(alpha-L-1,4-guluronide) exo-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.2.12"^^xsd:string) "Catalysis of the reaction: xanthan = oligosaccharide with 4-deoxy-alpha-L-threo-hex-4-enuronosyl end + pyruvylate mannose. This reaction is the eliminative cleavage of the terminal beta-D-mannosyl-beta-D-1,4-glucuronosyl linkage of the side-chain of the polysaccharide xanthan, leaving a 4-deoxy-alpha-L-threo-hex-4-enuronosyl group at the terminus of the side-chain."^^xsd:string) AnnotationAssertion(rdfs:label "xanthan lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.3"^^xsd:string) Annotation( "RHEA:16276"^^xsd:string) "Catalysis of the reaction: CDP-choline + ceramide = CMP + H(+) + sphingomyelin."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.3"^^xsd:string) "phosphorylcholine-ceramide transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ceramide cholinephosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.3"^^xsd:string) "CDP-choline:N-acylsphingosine cholinephosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.4"^^xsd:string) "serinephosphoethanolamine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.4"^^xsd:string) "CDP-ethanolamine:L-serine ethanolamine phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.4"^^xsd:string) "serine-phosphinico-ethanolamine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.4"^^xsd:string) Annotation( "RHEA:22659"^^xsd:string) "Catalysis of the reaction: L-serine + CDP-ethanolamine = L-serine-phosphoethanolamine + CMP + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.4"^^xsd:string) "serine ethanolamine phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.4"^^xsd:string) "serine ethanolaminephosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "serine-phosphoethanolamine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.4"^^xsd:string) "serine ethanolamine phosphodiester synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.21"^^xsd:string) "periplasmic phosphoglycerotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.21"^^xsd:string) "membrane-derived-oligosaccharide-6-(glycerophospho)-D-glucose:membrane-derived-oligosaccharide-D-glucose glycerophosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.21"^^xsd:string) "phosphoglycerol cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.21"^^xsd:string) "Catalysis of the transfer of a glycerophospho group from one membrane-derived oligosaccharide to another."^^xsd:string) AnnotationAssertion(rdfs:label "membrane-oligosaccharide glycerophosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcium-dependent phospholipase A2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.4"^^xsd:string) "Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction requires Ca2+."^^xsd:string) AnnotationAssertion( "calcium-dependent secreted phospholipase A2 activity"^^xsd:string) AnnotationAssertion( "calcium-dependent cytosolic phospholipase A2 activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "calcium-independent cytosolic phospholipase A2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.4"^^xsd:string) "Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction does not require Ca2+."^^xsd:string) AnnotationAssertion(rdfs:label "calcium-independent phospholipase A2 activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.198"^^xsd:string) Annotation( "RHEA:17332"^^xsd:string) "Catalysis of the reaction: (+)-borneol + NAD(+) = (1R, 4R)-camphor + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.198"^^xsd:string) "(+)-borneol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(+)-borneol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.198"^^xsd:string) "bicyclic monoterpenol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.208"^^xsd:string) "monoterpenoid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.208"^^xsd:string) "(+)-neomenthol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(+)-neomenthol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.208"^^xsd:string) Annotation( "RHEA:23815"^^xsd:string) "Catalysis of the reaction: (+)-neomenthol + NADP(+) = (2S,5R)-menthone + H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.228"^^xsd:string) Annotation( "RHEA:18332"^^xsd:string) "Catalysis of the reaction: (+)-cis-sabinol + NAD(+) = (1S,5S)-sabinone + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.228"^^xsd:string) "(+)-cis-sabinol dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(+)-sabinol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.228"^^xsd:string) "(+)-cis-sabinol:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.227"^^xsd:string) Annotation( "RHEA:22131"^^xsd:string) "Catalysis of the reaction: (-)-borneol + NAD(+) = (1S,4S)-camphor + H(+) + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "(-)-borneol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.227"^^xsd:string) "(-)-borneol:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(-)-menthol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.207"^^xsd:string) "monoterpenoid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.207"^^xsd:string) "(-)-menthol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.207"^^xsd:string) Annotation( "RHEA:13920"^^xsd:string) "Catalysis of the reaction: (-)-menthol + NADP(+) = (2S,5R)-menthone + H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(-)-menthol monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.46"^^xsd:string) "l-menthol monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.46"^^xsd:string) Annotation( "RHEA:11651"^^xsd:string) "Catalysis of the reaction: (-)-menthol + H(+) + NADPH + O(2) = 1,4-menthane-3,8-diol + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.46"^^xsd:string) "(-)-menthol,NADPH:oxygen oxidoreductase (8-hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.4.11"^^xsd:string) "ATP:(d)AMP phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.11"^^xsd:string) Annotation( "MetaCyc:DEOXYADENYLATE-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + dAMP = ADP + dADP."^^xsd:string) AnnotationAssertion(rdfs:label "(deoxy)adenylate kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.4.13"^^xsd:string) Annotation( "MetaCyc:DEOXYNUCLEOSIDE-PHOSPHATE-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + deoxynucleoside phosphate = ADP + deoxynucleoside diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.13"^^xsd:string) "deoxynucleoside monophosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.13"^^xsd:string) "deoxynucleoside-5'-monophosphate kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(deoxy)nucleoside-phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.13"^^xsd:string) "ATP:deoxynucleoside-phosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.13"^^xsd:string) "deoxyribonucleoside monophosphokinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.35"^^xsd:string) Annotation( "RHEA:22335"^^xsd:string) "Catalysis of the reaction: (R)-citramalate = 2-methylmaleate + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.35"^^xsd:string) "(-)-citramalate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.35"^^xsd:string) "citraconase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.35"^^xsd:string) "citraconate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.35"^^xsd:string) "(R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.35"^^xsd:string) "citramalate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.35"^^xsd:string) "(R)-2-methylmalate hydro-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(R)-2-methylmalate dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(R)-dehydropantoate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.33"^^xsd:string) "D-2-hydroxy-3,3-dimethyl-3-formylpropionate:diphosphopyridine nucleotide (DPN+) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.33"^^xsd:string) "(R)-4-dehydropantoate:NAD+ 4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.33"^^xsd:string) Annotation( "RHEA:19352"^^xsd:string) "Catalysis of the reaction: (R)-4-dehydropantoate + H(2)O + NAD(+) = (R)-3,3-dimethylmalate + 2 H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.33"^^xsd:string) "D-aldopantoate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(S)-2-methylmalate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.34"^^xsd:string) Annotation( "RHEA:13532"^^xsd:string) "Catalysis of the reaction: S-citramalate = H(2)O + mesaconate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.34"^^xsd:string) "(S)-2-methylmalate hydro-lyase (2-methylfumarate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.34"^^xsd:string) "citramalate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.34"^^xsd:string) "(+)-citramalic hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.34"^^xsd:string) "L-citramalate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.34"^^xsd:string) "mesaconate mesaconase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.34"^^xsd:string) "(+)-citramalate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.34"^^xsd:string) "mesaconase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.34"^^xsd:string) "mesaconate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.34"^^xsd:string) "(S)-2-methylmalate hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.2.17"^^xsd:string) Annotation( "RHEA:17348"^^xsd:string) "Catalysis of the reaction: (S)-methylmalonyl-CoA + H(2)O = CoA + H(+) + methylmalonate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.17"^^xsd:string) "D-methylmalonyl-coenzyme A hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(S)-methylmalonyl-CoA hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(S,S)-butanediol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.76"^^xsd:string) "L-butanediol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.76"^^xsd:string) "L-BDH"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.76"^^xsd:string) Annotation( "RHEA:12187"^^xsd:string) "Catalysis of the reaction: (S,S)-butane-2,3-diol + NAD(+) = acetoin + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.76"^^xsd:string) "(S,S)-butane-2,3-diol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.76"^^xsd:string) "L(+)-2,3-butanediol dehydrogenase (L-acetoin forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.63"^^xsd:string) Annotation( "MetaCyc:12-ALPHA-L-FUCOSIDASE-RXN"^^xsd:string) "Catalysis of the reaction: H2O + methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside = L-fucose + methyl beta-D-galactoside."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.63"^^xsd:string) "2-alpha-L-fucopyranosyl-beta-D-galactoside fucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.63"^^xsd:string) "almond emulsin fucosidase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.63"^^xsd:string) "alpha-(1->2)-L-fucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.63"^^xsd:string) "almond emulsin fucosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1,2-alpha-L-fucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "1,3-beta-glucan phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.97"^^xsd:string) "laminarin phosphorylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1,3-beta-D-glucan phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.97"^^xsd:string) "1,3-beta-D-glucan:orthophosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.97"^^xsd:string) Annotation( "MetaCyc:13-BETA-GLUCAN-PHOSPHORYLASE-RXN"^^xsd:string) "Catalysis of the reaction: [(1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate; substrates include laminarin."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.97"^^xsd:string) "laminarin phosphoryltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.97"^^xsd:string) "1,3-beta-D-glucan:phosphate alpha-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.30"^^xsd:string) "1,3-beta-D-oligoglucan:phosphate alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.30"^^xsd:string) Annotation( "MetaCyc:13-BETA-OLIGOGLUCAN-PHOSPHORYLASE-RXN"^^xsd:string) "Catalysis of the reaction: [oligomeric (1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.30"^^xsd:string) "beta-1,3-oligoglucan:orthophosphate glucosyltransferase II activity"^^xsd:string) AnnotationAssertion(rdfs:label "1,3-beta-oligoglucan phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.30"^^xsd:string) "beta-1,3-oligoglucan phosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.202"^^xsd:string) "3-hydroxypropionaldehyde reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.202"^^xsd:string) "1,3-PD:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.202"^^xsd:string) "propane-1,3-diol:NAD+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.202"^^xsd:string) "1,3-propanediol oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.202"^^xsd:string) Annotation( "MetaCyc:13-PROPANEDIOL-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.202"^^xsd:string) "1,3-propanediol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1,3-propanediol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.24"^^xsd:string) "xylan synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.24"^^xsd:string) "xylan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.24"^^xsd:string) Annotation( "MetaCyc:1,4-BETA-D-XYLAN-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: UDP-D-xylose + [(1->4)-beta-D-xylan](n) = UDP + [(1->4)-beta-D-xylan](n+1)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.24"^^xsd:string) "1,4-beta-xylan synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1,4-beta-D-xylan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.24"^^xsd:string) "uridine diphosphoxylose-1,4-beta-xylan xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.24"^^xsd:string) "UDP-D-xylose:1,4-beta-D-xylan 4-beta-D-xylosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.13"^^xsd:string) "1-methyladenosine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.13"^^xsd:string) Annotation( "RHEA:12868"^^xsd:string) "Catalysis of the reaction: 1-methyladenosine + H(2)O = 1-methyladenine + ribofuranose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.13"^^xsd:string) "1-methyladenosine ribohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-methyladenosine nucleosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.5.8"^^xsd:string) Annotation( ) "quinate:quinone 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.8"^^xsd:string) "NAD(P)-independent quinate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:23675"^^xsd:string) "Catalysis of the reaction: (-)-quinate + pyrroloquinoline-quinone = (-)-3-dehydroquinate + pyrroloquinoline-quinol."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.8"^^xsd:string) "quinate:pyrroloquinoline-quinone 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "quinate dehydrogenase (quinone) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "11-cis-retinyl-palmitate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.63"^^xsd:string) "11-cis-retinyl-palmitate acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.63"^^xsd:string) "11-cis-retinol palmitate esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.63"^^xsd:string) Annotation( "RHEA:19700"^^xsd:string) "Catalysis of the reaction: 11-cis-retinyl palmitate + H(2)O = 11-cis-retinol + H(+) + palmitate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.63"^^xsd:string) "RPH"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.238"^^xsd:string) "12beta-hydroxysteroid:NADP+ 12-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.238"^^xsd:string) Annotation( "RHEA:21427"^^xsd:string) "Catalysis of the reaction: 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate + NADP(+) = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.238"^^xsd:string) "12beta-hydroxysteroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.238"^^xsd:string) "12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.238"^^xsd:string) "12-beta-hydroxysteroid dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.48"^^xsd:string) Annotation( "KEGG:R04556"^^xsd:string) Annotation( "KEGG:R04557"^^xsd:string) Annotation( "MetaCyc:15-OXOPROSTAGLANDIN-13-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ -> (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(rdfs:label "15-oxoprostaglandin 13-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.48"^^xsd:string) "(5Z)-(15S)-11alpha-hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta13-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.99.2"^^xsd:string) Annotation( "MetaCyc:16-HYDROXYSTEROID-EPIMERASE-RXN"^^xsd:string) "Catalysis of the reaction: 16-alpha-hydroxysteroid = 16-beta-hydroxysteroid."^^xsd:string) AnnotationAssertion(rdfs:label "16-hydroxysteroid epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.99.2"^^xsd:string) "16-hydroxysteroid 16-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.51"^^xsd:string) "HDR activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.51"^^xsd:string) "2'-hydroxy-2,3-dihydrodaidzein:NADP+ 2'-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.51"^^xsd:string) "2'-hydroxydihydrodaidzein:NADP+ 2'-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.51"^^xsd:string) "2'-hydroxydihydrodaidzein:NADP(+) 2'-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2'-hydroxydaidzein reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.51"^^xsd:string) Annotation( "MetaCyc:2'-HYDROXYDAIDZEIN-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: 2'-hydroxydihydrodaidzein + NADP+ = 2'-hydroxydaidzein + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.51"^^xsd:string) "NADPH:2'-hydroxydaidzein oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.45"^^xsd:string) "vestitone:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.45"^^xsd:string) "NADPH:2'-hydroxyisoflavone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.45"^^xsd:string) Annotation( "MetaCyc:2-HYDROXYISOFLAVONE-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: vestitone + NADP+ = 2'-hydroxyformononetin + NADPH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "2'-hydroxyisoflavone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.45"^^xsd:string) "isoflavone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.45"^^xsd:string) "2',7-dihydroxy-4',5'-methylenedioxyisoflavone reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.14"^^xsd:string) Annotation( "MetaCyc:1,3-DIHYDROXYBENZOATE--SERINE-LIGASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + 2,3-dihydroxybenzoate + L-serine = products of ATP breakdown + N-(2,3-dihydroxybenzoyl)-L-serine."^^xsd:string) AnnotationAssertion(rdfs:label "2,3-dihydroxybenzoate-serine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.14"^^xsd:string) "2,3-dihydroxybenzoylserine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.14"^^xsd:string) "N-(2,3-dihydroxybenzoyl)-serine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.14"^^xsd:string) "2,3-dihydroxybenzoate:L-serine ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.23"^^xsd:string) "2,3-dihydroxyindole:oxygen 2,3-oxidoreductase (decyclizing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.23"^^xsd:string) Annotation( "RHEA:19448"^^xsd:string) "Catalysis of the reaction: 2,3-dihydroxyindole + O(2) = anthranilate + CO(2) + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "2,3-dihydroxyindole 2,3-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3.32"^^xsd:string) "(2R,3S)-2,3-dimethylmalate pyruvate-lyase (propanoate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "2,3-dimethylmalate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.32"^^xsd:string) Annotation( "RHEA:10475"^^xsd:string) "Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = propanoate + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.32"^^xsd:string) "2,3-dimethylmalate pyruvate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.32"^^xsd:string) "(2R,3S)-2,3-dimethylmalate pyruvate-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2,4-diaminopentanoate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.12"^^xsd:string) Annotation( "MetaCyc:24-DIAMINOPENTANOATE-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: 2,4-diaminopentanoate + H2O + NAD(P)+ = 2-amino-4-oxopentanoate + NH3 + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.12"^^xsd:string) "2,4-diaminopentanoate:NAD(P)+ oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.12"^^xsd:string) "2,4-diaminopentanoic acid C4 dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.8"^^xsd:string) Annotation( "RHEA:16020"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + ornithine = 5-amino-2-oxopentanoate + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.8"^^xsd:string) "diamino-acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.8"^^xsd:string) "diamino acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.8"^^xsd:string) "diamino-acid aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2,5-diaminovalerate transaminase activity"^^xsd:string) AnnotationAssertion( "2,5-diaminovalerate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.8"^^xsd:string) "2,5-diaminopentanoate:2-oxoglutarate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.2.13"^^xsd:string) "cyclo(Gly-Gly) hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2,5-dioxopiperazine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.13"^^xsd:string) "cyclo(glycylglycine) hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.13"^^xsd:string) Annotation( "RHEA:21811"^^xsd:string) "Catalysis of the reaction: 2,5-dioxopiperazine + H(2)O = glycylglycine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.13"^^xsd:string) "2,5-dioxopiperazine amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.26"^^xsd:string) "2-oxoglutarate semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2,5-dioxovalerate dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.26"^^xsd:string) "2,5-dioxopentanoate:NADP+ 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.26"^^xsd:string) Annotation( "IMG:03338"^^xsd:string) Annotation( "MetaCyc:25-DIOXOVALERATE-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: 2,5-dioxopentanoate + NADP+ + H2O = 2-oxoglutarate + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.26"^^xsd:string) "alpha-ketoglutaric semialdehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.99.3"^^xsd:string) "acetohydroxy acid isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.3"^^xsd:string) "2-acetolactate methylmutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.3"^^xsd:string) Annotation( "MetaCyc:2-ACETOLACTATE-MUTASE-RXN"^^xsd:string) "Catalysis of the reaction: 2-acetolactate = 3-hydroxy-3-methyl-2-oxobutanoate."^^xsd:string) AnnotationAssertion(rdfs:label "2-acetolactate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.3"^^xsd:string) "acetolactate mutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-alkyn-1-ol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.165"^^xsd:string) Annotation( "RHEA:19104"^^xsd:string) "Catalysis of the reaction: 2-butyne-1,4-diol + NAD(+) = 4-hydroxy-2-butynal + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.165"^^xsd:string) "2-butyne-1,4-diol:NAD+ 1-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.39"^^xsd:string) "glutamate-alpha-ketoadipate transaminase activity"^^xsd:string) AnnotationAssertion( "2-aminoadipate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.39"^^xsd:string) Annotation( "RHEA:12604"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + L-2-aminoadipate = 2-oxoadipate + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.39"^^xsd:string) "2-aminoadipic aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.39"^^xsd:string) "glutamic-ketoadipic transaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-aminoadipate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.39"^^xsd:string) "alpha-aminoadipate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.39"^^xsd:string) "L-2-aminoadipate:2-oxoglutarate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.67"^^xsd:string) "L-2-aminohexanoate:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.67"^^xsd:string) "leucine L-norleucine: 2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-aminohexanoate transaminase activity"^^xsd:string) AnnotationAssertion( "2-aminohexanoate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.67"^^xsd:string) "norleucine (leucine) aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.67"^^xsd:string) "norleucine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.67"^^xsd:string) "norleucine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.67"^^xsd:string) Annotation( "MetaCyc:2-AMINOHEXANOATE-AMINOTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.63"^^xsd:string) "2-carboxyarabinitol 1-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.63"^^xsd:string) "2-carboxy-D-arabinitol 1-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-carboxy-D-arabinitol-1-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.63"^^xsd:string) Annotation( "RHEA:17840"^^xsd:string) "Catalysis of the reaction: 2-carboxy-D-arabinitol 1-phosphate + H(2)O = 2-carboxy-D-arabinitol + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.63"^^xsd:string) "2-carboxy-D-arabinitol-1-phosphate 1-phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.112"^^xsd:string) "2-deoxy-alpha-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.112"^^xsd:string) "2-deoxy-alpha-D-glucoside deoxyglucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.112"^^xsd:string) "2-deoxy-alpha-D-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.112"^^xsd:string) Annotation( "MetaCyc:2-DEOXYGLUCOSIDASE-RXN"^^xsd:string) "Catalysis of the reaction: H2O + a 2-deoxy-alpha-D-glucoside = 2-deoxy-D-glucose + an alcohol."^^xsd:string) AnnotationAssertion(rdfs:label "2-deoxyglucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.31"^^xsd:string) "butanoate:NAD+ delta2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.31"^^xsd:string) Annotation( "MetaCyc:2-ENOATE-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: butanoate + NAD+ = 2-butenoate + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.31"^^xsd:string) "enoate reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-enoate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.31"^^xsd:string) "2-furoyl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.31"^^xsd:string) Annotation( "RHEA:19272"^^xsd:string) "Catalysis of the reaction: 2-furoate + ATP + CoA = 2-furoyl-CoA + AMP + diphosphate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.31"^^xsd:string) "2-furoate:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "2-furoate-CoA ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.99.8"^^xsd:string) Annotation( "RHEA:21483"^^xsd:string) "Catalysis of the reaction: 2-furoyl-CoA + A + H(2)O = 5-hydroxy-2-furoyl-CoA + AH(2) + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "2-furoyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.8"^^xsd:string) "furoyl-CoA hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.8"^^xsd:string) "2-furoyl-CoA:(acceptor) 5-oxidoreductase (hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.8"^^xsd:string) "2-furoyl coenzyme A dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.8"^^xsd:string) "2-furoyl coenzyme A hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.8"^^xsd:string) "2-furoyl-CoA:acceptor 5-oxidoreductase (hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hexadecenal reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.27"^^xsd:string) "hexadecanal:NADP+ delta2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.27"^^xsd:string) Annotation( "RHEA:12447"^^xsd:string) "Catalysis of the reaction: NADP(+) + palmitaldehyde = trans-hexadec-2-enal + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.27"^^xsd:string) "hexadecanal: NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.44"^^xsd:string) Annotation( "RHEA:11999"^^xsd:string) "Catalysis of the reaction: biphenyl-2-ol + H(+) + NADH + O(2) = biphenyl-2,3-diol + H(2)O + NAD(+)."^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxybiphenyl 3-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.44"^^xsd:string) "2-hydroxybiphenyl,NADH:oxygen oxidoreductase (3-hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.2"^^xsd:string) "hydroxyglutaric dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.2"^^xsd:string) Annotation( "MetaCyc:2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.2"^^xsd:string) "L-alpha-hydroxyglutarate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxyglutarate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.2"^^xsd:string) "(S)-2-hydroxyglutarate:acceptor 2-oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.2"^^xsd:string) "alpha-hydroxyglutarate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.2"^^xsd:string) "alpha-ketoglutarate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.2"^^xsd:string) "(S)-2-hydroxyglutarate:(acceptor) 2-oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.2"^^xsd:string) "alpha-hydroxyglutarate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.2"^^xsd:string) "L-alpha-hydroxyglutarate:NAD+ 2-oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.2"^^xsd:string) "alpha-hydroxyglutarate dehydrogenase (NAD+ specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.26"^^xsd:string) Annotation( "RHEA:16976"^^xsd:string) "Catalysis of the reaction: 2-hydroxypyridine + AH(2) + O(2) = 2,5-dihydroxypyridine + A + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.26"^^xsd:string) "2-hydroxypyridine,hydrogen-donor:oxygen oxidoreductase (5-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.26"^^xsd:string) "2-hydroxypyridine oxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxypyridine 5-monooxygenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.79"^^xsd:string) "prpD"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.79"^^xsd:string) "(2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming]"^^xsd:string) AnnotationAssertion(rdfs:label "2-methylcitrate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.79"^^xsd:string) "2-methylcitrate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.79"^^xsd:string) Annotation( "RHEA:17728"^^xsd:string) "Catalysis of the reaction: (2S,3S)-2-methylcitrate = cis-2-methylaconitate + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.79"^^xsd:string) "2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-methyleneglutarate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.4"^^xsd:string) "2-methyleneglutarate carboxy-methylenemethylmutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.4"^^xsd:string) "alpha-methyleneglutarate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.4"^^xsd:string) Annotation( "RHEA:13796"^^xsd:string) "Catalysis of the reaction: 2-methyleneglutarate = 2-methylene-3-methylsuccinate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.31"^^xsd:string) Annotation( "RHEA:19460"^^xsd:string) "Catalysis of the reaction: 2-nitrophenol + 2 H(+) + 2 NADPH + O(2) = catechol + H(2)O + 2 NADP(+) + nitrite."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.31"^^xsd:string) "2-nitrophenol,NADPH:oxygen 2-oxidoreductase (2-hydroxylating, nitrite-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.31"^^xsd:string) "nitrophenol oxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-nitrophenol 2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.31"^^xsd:string) "2-nitrophenol oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-oxoadipate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.172"^^xsd:string) "alpha-ketoadipate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.172"^^xsd:string) "2-ketoadipate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.172"^^xsd:string) Annotation( "RHEA:14796"^^xsd:string) "Catalysis of the reaction: 2-hydroxyadipate + NAD(+) = 2-oxoadipate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.172"^^xsd:string) "2-hydroxyadipate:NAD+ 2-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-oxoaldehyde dehydrogenase (NAD) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.23"^^xsd:string) "alpha-ketoaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.23"^^xsd:string) "NAD-linked alpha-ketoaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.23"^^xsd:string) "NAD-dependent alpha-ketoaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.23"^^xsd:string) "2-oxoaldehyde dehydrogenase (NAD+)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.23"^^xsd:string) "2-oxoaldehyde:NAD+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.23"^^xsd:string) Annotation( "MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-NAD+-RXN"^^xsd:string) "Catalysis of the reaction: a 2-oxoaldehyde + NAD+ + H2O = a 2-oxo acid + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.23"^^xsd:string) "methylglyoxal dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.23"^^xsd:string) "2-ketoaldehyde dehydrogenase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.49"^^xsd:string) "alpha-ketoaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.49"^^xsd:string) "NADP-dependent alpha-ketoaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-oxoaldehyde dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.49"^^xsd:string) "methylglyoxal dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.49"^^xsd:string) "2-ketoaldehyde dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.49"^^xsd:string) Annotation( "MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-NADP+-RXN"^^xsd:string) "Catalysis of the reaction: a 2-oxoaldehyde + NADP+ + H2O = a 2-oxo acid + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.49"^^xsd:string) "2-oxoaldehyde:NADP+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.49"^^xsd:string) "NADP-linked alpha-ketoaldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.7.3"^^xsd:string) Annotation( "MetaCyc:2-OXOGLUTARATE-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + CoA + oxidized ferredoxin = succinyl-CoA + CO2 + reduced ferredoxin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.3"^^xsd:string) "2-oxoglutarate:ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.3"^^xsd:string) "2-oxoglutarate:ferredoxin 2-oxidoreductase (CoA-succinylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.3"^^xsd:string) "KGOR activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.3"^^xsd:string) "2-oxoglutarate ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.3"^^xsd:string) "alpha-ketoglutarate-ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-oxoglutarate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.3"^^xsd:string) "2-ketoglutarate ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.3"^^xsd:string) "alpha-ketoglutarate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.7.3"^^xsd:string) "2-oxoglutarate:ferredoxin 2-oxidoreductase (decarboxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-pyrone-4,6-dicarboxylate lactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.57"^^xsd:string) "2-pyrone-4,6-dicarboxylate lactonohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.57"^^xsd:string) Annotation( "RHEA:10647"^^xsd:string) "Catalysis of the reaction: 2-oxo-2H-pyran-4,6-dicarboxylate + H(2)O = 4-carboxy-2-hydroxyhexa-2,4-dienedioate + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cyclic GMP phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.35"^^xsd:string) "3',5'-cyclic-GMP 5'-nucleotidohydrolase activity"^^xsd:string) AnnotationAssertion( "guanosine cyclic 3',5'-phosphate phosphodiesterase activity"^^xsd:string) AnnotationAssertion( "cGMP phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.35"^^xsd:string) "cyclic guanosine 3',5'-phosphate phosphodiesterase activity"^^xsd:string) AnnotationAssertion( "3',5' cyclic-GMP phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.35"^^xsd:string) "cGMP-PDE"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.35"^^xsd:string) "cyclic guanosine 3',5'-monophosphate phosphodiesterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3',5'-cyclic-GMP phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.35"^^xsd:string) Annotation( "MetaCyc:35-CYCLIC-GMP-PHOSPHODIESTERASE-RXN"^^xsd:string) "Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.35"^^xsd:string) "cyclic 3',5'-GMP phosphodiesterase activity"^^xsd:string) AnnotationAssertion( "cGMP-specific phosphodiesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.69"^^xsd:string) "3,4-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.69"^^xsd:string) Annotation( "RHEA:18604"^^xsd:string) "Catalysis of the reaction: 3,4-dihydroxyphthalate + H(+) = 3,4-dihydroxybenzoate + CO(2)."^^xsd:string) AnnotationAssertion( "3,4-dihydroxyphthalate 2-decarboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3,4-dihydroxyphthalate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.69"^^xsd:string) "3,4-dihydroxyphthalate carboxy-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.3.5"^^xsd:string) "3-aci-nitropropanoate:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.3.5"^^xsd:string) "propionate-3-nitronate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.3.5"^^xsd:string) Annotation( "RHEA:22375"^^xsd:string) "Catalysis of the reaction: 3-aci-nitropropanoate + H(2)O + O(2) = 3-oxopropanoate + H(2)O(2) + nitrite."^^xsd:string) AnnotationAssertion(rdfs:label "3-aci-nitropropanoate oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.65"^^xsd:string) Annotation( "RHEA:15388"^^xsd:string) "Catalysis of the reaction: L-asparagine = 3-cyano-L-alanine + H(2)O + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.65"^^xsd:string) "beta-CNAla hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.65"^^xsd:string) "beta-cyanoalanine hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.65"^^xsd:string) "L-asparagine hydro-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-cyanoalanine hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.65"^^xsd:string) "L-asparagine hydro-lyase (3-cyanoalanine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.65"^^xsd:string) "beta-CNA nitrilase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.65"^^xsd:string) "beta-cyanoalanine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.130"^^xsd:string) "3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.130"^^xsd:string) "2,3-diketo-L-gulonate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.130"^^xsd:string) Annotation( "MetaCyc:3-DEHYDRO-L-GULONATE-2-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.130"^^xsd:string) "3-keto-L-gulonate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.130"^^xsd:string) "3-ketogulonate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-dehydro-L-gulonate 2-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.102"^^xsd:string) "D-3-oxosphinganine:B-NADPH oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.102"^^xsd:string) "D-3-oxosphinganine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.102"^^xsd:string) "3-oxosphinganine:NADPH oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.102"^^xsd:string) Annotation( "RHEA:22643"^^xsd:string) "Catalysis of the reaction: NADP(+) + sphinganine = 3-dehydrosphinganine + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.102"^^xsd:string) "KTS reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.102"^^xsd:string) "D-erythro-dihydrosphingosine:NADP+ 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.102"^^xsd:string) "DSR activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.102"^^xsd:string) "D-3-dehydrosphinganine reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-dehydrosphinganine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.102"^^xsd:string) "3-ketosphinganine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.102"^^xsd:string) "3-oxosphinganine reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.10.3.5"^^xsd:string) "3-hydroxyanthranilic acid oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxyanthranilate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.5"^^xsd:string) "3-hydroxyanthranilate:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.5"^^xsd:string) Annotation( "RHEA:17248"^^xsd:string) "Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H(2)O(2)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3.14"^^xsd:string) Annotation( "RHEA:14380"^^xsd:string) "Catalysis of the reaction: (3R)-3-hydroxy-L-aspartate = glycine + glyoxylate."^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxyaspartate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.14"^^xsd:string) "erythro-3-hydroxy-L(s)-aspartate glyoxylate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.14"^^xsd:string) "erythro-beta-hydroxyaspartate glycine-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.14"^^xsd:string) "erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.14"^^xsd:string) "erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase (glycine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.14"^^xsd:string) "erythro-beta-hydroxyaspartate aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-hydroxybenzoate 2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.23"^^xsd:string) "3-HBA-2-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.23"^^xsd:string) Annotation( "RHEA:14196"^^xsd:string) "Catalysis of the reaction: 3-hydroxybenzoate + AH(2) + O(2) = 2,3-dihydroxybenzoate + A + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.23"^^xsd:string) "3-hydroxybenzoate,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating)"^^xsd:string) AnnotationAssertion( "3-hydroxybenzoate 2-hydroxylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.26"^^xsd:string) Annotation( "RHEA:15908"^^xsd:string) "Catalysis of the reaction: 3-hydroxycyclohexanone + A = AH(2) + cyclohexane-1,3-dione."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.26"^^xsd:string) "3-hydroxycyclohexanone:acceptor 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxycyclohexanone dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-hydroxypropionate dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.59"^^xsd:string) "3-hydroxypropanoate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.59"^^xsd:string) Annotation( "RHEA:13360"^^xsd:string) "Catalysis of the reaction: 3-hydroxypropanoate + NAD(+) = 3-oxopropanoate + H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-ketovalidoxylamine C-N-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.3.1"^^xsd:string) "3-ketovalidoxylamine A C-N-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.3.1"^^xsd:string) "4-nitrophenyl-3-ketovalidamine 4-nitroaniline-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.3.1"^^xsd:string) "p-nitrophenyl-3-ketovalidamine p-nitroaniline lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.3.1"^^xsd:string) "4-nitrophenyl-3-ketovalidamine 4-nitroaniline-lyase [5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one-forming]"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.3.1"^^xsd:string) Annotation( "RHEA:22771"^^xsd:string) "Catalysis of the reaction: 4-nitrophenyl-3-ketovalidamine = 4-nitroaniline + 5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.17"^^xsd:string) Annotation( "RHEA:20260"^^xsd:string) "Catalysis of the reaction: 3-methyloxindole + NADP(+) = 3-methyleneoxindole + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.17"^^xsd:string) "3-methyl-1,3-dihydroindol-2-one:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.17"^^xsd:string) "3-methyloxindole:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-methyleneoxindole reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.99.6"^^xsd:string) "3-oxo-5beta-steroid:acceptor delta4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.6"^^xsd:string) "3-oxo-5beta-steroid:(acceptor) delta4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.6"^^xsd:string) "delta4-3-ketosteroid 5-beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.6"^^xsd:string) Annotation( "MetaCyc:3-OXO-5-BETA-STEROID-4-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: a 3-oxo-5-beta-steroid + acceptor = a 3-oxo-D4-steroid + reduced acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "3-oxo-5-beta-steroid 4-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.6"^^xsd:string) "3-oxo-5beta-steroid 4-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.3.6"^^xsd:string) "beta-ketoadipate:succinyl-CoA transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.6"^^xsd:string) "3-oxoadipate succinyl-CoA transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.6"^^xsd:string) Annotation( "MetaCyc:3-OXOADIPATE-COA-TRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.6"^^xsd:string) "succinyl-CoA:3-oxoadipate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.6"^^xsd:string) "3-oxoadipate coenzyme A-transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-oxoadipate CoA-transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-oxoadipate enol-lactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.24"^^xsd:string) "beta-ketoadipic enol-lactone hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.24"^^xsd:string) "beta-ketoadipate enol-lactone hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.24"^^xsd:string) "carboxymethylbutenolide lactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.24"^^xsd:string) "3-ketoadipate enol-lactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.24"^^xsd:string) "4-carboxymethylbut-3-en-4-olide enol-lactonohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.24"^^xsd:string) "3-oxoadipic enol-lactone hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.24"^^xsd:string) Annotation( "MetaCyc:3-OXOADIPATE-ENOL-LACTONASE-RXN"^^xsd:string) "Catalysis of the reaction: 3-oxoadipate enol-lactone + H2O = 3-oxoadipate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.99.4"^^xsd:string) "3-oxosteroid:(acceptor) delta1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.4"^^xsd:string) "3-ketosteroid-1-en-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.4"^^xsd:string) "4-en-3-oxosteroid:(acceptor)-1-en-oxido-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.4"^^xsd:string) "delta1-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.4"^^xsd:string) "3-oxosteroid delta1-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.4"^^xsd:string) "3-oxosteroid:(2,6-dichlorphenolindophenol) delta1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.4"^^xsd:string) "delta1-steroid reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.4"^^xsd:string) "3-ketosteroid-delta1-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.4"^^xsd:string) "1-ene-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.4"^^xsd:string) Annotation( "MetaCyc:3-OXOSTEROID-1-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: a 3-oxosteroid + acceptor = a 3-oxo-D1-steroid + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.4"^^xsd:string) "3-oxosteroid:acceptor delta1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-oxosteroid 1-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.38"^^xsd:string) "D-3-phosphoglycerate phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-phosphoglycerate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.38"^^xsd:string) "D-glycerate-3-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.38"^^xsd:string) Annotation( "RHEA:12415"^^xsd:string) "Catalysis of the reaction: 3-phospho-D-glycerate + H(2)O = D-glycerate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.38"^^xsd:string) "3-PGA phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.63"^^xsd:string) "4-acetamidobutanoate amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-acetamidobutyrate deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.63"^^xsd:string) Annotation( "MetaCyc:4-ACETAMIDOBUTYRATE-DEACETYLASE-RXN"^^xsd:string) "Catalysis of the reaction: 4-acetamidobutanoate + H2O = acetate + 4-aminobutanoate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.51"^^xsd:string) "aminobutyryl-CoA thiolesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.51"^^xsd:string) "4-acetamidobutanoyl-CoA amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-acetamidobutyryl-CoA deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.51"^^xsd:string) "deacetylase-thiolesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.51"^^xsd:string) Annotation( "RHEA:22931"^^xsd:string) "Catalysis of the reaction: 4-acetamidobutanoyl-CoA + H(2)O = 4-aminobutanoyl-CoA + acetate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.44"^^xsd:string) "4-carboxymuconolactone carboxy-lyase (4,5-dihydro-5-oxofuran-2-acetate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.44"^^xsd:string) "4-carboxymuconolactone carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.44"^^xsd:string) "gamma-4-carboxymuconolactone decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.44"^^xsd:string) Annotation( "RHEA:23351"^^xsd:string) "Catalysis of the reaction: (R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate + H(+) = 5-oxo-4,5-dihydro-2-furylacetate + CO(2)."^^xsd:string) AnnotationAssertion(rdfs:label "4-carboxymuconolactone decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.44"^^xsd:string) "4-carboxymonolactone carboxy-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.8.1.6"^^xsd:string) Annotation( "RHEA:23443"^^xsd:string) "Catalysis of the reaction: 4-chlorobenzoate + H(2)O = 4-hydroxybenzoate + chloride + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "4-chlorobenzoate dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.6"^^xsd:string) "halobenzoate dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.6"^^xsd:string) "4-chlorobenzoate chlorohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.61"^^xsd:string) "gamma-hydroxybutyrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.61"^^xsd:string) Annotation( "RHEA:23951"^^xsd:string) "Catalysis of the reaction: 4-hydroxybutanoate + NAD(+) = H(+) + NADH + succinate semialdehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.61"^^xsd:string) "4-hydroxybutanoate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxybutyrate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "4-hydroxyglutamate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxyglutamate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.23"^^xsd:string) Annotation( "MetaCyc:4-HYDROXYGLUTAMATE-AMINOTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: 4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.23"^^xsd:string) "4-hydroxy-L-glutamate:2-oxoglutarate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.19"^^xsd:string) "(S)-2-hydroxy-2-(4-hydroxyphenyl)acetate:oxygen 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.19"^^xsd:string) Annotation( "RHEA:15836"^^xsd:string) "Catalysis of the reaction: (S)-4-hydroxymandelate + H(+) + O(2) = 4-hydroxybenzaldehyde + CO(2) + H(2)O(2)."^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxymandelate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.19"^^xsd:string) "L-4-hydroxymandelate oxidase (decarboxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-hydroxyproline epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.8"^^xsd:string) "4-hydroxyproline 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.8"^^xsd:string) Annotation( "RHEA:21155"^^xsd:string) "Catalysis of the reaction: trans-4-hydroxy-L-proline = cis-4-hydroxy-D-proline."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.8"^^xsd:string) "L-hydroxyproline epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.8"^^xsd:string) "hydroxyproline 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.8"^^xsd:string) "hydroxyproline epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-methyleneglutamate-ammonia ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.7"^^xsd:string) Annotation( "RHEA:13856"^^xsd:string) "Catalysis of the reaction: 4-methylene-L-glutamate + ATP + NH(4)(+) = 4-methylene-L-glutamine + AMP + diphosphate + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.7"^^xsd:string) "4-methyleneglutamine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.7"^^xsd:string) "4-methylene-L-glutamate:ammonia ligase (AMP-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.67"^^xsd:string) Annotation( "RHEA:14744"^^xsd:string) "Catalysis of the reaction: 4-methylene-L-glutamine + H(2)O = 4-methylene-L-glutamate + NH(4)(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.67"^^xsd:string) "4-methylene-L-glutamine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.67"^^xsd:string) "4-methyleneglutamine deamidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-methyleneglutaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.67"^^xsd:string) "4-methyleneglutamine amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.44"^^xsd:string) "oxaloacetate-4-methyl-ester oxaloacetohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-methyloxaloacetate esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.44"^^xsd:string) Annotation( "RHEA:10567"^^xsd:string) "Catalysis of the reaction: 4-methoxy-2,4-dioxobutanoate + H(2)O = H(+) + methanol + oxaloacetate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-oxalmesaconate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.83"^^xsd:string) "2-hydroxy-4-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.83"^^xsd:string) "4-carboxy-2-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.83"^^xsd:string) "4-carboxy-2-oxohexenedioate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.83"^^xsd:string) Annotation( "RHEA:17404"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.83"^^xsd:string) "oxalmesaconate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.83"^^xsd:string) "2-hydroxy-4-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase [(E)-4-oxobut-1-ene-1,2,4-tricarboxylate-forming]"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.83"^^xsd:string) "gamma-oxalmesaconate hydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.27"^^xsd:string) "4-pyridoxolactone lactonohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-pyridoxolactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.27"^^xsd:string) Annotation( "RHEA:14304"^^xsd:string) "Catalysis of the reaction: 4-pyridoxolactone + H(2)O = 4-pyridoxate + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5'-acylphosphoadenosine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.20"^^xsd:string) Annotation( "MetaCyc:5-ACYLPHOSPHOADENOSINE-HYDROLASE-RXN"^^xsd:string) "Catalysis of the reaction: 5'-acylphosphoadenosine + H2O = AMP + a carboxylate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.20"^^xsd:string) "5-phosphoadenosine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.20"^^xsd:string) "5'-acylphosphoadenosine acylhydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.62"^^xsd:string) "5alpha-ergosta-7,22-diene-3beta,5-diol 5,6-hydro-lyase (ergosterol-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.62"^^xsd:string) "5alpha-hydroxysteroid dehydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "5-alpha-hydroxysteroid dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.62"^^xsd:string) Annotation( "RHEA:22067"^^xsd:string) "Catalysis of the reaction: 5alpha-ergosta-7,22-diene-3beta,5-diol = ergosterol + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.62"^^xsd:string) "5alpha-ergosta-7,22-diene-3beta,5-diol 5,6-hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.30"^^xsd:string) Annotation( "MetaCyc:5-AMINOPENTANAMIDASE-RXN"^^xsd:string) "Catalysis of the reaction: 5-aminopentanamide + H2O = 5-aminopentanoate + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.30"^^xsd:string) "5-aminonorvaleramidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.30"^^xsd:string) "5-aminovaleramidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "5-aminopentanamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.30"^^xsd:string) "5-aminopentanamide amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.48"^^xsd:string) Annotation( "RHEA:10215"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + 5-aminopentanoate = 5-oxopentanoate + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.48"^^xsd:string) "delta-aminovalerate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "5-aminovalerate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.48"^^xsd:string) "5-aminopentanoate:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion( "5-aminovalerate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.48"^^xsd:string) "delta-aminovalerate transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.92"^^xsd:string) "ATP:5-dehydro-2-deoxy-D-gluconate 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "5-dehydro-2-deoxygluconokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.92"^^xsd:string) "5-keto-2-deoxygluconokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.92"^^xsd:string) Annotation( "MetaCyc:5-DEHYDRO-2-DEOXYGLUCONOKINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + 5-dehydro-2-deoxy-D-gluconate = ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.92"^^xsd:string) "DKH kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.92"^^xsd:string) "5-keto-2-deoxyglucono kinase (phosphorylating)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.3.14"^^xsd:string) Annotation( "RHEA:23499"^^xsd:string) "Catalysis of the reaction: 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.14"^^xsd:string) "acetyl-CoA:5-hydroxypentanoate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.14"^^xsd:string) "5-hydroxyvalerate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.14"^^xsd:string) "5-hydroxyvalerate coenzyme A transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "5-hydroxypentanoate CoA-transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.12.5"^^xsd:string) "5-pyridoxate,NADPH:oxygen oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.5"^^xsd:string) Annotation( "RHEA:11155"^^xsd:string) "Catalysis of the reaction: 5-pyridoxate + NADPH + O(2) = (2Z)-2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP(+)."^^xsd:string) AnnotationAssertion(rdfs:label "5-pyridoxate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.12.5"^^xsd:string) "5-pyridoxate oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.33"^^xsd:string) "6-O-acetylglucose deacetylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "6-acetylglucose deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.33"^^xsd:string) "6-acetyl-D-glucose acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.33"^^xsd:string) Annotation( "RHEA:18488"^^xsd:string) "Catalysis of the reaction: 6-acetyl-D-glucose + H(2)O = D-glucose + acetate + H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.14"^^xsd:string) "hydroxyhyoscyamine dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.14"^^xsd:string) Annotation( "RHEA:12800"^^xsd:string) "Catalysis of the reaction: (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O(2) = CO(2) + H(2)O + H(+) + scopolamine + succinate."^^xsd:string) AnnotationAssertion(rdfs:label "6-beta-hydroxyhyoscyamine epoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.14"^^xsd:string) "6beta-hydroxyhyoscyamine epoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.14"^^xsd:string) "(6S)-6-hydroxyhyoscyamine,2-oxoglutarate oxidoreductase (epoxide-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "6-hydroxynicotinate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.1"^^xsd:string) "6-oxotetrahydro-nicotinate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.1"^^xsd:string) "6-hydroxynicotinic reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.1"^^xsd:string) "6-oxo-1,4,5,6-tetrahydronicotinate:ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.1"^^xsd:string) "6-oxotetrahydronicotinate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.1"^^xsd:string) "HNA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.1"^^xsd:string) "1,4,5,6-tetrahydro-6-oxonicotinate:ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.1"^^xsd:string) Annotation( "MetaCyc:6-HYDROXYNICOTINATE-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized ferredoxin = 6-hydroxynicotinate + reduced ferredoxin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.52"^^xsd:string) "6-methylsalicylate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.52"^^xsd:string) "6-methylsalicylate carboxy-lyase (3-cresol-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "6-methylsalicylate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.52"^^xsd:string) Annotation( "RHEA:23115"^^xsd:string) "Catalysis of the reaction: 6-methylsalicylate + H(+) = 3-cresol + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.52"^^xsd:string) "6-methylsalicylic acid (2,6-cresotic acid) decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.52"^^xsd:string) "6-MSA decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.51"^^xsd:string) "6-oxocineole,NADPH:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "6-oxocineole dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.51"^^xsd:string) Annotation( "RHEA:24327"^^xsd:string) "Catalysis of the reaction: 6-oxocineole + H(+) + NADPH + O(2) = 1,6,6-trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.51"^^xsd:string) "6-oxocineole oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.21"^^xsd:string) "cholesterol:NADP+ delta7-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.21"^^xsd:string) "7-DHC reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "7-dehydrocholesterol reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.21"^^xsd:string) "Catalysis of the reaction: cholesterol + NADP+ = cholesta-5,7-dien-3-beta-ol + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.21"^^xsd:string) "sterol Delta(7)-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.21"^^xsd:string) "sterol delta7-reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "8-oxocoformycin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.235"^^xsd:string) "coformycin:NADP+ 8-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.235"^^xsd:string) "8-ketodeoxycoformycin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.235"^^xsd:string) Annotation( "RHEA:23171"^^xsd:string) "Catalysis of the reaction: coformycin + NADP(+) = 8-oxocoformycin + 2 H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.60"^^xsd:string) Annotation( "MetaCyc:ABEQUOSYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: CDP-abequose + D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid = CDP + D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid."^^xsd:string) AnnotationAssertion(rdfs:label "abequosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.60"^^xsd:string) "CDP-abequose:D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid D-abequosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.60"^^xsd:string) "trihexose diphospholipid abequosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acetate kinase (diphosphate) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.12"^^xsd:string) Annotation( "RHEA:24279"^^xsd:string) "Catalysis of the reaction: acetate + diphosphate = acetyl phosphate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.12"^^xsd:string) "acetate kinase (pyrophosphate) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.12"^^xsd:string) "diphosphate:acetate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.12"^^xsd:string) "pyrophosphate-acetate phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acetoacetate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.4"^^xsd:string) "acetoacetate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.4"^^xsd:string) "acetoacetic acid decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.4"^^xsd:string) Annotation( "RHEA:19732"^^xsd:string) "Catalysis of the reaction: acetoacetate + H(+) = acetone + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.4"^^xsd:string) "acetoacetate carboxy-lyase (acetone-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.2.11"^^xsd:string) "acetoacetyl coenzyme A hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.11"^^xsd:string) "acetoacetyl CoA deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.11"^^xsd:string) "acetoacetyl coenzyme A deacylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetoacetyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.11"^^xsd:string) Annotation( "RHEA:15676"^^xsd:string) "Catalysis of the reaction: acetoacetyl-CoA + H(2)O = acetoacetate + CoA + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.2.4"^^xsd:string) "acetylmethylcarbinol racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.2.4"^^xsd:string) Annotation( "RHEA:12095"^^xsd:string) "Catalysis of the reaction: (S)-acetoin = (R)-acetoin."^^xsd:string) AnnotationAssertion(rdfs:label "acetoin racemase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.5"^^xsd:string) "alpha-acetolactate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.5"^^xsd:string) Annotation( "MetaCyc:ACETOLACTATE-DECARBOXYLASE-RXN"^^xsd:string) "Catalysis of the reaction: (S)-2-hydroxy-2-methyl-3-oxobutanoate = (R)-2-acetoin + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.5"^^xsd:string) "(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetolactate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.5"^^xsd:string) "(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase [(R)-2-acetoin-forming]"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.37"^^xsd:string) "2-hydroxyisobutyronitrile acetone-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.37"^^xsd:string) "acetone-cyanohydrin acetone-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.37"^^xsd:string) "acetone-cyanhydrin lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydroxynitrilase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.37"^^xsd:string) "oxynitrilase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.37"^^xsd:string) "acetone-cyanohydrin acetone-lyase (cyanide-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4..1.2.37"^^xsd:string) "acetone-cyanohydrin lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "hydroxynitrile lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "MetaCyc:ACETONE-CYANHYDRIN-LYASE-RXN"^^xsd:string) "Catalysis of the reaction: a hydroxynitrile = cyanide + an aldehyde or ketone."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.37"^^xsd:string) "2-hydroxyisobutyronitrile acetone-lyase (cyanide-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.37"^^xsd:string) "alpha-hydroxynitrile lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.37"^^xsd:string) "(S)-acetone-cyanohydrin lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acetylindoxyl oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.3.2"^^xsd:string) Annotation( "MetaCyc:ACETYLINDOXYL-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: N-acetylindoxyl + O2 = N-acetylisatin + unknown."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.3.2"^^xsd:string) "N-acetylindoxyl:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.62"^^xsd:string) Annotation( "RHEA:23415"^^xsd:string) "Catalysis of the reaction: N-acetylputrescine + H(2)O = acetate + putrescine."^^xsd:string) AnnotationAssertion(rdfs:label "acetylputrescine deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.62"^^xsd:string) "N-acetylputrescine acetylhydrolase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acetylsalicylate deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.55"^^xsd:string) "aspirin hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.55"^^xsd:string) "aspirin esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.55"^^xsd:string) "acetylsalicylic acid esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.55"^^xsd:string) "acetylsalicylate O-acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.55"^^xsd:string) Annotation( "RHEA:11755"^^xsd:string) "Catalysis of the reaction: acetylsalicylate + H(2)O = acetate + H(+) + salicylate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.48"^^xsd:string) Annotation( "RHEA:23931"^^xsd:string) "Catalysis of the reaction: N(8)-acetylspermidine + H(2)O = acetate + spermidine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.48"^^xsd:string) "N(8)-acetylspermidine deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.48"^^xsd:string) "N8-acetylspermidine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.48"^^xsd:string) "N-acetylspermidine deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.48"^^xsd:string) "8-N-acetylspermidine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.48"^^xsd:string) "N8-monoacetylspermidine deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.48"^^xsd:string) "N(1)-acetylspermidine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.48"^^xsd:string) "N(8)-acetylspermidine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.48"^^xsd:string) "N(8)-monoacetylspermidine deacetylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetylspermidine deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.48"^^xsd:string) "N8-acetylspermidine deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.48"^^xsd:string) "N1-acetylspermidine amidohydrolase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.10"^^xsd:string) "acyl-CoA synthetase (GDP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.10"^^xsd:string) "acid:CoA ligase (GDP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "acid-CoA ligase (GDP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.10"^^xsd:string) "acyl coenzyme A synthetase (guanosine diphosphate forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.10"^^xsd:string) Annotation( "RHEA:10971"^^xsd:string) "Catalysis of the reaction: a carboxylate + CoA + GTP = acyl-CoA + GDP + H(+) + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.6"^^xsd:string) "cis-aconitate carboxy-lyase (itaconate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.6"^^xsd:string) "cis-aconitic decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.6"^^xsd:string) Annotation( "RHEA:15256"^^xsd:string) "Catalysis of the reaction: cis-aconitate + H(+) = CO(2) + itaconate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.6"^^xsd:string) "cis-aconitate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.6"^^xsd:string) "CAD activity"^^xsd:string) AnnotationAssertion(rdfs:label "aconitate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.3.7"^^xsd:string) "aconitate delta2-delta3-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.7"^^xsd:string) Annotation( "RHEA:17268"^^xsd:string) "Catalysis of the reaction: trans-aconitate = cis-aconitate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.7"^^xsd:string) "aconitate isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aconitate delta-isomerase activity"^^xsd:string) AnnotationAssertion( "aconitate D-isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "actinomycin lactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.39"^^xsd:string) "actinomycin lactonohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.39"^^xsd:string) Annotation( "MetaCyc:ACTINOMYCIN-LACTONASE-RXN"^^xsd:string) "Catalysis of the reaction: actinomycin + H2O = actinomycinic monolactone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acyl-CoA dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.8"^^xsd:string) Annotation( "MetaCyc:ACYL-COA-DEHYDROGENASE-NADP+-RXN"^^xsd:string) "Catalysis of the reaction: acyl-CoA + NADP+ = 2,3-dehydroacyl-CoA + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.8"^^xsd:string) "2-enoyl-CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.8"^^xsd:string) "dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.8"^^xsd:string) "enoyl coenzyme A reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.8"^^xsd:string) "crotonyl coenzyme A reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.8"^^xsd:string) "acyl-CoA:NADP+ 2-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "acyl-CoA thioesterase I activity"^^xsd:string) AnnotationAssertion( "acyl-CoA thioesterase activity"^^xsd:string) AnnotationAssertion( "acyl-CoA thiolesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.20"^^xsd:string) "thioesterase B"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.20"^^xsd:string) Annotation( "MetaCyc:ACYL-COA-HYDROLASE-RXN"^^xsd:string) "Catalysis of the reaction: acyl-CoA + H2O = CoA + a carboxylate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.20"^^xsd:string) "acyl coenzyme A hydrolase activity"^^xsd:string) AnnotationAssertion( "acyl-CoA thioesterase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.20"^^xsd:string) "thioesterase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.20"^^xsd:string) "acyl coenzyme A thioesterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acyl-CoA hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.40"^^xsd:string) "acylagmatine deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.40"^^xsd:string) "benzoylagmatine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.40"^^xsd:string) Annotation( "RHEA:15068"^^xsd:string) "Catalysis of the reaction: N(4)-benzoylagmatine + H(2)O = agmatine + benzoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.40"^^xsd:string) "acylagmatine amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acylagmatine amidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.28"^^xsd:string) "carnitine ester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.28"^^xsd:string) "long-chain acyl-L-carnitine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.28"^^xsd:string) "high activity acylcarnitine hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acylcarnitine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.28"^^xsd:string) "palmitoylcarnitine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.28"^^xsd:string) "O-acylcarnitine acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.28"^^xsd:string) "palmitoyl-L-carnitine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.28"^^xsd:string) "HACH"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.28"^^xsd:string) "palmitoyl carnitine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.28"^^xsd:string) Annotation( "MetaCyc:ACYLCARNITINE-HYDROLASE-RXN"^^xsd:string) "Catalysis of the reaction: O-acylcarnitine + H2O = a fatty acid + L-carnitine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.94"^^xsd:string) "monoacylglycerol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.94"^^xsd:string) "monoacylglycerol kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.94"^^xsd:string) "monoglyceride kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.94"^^xsd:string) Annotation( "MetaCyc:ACYLGLYCEROL-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + acylglycerol = ADP + acyl-sn-glycerol 3-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.94"^^xsd:string) "ATP:acylglycerol 3-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.94"^^xsd:string) "monoglyceride phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.94"^^xsd:string) "MGK"^^xsd:string) AnnotationAssertion(rdfs:label "acylglycerol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.94"^^xsd:string) "sn-2-monoacylglycerol kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.7.1.5"^^xsd:string) "3-acylpyruvate acylhydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acylpyruvate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.5"^^xsd:string) Annotation( "MetaCyc:ACYLPYRUVATE-HYDROLASE-RXN"^^xsd:string) "Catalysis of the reaction: a 3-acylpyruvate + H2O = a carboxylate + pyruvate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.7"^^xsd:string) "adenosine hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "adenosine nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.7"^^xsd:string) "adenosinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.7"^^xsd:string) "adenosine ribohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.7"^^xsd:string) "ANase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.7"^^xsd:string) "N-ribosyladenine ribohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.7"^^xsd:string) Annotation( "MetaCyc:ADENOSINE-NUCLEOSIDASE-RXN"^^xsd:string) "Catalysis of the reaction: adenosine + H2O = D-ribose + adenine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.17"^^xsd:string) "adenosine-phosphate aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.17"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "MetaCyc:ADENOSINE-PHOSPHATE-DEAMINASE-RXN"^^xsd:string) "Catalysis of the reaction: an adenosine-phosphate + H20 = an inosine phosphate + NH3. Catalyzes the deamination of AMP, ADP or ATP."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.17"^^xsd:string) "adenine nucleotide deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.17"^^xsd:string) "adenosine (phosphate) deaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "adenosine-phosphate deaminase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "adenosine-tetraphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.14"^^xsd:string) Annotation( "MetaCyc:ADENOSINE-TETRAPHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: adenosine 5'-tetraphosphate + H2O = ATP + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.14"^^xsd:string) "adenosine-tetraphosphate phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.4"^^xsd:string) "adenosylmethioninase activity"^^xsd:string) AnnotationAssertion( "adenosyl methionine cyclotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.4"^^xsd:string) Annotation( "RHEA:21935"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + homoserine lactone."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.4"^^xsd:string) "S-adenosyl-L-methionine alkyltransferase (cyclizing)"^^xsd:string) AnnotationAssertion(rdfs:label "adenosylmethionine cyclotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.3.1.2"^^xsd:string) Annotation( "RHEA:14648"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + H(2)O = S-methyl-5'-thioadenosine + L-homoserine + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "adenosylmethionine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.1.2"^^xsd:string) "methylmethionine-sulfonium-salt hydrolase activity"^^xsd:string) AnnotationAssertion( "adenosyl methionine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.1.2"^^xsd:string) "S-adenosylmethionine cleaving enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.1.2"^^xsd:string) "adenosylmethionine lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.1.2"^^xsd:string) "S-adenosyl-L-methionine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "adenylylsulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.2.1"^^xsd:string) "adenosine 5-phosphosulfate sulfohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.2.1"^^xsd:string) "adenylylsulfate sulfohydrolase activity"^^xsd:string) AnnotationAssertion( "adenylylsulphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.2.1"^^xsd:string) Annotation( "RHEA:17044"^^xsd:string) "Catalysis of the reaction: 5'-adenylyl sulfate + H(2)O = AMP + 2 H(+) + sulfate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ADP-thymidine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.118"^^xsd:string) "adenosine diphosphate-thymidine phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.118"^^xsd:string) Annotation( "MetaCyc:ADP--THYMIDINE-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: ADP + thymidine = AMP + thymidine 5'-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.118"^^xsd:string) "ADP:dThd phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.118"^^xsd:string) "ADP:thymidine 5'-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.7"^^xsd:string) Annotation( "MetaCyc:ADP-DEAMINASE-RXN"^^xsd:string) "Catalysis of the reaction: ADP + H2O = IDP + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.7"^^xsd:string) "adenosinepyrophosphate deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.7"^^xsd:string) "ADP aminohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ADP deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.7"^^xsd:string) "adenosine diphosphate deaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.28"^^xsd:string) "ADPphosphoglycerate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.28"^^xsd:string) "adenosine diphosphate phosphoglycerate phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ADP-phosphoglycerate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.28"^^xsd:string) Annotation( "RHEA:15864"^^xsd:string) "Catalysis of the reaction: 3-ADP-2-phosphoglycerate + H(2)O = 3-ADP-glycerate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.28"^^xsd:string) "3-(ADP)-2-phosphoglycerate phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "adenosine diphosphoribose pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.13"^^xsd:string) "ADP-ribose ribophosphohydrolase activity"^^xsd:string) AnnotationAssertion( "ADP-ribose phosphohydrolase activity"^^xsd:string) AnnotationAssertion( "ADPR-PPase activity"^^xsd:string) AnnotationAssertion( "ADP-ribose pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.13"^^xsd:string) "ADPribose diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.13"^^xsd:string) "ADPribose pyrophosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ADP-ribose diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.13"^^xsd:string) Annotation( "MetaCyc:ADP-RIBOSE-PYROPHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.12"^^xsd:string) "agmatine iminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.12"^^xsd:string) "agmatine amidinohydrolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.12"^^xsd:string) Annotation( "MetaCyc:AGMATINE-DEIMINASE-RXN"^^xsd:string) "Catalysis of the reaction: agmatine + H2O = N-carbamoylputrescine + NH3."^^xsd:string) AnnotationAssertion(rdfs:label "agmatine deiminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.3.10"^^xsd:string) "ATP:agmatine N4-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.10"^^xsd:string) Annotation( "RHEA:15956"^^xsd:string) "Catalysis of the reaction: agmatine + ATP = N(4)-phosphoagmatine + ADP + 3 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.10"^^xsd:string) "phosphagen phosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.10"^^xsd:string) "ATP:agmatine 4-N-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "agmatine kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.64"^^xsd:string) "p-coumaroyl-CoA-agmatine N-p-coumaroyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.64"^^xsd:string) "agmatine coumaroyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "agmatine N4-coumaroyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.64"^^xsd:string) "4-coumaroyl-CoA:agmatine N4-coumaroyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.64"^^xsd:string) "4-coumaroyl-CoA:agmatine 4-N-coumaroyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.64"^^xsd:string) Annotation( "RHEA:13408"^^xsd:string) "Catalysis of the reaction: 4-coumaroyl-CoA + agmatine = N-(4-guanidiniumylbutyl)-4-hydroxycinnamamide + CoA + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.12"^^xsd:string) Annotation( "MetaCyc:ALANINE--OXO-ACID-AMINOTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: L-alanine + a 2-oxo acid = pyruvate + an L-amino acid."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.12"^^xsd:string) "alanine-keto acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.12"^^xsd:string) "L-alanine-alpha-keto acid aminotransferase activity"^^xsd:string) AnnotationAssertion( "alanine-oxo-acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.12"^^xsd:string) "leucine-alanine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.12"^^xsd:string) "alanine-oxo acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.12"^^xsd:string) "alanine--oxo-acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.12"^^xsd:string) "L-alanine:2-oxo-acid aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alanine-oxo-acid transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.17"^^xsd:string) "alanopine: NAD oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.17"^^xsd:string) "alanopine[meso-N-(1-carboxyethyl)-alanine]dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.17"^^xsd:string) Annotation( "RHEA:17592"^^xsd:string) "Catalysis of the reaction: 2,2'-iminodipropanoate + H(2)O + NAD(+) = L-alanine + H(+) + NADH + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.17"^^xsd:string) "ALPDH"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.17"^^xsd:string) "alanopine:NAD oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.17"^^xsd:string) "2,2'-iminodipropanoate:NAD+ oxidoreductase (L-alanine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.17"^^xsd:string) "ADH"^^xsd:string) AnnotationAssertion(rdfs:label "alanopine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.17"^^xsd:string) "meso-N-(1-carboxyethyl)-alanine:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.2.11"^^xsd:string) "alanyl phosphatidylglycerol synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.11"^^xsd:string) "L-alanyl-tRNA:phosphatidylglycerol alanyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.11"^^xsd:string) Annotation( "MetaCyc:ALANYLPHOSPHATIDYLGLYCEROL-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: L-alanyl-tRNA + phosphatidylglycerol = tRNA + 3-O-L-alanyl-1-O-phosphatidylglycerol."^^xsd:string) AnnotationAssertion(rdfs:label "alanylphosphatidylglycerol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.11"^^xsd:string) "O-alanylphosphatidylglycerol synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.32"^^xsd:string) "albendazole sulfoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.32"^^xsd:string) "albendazole,NADPH:oxygen oxidoreductase (sulfoxide-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.32"^^xsd:string) "albendazole oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.32"^^xsd:string) Annotation( "RHEA:10799"^^xsd:string) "Catalysis of the reaction: albendazole + H(+) + NADPH + O(2) = albendazole S-oxide + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(rdfs:label "albendazole monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.13"^^xsd:string) "AOX activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.13"^^xsd:string) "alcohol:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alcohol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.13"^^xsd:string) Annotation( "MetaCyc:ALCOHOL-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: a primary alcohol + O2 = an aldehyde + H2O2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.13"^^xsd:string) "ethanol oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.121"^^xsd:string) "aldose dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aldose 1-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.121"^^xsd:string) Annotation( "MetaCyc:ALDOSE-1-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: D-aldose + NAD+ = D-aldonolactone + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.121"^^xsd:string) "D-aldose:NAD+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.121"^^xsd:string) "dehydrogenase, D-aldohexose"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.200"^^xsd:string) "A6PR"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.200"^^xsd:string) "aldose 6-phosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.200"^^xsd:string) "aldose-6-P reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aldose-6-phosphate reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.200"^^xsd:string) "aldose-6-phosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.200"^^xsd:string) "NADP-dependent aldose 6-phosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.200"^^xsd:string) "alditol 6-phosphate:NADP 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.200"^^xsd:string) Annotation( "RHEA:20040"^^xsd:string) "Catalysis of the reaction: D-glucitol 6-phosphate + NADP(+) = D-glucose 6-phosphate + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.200"^^xsd:string) "D-aldose-6-phosphate:NADP+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.200"^^xsd:string) "NADP-dependent D-sorbitol-6-phosphate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "aldose b-D-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.162"^^xsd:string) Annotation( "MetaCyc:ALDOSE-BETA-FRUCTOSYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: alpha-D-aldosyl1 beta-D-fructoside + D-aldose2 = D-aldose1 + alpha-D-aldosyl2 beta-D-fructoside."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.162"^^xsd:string) "alpha-D-aldosyl-beta-D-fructoside:aldose 1-beta-D-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aldose beta-D-fructosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alginate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.33"^^xsd:string) "GDP-D-mannuronate:alginate D-mannuronyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.33"^^xsd:string) "mannuronosyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.33"^^xsd:string) Annotation( "MetaCyc:ALGINATE-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: GDP-D-mannuronate + alginate(n) = GDP + alginate(n+1)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.103"^^xsd:string) "uridine diphosphoglucose-alizarin glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alizarin 2-beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.103"^^xsd:string) "UDP-glucose:1,2-dihydroxy-9,10-anthraquinone 2-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.103"^^xsd:string) "UDPglucose:1,2-dihydroxy-9,10-anthraquinone 2-O-beta-D-glucosyl-transferase activity"^^xsd:string) AnnotationAssertion( "alizarin 2-b-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.103"^^xsd:string) Annotation( "RHEA:20680"^^xsd:string) "Catalysis of the reaction: alizarin + UDP-D-glucose = 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone + H(+) + UDP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alkan-1-ol dehydrogenase (acceptor) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.20"^^xsd:string) "polyethylene glycol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.20"^^xsd:string) Annotation( "MetaCyc:ALKAN-1-OL-DEHYDROGENASE-ACCEPTOR-RXN"^^xsd:string) "Catalysis of the reaction: primary alcohol + acceptor = aldehyde + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.20"^^xsd:string) "alkan-1-ol:(acceptor) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.20"^^xsd:string) "alkan-1-ol:acceptor oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.14.3"^^xsd:string) "aldehyde monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alkanal monooxygenase (FMN-linked) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.3"^^xsd:string) "vibrio fischeri luciferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.3"^^xsd:string) "alkanal,reduced-FMN:oxygen oxidoreductase (1-hydroxylating, luminescing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.3"^^xsd:string) Annotation( "MetaCyc:ALKANAL-MONOOXYGENASE-FMN-LINKED-RXN"^^xsd:string) "Catalysis of the reaction: R-CHO + reduced FMN + O2 = R-COOH + FMN + H2O + light."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.3"^^xsd:string) "bacterial luciferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.59"^^xsd:string) "1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.59"^^xsd:string) "alkylacetylglycerophosphate phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alkylacetylglycerophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.59"^^xsd:string) "1-alkyl-2-acetyl-sn-glycero-3-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.59"^^xsd:string) Annotation( "RHEA:18224"^^xsd:string) "Catalysis of the reaction: 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + H(2)O = 2-acetyl-1-alkyl-sn-glycerol + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.39"^^xsd:string) Annotation( "RHEA:20084"^^xsd:string) "Catalysis of the reaction: N-methylhexanamide + H(2)O = hexanoate + methylammonium."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.39"^^xsd:string) "N-methylhexanamide amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alkylamidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.93"^^xsd:string) "ATP:1-O-alkyl-sn-glycerol 3-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.93"^^xsd:string) Annotation( "RHEA:16940"^^xsd:string) "Catalysis of the reaction: 1-alkyl-sn-glycerol + ATP = 1-alkyl-sn-glycerol 3-phosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.93"^^xsd:string) "alkylglycerol phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.93"^^xsd:string) "1-alkylglycerol kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.93"^^xsd:string) "ATP-alkylglycerol phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.93"^^xsd:string) "ATP:1-alkyl-sn-glycerol phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alkylglycerol kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.84"^^xsd:string) "alkyldihydroxyacetone kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.84"^^xsd:string) "ATP:O-alkylglycerone phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alkylglycerone kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.84"^^xsd:string) "alkyldihydroxyacetone kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.84"^^xsd:string) Annotation( "RHEA:23091"^^xsd:string) "Catalysis of the reaction: O-alkylglycerone + ATP = O-alkylglycerone phosphate + ADP + 2 H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.8.1.1"^^xsd:string) "alkyl-halide halidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.1"^^xsd:string) "halogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.1"^^xsd:string) "haloalkane halidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.8.1.1"^^xsd:string) Annotation( "RHEA:13768"^^xsd:string) "Catalysis of the reaction: bromochloromethane + H(2)O = bromide + chloride + formaldehyde + 2 H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "alkylhalidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "allantoate deiminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.9"^^xsd:string) "allantoate amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.9"^^xsd:string) "allantoate amidinohydrolase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.9"^^xsd:string) Annotation( "MetaCyc:ALLANTOATE-DEIMINASE-RXN"^^xsd:string) "Catalysis of the reaction: allantoate + H2O + H+ = CO2 + NH3 + ureidoglycine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.99.3"^^xsd:string) Annotation( "RHEA:10807"^^xsd:string) "Catalysis of the reaction: (S)-(+)-allantoin = (R)-(-)-allantoin."^^xsd:string) AnnotationAssertion(rdfs:label "allantoin racemase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.4"^^xsd:string) "alkylcysteine sulfoxide lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.4"^^xsd:string) "L-cysteine sulfoxide lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.4"^^xsd:string) "cysteine sulfoxide lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.4"^^xsd:string) "alliinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.4"^^xsd:string) Annotation( "MetaCyc:ALLIIN-LYASE-RXN"^^xsd:string) "Catalysis of the reaction: an S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2-aminoacrylate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.4"^^xsd:string) "S-alkyl-L-cysteine S-oxide alkyl-sulfenate-lyase (2-aminoacrylate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.4"^^xsd:string) "S-alkylcysteine sulfoxide lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.4"^^xsd:string) "cysteine sulphoxide lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alliin lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.4"^^xsd:string) "alliin alkyl-sulfenate-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.54"^^xsd:string) Annotation( "RHEA:12171"^^xsd:string) "Catalysis of the reaction: allyl alcohol + NADP(+) = acrolein + H(+) + NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "allyl-alcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.54"^^xsd:string) "allyl-alcohol:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.64"^^xsd:string) Annotation( "MetaCyc:ALPHAALPHA-TREHALOSE-PHOSPHORYLASE-RXN"^^xsd:string) "Catalysis of the reaction: alpha,alpha-trehalose + phosphate = D-glucose + beta-D-glucose 1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.64"^^xsd:string) "trehalose phosphorylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.64"^^xsd:string) "alpha,alpha-trehalose:phosphate beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha,alpha-trehalose phosphorylase activity"^^xsd:string) AnnotationAssertion( "a,a-trehalose phosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "1,3-alpha-glucan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.183"^^xsd:string) Annotation( "MetaCyc:ALPHA-13-GLUCAN-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: UDP-glucose + [alpha-D-glucosyl-(1,3)]n = UDP + [alpha-D-glucosyl-(1,3)]n+1."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-1,3-glucan synthase activity"^^xsd:string) AnnotationAssertion( "a-1,3-glucan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.183"^^xsd:string) "UDP-glucose:alpha-D-(1->3)-glucan 3-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.183"^^xsd:string) "1,3-alpha-D-glucan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.183"^^xsd:string) "uridine diphosphoglucose-1,3-alpha-glucan glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.183"^^xsd:string) "UDPglucose:alpha-D-(1->3)-glucan 3-alpha-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.43"^^xsd:string) "alpha-amino-acid ester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.43"^^xsd:string) "alpha-amino-acid-ester aminoacylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.43"^^xsd:string) Annotation( "MetaCyc:ALPHA-AMINO-ACID-ESTERASE-RXN"^^xsd:string) "Catalysis of the reaction: an alpha-amino acid ester + H2O = an alpha-amino acid + an alcohol."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.43"^^xsd:string) "alpha-amino acid ester hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-amino-acid esterase activity"^^xsd:string) AnnotationAssertion( "a-amino-acid esterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.47"^^xsd:string) Annotation( "MetaCyc:ALPHA-SANTONIN-12-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: 1,2-dihydrosantonin + NAD(P)+ = alpha-santonin + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-santonin 1,2-reductase activity"^^xsd:string) AnnotationAssertion( "a-santonin 1,2-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.47"^^xsd:string) "1,2-dihydrosantonin:NAD(P)+ 1,2-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.14"^^xsd:string) "N-amidino-L-aspartate amidinohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.14"^^xsd:string) Annotation( "RHEA:14852"^^xsd:string) "Catalysis of the reaction: N-amidino-L-aspartate + H(2)O = L-aspartate + urea."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.14"^^xsd:string) "amidinoaspartic amidinohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "amidinoaspartase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "amino-acid racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.10"^^xsd:string) Annotation( "MetaCyc:AMINO-ACID-RACEMASE-RXN"^^xsd:string) "Catalysis of the reaction: an L-amino acid = a D-amino acid."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.10"^^xsd:string) "L-amino acid racemase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.24"^^xsd:string) "aminobenzoate carboxy-lyase (aniline-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.24"^^xsd:string) "aminobenzoate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.24"^^xsd:string) Annotation( "MetaCyc:AMINOBENZOATE-DECARBOXYLASE-RXN"^^xsd:string) "Catalysis of the reaction: 4(or 2)-aminobenzoate = aniline + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "aminobenzoate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.82"^^xsd:string) "6'-aminoglycoside-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.82"^^xsd:string) "acetyl-CoA:kanamycin-B N6'-acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aminoglycoside 6'-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.82"^^xsd:string) "aminoglycoside-6-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion( "aminoglycoside N6'-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.82"^^xsd:string) Annotation( "RHEA:16452"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + kanamycin B = N(6')-acetylkanamycin B + CoA + H(+). This is acetylation of the 6'-amino group of the 6-deoxy-6-aminoglucose ring."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.82"^^xsd:string) "AAC(6') activity"^^xsd:string) AnnotationAssertion( "kanamycin 6'-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.82"^^xsd:string) "aminoglycoside-6'-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.8"^^xsd:string) "4-aminoimidazole hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.8"^^xsd:string) "4-aminoimidazole aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.8"^^xsd:string) Annotation( "MetaCyc:AMINOIMIDAZOLASE-RXN"^^xsd:string) "Catalysis of the reaction: 4-aminoimidazole + H2O = unidentified product + NH3."^^xsd:string) AnnotationAssertion(rdfs:label "aminoimidazolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "aminolevulinate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aminolevulinate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.43"^^xsd:string) "dioxovalerate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.43"^^xsd:string) "5-aminolevulinic acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.43"^^xsd:string) "L-alanine:4,5-dioxovaleric acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.43"^^xsd:string) "aminolevulinic acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.43"^^xsd:string) "4,5-dioxovaleric transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.43"^^xsd:string) "L-alanine-4,5-dioxovalerate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.43"^^xsd:string) "alanine:4,5-dioxovalerate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.43"^^xsd:string) "alanine-dioxovalerate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.43"^^xsd:string) "4,5-dioxovalerate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.43"^^xsd:string) "gamma,delta-dioxovaleric acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.43"^^xsd:string) "4,5-dioxovaleric acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.43"^^xsd:string) "DOVA transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.43"^^xsd:string) "gamma,delta-dioxovalerate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.43"^^xsd:string) "5-aminolevulinate:pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.43"^^xsd:string) "L-alanine:dioxovalerate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.43"^^xsd:string) "4,5-dioxovaleric acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.43"^^xsd:string) Annotation( "RHEA:12483"^^xsd:string) "Catalysis of the reaction: 5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.43"^^xsd:string) "alanine-gamma,delta-dioxovalerate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.3.8"^^xsd:string) "phosphoramidate-ADP-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.8"^^xsd:string) "ATP:ammonia phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.8"^^xsd:string) "phosphoramidate-adenosine diphosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.8"^^xsd:string) Annotation( "RHEA:11027"^^xsd:string) "Catalysis of the reaction: ATP + NH(4)(+) = ADP + 3 H(+) + phosphoramidate."^^xsd:string) AnnotationAssertion(rdfs:label "ammonia kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.114"^^xsd:string) "thymidine phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.114"^^xsd:string) "adenylic acid:deoxythymidine 5'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.114"^^xsd:string) "AMP:thymidine 5'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "AMP-thymidine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.114"^^xsd:string) "AMP:dThd kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.114"^^xsd:string) Annotation( "MetaCyc:AMP--THYMIDINE-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: AMP + thymidine = adenosine + thymidine 5'-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.114"^^xsd:string) "AMP:deoxythymidine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.114"^^xsd:string) "adenylate-nucleoside phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.114"^^xsd:string) "AMP:deoxythymidine 5'-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.117"^^xsd:string) "amygdalin glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.117"^^xsd:string) "amygdalin hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.117"^^xsd:string) Annotation( "RHEA:14180"^^xsd:string) "Catalysis of the reaction: (R)-amygdalin + H(2)O = (R)-prunasin + D-glucose."^^xsd:string) AnnotationAssertion( "(R)-amygdalin beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.117"^^xsd:string) "amygdalin beta-D-glucohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "amygdalin beta-glucosidase activity"^^xsd:string) AnnotationAssertion( "amygdalin b-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.117"^^xsd:string) "amygdalinase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.4"^^xsd:string) "sucrose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.4"^^xsd:string) "sucrose-1,4-alpha-glucan glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.4"^^xsd:string) Annotation( "MetaCyc:AMYLOSUCRASE-RXN"^^xsd:string) "Catalysis of the reaction: sucrose + 1,4-alpha-D-glucosyl(n) = D-fructose + 1,4-alpha-D-glucosyl(n+1)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.4"^^xsd:string) "sucrose-glucan glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "amylosucrase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.38"^^xsd:string) "ATC oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.38"^^xsd:string) "anhydrotetracycline,NADPH:oxygen oxidoreductase (6-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.38"^^xsd:string) "anhydrotetracycline oxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "anhydrotetracycline monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.38"^^xsd:string) Annotation( "RHEA:11979"^^xsd:string) "Catalysis of the reaction: anhydrotetracycline + H(+) + NADPH + O(2) = 12-dehydrotetracycline + H(2)O + NADP(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ATP:anthranilate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.55"^^xsd:string) Annotation( "RHEA:22415"^^xsd:string) "Catalysis of the reaction: anthranilate + ATP = N-adenylylanthranilate + diphosphate + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "anthranilate adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.55"^^xsd:string) "anthranilic acid adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.55"^^xsd:string) "ATP:anthranilate N-adenylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "anthranilate N-benzoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.144"^^xsd:string) Annotation( "RHEA:21603"^^xsd:string) "Catalysis of the reaction: anthranilate + benzoyl-CoA = N-benzoylanthranilate + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.144"^^xsd:string) "benzoyl-CoA:anthranilate N-benzoyltransferase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.113"^^xsd:string) "malonyl-CoA:anthranilate N-malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.113"^^xsd:string) Annotation( "RHEA:17560"^^xsd:string) "Catalysis of the reaction: anthranilate + malonyl-CoA = N-malonylanthranilate + CoA."^^xsd:string) AnnotationAssertion(rdfs:label "anthranilate N-malonyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.114"^^xsd:string) "D-apiitol:NAD+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "apiose 1-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.114"^^xsd:string) "D-apiose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.114"^^xsd:string) "D-apiitol reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.114"^^xsd:string) Annotation( "RHEA:15304"^^xsd:string) "Catalysis of the reaction: D-apiitol + NAD(+) = D-apiose + H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arabinonate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.5"^^xsd:string) "D-arabinonate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.5"^^xsd:string) "D-arabinonate hydro-lyase (2-dehydro-3-deoxy-D-arabinonate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.5"^^xsd:string) Annotation( "RHEA:21839"^^xsd:string) "Catalysis of the reaction: D-arabinonate = 2-dehydro-3-deoxy-D-arabinonate + H(2)O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.15"^^xsd:string) "arachidonoyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.15"^^xsd:string) Annotation( "RHEA:19716"^^xsd:string) "Catalysis of the reaction: arachidonate + ATP + CoA = AMP + arachidonoyl-CoA + diphosphate + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "arachidonate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.15"^^xsd:string) "arachidonate:CoA ligase (AMP-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arachidonate 8(R)-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.40"^^xsd:string) "arachidonate:oxygen 8-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.40"^^xsd:string) "8(R)-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.40"^^xsd:string) "8-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:lb"^^xsd:string) "arachidonate 8-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.40"^^xsd:string) Annotation( "RHEA:14988"^^xsd:string) "Catalysis of the reaction: arachidonate + O(2) = (5Z,8R,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arginine 2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.1"^^xsd:string) "arginine decarboxy-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.1"^^xsd:string) "arginine oxygenase (decarboxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.1"^^xsd:string) "arginine monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.1"^^xsd:string) Annotation( "RHEA:10551"^^xsd:string) "Catalysis of the reaction: L-arginine + O(2) = 4-guanidinobutanamide + CO(2) + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.1"^^xsd:string) "L-arginine:oxygen 2-oxidoreductase (decarboxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arginine racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.9"^^xsd:string) Annotation( "MetaCyc:ARGININE-RACEMASE-RXN"^^xsd:string) "Catalysis of the reaction: L-arginine = D-arginine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.13"^^xsd:string) "AAA-2"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.13"^^xsd:string) "aryl-acylamide amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aryl-acylamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.13"^^xsd:string) "AAA-1"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.13"^^xsd:string) "pseudocholinesterase (associated with arylacylamidase)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.13"^^xsd:string) Annotation( "RHEA:20300"^^xsd:string) "Catalysis of the reaction: anilide + H(2)O = a carboxylate + aniline + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.13"^^xsd:string) "brain acetylcholinesterase (is associated with AAA-2)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.91"^^xsd:string) "aryl alcohol dehydrogenase (nicotinamide adenine dinucleotide phosphate)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.91"^^xsd:string) "NADPH-linked benzaldehyde reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aryl-alcohol dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.91"^^xsd:string) "aryl-alcohol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.91"^^xsd:string) Annotation( "MetaCyc:ARYL-ALCOHOL-DEHYDROGENASE-NADP+-RXN"^^xsd:string) "Catalysis of the reaction: an aromatic alcohol + NADP+ = an aromatic aldehyde + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.7"^^xsd:string) Annotation( "MetaCyc:ARYL-ALCOHOL-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: an aromatic primary alcohol + O2 = an aromatic aldehyde + H2O2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.7"^^xsd:string) "aryl alcohol oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aryl-alcohol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.7"^^xsd:string) "aryl-alcohol:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.7"^^xsd:string) "arom. alcohol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.7"^^xsd:string) "veratryl alcohol oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.30"^^xsd:string) Annotation( "MetaCyc:ARYL-ALDEHYDE-DEHYDROGENASE-NADP+-RXN"^^xsd:string) "Catalysis of the reaction: an aromatic aldehyde + NADP+ + AMP + diphosphate + H2O = an aromatic acid + NADPH + ATP."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.30"^^xsd:string) "aromatic acid reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aryl-aldehyde dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.30"^^xsd:string) "aryl-aldehyde:NADP+ oxidoreductase (ATP-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.71"^^xsd:string) "UDPglucose:arylamine N-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.71"^^xsd:string) "uridine diphosphoglucose-arylamine glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.71"^^xsd:string) "UDP glucose-arylamine glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.71"^^xsd:string) Annotation( "MetaCyc:ARYLAMINE-GLUCOSYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: UDP-glucose + an arylamine = UDP + an N-D-glucosylarylamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.71"^^xsd:string) "UDP-glucose:arylamine N-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arylamine glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.3"^^xsd:string) Annotation( "MetaCyc:ARYLAMINE-SULFOTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.3"^^xsd:string) "amine N-sulfotransferase activity"^^xsd:string) AnnotationAssertion( "arylamine sulfotransferase activity"^^xsd:string) AnnotationAssertion( "amine sulphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "amine sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.3"^^xsd:string) "3'-phosphoadenylyl-sulfate:amine N-sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.22"^^xsd:string) "arylsulfotransferase"^^xsd:string) AnnotationAssertion(rdfs:label "arylsulfate sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.22"^^xsd:string) "ASST"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.22"^^xsd:string) Annotation( "MetaCyc:ARYLSULFATE-SULFOTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: an aryl sulfate + a phenol = a phenol + an aryl sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.22"^^xsd:string) "arylsulfate:phenol sulfotransferase activity"^^xsd:string) AnnotationAssertion( "arylsulphate sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.22"^^xsd:string) "arylsulfate-phenol sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.12"^^xsd:string) "aspartic omega-decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.12"^^xsd:string) "cysteine sulfinic desulfinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.12"^^xsd:string) "aminomalonic decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.12"^^xsd:string) "L-cysteine sulfinate acid desulfinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aspartate 4-decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.12"^^xsd:string) "aspartic beta-decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.12"^^xsd:string) "L-aspartate beta-decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.12"^^xsd:string) "aspartate omega-decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.12"^^xsd:string) "L-aspartate 4-carboxy-lyase (L-alanine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.12"^^xsd:string) Annotation( "MetaCyc:ASPARTATE-4-DECARBOXYLASE-RXN"^^xsd:string) "Catalysis of the reaction: L-aspartate = L-alanine + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.12"^^xsd:string) "L-aspartate 4-carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.12"^^xsd:string) "desulfinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.12"^^xsd:string) "aspartate beta-decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aspartate racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.13"^^xsd:string) "D-aspartate racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.13"^^xsd:string) Annotation( "RHEA:14976"^^xsd:string) "Catalysis of the reaction: L-aspartate = D-aspartate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.2.7"^^xsd:string) "L-asparagine:hydroxylamine gamma-aspartyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.7"^^xsd:string) "aspartotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.7"^^xsd:string) Annotation( "RHEA:11255"^^xsd:string) "Catalysis of the reaction: L-asparagine + H(+) + hydroxylamine = beta-L-aspartylhydroxamate + NH(4)(+)."^^xsd:string) AnnotationAssertion(rdfs:label "aspartyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.7"^^xsd:string) "beta-aspartyl transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.35"^^xsd:string) "dimethylallyl pyrophosphate:aspulvinone dimethylallyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.35"^^xsd:string) Annotation( "RHEA:13812"^^xsd:string) "Catalysis of the reaction: aspulvinone E + 2 dimethylallyl diphosphate = aspulvinone H + 2 diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.35"^^xsd:string) "dimethylallyl-diphosphate:aspulvinone-E dimethylallyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aspulvinone dimethylallyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.18"^^xsd:string) "ATP aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.18"^^xsd:string) Annotation( "MetaCyc:ATP-DEAMINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ITP + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.18"^^xsd:string) "adenosine triphosphate deaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ATP deaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.8"^^xsd:string) "adenosine triphosphate pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.8"^^xsd:string) "ATP diphosphohydrolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.8"^^xsd:string) "ATP diphosphohydrolase (diphosphate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "ATP diphosphatase activity"^^xsd:string) AnnotationAssertion( "ATP pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.8"^^xsd:string) Annotation( "MetaCyc:ATP-PYROPHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + H2O = AMP + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "barbiturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.1"^^xsd:string) "barbiturate amidohydrolase (3-oxo-3-ureidopropanoate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.1"^^xsd:string) Annotation( "MetaCyc:BARBITURASE-RXN"^^xsd:string) "Catalysis of the reaction: barbiturate + H2O = malonate + urea."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.38"^^xsd:string) "diphenylethanone benzaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.38"^^xsd:string) "2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2- activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.38"^^xsd:string) Annotation( "RHEA:21463"^^xsd:string) "Catalysis of the reaction: benzoin = 2 benzaldehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.38"^^xsd:string) "benzaldehyde lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.38"^^xsd:string) "2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.38"^^xsd:string) "2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase (benzaldehyde-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "benzoin aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "beta-ARK 2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "beta-adrenoceptor kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "beta-AR kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "beta-ARK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "beta-adrenoceptor kinase 2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "beta-receptor kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "[b-adrenergic-receptor] kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "beta-adrenoceptor kinase 1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "beta-adrenergic-receptor kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "ADRBK1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "GRK2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "betaARK1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "beta2ARK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "adrenergic receptor kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "ATP:beta-adrenergic-receptor phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "beta-adrenergic receptor-specific kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "STK15"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "GRK3"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) Annotation( "MetaCyc:BETA-ADRENERGIC-RECEPTOR-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + beta-adrenergic receptor = ADP + phospho-beta-adrenergic receptor."^^xsd:string) AnnotationAssertion(rdfs:label "beta-adrenergic receptor kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "beta-ARK 1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "beta-adrenergic-receptor kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.15"^^xsd:string) "BARK1"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "b-alanopine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.26"^^xsd:string) "N-(D-1-carboxyethyl)-beta-alanine:NAD+ oxidoreductase (beta-alanine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.26"^^xsd:string) Annotation( "RHEA:21687"^^xsd:string) "Catalysis of the reaction: (R)-beta-alanopine + H(2)O + NAD(+) = beta-alanine + H(+) + NADH + pyruvate."^^xsd:string) AnnotationAssertion(rdfs:label "beta-alanopine dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-alanyl-CoA ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.6"^^xsd:string) Annotation( "MetaCyc:BETA-ALANYL-COA-AMMONIA-LYASE-RXN"^^xsd:string) "Catalysis of the reaction: beta-alanyl-CoA = acryloyl-CoA + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.6"^^xsd:string) "beta-alanyl coenzyme A ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.6"^^xsd:string) "beta-alanyl-CoA ammonia-lyase (acryloyl-CoA-forming)"^^xsd:string) AnnotationAssertion( "b-alanyl-CoA ammonia-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "b-diketone hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.7"^^xsd:string) Annotation( "RHEA:11911"^^xsd:string) "Catalysis of the reaction: H(2)O + nonane-4,6-dione = butanoate + H(+) + pentan-2-one."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.7"^^xsd:string) "nonane-4,6-dione acylhydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-diketone hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.7"^^xsd:string) "oxidized PVA hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.85"^^xsd:string) "beta-D-glucoside kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.85"^^xsd:string) "ATP:cellobiose 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-glucoside kinase activity"^^xsd:string) AnnotationAssertion( "b-glucoside kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.85"^^xsd:string) Annotation( "MetaCyc:BETA-GLUCOSIDE-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + cellobiose = ADP + 6-phospho-beta-D-glucosyl-(1,4)-D-glucose."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.88"^^xsd:string) "beta-L-arabinoside arabinohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-L-arabinosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.88"^^xsd:string) Annotation( "MetaCyc:BETA-L-ARABINOSIDASE-RXN"^^xsd:string) "Catalysis of the reaction: H2O + a beta-L-arabinoside = L-arabinose + an alcohol."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.88"^^xsd:string) "vicianosidase activity"^^xsd:string) AnnotationAssertion( "b-L-arabinosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.3.3"^^xsd:string) Annotation( "RHEA:21739"^^xsd:string) "Catalysis of the reaction: (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate."^^xsd:string) AnnotationAssertion( "b-lysine 5,6-aminomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.3.3"^^xsd:string) "(3S)-3,6-diaminohexanoate 5,6-aminomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.3.3"^^xsd:string) "L-beta-lysine 5,6-aminomutase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-lysine 5,6-aminomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.3.3"^^xsd:string) "beta-lysine mutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "b-nitroacrylate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.16"^^xsd:string) Annotation( "RHEA:23895"^^xsd:string) "Catalysis of the reaction: 3-nitropropanoate + NADP(+) = 3-nitroacrylate + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.16"^^xsd:string) "3-nitropropanoate:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-nitroacrylate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.14"^^xsd:string) Annotation( "MetaCyc:BILE-SALT-SULFOTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + taurolithocholate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.14"^^xsd:string) "3'-phosphoadenylyl-sulfate:glycolithocholate sulfotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "bile-salt sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.14"^^xsd:string) "bile acid sulfotransferase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.14"^^xsd:string) "glycolithocholate sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.14"^^xsd:string) "BAST I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.14"^^xsd:string) "bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.14"^^xsd:string) "bile salt:3'phosphoadenosine-5'-phosphosulfate:sulfotransferase activity"^^xsd:string) AnnotationAssertion( "bile-salt sulphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.3.5"^^xsd:string) "bilirubin oxidase M-1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.5"^^xsd:string) Annotation( "RHEA:20983"^^xsd:string) "Catalysis of the reaction: 2 bilirubin + O(2) = 2 biliverdin + 2 H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.5"^^xsd:string) "bilirubin:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "bilirubin oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.46"^^xsd:string) Annotation( "RHEA:12820"^^xsd:string) "Catalysis of the reaction: dihydrobiochanin A + NADP(+) = biochanin A + H(+) + NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "biochanin-A reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.46"^^xsd:string) "dihydrobiochanin-A:NADP+ delta2-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.11"^^xsd:string) "biotin:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.11"^^xsd:string) Annotation( "MetaCyc:BIOTIN--COA-LIGASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + biotin + CoA = AMP + diphosphate + biotinyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.11"^^xsd:string) "biotinyl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.11"^^xsd:string) "biotin CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.11"^^xsd:string) "biotinyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "biotin-CoA ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.12"^^xsd:string) Annotation( "MetaCyc:BIOTINIDASE-RXN"^^xsd:string) "Catalysis of the reaction: biotin amide + H2O = biotin + NH3."^^xsd:string) AnnotationAssertion(rdfs:label "biotinidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.12"^^xsd:string) "amidohydrolase biotinidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.12"^^xsd:string) "biotin-amide amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.60"^^xsd:string) Annotation( "RHEA:15532"^^xsd:string) "Catalysis of the reaction: bis(2-ethylhexyl)phthalate + H(2)O = 2-ethylhexan-1-ol + 2-ethylhexyl phthalate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.60"^^xsd:string) "DEHP esterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "bis(2-ethylhexyl)phthalate esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.60"^^xsd:string) "bis(2-ethylhexyl)phthalate acylhydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.29"^^xsd:string) Annotation( "RHEA:13896"^^xsd:string) "Catalysis of the reaction: P(1),P(3)-bis(5'-adenosyl) triphosphate + H(2)O = ADP + AMP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.29"^^xsd:string) "AP(3)A hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.29"^^xsd:string) "diadenosine 5',5'''-P(1),P(3)-triphosphate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.29"^^xsd:string) "AP3Aase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.29"^^xsd:string) "P1,P3-bis(5'-adenosyl)-triphosphate adenylohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.29"^^xsd:string) "AP3A hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.29"^^xsd:string) "dinucleosidetriphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.29"^^xsd:string) "1-P,3-P-bis(5'-adenosyl)-triphosphate adenylohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "bis(5'-adenosyl)-triphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.29"^^xsd:string) "diadenosine 5,5-P1,P3-triphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.29"^^xsd:string) "diadenosine 5',5'''-P1,P3-triphosphate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.29"^^xsd:string) "AP(3)Aase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.23"^^xsd:string) "blasticidin-S aminohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "blasticidin-S deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.23"^^xsd:string) Annotation( "MetaCyc:BLASTICIDIN-S-DEAMINASE-RXN"^^xsd:string) "Catalysis of the reaction: blasticidin S + H2O = deaminohydroxyblasticidin S + NH3."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.12.6"^^xsd:string) "luciferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.6"^^xsd:string) "luciferase (Cypridina luciferin)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.6"^^xsd:string) "Cypridina-luciferin:oxygen 2-oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.6"^^xsd:string) "Cypridina luciferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "Cypridina-luciferin 2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.6"^^xsd:string) Annotation( "MetaCyc:CYPRIDINA-LUCIFERIN-2-MONOOXYGENASE-RXN"^^xsd:string) "Catalysis of the reaction: Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 + light."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.6"^^xsd:string) "Cypridina-type luciferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "galactitol 2-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.16"^^xsd:string) Annotation( "RHEA:20688"^^xsd:string) "Catalysis of the reaction: galactitol + NAD(+) = D-tagatose + H(+) + NADH."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.26"^^xsd:string) "polygalactolipase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactolipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.26"^^xsd:string) "galactolipid lipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.26"^^xsd:string) "galactolipid acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.26"^^xsd:string) Annotation( "MetaCyc:GALACTOLIPASE-RXN"^^xsd:string) "Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O = 3-beta-D-galactosyl-sn-glycerol + 2 carboxylates."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.26"^^xsd:string) "1,2-diacyl-3-beta-D-galactosyl-sn-glycerol acylhydrolase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.3.6"^^xsd:string) "ATP:hypotaurocyamine N-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.6"^^xsd:string) Annotation( "RHEA:24011"^^xsd:string) "Catalysis of the reaction: ATP + hypotaurocyamine = N(omega)-phosphohypotaurocyamine + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "hypotaurocyamine kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "imidazole N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.2"^^xsd:string) "imidazole acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.2"^^xsd:string) "acetyl-CoA:imidazole N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.2"^^xsd:string) Annotation( "RHEA:15816"^^xsd:string) "Catalysis of the reaction: 1H-imidazole + acetyl-CoA = N-acetylimidazole + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.2"^^xsd:string) "imidazole acetylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "imidazoleacetate 4-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.5"^^xsd:string) "imidazoleacetate hydroxylase activity"^^xsd:string) AnnotationAssertion( "imidazoleacetic hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.5"^^xsd:string) "4-imidazoleacetate,NADH:oxygen oxidoreductase (5-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.5"^^xsd:string) Annotation( "RHEA:19428"^^xsd:string) "Catalysis of the reaction: H(+) + imidazol-4-ylacetate + NADH + O(2) = 5-hydroxyimidazole-4-acetate + H(2)O + NAD(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.5"^^xsd:string) "imidazoleacetic monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "indanol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.112"^^xsd:string) "indan-1-ol:NAD(P)+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.112"^^xsd:string) Annotation( "MetaCyc:INDANOL-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: indan-1-ol + NAD(P)+ = indanone + NAD(P)H + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "indole 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.17"^^xsd:string) "indole oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.17"^^xsd:string) "indole-oxygen 2,3-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.17"^^xsd:string) "indole:oxygen 2,3-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.17"^^xsd:string) "indole:O2 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.17"^^xsd:string) Annotation( "RHEA:11215"^^xsd:string) "Catalysis of the reaction: indole + O(2) = 2-formamidobenzaldehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.17"^^xsd:string) "IDO"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.99.1.6"^^xsd:string) "3-indoleacetaldoxime hydro-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "indoleacetaldoxime dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.6"^^xsd:string) "indole-3-acetaldehyde-oxime hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.6"^^xsd:string) Annotation( "RHEA:23159"^^xsd:string) "Catalysis of the reaction: (indol-3-yl)acetaldehyde oxime = (indol-3-yl)acetonitrile + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.6"^^xsd:string) "(indol-3-yl)acetaldehyde-oxime hydro-lyase [(indol-3-yl)acetonitrile-forming]"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.6"^^xsd:string) "(indol-3-yl)acetaldehyde-oxime hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.6"^^xsd:string) "indole-3-acetaldoxime hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.6"^^xsd:string) "indoleacetaldoxime hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.20"^^xsd:string) "N-(indole-3-acetyl)-L-lysine synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "indoleacetate-lysine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.20"^^xsd:string) "(indol-3-yl)acetate:L-lysine ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.20"^^xsd:string) Annotation( "RHEA:14860"^^xsd:string) "Catalysis of the reaction: (indol-3-yl)acetate + L-lysine + ATP = N(6)-[(indole-3-yl)acetyl]-L-lysine + ADP + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion( "indoleacetate-lysine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.20"^^xsd:string) "indoleacetate:L-lysine ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.20"^^xsd:string) "IAA-lysine synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.110"^^xsd:string) "indolelactate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.110"^^xsd:string) Annotation( "RHEA:20136"^^xsd:string) "Catalysis of the reaction: 3-(indol-3-yl)lactate + NAD(+) = 3-(indol-3-yl)pyruvate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.110"^^xsd:string) "(indol-3-yl)lactate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion( "indole-3-lactate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "indolelactate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.12"^^xsd:string) "5'-inosinate phosphoribohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inosinate nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.12"^^xsd:string) Annotation( "RHEA:20472"^^xsd:string) "Catalysis of the reaction: H(2)O + IMP = D-ribose 5-phosphate + hypoxanthine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inosine nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.2"^^xsd:string) "inosinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.2"^^xsd:string) Annotation( "MetaCyc:INOSINE-NUCLEOSIDASE-RXN"^^xsd:string) "Catalysis of the reaction: inosine + H2O = D-ribose + hypoxanthine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.2"^^xsd:string) "inosine ribohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.2"^^xsd:string) "inosine-guanosine nucleosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inulosucrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.9"^^xsd:string) "sucrose 1-fructosyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.9"^^xsd:string) "sucrose:2,1-beta-D-fructan 1-beta-D-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.9"^^xsd:string) "sucrose 1-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.9"^^xsd:string) Annotation( "MetaCyc:INULOSUCRASE-RXN"^^xsd:string) "Catalysis of the reaction: sucrose + 2,1-beta-D-fructosyl(n) = glucose + 2,1-beta-D-fructosyl(n+1)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.9.99.1"^^xsd:string) Annotation( "MetaCyc:IRON--CYTOCHROME-C-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: ferrocytochrome c + Fe3+ = ferricytochrome c + Fe2+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.99.1"^^xsd:string) "ferrocytochrome-c:Fe3+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.99.1"^^xsd:string) "iron-cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "iron-cytochrome-c reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.99.13"^^xsd:string) Annotation( "RHEA:13144"^^xsd:string) "Catalysis of the reaction: isobutyryl-CoA = butanoyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "isobutyryl-CoA mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.13"^^xsd:string) "isobutyryl coenzyme A mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.13"^^xsd:string) "2-methylpropanoyl-CoA CoA-carbonylmutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.13"^^xsd:string) "butyryl-CoA:isobutyryl-CoA mutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carnitine 3-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.108"^^xsd:string) Annotation( "RHEA:19268"^^xsd:string) "Catalysis of the reaction: carnitine + NAD(+) = 3-dehydrocarnitine + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.108"^^xsd:string) "carnitine:NAD+ 3-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.42"^^xsd:string) "carnitine carboxy-lyase (2-methylcholine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.42"^^xsd:string) "carnitine carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.42"^^xsd:string) Annotation( "RHEA:21579"^^xsd:string) "Catalysis of the reaction: carnitine + H(+) = 2-methylcholine + CO(2)."^^xsd:string) AnnotationAssertion(rdfs:label "carnitine decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.11"^^xsd:string) "carnosine-homocarnosine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.11"^^xsd:string) "carnosine synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "carnosine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.11"^^xsd:string) "carnosine-anserine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.11"^^xsd:string) "L-histidine:beta-alanine ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.11"^^xsd:string) "homocarnosine-carnosine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.11"^^xsd:string) Annotation( "MetaCyc:CARNOSINE-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + L-histidine + beta-alanine = AMP + diphosphate + carnosine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.14"^^xsd:string) "catechol:oxygen oxidoreductase (dimerizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.14"^^xsd:string) Annotation( "MetaCyc:CATECHOL-OXIDASE-DIMERIZING-RXN"^^xsd:string) "Catalysis of the reaction: 4 catechol + 3 O2 = 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O."^^xsd:string) AnnotationAssertion(rdfs:label "catechol oxidase (dimerizing) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.10"^^xsd:string) "CDP-3,6-dideoxy-D-glucose 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.10"^^xsd:string) "cytidine diphosphoabequose epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.10"^^xsd:string) "cytidine diphosphodideoxyglucose epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.10"^^xsd:string) "CDP-paratose epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.10"^^xsd:string) "CDP-tyvelose 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.10"^^xsd:string) "CDP-D-abequose 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.10"^^xsd:string) "CDP-paratose 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.10"^^xsd:string) Annotation( "RHEA:21659"^^xsd:string) "Catalysis of the reaction: CDP-3,6-dideoxy-D-glucose = CDP-3,6-dideoxy-D-mannose."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.10"^^xsd:string) "cytidine diphosphate paratose-2-epimerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "CDP-abequose epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.10"^^xsd:string) "cytidine diphosphoparatose epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.45"^^xsd:string) "CDPglucose 4,6-dehydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "CDP-glucose 4,6-dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.45"^^xsd:string) "CDP-glucose 4,6-hydro-lyase (CDP-4-dehydro-6-deoxy-D-glucose-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.45"^^xsd:string) "CDPglucose 4,6-hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.45"^^xsd:string) "cytidine diphosphoglucose oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.45"^^xsd:string) Annotation( "RHEA:17156"^^xsd:string) "Catalysis of the reaction: CDP-D-glucose = CDP-4-dehydro-6-deoxy-D-glucose + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.45"^^xsd:string) "CDP-glucose 4,6-hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "CDP-glycerol pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.16"^^xsd:string) "cytidine diphosphoglycerol pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.16"^^xsd:string) "CDPglycerol diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.16"^^xsd:string) "CDPglycerol pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.16"^^xsd:string) "CDP-glycerol phosphoglycerohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.16"^^xsd:string) Annotation( "RHEA:21695"^^xsd:string) "Catalysis of the reaction: CDP-glycerol + H(2)O = sn-glycerol 3-phosphate + CMP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.16"^^xsd:string) "CDPglycerol phosphoglycerohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "CDP-glycerol diphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.18"^^xsd:string) "CDH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.18"^^xsd:string) "cellobiose-quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.18"^^xsd:string) "cellobiose dehydrogenase (quinone) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.18"^^xsd:string) "cellobiose oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.18"^^xsd:string) "CBOR activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.18"^^xsd:string) "cellobiose:(acceptor) 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.18"^^xsd:string) Annotation( "MetaCyc:CELLOBIOSE-DEHYDROGENASE-ACCEPTOR-RXN"^^xsd:string) "Catalysis of the reaction: cellobiose + acceptor = cellobiono-1,5-lactone + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.18"^^xsd:string) "cellobiose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.18"^^xsd:string) "cellobiose oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.18"^^xsd:string) "cellobiose:acceptor 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.18"^^xsd:string) "phanerochaete chrysosporium cellobiose oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.18"^^xsd:string) "cellobiose:oxygen 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cellobiose dehydrogenase (acceptor) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cellobiose epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.11"^^xsd:string) Annotation( "MetaCyc:CELLOBIOSE-EPIMERASE-RXN"^^xsd:string) "Catalysis of the reaction: cellobiose = D-glucosyl-D-mannose."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.11"^^xsd:string) "cellobiose 2-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.20"^^xsd:string) Annotation( "MetaCyc:CELLOBIOSE-PHOSPHORYLASE-RXN"^^xsd:string) "Catalysis of the reaction: cellobiose + phosphate = alpha-D-glucose 1-phosphate + D-glucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.20"^^xsd:string) "cellobiose:phosphate alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cellobiose phosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cephalosporin-C deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.41"^^xsd:string) "cephalosporin C acetylesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.41"^^xsd:string) "cephalosporin C acetyl-hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.41"^^xsd:string) "cephalosporin C acetyl-esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.41"^^xsd:string) "cephalosporin-C acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.41"^^xsd:string) Annotation( "RHEA:22599"^^xsd:string) "Catalysis of the reaction: cephalosporin C + H(2)O = acetate + deacetylcephalosporin C + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.41"^^xsd:string) "cephalosporin C deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.41"^^xsd:string) "cephalosporin C acetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.41"^^xsd:string) "cephalosporin acetylesterase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.74"^^xsd:string) "L-alanine:cephalosporin-C aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.74"^^xsd:string) "cephalosporin C aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.74"^^xsd:string) Annotation( "RHEA:14556"^^xsd:string) "Catalysis of the reaction: (7R)-7-(5-carboxylato-5-oxopentanamido)deacetylcephalosporanate + D-glutamate = 2-oxoglutarate + cephalosporin C."^^xsd:string) AnnotationAssertion(rdfs:label "cephalosporin-C transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.74"^^xsd:string) "cephalosporin-C:2-oxoglutarate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cetraxate benzylesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.70"^^xsd:string) "cetraxate-benzyl-ester benzylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.70"^^xsd:string) Annotation( "RHEA:23463"^^xsd:string) "Catalysis of the reaction: benzyl cetraxate + H(2)O = benzyl alcohol + cetraxate + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.74"^^xsd:string) Annotation( "MetaCyc:CHENODEOXYCHOLOYLTAURINE-HYDROLASE-RXN"^^xsd:string) "Catalysis of the reaction: chenodeoxycholoyltaurine + H2O = chenodeoxycholate + taurine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.74"^^xsd:string) "chenodeoxycholoyltaurine amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "chenodeoxycholoyltaurine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.225"^^xsd:string) Annotation( "RHEA:14404"^^xsd:string) "Catalysis of the reaction: chlordecone alcohol + NADP(+) = chlordecone + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.225"^^xsd:string) "CDR activity"^^xsd:string) AnnotationAssertion(rdfs:label "chlordecone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.225"^^xsd:string) "chlordecone-alcohol:NADP+ 2-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chloridazon-catechol dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.36"^^xsd:string) "5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone 1,2-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.36"^^xsd:string) Annotation( "RHEA:20452"^^xsd:string) "Catalysis of the reaction: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O(2) = 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.42"^^xsd:string) "chlorogenic acid esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.42"^^xsd:string) "chlorogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.42"^^xsd:string) Annotation( "RHEA:20692"^^xsd:string) "Catalysis of the reaction: chlorogenate + H(2)O = (-)-quinate + cis-caffeate + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "chlorogenate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.14"^^xsd:string) Annotation( "MetaCyc:CHLOROPHYLLASE-RXN"^^xsd:string) "Catalysis of the reaction: chlorophyll + H2O = phytol + chlorophyllide."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.14"^^xsd:string) "chlorophyll chlorophyllidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "chlorophyllase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "choloyl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "cholic thiokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.7"^^xsd:string) Annotation( "MetaCyc:CHOLATE--COA-LIGASE-RXN"^^xsd:string) "Catalysis of the reactions: (1) ATP + cholate + CoA = AMP + diphosphate + choloyl-CoA and (2) ATP + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA = AMP + diphosphate + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate:CoA ligase (AMP-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "cholate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "choloyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate--CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "THCA-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "cholate thiokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "cholate:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "cholic acid:CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "trihydroxycoprostanoyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion( "3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "BAL activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "bile acid CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "cholyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "bile acid coenzyme A ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.29"^^xsd:string) "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate-CoA ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.161"^^xsd:string) "5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol:NAD+ 26-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.161"^^xsd:string) "cholestanetetrol 26-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.161"^^xsd:string) "5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.161"^^xsd:string) "TEHC-NAD oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.161"^^xsd:string) Annotation( "MetaCyc:CHOLESTANETETRAOL-26-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NAD+ = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "cholestanetetraol 26-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.15"^^xsd:string) "cytochrome P450 27A1' activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.15"^^xsd:string) "CYP27A1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.15"^^xsd:string) Annotation( "MetaCyc:CHOLESTANETRIOL-26-MONOOXYGENASE-RXN"^^xsd:string) "Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol + NADPH + O2 = 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NADP+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.15"^^xsd:string) "5beta-cholestane-3alpha,7alpha,12alpha-triol hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cholestanetriol 26-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.15"^^xsd:string) "sterol 26-hydroxylase activity"^^xsd:string) AnnotationAssertion( "cholestanetriol 26-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.15"^^xsd:string) "5beta-cholestane-3alpha,7alpha,12alpha-triol,NADPH:oxygen oxidoreductase (26-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.15"^^xsd:string) "5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.15"^^xsd:string) "5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.15"^^xsd:string) "5beta-cholestane-3alpha,7alpha,12alpha-triol 26-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.15"^^xsd:string) "CYP27A"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.15"^^xsd:string) "cholesterol 27-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.15"^^xsd:string) "sterol 27-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cholestenol delta-isomerase activity"^^xsd:string) AnnotationAssertion( "cholestenol D-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.5"^^xsd:string) "delta7-cholestenol delta7-delta8-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.5"^^xsd:string) Annotation( "MetaCyc:CHOLESTENOL-DELTA-ISOMERASE-RXN"^^xsd:string) "Catalysis of the reaction: 5-alpha-cholest-7-en-3-beta-ol = 5-alpha-cholest-8-en-3-beta-ol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.22"^^xsd:string) "3-oxosteroid delta4-dehydrogenase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.22"^^xsd:string) "delta4-3-ketosteroid 5alpha-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.22"^^xsd:string) "3-oxosteroid 5alpha-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.22"^^xsd:string) "cholestenone 5alpha-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.22"^^xsd:string) "4-ene-3-oxosteroid 5alpha-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.22"^^xsd:string) "5alpha-reductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.22"^^xsd:string) "testosterone delta4-hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.22"^^xsd:string) "3-oxo-5alpha-steroid:NADP+ delta4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.22"^^xsd:string) "cholest-4-en-3-one 5alpha-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.22"^^xsd:string) "testosterone delta4-5alpha-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.22"^^xsd:string) "reduced nicotinamide adenine dinucleotide phosphate:Delta4-3-ketosteroid 5alpha-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.22"^^xsd:string) Annotation( "RHEA:24555"^^xsd:string) "Catalysis of the reaction: 5alpha-cholestan-3-one + NADP(+) = cholest-4-en-3-one + H(+) + NADPH."^^xsd:string) AnnotationAssertion( "cholestenone 5a-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.22"^^xsd:string) "steroid 5alpha-hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.22"^^xsd:string) "4-ene-5alpha-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.22"^^xsd:string) "steroid 5alpha-reductase"^^xsd:string) AnnotationAssertion(rdfs:label "cholestenone 5-alpha-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.22"^^xsd:string) "testosterone 5alpha-reductase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "choline-sulphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.6"^^xsd:string) Annotation( "RHEA:20823"^^xsd:string) "Catalysis of the reaction: choline sulfate + H(2)O = choline + H(+) + sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.6"^^xsd:string) "choline-sulfate sulfohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "choline-sulfatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.6"^^xsd:string) "3'-phosphoadenylyl-sulfate:choline sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.6"^^xsd:string) Annotation( "RHEA:21987"^^xsd:string) "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + choline = adenosine 3',5'-diphosphate + choline sulfate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.6"^^xsd:string) "choline sulphokinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "choline sulfotransferase activity"^^xsd:string) AnnotationAssertion( "choline sulphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.2.6"^^xsd:string) "(1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate 1-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.2.6"^^xsd:string) Annotation( "RHEA:10823"^^xsd:string) "Catalysis of the reaction: D-threo-isocitrate = D-erythro-isocitrate."^^xsd:string) AnnotationAssertion(rdfs:label "isocitrate epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.5"^^xsd:string) "3'-phosphoadenylyl-sulfate:chondroitin 4'-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.5"^^xsd:string) Annotation( "MetaCyc:CHONDROITIN-4-SULFOTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate."^^xsd:string) AnnotationAssertion( "chondroitin 4-sulphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "chondroitin 4-sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.19"^^xsd:string) "dermatan-sulfate 5-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.19"^^xsd:string) "urunosyl C-5 epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.19"^^xsd:string) "polyglucuronate 5-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.19"^^xsd:string) "chondroitin-D-glucuronate 5-epimerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "chondroitin-glucuronate 5-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.19"^^xsd:string) Annotation( "MetaCyc:CHONDROITIN-GLUCURONATE-5-EPIMERASE-RXN"^^xsd:string) "Catalysis of the reaction: chondroitin D-glucuronate = dermatan L-iduronate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.19"^^xsd:string) "chondroitin D-glucuronosyl 5-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.2.14"^^xsd:string) "isobutyrate kinase activity"^^xsd:string) AnnotationAssertion( "ATP:2-methylpropanoate 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.14"^^xsd:string) "branched-chain fatty acid kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.14"^^xsd:string) Annotation( "RHEA:24159"^^xsd:string) "Catalysis of the reaction: 2-methylpropanoate + ATP = 2-methylpropanoyl phosphate + ADP + H(+)."^^xsd:string) AnnotationAssertion( "ATP:2-methylpropanoate kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ATP:2-methylpropanoate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.14"^^xsd:string) Annotation( "KEGG:R04002"^^xsd:string) "ATP:branched-chain-fatty-acid 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion( "ATP:isobutyrate 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.14"^^xsd:string) "branched-chain-fatty-acid kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "butanal dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.57"^^xsd:string) "butanal:NAD(P)+ oxidoreductase (CoA-acylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.57"^^xsd:string) Annotation( "MetaCyc:BUTANAL-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: butanal + CoA + NAD(P)+ = butanoyl-CoA + NAD(P)H + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.2"^^xsd:string) Annotation( "MetaCyc:BUTYRATE--COA-LIGASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.2"^^xsd:string) "acyl-activating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.2"^^xsd:string) "butanoate:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.2"^^xsd:string) "medium chain acyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.2"^^xsd:string) "short-chain acyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.2"^^xsd:string) "L-(+)-3-hydroxybutyryl CoA ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "butyrate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.2"^^xsd:string) "butyryl-coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.2"^^xsd:string) "fatty acid thiokinase (medium chain) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.2"^^xsd:string) "butyryl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.2"^^xsd:string) "fatty acyl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.2"^^xsd:string) "fatty acid activating enzyme"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.2.7"^^xsd:string) Annotation( "RHEA:13588"^^xsd:string) "Catalysis of the reaction: ATP + butanoate = ADP + butanoyl phosphate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.7"^^xsd:string) "ATP:butanoate 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "butyrate kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.22"^^xsd:string) "3,4-dihydroxy-trans-cinnamate:oxygen 3,4-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.22"^^xsd:string) Annotation( "RHEA:22219"^^xsd:string) "Catalysis of the reaction: trans-caffeate + O(2) = 3-(2-carboxyethenyl)-cis,cis-muconate + 2 H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "caffeate 3,4-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.68"^^xsd:string) Annotation( "MetaCyc:CAFFEATE-O-METHYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.68"^^xsd:string) "caffeate 3-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.68"^^xsd:string) "S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.68"^^xsd:string) "caffeate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.68"^^xsd:string) "S-adenosyl-L-methionine:caffeic acid-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "caffeate O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "Catalysis of the reaction: ATP + caldesmon = ADP + caldesmon phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "caldesmon kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.55"^^xsd:string) "smooth muscle caldesmon phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.55"^^xsd:string) Annotation( "MetaCyc:CALDESMON-PHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: caldesmon phosphate + H2O = caldesmon + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "caldesmon-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.55"^^xsd:string) "caldesmon-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.55"^^xsd:string) "SMP-I"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.1.13"^^xsd:string) Annotation( "RHEA:15448"^^xsd:string) "Catalysis of the reaction: O-carbamoyl-L-serine + H(2)O + H(+) = CO(2) + 2 NH(4)(+) + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.13"^^xsd:string) "O-carbamoyl-L-serine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.13"^^xsd:string) "O-carbamoyl-L-serine ammonia-lyase (pyruvate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "carbamoyl-serine ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.13"^^xsd:string) "carbamoylserine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.13"^^xsd:string) "O-carbamoyl-L-serine ammonia-lyase (decarboxylating; pyruvate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.5.1.5"^^xsd:string) "3-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.5"^^xsd:string) "3-carboxy-cis,cis-muconate lactonizing enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "carboxy-cis,cis-muconate cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.5"^^xsd:string) Annotation( "RHEA:14980"^^xsd:string) "Catalysis of the reaction: 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.5"^^xsd:string) "3-carboxymuconate cyclase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.91"^^xsd:string) Annotation( "MetaCyc:CARBOXYCYCLOHEXADIENYL-DEHYDRATASE-RXN"^^xsd:string) "Catalysis of the reaction: L-arogenate = L-phenylalanine + H2O + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.91"^^xsd:string) "L-arogenate hydro-lyase (decarboxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "arogenate dehydratase activity"^^xsd:string) AnnotationAssertion( "carboxycyclohexadienyl dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.91"^^xsd:string) "L-arogenate hydro-lyase (decarboxylating; L-phenylalanine-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.99.6"^^xsd:string) Annotation( "MetaCyc:CARBOXYLATE-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: an aldehyde + acceptor + H2O = a carboxylate + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.99.6"^^xsd:string) "aldehyde:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.99.6"^^xsd:string) "aldehyde:(acceptor) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.99.6"^^xsd:string) "carboxylic acid reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "carboxylate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.2.4"^^xsd:string) Annotation( "RHEA:12031"^^xsd:string) "Catalysis of the reaction: L-5-carboxymethylhydantoin + H(2)O = N-carbamoyl-L-aspartate + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "carboxymethylhydantoinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.4"^^xsd:string) "L-5-carboxymethylhydantoin amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.4"^^xsd:string) "hydantoin hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.99.12"^^xsd:string) Annotation( "RHEA:12339"^^xsd:string) "Catalysis of the reaction: carboxymethoxysuccinate = fumarate + glycolate."^^xsd:string) AnnotationAssertion(rdfs:label "carboxymethyloxysuccinate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.12"^^xsd:string) "carboxymethyloxysuccinate glycolate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.12"^^xsd:string) "carboxymethyloxysuccinate glycolate-lyase (fumarate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carnitinamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.73"^^xsd:string) "L-carnitinamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.73"^^xsd:string) "L-carnitinamide amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.73"^^xsd:string) "carnitine amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.73"^^xsd:string) Annotation( "RHEA:17540"^^xsd:string) "Catalysis of the reaction: (R)-carnitinamide + H(2)O = (R)-carnitine + NH(4)(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.73"^^xsd:string) "L-carnitine amidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.37"^^xsd:string) "reductase, cis-2-enoyl coenzyme A"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.37"^^xsd:string) "cis-2-enoyl-coenzyme A reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.37"^^xsd:string) "NADPH-dependent cis-enoyl-CoA reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cis-2-enoyl-CoA reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.37"^^xsd:string) "acyl-CoA:NADP+ cis-2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.37"^^xsd:string) Annotation( "MetaCyc:CIS-2-ENOYL-COA-REDUCTASE-NADPH-RXN"^^xsd:string) "Catalysis of the reaction: acyl-CoA + NADP+ = cis-2,3-dehydroacyl-CoA + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.3.11"^^xsd:string) Annotation( "MetaCyc:CITRAMALATE-COA-TRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + citramalate = acetate + (3S)-citramalyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.11"^^xsd:string) "acetyl-CoA:citramalate CoA-transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "citramalate CoA-transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3.22"^^xsd:string) Annotation( "RHEA:15548"^^xsd:string) "Catalysis of the reaction: S-citramalate = acetate + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.22"^^xsd:string) "citramalic-condensing enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.22"^^xsd:string) "citramalate pyruvate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.22"^^xsd:string) "(3S)-citramalate pyruvate-lyase (acetate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.22"^^xsd:string) "citramalate pyruvate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.22"^^xsd:string) "citramalate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.22"^^xsd:string) "(+)-citramalate pyruvate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.22"^^xsd:string) "citramalic synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.22"^^xsd:string) "(S)-citramalate lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "citramalate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.22"^^xsd:string) "(3S)-citramalate pyruvate-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3.25"^^xsd:string) "(+)-CMA-CoA lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.25"^^xsd:string) "(3S)-citramalyl-CoA pyruvate-lyase (acetyl-CoA-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.25"^^xsd:string) "citramalyl coenzyme A lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.25"^^xsd:string) Annotation( "RHEA:22615"^^xsd:string) "Catalysis of the reaction: (3S)-citramalyl-CoA = acetyl-CoA + pyruvate."^^xsd:string) AnnotationAssertion(rdfs:label "(3S)-citramalyl-CoA lyase activity"^^xsd:string) AnnotationAssertion( "citramalyl-CoA lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.25"^^xsd:string) "(3S)-citramalyl-CoA pyruvate-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.2.16"^^xsd:string) "citrate-(pro-3S)-lyase thioesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.16"^^xsd:string) "citrate lyase deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.16"^^xsd:string) Annotation( "MetaCyc:CITRATE-PRO-3S-LYASE-THIOLESTERASE-RXN"^^xsd:string) "Catalysis of the reaction: [citrate (pro-3S)-lyase](acetyl form) + H2O = [citrate (pro-3S)-lyase](thiol form) + acetate."^^xsd:string) AnnotationAssertion(rdfs:label "[citrate-(pro-3S)-lyase] thiolesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.16"^^xsd:string) "[citrate-(pro-3S)-lyase] thioesterase activity"^^xsd:string) AnnotationAssertion( "citrate (pro-3S)-lyase thiolesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.16"^^xsd:string) "citrate-(pro-3S)-lyase(acetyl-form) hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.16"^^xsd:string) "citrate-(pro-3S)-lyase thiolesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.18"^^xsd:string) Annotation( "RHEA:21475"^^xsd:string) "Catalysis of the reaction: ATP + citrate + CoA = (3S)-citryl-CoA + ADP + H(+) + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "citrate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.18"^^xsd:string) "citryl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.18"^^xsd:string) "citrate:CoA ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.18"^^xsd:string) "citrate thiokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.18"^^xsd:string) "citrate:CoA ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.3"^^xsd:string) Annotation( "EC:4.2.1.4"^^xsd:string) "citrate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.3"^^xsd:string) "aconitate hydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "citrate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.4"^^xsd:string) "citrate hydro-lyase (cis-aconitate-forming)"^^xsd:string) AnnotationAssertion( "citrate hydro-lyase (cis-aconitate-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.4"^^xsd:string) "Catalysis of the reaction: citrate = cis-aconitate + H2O."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "citrullinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.20"^^xsd:string) "L-citrulline 5-N-carbamoyldihydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.20"^^xsd:string) "citrulline hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.20"^^xsd:string) "L-citrulline N5-carbamoyldihydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.20"^^xsd:string) Annotation( "MetaCyc:CITRULLINASE-RXN"^^xsd:string) "Catalysis of the reaction: H2O + citrulline = NH3 + CO2 + L-ornithine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.20"^^xsd:string) "citrulline ureidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "coniferin beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.126"^^xsd:string) Annotation( "MetaCyc:CONIFERIN-BETA-GLUCOSIDASE-RXN"^^xsd:string) "Catalysis of the reaction: H2O + coniferin = D-glucose + coniferol."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.126"^^xsd:string) "coniferin beta-D-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.126"^^xsd:string) "coniferin-hydrolyzing beta-glucosidase activity"^^xsd:string) AnnotationAssertion( "coniferin b-glucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "corticosterone 18-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.5"^^xsd:string) "corticosterone methyl oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.5"^^xsd:string) "corticosterone,reduced-adrenal-ferredoxin:oxygen oxidoreductase (18-hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "corticosterone 18-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.15.5"^^xsd:string) Annotation( "MetaCyc:CORTICOSTERONE-18-MONOOXYGENASE-RXN"^^xsd:string) "Catalysis of the reaction: corticosterone + reduced adrenal ferredoxin + O2 = 18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cortisol O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.27"^^xsd:string) "corticosteroid-21-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.27"^^xsd:string) "acetyl-CoA:cortisol O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.27"^^xsd:string) Annotation( "RHEA:17076"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + cortisol = CoA + cortisol 21-acetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.27"^^xsd:string) "cortisol acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.27"^^xsd:string) "corticosteroid acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.18"^^xsd:string) "3'-phosphoadenylyl-sulfate:cortisol 21-sulfotransferase activity"^^xsd:string) AnnotationAssertion( "cortisol sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.18"^^xsd:string) "glucocorticosteroid sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.18"^^xsd:string) Annotation( "RHEA:11887"^^xsd:string) "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + cortisol = adenosine 3',5'-diphosphate + cortisol 21-sulfate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.18"^^xsd:string) "glucocorticoid sulfotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cortisol sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.4"^^xsd:string) "microsomal steroid reductase (5alpha)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.4"^^xsd:string) "cortisone delta4-5alpha-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.4"^^xsd:string) "4,5alpha-dihydrocortisone:NADP+ delta4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.4"^^xsd:string) "NADPH:Delta4-3-oxosteroid-5alpha-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.4"^^xsd:string) "delta4-3-ketosteroid reductase (5alpha)"^^xsd:string) AnnotationAssertion(rdfs:label "cortisone alpha-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.4"^^xsd:string) Annotation( "RHEA:17984"^^xsd:string) "Catalysis of the reaction: 4,5alpha-dihydrocortisone + NADP(+) = cortisone + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.4"^^xsd:string) "delta4-5alpha-reductase activity"^^xsd:string) AnnotationAssertion( "cortisone a-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.4"^^xsd:string) "delta4-3-oxosteroid-5alpha-reductase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "5beta-cholestan-3-one:NADP+ 4,5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "steroid 5beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "delta(4)-3-ketosteroid 5-beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "4,5beta-dihydrocortisone:NADP+ delta4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "testosterone 5-beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "5beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "cholestenone 5beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "delta(4)-5-beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "androstenedione 5-beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "cortisone delta(4)-5-beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "steroid 5-beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "3-oxo-5beta-steroid:NADP+ delta4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "5-beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.3"^^xsd:string) Annotation( "MetaCyc:CORTISONE-BETA-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reactions: (1) 5beta-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ and (2) 17,21-dihydroxy-5beta-pregnane-3,11,20-trione + NADP+ = cortisone + NADPH + H+."^^xsd:string) AnnotationAssertion( "cortisone beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "androstenedione 5beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "testosterone 5beta-reductase activity"^^xsd:string) AnnotationAssertion( "cholestenone 5-beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "delta4-hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "3-oxo-Delta(4)-steroid 5-beta-reductase activity"^^xsd:string) AnnotationAssertion( "cholestenone 5b-reductase activity"^^xsd:string) AnnotationAssertion( "delta4-3-oxosteroid 5-beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "delta(4)-hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "delta4-3-ketosteroid 5beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "delta4-5beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "cortisone delta4-5beta-reductase activity"^^xsd:string) AnnotationAssertion( "cortisone b-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "cortisone 5-beta-reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "delta4-3-oxosteroid 5beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "3-oxo-delta4-steroid 5beta-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.23"^^xsd:string) "cortisone 5beta-reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.11"^^xsd:string) Annotation( "RHEA:21447"^^xsd:string) "Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + NAD(+) = trans-2-coumarate + H(+) + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "2-coumarate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.11"^^xsd:string) "3-(2-hydroxyphenyl)propanoate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.11"^^xsd:string) "melilotate dehydrogenase activity"^^xsd:string) AnnotationAssertion( "coumarate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.2.10"^^xsd:string) Annotation( "RHEA:14536"^^xsd:string) "Catalysis of the reaction: creatinine + H(2)O = creatine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.10"^^xsd:string) "creatinine amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "creatininase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.10"^^xsd:string) "creatinine hydrolase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.21"^^xsd:string) "creatinine hydrolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.21"^^xsd:string) "creatinine iminohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "creatinine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.21"^^xsd:string) "creatinine desiminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.21"^^xsd:string) Annotation( "MetaCyc:CREATININE-DEAMINASE-RXN"^^xsd:string) "Catalysis of the reaction: creatinine + H2O = N-methylhydantoin + NH3."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.5"^^xsd:string) Annotation( "MetaCyc:CUCURBITACIN-DELTA-23-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: 23,24-dihydrocucurbitacin + NAD(P)+ = cucurbitacin + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.5"^^xsd:string) "23,24-dihydrocucurbitacin:NAD(P)+ delta23-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.5"^^xsd:string) "NAD(P)H: cucurbitacin B delta23-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cucurbitacin delta23-reductase activity"^^xsd:string) AnnotationAssertion( "cucurbitacin D23-reductase activity"^^xsd:string) AnnotationAssertion( "cucurbitacin delta(23) reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.85"^^xsd:string) Annotation( "MetaCyc:CYANOHYDRIN-BETA-GLUCOSYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: UDP-glucose + (S)-4-hydroxymandelonitrile = UDP + (S)-4-hydroxy-mandelonitrile beta-D-glucoside."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.85"^^xsd:string) "UDP-glucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.85"^^xsd:string) "UDP-glucose:p-hydroxymandelonitrile-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.85"^^xsd:string) "UDP-D-glucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "cyanohydrin b-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.85"^^xsd:string) "uridine diphosphoglucose-p-hydroxymandelonitrile glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.85"^^xsd:string) "UGT85B1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.85"^^xsd:string) "uridine diphosphoglucose-cyanohydrin glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.85"^^xsd:string) "uridine diphosphoglucose:aldehyde cyanohydrin beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.85"^^xsd:string) "UDP-glucose-p-hydroxymandelonitrile glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyanohydrin beta-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cycloeucalenol cycloisomerase activity"^^xsd:string) AnnotationAssertion( "cycloeucalenol-obtusifoliol isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.9"^^xsd:string) "cycloeucalenol--obtusifoliol isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.9"^^xsd:string) "cycloeucalenol lyase (cyclopropane-decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.9"^^xsd:string) Annotation( "RHEA:22803"^^xsd:string) "Catalysis of the reaction: cycloeucalenol = obtusifoliol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.43"^^xsd:string) "arogenic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.43"^^xsd:string) "L-arogenate:NAD+ oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.43"^^xsd:string) "L-arogenate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyclohexadienyl dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.43"^^xsd:string) Annotation( "MetaCyc:CYCLOHEXADIENYL-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: L-arogenate + NAD+ = L-tyrosine + NADH + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.43"^^xsd:string) "pretyrosine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.43"^^xsd:string) "arogenate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.43"^^xsd:string) "L-arogenate:NAD(+) oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclohexane-1,2-diol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.174"^^xsd:string) Annotation( "MetaCyc:CYCLOHEXANE-12-DIOL-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: trans-cyclohexane-1,2-diol + NAD+ = 2-hydroxycyclohexan-1-one + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.174"^^xsd:string) "trans-cyclohexane-1,2-diol:NAD+ 1-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclohexane-1,3-dione hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.10"^^xsd:string) "1,3-cyclohexanedione hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.10"^^xsd:string) Annotation( "RHEA:16476"^^xsd:string) "Catalysis of the reaction: cyclohexane-1,3-dione + H(2)O = 5-oxohexanoate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.10"^^xsd:string) "cyclohexane-1,3-dione acylhydrolase (decyclizing)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.99.14"^^xsd:string) Annotation( "RHEA:21783"^^xsd:string) "Catalysis of the reaction: A + cyclohexanone = AH(2) + cyclohex-2-enone."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.14"^^xsd:string) "cyclohexanone:acceptor 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyclohexanone dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.14"^^xsd:string) "cyclohexanone:(acceptor) 2-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.54"^^xsd:string) "cycloheptaglucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.54"^^xsd:string) Annotation( "MetaCyc:CYCLOMALTODEXTRINASE-RXN"^^xsd:string) "Catalysis of the reaction: H2O + cyclomaltodextrin = linear maltodextrin."^^xsd:string) AnnotationAssertion(rdfs:label "cyclomaltodextrinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.54"^^xsd:string) "cyclohexaglucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.54"^^xsd:string) "cyclomaltodextrin dextrin-hydrolase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.54"^^xsd:string) "cyclodextrinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.16"^^xsd:string) "cyclopentanone,NADPH:oxygen oxidoreductase (5-hydroxylating, lactonizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.16"^^xsd:string) Annotation( "RHEA:15740"^^xsd:string) "Catalysis of the reaction: cyclopentanone + H(+) + NADPH + O(2) = 5-valerolactone + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.16"^^xsd:string) "cyclopentanone oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.16"^^xsd:string) "cyclopentanone 1,2-monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyclopentanone monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.19"^^xsd:string) Annotation( "RHEA:14412"^^xsd:string) "Catalysis of the reaction: cysteamine + O(2) = H(+) + hypotaurine."^^xsd:string) AnnotationAssertion(rdfs:label "cysteamine dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.19"^^xsd:string) "2-aminoethanethiol:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.19"^^xsd:string) "persulfurase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.19"^^xsd:string) "cysteamine oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.19"^^xsd:string) "cysteamine:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cysteine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.3"^^xsd:string) "L-cysteine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.3"^^xsd:string) "cysteine transaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-cysteine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.3"^^xsd:string) "CGT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.3"^^xsd:string) Annotation( "MetaCyc:CYSTEINE-AMINOTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: L-cysteine + 2-oxoglutarate = mercaptopyruvate + L-glutamate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.75"^^xsd:string) "cysteine-conjugate alpha-ketoglutarate transaminase (CAT-1)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.75"^^xsd:string) "cysteine conjugate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cysteine-conjugate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.75"^^xsd:string) Annotation( "RHEA:13488"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + S-(4-bromophenyl)-L-cysteine = (4-bromophenylsulfanyl)pyruvate + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.75"^^xsd:string) "S-(4-bromophenyl)-L-cysteine:2-oxoglutarate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.10"^^xsd:string) Annotation( "MetaCyc:CYSTEINE-LYASE-RXN"^^xsd:string) "Catalysis of the reaction: L-cysteine + sulfite = L-cysteate + sulfide."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.10"^^xsd:string) "cysteine (sulfite) lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.10"^^xsd:string) "L-cysteine hydrogen-sulfide-lyase (adding sulfite)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.10"^^xsd:string) "L-cysteine hydrogen-sulfide-lyase (adding sulfite; L-cysteate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "cysteine lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cysteine-S-conjugate beta-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.13"^^xsd:string) "L-cysteine-S-conjugate thiol-lyase (deaminating; pyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.13"^^xsd:string) "L-cysteine-S-conjugate thiol-lyase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.13"^^xsd:string) "glutamine transaminase K/cysteine conjugate beta-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.13"^^xsd:string) "cysteine conjugate beta-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.13"^^xsd:string) Annotation( "MetaCyc:CYSTEINE-S-CONJUGATE-BETA-LYASE-RXN"^^xsd:string) "Catalysis of the reaction: RS-CH2-CH(NH3+)COO- = RSH + NH3 + pyruvate."^^xsd:string) AnnotationAssertion( "cysteine-S-conjugate b-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.6.1.6"^^xsd:string) "3',5'-cyclic-CMP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.6"^^xsd:string) "CTP diphosphate-lyase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.6"^^xsd:string) "cytidyl cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.6"^^xsd:string) "CTP diphosphate-lyase (cyclizing; 3',5'-cyclic-CMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.6"^^xsd:string) "3'5'-cyclic-CMP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.6"^^xsd:string) "cytidylyl cyclase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cytidylate cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.6.1.6"^^xsd:string) Annotation( "RHEA:14740"^^xsd:string) "Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.12.2.1"^^xsd:string) "hydrogen:ferricytochrome-c3 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.2.1"^^xsd:string) "H(2):ferricytochrome c3 oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cytochrome-c3 hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.2.1"^^xsd:string) "cytochrome hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.2.1"^^xsd:string) "H2:ferricytochrome c3 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.2.1"^^xsd:string) "cytochrome c3 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.2.1"^^xsd:string) Annotation( "MetaCyc:CYTOCHROME-C3-HYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: 2 H2 + ferricytochrome c3 = 4 H+ + ferrocytochrome c3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.118"^^xsd:string) "UDP-glucose:zeatin 7-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.118"^^xsd:string) "UDPglucose:zeatin 7-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cytokinin 7-beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.118"^^xsd:string) Annotation( "MetaCyc:CYTOKININ-7-BETA-GLUCOSYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-7-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.118"^^xsd:string) "UDP-glucose-zeatin 7-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.118"^^xsd:string) "uridine diphosphoglucose-zeatin 7-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.118"^^xsd:string) "cytokinin 7-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "cytokinin 7-b-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D(-)-tartrate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.81"^^xsd:string) Annotation( "RHEA:18292"^^xsd:string) "Catalysis of the reaction: D-tartrate = H(2)O + oxaloacetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.81"^^xsd:string) "(S,S)-tartrate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.81"^^xsd:string) "(S,S)-tartrate hydro-lyase (oxaloacetate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.81"^^xsd:string) "D-tartrate dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.6"^^xsd:string) Annotation( "RHEA:15092"^^xsd:string) "Catalysis of the reaction: (R)-lactate + A = AH(2) + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.6"^^xsd:string) "2-hydroxy acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.6"^^xsd:string) "(R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-2-hydroxy-acid dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.21"^^xsd:string) Annotation( "MetaCyc:D-ALANINE-AMINOTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: D-alanine + 2-oxoglutarate = pyruvate + D-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.21"^^xsd:string) "D-aspartate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.21"^^xsd:string) "D-alanine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.21"^^xsd:string) "D-aspartic aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.21"^^xsd:string) "D-amino acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.21"^^xsd:string) "D-amino acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.21"^^xsd:string) "D-amino-acid transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.21"^^xsd:string) "D-aspartate transaminase activity"^^xsd:string) AnnotationAssertion( "D-alanine aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-alanine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.21"^^xsd:string) "D-alanine-D-glutamate transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "D-alanine g-glutamyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-alanine gamma-glutamyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.14"^^xsd:string) Annotation( "RHEA:23559"^^xsd:string) "Catalysis of the reaction: D-alanine + L-glutamine = gamma-L-glutamyl-D-alanine + NH(4)(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.14"^^xsd:string) "L-glutamine:D-alanine gamma-glutamyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.36"^^xsd:string) "D-amino acid acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-amino-acid N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.36"^^xsd:string) Annotation( "MetaCyc:D-AMINO-ACID-N-ACETYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + a D-amino acid = CoA + an N-acetyl-D-amino-acid."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.36"^^xsd:string) "D-amino acid-alpha-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.36"^^xsd:string) "acetyl-CoA:D-amino-acid N-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.11"^^xsd:string) Annotation( "MetaCyc:D-ARABINITOL-4-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: D-arabinitol + NAD+ = D-xylulose + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "D-arabinitol 4-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.54"^^xsd:string) "ATP:D-arabinose 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.54"^^xsd:string) Annotation( "RHEA:24591"^^xsd:string) "Catalysis of the reaction: D-arabinose + ATP = D-arabinose 5-phosphate + ADP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.54"^^xsd:string) "D-arabinokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "D-arabinokinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.30"^^xsd:string) Annotation( "RHEA:23111"^^xsd:string) "Catalysis of the reaction: D-arabinono-1,4-lactone + H(2)O = D-arabinonate + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "D-arabinonolactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.30"^^xsd:string) "D-arabinono-1,4-lactone lactonohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.116"^^xsd:string) "D-arabinose:NAD+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-arabinose 1-dehydrogenase (NAD) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.116"^^xsd:string) "arabinose(fucose)dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.116"^^xsd:string) Annotation( "MetaCyc:D-ARABINOSE-1-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: D-arabinose + NAD+ = D-arabinono-1,4-lactone + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.116"^^xsd:string) "NAD-pentose-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.10"^^xsd:string) Annotation( "RHEA:12904"^^xsd:string) "Catalysis of the reaction: D-arginine + H(2)O = D-ornithine + urea."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.10"^^xsd:string) "D-arginine amidinohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-arginase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.67"^^xsd:string) "D-fuconate hydro-lyase (2-dehydro-3-deoxy-D-fuconate-forming)"^^xsd:string) AnnotationAssertion( "D-fuconate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.67"^^xsd:string) Annotation( "RHEA:12952"^^xsd:string) "Catalysis of the reaction: D-fuconate = 2-dehydro-3-deoxy-D-fuconate + H(2)O."^^xsd:string) AnnotationAssertion(rdfs:label "D-fuconate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.67"^^xsd:string) "D-fuconate hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-glutamate(D-aspartate) oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.15"^^xsd:string) Annotation( "MetaCyc:D-GLUTAMATED-ASPARTATE-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2, and D-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.15"^^xsd:string) "D-glutamate(D-aspartate):oxygen oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.15"^^xsd:string) "D-monoaminodicarboxylic acid oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.15"^^xsd:string) "D-glutamic-aspartic oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-glutamate cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.48"^^xsd:string) Annotation( "RHEA:22363"^^xsd:string) "Catalysis of the reaction: D-glutamate = 5-oxo-D-proline + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.48"^^xsd:string) "D-glutamate hydro-lyase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.48"^^xsd:string) "D-glutamate hydro-lyase (cyclizing; 5-oxo-D-proline-forming)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.3.7"^^xsd:string) "D-glutamic acid oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.7"^^xsd:string) "D-glutamic oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.7"^^xsd:string) Annotation( "MetaCyc:D-GLUTAMATE-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.7"^^xsd:string) "D-glutamate:oxygen oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(rdfs:label "D-glutamate oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.1.3"^^xsd:string) "hypotaurine:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.3"^^xsd:string) Annotation( "RHEA:17388"^^xsd:string) "Catalysis of the reaction: H(2)O + hypotaurine + NAD(+) = H(+) + NADH + taurine."^^xsd:string) AnnotationAssertion(rdfs:label "hypotaurine dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-glutamyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.1"^^xsd:string) "D-gamma-glutamyl transpeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.1"^^xsd:string) Annotation( "MetaCyc:D-GLUTAMYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: L(or D)-glutamine + D-glutamyl-peptide = NH3 + 5-glutamyl-D-glutamyl-peptide."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.1"^^xsd:string) "glutamine:D-glutamyl-peptide 5-glutamyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.1"^^xsd:string) "D-glutamyl transpeptidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-iditol 2-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.15"^^xsd:string) Annotation( "MetaCyc:D-IDITOL-2-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: D-iditol + NAD+ = D-sorbose + NADH."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "D-lactate-2-sulphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-lactate-2-sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.17"^^xsd:string) Annotation( "RHEA:20340"^^xsd:string) "Catalysis of the reaction: (R)-2-O-sulfolactate + H(2)O = (R)-lactate + H(+) + sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.17"^^xsd:string) "(S)-2-O-sulfolactate 2-sulfohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-lysine 5,6-aminomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.3.4"^^xsd:string) "adenosylcobalamin-dependent D-lysine 5,6-aminomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.3.4"^^xsd:string) "D-2,6-diaminohexanoate 5,6-aminomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.3.4"^^xsd:string) Annotation( "RHEA:18244"^^xsd:string) "Catalysis of the reaction: D-lysine = 2,5-diaminohexanoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.3.4"^^xsd:string) "D-alpha-lysine mutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.16"^^xsd:string) "D-lysopine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.16"^^xsd:string) "N2-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.16"^^xsd:string) "2-N-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.16"^^xsd:string) "lysopine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.16"^^xsd:string) Annotation( "RHEA:17628"^^xsd:string) "Catalysis of the reaction: D-lysopine + H(2)O + NADP(+) = L-lysine + H(+) + NADPH + pyruvate."^^xsd:string) AnnotationAssertion(rdfs:label "D-lysopine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.16"^^xsd:string) "D(+)-lysopine dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.1.15"^^xsd:string) Annotation( "RHEA:14204"^^xsd:string) "Catalysis of the reaction: D-lyxose = D-xylulose."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.15"^^xsd:string) "D-lyxose isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.15"^^xsd:string) "D-lyxose aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-lyxose ketol-isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.19"^^xsd:string) "NOS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.19"^^xsd:string) "nopaline synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.19"^^xsd:string) Annotation( "MetaCyc:D-NOPALINE-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O = L-arginine + 2-oxoglutarate + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.19"^^xsd:string) "nopaline dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-nopaline dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.19"^^xsd:string) "D-nopaline synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.19"^^xsd:string) "N2-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.19"^^xsd:string) "2-N-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-octopine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.11"^^xsd:string) "D-octopine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.11"^^xsd:string) "ODH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.11"^^xsd:string) "N2-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.11"^^xsd:string) "2-N-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.11"^^xsd:string) "octopine:NAD oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.11"^^xsd:string) "octopine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.11"^^xsd:string) Annotation( "MetaCyc:D-OCTOPINE-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O = L-arginine + pyruvate + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.3.5"^^xsd:string) "D-ornithine aminomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.3.5"^^xsd:string) Annotation( "RHEA:14896"^^xsd:string) "Catalysis of the reaction: D-ornithine = (2R,4S)-2,4-diaminopentanoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.3.5"^^xsd:string) "D-alpha-ornithine 5,4-aminomutase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-ornithine 4,5-aminomutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-pinitol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.142"^^xsd:string) "5D-5-O-methyl-chiro-inositol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.142"^^xsd:string) Annotation( "RHEA:20440"^^xsd:string) "Catalysis of the reaction: 5D-5-O-methyl-chiro-inositol + NADP(+) = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.142"^^xsd:string) "1D-3-O-methyl-chiro-inositol:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.21"^^xsd:string) "D-sorbitol:(acceptor) 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion( "D-sorbitol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.21"^^xsd:string) Annotation( "MetaCyc:D-SORBITOL-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: D-sorbitol + acceptor = L-sorbose + reduced acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "D-sorbitol dehydrogenase (acceptor) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.21"^^xsd:string) "D-sorbitol:acceptor 1-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.122"^^xsd:string) "L-fucose (D-arabinose) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.122"^^xsd:string) "D-threo-aldose:NAD+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.122"^^xsd:string) "(2S,3R)-aldose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.122"^^xsd:string) "dehydrogenase, L-fucose"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.122"^^xsd:string) "L-fucose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.122"^^xsd:string) Annotation( "MetaCyc:D-THREO-ALDOSE-1-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: a D-threo-aldose + NAD+ = a D-threo-aldono-1,5-lactone + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "D-threo-aldose 1-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.34"^^xsd:string) "acetyl-CoA-D-tryptophan-alpha-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.34"^^xsd:string) Annotation( "RHEA:10063"^^xsd:string) "Catalysis of the reaction: D-tryptophan + acetyl-CoA = N-acetyl-D-tryptophan + CoA + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.34"^^xsd:string) "D-tryptophan acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-tryptophan N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.34"^^xsd:string) "acetyl-CoA:D-tryptophan N-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.112"^^xsd:string) Annotation( "RHEA:23323"^^xsd:string) "Catalysis of the reaction: D-tryptophan + malonyl-CoA = N(2)-malonyl-D-tryptophan + CoA + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.112"^^xsd:string) "malonyl-CoA:D-tryptophan N-malonyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-tryptophan N-malonyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.179"^^xsd:string) "D-xylose:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-xylose 1-dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.179"^^xsd:string) Annotation( "RHEA:22003"^^xsd:string) "Catalysis of the reaction: D-xylose + NADP(+) = D-xylono-1,5-lactone + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.179"^^xsd:string) "D-xylose-NADP dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.179"^^xsd:string) "D-xylose:NADP+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.179"^^xsd:string) "D-xylose (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.175"^^xsd:string) "NAD-linked D-xylose dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-xylose 1-dehydrogenase (NAD) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.175"^^xsd:string) "(NAD)-linked D-xylose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.175"^^xsd:string) Annotation( "MetaCyc:D-XYLOSE-1-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: D-xylose + NAD+ = D-xylonolactone + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.175"^^xsd:string) "D-xylose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.175"^^xsd:string) "NAD-D-xylose"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.175"^^xsd:string) "NAD-D-xylose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.175"^^xsd:string) "D-xylose:NAD+ 1-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "dATP(dGTP)--DNA purine transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dATP(dGTP)-DNA purinetransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.99.1"^^xsd:string) "dATP(dGTP):depurinated-DNA purine transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.99.1"^^xsd:string) Annotation( "MetaCyc:DATPDGTP--DNA-PURINE-TRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: dATP + depurinated DNA = ribose triphosphate + DNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.12"^^xsd:string) Annotation( "MetaCyc:DCTP-PYROPHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: dCTP + H2O = dCMP + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "dCTP diphosphatase activity"^^xsd:string) AnnotationAssertion( "dCTP pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.12"^^xsd:string) "deoxycytidine-triphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.12"^^xsd:string) "deoxycytidine triphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.12"^^xsd:string) "dCTP nucleotidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.12"^^xsd:string) "dCTPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.12"^^xsd:string) "deoxy-CTPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.13"^^xsd:string) "ketogluconokinase activity"^^xsd:string) AnnotationAssertion( "dehydogluconokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.13"^^xsd:string) "ketogluconokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.13"^^xsd:string) "2-ketogluconokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.13"^^xsd:string) Annotation( "RHEA:10791"^^xsd:string) "Catalysis of the reaction: 2-dehydro-D-gluconate + ATP = 6-phospho-2-dehydro-D-gluconate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "dehydrogluconokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.13"^^xsd:string) "2-ketogluconate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.13"^^xsd:string) "ATP:2-dehydro-D-gluconate 6-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.34"^^xsd:string) "3-dehydro-L-gulonate carboxy-lyase (L-xylulose-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.34"^^xsd:string) Annotation( "RHEA:11087"^^xsd:string) "Catalysis of the reaction: 3-dehydro-L-gulonate + H(+) = L-xylulose + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.34"^^xsd:string) "3-keto-L-gulonate decarboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dehydro-L-gulonate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.34"^^xsd:string) "3-dehydro-L-gulonate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.34"^^xsd:string) "keto-L-gulonate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.4"^^xsd:string) "2-dehydro-D-gluconate:acceptor 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dehydrogluconate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.4"^^xsd:string) "2-oxogluconate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.4"^^xsd:string) "2-keto-D-gluconate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.4"^^xsd:string) "alpha-ketogluconate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.4"^^xsd:string) Annotation( "RHEA:12371"^^xsd:string) "Catalysis of the reaction: 2-dehydro-D-gluconate + A = 2,5-didehydro-D-gluconate + AH(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.4"^^xsd:string) "ketogluconate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "deoxycytidine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.14"^^xsd:string) Annotation( "MetaCyc:DEOXYCYTIDINE-DEAMINASE-RXN"^^xsd:string) "Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.14"^^xsd:string) "deoxycytidine aminohydrolase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.46"^^xsd:string) Annotation( "RHEA:15000"^^xsd:string) "Catalysis of the reaction: deoxylimonoate + H(2)O = deoxylimononate D-ring-lactone + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.46"^^xsd:string) "deoxylimonate A-ring-lactonohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "deoxylimonate A-ring-lactonase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.34"^^xsd:string) "deoxyribonucleotide 3'-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "deoxynucleotide 3'-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.34"^^xsd:string) Annotation( "MetaCyc:DEOXYNUCLEOTIDE-3-PHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: a deoxynucleoside 3'-phosphate + H2O = a deoxynucleoside + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.34"^^xsd:string) "3'-deoxynucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.34"^^xsd:string) "3'-deoxyribonucleotidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "deoxyuridine phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.23"^^xsd:string) "2'-deoxyuridine:phosphate 2-deoxy-alpha-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.23"^^xsd:string) "deoxyuridine:phosphate deoxy-alpha-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.23"^^xsd:string) Annotation( "MetaCyc:DEOXYURIDINE-PHOSPHORYLASE-RXN"^^xsd:string) "Catalysis of the reaction: deoxyuridine + phosphate = uracil + deoxy-D-ribose 1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.23"^^xsd:string) "deoxyuridine:phosphate deoxy-D-ribosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.3"^^xsd:string) "reductase kinase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.3"^^xsd:string) "hydroxymethylglutaryl coenzyme A reductase kinase kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.3"^^xsd:string) "reductase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.3"^^xsd:string) "hydroxymethylglutaryl coenzyme A reductase kinase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.3"^^xsd:string) "dephospho-reductase kinase kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dephospho-[reductase kinase] kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.3"^^xsd:string) "AMP-activated kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.3"^^xsd:string) "STK30"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.3"^^xsd:string) Annotation( "MetaCyc:DEPHOSPHO-REDUCTASE-KINASE-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + dephospho-[[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase] = ADP + [[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase]."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.3"^^xsd:string) "ATP:dephospho-{hydroxymethylglutaryl-CoA reductase (NADPH)kinase} phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.3"^^xsd:string) "AMP-activated protein kinase kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.5"^^xsd:string) "sucrose-1,6-alpha-glucan glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.5"^^xsd:string) Annotation( "MetaCyc:DEXTRANSUCRASE-RXN"^^xsd:string) "Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = D-fructose + 1,6-alpha-D-glucosyl(n+1)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.5"^^xsd:string) "SGE"^^xsd:string) AnnotationAssertion(rdfs:label "dextransucrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.5"^^xsd:string) "sucrose 6-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.5"^^xsd:string) "CEP"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.5"^^xsd:string) "sucrose:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.1.16"^^xsd:string) "meso-diaminopimelate D-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.16"^^xsd:string) "meso-diaminopimelate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.16"^^xsd:string) "meso-alpha,epsilon-diaminopimelate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.16"^^xsd:string) "meso-2,6-diaminoheptanedioate:NADP+ oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(rdfs:label "diaminopimelate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.16"^^xsd:string) Annotation( "RHEA:13564"^^xsd:string) "Catalysis of the reaction: meso-2,6-diaminopimelate + H(2)O + NADP(+) = L-2-amino-6-oxopimelate + H(+) + NADPH + NH(4)(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.23"^^xsd:string) Annotation( "MetaCyc:DICARBOXYLATE--COA-LIGASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + an omega-dicarboxylic acid = AMP + diphosphate + an omega-carboxyacyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.23"^^xsd:string) "omega-dicarboxylate:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "dicarboxylate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.23"^^xsd:string) "carboxylyl-CoA synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.16.1.2"^^xsd:string) "transferrin[Fe(II)]2:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.2"^^xsd:string) "diferric transferrin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.2"^^xsd:string) Annotation( "MetaCyc:DIFFERIC-TRANSFERRIN-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: transferrin[Fe2+]2 + NAD+ = transferrin[Fe3+]2 + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.2"^^xsd:string) "transferrin reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "diferric-transferrin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.2"^^xsd:string) "NADH diferric transferrin reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.134"^^xsd:string) "bis-D-fructose 2',1:2,1'-dianhydride fructohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "difructose-anhydride synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.134"^^xsd:string) "inulobiose hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.134"^^xsd:string) Annotation( "MetaCyc:DIFRUCTOSE-ANHYDRIDE-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: H2O + bis-D-fructose 2',1:2,1'-dianhydride = inulobiose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.20"^^xsd:string) Annotation( "RHEA:13600"^^xsd:string) "Catalysis of the reaction: 1,4-diguanidinobutane + H(2)O = agmatine + urea."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.20"^^xsd:string) "1,4-diguanidinobutane amidinohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "diguanidinobutanase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.160"^^xsd:string) "bunolol reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dihydrobunolol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.160"^^xsd:string) Annotation( "RHEA:15928"^^xsd:string) "Catalysis of the reaction: dihydrobunolol + NADP(+) = bunolol + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.160"^^xsd:string) "(+-)-5-[(tert-butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "dihydrocoumarin lipase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.35"^^xsd:string) "dihydrocoumarin lactonohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.35"^^xsd:string) Annotation( "RHEA:10363"^^xsd:string) "Catalysis of the reaction: 3,4-dihydrocoumarin + H(2)O = 3-(2-hydroxyphenyl)propanoate + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "dihydrocoumarin hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.3.7"^^xsd:string) Annotation( "RHEA:12387"^^xsd:string) "Catalysis of the reaction: 5,6-dihydrouracil + O(2) = H(2)O(2) + uracil."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.7"^^xsd:string) "5,6-dihydrouracil:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dihydrouracil oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.54"^^xsd:string) "dihydroxyfumarate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.54"^^xsd:string) Annotation( "RHEA:13848"^^xsd:string) "Catalysis of the reaction: dihydroxyfumarate + H(+) = 2-hydroxy-3-oxopropanoate + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.54"^^xsd:string) "dihydroxyfumarate carboxy-lyase (tartronate-semialdehyde-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "dihydroxyfumarate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "diiodophenylpyruvate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.96"^^xsd:string) Annotation( "RHEA:20296"^^xsd:string) "Catalysis of the reaction: 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD(+) = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.96"^^xsd:string) "KAR"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.96"^^xsd:string) "aromatic alpha-keto acid"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.96"^^xsd:string) "3-(3,5-diiodo-4-hydroxyphenyl)lactate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.96"^^xsd:string) "2-oxo acid reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "diiodotyrosine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.24"^^xsd:string) Annotation( "RHEA:19784"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + 3,5-diiodo-L-tyrosine = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.24"^^xsd:string) "3,5-diiodo-L-tyrosine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.24"^^xsd:string) "halogenated tyrosine transaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "diiodotyrosine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.24"^^xsd:string) "halogenated tyrosine aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.8.2"^^xsd:string) "dialkylfluorophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.2"^^xsd:string) "isopropylphosphorofluoridase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.2"^^xsd:string) "organophosphorus acid anhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.2"^^xsd:string) "DFPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.2"^^xsd:string) "tabunase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.2"^^xsd:string) "somanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.2"^^xsd:string) "diisopropylphosphofluoridase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.2"^^xsd:string) "OPAA activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.2"^^xsd:string) "diisopropyl-fluorophosphate fluorohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "diisopropyl-fluorophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.2"^^xsd:string) Annotation( "RHEA:24103"^^xsd:string) "Catalysis of the reaction: diisopropyl fluorophosphate + H(2)O = diisopropyl phosphate + 2 H(+) + hydrogen fluoride."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.2"^^xsd:string) "organophosphate acid anhydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.2"^^xsd:string) "diisopropylfluorophosphonate dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.2"^^xsd:string) "OPA anhydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.8.2"^^xsd:string) "diisopropyl phosphorofluoridate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.28"^^xsd:string) Annotation( "RHEA:11331"^^xsd:string) "Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + neryl diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.28"^^xsd:string) "dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallylcistransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dimethylallylcistransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.28"^^xsd:string) "neryl-diphosphate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.24"^^xsd:string) "microsomal oxidase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.24"^^xsd:string) "N,N-dimethylaniline-N-oxide formaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.24"^^xsd:string) "microsomal N-oxide dealkylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dimethylaniline-N-oxide aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.24"^^xsd:string) Annotation( "RHEA:19324"^^xsd:string) "Catalysis of the reaction: N,N-dimethylaniline N-oxide = N-methylaniline + formaldehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.24"^^xsd:string) "N,N-dimethylaniline-N-oxide formaldehyde-lyase (N-methylaniline-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.8.4"^^xsd:string) "N,N-dimethylglycine:acceptor oxidoreductase (demethylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.8.4"^^xsd:string) Annotation( "RHEA:22499"^^xsd:string) "Catalysis of the reaction: N,N-dimethylglycine + electron-transfer flavoprotein + H2O = sarcosine + formaldehyde + reduced electron-transfer flavoprotein."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.8.4"^^xsd:string) "N,N-dimethylglycine oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dimethylglycine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.8.4"^^xsd:string) "N,N-dimethylglycine:(acceptor) oxidoreductase (demethylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dimethylglycine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.10"^^xsd:string) "N,N-dimethylglycine:oxygen oxidoreductase (demethylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.10"^^xsd:string) Annotation( "RHEA:17080"^^xsd:string) "Catalysis of the reaction: N,N-dimethylglycine + H(2)O + O(2) = formaldehyde + H(2)O(2) + sarcosine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.84"^^xsd:string) Annotation( "RHEA:13324"^^xsd:string) "Catalysis of the reaction: (R)-3,3-dimethylmalate + NAD(+) = 3-methyl-2-oxobutanoate + CO(2) + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "dimethylmalate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.84"^^xsd:string) "beta,beta-dimethylmalate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.84"^^xsd:string) "(R)-3,3-dimethylmalate:NAD+ oxidoreductase (decarboxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dimethylmaleate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.85"^^xsd:string) "(2R,3S)-2,3-dimethylmalate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.85"^^xsd:string) Annotation( "RHEA:20256"^^xsd:string) "Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = dimethylmaleate + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.85"^^xsd:string) "(2R,3S)-2,3-dimethylmalate hydro-lyase (dimethylmaleate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.3"^^xsd:string) Annotation( "RHEA:19968"^^xsd:string) "Catalysis of the reaction: S,S-dimethyl-beta-propiothetin = acrylate + dimethyl sulfide + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.3"^^xsd:string) "S,S-dimethyl-beta-propiothetin dimethyl-sulfide-lyase (acrylate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "dimethylpropiothetin dethiomethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.3"^^xsd:string) "desulfhydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.3"^^xsd:string) "S,S-dimethyl-beta-propiothetin dimethyl-sulfide-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.24"^^xsd:string) "discadenine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.24"^^xsd:string) Annotation( "RHEA:19584"^^xsd:string) "Catalysis of the reaction: N(6)-dimethylallyladenine + S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + discadenine + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "discadenine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.24"^^xsd:string) "S-adenosyl-L-methionine:N6-(Delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferas"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.24"^^xsd:string) "S-adenosyl-L-methionine:6-N-(Delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.6.11"^^xsd:string) "N,6-O-disulfo-D-glucosamine 6-sulfohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "disulfoglucosamine-6-sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.11"^^xsd:string) "N-sulfoglucosamine-6-sulfatase activity"^^xsd:string) AnnotationAssertion( "disulphoglucosamine-6-sulphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.11"^^xsd:string) "6,N-disulfoglucosamine 6-O-sulfohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.11"^^xsd:string) Annotation( "RHEA:15520"^^xsd:string) "Catalysis of the reaction: N(2),6-disulfo-D-glucosamine + H(2)O = N-sulfo-D-glucosamine + H(+) + sulfate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.123"^^xsd:string) "palmitoyl-CoA:dolichol O-palmitoyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dolichol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.123"^^xsd:string) "acyl-CoA:dolichol acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.123"^^xsd:string) Annotation( "MetaCyc:DOLICHOL-O-ACYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: palmitoyl-CoA + dolichol = CoA + dolichyl palmitate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.51"^^xsd:string) "dolichyl-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.51"^^xsd:string) "dolichol monophosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dolichyl-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.51"^^xsd:string) "dolichol phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.51"^^xsd:string) "polyisoprenyl phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.51"^^xsd:string) "polyprenylphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.51"^^xsd:string) "dolichyl monophosphate phosphatase activity"^^xsd:string) AnnotationAssertion( "dolichyl pyrophosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.51"^^xsd:string) "dolichyl phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.51"^^xsd:string) "dolichol phosphatase activity"^^xsd:string) AnnotationAssertion( "Dol-P-P phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.51"^^xsd:string) Annotation( "MetaCyc:DOLICHYL-PHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: dolichyl phosphate + H2O = dolichol + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.51"^^xsd:string) "Dol-P phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.43"^^xsd:string) "dolichyl-diphosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.43"^^xsd:string) "dolichol diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.43"^^xsd:string) Annotation( "MetaCyc:DOLICHYLDIPHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: dolichyl diphosphate + H2O = dolichyl phosphate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.43"^^xsd:string) "dolichyl diphosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dolichyldiphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.43"^^xsd:string) "dolichyl pyrophosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.16"^^xsd:string) "ecdysone:oxygen 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.16"^^xsd:string) "beta-ecdysone oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.16"^^xsd:string) Annotation( "RHEA:11799"^^xsd:string) "Catalysis of the reaction: Ecdysone + O(2) = 3-dehydroecdysone + H(2)O(2)."^^xsd:string) AnnotationAssertion(rdfs:label "ecdysone oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.123"^^xsd:string) "oligoglycosylglucosylceramide glycohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.123"^^xsd:string) "EGCase activity"^^xsd:string) AnnotationAssertion(rdfs:label "endoglycosylceramidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.123"^^xsd:string) "endo-glucosylceramidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.123"^^xsd:string) Annotation( "MetaCyc:ENDOGLYCOSYLCERAMIDASE-RXN"^^xsd:string) "Catalysis of the reaction: H2O + oligoglycosylglucosylceramide = ceramide + oligoglycosylglucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.123"^^xsd:string) "glycosyl-N-acetyl-sphingosine 1,1-beta-D-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.123"^^xsd:string) "endoglycoceramidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.18"^^xsd:string) Annotation( "RHEA:16292"^^xsd:string) "Catalysis of the reaction: (1R,2S)-ephedrine + NAD(+) = (R)-2-methylimino-1-phenylpropan-1-ol + 2 H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.18"^^xsd:string) "(-)-ephedrine:NAD+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ephedrine dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.27"^^xsd:string) Annotation( "RHEA:20711"^^xsd:string) "Catalysis of the reaction: ATP + erythritol = D-erythritol 4-phosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.27"^^xsd:string) "erythritol kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.27"^^xsd:string) "ATP:erythritol 4-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "erythritol kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.94"^^xsd:string) "malonyl-CoA:propionyl-CoA malonyltransferase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.94"^^xsd:string) "erythronolide condensing enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "erythronolide synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.94"^^xsd:string) Annotation( "MetaCyc:ERYTHRONOLIDE-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: 6 malonyl-CoA + propionyl-CoA = 7 CoA + 6-deoxyerythronolide B."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "erythrulose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.162"^^xsd:string) "erythritol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.162"^^xsd:string) Annotation( "RHEA:18008"^^xsd:string) "Catalysis of the reaction: D-threitol + NADP(+) = D-erythrulose + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.162"^^xsd:string) "D-erythrulose reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.148"^^xsd:string) "17alpha-hydroxy steroid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.148"^^xsd:string) "17alpha-hydroxysteroid oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.148"^^xsd:string) Annotation( "MetaCyc:ESTRADIOL-17-ALPHA-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: estradiol-17-alpha + NAD(P)+ = estrone + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.148"^^xsd:string) "17alpha-hydroxy steroid oxidoreductase activity"^^xsd:string) AnnotationAssertion( "estradiol 17a-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.148"^^xsd:string) "17alpha-estradiol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.148"^^xsd:string) "estradiol 17alpha-dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "estradiol 17-alpha-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.148"^^xsd:string) "estradiol 17alpha-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.148"^^xsd:string) "17alpha-hydroxysteroid:NAD(P)+ 17-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "estradiol 6-beta-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.11"^^xsd:string) Annotation( "RHEA:19140"^^xsd:string) "Catalysis of the reaction: AH(2) + estradiol-17beta + O(2) = 6beta-hydroxyestradiol-17beta + A + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.11"^^xsd:string) "estradiol-17beta,hydrogen-donor:oxygen oxidoreductase (6beta-hydroxylating)"^^xsd:string) AnnotationAssertion( "estradiol 6b-monooxygenase activity"^^xsd:string) AnnotationAssertion( "estradiol 6b-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.11"^^xsd:string) "estradiol 6-beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.11"^^xsd:string) "estradiol 6beta-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.11"^^xsd:string) "estradiol 6beta-hydroxylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.3.8"^^xsd:string) "ethanolamine:oxygen oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.8"^^xsd:string) Annotation( "MetaCyc:ETHANOLAMINE-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: ethanolamine + H2O + O2 = glycolaldehyde + NH3 + H2O2."^^xsd:string) AnnotationAssertion(rdfs:label "ethanolamine oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.18"^^xsd:string) "flavin adenine dinucleotide pyrophosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "FAD diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.18"^^xsd:string) "riboflavin adenine dinucleotide pyrophosphatase activity"^^xsd:string) AnnotationAssertion( "FAD pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.18"^^xsd:string) Annotation( "MetaCyc:FAD-PYROPHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: FAD + H2O = AMP + FMN."^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "FAD pyrophosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.18"^^xsd:string) "FAD nucleotidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.18"^^xsd:string) "riboflavine adenine dinucleotide pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.18"^^xsd:string) "flavine adenine dinucleotide pyrophosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "farnesol 2-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.9"^^xsd:string) "2-trans,6-trans-farnesol 2-cis-trans-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.9"^^xsd:string) Annotation( "RHEA:13404"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesol = 2-cis,6-trans-farnesol."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.9"^^xsd:string) "farnesol isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.216"^^xsd:string) "2-trans,6-trans-farnesol:NADP+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.216"^^xsd:string) Annotation( "RHEA:14700"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesol + NADP(+) = 2-trans,6-trans-farnesal + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.216"^^xsd:string) "NADP-farnesol dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "farnesol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.216"^^xsd:string) "farnesol (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "farnesyl diphosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.18"^^xsd:string) "ATP:farnesyl-diphosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.18"^^xsd:string) Annotation( "RHEA:21547"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + ATP = 2-trans,6-trans-farnesyl triphosphate + ADP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.18"^^xsd:string) "farnesyl pyrophosphate kinase activity"^^xsd:string) AnnotationAssertion( "farnesyl-diphosphate kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.11.1.3"^^xsd:string) Annotation( "RHEA:23963"^^xsd:string) "Catalysis of the reaction: 2 H(2)O(2) + H(+) + palmitate = CO(2) + 3 H(2)O + pentadecanal."^^xsd:string) AnnotationAssertion( "fatty-acid peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.3"^^xsd:string) "hexadecanoate:hydrogen-peroxide oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "fatty acid peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.3"^^xsd:string) "long chain fatty acid peroxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.7.2"^^xsd:string) "assimilatory nitrate reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ferredoxin-nitrate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.7.2"^^xsd:string) "nitrate (ferredoxin) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.7.2"^^xsd:string) "assimilatory ferredoxin-nitrate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.7.2"^^xsd:string) "nitrite:ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.7.2"^^xsd:string) Annotation( "MetaCyc:FERREDOXIN--NITRATE-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: nitrite + H2O + 2 oxidized ferredoxin = nitrate + 2 reduced ferredoxin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.234"^^xsd:string) Annotation( "MetaCyc:FLAVANONE-4-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: (2S)-flavan-4-ol + NADP+ = (2S)-flavanone + NADPH."^^xsd:string) AnnotationAssertion( "flavonone 4-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.234"^^xsd:string) "(2S)-flavan-4-ol:NADP+ 4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "flavanone 4-reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.81"^^xsd:string) "UDP-glucose-luteolin beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.81"^^xsd:string) "uridine diphosphoglucose-apigenin 7-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.81"^^xsd:string) "UDPglucose-luteolin beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.81"^^xsd:string) "UDP-glucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.81"^^xsd:string) "UDPglucose-apigenin beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "flavone 7-O-beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.81"^^xsd:string) Annotation( "MetaCyc:FLAVONE-7-O-BETA-GLUCOSYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: UDP-glucose + 5,7,3',4'-tetrahydroxyflavone = UDP + 7-O-beta-D-glucosyl-5,7,3',4'-tetrahydroxyflavone."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.81"^^xsd:string) "UDPglucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "flavone 7-O-b-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.81"^^xsd:string) "UDP-glucose-apigenin beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.81"^^xsd:string) "uridine diphosphoglucose-luteolin glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "flavone apiosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.25"^^xsd:string) Annotation( "MetaCyc:FLAVONE-APIOSYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: UDP-apiose + 7-O-beta-D-glucosyl-5,7,4'-trihydroxyflavone = UDP + 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.25"^^xsd:string) "UDP-apiose:5,4'-dihydroxyflavone 7-O-beta-D-glucoside 2''-O-beta-D-apiofuranosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.25"^^xsd:string) "uridine diphosphoapiose-flavone apiosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.25"^^xsd:string) "UDP-apiose:7-O-(beta-D-glucosyl)-flavone apiosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "flavonol 3-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.91"^^xsd:string) "UDPglucose:flavonol 3-O-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.91"^^xsd:string) "UDP-glucose:flavonol 3-O-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.91"^^xsd:string) "UDP-glucose flavonol 3-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.91"^^xsd:string) "GTI"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.91"^^xsd:string) "UDPG:flavonoid-3-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.91"^^xsd:string) "UDP-glucose:flavonol 3-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.91"^^xsd:string) Annotation( "MetaCyc:FLAVONOL-3-O-GLUCOSYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 3-O-D-glucoside."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.91"^^xsd:string) "uridine diphosphoglucose-flavonol 3-O-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.25"^^xsd:string) Annotation( "RHEA:13456"^^xsd:string) "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin = adenosine 3',5'-diphosphate + H(+) + quercetin 3-sulfate."^^xsd:string) AnnotationAssertion( "flavonol 3-sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.25"^^xsd:string) Annotation( ) "3'-phosphoadenylyl-sulfate:quercetin 3-sulfotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "flavonol 3-sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.99.4"^^xsd:string) "nicotinoprotein aldehyde dismutase"^^xsd:string) AnnotationAssertion(rdfs:label "formaldehyde dismutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.99.4"^^xsd:string) "aldehyde dismutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.99.4"^^xsd:string) Annotation( "MetaCyc:FORMALDEHYDE-DISMUTASE-RXN"^^xsd:string) "Catalysis of the reaction: 2 formaldehyde + H2O = methanol + formate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.99.4"^^xsd:string) "cannizzanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.99.4"^^xsd:string) "formaldehyde:formaldehyde oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.2.1.3"^^xsd:string) "glycerone synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.3"^^xsd:string) "D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "formaldehyde transketolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.3"^^xsd:string) "dihydroxyacetone synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.3"^^xsd:string) "DHAS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.3"^^xsd:string) Annotation( "MetaCyc:FORMALDEHYDE-TRANSKETOLASE-RXN"^^xsd:string) "Catalysis of the reaction: D-xylulose 5-phosphate + formaldehyde = glyceraldehyde 3-phosphate + glycerone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.4.17"^^xsd:string) "dihydrofolate formyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.17"^^xsd:string) Annotation( "RHEA:24331"^^xsd:string) "Catalysis of the reaction: 7,8-dihydrofolate + ATP + formate = 10-formyldihydrofolate + ADP + H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.17"^^xsd:string) "formate:dihydrofolate ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "formate-dihydrofolate ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.17"^^xsd:string) "formyl dihydrofolate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.2.1"^^xsd:string) "formate:ferricytochrome-b1 oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "formate dehydrogenase (cytochrome) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.2.1"^^xsd:string) Annotation( "MetaCyc:FORMATE-DEHYDROGENASE-CYTOCHROME-RXN"^^xsd:string) "Catalysis of the reaction: formate + ferricytochrome b1 = CO2 + ferrocytochrome b1."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.2.1"^^xsd:string) "formate:cytochrome b1 oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "formate dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.43"^^xsd:string) "formate:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.43"^^xsd:string) "NADP-dependent formate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.43"^^xsd:string) Annotation( "RHEA:12003"^^xsd:string) "Catalysis of the reaction: formate + NADP(+) = CO(2) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.2.6"^^xsd:string) "ATP:formate phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "formate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.6"^^xsd:string) Annotation( "RHEA:16012"^^xsd:string) "Catalysis of the reaction: ATP + formate = ADP + formyl phosphate + H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.2.10"^^xsd:string) "formyl coenzyme A hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "formyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.10"^^xsd:string) Annotation( "RHEA:19744"^^xsd:string) "Catalysis of the reaction: formyl-CoA + H(2)O = CoA + formate + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "formylaspartate deformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.8"^^xsd:string) Annotation( "MetaCyc:FORMYLASPARTATE-DEFORMYLASE-RXN"^^xsd:string) "Catalysis of the reaction: N-formyl-L-aspartate + H2O = formate + L-aspartate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.8"^^xsd:string) "formylaspartic formylase (formylase I, formylase II)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.8"^^xsd:string) "N-formyl-L-aspartate amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.124"^^xsd:string) Annotation( "MetaCyc:FRUCTOSE-5-DEHYDROGENASE-NADP+-RXN"^^xsd:string) "Catalysis of the reaction: D-fructose + NADP+ = 5-dehydro-D-fructose + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.124"^^xsd:string) "5-ketofructose reductase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.124"^^xsd:string) "5-keto-D-fructose reductase (NADP+)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.124"^^xsd:string) "D-(-)fructose:(NADP+) 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.124"^^xsd:string) "fructose 5-(nicotinamide adenine dinucleotide phosphate) dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "fructose 5-dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.124"^^xsd:string) "5-ketofructose reductase (NADP)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.124"^^xsd:string) "D-fructose:NADP+ 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.124"^^xsd:string) "5-ketofructose reductase (NADP(+)) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.11"^^xsd:string) "fructose 5-dehydrogenase (acceptor)"^^xsd:string) AnnotationAssertion(rdfs:label "fructose 5-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.11"^^xsd:string) "D-fructose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.11"^^xsd:string) "D-fructose:acceptor 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.11"^^xsd:string) Annotation( "RHEA:22307"^^xsd:string) "Catalysis of the reaction: D-fructose + A = 5-dehydro-D-fructose + AH(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.11"^^xsd:string) "D-fructose:(acceptor) 5-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.22"^^xsd:string) Annotation( "MetaCyc:FRUCTOSE-6-PHOSPHATE-PHOSPHOKETOLASE-RXN"^^xsd:string) "Catalysis of the reaction: D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.22"^^xsd:string) "D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (phosphate-acetylating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "fructose-6-phosphate phosphoketolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.22"^^xsd:string) "D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (adding phosphate; acetyl-phosphate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.33"^^xsd:string) "(24R,24'R)-fucosterol-epoxide acetaldehyde-lyase (desmosterol-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.33"^^xsd:string) "(24R,24'R)-fucosterol-epoxide acetaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.33"^^xsd:string) Annotation( "RHEA:10887"^^xsd:string) "Catalysis of the reaction: (24R,24'R)-fucosterol epoxide = acetaldehyde + desmosterol."^^xsd:string) AnnotationAssertion(rdfs:label "fucosterol-epoxide lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.2.1.6"^^xsd:string) Annotation( "RHEA:21851"^^xsd:string) "Catalysis of the reaction: (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide = (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.6"^^xsd:string) "2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide cis-trans-isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "furylfuramide isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fusarinine-C ornithinesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.48"^^xsd:string) Annotation( "MetaCyc:FUSARININE-C-ORNITHINESTERASE-RXN"^^xsd:string) "Catalysis of the reaction: N5-acyl-L-ornithine ester + H2O = N5-acyl-L-ornithine + an alcohol."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.48"^^xsd:string) "ornithine esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.48"^^xsd:string) "N5-acyl-L-ornithine-ester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.48"^^xsd:string) "5-N-acyl-L-ornithine-ester hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.134"^^xsd:string) "mono-beta-D-galactosyldiacylglycerol:mono-beta-D-galactosyldiacylglycerol acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.134"^^xsd:string) Annotation( "MetaCyc:GALACTOLIPID-O-ACYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = acylmono-beta-D-galactosyl-diacylglycerol + mono-beta-D-galactosylacylglycerol."^^xsd:string) AnnotationAssertion(rdfs:label "galactolipid O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.134"^^xsd:string) "galactolipid:galactolipid acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.120"^^xsd:string) "D-galactose:NADP+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.120"^^xsd:string) Annotation( "MetaCyc:GALACTOSE-1-DEHYDROGENASE-NADP+-RXN"^^xsd:string) "Catalysis of the reaction: D-galactose + NADP+ = D-galactonolactone + NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "galactose 1-dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.120"^^xsd:string) "D-galactose dehydrogenase (NADP+)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "exo-D-galacturonase activity"^^xsd:string) AnnotationAssertion( "exo-polygalacturonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.67"^^xsd:string) "poly(1,4-alpha-D-galacturonide) galacturonohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.67"^^xsd:string) "poly(galacturonate) hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.67"^^xsd:string) Annotation( "MetaCyc:GALACTURAN-14-ALPHA-GALACTURONIDASE-RXN"^^xsd:string) "Catalysis of the reaction: [(1->4)-alpha-D-galacturonide](n) + H2O = [(1->4)-alpha-D-galacturonide](n-1) + D-galacturonate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.67"^^xsd:string) "exopolygalacturonase activity"^^xsd:string) AnnotationAssertion( "exopoly-D-galacturonase activity"^^xsd:string) AnnotationAssertion( "galacturan alpha-1,4-galacturonidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galacturan 1,4-alpha-galacturonidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.67"^^xsd:string) "exo-D-galacturonanase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.44"^^xsd:string) "galacturonokinase (phosphorylating) D-galacturonic acid kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.44"^^xsd:string) "ATP:D-galacturonate 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.44"^^xsd:string) Annotation( "RHEA:12968"^^xsd:string) "Catalysis of the reaction: alpha-D-galacturonate + ATP = 1-phospho-alpha-D-galacturonate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "galacturonokinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.136"^^xsd:string) "UDP-glucose:gallate beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.136"^^xsd:string) Annotation( "RHEA:15252"^^xsd:string) "Catalysis of the reaction: gallate + UDP-D-glucose = 1-O-galloyl-beta-D-glucose + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.136"^^xsd:string) "UDP-glucose-vanillate 1-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.136"^^xsd:string) "UDPglucose:vanillate 1-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.136"^^xsd:string) "UDPglucose:gallate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "gallate 1-beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.136"^^xsd:string) "UDPglucose:gallate beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "gallate 1-b-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.136"^^xsd:string) "UDPglucose-vanillate 1-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "g-glutamylhistamine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.18"^^xsd:string) Annotation( "MetaCyc:GAMMA-GLUTAMYLHISTAMINE-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: histamine + L-glutamate + ATP = N(alpha)-gamma-L-glutamylhistamine + products of ATP breakdown."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.18"^^xsd:string) "L-glutamate:histamine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.18"^^xsd:string) "gamma-GHA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.18"^^xsd:string) "gamma-glutaminylhistamine synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "gamma-glutamylhistamine synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.62"^^xsd:string) "UDPgalactose-ceramide galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.62"^^xsd:string) "UDP-galactose-GM2 galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.62"^^xsd:string) "GM1-synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.62"^^xsd:string) "uridine diphosphogalactose-ceramide galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.62"^^xsd:string) Annotation( "MetaCyc:GANGLIOSIDE-GALACTOSYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine = UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.62"^^xsd:string) "UDP-galactose:N-acetylgalactosaminyl-(N-acetylneuraminyl) galactosyl-glucosyl-ceramide galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.62"^^xsd:string) "uridine diphosphogalactose-GM2 galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.62"^^xsd:string) "UDP-galactose-GM2 ganglioside galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.62"^^xsd:string) "uridine diphosphate D-galactose:glycolipid galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.62"^^xsd:string) "UDP-galactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine beta-1,3-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ganglioside galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.62"^^xsd:string) "UDP galactose-LAC Tet-ceramide alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.62"^^xsd:string) "UDPgalactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine beta-1,3-D-galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.135"^^xsd:string) "GDP-6-deoxy-D-talose:NAD(P)+ 4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.135"^^xsd:string) "guanosine diphospho-6-deoxy-D-talose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.135"^^xsd:string) Annotation( "MetaCyc:GDP-6-DEOXY-D-TALOSE-4-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: GDP-6-deoxy-D-talose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-talose + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(rdfs:label "GDP-6-deoxy-D-talose 4-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.42"^^xsd:string) "guanosine diphosphoglucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.42"^^xsd:string) "guanosine diphosphate D-glucose glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.42"^^xsd:string) "GDPglucosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "GDP-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.42"^^xsd:string) Annotation( "RHEA:15052"^^xsd:string) "Catalysis of the reaction: GDP-D-glucose + H(2)O = D-glucose + GDP + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.42"^^xsd:string) "GDPglucose glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.42"^^xsd:string) "GDP-glucose glucohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.18"^^xsd:string) "GDPmannose 3,5-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.18"^^xsd:string) "guanosine 5'-diphosphate D-mannose:guanosine 5'-diphosphate L-galactose epimerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "GDP-mannose 3,5-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.18"^^xsd:string) "Catalysis of the reaction: GDP-mannose = GDP-L-galactose."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.18"^^xsd:string) "GDP-D-mannose:GDP-L-galactose epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.132"^^xsd:string) "guanosine diphospho-D-mannose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.132"^^xsd:string) "GDPmannose 6-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.132"^^xsd:string) Annotation( "RHEA:21731"^^xsd:string) "Catalysis of the reaction: GDP-alpha-D-mannose + H(2)O + 2 NAD(+) = GDP-D-mannuronate + 3 H(+) + 2 NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.132"^^xsd:string) "GDP mannose dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "GDP-mannose 6-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.132"^^xsd:string) "GDP-D-mannose:NAD+ 6-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.132"^^xsd:string) "guanosine diphosphomannose dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.36"^^xsd:string) "geissoschizine:NADP+ 4,21-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "geissoschizine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.36"^^xsd:string) Annotation( "RHEA:11379"^^xsd:string) "Catalysis of the reaction: geissoschizine + NADP(+) = 4,21-dehydrogeissoschizine + H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "gentamicin 2'-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.59"^^xsd:string) Annotation( "RHEA:24519"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + gentamicin C(1a) = N(2')-acetylgentamicin C(1a) + CoA + H(+). This is acetylation of the 2'-amino group of the 6-deoxy-6-aminoglucose ring."^^xsd:string) AnnotationAssertion(rdfs:label "aminoglycoside 2'-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion( "gentamycin 2'-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.59"^^xsd:string) "acetyl-CoA:gentamycin-C1a N2'-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.59"^^xsd:string) "acetyl-CoA:gentamicin-C1a N2'-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.59"^^xsd:string) "gentamicin acetyltransferase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.59"^^xsd:string) "gentamycin acetyltransferase II"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.4"^^xsd:string) "gentisate oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.4"^^xsd:string) "gentisate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.4"^^xsd:string) "2,5-dihydroxybenzoate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.4"^^xsd:string) Annotation( "RHEA:18240"^^xsd:string) "Catalysis of the reaction: 2,5-dihydroxybenzoate + O(2) = 3-maleylpyruvate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.4"^^xsd:string) "gentisate:oxygen 1,2-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.4"^^xsd:string) "gentisic acid oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "gentisate 1,2-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "gentisate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.62"^^xsd:string) "2,5-dihydroxybenzoate carboxy-lyase (hydroquinone-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.62"^^xsd:string) "2,5-dihydroxybenzoate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.62"^^xsd:string) Annotation( "RHEA:21315"^^xsd:string) "Catalysis of the reaction: 2,5-dihydroxybenzoate + H(+) = CO(2) + hydroquinone."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.62"^^xsd:string) "gentisate carboxy-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "geraniol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.183"^^xsd:string) Annotation( "MetaCyc:GERANIOL-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: geraniol + NADP+ = geranial + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.183"^^xsd:string) "geraniol:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "geranoyl-CoA carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.5"^^xsd:string) "geranoyl-CoA:carbon-dioxide ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.5"^^xsd:string) Annotation( "RHEA:17704"^^xsd:string) "Catalysis of the reaction: ATP + bicarbonate + geranoyl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + ADP + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.5"^^xsd:string) "geranyl-CoA carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.4.1.5"^^xsd:string) "geranoyl coenzyme A carboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.5.1.8"^^xsd:string) "bornyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.8"^^xsd:string) "(+)-bornyl-diphosphate lyase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.8"^^xsd:string) "(+)-bornylpyrophosphate cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.8"^^xsd:string) "bornyl pyrophosphate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "geranyl-diphosphate cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.8"^^xsd:string) "bornyl pyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.8"^^xsd:string) Annotation( "RHEA:18212"^^xsd:string) "Catalysis of the reaction: geranyl diphosphate = (2S)-bornyl diphosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.12"^^xsd:string) "(gibberellin-44),2-oxoglutarate:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "gibberellin-44 dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.12"^^xsd:string) "oxygenase, gibberellin A44 oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.12"^^xsd:string) "gibberellin A44 oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.12"^^xsd:string) Annotation( "MetaCyc:GIBBERELLIN-44-DIOXYGENASE-RXN"^^xsd:string) "Catalysis of the reaction: gibberellin 44 + 2-oxoglutarate + O2 = gibberellin 19 + succinate + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.12"^^xsd:string) "(gibberellin-44), 2-oxoglutarate:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.176"^^xsd:string) Annotation( "MetaCyc:GIBBERELLIN-BETA-GLUCOSYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: UDP-glucose + gibberellin = UDP + gibberellin 2-O-beta-D-glucoside."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.176"^^xsd:string) "uridine diphosphoglucose-gibberellate 3-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.176"^^xsd:string) "UDP-glucose:gibberellin 2-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "gibberellin b-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.176"^^xsd:string) "uridine diphosphoglucose-gibberellate 7-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.176"^^xsd:string) "UDPglucose:gibberellin 2-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "gibberellin beta-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.39"^^xsd:string) "D-gluconate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.39"^^xsd:string) Annotation( "RHEA:21615"^^xsd:string) "Catalysis of the reaction: D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.39"^^xsd:string) "D-gluconate hydro-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "gluconate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.39"^^xsd:string) "D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucosaminate ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.9"^^xsd:string) "D-glucosaminic acid dehydrase activity"^^xsd:string) AnnotationAssertion( "aminodeoxygluconate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.9"^^xsd:string) Annotation( "MetaCyc:GLUCOSAMINATE-AMMONIA-LYASE-RXN"^^xsd:string) "Catalysis of the reaction: D-glucosaminate = 2-dehydro-3-deoxy-D-gluconate + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.9"^^xsd:string) "acetylenemonocarboxylic acid hydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.9"^^xsd:string) "glucosaminic dehydrase activity"^^xsd:string) AnnotationAssertion( "aminodeoxygluconate ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.9"^^xsd:string) "D-glucosaminate ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.9"^^xsd:string) "2-amino-2-deoxy-D-gluconate hydro-lyase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.9"^^xsd:string) "D-glucosaminate ammonia-lyase (isomerizing; 2-dehydro-3-deoxy-D-gluconate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.9"^^xsd:string) "D-glucosaminate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.9"^^xsd:string) "2-amino-2-deoxy-D-gluconate ammonia-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.8"^^xsd:string) "glucosamine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.8"^^xsd:string) "aminodeoxyglucose kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.8"^^xsd:string) "ATP:D-glucosamine phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucosamine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.8"^^xsd:string) "ATP:2-amino-2-deoxy-D-glucose-6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.8"^^xsd:string) Annotation( "MetaCyc:GLUCOSAMINE-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + D-glucosamine = ADP + D-glucosamine phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.3"^^xsd:string) "acetyl-CoA:D-glucosamine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.3"^^xsd:string) "glucosamine acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.3"^^xsd:string) "glucosamine acetylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucosamine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.3"^^xsd:string) Annotation( "RHEA:21335"^^xsd:string) "Catalysis of the reaction: D-glucosamine + acetyl-CoA = N-acetyl-D-glucosamine + CoA + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.106"^^xsd:string) "3-phospho-D-glyceroyl-phosphate:D-glucose-1-phosphate 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.106"^^xsd:string) "glucose 1,6-diphosphate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucose-1,6-bisphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.106"^^xsd:string) "3-phospho-D-glyceroyl-phosphate:alpha-D-glucose-1-phosphate 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.106"^^xsd:string) "glucose-1,6-bisphosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.106"^^xsd:string) Annotation( "RHEA:16772"^^xsd:string) "Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate + alpha-D-glucose 1-phosphate = 3-phospho-D-glycerate + alpha-D-glucose 1,6-bisphosphate + H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.118"^^xsd:string) "D-glucose:NAD+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.118"^^xsd:string) Annotation( "MetaCyc:GLUCOSE-1-DEHYDROGENASE-NAD+-RXN"^^xsd:string) "Catalysis of the reaction: D-glucose + NAD+ = D-glucono-1,5-lactone + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "glucose 1-dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.118"^^xsd:string) "D-glucose:NAD oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.118"^^xsd:string) "D-aldohexose dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucose 1-dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.119"^^xsd:string) Annotation( "MetaCyc:GLUCOSE-1-DEHYDROGENASE-NADP+-RXN"^^xsd:string) "Catalysis of the reaction: D-glucose + NADP+ = D-glucono-1,4-lactone + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.119"^^xsd:string) "NADP-dependent glucose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.119"^^xsd:string) "nicotinamide adenine dinucleotide phosphate-linked aldohexose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.119"^^xsd:string) "NADP-linked aldohexose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.119"^^xsd:string) "D-glucose:NADP+ 1-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.47"^^xsd:string) "D-glucose dehydrogenase (NAD(P))"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.47"^^xsd:string) "hexose phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.47"^^xsd:string) "beta-D-glucose:NAD(P)+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.47"^^xsd:string) Annotation( "MetaCyc:GLUCOSE-1-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H."^^xsd:string) AnnotationAssertion(rdfs:label "glucose 1-dehydrogenase [NAD(P)] activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.41"^^xsd:string) "D-glucose-1-phosphate:D-glucose-1-phosphate 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.41"^^xsd:string) "glucose 1-phosphate transphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.41"^^xsd:string) "phosphodismutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.41"^^xsd:string) Annotation( "MetaCyc:GLUCOSE-1-PHOSPHATE-PHOSPHODISMUTASE-RXN"^^xsd:string) "Catalysis of the reaction: 2 D-glucose 1-phosphate = D-glucose + D-glucose 1,6-bisphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "glucose-1-phosphate phosphodismutase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucose-6-phosphate 1-epimerase activity"^^xsd:string) AnnotationAssertion( "glucose-6 phosphate 1-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.15"^^xsd:string) "D-glucose-6-phosphate 1-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.15"^^xsd:string) Annotation( "MetaCyc:GLUCOSE-6-PHOSPHATE-1-EPIMERASE-RXN"^^xsd:string) "Catalysis of the reaction: alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.19"^^xsd:string) "D-glucuronate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.19"^^xsd:string) "D-glucuronate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.19"^^xsd:string) "aldehyde reductase II activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-glucuronate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.19"^^xsd:string) "TPN-L-gulonate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.19"^^xsd:string) Annotation( "RHEA:14912"^^xsd:string) "Catalysis of the reaction: L-gulonate + NADP(+) = D-glucuronate + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.19"^^xsd:string) "NADP-L-gulonate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.19"^^xsd:string) "glucuronate dehydrogenase activity"^^xsd:string) AnnotationAssertion( "glucuronate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.43"^^xsd:string) "ATP:D-glucuronate 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.43"^^xsd:string) "glucurono-glucuronokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.43"^^xsd:string) Annotation( "RHEA:17008"^^xsd:string) "Catalysis of the reaction: D-glucuronate + ATP = 1-phospho-alpha-D-glucuronate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "glucuronokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.43"^^xsd:string) "glucuronokinase (phosphorylating)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucuronolactone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.20"^^xsd:string) Annotation( "RHEA:18928"^^xsd:string) "Catalysis of the reaction: L-gulono-1,4-lactone + NADP(+) = D-glucurono-3,6-lactone + H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.1.6"^^xsd:string) "N5-ethylglutamine synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamate-ethylamine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.6"^^xsd:string) Annotation( "RHEA:20528"^^xsd:string) "Catalysis of the reaction: L-glutamate + ATP + ethylamine = N(5)-ethyl-L-glutamine + ADP + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.6"^^xsd:string) "theanine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.6"^^xsd:string) "N5-ethyl-L-glutamine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.6"^^xsd:string) "L-glutamate:ethylamine ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.1.6"^^xsd:string) "N(5)-ethyl-L-glutamine synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutamate-methylamine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.12"^^xsd:string) Annotation( "RHEA:17120"^^xsd:string) "Catalysis of the reaction: L-glutamate + ATP + methylammonium = N(5)-methyl-L-glutamine + ADP + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.12"^^xsd:string) "L-glutamate:methylamine ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.12"^^xsd:string) "gamma-glutamylmethylamide synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutamate 1-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.13"^^xsd:string) Annotation( "RHEA:17220"^^xsd:string) "Catalysis of the reaction: L-glutamate + ATP = alpha-L-glutamyl phosphate + ADP + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.13"^^xsd:string) "ATP:L-glutamate 1-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-glutamine:pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.15"^^xsd:string) "L-glutamine transaminase L"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.15"^^xsd:string) "glutamine-oxo acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.15"^^xsd:string) "glutaminase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.15"^^xsd:string) "glutamine transaminase L activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.15"^^xsd:string) "glutamine-pyruvate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.15"^^xsd:string) "gamma-glutaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.15"^^xsd:string) "glutamine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.15"^^xsd:string) "glutamine-keto acid aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.15"^^xsd:string) "glutamine-alpha-keto acid transaminase activity"^^xsd:string) AnnotationAssertion( "glutamine--pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.15"^^xsd:string) "glutamine-alpha-keto acid transamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.15"^^xsd:string) Annotation( "RHEA:10403"^^xsd:string) "Catalysis of the reaction: L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.15"^^xsd:string) "glutamine--oxo-acid transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.68"^^xsd:string) Annotation( "MetaCyc:GLUTAMINE-N-ACYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: acyl-CoA + L-glutamine = CoA + N-acyl-L-glutamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.68"^^xsd:string) "acyl-CoA:L-glutamine N-acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamine N-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.14"^^xsd:string) "phenylacetyl-CoA:L-glutamine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamine N-phenylacetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.14"^^xsd:string) "glutamine phenylacetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.14"^^xsd:string) "phenylacetyl-CoA:L-glutamine alpha-N-phenylacetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.14"^^xsd:string) Annotation( "MetaCyc:GLUTAMINE-N-PHENYLACETYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: phenylacetyl-CoA + L-glutamine = CoA + alpha-N-phenylacetyl-L-glutamine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.6"^^xsd:string) Annotation( "RHEA:14172"^^xsd:string) "Catalysis of the reaction: ATP + CoA + glutarate = ADP + glutaryl-CoA + H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.6"^^xsd:string) "glutarate:CoA ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.6"^^xsd:string) "glutaryl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutarate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.6"^^xsd:string) "glutaryl-CoA synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutarate-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.20"^^xsd:string) Annotation( "MetaCyc:GLUTARATE-SEMIALDEHYDE-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: glutarate semialdehyde + NAD+ + H2O = glutarate + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.20"^^xsd:string) "glutarate semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.20"^^xsd:string) "glutarate-semialdehyde:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.3.3"^^xsd:string) Annotation( "RHEA:24115"^^xsd:string) "Catalysis of the reaction: 2 glutathione + O(2) = glutathione disulfide + H(2)O(2)."^^xsd:string) AnnotationAssertion(rdfs:label "glutathione oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.3.3"^^xsd:string) "glutathione:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glutathione thioesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.7"^^xsd:string) Annotation( "RHEA:22711"^^xsd:string) "Catalysis of the reaction: S-acylglutathione + H(2)O = a carboxylate + glutathione + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.7"^^xsd:string) "citryl-glutathione thioesterhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.7"^^xsd:string) "S-acylglutathione hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutathione thiolesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycerol-3-phosphate dehydrogenase [NAD(P)+] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.94"^^xsd:string) "glycerol 3-phosphate dehydrogenase (NAD(P)) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.94"^^xsd:string) "glycerol phosphate dehydrogenase (nicotinamide adenine dinucleotide (phosphate)) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.94"^^xsd:string) "glycerol 3-phosphate dehydrogenase (NADP) activity"^^xsd:string) AnnotationAssertion( "glycerol-3-phosphate dehydrogenase (NAD(P)+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.94"^^xsd:string) "sn-glycerol-3-phosphate:NAD(P)+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.94"^^xsd:string) "L-glycerol-3-phosphate:NAD(P) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.94"^^xsd:string) Annotation( "MetaCyc:GLYC3PDEHYDROGBIOSYN-RXN"^^xsd:string) "Catalysis of the reaction: sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.156"^^xsd:string) Annotation( "RHEA:12756"^^xsd:string) "Catalysis of the reaction: glycerol + NADP(+) = glycerone + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.156"^^xsd:string) "glycerol:NADP+ 2-oxidoreductase (glycerone-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "glycerol 2-dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.156"^^xsd:string) "dihydroxyacetone reductase (NADPH)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.156"^^xsd:string) "dihydroxyacetone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.156"^^xsd:string) "DHA oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.156"^^xsd:string) "dihydroxyacetone (reduced nicotinamide adenine dinucleotide phosphate) reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.19"^^xsd:string) "beta-glycerophosphate phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycerol-2-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.19"^^xsd:string) "beta-glycerophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.19"^^xsd:string) Annotation( "RHEA:13108"^^xsd:string) "Catalysis of the reaction: glycerol 2-phosphate + H(2)O = glycerol + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.19"^^xsd:string) "2-glycerophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.19"^^xsd:string) "glycerol-2-phosphate phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.22"^^xsd:string) "glycerol:acceptor 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycerol dehydrogenase (acceptor) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.22"^^xsd:string) Annotation( "RHEA:17496"^^xsd:string) "Catalysis of the reaction: A + glycerol = AH(2) + glycerone."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.22"^^xsd:string) "glycerol:(acceptor) 1-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glycerol dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycerol dehydrogenase [NADP+] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.72"^^xsd:string) "glycerol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.72"^^xsd:string) Annotation( "MetaCyc:GLYCEROL-DEHYDROGENASE-NADP+-RXN"^^xsd:string) "Catalysis of the reaction: glycerol + NADP+ = D-glyceraldehyde + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.53"^^xsd:string) "formononetin,NADPH:oxygen oxidoreductase (2'-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.53"^^xsd:string) Annotation( "MetaCyc:ISOFLAVONE-2-HYDROXYLASE-RXN"^^xsd:string) "Catalysis of the reaction: formononetin + NADPH + O2 = 2'-hydroxyformononetin + NADP+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "4'-methoxyisoflavone 2'-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.53"^^xsd:string) "isoflavone 2'-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.4"^^xsd:string) "glyoxylate-glutamate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.4"^^xsd:string) "glycine transaminase activity"^^xsd:string) AnnotationAssertion( "glycine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.4"^^xsd:string) "glutamic-glyoxylic transaminase activity"^^xsd:string) AnnotationAssertion( "L-glutamate:glyoxylate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.4"^^xsd:string) Annotation( "MetaCyc:GLYCINE-AMINOTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: glycine + 2-oxoglutarate = glyoxylate + L-glutamate."^^xsd:string) AnnotationAssertion(rdfs:label "glycine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.4"^^xsd:string) "glyoxylate-glutamic transaminase activity"^^xsd:string) AnnotationAssertion( "glutamate-glyoxylate transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.2.1"^^xsd:string) "glycine:ferricytochrome-c oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.2.1"^^xsd:string) "glycine-cytochrome c reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.2.1"^^xsd:string) Annotation( "MetaCyc:GLYCINE-DEHYDROGENASE-CYTOCHROME-RXN"^^xsd:string) "Catalysis of the reaction: glycine + H2O + 2 ferricytochrome c = glyoxylate + NH3 + 2 ferrocytochrome c."^^xsd:string) AnnotationAssertion(rdfs:label "glycine dehydrogenase (cytochrome) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.2.1"^^xsd:string) "reductase, glycine-cytochrome c"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.1.10"^^xsd:string) "glycine:NAD+ oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(rdfs:label "glycine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.10"^^xsd:string) Annotation( "MetaCyc:GLYCINE-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: glycine + H2O + NAD+ = glyoxylate + NH3 + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.13"^^xsd:string) "acyl-CoA:glycine N-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.13"^^xsd:string) Annotation( "MetaCyc:GLYCINE-N-ACYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: acyl-CoA + glycine = CoA + N-acylglycine."^^xsd:string) AnnotationAssertion(rdfs:label "glycine N-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.13"^^xsd:string) "glycine-N-acylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.13"^^xsd:string) "glycine acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.71"^^xsd:string) Annotation( "RHEA:18496"^^xsd:string) "Catalysis of the reaction: benzoyl-CoA + glycine = N-benzoylglycine + CoA + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.71"^^xsd:string) "benzoyl CoA-amino acid N-acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycine N-benzoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.71"^^xsd:string) "benzoyl-CoA:glycine N-benzoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.71"^^xsd:string) "benzoyl-CoA:glycine N-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.65"^^xsd:string) "bile acid-CoA:amino acid N-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.65"^^xsd:string) "glycine--taurine N-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.65"^^xsd:string) Annotation( "MetaCyc:GLYCINE-N-CHOLOYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: choloyl-CoA + glycine = CoA + glycocholate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.65"^^xsd:string) "BAT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.65"^^xsd:string) "cholyl-CoA:taurine N-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.65"^^xsd:string) "cholyl-CoA glycine-taurine N-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.65"^^xsd:string) "amino acid N-choloyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.65"^^xsd:string) "BACAT activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycine N-choloyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.65"^^xsd:string) "choloyl-CoA:glycine N-choloyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.26"^^xsd:string) "NADH-dependent glyoxylate reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glyoxylate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.26"^^xsd:string) Annotation( "MetaCyc:GLYCOLATE-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: glycolate + NAD+ = glyoxylate + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.26"^^xsd:string) "glyoxylic acid reductase activity"^^xsd:string) AnnotationAssertion( "glycolate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.142"^^xsd:string) Annotation( "MetaCyc:GLYCOPROTEIN-O-FATTY-ACYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: palmitoyl-CoA + mucus glycoprotein = CoA + O-palmitoylglycoprotein."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.142"^^xsd:string) "fatty-acyl-CoA:mucus-glycoprotein fatty-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.142"^^xsd:string) "protein acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycoprotein O-fatty-acyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "glycosulphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.3"^^xsd:string) "glucosulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.3"^^xsd:string) Annotation( "RHEA:19148"^^xsd:string) "Catalysis of the reaction: D-glucose 6-sulfate + H(2)O = D-glucose + H(+) + sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.3"^^xsd:string) "sugar-sulfate sulfohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycosulfatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.128"^^xsd:string) "glycyrrhizinate glucuronosylhydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycyrrhizinate beta-glucuronidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.128"^^xsd:string) "glycyrrhizin hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.128"^^xsd:string) "glycyrrhizinic acid hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.128"^^xsd:string) "glycyrrhizin beta-hydrolase activity"^^xsd:string) AnnotationAssertion( "glycyrrhizinate b-glucuronidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.128"^^xsd:string) Annotation( "RHEA:17372"^^xsd:string) "Catalysis of the reaction: glycyrrhizate + H(2)O = 2-(beta-D-glucuronosyl)-D-glucuronate + glycyrrhetinate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glyoxylate dehydrogenase (acylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.17"^^xsd:string) "glyoxylate:NADP+ oxidoreductase (CoA-oxalylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.17"^^xsd:string) Annotation( "RHEA:21027"^^xsd:string) "Catalysis of the reaction: CoA + glyoxylate + NADP(+) = H(+) + NADPH + oxalyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.3.5"^^xsd:string) "glyoxylate:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.5"^^xsd:string) Annotation( "RHEA:14840"^^xsd:string) "Catalysis of the reaction: glyoxylate + H(2)O + O(2) = H(2)O(2) + H(+) + oxalate."^^xsd:string) AnnotationAssertion(rdfs:label "glyoxylate oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.2"^^xsd:string) "glycocyaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.2"^^xsd:string) Annotation( "RHEA:23271"^^xsd:string) "Catalysis of the reaction: guanidinoacetate + H(2)O = glycine + urea."^^xsd:string) AnnotationAssertion(rdfs:label "guanidinoacetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.2"^^xsd:string) "guanidinoacetate amidinohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.7"^^xsd:string) "guanidinobutyrate ureahydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.7"^^xsd:string) "gamma-guanidobutyrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.7"^^xsd:string) "4-guanidinobutanoate amidinohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.7"^^xsd:string) "GBH"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.7"^^xsd:string) "gamma-guanidinobutyrate amidinohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "guanidinobutyrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.7"^^xsd:string) Annotation( "RHEA:19504"^^xsd:string) "Catalysis of the reaction: 4-guanidinobutanoate + H(2)O = 4-aminobutanoate + urea."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.7"^^xsd:string) "G-base activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.7"^^xsd:string) "4-guanidinobutyrate amidinobutyrase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.17"^^xsd:string) "3-guanidinopropanoate amidinopropionase activity"^^xsd:string) AnnotationAssertion(rdfs:label "guanidinopropionase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.17"^^xsd:string) Annotation( "RHEA:16032"^^xsd:string) "Catalysis of the reaction: 3-guanidinopropanoate + H(2)O = beta-alanine + urea."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.17"^^xsd:string) "GPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.17"^^xsd:string) "GPH"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.3.1"^^xsd:string) "ATP:guanidinoacetate N-phosphotransferase activity"^^xsd:string) AnnotationAssertion( "guanidoacetate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.1"^^xsd:string) Annotation( "RHEA:14148"^^xsd:string) "Catalysis of the reaction: ATP + guanidinoacetate = ADP + 2 H(+) + phosphoguanidinoacetate."^^xsd:string) AnnotationAssertion(rdfs:label "guanidinoacetate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.1"^^xsd:string) "glycocyamine kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.15"^^xsd:string) "guanosine aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.15"^^xsd:string) "guanosine aminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "guanosine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.15"^^xsd:string) Annotation( "MetaCyc:GUANOSINE-DEAMINASE-RXN"^^xsd:string) "Catalysis of the reaction: guanosine + H2O = xanthosine + NH3."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.15"^^xsd:string) Annotation( "MetaCyc:GUANPHOSPHOR-RXN"^^xsd:string) "Catalysis of the reaction: guanosine + phosphate = guanine + D-ribose 1-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "guanosine phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.15"^^xsd:string) "guanosine:phosphate alpha-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.15"^^xsd:string) "guanosine:phosphate D-ribosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.102"^^xsd:string) "hamamelose kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.102"^^xsd:string) "ATP:D-hamamelose 2'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.102"^^xsd:string) Annotation( "RHEA:22799"^^xsd:string) "Catalysis of the reaction: D-hamamelose + ATP = D-hamamelose 2'-phosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.102"^^xsd:string) "ATP/hamamelose 2'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hamamelose kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.102"^^xsd:string) "hamamelosekinase (ATP: hamamelose 2'-phosphotransferase)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hepoxilin-epoxide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.7"^^xsd:string) "(5Z,9E,14Z)-(8xi,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.7"^^xsd:string) "hepoxylin hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.7"^^xsd:string) Annotation( "MetaCyc:HEPOXILIN-EPOXIDE-HYDROLASE-RXN"^^xsd:string) "Catalysis of the reaction: (5Z,9E,14Z)-(8x,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate + H2O = (5Z,9E,14Z)-(8x,11x,12S)-8,11,12-trihydroxyicosa-5,9,14-trienoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.7"^^xsd:string) "hepoxilin epoxide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.7"^^xsd:string) "hepoxilin A3 hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.7"^^xsd:string) "hepoxilin A(3) hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.164"^^xsd:string) Annotation( "MetaCyc:HEXADECANOL-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: hexadecanol + NAD+ = hexadecanal + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.164"^^xsd:string) "hexadecanol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hexadecanol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hexose oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.5"^^xsd:string) Annotation( "MetaCyc:HEXOSE-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: hexose + O2 = aldono-1,5-lactone + H202."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.5"^^xsd:string) "D-hexose:oxygen 1-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.32"^^xsd:string) "N-benzoylamino-acid amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.32"^^xsd:string) Annotation( "RHEA:10427"^^xsd:string) "Catalysis of the reaction: N-benzoylglycine + H(2)O = benzoate + glycine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.32"^^xsd:string) "hippuricase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.32"^^xsd:string) "benzoylglycine amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hippurate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.33"^^xsd:string) Annotation( "RHEA:24599"^^xsd:string) "Catalysis of the reaction: L-histidine + acetyl-CoA = N(alpha)-acetyl-L-histidine + CoA + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.33"^^xsd:string) "histidine acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "histidine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.33"^^xsd:string) "acetyl-CoA:L-histidine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.33"^^xsd:string) "acetylhistidine synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.2"^^xsd:string) "L-homocysteine hydrogen-sulfide-lyase (deaminating; 2-oxobutanoate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.2"^^xsd:string) "homocysteine desulfurase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.2"^^xsd:string) Annotation( "MetaCyc:HOMOCYSTEINE-DESULFHYDRASE-RXN"^^xsd:string) "Catalysis of the reaction: L-homocysteine + H2O = sulfide + NH3 + 2-oxobutanoate."^^xsd:string) AnnotationAssertion(rdfs:label "homocysteine desulfhydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.2"^^xsd:string) "L-homocysteine hydrogen-sulfide-lyase (deaminating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.23"^^xsd:string) "homoglutathione synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.23"^^xsd:string) Annotation( "RHEA:17996"^^xsd:string) "Catalysis of the reaction: beta-alanine + L-gamma-glutamyl-L-cysteine + ATP = gamma-L-glutamyl-L-cysteinyl-beta-alanine + ADP + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.23"^^xsd:string) "beta-alanine specific hGSH synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.23"^^xsd:string) "gamma-L-glutamyl-L-cysteine:beta-alanine ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "homoglutathione synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.12.1.2"^^xsd:string) "NAD-linked hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.1.2"^^xsd:string) "hydrogen:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.1.2"^^xsd:string) "H2:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.1.2"^^xsd:string) "bidirectional hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.1.2"^^xsd:string) "H(2):NAD(+) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.1.2"^^xsd:string) Annotation( "MetaCyc:HYDROGEN-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: H2 + NAD+ = H+ + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "hydrogen dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.1.2"^^xsd:string) "hydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.10"^^xsd:string) "acetyl-CoA:hydrogen-sulfide S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydrogen-sulfide S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.10"^^xsd:string) Annotation( "RHEA:16628"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + S(2-) = CoA + thioacetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.10"^^xsd:string) "hydrogen-sulfide acetyltransferase activity"^^xsd:string) AnnotationAssertion( "hydrogen-sulphide S-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.92"^^xsd:string) "(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase [(9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate-forming]"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.92"^^xsd:string) Annotation( "MetaCyc:HYDROPEROXIDE-DEHYDRATASE-RXN"^^xsd:string) "Catalysis of the reaction: (9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate = (9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.92"^^xsd:string) "linoleate hydroperoxide isomerase"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.92"^^xsd:string) "linoleic acid hydroperoxide isomerase"^^xsd:string) AnnotationAssertion(rdfs:label "hydroperoxide dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.92"^^xsd:string) "HPI"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.92"^^xsd:string) "(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.92"^^xsd:string) "hydroperoxide isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroxyacid-oxoacid transhydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.24"^^xsd:string) "(S)-3-hydroxybutanoate:2-oxoglutarate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.24"^^xsd:string) "transhydrogenase, hydroxy acid-oxo acid"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.24"^^xsd:string) Annotation( "MetaCyc:HYDROXYACID-OXOACID-TRANSHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroxybutyrate-dimer hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.22"^^xsd:string) "D-(-)-3-hydroxybutyrate-dimer hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.22"^^xsd:string) "(R)-3-((R)-3-hydroxybutanoyloxy)butanoate hydroxybutanoylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.22"^^xsd:string) Annotation( "RHEA:10175"^^xsd:string) "Catalysis of the reaction: (R)-3-[(R)-3-hydroxybutanoyloxy]butanoate + H(2)O = 2 (R)-3-hydroxybutanoate + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.16"^^xsd:string) Annotation( "RHEA:14076"^^xsd:string) "Catalysis of the reaction: 3-hydroxy-L-glutamate + H(+) = 4-amino-3-hydroxybutanoate + CO(2)."^^xsd:string) AnnotationAssertion(rdfs:label "hydroxyglutamate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.16"^^xsd:string) "3-hydroxy-L-glutamate 1-carboxy-lyase (4-amino-3-hydroxybutanoate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.16"^^xsd:string) "3-hydroxy-L-glutamate 1-carboxy-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.3.4"^^xsd:string) "hydroxylamine oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.3.4"^^xsd:string) "HAO"^^xsd:string) AnnotationAssertion(rdfs:label "hydroxylamine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.3.4"^^xsd:string) Annotation( "RHEA:19972"^^xsd:string) "Catalysis of the reaction: hydroxylamine + O(2) = H(2)O + H(+) + nitrite."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.3.4"^^xsd:string) "hydroxylamine:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroxylysine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.81"^^xsd:string) Annotation( "RHEA:19052"^^xsd:string) "Catalysis of the reaction: erythro-5-hydroxy-L-lysine + GTP = 5-phosphonooxy-L-lysine + GDP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.81"^^xsd:string) "guanosine triphosphate:5-hydroxy-L-lysine O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.81"^^xsd:string) "hydroxylysine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.81"^^xsd:string) "GTP:5-hydroxy-L-lysine O-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroxymalonate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.167"^^xsd:string) Annotation( "RHEA:11287"^^xsd:string) "Catalysis of the reaction: hydroxymalonate + NAD(+) = H(+) + NADH + oxomalonate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.167"^^xsd:string) "hydroxymalonate:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.2.5"^^xsd:string) "hydroxymethylglutaryl coenzyme A deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.5"^^xsd:string) "hydroxymethylglutaryl coenzyme A hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.5"^^xsd:string) "beta-hydroxy-beta-methylglutaryl coenzyme A deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.5"^^xsd:string) "(S)-3-hydroxy-3-methylglutaryl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydroxymethylglutaryl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.5"^^xsd:string) "beta-hydroxy-beta-methylglutaryl coenzyme A hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.5"^^xsd:string) Annotation( "RHEA:16308"^^xsd:string) "Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA + H(2)O = 3-hydroxy-3-methylglutarate + CoA + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.5"^^xsd:string) "3-hydroxy-3-methylglutaryl-CoA hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.237"^^xsd:string) "4-hydroxyphenyllactate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.237"^^xsd:string) "HPRP"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.237"^^xsd:string) Annotation( "MetaCyc:HYDROXYPHENYLPYRUVATE-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: 3-(4-hydroxyphenyl)lactate + NAD+ = 3-(4-hydroxyphenyl)pyruvate + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "hydroxyphenylpyruvate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroxyphytanate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.27"^^xsd:string) "L-2-hydroxyphytanate:oxygen 2-oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.27"^^xsd:string) Annotation( "RHEA:21683"^^xsd:string) "Catalysis of the reaction: (2S)-2-hydroxyphytanate + O(2) = 2-oxophytanate + H(2)O(2)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.40"^^xsd:string) Annotation( "RHEA:20564"^^xsd:string) "Catalysis of the reaction: 3-hydroxypyruvate + H(+) = CO(2) + glycolaldehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.40"^^xsd:string) "hydroxypyruvate carboxy-lyase (glycolaldehyde-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.40"^^xsd:string) "hydroxypyruvate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydroxypyruvate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.11"^^xsd:string) "L-hyoscyamine,2-oxoglutarate:oxygen oxidoreductase ((6S)-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.11"^^xsd:string) "hyoscyamine (6S)-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.11"^^xsd:string) "hyoscyamine 6beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.11"^^xsd:string) "hyoscyamine 6-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.11"^^xsd:string) Annotation( "RHEA:12632"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + L-hyoscyamine + O(2) = (6S)-6-hydroxyhyoscyamine + CO(2) + succinate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.11"^^xsd:string) "hyoscyamine 6-beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.11"^^xsd:string) "hyoscyamine 6beta-dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hyoscyamine (6S)-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.1.5"^^xsd:string) Annotation( "RHEA:19340"^^xsd:string) "Catalysis of the reaction: 2 hydroxylamine + 2 NAD(+) = 2 H(+) + hyponitrous acid + 2 NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.5"^^xsd:string) "NADH2:hyponitrite oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.5"^^xsd:string) "hydroxylamine:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.5"^^xsd:string) "NADH:hyponitrite oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hyponitrite reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "isoflavone 3'-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.52"^^xsd:string) "isoflavone 3'-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.52"^^xsd:string) Annotation( "MetaCyc:ISOFLAVONE-3'-HYDROXYLASE-RXN"^^xsd:string) "Catalysis of the reaction: formononetin + NADPH + O2 = calycosin + NADP+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.52"^^xsd:string) "formononetin,NADPH:oxygen oxidoreductase (3'-hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.72"^^xsd:string) "E4P dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.72"^^xsd:string) "E4PDH"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.72"^^xsd:string) "D-erythrose 4-phosphate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.72"^^xsd:string) "erythrose 4-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.72"^^xsd:string) Annotation( "RHEA:12059"^^xsd:string) "Catalysis of the reaction: D-erythrose 4-phosphate + H(2)O + NAD(+) = 4-phospho-D-erythronate + 2 H(+) + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "erythrose-4-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.72"^^xsd:string) "GapB"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.72"^^xsd:string) "Epd dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "receptor agonist activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_signaling"^^xsd:string) "receptor ligand activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacts with receptors such that the proportion of receptors in the active form is increased."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "receptor antagonist activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_signaling"^^xsd:string) "receptor ligand activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ceb"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacts with receptors to reduce the action of another ligand, the agonist."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "CCR chemokine receptor binding"^^xsd:string) AnnotationAssertion( "beta chemokine receptor ligand"^^xsd:string) AnnotationAssertion( "CCR chemokine receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a CCR chemokine receptor."^^xsd:string) AnnotationAssertion( "beta chemokine receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) "Interacting selectively and non-covalently with the 5' untranslated region of an mRNA molecule."^^xsd:string) AnnotationAssertion( "mRNA 5' UTR binding"^^xsd:string) AnnotationAssertion(rdfs:label "mRNA 5'-UTR binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) "Interacting selectively and non-covalently with any simple or complex galacturonan. Galacturonan is any glycan composed solely of galacturonic acid residues, a specific type of glycuronan, and a constituent of some pectins."^^xsd:string) AnnotationAssertion(rdfs:label "galacturonan binding"^^xsd:string) AnnotationAssertion( "polygalacturonide binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:35381"^^xsd:string) Annotation( "GOC:jid"^^xsd:string) "Interacting selectively and non-covalently with any monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides."^^xsd:string) AnnotationAssertion(rdfs:label "monosaccharide binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "disaccharide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) "Interacting selectively and non-covalently with any disaccharide. Disaccharides are sugars composed of two monosaccharide units."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "trisaccharide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) "Interacting selectively and non-covalently with any trisaccharide. Trisaccharides are sugars composed of three monosaccharide units."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "galacturonic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:33812"^^xsd:string) Annotation( "GOC:jid"^^xsd:string) "Interacting selectively and non-covalently with any galacturonate. Galacturonate is the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group."^^xsd:string) AnnotationAssertion(rdfs:label "galacturonate binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate."^^xsd:string) AnnotationAssertion(rdfs:label "cofactor binding"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "quinone binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ubiquinone binding"^^xsd:string) AnnotationAssertion( "coenzyme Q binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) Annotation( "ISBN:0582227089"^^xsd:string) "Interacting selectively and non-covalently with ubiquinone, a quinone derivative with a tail of isoprene units."^^xsd:string) AnnotationAssertion( "coenzyme Q6 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.35"^^xsd:string) "UDPglucuronate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.35"^^xsd:string) "UDP-D-glucuronate carboxy-lyase (UDP-D-xylose-forming)"^^xsd:string) AnnotationAssertion( "UDP-glucuronic acid decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.35"^^xsd:string) "UDP-D-glucuronate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-glucuronate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.35"^^xsd:string) "uridine-diphosphoglucuronate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.35"^^xsd:string) Annotation( "RHEA:23919"^^xsd:string) "Catalysis of the reaction: H(+) + UDP-alpha-D-glucuronate = CO(2) + UDP-alpha-D-xylose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "hexaprenyl pyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.-"^^xsd:string) "all-trans-pentaprenyl-diphosphate:isopentenyl-diphosphate pentaprenyltranstransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:22635"^^xsd:string) "Catalysis of the reaction: all-trans-pentaprenyl diphosphate + isopentenyl diphosphate = all-trans-hexaprenyl diphosphate + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.-"^^xsd:string) "hexaprenyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.-"^^xsd:string) "all-trans-hexaprenyl-diphosphate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trans-pentaprenyltranstransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "calcium- and calmodulin-regulated cGMP-specific phosphodiesterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity"^^xsd:string) AnnotationAssertion( "calcium/calmodulin-regulated cGMP-specific phosphodiesterase activity"^^xsd:string) AnnotationAssertion( "calcium- and calmodulin-regulated cGMP phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) "Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. The reaction is calmodulin and calcium-sensitive."^^xsd:string) AnnotationAssertion( "calcium- and calmodulin-regulated cyclic-GMP phosphodiesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tau protein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) "Interacting selectively and non-covalently with tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "activin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with activin, a dimer of inhibin-beta subunits."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phytanoyl-CoA dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.18"^^xsd:string) "phytanoyl-CoA 2 oxoglutarate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.18"^^xsd:string) "phytanoyl-CoA hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.18"^^xsd:string) "phytanoyl-CoA, 2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.18"^^xsd:string) "phytanoyl-CoA alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.18"^^xsd:string) "phytanoyl-CoA 2-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.18"^^xsd:string) Annotation( "RHEA:16068"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + O(2) + phytanoyl-CoA = 2-hydroxyphytanoyl-CoA + CO(2) + succinate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) Annotation( "PMID:10556837"^^xsd:string) "Interacting selectively and non-covalently with a the CXCR3 chemokine receptor."^^xsd:string) AnnotationAssertion(rdfs:label "CXCR3 chemokine receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "high affinity phosphate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) Annotation( "PMID:8709965"^^xsd:string) "Catalysis of the transfer of phosphate from one side of the membrane to the other. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) "Catalysis of the cleavage of a flap structure in DNA, but not other DNA structures; processes the ends of Okazaki fragments in lagging strand DNA synthesis."^^xsd:string) AnnotationAssertion(rdfs:label "flap endonuclease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) Annotation( "PMID:10635319"^^xsd:string) "Catalysis of the cleavage of a 3' flap structure in DNA, but not other DNA structures; processes the 3' ends of Okazaki fragments in lagging strand DNA synthesis."^^xsd:string) AnnotationAssertion( "3' flap endonuclease activity"^^xsd:string) AnnotationAssertion(rdfs:label "3'-flap endonuclease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-ketoglucose-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:KETOGLUCOSE-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: NADP+ + 3-dehydro-alpha-D-glucose = NADPH + alpha-D-glucose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methionine adenosyltransferase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.6"^^xsd:string) Annotation( "GOC:jid"^^xsd:string) Annotation( "PMID:10644686"^^xsd:string) "Modulates the activity of methionine adenosyltransferase."^^xsd:string) AnnotationAssertion( "MAT regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "mitogen-activated protein kinase p38 binding"^^xsd:string) AnnotationAssertion( "MAPK p38 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) Annotation( "PMID:17827184"^^xsd:string) "Interacting selectively and non-covalently with mitogen-activated protein kinase p38, an enzyme that catalyzes the transfer of phosphate from ATP to hydroxyl side chains on proteins in response to mitogen activation."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcium-dependent protein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) Annotation( "PMID:10485905"^^xsd:string) "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ferredoxin-nitrite reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.7.1"^^xsd:string) "ammonia:ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.7.1"^^xsd:string) Annotation( "GOC:jid"^^xsd:string) "Catalysis of the reaction: NH3 + 2 H2O + 6 oxidized ferredoxin = nitrite + 6 reduced ferredoxin + 7 H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ebc"^^xsd:string) Annotation( "PMID:11702775"^^xsd:string) "Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases."^^xsd:string) AnnotationAssertion(rdfs:label "Rac GTPase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "BDNF binding"^^xsd:string) AnnotationAssertion(rdfs:label "brain-derived neurotrophic factor binding"^^xsd:string) AnnotationAssertion( "neurotrophin TRKB receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dgh"^^xsd:string) "Interacting selectively and non-covalently with brain-derived neurotrophic factor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dgh"^^xsd:string) "Interacting selectively and non-covalently with nerve growth factor (NGF)."^^xsd:string) AnnotationAssertion(Annotation( "PR:000011194"^^xsd:string) "NGF binding"^^xsd:string) AnnotationAssertion( "neurotrophin TRKA receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "nerve growth factor binding"^^xsd:string) AnnotationAssertion(Annotation( "PR:000011194"^^xsd:string) "beta-nerve growth factor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dgh"^^xsd:string) "Interacting selectively and non-covalently with platelet-derived growth factor."^^xsd:string) AnnotationAssertion(rdfs:label "platelet-derived growth factor binding"^^xsd:string) AnnotationAssertion( "PDGF binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dgh"^^xsd:string) "Interacting selectively and non-covalently with epidermal growth factor."^^xsd:string) AnnotationAssertion( "EGF binding"^^xsd:string) AnnotationAssertion(rdfs:label "epidermal growth factor binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.81"^^xsd:string) "L-threonine O-3-phosphate carboxy-lyase [(R)-1-aminopropan-2-yl-phosphate-forming]"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.81"^^xsd:string) "CobD"^^xsd:string) AnnotationAssertion( "L-threonine-O-3-phosphate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.81"^^xsd:string) Annotation( "RHEA:11495"^^xsd:string) "Catalysis of the reaction: O-phospho-L-threonine + H(+) = (R)-1-aminopropan-2-yl phosphate + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.81"^^xsd:string) "L-threonine O-3-phosphate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "threonine-phosphate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "D-methionine transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-methionine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of D-methionine from one side of a membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "beta tubulin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) "Interacting selectively and non-covalently with the microtubule constituent protein beta-tubulin."^^xsd:string) AnnotationAssertion(rdfs:label "beta-tubulin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Roundabout binding"^^xsd:string) AnnotationAssertion( "Roundabout receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) Annotation( "PMID:10102268"^^xsd:string) Annotation( "PMID:10197527"^^xsd:string) "Interacting selectively and non-covalently with the Roundabout (ROBO) receptor, a transmembrane receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "thiamine ABC transporter"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "thiamin-transporting ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiamine-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) Annotation( "PMID:9535878"^^xsd:string) "Catalysis of the reaction: ATP + H2O + thiamine(out) = ADP + phosphate + thiamine(in)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.81"^^xsd:string) "magnesium-protoporphyrin-IX 13-monomethyl ester,NADPH:oxygen oxidoreductase (hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.81"^^xsd:string) "Mg-protoporphyrin IX monomethyl ester oxidative cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.81"^^xsd:string) "Catalysis of the reaction: magnesium protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2 = divinylprotochlorophyllide + 3 NADP+ + 5 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.81"^^xsd:string) "Mg-protoporphyrin IX monomethyl ester (oxidative) cyclase activity"^^xsd:string) AnnotationAssertion(rdfs:label "magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11551958"^^xsd:string) "Catalysis of the transfer of a galactose residue from a donor molecule to an oligosaccharide, forming a beta-1,3-linkage."^^xsd:string) AnnotationAssertion(rdfs:label "beta-1,3-galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "metalloenzyme inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ebc"^^xsd:string) "Stops, prevents or reduces the activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcium-induced calcium release activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) Annotation( "GOC:nln"^^xsd:string) Annotation( "PMID:2990997"^^xsd:string) Annotation( "PMID:8381210"^^xsd:string) Annotation( "PMID:8653752"^^xsd:string) "Release of calcium ions from an intracellular vesicle on induction by increased calcium concentration."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.35"^^xsd:string) Annotation( "MetaCyc:D-GLUTAMINASE-RXN"^^xsd:string) "Catalysis of the reaction: H2O + L-glutamine = NH3 + D-glutamate."^^xsd:string) AnnotationAssertion(rdfs:label "D-glutaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.35"^^xsd:string) "D-glutamine amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.21.4.1"^^xsd:string) "5-aminopentanoate:lipoate oxidoreductase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.4.1"^^xsd:string) Annotation( "MetaCyc:D-PROLINE-REDUCTASE-(DITHIOL)-RXN"^^xsd:string) "Catalysis of the reaction: lipoate + 5-aminopentanoate = dihydrolipoate + D-proline."^^xsd:string) AnnotationAssertion(rdfs:label "D-proline reductase (dithiol) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.54"^^xsd:string) "deoxycytidylate methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.54"^^xsd:string) "5,10-methylenetetrahydrofolate:dCMP C-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "deoxycytidylate C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.54"^^xsd:string) Annotation( "RHEA:11571"^^xsd:string) "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP = 2'-deoxy-5-methyl-5'-cytidylate + 7,8-dihydrofolate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.54"^^xsd:string) "dCMP methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "isoflavone 7-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.170"^^xsd:string) Annotation( "MetaCyc:ISOFLAVONE-7-O-GLUCOSYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: UDP-glucose + isoflavone = UDP + isoflavone 7-O-beta-D-glucoside."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.170"^^xsd:string) "uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.170"^^xsd:string) "UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.170"^^xsd:string) "UDPglucose:isoflavone 7-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.170"^^xsd:string) "UDPglucose-flavonoid 7-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.170"^^xsd:string) "UDPglucose:isoflavone 7-O-beta-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.57"^^xsd:string) "3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase [3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA-forming]"^^xsd:string) AnnotationAssertion(rdfs:label "isohexenylglutaconyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.57"^^xsd:string) "3-hydroxy-3-isohexenylglutaryl-CoA-hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.57"^^xsd:string) "3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.57"^^xsd:string) Annotation( "RHEA:24147"^^xsd:string) "Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.57"^^xsd:string) "beta-isohexenylglutaconyl-CoA-hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.57"^^xsd:string) "isohexenylglutaconyl coenzyme A hydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.99.11"^^xsd:string) "sucrose glucosylmutase activity"^^xsd:string) AnnotationAssertion(rdfs:label "isomaltulose synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.11"^^xsd:string) Annotation( "MetaCyc:ISOMALTULOSE-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: sucrose = 6-O-alpha-D-glucopyranosyl-D-fructofuranose."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.11"^^xsd:string) "sucrose alpha-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.11"^^xsd:string) "trehalulose synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.11"^^xsd:string) "isomaltulose synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.38"^^xsd:string) Annotation( "RHEA:19848"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nocardicin E = S-methyl-5'-thioadenosine + H(+) + isonocardicin A."^^xsd:string) AnnotationAssertion(rdfs:label "isonocardicin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.38"^^xsd:string) "nocardicin aminocarboxypropyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.38"^^xsd:string) "S-adenosyl-L-methionine:nocardicin-E 3-amino-3-carboxypropyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.3.11"^^xsd:string) Annotation( "RHEA:21519"^^xsd:string) "Catalysis of the reaction: isopiperitenone = piperitenone."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.11"^^xsd:string) "isopiperitenone delta8-delta4-isomerase activity"^^xsd:string) AnnotationAssertion( "isopiperitenone D-isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "isopiperitenone delta-isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "isopropanol dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.80"^^xsd:string) Annotation( "RHEA:21795"^^xsd:string) "Catalysis of the reaction: NADP(+) + propan-2-ol = acetone + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.80"^^xsd:string) "propan-2-ol:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.106"^^xsd:string) "uridine diphosphoglucose-isovitexin 2''-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.106"^^xsd:string) "UDPglucose:isovitexin 2''-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "isovitexin b-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.106"^^xsd:string) Annotation( "RHEA:19532"^^xsd:string) "Catalysis of the reaction: isovitexin + UDP-D-glucose = H(+) + isovitexin 2''-O-beta-D-glucoside + UDP."^^xsd:string) AnnotationAssertion(rdfs:label "isovitexin beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.106"^^xsd:string) "UDP-glucose:isovitexin 2''-O-beta-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.56"^^xsd:string) "citramalyl-CoA hydro-lyase (itaconyl-CoA-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "itaconyl-CoA hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.56"^^xsd:string) "itaconyl coenzyme A hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.56"^^xsd:string) Annotation( "MetaCyc:ITACONYL-COA-HYDRATASE-RXN"^^xsd:string) "Catalysis of the reaction: citramalyl-CoA = itaconyl-CoA + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.56"^^xsd:string) "citramalyl-CoA hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.27"^^xsd:string) "naphthoquinone hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.27"^^xsd:string) "naphthoquinone-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.27"^^xsd:string) Annotation( "RHEA:18748"^^xsd:string) "Catalysis of the reaction: 5-hydroxy-1,4-naphthoquinone + AH(2) + O(2) = 3,5-dihydroxy-1,4-naphthoquinone + A + H(2)O + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.27"^^xsd:string) "5-hydroxy-1,4-naphthoquinone,hydrogen-donor:oxygen oxidoreductase (3-hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "juglone 3-monooxygenase activity"^^xsd:string) AnnotationAssertion( "juglone hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.12"^^xsd:string) "2-dehydropantoate formaldehyde-lyase (3-methyl-2-oxobutanoate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.12"^^xsd:string) "2-dehydropantoate formaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.12"^^xsd:string) Annotation( "MetaCyc:KETOPANTOALDOLASE-RXN"^^xsd:string) "Catalysis of the reaction: 2-dehydropantoate = 3-methyl-2-oxobutanoate + formaldehyde."^^xsd:string) AnnotationAssertion(rdfs:label "2-dehydropantoate aldolase activity"^^xsd:string) AnnotationAssertion( "ketopantoaldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.2"^^xsd:string) "phosphoketotetrose aldolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ketotetrose-phosphate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.2"^^xsd:string) Annotation( "RHEA:20935"^^xsd:string) "Catalysis of the reaction: L-erythrulose 1-phosphate = formaldehyde + glycerone phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.2"^^xsd:string) "erythrulose-1-phosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.2"^^xsd:string) "erythrulose-1-phosphate formaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.2"^^xsd:string) "erythrulose-1-phosphate formaldehyde-lyase (glycerone-phosphate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.2"^^xsd:string) "erythrose-1-phosphate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.95"^^xsd:string) "KHase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.95"^^xsd:string) Annotation( "RHEA:23607"^^xsd:string) "Catalysis of the reaction: kievitone hydrate = H(2)O + H(+) + kievitone."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.95"^^xsd:string) "kievitone-hydrate hydro-lyase (kievitone-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "kievitone hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.95"^^xsd:string) "kievitone-hydrate hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.2"^^xsd:string) "kynurenic acid hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.2"^^xsd:string) "kynurenic hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.2"^^xsd:string) Annotation( "MetaCyc:KYNURENINE-78-HYDROXYLASE-RXN"^^xsd:string) "Catalysis of the reaction: kynurenate + donor-H2 + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.2"^^xsd:string) "kynurenate 7,8-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.2"^^xsd:string) "kynurenate,hydrogen-donor:oxygen oxidoreductase (hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "kynurenine 7,8-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.9"^^xsd:string) "beta-cyano-L-alanine synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-3-cyanoalanine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.9"^^xsd:string) "beta-cyanoalanine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.9"^^xsd:string) "L-cysteine hydrogen-sulfide-lyase (adding hydrogen cyanide; L-3-cyanoalanine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.9"^^xsd:string) "beta-cyanoalanine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.9"^^xsd:string) Annotation( "MetaCyc:L-3-CYANOALANINE-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: L-cysteine + HCN = sulfide + L-3-cyanoalanine."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.9"^^xsd:string) "L-cysteine hydrogen-sulfide-lyase (adding HCN)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.1.5"^^xsd:string) Annotation( "MetaCyc:L-AMINO-ACID-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: an L-amino acid + H2O + NAD+ = a 2-oxo acid + NH3 + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "L-amino-acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.5"^^xsd:string) "L-amino-acid:NAD+ oxidoreductase (deaminating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.12"^^xsd:string) Annotation( "RHEA:16384"^^xsd:string) "Catalysis of the reaction: L-arabinitol + NAD(+) = L-xylulose + H(+) + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "L-arabinitol 4-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.25"^^xsd:string) "L-arabinonate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.25"^^xsd:string) "L-arabinonate hydro-lyase (2-dehydro-3-deoxy-L-arabinonate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.25"^^xsd:string) "L-arabonate dehydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-arabinonate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.25"^^xsd:string) Annotation( "RHEA:20971"^^xsd:string) "Catalysis of the reaction: L-arabinonate = 2-dehydro-3-deoxy-L-arabinonate + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.25"^^xsd:string) "L-arabonate dehydrase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.15"^^xsd:string) "L-arabinono-1,4-lactone lactonohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-arabinonolactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.15"^^xsd:string) Annotation( "RHEA:16220"^^xsd:string) "Catalysis of the reaction: L-arabinono-1,4-lactone + H(2)O = L-arabinonate + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-arabinose 1-dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.46"^^xsd:string) Annotation( "MetaCyc:L-ARABINOSE-1-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: L-arabinose + NAD+ = L-arabinono-1,4-lactone + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.46"^^xsd:string) "L-arabinose:NAD+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion( "L-arabinose 1-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-fuconate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.68"^^xsd:string) Annotation( "RHEA:22775"^^xsd:string) "Catalysis of the reaction: L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H(2)O."^^xsd:string) AnnotationAssertion( "L-fuconate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.68"^^xsd:string) "L-fuconate hydro-lyase (2-dehydro-3-deoxy-L-fuconate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.68"^^xsd:string) "L-fuconate hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.3.12"^^xsd:string) "L-xylono-1,4-lactone oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.12"^^xsd:string) "L-galactono-1,4-lactone oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.12"^^xsd:string) Annotation( "RHEA:20620"^^xsd:string) "Catalysis of the reaction: L-galactono-1,4-lactone + O(2) = L-ascorbate + H(2)O(2) + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.12"^^xsd:string) "L-galactono-1,4-lactone:oxygen 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-galactonolactone oxidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.3.11"^^xsd:string) "glutamate oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-glutamate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.11"^^xsd:string) "glutamic dehydrogenase (acceptor)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.11"^^xsd:string) "L-glutamate:oxygen oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.11"^^xsd:string) Annotation( "MetaCyc:L-GLUTAMATE-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: L-glutamate + O2 + H2O = 2-oxoglutarate + NH3 + H2O2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.11"^^xsd:string) "glutamate (acceptor) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.11"^^xsd:string) "glutamic acid oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.11"^^xsd:string) "L-glutamic acid oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.185"^^xsd:string) "glycol (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.185"^^xsd:string) Annotation( "MetaCyc:L-GLYCOL-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: an L-glycol + NAD(P)+ = a 2-hydroxycarbonyl compound + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.185"^^xsd:string) "L-glycol:NAD(P) dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-glycol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.185"^^xsd:string) "L-glycol:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.185"^^xsd:string) "L-(+)-glycol:NAD(P) oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.2.11"^^xsd:string) "L-alpha-aminocaprolactam hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.11"^^xsd:string) Annotation( "RHEA:21391"^^xsd:string) "Catalysis of the reaction: L-2-aminohexano-6-lactam + H(2)O = L-lysine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.11"^^xsd:string) "L-lysinamidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-lysine-lactamase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.11"^^xsd:string) "L-lysine-1,6-lactam lactamhydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-lysine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.14"^^xsd:string) Annotation( "RHEA:14440"^^xsd:string) "Catalysis of the reaction: L-lysine + H(2)O + O(2) = 6-amino-2-oxohexanoate + H(2)O(2) + NH(4)(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.14"^^xsd:string) "L-lysine alpha-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.14"^^xsd:string) "L-lysyl-alpha-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.14"^^xsd:string) "L-lysine:oxygen 2-oxidoreductase (deaminating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.99.3"^^xsd:string) "L-pipecolate:(acceptor) 1,6-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-pipecolate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.3"^^xsd:string) "L-pipecolate:acceptor 1,6-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.3"^^xsd:string) Annotation( "MetaCyc:L-PIPECOLATE-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: L-pipecolate + acceptor = delta1-piperideine-6-carboxylate + reduced acceptor. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.3.7"^^xsd:string) "L-pipecolate:oxygen 1,6-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.7"^^xsd:string) "L-pipecolic acid oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.7"^^xsd:string) Annotation( "RHEA:11995"^^xsd:string) "Catalysis of the reaction: L-pipecolate + O(2) = 2,3,4,5-tetrahydropyridine-2-carboxylate + H(2)O(2) + H(+). Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate."^^xsd:string) AnnotationAssertion(rdfs:label "L-pipecolate oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.90"^^xsd:string) "L-rhamnonate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.90"^^xsd:string) Annotation( "RHEA:23083"^^xsd:string) "Catalysis of the reaction: L-rhamnonate = 2-dehydro-3-deoxy-L-rhamnonate + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.90"^^xsd:string) "L-rhamnonate hydro-lyase (2-dehydro-3-deoxy-L-rhamnonate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "L-rhamnonate dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.65"^^xsd:string) "L-rhamno-gamma-lactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.65"^^xsd:string) Annotation( "RHEA:10291"^^xsd:string) "Catalysis of the reaction: L-rhamnono-1,4-lactone + H(2)O = L-rhamnonate + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "L-rhamnono-1,4-lactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.65"^^xsd:string) "L-rhamnono-gamma-lactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.65"^^xsd:string) "L-rhamnono-1,4-lactone lactonohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.173"^^xsd:string) "L-rhamnofuranose:NAD+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-rhamnose 1-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.173"^^xsd:string) Annotation( "RHEA:12652"^^xsd:string) "Catalysis of the reaction: L-rhamnofuranose + NAD(+) = L-rhamnono-1,4-lactone + H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.11"^^xsd:string) "L-sorbose:oxygen 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-sorbose oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.11"^^xsd:string) Annotation( "RHEA:17856"^^xsd:string) "Catalysis of the reaction: L-sorbose + O(2) = 5-dehydro-D-fructose + H(2)O(2)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.129"^^xsd:string) Annotation( "RHEA:23379"^^xsd:string) "Catalysis of the reaction: L-threonate + NAD(+) = 3-dehydro-L-threonate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.129"^^xsd:string) "L-threonic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-threonate 3-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.129"^^xsd:string) "L-threonate:NAD+ 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.129"^^xsd:string) "threonate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-xylose 1-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.113"^^xsd:string) "L-xylose:NADP+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.113"^^xsd:string) "L-xylose dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.113"^^xsd:string) "NADPH-xylose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.113"^^xsd:string) Annotation( "RHEA:15792"^^xsd:string) "Catalysis of the reaction: aldehydo-L-xylose + NADP(+) = L-xylono-1,4-lactone + H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-xylulose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.10"^^xsd:string) Annotation( "RHEA:17028"^^xsd:string) "Catalysis of the reaction: NADP(+) + xylitol = L-xylulose + H(+) + NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "L-xylulose reductase (NADP+) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.55"^^xsd:string) "propane-1,2-diol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.55"^^xsd:string) Annotation( "RHEA:15888"^^xsd:string) "Catalysis of the reaction: NADP(+) + propane-1,2-diol = (S)-lactaldehyde + H(+) + NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "lactaldehyde reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.55"^^xsd:string) "1,2-propanediol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.55"^^xsd:string) "propanediol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.55"^^xsd:string) "NADP-1,2-propanediol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.55"^^xsd:string) "lactaldehyde (reduced nicotinamide adenine dinucleotide phosphate) reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lactate 2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.4"^^xsd:string) "L-lactate-2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.4"^^xsd:string) "lactate oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.4"^^xsd:string) "lactate oxidative decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.4"^^xsd:string) "lactic oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.4"^^xsd:string) "L-lactate monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.4"^^xsd:string) "lactic oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.4"^^xsd:string) Annotation( "RHEA:16516"^^xsd:string) "Catalysis of the reaction: (S)-lactate + O(2) = acetate + CO(2) + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.4"^^xsd:string) "(S)-lactate:oxygen 2-oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.4"^^xsd:string) "lactate monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.4"^^xsd:string) "lactate oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lactate aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.36"^^xsd:string) "(S)-lactate acetaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.36"^^xsd:string) "lactate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.36"^^xsd:string) Annotation( "RHEA:17912"^^xsd:string) "Catalysis of the reaction: (S)-lactate = acetaldehyde + formate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.36"^^xsd:string) "(S)-lactate acetaldehyde-lyase (formate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.7"^^xsd:string) Annotation( "RHEA:10987"^^xsd:string) "Catalysis of the reaction: (S)-lactate + oxaloacetate = malate + pyruvate."^^xsd:string) AnnotationAssertion(rdfs:label "lactate-malate transhydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.7"^^xsd:string) "(S)-lactate:oxaloacetate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.7"^^xsd:string) "malate-lactate transhydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.2.1"^^xsd:string) "lactic acid racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.2.1"^^xsd:string) Annotation( "RHEA:10963"^^xsd:string) "Catalysis of the reaction: (S)-lactate = (R)-lactate."^^xsd:string) AnnotationAssertion(rdfs:label "lactate racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.2.1"^^xsd:string) "hydroxyacid racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.2.1"^^xsd:string) "lacticoracemase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.1.26"^^xsd:string) Annotation( "RHEA:13036"^^xsd:string) "Catalysis of the reaction: D-galactose 6-phosphate = D-tagatose 6-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.26"^^xsd:string) "D-galactose-6-phosphate ketol-isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactose-6-phosphate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.26"^^xsd:string) "D-galactose-6-phosphate aldose-ketose-isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.31"^^xsd:string) Annotation( "MetaCyc:LAMINARIBIOSE-PHOSPHORYLASE-RXN"^^xsd:string) "Catalysis of the reaction: 3-beta-D-glucosyl-D-glucose + phosphate = D-glucose + alpha-D-glucose 1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.31"^^xsd:string) "3-beta-D-glucosyl-D-glucose:phosphate alpha-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "laminaribiose phosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.21.6"^^xsd:string) "lathosterol 5-desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.21.6"^^xsd:string) "delta7-sterol-C5(6)-desaturase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lathosterol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.21.6"^^xsd:string) "5-DES"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.21.6"^^xsd:string) "5alpha-cholest-7-en-3beta-ol, NAD(P)H:oxygen 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.21.6"^^xsd:string) "delta7-sterol 5-desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.21.6"^^xsd:string) Annotation( "MetaCyc:LATHOSTEROL-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: 5-alpha-cholest-7-en-3-beta-ol + O2 = cholesta-5,7-dien-3-beta-ol + H2O2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.21.6"^^xsd:string) "delta7-sterol delta5-dehydrogenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.3.7"^^xsd:string) Annotation( "RHEA:10287"^^xsd:string) "Catalysis of the reaction: L-leucine = (3R)-beta-leucine."^^xsd:string) AnnotationAssertion(rdfs:label "leucine 2,3-aminomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.3.7"^^xsd:string) "(2S)-alpha-leucine 2,3-aminomutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.6"^^xsd:string) Annotation( "MetaCyc:LEUCINE-AMINOTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.6"^^xsd:string) "leucine 2-oxoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-leucine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.6"^^xsd:string) "leucine-alpha-ketoglutarate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.6"^^xsd:string) "L-leucine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.6"^^xsd:string) "leucine transaminase activity"^^xsd:string) AnnotationAssertion( "leucine aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.1.9"^^xsd:string) "L-leucine:NAD+ oxidoreductase, deaminating"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.9"^^xsd:string) "L-leucine:NAD+ oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.9"^^xsd:string) "L-leucine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.9"^^xsd:string) "LeuDH activity"^^xsd:string) AnnotationAssertion(rdfs:label "leucine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.9"^^xsd:string) Annotation( "MetaCyc:LEUCINE-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: L-leucine + H2O + NAD+ = 4-methyl-2-oxopentanoate + NH3 + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.66"^^xsd:string) "leucine acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.66"^^xsd:string) "acetyl-CoA:L-leucine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "leucine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.66"^^xsd:string) Annotation( "RHEA:20092"^^xsd:string) "Catalysis of the reaction: L-leucine + acetyl-CoA = N-acetyl-L-leucine + CoA + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.30"^^xsd:string) "leukotriene-B4 omega-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "leukotriene-B4 20-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.30"^^xsd:string) "LTB(4) 20-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.30"^^xsd:string) "leucotriene-B4 omega-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.30"^^xsd:string) "(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate,NADPH:oxygen oxidoreductase (20-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.30"^^xsd:string) "LTB4 omega-hydroxylase activity"^^xsd:string) AnnotationAssertion( "leukotriene-B4 20-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.30"^^xsd:string) "LTB(4) omega-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.30"^^xsd:string) "leukotriene-B(4) 20-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.30"^^xsd:string) "LTB4 20-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.30"^^xsd:string) Annotation( "MetaCyc:LEUKOTRIENE-B4-20-MONOOXYGENASE-RXN"^^xsd:string) "Catalysis of the reaction: (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + NADPH + H+ + O2 = (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + NADP+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.30"^^xsd:string) "leukotriene-B(4) omega-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "leukotriene-E4 w-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.34"^^xsd:string) Annotation( "RHEA:24123"^^xsd:string) "Catalysis of the reaction: H(+) + leukotriene E(4) + NADPH + O(2) = 20-hydroxy-leukotriene E(4) + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.34"^^xsd:string) "leukotriene-E4 omega-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "leukotriene-E4 20-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.34"^^xsd:string) "(7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate,NADPH:oxygen oxidoreductase (20-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.34"^^xsd:string) "leukotriene-E(4) omega-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.10"^^xsd:string) "beta-2,6-fructan:D-glucose 1-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.10"^^xsd:string) Annotation( "MetaCyc:LEVANSUCRASE-RXN"^^xsd:string) "Catalysis of the reaction: sucrose + 2,6-beta-D-fructosyl(n) = glucose + 2,6-beta-D-fructosyl(n+1)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.10"^^xsd:string) "beta-2,6-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.10"^^xsd:string) "sucrose 6-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.10"^^xsd:string) "sucrose:2,6-beta-D-fructan 6-beta-D-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "levansucrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.10"^^xsd:string) "sucrose 6-fructosyl transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "lignostilbene ab-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.43"^^xsd:string) "1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene:oxygen oxidoreductase (alphabeta-bond-cleaving)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.43"^^xsd:string) "lignostilbene alphabeta-dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lignostilbene alpha beta-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.43"^^xsd:string) Annotation( "RHEA:21343"^^xsd:string) "Catalysis of the reaction: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O(2) = 2 vanillin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.36"^^xsd:string) "limonin-D-ring-lactone hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.36"^^xsd:string) "limonin lactone hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "limonin-D-ring-lactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.36"^^xsd:string) "limonoate-D-ring-lactone lactonohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.36"^^xsd:string) Annotation( "MetaCyc:LIMONIN-D-RING-LACTONASE-RXN"^^xsd:string) "Catalysis of the reaction: limonoate D-ring-lactone + H2O = limonoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "linalool 8-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.28"^^xsd:string) Annotation( "RHEA:20763"^^xsd:string) "Catalysis of the reaction: AH(2) + linalool + O(2) = (2E)-2,6-dimethylocta-2,7-diene-1,6-diol + A + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.28"^^xsd:string) "3,7-dimethylocta-1,6-dien-3-ol,hydrogen-donor:oxygen oxidoreductase (8-hydroxylating)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.63"^^xsd:string) "uridine diphosphate-glucose-ketone cyanohydrin beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.63"^^xsd:string) "uridine diphosphoglucose-ketone glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.63"^^xsd:string) "UDP-glucose:2-hydroxy-2-methylpropanenitrile beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.63"^^xsd:string) "UDPglucose:2-hydroxy-2-methylpropanenitrile beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.63"^^xsd:string) Annotation( "MetaCyc:LINAMARIN-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: UDP-glucose + 2-hydroxy-2-methylpropanenitrile = UDP + linamarin."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.63"^^xsd:string) "UDPglucose:ketone cyanohydrin beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "linamarin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.63"^^xsd:string) "UDP glucose ketone cyanohydrin glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.63"^^xsd:string) "uridine diphosphoglucose-ketone cyanohydrin glucosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.2.1.5"^^xsd:string) Annotation( "RHEA:17384"^^xsd:string) "Catalysis of the reaction: linoleate = 9-cis,11-trans-octadecadienoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.5"^^xsd:string) "linoleate delta12-cis-delta11-trans-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.5"^^xsd:string) "linoleic acid isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "linoleate isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lombricine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.5"^^xsd:string) Annotation( "MetaCyc:LOMBRICINE-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + lombricine = ADP + N-phospholombricine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.5"^^xsd:string) "ATP:lombricine N-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.192"^^xsd:string) "long-chain-alcohol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "long-chain-alcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.192"^^xsd:string) "long-chain alcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.192"^^xsd:string) Annotation( "MetaCyc:LONG-CHAIN-ALCOHOL-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: a long-chain alcohol + 2 NAD+ + H2O = a long-chain carboxylate + 2 NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.192"^^xsd:string) "fatty alcohol oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.48"^^xsd:string) "long-chain aliphatic aldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.48"^^xsd:string) "fatty aldehyde:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.48"^^xsd:string) Annotation( "MetaCyc:LONG-CHAIN-ALDEHYDE-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+. A long-chain aldehyde is one with more than 12 carbons."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.48"^^xsd:string) "long-chain-aldehyde:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.48"^^xsd:string) "long-chain fatty aldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "long-chain-aldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "long-chain fatty acyl CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.50"^^xsd:string) Annotation( "MetaCyc:LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: a long-chain aldehyde + CoA + NADP+ = a long-chain acyl-CoA + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "long-chain fatty acyl-CoA reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "long-chain-fatty-acyl-CoA reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.50"^^xsd:string) "acyl coenzyme A reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.50"^^xsd:string) "long-chain-aldehyde:NADP+ oxidoreductase (acyl-CoA-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.29"^^xsd:string) "STK7"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.29"^^xsd:string) "low-density lipoprotein receptor kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.29"^^xsd:string) "ATP:low-density-lipoprotein-L-serine O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.29"^^xsd:string) "low-density-lipoprotein kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "low-density-lipoprotein particle receptor kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.29"^^xsd:string) "LDL receptor kinase activity"^^xsd:string) AnnotationAssertion( "[low-density lipoprotein receptor] kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.29"^^xsd:string) Annotation( "MetaCyc:LOW-DENSITY-LIPOPROTEIN-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + low-density lipoprotein L-serine = ADP + low-density lipoprotein O-phospho-L-serine."^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "low-density-lipoprotein receptor kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.29"^^xsd:string) "low-density-lipoprotein receptor kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.29"^^xsd:string) "ATP:low-density-lipoprotein receptor-L-serine O-phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.189"^^xsd:string) "LGT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.189"^^xsd:string) Annotation( "RHEA:10571"^^xsd:string) "Catalysis of the reaction: luteolin + UDP-alpha-D-glucuronate = luteolin 7-O-beta-D-glucosiduronate + UDP."^^xsd:string) AnnotationAssertion( "luteolin 7-O-glucoronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.189"^^xsd:string) "uridine diphosphoglucuronate-luteolin 7-O-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "luteolin 7-O-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.189"^^xsd:string) "UDPglucuronate:luteolin 7-O-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.189"^^xsd:string) "UDP-glucuronate:luteolin 7-O-glucuronosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.71"^^xsd:string) "Lys-AT"^^xsd:string) AnnotationAssertion( "lysine--pyruvate 6-aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lysine-pyruvate 6-transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.71"^^xsd:string) Annotation( "RHEA:19396"^^xsd:string) "Catalysis of the reaction: L-lysine + pyruvate = L-alanine + L-allysine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.71"^^xsd:string) "L-lysine:pyruvate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.71"^^xsd:string) "lysine-pyruvate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.3.2"^^xsd:string) "L-lysine 2,3-aminomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.3.2"^^xsd:string) Annotation( "RHEA:19180"^^xsd:string) "Catalysis of the reaction: L-lysine = (3S)-3,6-diaminohexanoate."^^xsd:string) AnnotationAssertion(rdfs:label "lysine 2,3-aminomutase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.12.2"^^xsd:string) "lysine oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.2"^^xsd:string) Annotation( "RHEA:14604"^^xsd:string) "Catalysis of the reaction: L-lysine + O(2) = 5-aminopentanamide + CO(2) + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.2"^^xsd:string) "L-lysine-2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.2"^^xsd:string) "lysine monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lysine 2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.2"^^xsd:string) "L-lysine:oxygen 2-oxidoreductase (decarboxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lysine carbamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.8"^^xsd:string) "lysine transcarbamylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.8"^^xsd:string) "carbamoyl-phosphate:L-lysine carbamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.8"^^xsd:string) Annotation( "RHEA:17124"^^xsd:string) "Catalysis of the reaction: L-lysine + carbamoyl phosphate = L-homocitrulline + H(+) + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.1.15"^^xsd:string) "L-lysine:NAD+ oxidoreductase (deaminating, cyclizing)"^^xsd:string) AnnotationAssertion(rdfs:label "lysine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.15"^^xsd:string) Annotation( "MetaCyc:LYSINE-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: L-lysine + NAD+ = 1,2-didehydropiperidine-2-carboxylate + NH3 + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.1.1"^^xsd:string) "lysolecithin 2,3-acylmutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.1.1"^^xsd:string) Annotation( "RHEA:24359"^^xsd:string) "Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine = 2-acyl-sn-glycero-3-phosphocholine."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.1.1"^^xsd:string) "lysolecithin migratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lysolecithin acylmutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.2.3"^^xsd:string) "L-lysyl-tRNA:phosphatidylglycerol 3-O-lysyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.3"^^xsd:string) "L-lysyl-tRNA:phosphatidylglycerol O3-lysyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lysyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.3"^^xsd:string) Annotation( "MetaCyc:LYSYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: L-lysyl-tRNA + phosphatidylglycerol = tRNA + 3-phosphatidyl-1'-(3'-O-L-lysyl)glycerol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "m7G(5')pppN diphosphatase activity"^^xsd:string) AnnotationAssertion( "M(7)G(5')pppN pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.30"^^xsd:string) "decapase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.30"^^xsd:string) "m7G(5')pppN pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.30"^^xsd:string) Annotation( "MetaCyc:M7G5PPPN-PYROPHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: 7-methylguanosine 5'-triphospho-5'-polynucleotide + H2O = 7-methylguanosine 5'-phosphate + polynucleotide."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.30"^^xsd:string) "7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.136"^^xsd:string) "ATP:macrolide 2'-O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "macrolide 2'-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.136"^^xsd:string) Annotation( "RHEA:18336"^^xsd:string) "Catalysis of the reaction: ATP + oleandomycin = ADP + 2 H(+) + oleandomycin 2'-O-phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.9"^^xsd:string) Annotation( "MetaCyc:MALATE--COA-LIGASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + malate + CoA = ADP + phosphate + malyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.9"^^xsd:string) "malyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.9"^^xsd:string) "malate thiokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.9"^^xsd:string) "malyl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.9"^^xsd:string) "malate:CoA ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "malate-CoA ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.31"^^xsd:string) "D-malate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.31"^^xsd:string) "malease activity"^^xsd:string) AnnotationAssertion(rdfs:label "maleate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.31"^^xsd:string) "(R)-malate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.31"^^xsd:string) Annotation( "RHEA:23695"^^xsd:string) "Catalysis of the reaction: (R)-malate = H(2)O + maleate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.31"^^xsd:string) "(R)-malate hydro-lyase (maleate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "maleate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.1"^^xsd:string) "maleate cis-trans-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.1"^^xsd:string) Annotation( "RHEA:13172"^^xsd:string) "Catalysis of the reaction: maleate = fumarate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.2.1.4"^^xsd:string) Annotation( "MetaCyc:MALEYLPYRUVATE-ISOMERASE-RXN"^^xsd:string) "Catalysis of the reaction: 3-maleylpyruvate = 3-fumarylpyruvate."^^xsd:string) AnnotationAssertion(rdfs:label "maleylpyruvate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.4"^^xsd:string) "3-maleylpyruvate cis-trans-isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.3.3"^^xsd:string) Annotation( "RHEA:18820"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + malonate = acetate + malonyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.3"^^xsd:string) "acetyl-CoA:malonate CoA-transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "malonate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.3"^^xsd:string) "malonate coenzyme A-transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "malonate-semialdehyde dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.27"^^xsd:string) "3-oxopropanoate hydro-lyase (propynoate-forming)"^^xsd:string) AnnotationAssertion( "acetylenecarboxylate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.27"^^xsd:string) "acetylmonocarboxylic acid hydrase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetylenecarboxylate hydratase activity, producing 3-oxopropanoate"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.27"^^xsd:string) "3-oxopropanoate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.27"^^xsd:string) Annotation( "MetaCyc:MALONATE-SEMIALDEHYDE-DEHYDRATASE-RXN"^^xsd:string) "Catalysis of the reaction: 3-oxopropanoate = propynoate + H2O."^^xsd:string) AnnotationAssertion( "alkynoate hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.27"^^xsd:string) "acetylenemonocarboxylate hydrase activity"^^xsd:string) AnnotationAssertion( "acetylenecarboxylate hydratase activity, producing malonate-semialdehyde"^^xsd:string) AnnotationAssertion( "acetylenemonocarboxylate hydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.9"^^xsd:string) "malonyl-CoA carboxy-lyase (acetyl-CoA-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.9"^^xsd:string) "malonyl-CoA carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.9"^^xsd:string) "malonyl coenzyme A decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.9"^^xsd:string) Annotation( "MetaCyc:MALONYL-COA-DECARBOXYLASE-RXN"^^xsd:string) "Catalysis of the reaction: malonyl-CoA = acetyl-CoA + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "malonyl-CoA decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.122"^^xsd:string) Annotation( "MetaCyc:MALTOSE-6-PHOSPHATE-GLUCOSIDASE-RXN"^^xsd:string) "Catalysis of the reaction: H2O + maltose 6'-phosphate = D-glucose + D-glucose 6-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.122"^^xsd:string) "maltose-6'-phosphate 6-phosphoglucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.122"^^xsd:string) "phospho-alpha-glucosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "maltose-6'-phosphate glucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "maltose phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.8"^^xsd:string) Annotation( "MetaCyc:MALTOSE-PHOSPHORYLASE-RXN"^^xsd:string) "Catalysis of the reaction: maltose + phosphate = D-glucose + beta-D-glucose 1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.8"^^xsd:string) "maltose:phosphate 1-beta-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3.24"^^xsd:string) "malyl-coenzyme A lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "malyl-CoA lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.24"^^xsd:string) "(3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.24"^^xsd:string) Annotation( "MetaCyc:MALYL-COA-LYASE-RXN"^^xsd:string) "Catalysis of the reaction: (3S)-3-carboxy-3-hydroxypropanoyl-CoA = acetyl-CoA + glyoxylate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.24"^^xsd:string) "(3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase (acetyl-CoA-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mannitol-1-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.22"^^xsd:string) "D-mannitol-1-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.22"^^xsd:string) Annotation( "RHEA:19540"^^xsd:string) "Catalysis of the reaction: D-mannitol 1-phosphate + H(2)O = D-mannitol + 2 H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.22"^^xsd:string) "mannitol-1-phosphate phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.138"^^xsd:string) "D-mannitol:NADP+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannitol 2-dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.138"^^xsd:string) Annotation( "RHEA:16768"^^xsd:string) "Catalysis of the reaction: D-mannitol + NADP(+) = D-fructose + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.138"^^xsd:string) "NADP-dependent mannitol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.67"^^xsd:string) Annotation( "MetaCyc:MANNITOL-2-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.67"^^xsd:string) "D-mannitol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.67"^^xsd:string) "D-mannitol:NAD+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannitol 2-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.2.2"^^xsd:string) Annotation( "MetaCyc:MANNITOL-DEHYDROGENASE-CYTOCHROME-RXN"^^xsd:string) "Catalysis of the reaction: D-mannitol + ferricytochrome c = D-fructose + ferrocytochrome c."^^xsd:string) AnnotationAssertion(rdfs:label "mannitol dehydrogenase (cytochrome) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.2"^^xsd:string) "polyol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.2"^^xsd:string) "D-mannitol:ferricytochrome-c 2-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.224"^^xsd:string) "NADPH-dependent M6P reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.224"^^xsd:string) "NADPH-mannose-6-P reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.224"^^xsd:string) "6-phosphomannose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.224"^^xsd:string) "mannose-6-phosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.224"^^xsd:string) "D-mannitol-1-phosphate:NADP+ 6-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.224"^^xsd:string) "NADPH-dependent mannose 6-phosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.224"^^xsd:string) "NADP-dependent mannose-6-P:mannitol-1-P oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannose-6-phosphate 6-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.224"^^xsd:string) Annotation( "RHEA:14928"^^xsd:string) "Catalysis of the reaction: D-mannitol 1-phosphate + NADP(+) = D-mannose 6-phosphate + 3 H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mannose isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.7"^^xsd:string) "D-mannose aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.7"^^xsd:string) "D-mannose ketol-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.7"^^xsd:string) Annotation( "RHEA:22607"^^xsd:string) "Catalysis of the reaction: D-mannose = D-fructose."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.7"^^xsd:string) "D-mannose isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.131"^^xsd:string) "D-mannonate:nicotinamide adenine dinucleotide (phosphate oxidoreductase (D-mannuronate-forming))"^^xsd:string) AnnotationAssertion(rdfs:label "mannuronate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.131"^^xsd:string) "D-mannonate:NAD(P)+ 6-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.131"^^xsd:string) "mannonate dehydrogenase (NAD(P)+)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.131"^^xsd:string) Annotation( "MetaCyc:MANNURONATE-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: D-mannonate + NAD(P)+ = D-mannuronate + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.131"^^xsd:string) "mannonate (nicotinamide adenine dinucleotide (phosphate))dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.131"^^xsd:string) "mannonate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.4"^^xsd:string) "melilotic hydroxylase activity"^^xsd:string) AnnotationAssertion( "melilotate hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "melilotate 3-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.4"^^xsd:string) "2-hydroxyphenylpropionic hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.4"^^xsd:string) "3-(2-hydroxyphenyl)propanoate,NADH:oxygen oxidoreductase (3-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.4"^^xsd:string) "2-hydroxyphenylpropionate hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.4"^^xsd:string) Annotation( "RHEA:17672"^^xsd:string) "Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + H(+) + NADH + O(2) = 3-(2,3-dihydroxyphenyl)propanoate + H(2)O + NAD(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.7"^^xsd:string) "meso-tartrate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "meso-tartrate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.7"^^xsd:string) Annotation( "RHEA:18556"^^xsd:string) "Catalysis of the reaction: (2R,3S)-tartrate + NAD(+) = dihydroxyfumarate + H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.244"^^xsd:string) Annotation( "RHEA:19404"^^xsd:string) "Catalysis of the reaction: methanol + NAD(+) = formaldehyde + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.244"^^xsd:string) "methanol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methanol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methionine-glyoxylate transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.73"^^xsd:string) "methionine-glyoxylate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.73"^^xsd:string) Annotation( "RHEA:22887"^^xsd:string) "Catalysis of the reaction: L-methionine + glyoxylate = 4-methylthio-2-oxobutanoate + glycine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.73"^^xsd:string) "L-methionine:glyoxylate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.73"^^xsd:string) "MGAT activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.57"^^xsd:string) "L-methionine carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.57"^^xsd:string) Annotation( "RHEA:17760"^^xsd:string) "Catalysis of the reaction: L-methionine + H(+) = 3-methylthiopropanamine + CO(2)."^^xsd:string) AnnotationAssertion(rdfs:label "methionine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.57"^^xsd:string) "L-methionine carboxy-lyase (3-methylthiopropanamine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.57"^^xsd:string) "L-methionine decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methylaspartate ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.2"^^xsd:string) "L-threo-3-methylaspartate ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.2"^^xsd:string) "beta-methylaspartase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.2"^^xsd:string) Annotation( "RHEA:12832"^^xsd:string) "Catalysis of the reaction: threo-3-methyl-L-aspartate = mesaconate + NH(4)(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.2"^^xsd:string) "3-methylaspartase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.2"^^xsd:string) "L-threo-3-methylaspartate ammonia-lyase (mesaconate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.99.1"^^xsd:string) "glutamate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.1"^^xsd:string) "glutamic acid mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.1"^^xsd:string) "methylaspartic acid mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.1"^^xsd:string) "glutamic acid isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.1"^^xsd:string) "b-methylaspartate-glutamate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.1"^^xsd:string) "L-threo-3-methylaspartate carboxy-aminomethylmutase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methylaspartate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.1"^^xsd:string) "glutamic isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.1"^^xsd:string) "beta-methylaspartate-glutamate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.1"^^xsd:string) "glutamic mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.1"^^xsd:string) "glutamate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.1"^^xsd:string) Annotation( "RHEA:12860"^^xsd:string) "Catalysis of the reaction: threo-3-methyl-L-aspartate = L-glutamate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.16"^^xsd:string) "methylguanidine amidinohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.16"^^xsd:string) Annotation( "RHEA:11767"^^xsd:string) "Catalysis of the reaction: H(2)O + methylguanidine = methylammonium + urea."^^xsd:string) AnnotationAssertion(rdfs:label "methylguanidinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.16"^^xsd:string) "methylguanidine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.99.5"^^xsd:string) "N-methyl-L-glutamate:(acceptor) oxidoreductase (demethylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.5"^^xsd:string) "N-methyl-L-glutamate:acceptor oxidoreductase (demethylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.5"^^xsd:string) "N-methylglutamate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.5"^^xsd:string) Annotation( "RHEA:22575"^^xsd:string) "Catalysis of the reaction: N-methyl-L-glutamate + A + H(2)O = L-glutamate + AH(2) + formaldehyde."^^xsd:string) AnnotationAssertion(rdfs:label "methylglutamate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.3.6"^^xsd:string) "methylitaconate isomerase activity"^^xsd:string) AnnotationAssertion( "methylitaconate D-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.6"^^xsd:string) Annotation( "RHEA:23483"^^xsd:string) "Catalysis of the reaction: 2-methylene-3-methylsuccinate = dimethylmaleate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.6"^^xsd:string) "methylitaconate delta2-delta3-isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methylitaconate delta-isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.61"^^xsd:string) Annotation( "RHEA:13376"^^xsd:string) "Catalysis of the reaction: L-mimosine + H(2)O = 3-hydroxy-4H-pyrid-4-one + L-serine."^^xsd:string) AnnotationAssertion(rdfs:label "mimosinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.61"^^xsd:string) "mimosine amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cellodextrin phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.49"^^xsd:string) Annotation( "MetaCyc:CELLODEXTRIN-PHOSPHORYLASE-RXN"^^xsd:string) "Catalysis of the reaction: 1,4-beta-D-glucosyl(n) + phosphate = 1,4-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.49"^^xsd:string) "beta-1,4-oligoglucan:orthophosphate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.49"^^xsd:string) "1,4-beta-D-oligo-D-glucan:phosphate alpha-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.2"^^xsd:string) "dextrin 6-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dextrin dextranase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.2"^^xsd:string) Annotation( "MetaCyc:DEXTRIN-DEXTRANASE-RXN"^^xsd:string) "Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + 1,6-alpha-D-glucosyl(m) = 1,4-alpha-D-glucosyl(n-1) + 1,6-alpha-D-glucosyl(m+1)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.2"^^xsd:string) "dextran dextrinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.2"^^xsd:string) "1,4-alpha-D-glucan:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.45"^^xsd:string) "L-3-hydroxyacid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.45"^^xsd:string) Annotation( "RHEA:12892"^^xsd:string) "Catalysis of the reaction: L-gulonate + NAD(+) = 3-dehydro-L-gulonate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.45"^^xsd:string) "L-3-aldonate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.45"^^xsd:string) "L-gulonic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-gulonate 3-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.45"^^xsd:string) "L-beta-hydroxyacid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.45"^^xsd:string) "L-3-aldonic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.45"^^xsd:string) "L-beta-hydroxy-acid-NAD-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.45"^^xsd:string) "L-gulonate:NAD+ 3-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.8"^^xsd:string) "L-gulono-gamma-lactone oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-gulonolactone oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.8"^^xsd:string) "L-gulono-gamma-lactone:oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.8"^^xsd:string) "L-gulono-1,4-lactone:oxygen 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.8"^^xsd:string) "L-gulono-gamma-lactone:O2 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.8"^^xsd:string) "GLO activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.8"^^xsd:string) Annotation( "MetaCyc:L-GULONOLACTONE-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: L-gulono-1,4-lactone + O2 = L-xylo-hex-3-ulonolactone + H2O2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "monomethyl-sulphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.16"^^xsd:string) Annotation( "RHEA:14224"^^xsd:string) "Catalysis of the reaction: H(2)O + monomethyl sulfate = H(+) + methanol + sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.6.16"^^xsd:string) "monomethyl-sulfate sulfohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "monomethyl-sulfatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.69"^^xsd:string) "acetyl-CoA:monoterpenol O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.69"^^xsd:string) "menthol transacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.69"^^xsd:string) Annotation( "MetaCyc:MONOTERPENOL-O-ACETYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + a monoterpenol = CoA + a monoterpenol acetate ester."^^xsd:string) AnnotationAssertion(rdfs:label "monoterpenol O-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "monoterpenyl-diphosphatase activity"^^xsd:string) AnnotationAssertion( "monoterpenyl-pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.7.3"^^xsd:string) Annotation( "MetaCyc:MONOTERPENYL-PYROPHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: monoterpenyl diphosphate + H2O = monoterpenol + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.7.3"^^xsd:string) "bornyl pyrophosphate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.7.3"^^xsd:string) "bornyl diphosphate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.7.3"^^xsd:string) "monoterpenyl-diphosphate diphosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.218"^^xsd:string) "morphine:NAD(P)+ 6-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.218"^^xsd:string) "reductase, naloxone"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.218"^^xsd:string) Annotation( "MetaCyc:MORPHINE-6-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: morphine + NAD(P)+ = morphinone + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(rdfs:label "morphine 6-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.218"^^xsd:string) "naloxone reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.110"^^xsd:string) "endo-beta-N-acetyl-D-galactosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.110"^^xsd:string) "D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine mucinaminohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mucinaminylserine mucinaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:3.2.1.110-RXN"^^xsd:string) "Catalysis of the reaction: D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-serine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.110"^^xsd:string) "endo-beta-N-acetylgalactosaminidase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.111"^^xsd:string) "mycocerosic acid synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mycocerosate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.111"^^xsd:string) Annotation( "RHEA:10591"^^xsd:string) "Catalysis of the reaction: acyl-CoA + 7n H(+) + n methylmalonyl-CoA + 2n NADPH = n CO(2) + n CoA + n H(2)O + multi-methyl-branched acyl-CoA + 2n NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.111"^^xsd:string) "acyl-CoA:methylmalonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "inositol:NAD 2-dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol 2-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.18"^^xsd:string) Annotation( "RHEA:16952"^^xsd:string) "Catalysis of the reaction: myo-inositol + NAD(+) = 2,4,6/3,5-pentahydroxycyclohexanone + H(+) + NADH."^^xsd:string) AnnotationAssertion( "myo-inositol 2-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.99.1"^^xsd:string) "MOO activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.99.1"^^xsd:string) Annotation( "RHEA:23699"^^xsd:string) "Catalysis of the reaction: myo-inositol + O(2) = D-glucuronate + H(2)O + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.99.1"^^xsd:string) "meso-inositol oxygenase activity"^^xsd:string) AnnotationAssertion( "myo-inositol oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.99.1"^^xsd:string) "myo-inositol:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "myo-inosose-2 dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.44"^^xsd:string) "ketoinositol dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.44"^^xsd:string) Annotation( "RHEA:14068"^^xsd:string) "Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone = 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.44"^^xsd:string) "2,4,6/3,5-pentahydroxycyclohexanone hydro-lyase (3,5/4-trihydroxycyclohexa-1,2-dione-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.44"^^xsd:string) "inosose 2,3-dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.44"^^xsd:string) "2,4,6/3,5-pentahydroxycyclohexanone hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.53"^^xsd:string) "myosin light chain kinase phosphatase activity"^^xsd:string) AnnotationAssertion( "[Myosin light-chain]-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.53"^^xsd:string) "myosin-light-chain phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.53"^^xsd:string) Annotation( "MetaCyc:MYOSIN-LIGHT-CHAIN-PHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: myosin light-chain phosphate + H2O = myosin light chain + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.53"^^xsd:string) "protein phosphatase 2A"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.53"^^xsd:string) "myosin light-chain kinase phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "myosin-light-chain-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.53"^^xsd:string) "myosin-light-chain-phosphate phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N,N-dimethylformamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.56"^^xsd:string) Annotation( "RHEA:19520"^^xsd:string) "Catalysis of the reaction: N,N-dimethylformamide + H(2)O = dimethylamine + formate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.56"^^xsd:string) "dimethylformamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.56"^^xsd:string) "DMFase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.56"^^xsd:string) "N,N-dimethylformamide amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.21"^^xsd:string) "N-acetyl-beta-alanine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.21"^^xsd:string) Annotation( "RHEA:23215"^^xsd:string) "Catalysis of the reaction: N-acetyl-beta-alanine + H(2)O = beta-alanine + acetate."^^xsd:string) AnnotationAssertion(rdfs:label "N-acetyl-beta-alanine deacetylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.47"^^xsd:string) "N6-acetyl-LL-2,6-diaminoheptanedioate amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.47"^^xsd:string) Annotation( "RHEA:20408"^^xsd:string) "Catalysis of the reaction: N-acetyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + acetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.47"^^xsd:string) "N-acetyl-L-diaminopimelic acid deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.47"^^xsd:string) "6-N-acetyl-LL-2,6-diaminoheptanedioate amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetyldiaminopimelate deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.47"^^xsd:string) "N-acetyl-LL-diaminopimelate deacylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.33"^^xsd:string) "acetylaminodeoxyglucose acetylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.33"^^xsd:string) "N-acetyl-D-glucosaminyl N-deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.33"^^xsd:string) "N-acetyl-D-glucosamine amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylglucosamine deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.33"^^xsd:string) Annotation( "RHEA:20596"^^xsd:string) "Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O = D-glucosamine + acetate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.240"^^xsd:string) "N-acetylhexosamine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.240"^^xsd:string) "N-acetyl-D-hexosamine dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylhexosamine 1-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.240"^^xsd:string) Annotation( "RHEA:23147"^^xsd:string) "Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O + NAD(+) = N-acetyl-D-glucosaminate + 2 H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.240"^^xsd:string) "N-acetyl-D-hexosamine:NAD+ 1-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.8"^^xsd:string) "GlcNAc 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.8"^^xsd:string) "N-acyl-D-glucosamine 2-epimerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acylglucosamine 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.8"^^xsd:string) Annotation( "MetaCyc:N-ACYLGLUCOSAMINE-2-EPIMERASE-RXN"^^xsd:string) "Catalysis of the reaction: N-acyl-D-glucosamine = N-acyl-D-mannosamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.8"^^xsd:string) "N-acetyl-D-glucosamine 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.8"^^xsd:string) "acylglucosamine 2-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.8"^^xsd:string) "N-acetylglucosamine 2-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.29"^^xsd:string) "N-acyl-D-hexosamine:oxygen 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acylhexosamine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.29"^^xsd:string) Annotation( "RHEA:13032"^^xsd:string) "Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O + O(2) = N-acetyl-D-glucosaminate + H(2)O(2) + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.29"^^xsd:string) "N-acyl-beta-D-hexosamine:oxygen 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.29"^^xsd:string) "N-acyl-D-hexosamine oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.233"^^xsd:string) "N-acyl-D-mannosamine:NAD+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.233"^^xsd:string) "N-acylmannosamine dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acylmannosamine 1-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.233"^^xsd:string) "N-acyl-D-mannosamine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.233"^^xsd:string) Annotation( "RHEA:11543"^^xsd:string) "Catalysis of the reaction: N-acyl-D-mannosamine + NAD(+) = N-acyl-D-mannosaminolactone + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.233"^^xsd:string) "N-acetyl-D-mannosamine dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-acylneuraminate-9-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.29"^^xsd:string) "N-acylneuraminic acid 9-phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.29"^^xsd:string) Annotation( "MetaCyc:N-ACYLNEURAMINATE-9-PHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: N-acylneuraminate 9-phosphate + H2O = N-acylneuraminate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.29"^^xsd:string) "N-acylneuraminate-9-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.29"^^xsd:string) "acylneuraminate 9-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.29"^^xsd:string) "N-acylneuraminic (sialic) acid 9-phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.58"^^xsd:string) Annotation( "RHEA:20903"^^xsd:string) "Catalysis of the reaction: N-benzyloxycarbonylglycine + H(2)O + H(+) = benzyl alcohol + CO(2) + glycine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.58"^^xsd:string) "nalpha-carbobenzoxyamino acid amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.58"^^xsd:string) "nalpha-benzyloxycarbonyl amino acid urethane hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.58"^^xsd:string) "benzyloxycarbonylglycine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.58"^^xsd:string) "nalpha-benzyloxycarbonyl amino acid urethane hydrolase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.58"^^xsd:string) "N-benzyloxycarbonylglycine urethanehydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-benzyloxycarbonylglycine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.53"^^xsd:string) "N-carbamoylputrescine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.53"^^xsd:string) "carbamoylputrescine hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-carbamoylputrescine amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.53"^^xsd:string) Annotation( "RHEA:22287"^^xsd:string) "Catalysis of the reaction: N-carbamoylputrescine + H(2)O + 2 H(+) = CO(2) + NH(4)(+) + putrescine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.53"^^xsd:string) "NCP"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.59"^^xsd:string) "carbamoylsarcosine amidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-carbamoylsarcosine amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.59"^^xsd:string) Annotation( "RHEA:20060"^^xsd:string) "Catalysis of the reaction: N-carbamoylsarcosine + H(2)O + 2 H(+) = CO(2) + NH(4)(+) + sarcosine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.59"^^xsd:string) "N-carbamoylsarcosine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.59"^^xsd:string) "CSHase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-feruloylglycine deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.71"^^xsd:string) "N-feruloylglycine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.71"^^xsd:string) Annotation( "RHEA:10487"^^xsd:string) "Catalysis of the reaction: N-feruloylglycine + H(2)O = ferulate + glycine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.71"^^xsd:string) "N-feruloylglycine amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.68"^^xsd:string) "beta-citryl-L-glutamate-hydrolyzing enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.68"^^xsd:string) "beta-citrylglutamate amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.68"^^xsd:string) "N-formyl-L-glutamate amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.68"^^xsd:string) Annotation( "RHEA:12479"^^xsd:string) "Catalysis of the reaction: N-formyl-L-glutamate + H(2)O = L-glutamate + formate."^^xsd:string) AnnotationAssertion(rdfs:label "N-formylglutamate deformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.68"^^xsd:string) "beta-citryl-L-glutamate amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.68"^^xsd:string) "formylglutamate deformylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.68"^^xsd:string) "beta-citryl-L-glutamate amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.68"^^xsd:string) "N-formylglutamate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.68"^^xsd:string) "beta-citryl-L-glutamate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.36"^^xsd:string) "N-methyl-2-oxoglutaramate methylamidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.36"^^xsd:string) "5-hydroxy-N-methylpyroglutamate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-methyl-2-oxoglutaramate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.36"^^xsd:string) Annotation( "RHEA:24111"^^xsd:string) "Catalysis of the reaction: N-methyl-2-oxoglutaramate + H(2)O = 2-oxoglutarate + methylammonium."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.3.2"^^xsd:string) Annotation( "MetaCyc:N-METHYL-L-AMINO-ACID-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: an N-methyl-L-amino acid + H2O + O2 = an L-amino acid + formaldehyde + H2O2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.2"^^xsd:string) "N-methyl-L-amino-acid:oxygen oxidoreductase (demethylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.2"^^xsd:string) "N-methylamino acid oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-methyl-L-amino-acid oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.1.17"^^xsd:string) Annotation( "RHEA:21771"^^xsd:string) "Catalysis of the reaction: N-methyl-L-alanine + H(2)O + NADP(+) = H(+) + methylammonium + NADPH + pyruvate."^^xsd:string) AnnotationAssertion(rdfs:label "N-methylalanine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.17"^^xsd:string) "N-methyl-L-alanine:NADP+ oxidoreductase (demethylating, deaminating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.102"^^xsd:string) Annotation( "RHEA:22391"^^xsd:string) "Catalysis of the reaction: N(6)-hydroxy-L-lysine + acetyl-CoA = N(6)-acetyl-N(6)-hydroxy-L-lysine + CoA."^^xsd:string) AnnotationAssertion(rdfs:label "N6-hydroxylysine O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.102"^^xsd:string) "N(6)-hydroxylysine acetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.102"^^xsd:string) "acetyl-CoA:N6-hydroxy-L-lysine 6-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.102"^^xsd:string) "N6-hydroxylysine:acetyl CoA N6-transacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.102"^^xsd:string) "N6-hydroxylysine acetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.102"^^xsd:string) "acetyl-CoA:6-N-hydroxy-L-lysine 6-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.3.4"^^xsd:string) "N6-methyl-L-lysine:oxygen oxidoreductase (demethylating)"^^xsd:string) AnnotationAssertion(rdfs:label "N6-methyl-lysine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.4"^^xsd:string) "epsilon-alkyl-L-lysine:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.4"^^xsd:string) "epsilon-N-methyllysine demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.4"^^xsd:string) "N6-methyllysine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.4"^^xsd:string) "epsilon-alkyllysinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.4"^^xsd:string) "N(6)-methyllysine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.4"^^xsd:string) "6-N-methyl-L-lysine:oxygen oxidoreductase (demethylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.4"^^xsd:string) Annotation( "RHEA:23203"^^xsd:string) "Catalysis of the reaction: N(6)-methyl-L-lysine + H(2)O + O(2) = L-lysine + formaldehyde + H(2)O(2)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.6"^^xsd:string) "triphosphopyridine nucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.6"^^xsd:string) "NAD(P)+ glycohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.6"^^xsd:string) "nicotinamide adenine dinucleotide (phosphate) glycohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "NAD(P)+ nucleosidase activity"^^xsd:string) AnnotationAssertion( "NAD(P)(+) nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.6"^^xsd:string) "nicotinamide adenine dinucleotide (phosphate) nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.6"^^xsd:string) Annotation( "MetaCyc:NADP+-NUCLEOSIDASE-RXN"^^xsd:string) "Catalysis of the reaction: NAD(P)+ + H2O = ADP-ribose(P) + nicotinamide."^^xsd:string) AnnotationAssertion( "NAD(P) nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.6"^^xsd:string) "NAD(P)ase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.6.99.5"^^xsd:string) "D-diaphorase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.5"^^xsd:string) "reduced nicotinamide adenine dinucleotide (quinone) dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.5"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "MetaCyc:NADH-DEHYDROGENASE-QUINONE-RXN"^^xsd:string) "Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol."^^xsd:string) AnnotationAssertion(rdfs:label "NADH dehydrogenase (quinone) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.5"^^xsd:string) "NADH-quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.5"^^xsd:string) "DPNH-menadione reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.99.5"^^xsd:string) "NADH:(quinone-acceptor) oxidoreductase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.11.1.2"^^xsd:string) "TPN peroxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "NADPH peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.2"^^xsd:string) "NADPH:hydrogen-peroxide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.2"^^xsd:string) "NADP peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.2"^^xsd:string) "nicotinamide adenine dinucleotide phosphate peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.2"^^xsd:string) "TPNH peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.2"^^xsd:string) Annotation( "RHEA:15176"^^xsd:string) "Catalysis of the reaction: H(2)O(2) + H(+) + NADPH = 2 H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.2"^^xsd:string) "triphosphopyridine nucleotide peroxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.17.1.5"^^xsd:string) "nicotinate hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nicotinate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.5"^^xsd:string) "nicotinate:NADP+ 6-oxidoreductase (hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.5"^^xsd:string) Annotation( "RHEA:12239"^^xsd:string) "Catalysis of the reaction: H(2)O + NADP(+) + nicotinate = 6-hydroxynicotinate + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.5"^^xsd:string) "nicotinic acid hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.196"^^xsd:string) Annotation( "RHEA:19440"^^xsd:string) "Catalysis of the reaction: nicotinate + UDP-D-glucose = N-(beta-D-glucosyl)nicotinate + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.196"^^xsd:string) "uridine diphosphoglucose-nicotinate N-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nicotinate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.196"^^xsd:string) "UDP-glucose:nicotinate N-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.196"^^xsd:string) "UDPglucose:nicotinate N-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.196"^^xsd:string) "UDP-glucose:nicotinic acid-N-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.9.6.1"^^xsd:string) Annotation( "MetaCyc:NITRATE-REDUCTASE-CYTOCHROME-RXN"^^xsd:string) "Catalysis of the reaction: ferrocytochrome + nitrate = ferricytochrome + nitrite."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.6.1"^^xsd:string) "benzyl viologen-nitrate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.9.6.1"^^xsd:string) "ferrocytochrome:nitrate oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nitrate reductase (cytochrome) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.3.1"^^xsd:string) "nitroethane reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.3.1"^^xsd:string) Annotation( "MetaCyc:NITROETHANE-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: nitroethane + H2O + O2 = acetaldehyde + nitrite + H2O2."^^xsd:string) AnnotationAssertion(rdfs:label "nitroethane oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.3.1"^^xsd:string) "nitroethane:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.19.6.1"^^xsd:string) "reduced flavodoxin:dinitrogen oxidoreductase (ATP-hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.19.6.1"^^xsd:string) Annotation( "MetaCyc:NITROGENASE-FLAVODOXIN-RXN"^^xsd:string) "Catalysis of the reaction: 6 reduced flavodoxin + 6 H+ + N2 + n ATP = 6 oxidized flavodoxin + 2 NH3 + n ADP + n phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "nitrogenase (flavodoxin) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.1.14"^^xsd:string) "isonocardicin A epimerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nocardicin-A epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.14"^^xsd:string) Annotation( "RHEA:22795"^^xsd:string) "Catalysis of the reaction: isonocardicin A = nocardicin A."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.6"^^xsd:string) Annotation( "MetaCyc:NUCLEOSIDE-DEOXYRIBOSYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: 2-deoxy-D-ribosyl-base1 + base2 = 2-deoxy-D-ribosyl-base2 + base1."^^xsd:string) AnnotationAssertion(rdfs:label "nucleoside deoxyribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.6"^^xsd:string) "trans-N-glycosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.6"^^xsd:string) "trans-deoxyribosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.6"^^xsd:string) "deoxyribose transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.6"^^xsd:string) "nucleoside:purine(pyrimidine) deoxy-D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.6"^^xsd:string) "nucleoside trans-N-deoxyribosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.6"^^xsd:string) "purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.6"^^xsd:string) "trans-N-deoxyribosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.6"^^xsd:string) "nucleoside deoxyribosyltransferase I (purine nucleoside:purine deoxyribosyltransferase: strictly specific for transfer between purine bases)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.6"^^xsd:string) "nucleoside deoxyribosyltransferase II [purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyltransferase]"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nucleoside phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.4"^^xsd:string) "NMP-kinase activity"^^xsd:string) AnnotationAssertion( "nucleoside-phosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.4"^^xsd:string) "ATP:nucleoside-phosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "nucleoside monophosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.4"^^xsd:string) Annotation( "MetaCyc:NUCLEOSIDE-PHOSPHATE-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + nucleoside phosphate = ADP + nucleoside diphosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.77"^^xsd:string) Annotation( "MetaCyc:NUCLEOSIDE-PHOSPHOTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: a nucleotide + a 2'-deoxynucleoside = a nucleoside + a 2'-deoxynucleoside 5'-monophosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.77"^^xsd:string) "nucleotide:3'-deoxynucleoside 5'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nucleoside phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.77"^^xsd:string) "nonspecific nucleoside phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.77"^^xsd:string) "nucleotide:2'-nucleoside 5'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.77"^^xsd:string) "nucleotide:nucleoside 5'-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.5"^^xsd:string) Annotation( "MetaCyc:NUCLEOSIDE-RIBOSYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: D-ribosyl-base1 + base2 = D-ribosyl-base2 + base1."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.5"^^xsd:string) "nucleoside:purine(pyrimidine) D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nucleoside ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.5"^^xsd:string) "nucleoside N-ribosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.6.4"^^xsd:string) "ATP:nucleotide pyrophosphotransferase activity"^^xsd:string) AnnotationAssertion( "nucleotide pyrophosphokinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nucleotide diphosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.4"^^xsd:string) "ATP nucleotide 3'-pyrophosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.4"^^xsd:string) "nucleotide 3'-pyrophosphokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.4"^^xsd:string) "ATP:nucleoside-5'-phosphate diphosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.6.4"^^xsd:string) Annotation( "MetaCyc:NUCLEOTIDE-PYROPHOSPHOKINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + nucleoside 5'-phosphate = AMP + 5'-phosphonucleoside 3'-diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.10.3.4"^^xsd:string) "o-aminophenol:O2 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.4"^^xsd:string) Annotation( "MetaCyc:O-AMINOPHENOL-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: 2 2-aminophenol + 3 O2 = 2 isophenoxazine + 6 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.4"^^xsd:string) "2-aminophenol:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.4"^^xsd:string) "2-aminophenol:O2 oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "o-aminophenol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.4"^^xsd:string) "GriF"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.4"^^xsd:string) "isophenoxazine synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2,3-dihydroxybenzoate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.46"^^xsd:string) "2,3-dihydroxybenzoate carboxy-lyase (catechol-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.46"^^xsd:string) Annotation( "RHEA:21495"^^xsd:string) "Catalysis of the reaction: 2,3-dihydroxybenzoate + H(+) = catechol + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.46"^^xsd:string) "2,3-dihydroxybenzoic acid decarboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "o-pyrocatechuate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.46"^^xsd:string) "2,3-dihydroxybenzoate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.46"^^xsd:string) "2,3-DHBA decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.53"^^xsd:string) Annotation( "RHEA:21855"^^xsd:string) "Catalysis of the reaction: (R)-10-hydroxystearate = H(2)O + oleate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.53"^^xsd:string) "(R)-10-hydroxystearate 10-hydro-lyase (oleate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.53"^^xsd:string) "(R)-10-hydroxystearate 10-hydro-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oleate hydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "w-amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.3"^^xsd:string) Annotation( "MetaCyc:OMEGA-AMIDASE-RXN"^^xsd:string) "Catalysis of the reaction: a monoamide of a dicarboxylic acid + H2O = a dicarboxylate + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.3"^^xsd:string) "omega-amidodicarboxylate amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.3"^^xsd:string) "alpha-keto acid-omega-amidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "omega-amidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "w-hydroxydecanoate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.66"^^xsd:string) "10-hydroxydecanoate:NAD+ 10-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "omega-hydroxydecanoate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.66"^^xsd:string) Annotation( "RHEA:20883"^^xsd:string) "Catalysis of the reaction: 10-hydroxydecanoate + NAD(+) = 10-oxodecanoate + H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "opheline kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.7"^^xsd:string) Annotation( "RHEA:17556"^^xsd:string) "Catalysis of the reaction: ATP + guanidinoethyl methyl phosphate = N'-phosphoguanidinoethyl methylphosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.7"^^xsd:string) "ATP:guanidinoethyl-methyl-phosphate phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.68"^^xsd:string) "lysine/ornithine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.68"^^xsd:string) "L-ornithine:2-oxoglutarate-aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.68"^^xsd:string) Annotation( "MetaCyc:ORNITHINELYSINE-AMINOTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + L-ornithine = H2O + L-glutamate + 3,4-dihydro-2H-pyrrole-2-carboxylate."^^xsd:string) AnnotationAssertion( "ornithine(lysine) aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ornithine(lysine) transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.68"^^xsd:string) "L-ornithine(L-lysine):2-oxoglutarate-aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.127"^^xsd:string) "ornithine N-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.127"^^xsd:string) "benzoyl-CoA:L-ornithine N-benzoyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ornithine N-benzoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.127"^^xsd:string) Annotation( "RHEA:16932"^^xsd:string) "Catalysis of the reaction: L-ornithine + 2 benzoyl-CoA = N(2),N(5)-dibenzoyl-L-ornithine + 2 CoA + 2 H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ornithine racemase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.1.12"^^xsd:string) Annotation( "MetaCyc:ORNITHINE-RACEMASE-RXN"^^xsd:string) "Catalysis of the reaction: L-ornithine = D-ornithine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.15"^^xsd:string) "L-5,6-dihydro-orotate:NAD oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.15"^^xsd:string) "orotate reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "orotate reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.15"^^xsd:string) "(S)-dihydroorotate:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.15"^^xsd:string) "dihydro-orotic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.15"^^xsd:string) Annotation( "RHEA:14864"^^xsd:string) "Catalysis of the reaction: (S)-dihydroorotate + NADP(+) = H(+) + NADPH + orotate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.58"^^xsd:string) "orsellinate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.58"^^xsd:string) "orsellinate carboxy-lyase (orcinol-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.58"^^xsd:string) Annotation( "RHEA:16736"^^xsd:string) "Catalysis of the reaction: o-orsellinate + H(+) = CO(2) + orcinol."^^xsd:string) AnnotationAssertion(rdfs:label "orsellinate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "orsellinate-depside hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.40"^^xsd:string) "lecanorate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.40"^^xsd:string) Annotation( "RHEA:19552"^^xsd:string) "Catalysis of the reaction: H(2)O + orsellinate depside = 2 o-orsellinate + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.3.2"^^xsd:string) "oxalate coenzyme A-transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "succinyl-CoA:oxalate CoA-transferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.2"^^xsd:string) Annotation( "RHEA:23591"^^xsd:string) "Catalysis of the reaction: oxalate + succinyl-CoA = oxalyl-CoA + succinate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.2"^^xsd:string) "succinyl-CoA:oxalate CoA-transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.2"^^xsd:string) "succinyl-beta-ketoacyl-CoA transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.3.2"^^xsd:string) "oxalate CoA-transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.3.4"^^xsd:string) Annotation( "RHEA:21881"^^xsd:string) "Catalysis of the reaction: 2 H(+) + O(2) + oxalate = 2 CO(2) + H(2)O(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.4"^^xsd:string) "oxalic acid oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.4"^^xsd:string) "oxalate:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oxalate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.4"^^xsd:string) "aero-oxalo dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.2.2"^^xsd:string) "oxalacetic keto-enol isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oxaloacetate tautomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.2.2"^^xsd:string) "oxaloacetate keto-enol-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.2.2"^^xsd:string) Annotation( "RHEA:16024"^^xsd:string) "Catalysis of the reaction: oxaloacetate = enol-oxaloacetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.2.2"^^xsd:string) "oxaloacetate keto-enol tautomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxoglutarate dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.52"^^xsd:string) "2-oxoglutarate:NADP+ 2-oxidoreductase (CoA-succinylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.52"^^xsd:string) Annotation( "RHEA:21403"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + CoA + NADP(+) = CO(2) + NADPH + succinyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.34"^^xsd:string) Annotation( "MetaCyc:PANTETHEINE-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + pantetheine = ADP + pantetheine 4'-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.34"^^xsd:string) "pantetheine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.34"^^xsd:string) "ATP:pantetheine 4'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pantetheine kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.106"^^xsd:string) "panthothenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.106"^^xsd:string) "(R)-pantoate:NAD+ 4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pantoate 4-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.106"^^xsd:string) "pantoate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.106"^^xsd:string) Annotation( "RHEA:23003"^^xsd:string) "Catalysis of the reaction: (R)-pantoate + NAD(+) = (R)-4-dehydropantoate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.106"^^xsd:string) "D-pantoate:NAD+ 4-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.30"^^xsd:string) "pantothenylcysteine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.30"^^xsd:string) "N-[(R)-pantothenoyl]-L-cysteine carboxy-lyase (pantetheine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.30"^^xsd:string) Annotation( "RHEA:15080"^^xsd:string) "Catalysis of the reaction: N-[(R)-pantothenoyl]-L-cysteine + H(+) = (R)-pantetheine + CO(2)."^^xsd:string) AnnotationAssertion(rdfs:label "pantothenoylcysteine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.30"^^xsd:string) "N-[(R)-pantothenoyl]-L-cysteine carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.30"^^xsd:string) "N-((R)-pantothenoyl)-L-cysteine carboxy-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.50"^^xsd:string) "pentanamide amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.50"^^xsd:string) Annotation( "RHEA:10003"^^xsd:string) "Catalysis of the reaction: H(2)O + pentanamide = NH(4)(+) + valerate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.50"^^xsd:string) "valeramidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pentanamidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.26"^^xsd:string) "peptidyltryptophan 2,3-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.26"^^xsd:string) "peptide-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.26"^^xsd:string) "pyrrolooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.26"^^xsd:string) "tryptophan pyrrolooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.26"^^xsd:string) Annotation( "MetaCyc:PEPTIDE-TRYPTOPHAN-23-DIOXYGENASE-RXN"^^xsd:string) "Catalysis of the reaction: peptide tryptophan + O2 = peptide formylkynurenine."^^xsd:string) AnnotationAssertion(rdfs:label "peptide-tryptophan 2,3-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.43"^^xsd:string) Annotation( "MetaCyc:PEPTIDYL-GLUTAMINASE-RXN"^^xsd:string) "Catalysis of the reaction: alpha-N-peptidyl-L-glutamine + H2O = alpha-N-peptidyl-L-glutamate + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.43"^^xsd:string) "peptidoglutaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.43"^^xsd:string) "peptidoglutaminase I activity"^^xsd:string) AnnotationAssertion(rdfs:label "peptidyl-glutaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.43"^^xsd:string) "peptideglutaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.43"^^xsd:string) "peptidyl-L-glutamine amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.35"^^xsd:string) "UDPglucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phenol beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "phenol b-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.35"^^xsd:string) "UDPglucose:phenol beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.35"^^xsd:string) "uridine diphosphoglucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.35"^^xsd:string) "UDP-glucose:phenol beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.35"^^xsd:string) "UDP glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.35"^^xsd:string) Annotation( "MetaCyc:PHENOL-BETA-GLUCOSYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: UDP-glucose + a phenol = UDP + an aryl beta-D-glucoside."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.35"^^xsd:string) "UDP-glucose glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.35"^^xsd:string) "phenol-beta-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.12.9"^^xsd:string) "phenylalanine (deaminating, decarboxylating)oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.9"^^xsd:string) Annotation( "RHEA:10715"^^xsd:string) "Catalysis of the reaction: L-phenylalanine + O(2) = 2-phenylacetamide + CO(2) + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.9"^^xsd:string) "L-phenylalanine oxidase (deaminating and decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.9"^^xsd:string) "L-phenylalanine:oxygen 2-oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.9"^^xsd:string) "l-phenylalanine oxidase (deaminating and decarboxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.9"^^xsd:string) "phenylalanine (deaminating, decarboxylating) oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phenylalanine 2-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phenylalanine adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.54"^^xsd:string) "ATP:L-phenylalanine adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.54"^^xsd:string) Annotation( "RHEA:17192"^^xsd:string) "Catalysis of the reaction: L-phenylalanine + ATP = N-adenylyl-L-phenylalanine + diphosphate + 2 H(+)."^^xsd:string) AnnotationAssertion( "ATP:phenylalanine adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.54"^^xsd:string) "L-phenylalanine adenylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.53"^^xsd:string) Annotation( "MetaCyc:PHENYLALANINE-DECARBOXYLASE-RXN"^^xsd:string) "Catalysis of the reaction: L-phenylalanine = phenylethylamine + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.53"^^xsd:string) "L-phenylalanine decarboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phenylalanine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.53"^^xsd:string) "L-phenylalanine carboxy-lyase (phenylethylamine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.53"^^xsd:string) "aromatic L-amino acid decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.53"^^xsd:string) "L-phenylalanine carboxy-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.1.20"^^xsd:string) "PHD"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.20"^^xsd:string) Annotation( "MetaCyc:PHENYLALANINE-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: L-phenylalanine + H2O + NAD+ = phenylpyruvate + NH3 + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "phenylalanine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.20"^^xsd:string) "L-phenylalanine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.20"^^xsd:string) "L-phenylalanine:NAD+ oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.20"^^xsd:string) "PheDH activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phenylalanine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.53"^^xsd:string) "acetyl-CoA:L-phenylalanine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.53"^^xsd:string) "acetyl-CoA-L-phenylalanine alpha-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.53"^^xsd:string) Annotation( "RHEA:17804"^^xsd:string) "Catalysis of the reaction: L-phenylalanine + acetyl-CoA = N-acetyl-L-phenylalanine + CoA + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.43"^^xsd:string) "phenylpyruvate carboxy-lyase (phenylacetaldehyde-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.43"^^xsd:string) Annotation( "MetaCyc:PHENYLPYRUVATE-DECARBOXYLASE-RXN"^^xsd:string) "Catalysis of the reaction: phenylpyruvate = phenylacetaldehyde + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.43"^^xsd:string) "phenylpyruvate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phenylpyruvate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.2.1"^^xsd:string) "phenylpyruvic keto--enol isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phenylpyruvate tautomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.2.1"^^xsd:string) "phenylpyruvate keto-enol-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.2.1"^^xsd:string) Annotation( "MetaCyc:PHENYLPYRUVATE-TAUTOMERASE-RXN"^^xsd:string) "Catalysis of the reaction: keto-phenylpyruvate = enol-phenylpyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.2.1"^^xsd:string) "phenylpyruvate keto--enol tautomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.26"^^xsd:string) Annotation( "RHEA:21715"^^xsd:string) "Catalysis of the reaction: L-threo-3-phenylserine = benzaldehyde + glycine."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.26"^^xsd:string) "L-threo-3-phenylserine benzaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.26"^^xsd:string) "L-threo-3-phenylserine benzaldehyde-lyase (glycine-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "phenylserine aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.7.1.4"^^xsd:string) "lactase-phlorizin hydrolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.4"^^xsd:string) Annotation( "RHEA:23399"^^xsd:string) "Catalysis of the reaction: H(2)O + phloretin = H(+) + phloretate + phloroglucinol."^^xsd:string) AnnotationAssertion(rdfs:label "phloretin hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.7.1.4"^^xsd:string) "2',4,4',6'-tetrahydroxydehydrochalcone 1,3,5-trihydroxybenzenehydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.51"^^xsd:string) "diacylphorbate 12-hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.51"^^xsd:string) Annotation( "RHEA:21319"^^xsd:string) "Catalysis of the reaction: H(2)O + phorbol 12,13-dibutanoate = butanoate + H(+) + phorbol 13-butanoate."^^xsd:string) AnnotationAssertion(rdfs:label "phorbol-diester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.51"^^xsd:string) "PDEH"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.51"^^xsd:string) "phorbol-12,13-diester 12-ester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.51"^^xsd:string) "12,13-diacylphorbate 12-acylhydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.19"^^xsd:string) "phosphotransbutyrylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.19"^^xsd:string) Annotation( "RHEA:20895"^^xsd:string) "Catalysis of the reaction: butanoyl-CoA + phosphate = butanoyl phosphate + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.19"^^xsd:string) "butanoyl-CoA:phosphate butanoyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphate butyryltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.26"^^xsd:string) "1-acyl-2-oleoyl-sn-glycero-3-phosphocholine,NADH:oxygen oxidoreductase (12-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.26"^^xsd:string) "oleate delta12-monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylcholine 12-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.26"^^xsd:string) "oleate Delta(12)-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.26"^^xsd:string) "ricinoleic acid synthase activity"^^xsd:string) AnnotationAssertion( "oleate D12-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.26"^^xsd:string) "oleate delta12-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.26"^^xsd:string) Annotation( "RHEA:11371"^^xsd:string) "Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + H(+) + NADH + O(2) = 1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + H(2)O + NAD(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.35"^^xsd:string) "oleoyl-CoA desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.35"^^xsd:string) "oleate desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.35"^^xsd:string) Annotation( "RHEA:12567"^^xsd:string) "Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + NAD(+) = 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + H(+) + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylcholine desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.35"^^xsd:string) "1-acyl-2-oleoyl-sn-glycero-3-phosphocholine:NAD+ delta12-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.35"^^xsd:string) "linoleate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.35"^^xsd:string) "oleoylphosphatidylcholine desaturase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidylinositol deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.52"^^xsd:string) Annotation( "RHEA:18004"^^xsd:string) "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + H(2)O = 1-acyl-sn-glycero-3-phospho-D-myo-inositol + a carboxylate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.52"^^xsd:string) "1-phosphatidyl-D-myo-inositol 2-acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.52"^^xsd:string) "phosphatidylinositol phospholipase A2 activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphoadenylylsulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.2.2"^^xsd:string) "PAPS sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.2.2"^^xsd:string) "3-phosphoadenylyl sulfatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.2.2"^^xsd:string) Annotation( "MetaCyc:PHOSPHOADENYLYLSULFATASE-RXN"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + H2O = adenosine 3',5'-bisphosphate + sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.2.2"^^xsd:string) "3-phosphoadenosine 5-phosphosulfate sulfatase activity"^^xsd:string) AnnotationAssertion( "phosphoadenylylsulphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.2.2"^^xsd:string) "3'-phosphoadenylylsulfate sulfohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphoamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.9.1.1"^^xsd:string) Annotation( "RHEA:12980"^^xsd:string) "Catalysis of the reaction: N-phosphocreatine + H(2)O = creatine + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.9.1.1"^^xsd:string) "creatine phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.9.1.1"^^xsd:string) "phosphamide hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.2.9"^^xsd:string) "PEP mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.9"^^xsd:string) "phosphoenolpyruvate phosphomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.9"^^xsd:string) "phosphoenolpyruvate 2,3-phosphonomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.9"^^xsd:string) Annotation( "RHEA:17016"^^xsd:string) "Catalysis of the reaction: phosphoenolpyruvate = 3-phosphonopyruvate."^^xsd:string) AnnotationAssertion(rdfs:label "phosphoenolpyruvate mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.9"^^xsd:string) "phosphoenolpyruvate-phosphonopyruvate phosphomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.9"^^xsd:string) "PEP phosphomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.2.9"^^xsd:string) "PEPPM"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.60"^^xsd:string) "PEP phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.60"^^xsd:string) "phosphoenolpyruvate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.60"^^xsd:string) Annotation( "RHEA:20000"^^xsd:string) "Catalysis of the reaction: H(2)O + phosphoenolpyruvate = phosphate + pyruvate."^^xsd:string) AnnotationAssertion(rdfs:label "phosphoenolpyruvate phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.10"^^xsd:string) "ATP:alpha-D-glucose-1-phosphate 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.10"^^xsd:string) Annotation( "RHEA:13380"^^xsd:string) "Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = alpha-D-glucose 1,6-bisphosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.10"^^xsd:string) "ATP:D-glucose-1-phosphate 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.10"^^xsd:string) "phosphoglucokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.10"^^xsd:string) "glucose-phosphate kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoglucokinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphoglycerate kinase (GTP) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.10"^^xsd:string) "GTP:3-phospho-D-glycerate 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.2.10"^^xsd:string) Annotation( "RHEA:23335"^^xsd:string) "Catalysis of the reaction: 3-phospho-D-glycerate + GTP = 3-phospho-D-glyceroyl phosphate + GDP + H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.20"^^xsd:string) "D-glycerate-2-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.20"^^xsd:string) "D-2-phosphoglycerate phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoglycerate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.20"^^xsd:string) Annotation( "RHEA:21159"^^xsd:string) "Catalysis of the reaction: 2-phospho-D-glycerate + H(2)O = D-glycerate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.20"^^xsd:string) "glycerophosphate phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.9"^^xsd:string) "xylulose-5-phosphate phosphoketolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.9"^^xsd:string) "D-xylulose-5-phosphate D-glyceraldehyde-3-phosphate-lyase (phosphate-acetylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.9"^^xsd:string) "D-xylulose-5-phosphate D-glyceraldehyde-3-phosphate-lyase (adding phosphate; acetyl-phosphate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoketolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.9"^^xsd:string) Annotation( "MetaCyc:PHOSPHOKETOLASE-RXN"^^xsd:string) "Catalysis of the reaction: D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.11.1.1"^^xsd:string) "2-oxoethylphosphonate phosphonohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.11.1.1"^^xsd:string) "phosphonatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphonoacetaldehyde hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.11.1.1"^^xsd:string) "phosphonoacetylaldehyde phosphonohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.11.1.1"^^xsd:string) "2-phosphonoacetylaldehyde phosphonohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.11.1.1"^^xsd:string) Annotation( "RHEA:18908"^^xsd:string) "Catalysis of the reaction: H(2)O + phosphonoacetaldehyde = acetaldehyde + H(+) + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.18"^^xsd:string) "phosphoribokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoribokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.18"^^xsd:string) "ATP:D-ribose-5-phosphate 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.18"^^xsd:string) Annotation( "RHEA:21219"^^xsd:string) "Catalysis of the reaction: D-ribose 5-phosphate + ATP = D-ribose 1,5-diphosphate + ADP + 2 H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.17"^^xsd:string) "protein phosphatase C"^^xsd:string) AnnotationAssertion( "phosphorylase phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.17"^^xsd:string) "glycogen phosphorylase phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.17"^^xsd:string) "type 1 protein phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[phosphorylase] phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.17"^^xsd:string) "phosphorylase a phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.17"^^xsd:string) Annotation( "MetaCyc:PHOSPHORYLASE-PHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: [phosphorylase a] + 4 H2O = 2 [phosphorylase b] + 4 phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.17"^^xsd:string) "PR-enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.17"^^xsd:string) "phosphorylase a phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.24"^^xsd:string) "phytanate:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "phytanate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.24"^^xsd:string) Annotation( "RHEA:21383"^^xsd:string) "Catalysis of the reaction: ATP + CoA + phytanate = AMP + diphosphate + H(+) + phytanoyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.24"^^xsd:string) "phytanoyl-CoA ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pinosylvin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.146"^^xsd:string) Annotation( "RHEA:12555"^^xsd:string) "Catalysis of the reaction: trans-cinnamoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4 CO(2) + 4 CoA + pinosylvin."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.146"^^xsd:string) "malonyl-CoA:cinnamoyl-CoA malonyltransferase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.146"^^xsd:string) "stilbene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.146"^^xsd:string) "pine stilbene synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.145"^^xsd:string) "(E,E)-piperoyl-CoA:piperidine N-piperoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.145"^^xsd:string) "piperidine piperoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.145"^^xsd:string) "piperoyl-CoA:piperidine N-piperoyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "piperidine N-piperoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.145"^^xsd:string) Annotation( "RHEA:14564"^^xsd:string) "Catalysis of the reaction: (E,E)-piperoyl-CoA + piperidine = N-[(E,E)-piperoyl]piperidine + CoA + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.25"^^xsd:string) "lysoplasmenylcholine acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.25"^^xsd:string) "acyl-CoA:1-O-alk-1-enyl-glycero-3-phosphocholine 2-O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.25"^^xsd:string) "O-1-alkenylglycero-3-phosphorylcholine acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "plasmalogen synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.25"^^xsd:string) Annotation( "MetaCyc:PLASMALOGEN-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: acyl-CoA + 1-O-alk-1-enyl-glycero-3-phosphocholine = CoA + plasmenylcholine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.25"^^xsd:string) "1-alkenyl-glycero-3-phosphorylcholine:acyl-CoA acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fucokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.52"^^xsd:string) "ATP:beta-L-fucose 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.52"^^xsd:string) "ATP:6-deoxy-L-galactose 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.52"^^xsd:string) "L-fucose kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.52"^^xsd:string) "L-fucokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.52"^^xsd:string) Annotation( "RHEA:13244"^^xsd:string) "Catalysis of the reaction: L-fucose + ATP = beta-L-fucose 1-phosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.52"^^xsd:string) "fucose kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.52"^^xsd:string) "fucokinase (phosphorylating) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.87"^^xsd:string) "octopamine hydro-lyase [deaminating; (4-hydroxyphenyl)acetaldehyde-forming]"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.87"^^xsd:string) Annotation( "RHEA:18176"^^xsd:string) "Catalysis of the reaction: 1-(4-hydroxyphenyl)-2-aminoethanol = (4-hydroxyphenyl)acetaldehyde + NH(4)(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.87"^^xsd:string) "octopamine hydro-lyase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.87"^^xsd:string) "octopamine hydrolyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "octopamine dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.2.1.8"^^xsd:string) "oxalyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oxalate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.8"^^xsd:string) "oxalate:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.8"^^xsd:string) "oxalyl coenzyme A synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.8"^^xsd:string) Annotation( "RHEA:18296"^^xsd:string) "Catalysis of the reaction: ATP + CoA + oxalate = AMP + diphosphate + H(+) + oxalyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.3.13"^^xsd:string) "3-oxalomalate glyoxylate-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.13"^^xsd:string) Annotation( "RHEA:22035"^^xsd:string) "Catalysis of the reaction: 3-oxalomalate = glyoxylate + oxaloacetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.3.13"^^xsd:string) "3-oxalomalate glyoxylate-lyase (oxaloacetate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "oxalomalate lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.3.5"^^xsd:string) "oxamic transcarbamylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.5"^^xsd:string) Annotation( "RHEA:22987"^^xsd:string) "Catalysis of the reaction: carbamoyl phosphate + oxamate = oxalurate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.5"^^xsd:string) "carbamoyl-phosphate:oxamate carbamoyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oxamate carbamoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.3.1"^^xsd:string) Annotation( "RHEA:11627"^^xsd:string) "Catalysis of the reaction: 2-(hydroxyimino)propanoate + acetone = acetone oxime + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.3.1"^^xsd:string) "pyruvate-acetone oximinotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "oximinotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.3.1"^^xsd:string) "transoximase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.3.1"^^xsd:string) "oximase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.3.1"^^xsd:string) "transoximinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.3.1"^^xsd:string) "pyruvate-oxime:acetone oximinotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.19"^^xsd:string) "dehydrogenase, alkyl-acylglycerophosphorylethanolamine"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.19"^^xsd:string) "alkylacylglycerophosphoethanolamine desaturase activity"^^xsd:string) AnnotationAssertion( "plasmenylethanolamine desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.19"^^xsd:string) Annotation( "MetaCyc:PLASMANYLETHANOLAMINE-DESATURASE-RXN"^^xsd:string) "Catalysis of the reaction: O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + donor-H2 + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + acceptor + 2 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.19"^^xsd:string) "1-O-alkyl-2-acyl-sn-glycero-3-phosphorylethanolamine desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.19"^^xsd:string) "alkylacylglycero-phosphorylethanolamine dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "plasmanylethanolamine desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.19"^^xsd:string) "1-O-alkyl 2-acyl-sn-glycero-3-phosphorylethanolamine desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.19"^^xsd:string) "O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine,hydrogen-donor:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.136"^^xsd:string) Annotation( "MetaCyc:POLYSIALIC-ACID-O-ACETYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + an alpha-2,8-linked polymer of sialic acid = CoA + polysialic acid acetylated at O-7 or O-9."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.136"^^xsd:string) "LRAT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.136"^^xsd:string) "acetyl-CoA:polysialic-acid O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "polysialic-acid O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.136"^^xsd:string) "lecithin:retinol acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.136"^^xsd:string) "retinyl ester synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.136"^^xsd:string) "lecithin retinol acyl transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.30"^^xsd:string) "dehydrogenase, polyvinyl alcohol"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.30"^^xsd:string) "PVA oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.30"^^xsd:string) Annotation( "MetaCyc:POLYVINYL-ALCOHOL-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: polyvinyl alcohol + O2 = oxidized polyvinyl alcohol + H2O2."^^xsd:string) AnnotationAssertion(rdfs:label "polyvinyl-alcohol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.30"^^xsd:string) "polyvinyl-alcohol:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "prenyl-diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.7.1"^^xsd:string) Annotation( "MetaCyc:PRENYL-PYROPHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: prenyl diphosphate + H2O = prenol + diphosphate."^^xsd:string) AnnotationAssertion( "prenyl-pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.7.1"^^xsd:string) "prenol pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.7.1"^^xsd:string) "prenyl-diphosphate diphosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.7.1"^^xsd:string) "prenylphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.50"^^xsd:string) "UDP galactose-collagen galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.50"^^xsd:string) "UDPgalactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.50"^^xsd:string) "UDP-galactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.50"^^xsd:string) "hydroxylysine galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.50"^^xsd:string) "collagen galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.50"^^xsd:string) "collagen hydroxylysyl galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.50"^^xsd:string) Annotation( "MetaCyc:PROCOLLAGEN-GALACTOSYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: UDP-galactose + procollagen 5-hydroxy-L-lysine = UDP + procollagen 5-(D-galactosyloxy)-L-lysine."^^xsd:string) AnnotationAssertion(rdfs:label "procollagen galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.50"^^xsd:string) "uridine diphosphogalactose-collagen galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.50"^^xsd:string) "UDPgalactose:5-hydroxylysine-collagen galactosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.14"^^xsd:string) "progesterone 11alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion( "progesterone 11a-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.14"^^xsd:string) "progesterone,hydrogen-donor:oxygen oxidoreductase (11alpha-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.14"^^xsd:string) "progesterone 11-alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.14"^^xsd:string) "progesterone 11alpha-monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "progesterone 11-alpha-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.14"^^xsd:string) Annotation( "RHEA:18208"^^xsd:string) "Catalysis of the reaction: AH(2) + O(2) + progesterone = 11alpha-hydroxyprogesterone + A + H(2)O."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.30"^^xsd:string) Annotation( "MetaCyc:PROGESTERONE-5-ALPHA-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: 5-alpha-pregnan-3,20-dione + NADP+ = progesterone + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.30"^^xsd:string) "5alpha-pregnan-3,20-dione:NADP+ 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "progesterone 5-alpha-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.30"^^xsd:string) "steroid 5-alpha-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.30"^^xsd:string) "progesterone 5alpha-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.30"^^xsd:string) "delta4-steroid 5alpha-reductase (progesterone)"^^xsd:string) AnnotationAssertion( "progesterone 5a-reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.4"^^xsd:string) "progesterone hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "progesterone monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.4"^^xsd:string) "progesterone,hydrogen-donor:oxygen oxidoreductase (hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.4"^^xsd:string) Annotation( "RHEA:11987"^^xsd:string) "Catalysis of the reaction: AH(2) + O(2) + progesterone = A + H(2)O + testosterone acetate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.28"^^xsd:string) "dioldehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.28"^^xsd:string) "diol dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.28"^^xsd:string) "DL-1,2-propanediol hydro-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "propanediol dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.28"^^xsd:string) "coenzyme B12-dependent diol dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.28"^^xsd:string) "propane-1,2-diol hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.28"^^xsd:string) Annotation( "RHEA:14572"^^xsd:string) "Catalysis of the reaction: propane-1,2-diol = H(2)O + propanal."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.28"^^xsd:string) "propanediol dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.28"^^xsd:string) "adenosylcobalamin-dependent diol dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.28"^^xsd:string) "diol dehydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.28"^^xsd:string) "1,2-propanediol dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.28"^^xsd:string) "propane-1,2-diol hydro-lyase (propanal-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.28"^^xsd:string) "meso-2,3-butanediol dehydrase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "propanediol-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.7"^^xsd:string) Annotation( "RHEA:21587"^^xsd:string) "Catalysis of the reaction: NAD(+) + propane-1,2-diol 1-phosphate = H(+) + hydroxyacetone phosphate + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.35"^^xsd:string) "4-hydroxy-3-hexanone propanal-lyase (propanal-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.35"^^xsd:string) "4-hydroxy-3-hexanone aldolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "propioin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.35"^^xsd:string) Annotation( "RHEA:11103"^^xsd:string) "Catalysis of the reaction: 4-hydroxyhexan-3-one = 2 propanal."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.35"^^xsd:string) "4-hydroxy-3-hexanone propanal-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "propionate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.17"^^xsd:string) "propanoate:CoA ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.17"^^xsd:string) "propionyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.17"^^xsd:string) Annotation( "MetaCyc:PROPIONATE--COA-LIGASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "prostaglandin-A1 delta-isomerase activity"^^xsd:string) AnnotationAssertion( "prostaglandin-A1 D-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.9"^^xsd:string) "(13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate delta10-delta11-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.9"^^xsd:string) Annotation( "RHEA:10463"^^xsd:string) "Catalysis of the reaction: prostaglandin A1 = prostaglandin C1."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.9"^^xsd:string) "prostaglandin A isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.99.3"^^xsd:string) "PGH-PGE isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.3"^^xsd:string) "(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.3"^^xsd:string) "endoperoxide isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.3"^^xsd:string) "prostaglandin H-E isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.3"^^xsd:string) Annotation( "RHEA:12896"^^xsd:string) "Catalysis of the reaction: prostaglandin H(2) = prostaglandin E(2)."^^xsd:string) AnnotationAssertion(rdfs:label "prostaglandin-E synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.3"^^xsd:string) "PGE2 isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.3"^^xsd:string) "PGE isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.3"^^xsd:string) "prostaglandin-H2 E-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.3"^^xsd:string) "prostaglandin R-prostaglandin E isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.3"^^xsd:string) "prostaglandin endoperoxide E isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.3"^^xsd:string) "Prostaglandin-H(2) E-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.3"^^xsd:string) "prostaglandin endoperoxide E2 isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.189"^^xsd:string) "9-keto-prostaglandin E2 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.189"^^xsd:string) "prostaglandin E 9-ketoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.189"^^xsd:string) "9-keto-prostaglandin E(2) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.189"^^xsd:string) "prostaglandin E2-9-oxoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.189"^^xsd:string) "PGE(2) 9-ketoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.189"^^xsd:string) "prostaglandin-E(2) 9-oxoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.189"^^xsd:string) "PGE2 9-ketoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.189"^^xsd:string) "PGE2-9-OR"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.189"^^xsd:string) Annotation( "MetaCyc:PROSTAGLANDIN-E2-9-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate + NADP+ = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.189"^^xsd:string) "9-ketoprostaglandin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.189"^^xsd:string) "PGE-9-ketoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.189"^^xsd:string) "PGE2-9-ketoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.189"^^xsd:string) "PGE(2) 9-oxoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.189"^^xsd:string) "PGE2 9-oxoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.189"^^xsd:string) "(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 9-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.189"^^xsd:string) "reductase, 15-hydroxy-9-oxoprostaglandin"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.189"^^xsd:string) "prostaglandin-E2 9-oxoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "prostaglandin-E2 9-reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.63"^^xsd:string) "3,4-dihydrobenzoate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.63"^^xsd:string) Annotation( "RHEA:22419"^^xsd:string) "Catalysis of the reaction: 3,4-dihydroxybenzoate + H(+) = catechol + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.63"^^xsd:string) "protocatechuate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.63"^^xsd:string) "3,4-dihydroxybenzoate decarboxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protocatechuate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.63"^^xsd:string) "3,4-dihydroxybenzoate carboxy-lyase (catechol-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.118"^^xsd:string) "prunasin hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "prunasin beta-glucosidase activity"^^xsd:string) AnnotationAssertion( "prunasin b-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.118"^^xsd:string) "prunasin beta-D-glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.118"^^xsd:string) Annotation( "RHEA:16492"^^xsd:string) "Catalysis of the reaction: (R)-prunasin + H(2)O = D-glucose + mandelonitrile."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.83"^^xsd:string) Annotation( "RHEA:22451"^^xsd:string) "Catalysis of the reaction: ATP + pseudouridine = ADP + 2 H(+) + pseudouridine 5'-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.83"^^xsd:string) "pseudouridine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "pseudouridine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.83"^^xsd:string) "ATP:pseudouridine 5'-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "psychosine sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.13"^^xsd:string) Annotation( "MetaCyc:PSYCHOSINE-SULFOTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + galactosylsphingosine = adenosine 3',5'-bisphosphate + psychosine sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.13"^^xsd:string) "PAPS:psychosine sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.13"^^xsd:string) "3'-phosphoadenosine 5'-phosphosulfate-psychosine sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.13"^^xsd:string) "3'-phosphoadenylyl-sulfate:galactosylsphingosine sulfotransferase activity"^^xsd:string) AnnotationAssertion( "psychosine sulphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pteridine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.1"^^xsd:string) "2-amino-4-hydroxypteridine:oxygen oxidoreductase (7-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.1"^^xsd:string) Annotation( "MetaCyc:PTERIDINE-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: 2-amino-4-hydroxypteridine + O2 = 2-amino-4,7-dihydroxypteridine + unknown."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.11"^^xsd:string) "2-amino-4-hydroxypteridine aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.11"^^xsd:string) Annotation( "MetaCyc:PTERIN-DEAMINASE-RXN"^^xsd:string) "Catalysis of the reaction: 2-amino-4-hydroxypteridine + H2O = 2,4-dihydroxypteridine + NH3."^^xsd:string) AnnotationAssertion(rdfs:label "pterin deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.11"^^xsd:string) "acrasinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.246"^^xsd:string) "medicarpin:NADP+ 2'-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.246"^^xsd:string) "pterocarpan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.246"^^xsd:string) Annotation( "MetaCyc:PTEROCARPIN-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: medicarpin + NADP+ = vestitone + NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "pterocarpin synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.2.4"^^xsd:string) Annotation( "MetaCyc:PURINE-IMIDAZOLE-RING-CYCLASE-RXN"^^xsd:string) "Catalysis of the reaction: DNA 4,6-diamino-5-formamidopyrimidine = DNA adenine + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.4"^^xsd:string) "DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing; DNA-adenine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.4"^^xsd:string) "DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.4"^^xsd:string) "DNA-4,6-diamino-5-formamidopyrimidine C8-N9-lyase (cyclizing; DNA-adenine-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "purine imidazole-ring cyclase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.3.6"^^xsd:string) "putrescine transcarbamylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.6"^^xsd:string) Annotation( "RHEA:21939"^^xsd:string) "Catalysis of the reaction: carbamoyl phosphate + putrescine = N-carbamoylputrescine + H(+) + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "putrescine carbamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.6"^^xsd:string) "putrescine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.6"^^xsd:string) "carbamoyl-phosphate:putrescine carbamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.3.6"^^xsd:string) "PTCase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.3.10"^^xsd:string) Annotation( "MetaCyc:PUTRESCINE-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: putrescine + O2 + H2O = 4-aminobutanal + NH3 + H2O2."^^xsd:string) AnnotationAssertion(rdfs:label "putrescine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.10"^^xsd:string) "putrescine:oxygen oxidoreductase (deaminating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.10"^^xsd:string) "pyranose-2-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.10"^^xsd:string) "glucose 2-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.10"^^xsd:string) Annotation( "RHEA:10555"^^xsd:string) "Catalysis of the reaction: D-glucose + O(2) = 2-dehydro-D-glucose + H(2)O(2)."^^xsd:string) AnnotationAssertion(rdfs:label "pyranose oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.10"^^xsd:string) "pyranose:oxygen 2-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.50"^^xsd:string) "L-serine hydro-lyase (adding pyrazole)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.50"^^xsd:string) "L-serine hydro-lyase [adding pyrazole; 3-(pyrazol-1-yl)-L-alanine-forming]"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.50"^^xsd:string) Annotation( "RHEA:24515"^^xsd:string) "Catalysis of the reaction: L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + H(2)O."^^xsd:string) AnnotationAssertion(rdfs:label "pyrazolylalanine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.50"^^xsd:string) "beta-pyrazolylalaninase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.107"^^xsd:string) "pyridoxal dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.107"^^xsd:string) Annotation( "RHEA:21339"^^xsd:string) "Catalysis of the reaction: NAD(+) + pyridoxal = 4-pyridoxolactone + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.107"^^xsd:string) "pyridoxal:NAD+ 4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyridoxal 4-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.65"^^xsd:string) "pyridoxine:NADP 4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.65"^^xsd:string) Annotation( "RHEA:16132"^^xsd:string) "Catalysis of the reaction: NADP(+) + pyridoxine = H(+) + NADPH + pyridoxal."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.65"^^xsd:string) "pyridoxol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.65"^^xsd:string) "pyridoxine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.65"^^xsd:string) "pyridoxin dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyridoxine:NADP 4-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.65"^^xsd:string) "PL reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.65"^^xsd:string) "pyridoxal reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.12"^^xsd:string) "pyridoxine:oxygen 4-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyridoxine 4-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.12"^^xsd:string) "pyridoxol 4-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.12"^^xsd:string) "pyridoxin 4-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.12"^^xsd:string) Annotation( "MetaCyc:PYRIDOXINE-4-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: pyridoxine + O2 = pyridoxal + H2O2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyridoxine 5-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.9"^^xsd:string) "pyridoxine:acceptor 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.9"^^xsd:string) "pyridoxal-5-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.9"^^xsd:string) "pyridoxine:(acceptor) 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.9"^^xsd:string) Annotation( "MetaCyc:PYRIDOXINE-5-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: pyridoxine + acceptor = isopyridoxal + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.9"^^xsd:string) "pyridoxol 5-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.9"^^xsd:string) "pyridoxin 5-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.9"^^xsd:string) "pyridoxine 5'-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyrithiamine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.20"^^xsd:string) "1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium-bromide aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.20"^^xsd:string) Annotation( "MetaCyc:PYRITHIAMIN-DEAMINASE-RXN"^^xsd:string) "Catalysis of the reaction: 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + H2O = 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + NH3."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyrogallol 1,2-oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.35"^^xsd:string) Annotation( "RHEA:19676"^^xsd:string) "Catalysis of the reaction: O(2) + pyrogallol = (Z)-5-oxohex-2-enedioate + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.35"^^xsd:string) "1,2,3-trihydroxybenzene:oxygen 1,2-oxidoreductase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.35"^^xsd:string) "pyrogallol 1,2-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.1"^^xsd:string) Annotation( "MetaCyc:PYRROLINE-2-CARBOXYLATE-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: L-proline + NAD(P)+ = 1-pyrroline-2-carboxylate + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(rdfs:label "pyrroline-2-carboxylate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.1"^^xsd:string) "L-proline:NAD(P)+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.1"^^xsd:string) "delta1-pyrroline-2-carboxylate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.9.1"^^xsd:string) "PPDK"^^xsd:string) AnnotationAssertion(rdfs:label "pyruvate, phosphate dikinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.1"^^xsd:string) "ATP:pyruvate, phosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.1"^^xsd:string) "pyruvate-phosphate dikinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.1"^^xsd:string) "pyruvate-phosphate dikinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.1"^^xsd:string) "pyruvate, Pi dikinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.1"^^xsd:string) "pyruvate-phosphate ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.1"^^xsd:string) "pyruvate-inorganic phosphate dikinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.1"^^xsd:string) "pyruvate,orthophosphate dikinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.1"^^xsd:string) "pyruvic-phosphate dikinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.1"^^xsd:string) "pyruvate,phosphate dikinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.1"^^xsd:string) Annotation( "RHEA:10759"^^xsd:string) "Catalysis of the reaction: ATP + phosphate + pyruvate = AMP + diphosphate + 2 H(+) + phosphoenolpyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.1"^^xsd:string) "pyruvic-phosphate ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.1"^^xsd:string) "orthophosphate dikinase pyruvate"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyruvate dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.51"^^xsd:string) "pyruvate:NADP+ 2-oxidoreductase (CoA-acetylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.51"^^xsd:string) "pyruvate:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.51"^^xsd:string) "pyruvate:NADP(+) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.51"^^xsd:string) Annotation( "RHEA:17428"^^xsd:string) "Catalysis of the reaction: CoA + NADP(+) + pyruvate = acetyl-CoA + CO(2) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyruvate oxidase (CoA-acetylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.6"^^xsd:string) "pyruvate:oxygen 2-oxidoreductase (CoA-acetylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.6"^^xsd:string) Annotation( "RHEA:21915"^^xsd:string) "Catalysis of the reaction: CoA + H(+) + O(2) + pyruvate = acetyl-CoA + CO(2) + H(2)O(2)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.66"^^xsd:string) Annotation( "RHEA:17468"^^xsd:string) "Catalysis of the reaction: H(2)O + quercitrin = L-rhamnose + quercetin."^^xsd:string) AnnotationAssertion(rdfs:label "quercitrinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.66"^^xsd:string) "quercitrin 3-L-rhamnohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.43"^^xsd:string) "questin oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.43"^^xsd:string) "questin,NADPH:oxygen oxidoreductase (hydroxylating, anthraquinone-ring-opening)"^^xsd:string) AnnotationAssertion(rdfs:label "questin monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.43"^^xsd:string) Annotation( "RHEA:10839"^^xsd:string) "Catalysis of the reaction: H(+) + NADPH + O(2) + questin = demethylsulochrin + NADP(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.125"^^xsd:string) Annotation( "RHEA:14560"^^xsd:string) "Catalysis of the reaction: H(2)O + raucaffricine = D-glucose + vomilenine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.125"^^xsd:string) "raucaffricine beta-D-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.125"^^xsd:string) "raucaffricine glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.125"^^xsd:string) "raucaffricine beta-D-glucohydrolase activity"^^xsd:string) AnnotationAssertion( "raucaffricine b-glucosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "raucaffricine beta-glucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.12.5"^^xsd:string) "luciferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.5"^^xsd:string) "Renilla-type luciferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.5"^^xsd:string) "Renilla-luciferin:oxygen 2-oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "Renilla-luciferin 2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.5"^^xsd:string) "luciferase (Renilla luciferin)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.5"^^xsd:string) "aequorin activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.5"^^xsd:string) Annotation( "MetaCyc:RENILLA-LUCIFERIN-2-MONOOXYGENASE-RXN"^^xsd:string) "Catalysis of the reaction: Renilla luciferin + O2 = oxidized Renilla luciferin + CO2 + light."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.10"^^xsd:string) "3'-phosphoadenylyl-sulfate:Renilla luciferin sulfotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "Renilla-luciferin sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.10"^^xsd:string) "luciferin sulfokinase (3'-phosphoadenylyl sulfate:luciferin sulfotransferase)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.10"^^xsd:string) "luciferin sulfokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.10"^^xsd:string) "luciferin sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.10"^^xsd:string) Annotation( "RHEA:20484"^^xsd:string) "Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + Renilla luciferin = adenosine 3',5'-diphosphate + H(+) + luciferyl sulfate."^^xsd:string) AnnotationAssertion( "Renilla-luciferin sulphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.3.11"^^xsd:string) "retinene oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.11"^^xsd:string) "retinal:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "retinal oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.11"^^xsd:string) Annotation( "MetaCyc:RETINAL-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: retinal + O2 + H2O = retinoate + H2O2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.2.1.7"^^xsd:string) Annotation( "RHEA:19144"^^xsd:string) "Catalysis of the reaction: all-trans-retinol = 11-cis-retinol."^^xsd:string) AnnotationAssertion(rdfs:label "retinol isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.7"^^xsd:string) "all-trans-retinol 11-cis-trans-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.7"^^xsd:string) "all-trans-retinol isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "retinol O-fatty-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.76"^^xsd:string) "retinol fatty-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.76"^^xsd:string) "acyl-CoA:retinol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.76"^^xsd:string) "retinol acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.76"^^xsd:string) Annotation( "MetaCyc:RETINOL-O-FATTY-ACYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: acyl-CoA + retinol = CoA + retinyl ester."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.21"^^xsd:string) "retinyl palmitate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.21"^^xsd:string) "retinyl ester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RETINYL-PALMITATE-ESTERASE-RXN"^^xsd:string) Annotation( "RHEA:21511"^^xsd:string) "Catalysis of the reaction: retinyl palmitate + H2O = retinol + palmitate + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.21"^^xsd:string) "retinyl-palmitate palmitohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.21"^^xsd:string) "retinyl palmitate hydrolyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "retinyl-palmitate esterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.14"^^xsd:string) "ATP:rhodopsin phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.14"^^xsd:string) "STK14"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.14"^^xsd:string) "GRK1"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.14"^^xsd:string) "RK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.14"^^xsd:string) Annotation( "MetaCyc:RHODOPSIN-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + rhodopsin = ADP + phosphorhodopsin."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.14"^^xsd:string) "cone opsin kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.14"^^xsd:string) "GRK7"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.14"^^xsd:string) "rhodopsin kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "rhodopsin kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.14"^^xsd:string) "GPCR kinase 1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.14"^^xsd:string) "opsin kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.14"^^xsd:string) "opsin kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.14"^^xsd:string) "G-protein-coupled receptor kinase 1 activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.56"^^xsd:string) "ribitol dehydrogenase B (mutant enzyme with different properties)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.56"^^xsd:string) "adonitol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.56"^^xsd:string) "ribitol:NAD+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.56"^^xsd:string) "ribitol dehydrogenase D (mutant enzyme with different properties)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.56"^^xsd:string) "ribitol dehydrogenase A (wild type)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.56"^^xsd:string) Annotation( "RHEA:20056"^^xsd:string) "Catalysis of the reaction: D-ribitol + NAD(+) = D-ribulose + H(+) + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "ribitol 2-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.137"^^xsd:string) "dehydrogenase, ribitol 5-phosphate"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.137"^^xsd:string) "D-ribitol-5-phosphate:NAD(P)+ 2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.137"^^xsd:string) Annotation( "MetaCyc:RIBITOL-5-PHOSPHATE-2-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: D-ribitol 5-phosphate + NAD(P)+ = D-ribulose 5-phosphate + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(rdfs:label "ribitol-5-phosphate 2-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.42"^^xsd:string) Annotation( "RHEA:20412"^^xsd:string) "Catalysis of the reaction: alpha-D-glucose 1-phosphate + riboflavin = D-glucose + FMN."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.42"^^xsd:string) "G-1-P phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.42"^^xsd:string) "alpha-D-glucose-1-phosphate:riboflavin 5'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.42"^^xsd:string) "riboflavine phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "riboflavin phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.42"^^xsd:string) "D-glucose-1-phosphate:riboflavin 5'-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.99.1"^^xsd:string) Annotation( "RHEA:11411"^^xsd:string) "Catalysis of the reaction: H(2)O + H(+) + riboflavin = D-ribitol + lumichrome."^^xsd:string) AnnotationAssertion(rdfs:label "riboflavinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.1"^^xsd:string) "riboflavin hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.115"^^xsd:string) Annotation( "RHEA:11679"^^xsd:string) "Catalysis of the reaction: H(2)O + NADP(+) + ribofuranose = D-ribonate + 2 H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.115"^^xsd:string) "NADP-pentose-dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ribose 1-dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.115"^^xsd:string) "D-ribose:NADP+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.115"^^xsd:string) "D-ribose dehydrogenase (NADP+)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.4.7"^^xsd:string) "ribose 5-phosphate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.7"^^xsd:string) "ammonia-ribose 5-phosphate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.7"^^xsd:string) "ribose-5-phosphate:ammonia ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "ribose-5-phosphate-ammonia ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.7"^^xsd:string) "5-phosphoribosylamine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.4.7"^^xsd:string) Annotation( "RHEA:13780"^^xsd:string) "Catalysis of the reaction: D-ribose 5-phosphate + ATP + NH(4)(+) = 5-phospho-D-ribosylamine + ADP + 2 H(+) + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.1.20"^^xsd:string) "D-ribose isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.20"^^xsd:string) "D-ribose ketol-isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ribose isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.20"^^xsd:string) "D-ribose aldose-ketose-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.1.20"^^xsd:string) Annotation( "RHEA:20799"^^xsd:string) "Catalysis of the reaction: ribofuranose = D-ribulose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.22"^^xsd:string) Annotation( "RHEA:14020"^^xsd:string) "Catalysis of the reaction: N-ribosylnicotinamide + ATP = ADP + 2 H(+) + nicotinamide mononucleotide."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.22"^^xsd:string) "ATP:N-ribosylnicotinamide 5'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15137942"^^xsd:string) "nicotinamide riboside kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.22"^^xsd:string) "ribosylnicotinamide kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "ribosylnicotinamide kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.8"^^xsd:string) "N-ribosylpyrimidine ribohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.8"^^xsd:string) "pyrimidine nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.8"^^xsd:string) "N-ribosylpyrimidine nucleosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ribosylpyrimidine nucleosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.8"^^xsd:string) Annotation( "MetaCyc:RIBOSYLPYRIMIDINE-NUCLEOSIDASE-RXN"^^xsd:string) "Catalysis of the reaction: an N-D-ribosylpyrimidine + H2O = D-ribose + a pyrimidine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.8"^^xsd:string) "YeiK"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.8"^^xsd:string) "nucleoside ribohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.8"^^xsd:string) "pyrimidine-nucleoside ribohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.8"^^xsd:string) "RihB"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.10.3.6"^^xsd:string) "rifamycin B oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "rifamycin-B oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.6"^^xsd:string) "rifamycin-B:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion( "rifamycin-B-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.6"^^xsd:string) Annotation( "RHEA:11295"^^xsd:string) "Catalysis of the reaction: 2 H(+) + O(2) + rifamycin B = H(2)O(2) + rifamycin O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "UTP:RNA uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "polynucleotide uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.52"^^xsd:string) Annotation( "MetaCyc:RNA-URIDYLYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: UTP + RNA(n) = diphosphate + RNA(n+1)."^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "poly(U) polymerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "RNA uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.52"^^xsd:string) "terminal uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.52"^^xsd:string) "TUT activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.140"^^xsd:string) "rosmarinic acid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.140"^^xsd:string) "4-coumaroyl-CoA:4-hydroxyphenyllactic acid 4-coumaroyl transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "rosmarinate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.140"^^xsd:string) "caffeoyl-coenzyme A:3,4-dihydroxyphenyllactic acid caffeoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.140"^^xsd:string) Annotation( "MetaCyc:ROSMARINATE-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: caffeoyl-CoA + 3-(3,4-dihydroxyphenyl)lactate = CoA + rosmarinate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.140"^^xsd:string) "caffeoyl-CoA:3-(3,4-dihydroxyphenyl)lactate 2'-O-caffeoyl-transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.20"^^xsd:string) "rubber allyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.20"^^xsd:string) "rubber polymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.20"^^xsd:string) "rubber prenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.20"^^xsd:string) "cis-prenyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.20"^^xsd:string) "poly-cis-polyprenyl-diphosphate:isopentenyl-diphosphate polyprenylcistransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.20"^^xsd:string) "isopentenyl pyrophosphate cis-1,4-polyisoprenyl transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "rubber cis-polyprenylcistransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.20"^^xsd:string) "rubber transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.20"^^xsd:string) Annotation( "MetaCyc:RUBBER-CIS-POLYPRENYLCISTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: poly-cis-polyprenyl diphosphate + isopentenyl diphosphate = diphosphate + a poly-cis-polyprenyl diphosphate longer by one C5 unit."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.194"^^xsd:string) Annotation( "MetaCyc:RXN-1107"^^xsd:string) "Catalysis of the reaction: coniferyl alcohol + NADP+ = coniferyl aldehyde + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.194"^^xsd:string) "coniferyl-alcohol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "coniferyl-alcohol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.68"^^xsd:string) "coniferyl aldehyde:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.68"^^xsd:string) Annotation( "MetaCyc:RXN-1241"^^xsd:string) "Catalysis of the reaction: coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(rdfs:label "coniferyl-aldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.28"^^xsd:string) Annotation( "RHEA:20719"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-homocysteine + H(2)O + H(+) = S-inosyl-L-homocysteine + NH(4)(+)."^^xsd:string) AnnotationAssertion(rdfs:label "S-adenosylhomocysteine deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.28"^^xsd:string) "S-adenosyl-L-homocysteine aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.28"^^xsd:string) "adenosylhomocysteine deaminase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.6"^^xsd:string) "S-alkyl-L-cysteine sulfoxide lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.6"^^xsd:string) "S-alkyl-L-cysteine alkylthiol-lyase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.6"^^xsd:string) "S-alkylcysteinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.6"^^xsd:string) "S-alkyl-L-cysteine lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "S-alkylcysteine lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.6"^^xsd:string) "S-alkyl-L-cysteine alkylthiol-lyase (deaminating; pyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.6"^^xsd:string) Annotation( "MetaCyc:S-ALKYLCYSTEINE-LYASE-RXN"^^xsd:string) "Catalysis of the reaction: an S-alkyl-L-cysteine + H2O = an alkyl thiol + NH3 + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.6"^^xsd:string) "alkylcysteine lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.6"^^xsd:string) "S-alkyl-L-cysteinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.6"^^xsd:string) "alkyl cysteine lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.5.1.5"^^xsd:string) "S-carboxymethyl-L-cysteine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.5.1.5"^^xsd:string) "3-chloro-L-alanine chloride-lyase (adding thioglycolate; S-carboxymethyl-L-cysteine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.5.1.5"^^xsd:string) "3-chloro-L-alanine chloride-lyase (adding thioglycolate)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.5.1.5"^^xsd:string) Annotation( "RHEA:22871"^^xsd:string) "Catalysis of the reaction: 3-chloro-L-alanine + thioglycolate = S-carboxymethyl-L-cysteine + chloride + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "S-carboxymethylcysteine synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.2.13"^^xsd:string) Annotation( "RHEA:16716"^^xsd:string) "Catalysis of the reaction: S-succinylglutathione + H(2)O = glutathione + H(+) + succinate."^^xsd:string) AnnotationAssertion(rdfs:label "S-succinylglutathione hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "salicyl-alcohol b-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.172"^^xsd:string) Annotation( "RHEA:11515"^^xsd:string) "Catalysis of the reaction: salicyl alcohol + UDP-D-glucose = H(+) + salicin + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.172"^^xsd:string) "UDPglucose:salicyl alcohol phenyl-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.172"^^xsd:string) "uridine diphosphoglucose-salicyl alcohol 2-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.172"^^xsd:string) "UDP-glucose:salicyl-alcohol beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "salicyl-alcohol glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.172"^^xsd:string) "UDPglucose:salicyl-alcohol beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "salicyl-alcohol beta-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.128"^^xsd:string) Annotation( "RHEA:20456"^^xsd:string) "Catalysis of the reaction: scopoletin + UDP-D-glucose = H(+) + scopolin + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.128"^^xsd:string) "SGTase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.128"^^xsd:string) "uridine diphosphoglucose-scopoletin glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.128"^^xsd:string) "UDPglucose:scopoletin O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.128"^^xsd:string) "UDPglucose:scopoletin glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.128"^^xsd:string) "UDP-glucose:scopoletin O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "scopoletin glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.65"^^xsd:string) "scyllo-inosamine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.65"^^xsd:string) "ATP:1-amino-1-deoxy-scyllo-inositol 4-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.65"^^xsd:string) Annotation( "RHEA:18608"^^xsd:string) "Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol + ATP = 1-amino-1-deoxy-scyllo-inositol 4-phosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.65"^^xsd:string) "ATP:inosamine phosphotransferase activity"^^xsd:string) AnnotationAssertion( "scyllo-inosamine kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "scyllo-inosamine 4-kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.14"^^xsd:string) Annotation( "RHEA:23847"^^xsd:string) "Catalysis of the reaction: ATP + sedoheptulose = ADP + 2 H(+) + sedoheptulose 7-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.14"^^xsd:string) "heptulokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.14"^^xsd:string) "ATP:sedoheptulose 7-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.14"^^xsd:string) "sedoheptulokinase (phosphorylating)"^^xsd:string) AnnotationAssertion(rdfs:label "sedoheptulokinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.37"^^xsd:string) "sedoheptulose bisphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.37"^^xsd:string) Annotation( "MetaCyc:SEDOHEPTULOSE-BISPHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.37"^^xsd:string) "SBPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.37"^^xsd:string) "sedoheptulose-1,7-bisphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.37"^^xsd:string) "sedoheptulose 1,7-diphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.37"^^xsd:string) "sedoheptulose 1,7-diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.37"^^xsd:string) "sedoheptulose-1,7-bisphosphate 1-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.37"^^xsd:string) "sedoheptulose diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.37"^^xsd:string) "sedoheptulose 1,7-bisphosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sedoheptulose-bisphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.4.24"^^xsd:string) "sepiapterin aminohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sepiapterin deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.4.24"^^xsd:string) Annotation( "MetaCyc:SEPIAPTERIN-DEAMINASE-RXN"^^xsd:string) "Catalysis of the reaction: sepiapterin + H2O = xanthopterin-B2 + NH3."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sequoyitol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.143"^^xsd:string) Annotation( "RHEA:11303"^^xsd:string) "Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + NAD(+) = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.143"^^xsd:string) "5-O-methyl-myo-inositol:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.45"^^xsd:string) "L-serine:glyoxylate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.45"^^xsd:string) "SGAT activity"^^xsd:string) AnnotationAssertion(rdfs:label "serine-glyoxylate transaminase activity"^^xsd:string) AnnotationAssertion( "serine--glyoxylate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.45"^^xsd:string) Annotation( "MetaCyc:SERINE--GLYOXYLATE-AMINOTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: L-serine + glyoxylate = 3-hydroxypyruvate + glycine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.1.7"^^xsd:string) Annotation( "MetaCyc:SERINE-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: L-serine + H2O + NAD+ = 3-hydroxypyruvate + NH3 + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.7"^^xsd:string) "L-serine:NAD oxidoreductase (deaminating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "serine 2-dehydrogenase activity"^^xsd:string) AnnotationAssertion( "serine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.7"^^xsd:string) "L-serine:NAD+ 2-oxidoreductase (deaminating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "serine-sulphate ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.10"^^xsd:string) "(L-SOS)lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "serine-sulfate ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.10"^^xsd:string) Annotation( "MetaCyc:SERINE-SULFATE-AMMONIA-LYASE-RXN"^^xsd:string) "Catalysis of the reaction: L-serine O-sulfate + H2O = pyruvate + NH3 + sulfate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.10"^^xsd:string) "L-serine-O-sulfate ammonia-lyase (pyruvate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.120"^^xsd:string) "UDPglucose:sinapate D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sinapate 1-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.120"^^xsd:string) "UDP-glucose:sinapate D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.120"^^xsd:string) "UDPglucose:sinapic acid glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.120"^^xsd:string) Annotation( "MetaCyc:SINAPATE-1-GLUCOSYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: UDP-glucose + sinapate = UDP + 1-sinapoyl-D-glucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.120"^^xsd:string) "uridine diphosphoglucose-sinapate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.120"^^xsd:string) "uridine 5'-diphosphoglucose-hydroxycinnamic acid acylglucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sinapine esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.49"^^xsd:string) Annotation( "RHEA:10019"^^xsd:string) "Catalysis of the reaction: O-sinapoylcholine + H(2)O = choline + H(+) + sinapate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.49"^^xsd:string) "aromatic choline esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.49"^^xsd:string) "sinapoylcholine sinapohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.50"^^xsd:string) Annotation( "RHEA:24583"^^xsd:string) "Catalysis of the reaction: D-glucitol 6-phosphate + H(2)O = D-glucitol + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "sorbitol-6-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.50"^^xsd:string) "sorbitol-6-phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.50"^^xsd:string) "sorbitol-6-phosphate phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.123"^^xsd:string) "sorbose (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sorbose 5-dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.123"^^xsd:string) Annotation( "RHEA:15004"^^xsd:string) "Catalysis of the reaction: L-sorbose + NADP(+) = 5-dehydro-D-fructose + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.123"^^xsd:string) "5-keto-D-fructose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.123"^^xsd:string) "reduced nicotinamide adenine dinucleotide phosphate-linked reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.123"^^xsd:string) "5-ketofructose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.123"^^xsd:string) "L-sorbose:NADP+ 5-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.12"^^xsd:string) "L-sorbose:(acceptor) 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.12"^^xsd:string) "L-sorbose:acceptor 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.99.12"^^xsd:string) Annotation( "RHEA:14716"^^xsd:string) "Catalysis of the reaction: L-sorbose + A = 5-dehydro-D-fructose + AH(2)."^^xsd:string) AnnotationAssertion(rdfs:label "sorbose dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.99.6"^^xsd:string) "spermidine:(acceptor) oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "spermidine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.6"^^xsd:string) Annotation( "MetaCyc:SPERMIDINE-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: spermidine + acceptor + H2O = 1,3-diaminopropane + 4-aminobutanal + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.99.6"^^xsd:string) "spermidine:acceptor oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.41"^^xsd:string) "sphingomyelinase D"^^xsd:string) AnnotationAssertion(rdfs:label "sphingomyelin phosphodiesterase D activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.41"^^xsd:string) "sphingomyelin ceramide-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.41"^^xsd:string) Annotation( "RHEA:20987"^^xsd:string) "Catalysis of the reaction: H(2)O + sphingomyelin = ceramide 1-phosphate + choline + H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.24"^^xsd:string) Annotation( "MetaCyc:SPHINGOSINE-N-ACYLTRANSFERASE-RXN"^^xsd:string) Annotation( "PMID:12069845"^^xsd:string) "Catalysis of the reaction: acyl-CoA + sphingosine = CoA + N-acylsphingosine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.24"^^xsd:string) "acyl-CoA:sphingosine N-acyltransferase activity"^^xsd:string) AnnotationAssertion( "dihydroceramide synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sphingosine N-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.24"^^xsd:string) "sphingosine acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.24"^^xsd:string) "ceramide synthetase activity"^^xsd:string) AnnotationAssertion( "ceramide synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.24"^^xsd:string) "steroid 9alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.24"^^xsd:string) Annotation( "RHEA:19560"^^xsd:string) "Catalysis of the reaction: AH(2) + O(2) + pregna-4,9(11)-diene-3,20-dione = 9,11alpha-epoxypregn-4-ene-3,20-dione + A + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.24"^^xsd:string) "steroid 9-alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion( "steroid 9a-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.24"^^xsd:string) "steroid,hydrogen-donor:oxygen oxidoreductase (9-epoxidizing)"^^xsd:string) AnnotationAssertion(rdfs:label "steroid 9-alpha-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.24"^^xsd:string) "steroid 9alpha-monooxygenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "steroid-lactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.37"^^xsd:string) Annotation( "RHEA:13724"^^xsd:string) "Catalysis of the reaction: H(2)O + testololactone = H(+) + testolate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.37"^^xsd:string) "testololactone lactonohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.15"^^xsd:string) "3'-phosphoadenylyl-sulfate:phenolic-steroid sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.15"^^xsd:string) "steroid alcohol sulfotransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.15"^^xsd:string) Annotation( "MetaCyc:STEROID-SULFOTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate."^^xsd:string) AnnotationAssertion( "steroid sulphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "steroid sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.104"^^xsd:string) Annotation( "RHEA:11959"^^xsd:string) "Catalysis of the reaction: cholesteryl-beta-D-glucoside + H(2)O = D-glucose + cholesterol."^^xsd:string) AnnotationAssertion( "steryl-b-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.104"^^xsd:string) "cholesteryl-beta-D-glucoside glucohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "steryl-beta-glucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.60"^^xsd:string) Annotation( "RHEA:13888"^^xsd:string) "Catalysis of the reaction: H(2)O + stipitatonate = CO(2) + H(+) + stipitatate."^^xsd:string) AnnotationAssertion(rdfs:label "stipitatonate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.60"^^xsd:string) "stipitatonate carboxy-lyase (decyclizing, stipitatate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.60"^^xsd:string) "stipitatonate carboxy-lyase (decyclizing)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "stizolobate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.29"^^xsd:string) "3,4-dihydroxy-L-phenylalanine:oxygen 4,5-oxidoreductase (recyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.29"^^xsd:string) Annotation( "MetaCyc:STIZOLOBATE-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.30"^^xsd:string) "3,4-dihydroxy-L-phenylalanine:oxygen 2,3-oxidoreductase (recyclizing)"^^xsd:string) AnnotationAssertion(rdfs:label "stizolobinate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.30"^^xsd:string) Annotation( "MetaCyc:STIZOLOBINATE-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.87"^^xsd:string) "streptomycin 3''-kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.87"^^xsd:string) "ATP:streptomycin 3''-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.87"^^xsd:string) "streptomycin 3''-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.87"^^xsd:string) Annotation( "RHEA:18380"^^xsd:string) "Catalysis of the reaction: ATP + streptomycin = ADP + 2 H(+) + streptomycin 3''-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "streptomycin 3''-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.72"^^xsd:string) "ATP:streptomycin 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion( "streptomycin 6-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.72"^^xsd:string) "streptomycin 6-kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.72"^^xsd:string) "streptomycin 6-O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.72"^^xsd:string) Annotation( "RHEA:22271"^^xsd:string) "Catalysis of the reaction: ATP + streptomycin = ADP + 2 H(+) + streptomycin 6-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.72"^^xsd:string) "streptomycin 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aminoglycoside 6-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.72"^^xsd:string) "streptidine kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.72"^^xsd:string) "APH(6) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.72"^^xsd:string) "streptidine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.72"^^xsd:string) "SM 6-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.39"^^xsd:string) "streptomycin 6-phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.39"^^xsd:string) Annotation( "RHEA:10691"^^xsd:string) "Catalysis of the reaction: H(2)O + streptomycin 6-phosphate = phosphate + streptomycin."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.39"^^xsd:string) "streptomycin-6-P phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.39"^^xsd:string) "streptomycin 6-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "streptomycin-6-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.39"^^xsd:string) "streptomycin-6-phosphate phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.3.7"^^xsd:string) "indole-3-acetaldehyde:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.7"^^xsd:string) "indoleacetaldehyde oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.7"^^xsd:string) "IAA oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "indole-3-acetaldehyde oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.7"^^xsd:string) Annotation( "RHEA:16280"^^xsd:string) "Catalysis of the reaction: (indol-3-yl)acetaldehyde + H(2)O + O(2) = (indol-3-yl)acetate + H(2)O(2) + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.7"^^xsd:string) "IAAld oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.7"^^xsd:string) "AO1"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.3.7"^^xsd:string) "(indol-3-yl)acetaldehyde:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lysine 6-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.18"^^xsd:string) "LysDH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.18"^^xsd:string) "L-lysine 6-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.18"^^xsd:string) Annotation( "MetaCyc:LYSINE-6-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: H2O + NAD+ + L-lysine = NH3 + NADH + allysine."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.18"^^xsd:string) "L-lysine:NAD+ 6-oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.18"^^xsd:string) "L-lysine epsilon-dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.2.4"^^xsd:string) "nitrogen:(acceptor) oxidoreductase (N2O-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.4"^^xsd:string) "N2O reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.4"^^xsd:string) "nitrogen:acceptor oxidoreductase (N2O-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "nitrous-oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.4"^^xsd:string) "nitrous oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.4"^^xsd:string) Annotation( "MetaCyc:RXN-12130"^^xsd:string) "Catalysis of the reaction: H(2)O + 2 cytochrome c + nitrogen = 2 reduced cytochrome c + nitrous oxide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.22"^^xsd:string) "N-(carboxymethyl)-D-alanine:NAD+ oxidoreductase (glycine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.22"^^xsd:string) Annotation( "RHEA:14064"^^xsd:string) "Catalysis of the reaction: N-(carboxymethyl)-D-alanine + H(2)O + NAD(+) = glycine + H(+) + NADH + pyruvate."^^xsd:string) AnnotationAssertion(rdfs:label "strombine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.22"^^xsd:string) "N-(carboxymethyl)-D-alanine: NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.22"^^xsd:string) "strombine[N-(carboxymethyl)-D-alanine]dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.99"^^xsd:string) "sucrose 1(F)-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.99"^^xsd:string) "SST activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.99"^^xsd:string) "sucrose:sucrose fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.99"^^xsd:string) "sucrose:sucrose 1F-beta-D-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.99"^^xsd:string) "sucrose:sucrose 1(F)-beta-D-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.99"^^xsd:string) "sucrose:sucrose 1'-beta-D-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.99"^^xsd:string) Annotation( "MetaCyc:SUCROSE-1F-FRUCTOSYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: 2 sucrose = D-glucose + 1F-beta-D-fructosylsucrose."^^xsd:string) AnnotationAssertion(rdfs:label "sucrose 1F-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.99"^^xsd:string) "sucrose-sucrose 1-fructosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.99"^^xsd:string) "sucrose:sucrose 1-fructosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.24"^^xsd:string) "sucrose 6-phosphate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.24"^^xsd:string) Annotation( "MetaCyc:SUCROSE-PHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: sucrose 6F-phosphate + H2O = sucrose + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.24"^^xsd:string) Annotation( ) "sucrose-6F-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.24"^^xsd:string) "sucrose-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sucrose-phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.24"^^xsd:string) "sucrose-phosphate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sugar-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.23"^^xsd:string) Annotation( ) "sugar-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.23"^^xsd:string) Annotation( "MetaCyc:SUGAR-PHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: sugar phosphate + H2O = sugar + phosphate."^^xsd:string) AnnotationAssertion( "sugar-phosphate phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sugar-terminal-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.58"^^xsd:string) Annotation( "MetaCyc:SUGAR-TERMINAL-PHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: H2O + sugar phosphorylated on the terminal carbon = a sugar + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.58"^^xsd:string) "xylitol-5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.58"^^xsd:string) Annotation( ) "sugar-omega-phosphate phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sulfite dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.2.1"^^xsd:string) Annotation( "MetaCyc:SULFITE-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: sulfite + 2 ferricytochrome c + H2O = sulfate + 2 ferrocytochrome c."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.2.1"^^xsd:string) "sulfite cytochrome c reductase activity"^^xsd:string) AnnotationAssertion( "sulphite dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.2.1"^^xsd:string) "sulfite-cytochrome c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.2.1"^^xsd:string) "sulfite:ferricytochrome-c oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.7.1"^^xsd:string) "hydrogen-sulfide:ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfite reductase (ferredoxin) activity"^^xsd:string) AnnotationAssertion( "sulphite reductase (ferredoxin) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.7.1"^^xsd:string) Annotation( "MetaCyc:SULFITE-REDUCTASE-FERREDOXIN-RXN"^^xsd:string) "Catalysis of the reaction: hydrogen sulfide + 3 oxidized ferredoxin + 3 H2O = sulfite + 3 reduced ferredoxin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.7.1"^^xsd:string) "ferredoxin-sulfite reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.12"^^xsd:string) Annotation( "MetaCyc:SULFOACETALDEHYDE-LYASE-RXN"^^xsd:string) "Catalysis of the reaction: 2-sulfoacetaldehyde + H2O = acetate + sulfite."^^xsd:string) AnnotationAssertion( "sulphoacetaldehyde lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfoacetaldehyde lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sulphur dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.18"^^xsd:string) "sulfur:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.18"^^xsd:string) Annotation( "MetaCyc:SULFUR-DIOXYGENASE-RXN"^^xsd:string) "Catalysis of the reaction: sulfur + O2 + H2O = sulfite."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.18"^^xsd:string) "S-sulfanylglutathione:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.18"^^xsd:string) "sulfur oxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfur dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sym-norspermidine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.23"^^xsd:string) "S-adenosylmethioninamine:propane-1,3-diamine 3-aminopropyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.23"^^xsd:string) Annotation( "RHEA:23247"^^xsd:string) "Catalysis of the reaction: 1,3-diaminopropane + S-adenosylmethioninamine = S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.88"^^xsd:string) Annotation( "RHEA:17516"^^xsd:string) "Catalysis of the reaction: synephrine = (4-hydroxyphenyl)acetaldehyde + methylammonium."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.88"^^xsd:string) "1-(4-hydroxyphenyl)-2-(methylamino)ethanol hydro-lyase (methylamine-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "synephrine dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.4.12"^^xsd:string) Annotation( "MetaCyc:T2-INDUCED-DEOXYNUCLEOTIDE-KINASE-RXN"^^xsd:string) "Catalysis of the reactions: ATP + dGMP = ADP + dGDP, and ATP + dTMP = ADP + dTDP."^^xsd:string) AnnotationAssertion(rdfs:label "T2-induced deoxynucleotide kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.12"^^xsd:string) "ATP:(d)NMP phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.101"^^xsd:string) "tagatose 6-phosphate kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.101"^^xsd:string) Annotation( "RHEA:15516"^^xsd:string) "Catalysis of the reaction: D-tagatose + ATP = D-tagatose 6-phosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.101"^^xsd:string) "ATP:D-tagatose 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.101"^^xsd:string) "D-tagatose 6-phosphate kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tagatose kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.20"^^xsd:string) "tannase S"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.20"^^xsd:string) "tannin acylhydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tannase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.20"^^xsd:string) Annotation( "RHEA:16368"^^xsd:string) "Catalysis of the reaction: digallate + H(2)O = 2 gallate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.20"^^xsd:string) "tannin acetylhydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.73"^^xsd:string) "(R,R)-tartrate carboxy-lyase (D-glycerate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "tartrate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.73"^^xsd:string) "(R,R)-tartrate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.73"^^xsd:string) Annotation( "RHEA:13320"^^xsd:string) "Catalysis of the reaction: L-tartrate + H(+) = D-glycerate + CO(2)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tartrate epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.2.5"^^xsd:string) Annotation( "RHEA:22215"^^xsd:string) "Catalysis of the reaction: L-tartrate = (2R,3S)-tartrate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.2.5"^^xsd:string) "tartaric racemase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.26"^^xsd:string) Annotation( "MetaCyc:TAU-PROTEIN-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.26"^^xsd:string) "TTK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.26"^^xsd:string) "glycogen synthase kinase-3beta activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.26"^^xsd:string) "cdk5/p20"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.26"^^xsd:string) "TPK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.26"^^xsd:string) "tau-protein kinase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.26"^^xsd:string) "tau-protein kinase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.26"^^xsd:string) "tau protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.26"^^xsd:string) "ATP:tau-protein O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.26"^^xsd:string) "CDK5/p23"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.26"^^xsd:string) "tau kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tau-protein kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.26"^^xsd:string) "tau-tubulin kinase activity"^^xsd:string) AnnotationAssertion( "[Tau protein] kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.26"^^xsd:string) "STK31"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.26"^^xsd:string) "TPK II"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.26"^^xsd:string) "brain protein kinase PK40erk activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.26"^^xsd:string) "protein tau kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.26"^^xsd:string) "TPK I"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.26"^^xsd:string) "GSK"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.55"^^xsd:string) Annotation( "MetaCyc:RXN-2301"^^xsd:string) "Catalysis of the reaction: taurine + 2-oxoglutarate = sulfoacetaldehyde + L-glutamate."^^xsd:string) AnnotationAssertion( "taurine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.55"^^xsd:string) "taurine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "taurine-2-oxoglutarate transaminase activity"^^xsd:string) AnnotationAssertion( "taurine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.55"^^xsd:string) "taurine--alpha-ketoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.55"^^xsd:string) "taurine--glutamate transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.99.2"^^xsd:string) "taurine:acceptor oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.99.2"^^xsd:string) Annotation( "RHEA:18712"^^xsd:string) "Catalysis of the reaction: A + H(2)O + taurine = AH(2) + NH(4)(+) + sulfoacetaldehyde."^^xsd:string) AnnotationAssertion(rdfs:label "taurine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.99.2"^^xsd:string) "taurine:(acceptor) oxidoreductase (deaminating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "taurocyamine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.4"^^xsd:string) Annotation( "RHEA:22519"^^xsd:string) "Catalysis of the reaction: ATP + taurocyamine = N-phosphotaurocyamine + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.4"^^xsd:string) "ATP:taurocyamine N-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.4"^^xsd:string) "ATP:taurocyamine phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.3.4"^^xsd:string) "taurocyamine phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tauropine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.23"^^xsd:string) "N2-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.23"^^xsd:string) "2-N-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.23"^^xsd:string) Annotation( "RHEA:12583"^^xsd:string) "Catalysis of the reaction: H(2)O + NAD(+) + tauropine = H(+) + NADH + pyruvate + taurine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.19"^^xsd:string) Annotation( "MetaCyc:TAXIFOLIN-8-MONOOXYGENASE-RXN"^^xsd:string) "Catalysis of the reaction: taxifolin + NAD(P)H + H+ + O2 = 2,3-dihydrogossypetin + NAD(P)+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "taxifolin 8-monooxygenase activity"^^xsd:string) AnnotationAssertion( "taxifolin hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.19"^^xsd:string) "taxifolin,NAD(P)H:oxygen oxidoreductase (8-hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.3.8"^^xsd:string) "(S)-tetrahydroberberine:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tetrahydroberberine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.8"^^xsd:string) Annotation( "MetaCyc:TETRAHYDROBERBERINE-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: (S)-tetrahydroberberine + 2 O2 = berberine + 2 H2O2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.8"^^xsd:string) "THB oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.8"^^xsd:string) "(S)-THB oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.5.1.3"^^xsd:string) "tetrahydroxypteridine lyase (isomerizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.3"^^xsd:string) Annotation( "RHEA:18100"^^xsd:string) "Catalysis of the reaction: tetrahydroxypteridine = H(+) + xanthine-8-carboxylate."^^xsd:string) AnnotationAssertion(rdfs:label "tetrahydroxypteridine cycloisomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.65"^^xsd:string) "5-N-ethyl-L-glutamine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.65"^^xsd:string) "N5-ethyl-L-glutamine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.65"^^xsd:string) "L-theanine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.65"^^xsd:string) Annotation( "RHEA:18016"^^xsd:string) "Catalysis of the reaction: N(5)-ethyl-L-glutamine + H(2)O = L-glutamate + ethylamine."^^xsd:string) AnnotationAssertion(rdfs:label "theanine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "thiamin diphosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.15"^^xsd:string) "TDP kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiamine-diphosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.15"^^xsd:string) "protein bound thiamin diphosphate:ATP phosphoryltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.15"^^xsd:string) Annotation( "MetaCyc:THIAMIN-DIPHOSPHATE-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + thiamin diphosphate = ADP + thiamin triphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.15"^^xsd:string) "ATP:thiamine-diphosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.15"^^xsd:string) "ATP:thiamin-diphosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.15"^^xsd:string) "thiamin diphosphate phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.15"^^xsd:string) "thiamin pyrophosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.4.15"^^xsd:string) "thiamine diphosphate kinase activity"^^xsd:string) AnnotationAssertion( "thiamin-diphosphate kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.2"^^xsd:string) "thiamin pyridinolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.2"^^xsd:string) "pyrimidine transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.2"^^xsd:string) "thiamine pyridinolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiamine pyridinylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.2"^^xsd:string) "thiamine hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.2"^^xsd:string) "thiamin hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "thiamin pyridinylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.2"^^xsd:string) "thiaminase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.2"^^xsd:string) "thiamine:base 2-methyl-4-aminopyrimidine-5-methenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.2"^^xsd:string) "thiamin:base 2-methyl-4-aminopyrimidine-5-methenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.2"^^xsd:string) Annotation( "RHEA:17700"^^xsd:string) "Catalysis of the reaction: pyridine + thiamine = 5-(2-hydroxyethyl)-4-methylthiazole + heteropyrithiamine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thiamin-triphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.28"^^xsd:string) "thiamine-triphosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.28"^^xsd:string) "ThTPase activity"^^xsd:string) AnnotationAssertion( "thiamine-triphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.28"^^xsd:string) Annotation( "RHEA:11747"^^xsd:string) "Catalysis of the reaction: H(2)O + thiamine triphosphate = H(+) + phosphate + thiamine diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.99.2"^^xsd:string) Annotation( "RHEA:17512"^^xsd:string) "Catalysis of the reaction: H(2)O + thiamine = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "thiaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.2"^^xsd:string) "thiaminase II activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.99.1.1"^^xsd:string) "isothiocyanate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.99.1.1"^^xsd:string) "benzyl-thiocyanate isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiocyanate isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.99.1.1"^^xsd:string) Annotation( "RHEA:10007"^^xsd:string) "Catalysis of the reaction: benzyl isothiocyanate = benzyl thiocyanate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.11"^^xsd:string) "acetyl-CoA:thioethanolamine S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.11"^^xsd:string) "acetyl-CoA:2-aminoethanethiol S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thioethanolamine S-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.11"^^xsd:string) "thioltransacetylase B activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.11"^^xsd:string) "thioethanolamine acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.11"^^xsd:string) Annotation( "RHEA:23283"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + cysteamine = S-acetylcysteamine + CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.1.3"^^xsd:string) Annotation( "MetaCyc:THIOSULFATE--THIOL-SULFURTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: thiosulfate + 2 glutathione = sulfite + glutathione disulfide + sulfide."^^xsd:string) AnnotationAssertion(rdfs:label "thiosulfate-thiol sulfurtransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.3"^^xsd:string) "sulfane sulfurtransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.3"^^xsd:string) "thiosulfate:thiol sulfurtransferase activity"^^xsd:string) AnnotationAssertion( "thiosulphate-thiol sulphurtransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.3"^^xsd:string) "sulfane reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.3"^^xsd:string) "glutathione-dependent thiosulfate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.2.2"^^xsd:string) "thiosulfate:ferricytochrome-c oxidoreductase activity"^^xsd:string) AnnotationAssertion( "thiosulphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.2.2"^^xsd:string) "thiosulfate-acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.2.2"^^xsd:string) "tetrathionate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.2.2"^^xsd:string) "thiosulfate-oxidizing enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.2.2"^^xsd:string) Annotation( "MetaCyc:THIOSULFATE-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: 2 thiosulfate + 2 ferricytochrome c = tetrathionate + 2 ferrocytochrome c."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.2.2"^^xsd:string) "thiosulfate oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiosulfate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.39"^^xsd:string) Annotation( "MetaCyc:THYMIDINE-TRIPHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: dTTP + H2O = dTDP + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.39"^^xsd:string) "dTTP nucleotidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.39"^^xsd:string) "thymidine triphosphate nucleotidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thymidine-triphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.39"^^xsd:string) "dTTPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.39"^^xsd:string) "deoxythymidine-5'-triphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.35"^^xsd:string) "deoxythymidylate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thymidylate 5'-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.35"^^xsd:string) "thymidylate nucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.35"^^xsd:string) "thymidylate 5'-nucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.35"^^xsd:string) Annotation( "MetaCyc:THYMIDYLATE-5-PHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: thymidylate + H2O = thymidine + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.35"^^xsd:string) "deoxythymidylate 5'-nucleotidase activity"^^xsd:string) AnnotationAssertion( "thymidylate 5' phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.35"^^xsd:string) "dTMPase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.35"^^xsd:string) "thymidylate 5'-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.35"^^xsd:string) "deoxythymidylic 5'-nucleotidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.6"^^xsd:string) "thymine 7-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.6"^^xsd:string) "thymine,2-oxoglutarate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.6"^^xsd:string) "5-hydroxymethyluracil oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.6"^^xsd:string) "5-hydroxy-methyluracil dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thymine dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.6"^^xsd:string) "thymine,2-oxoglutarate:oxygen oxidoreductase (7-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.6"^^xsd:string) Annotation( "MetaCyc:THYMINE-DIOXYGENASE-RXN"^^xsd:string) "Catalysis of the reaction: thymine + 2-oxoglutarate + O2 = 5-hydroxymethyluracil + succinate + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.95"^^xsd:string) Annotation( "MetaCyc:TOCOPHEROL-O-METHYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + gamma-tocopherol = S-adenosyl-L-homocysteine + alpha-tocopherol."^^xsd:string) AnnotationAssertion( "gamma-tocopherol methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tocopherol O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.95"^^xsd:string) "S-adenosyl-L-methionine:gamma-tocopherol 5-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.44"^^xsd:string) "acyl-CoA:NAD+ trans-2-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.44"^^xsd:string) Annotation( "MetaCyc:TRANS-2-ENOYL-COA-REDUCTASE-NAD+-RXN"^^xsd:string) "Catalysis of the reaction: acyl-CoA + NAD+ = trans-didehydroacyl-CoA + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "trans-2-enoyl-CoA reductase (NAD+) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.14"^^xsd:string) "cinnamic 2-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trans-cinnamate 2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.14"^^xsd:string) "cinnamate 2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.14"^^xsd:string) "cinnamate 2-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.14"^^xsd:string) "cinnamic acid 2-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.14"^^xsd:string) Annotation( "RHEA:10959"^^xsd:string) "Catalysis of the reaction: trans-cinnamate + H(+) + NADPH + O(2) = 2-coumarate + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.14"^^xsd:string) "trans-cinnamate,NADPH:oxygen oxidoreductase (2-hydroxylating)"^^xsd:string) AnnotationAssertion( "trans-cinnamic acid 2-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.3.2.4"^^xsd:string) Annotation( "RHEA:20743"^^xsd:string) "Catalysis of the reaction: trans-2,3-epoxysuccinate + H(2)O = (2R,3S)-tartrate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.4"^^xsd:string) "tartrate epoxydase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.4"^^xsd:string) "trans-2,3-epoxysuccinate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.3.2.4"^^xsd:string) "trans-epoxysuccinate hydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trans-epoxysuccinate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.77"^^xsd:string) Annotation( "RHEA:10323"^^xsd:string) "Catalysis of the reaction: trans-L-3-hydroxyproline = 1-pyrroline-2-carboxylate + H(2)O + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "trans-L-3-hydroxyproline dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.77"^^xsd:string) "trans-L-3-hydroxyproline hydro-lyase (Delta1-pyrroline 2-carboxylate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.77"^^xsd:string) "trans-L-3-hydroxyproline hydro-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.11"^^xsd:string) "nonaprenyl pyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.11"^^xsd:string) "solanesyl pyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:11327"^^xsd:string) "Catalysis of the reaction: all-trans-octaprenyl diphosphate + isopentenyl diphosphate = all-trans-nonaprenyl diphosphate + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.11"^^xsd:string) "trans-prenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.11"^^xsd:string) "terpenoidallyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.11"^^xsd:string) "terpenyl pyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.11"^^xsd:string) "polyprenylpyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.11"^^xsd:string) "(E)-octaprenyl-diphosphate:isopentenyl-diphosphate octaprenyltranstransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.11"^^xsd:string) "all-trans-nonaprenyl-diphosphate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trans-octaprenyltranstransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.11"^^xsd:string) "SPP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.11"^^xsd:string) "solanesyl-diphosphate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.122"^^xsd:string) "alpha,alpha'-trehalose-6-mycolate:alpha,alpha'-trehalose-6-mycolate 6'-mycolyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.122"^^xsd:string) "alpha,alpha'-trehalose 6-monomycolate:alpha,alpha'-trehalose mycolyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.122"^^xsd:string) Annotation( "RHEA:23475"^^xsd:string) "Catalysis of the reaction: 2 alpha,alpha'-trehalose 6-mycolate = alpha,alpha'-trehalose 6,6'-bismycolate + alpha,alpha-trehalose."^^xsd:string) AnnotationAssertion(rdfs:label "trehalose O-mycolyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.38"^^xsd:string) "TAL hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.38"^^xsd:string) "triacetic acid lactone hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.38"^^xsd:string) "triacetolactone lactonohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.38"^^xsd:string) "triacetate lactone hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.38"^^xsd:string) "triacetic lactone hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.38"^^xsd:string) Annotation( "RHEA:22263"^^xsd:string) "Catalysis of the reaction: H(2)O + triacetate lactone = triacetate."^^xsd:string) AnnotationAssertion(rdfs:label "triacetate-lactonase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.95"^^xsd:string) Annotation( "MetaCyc:TRIHYDROXYSTILBENE-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + 3,4',5-trihydroxy-stilbene + 4 CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.95"^^xsd:string) "resveratrol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.95"^^xsd:string) "stilbene synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trihydroxystilbene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.95"^^xsd:string) "malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.2"^^xsd:string) Annotation( "RHEA:11091"^^xsd:string) "Catalysis of the reaction: H(2)O + trimetaphosphate = 2 H(+) + triphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.2"^^xsd:string) "inorganic trimetaphosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trimetaphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.2"^^xsd:string) "trimetaphosphate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.32"^^xsd:string) "trimethylamine-N-oxide formaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trimethylamine-oxide aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.32"^^xsd:string) "trimethylamine N-oxide aldolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.32"^^xsd:string) Annotation( "RHEA:20220"^^xsd:string) "Catalysis of the reaction: H(+) + trimethylamine N-oxide = dimethylamine + formaldehyde."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.32"^^xsd:string) "trimethylamine N-oxide demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.32"^^xsd:string) "trimethylamine-N-oxide formaldehyde-lyase (dimethylamine-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.32"^^xsd:string) "trimethylamine N-oxide formaldehyde-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.8"^^xsd:string) "trimethyllysine alpha-ketoglutarate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.8"^^xsd:string) "TML-alpha-ketoglutarate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.8"^^xsd:string) "trimethyllysine,2-oxoglutarate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.8"^^xsd:string) "N6,N6,N6-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "trimethyllysine dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.8"^^xsd:string) "epsilon-trimethyllysine 2-oxoglutarate dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.8"^^xsd:string) Annotation( "RHEA:14184"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O(2) = 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO(2) + succinate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.8"^^xsd:string) "TML hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.8"^^xsd:string) "TMLD activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.8"^^xsd:string) "TML dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.8"^^xsd:string) "6-N,6-N,6-N-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.28"^^xsd:string) "ATP:D-glyceraldehyde 3-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "triokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.28"^^xsd:string) "D-triokinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.28"^^xsd:string) "trio triose kinase (phosphorylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.28"^^xsd:string) "triose kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.28"^^xsd:string) Annotation( "RHEA:13944"^^xsd:string) "Catalysis of the reaction: D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + 2 H(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.25"^^xsd:string) Annotation( "RHEA:14160"^^xsd:string) "Catalysis of the reaction: H(2)O + triphosphate = diphosphate + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "triphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:24004165"^^xsd:string) "tripolyphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.25"^^xsd:string) "inorganic triphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.25"^^xsd:string) "triphosphate phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.206"^^xsd:string) "tropine:NADP+ 3alpha-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tropine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.206"^^xsd:string) Annotation( "RHEA:18360"^^xsd:string) "Catalysis of the reaction: NADP(+) + tropine = H(+) + NADPH + tropinone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.10"^^xsd:string) "tropine esterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tropinesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.10"^^xsd:string) "atropinesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.10"^^xsd:string) "atropinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.10"^^xsd:string) Annotation( "RHEA:23307"^^xsd:string) "Catalysis of the reaction: atropine + H(2)O = H(+) + tropate + tropine."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.10"^^xsd:string) "atropine acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.10"^^xsd:string) "atropine esterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.236"^^xsd:string) "pseudotropine:NADP+ 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.236"^^xsd:string) Annotation( "RHEA:24247"^^xsd:string) "Catalysis of the reaction: NADP(+) + pseudotropine = H(+) + NADPH + tropinone."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.236"^^xsd:string) "pseudotropine forming tropinone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.236"^^xsd:string) "tropinone (psi-tropine-forming) reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tropinone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.236"^^xsd:string) "tropinone reductase II activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.28"^^xsd:string) "ATP:tropomyosin O-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.28"^^xsd:string) Annotation( "MetaCyc:TROPOMYOSIN-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + tropomyosin = ADP + O-phosphotropomyosin."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.28"^^xsd:string) "tropomyosin kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.28"^^xsd:string) "STK"^^xsd:string) AnnotationAssertion(rdfs:label "tropomyosin kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.99.3"^^xsd:string) "tryptophan side chain oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.99.3"^^xsd:string) "TSO activity"^^xsd:string) AnnotationAssertion(rdfs:label "tryptophan 2'-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.99.3"^^xsd:string) "tryptophan side chain oxidase II"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.99.3"^^xsd:string) "TSO II"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.99.3"^^xsd:string) "indolyl-3-alkan alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.99.3"^^xsd:string) "TSO I"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.99.3"^^xsd:string) "tryptophan side-chain alpha,beta-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.99.3"^^xsd:string) "L-tryptophan:oxygen 2'-oxidoreductase (side-chain-cleaving)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.99.3"^^xsd:string) Annotation( "MetaCyc:TRYPTOPHAN-2-DIOXYGENASE-RXN"^^xsd:string) "Catalysis of the reaction: L-tryptophan + O2 = 3-indoleglycolaldehyde + CO2 + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.99.3"^^xsd:string) "tryptophan side-chain oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.99.3"^^xsd:string) "indole-3-alkane alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.99.3"^^xsd:string) "tryptophan side chain oxidase type I"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.12.3"^^xsd:string) "L-tryptophan:oxygen 2-oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.3"^^xsd:string) Annotation( "RHEA:16168"^^xsd:string) "Catalysis of the reaction: L-tryptophan + O(2) = CO(2) + H(2)O + indole-3-acetamide."^^xsd:string) AnnotationAssertion(rdfs:label "tryptophan 2-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.6.1.27"^^xsd:string) "L-tryptophan aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.27"^^xsd:string) "5-hydroxytryptophan-ketoglutaric transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.27"^^xsd:string) "tryptophan transaminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-tryptophan:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.27"^^xsd:string) "L-tryptophan transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.27"^^xsd:string) "L-phenylalanine-2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.27"^^xsd:string) "hydroxytryptophan aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.27"^^xsd:string) Annotation( "MetaCyc:TRYPTOPHAN-AMINOTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: L-tryptophan + 2-oxoglutarate = indolepyruvate + L-glutamate."^^xsd:string) AnnotationAssertion( "tryptophan aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tryptophan dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.19"^^xsd:string) "L-Trp-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.19"^^xsd:string) "TrpDH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.19"^^xsd:string) Annotation( "MetaCyc:TRYPTOPHAN-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: L-tryptophan + NAD(P)+ = (indol-3-yl)pyruvate + NH3 + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.19"^^xsd:string) "L-tryptophan dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.19"^^xsd:string) "NAD(P)+-L-tryptophan dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.19"^^xsd:string) "L-tryptophan:NAD(P)+ oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.19"^^xsd:string) "TDH"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.34"^^xsd:string) "dimethylallylpyrophosphate:tryptophan dimethylallyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.34"^^xsd:string) "4-(gamma,gamma-dimethylallyl)tryptophan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.34"^^xsd:string) "dimethylallyl-diphosphate:L-tryptophan dimethylallyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.34"^^xsd:string) "DMAT synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.34"^^xsd:string) Annotation( "MetaCyc:TRYPTOPHAN-DIMETHYLALLYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: dimethylallyl diphosphate + L-tryptophan = diphosphate + 4-(3-methylbut-2-enyl)-L-tryptophan."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.34"^^xsd:string) "dimethylallyltryptophan synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tryptophan dimethylallyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.34"^^xsd:string) "dimethylallylpyrophosphate:L-tryptophan dimethylallyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.57"^^xsd:string) Annotation( "RHEA:11015"^^xsd:string) "Catalysis of the reaction: L-tryptophanamide + H(2)O = L-tryptophan + NH(4)(+)."^^xsd:string) AnnotationAssertion(rdfs:label "tryptophanamidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.57"^^xsd:string) "tryptophan aminopeptidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.57"^^xsd:string) "L-tryptophanamide amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.57"^^xsd:string) "L-tryptophan aminopeptidase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.110"^^xsd:string) "feruloyltyramine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.110"^^xsd:string) Annotation( "MetaCyc:TYRAMINE-N-FERULOYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: feruloyl-CoA + tyramine = CoA + N-feruloyltyramine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.110"^^xsd:string) "tyramine feruloyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.110"^^xsd:string) "tyramine N-feruloyl-CoA transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.110"^^xsd:string) "feruloyl-CoA:tyramine N-(hydroxycinnamoyl)transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.110"^^xsd:string) "feruloyl-CoA tyramine N-feruloyl-CoA transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tyramine N-feruloyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.24"^^xsd:string) "kyotorphin-synthesizing enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "tyrosine-arginine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.24"^^xsd:string) "tyrosyl-arginine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.24"^^xsd:string) "kyotorphin synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.24"^^xsd:string) "kyotorphin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.24"^^xsd:string) "L-tyrosine:L-arginine ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.24"^^xsd:string) Annotation( "RHEA:15348"^^xsd:string) "Catalysis of the reaction: L-arginine + L-tyrosine + ATP = L-tyrosyl-L-arginine + AMP + diphosphate + 2 H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.3.6"^^xsd:string) Annotation( "RHEA:15784"^^xsd:string) "Catalysis of the reaction: L-tyrosine = 3-amino-3-(4-hydroxyphenyl)propanoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.3.6"^^xsd:string) "tyrosine alpha,beta-mutase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tyrosine 2,3-aminomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.3.6"^^xsd:string) "L-tyrosine 2,3-aminomutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.6"^^xsd:string) Annotation( "MetaCyc:TYROSINE-3-MONOOXYGENASE-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + [tyrosine-3-monooxygenase] = ADP + phospho-[tyrosine-3-monooxygenase]."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.6"^^xsd:string) "STK4"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.6"^^xsd:string) "tyrosine 3-monooxygenase kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "[tyrosine 3-monooxygenase] kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.6"^^xsd:string) "ATP:tyrosine-3-monoxygenase phosphotransferase activity"^^xsd:string) AnnotationAssertion( "tyrosine 3-monooxygenase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.6"^^xsd:string) "pheochromocytoma tyrosine hydroxylase-associated kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tyrosine N-monooxygenase activity"^^xsd:string) AnnotationAssertion( "tyrosine N-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.41"^^xsd:string) "CYP79A1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.41"^^xsd:string) Annotation( "MetaCyc:TYROSINE-N-MONOOXYGENASE-RXN"^^xsd:string) "Catalysis of the reaction: tyrosine + O2 + NADPH + H+ = N-hydroxytyrosine + NADP+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.41"^^xsd:string) "L-tyrosine,NADPH:oxygen oxidoreductase (N-hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.99.2"^^xsd:string) Annotation( "RHEA:21707"^^xsd:string) "Catalysis of the reaction: L-tyrosine + H(2)O = NH(4)(+) + phenol + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.2"^^xsd:string) "L-tyrosine phenol-lyase (deaminating)"^^xsd:string) AnnotationAssertion(rdfs:label "tyrosine phenol-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.2"^^xsd:string) "beta-tyrosinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.2"^^xsd:string) "L-tyrosine phenol-lyase (deaminating; pyruvate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ubiquitin-calmodulin ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.21"^^xsd:string) "ubiquityl-calmodulin synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.21"^^xsd:string) Annotation( "MetaCyc:UBIQUITIN--CALMODULIN-LIGASE-RXN"^^xsd:string) "Catalysis of the reaction: n ATP + calmodulin + n ubiquitin = n AMP + n diphosphate + ubiquitin(n)-calmodulin."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.21"^^xsd:string) "ubiquitin-calmodulin synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.21"^^xsd:string) "calmodulin:ubiquitin ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.21"^^xsd:string) "uCaM-synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.21"^^xsd:string) "ubiquityl-calmodulin synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.5"^^xsd:string) Annotation( "RHEA:11323"^^xsd:string) "Catalysis of the reaction: UDP-L-arabinose = UDP-alpha-D-xylose."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.5"^^xsd:string) "UDP-D-xylose 4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.5"^^xsd:string) "uridine 5'-diphosphate-D-xylose 4-epimerase activity"^^xsd:string) AnnotationAssertion( "UDP-D-xylose-4-epimerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-arabinose 4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.5"^^xsd:string) "UDP arabinose epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.5"^^xsd:string) "uridine diphosphoarabinose epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.5"^^xsd:string) "UDP-L-arabinose 4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.5"^^xsd:string) "UDParabinose 4-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.67"^^xsd:string) "UDP-D-galacturonate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-galacturonate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.67"^^xsd:string) Annotation( "RHEA:19728"^^xsd:string) "Catalysis of the reaction: H(+) + UDP-alpha-D-galacturonate = CO(2) + UDP-L-arabinose."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.67"^^xsd:string) "UDPgalacturonate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.67"^^xsd:string) "UDPGalUA carboxy lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.67"^^xsd:string) "UDP-galacturonic acid decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.67"^^xsd:string) "UDP-D-galacturonate carboxy-lyase (UDP-L-arabinose-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.16"^^xsd:string) "UDPglucosamine 4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.16"^^xsd:string) Annotation( "MetaCyc:UDP-GLUCOSAMINE-EPIMERASE-RXN"^^xsd:string) "Catalysis of the reaction: UDP-glucosamine = UDP-galactosamine."^^xsd:string) AnnotationAssertion(rdfs:label "UDP-glucosamine 4-epimerase activity"^^xsd:string) AnnotationAssertion( "UDP-glucosamine epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.76"^^xsd:string) Annotation( "RHEA:21503"^^xsd:string) "Catalysis of the reaction: UDP-D-glucose = H(2)O + UDP-4-dehydro-6-deoxy-D-glucose."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.76"^^xsd:string) "UDP-glucose 4,6-hydro-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-glucose 4,6-dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.76"^^xsd:string) "UDP-D-glucose-4,6-hydrolyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.76"^^xsd:string) "UDP-D-glucose oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.76"^^xsd:string) "UDPglucose 4,6-hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.76"^^xsd:string) "UDPglucose 4,6-dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.76"^^xsd:string) "UDP-glucose 4,6-hydro-lyase (UDP-4-dehydro-6-deoxy-D-glucose-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.1.3.6"^^xsd:string) "UDP-D-galacturonic acid 4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.6"^^xsd:string) "uridine diphospho-D-galacturonic acid"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.6"^^xsd:string) "uridine diphosphoglucuronic epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.6"^^xsd:string) "uridine diphosphoglucuronate epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.6"^^xsd:string) Annotation( "RHEA:11407"^^xsd:string) "Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-alpha-D-galacturonate."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.6"^^xsd:string) "UDP glucuronic epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.6"^^xsd:string) "UDP-galacturonate 4-epimerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-glucuronate 4-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.6"^^xsd:string) "UDPglucuronate 4-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UDP-glucuronate 5'-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.12"^^xsd:string) Annotation( "RHEA:14680"^^xsd:string) "Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-L-iduronate."^^xsd:string) AnnotationAssertion( "UDP-glucuronate 5' epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.12"^^xsd:string) "uridine diphosphoglucuronate 5'-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.12"^^xsd:string) "UDPglucuronate 5'-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.12"^^xsd:string) "UDP-glucuronic acid epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.12"^^xsd:string) "C-5-uronosyl epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.12"^^xsd:string) "UDP-glucuronic acid 5'-epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.6.1.27"^^xsd:string) "isoprenyl pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.27"^^xsd:string) "C(55)-isoprenyl pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.27"^^xsd:string) "undecaprenyl-diphosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.27"^^xsd:string) "C(55)-isoprenyl diphosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "undecaprenyl-diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.27"^^xsd:string) "C55-isoprenyl pyrophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.27"^^xsd:string) Annotation( "RHEA:17072"^^xsd:string) "Catalysis of the reaction: all-trans-undecaprenyl diphosphate + H(2)O = all-trans-undecaprenyl phosphate + H(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.6.1.27"^^xsd:string) "C55-isoprenyl diphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "uracil-5-carboxylate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.66"^^xsd:string) Annotation( "RHEA:17688"^^xsd:string) "Catalysis of the reaction: H(+) + uracil 5-carboxylate = CO(2) + uracil."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.66"^^xsd:string) "uracil-5-carboxylate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.66"^^xsd:string) "uracil-5-carboxylate carboxy-lyase (uracil-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.66"^^xsd:string) "uracil-5-carboxylic acid decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "uracil dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.99.4"^^xsd:string) Annotation( "MetaCyc:URACIL-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: uracil + acceptor = barbiturate + reduced acceptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "urate-ribonucleotide phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.16"^^xsd:string) Annotation( "RHEA:13912"^^xsd:string) "Catalysis of the reaction: 3-(beta-D-ribofuranosyl)uric acid + phosphate = alpha-D-ribose 1-phosphate + H(+) + urate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.16"^^xsd:string) "UAR phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.16"^^xsd:string) "urate-ribonucleotide:phosphate D-ribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.16"^^xsd:string) "urate-ribonucleotide:phosphate alpha-D-ribosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:24107613"^^xsd:string) "ureidoglycolate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.3"^^xsd:string) Annotation( "RHEA:11307"^^xsd:string) "Catalysis of the reaction: (S)-ureidoglycolate = glyoxylate + urea."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.3"^^xsd:string) "(S)-ureidoglycolate urea-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.3"^^xsd:string) "ureidoglycolatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.3"^^xsd:string) "ureidoglycolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ureidoglycolate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.3"^^xsd:string) "(S)-ureidoglycolate urea-lyase (glyoxylate-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ureidosuccinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.7"^^xsd:string) "N-carbamoyl-L-aspartate amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.7"^^xsd:string) Annotation( "RHEA:14368"^^xsd:string) "Catalysis of the reaction: N-carbamoyl-L-aspartate + H(2)O + 2 H(+) = L-aspartate + CO(2) + NH(4)(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.75"^^xsd:string) "urethane amidohydrolase (decarboxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "urethanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.75"^^xsd:string) "urethane hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.75"^^xsd:string) Annotation( "RHEA:21375"^^xsd:string) "Catalysis of the reaction: H(2)O + H(+) + urethane = CO(2) + ethanol + NH(4)(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.203"^^xsd:string) "uronate:NAD+ 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.203"^^xsd:string) "uronic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "uronate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.203"^^xsd:string) "uronate: NAD-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.203"^^xsd:string) Annotation( "RHEA:22407"^^xsd:string) "Catalysis of the reaction: D-galacturonate + H(2)O + NAD(+) = galactarate + 2 H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.19"^^xsd:string) Annotation( "MetaCyc:URONOLACTONASE-RXN"^^xsd:string) "Catalysis of the reaction: D-glucurono-6,2-lactone + H2O = D-glucuronate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.19"^^xsd:string) "D-glucurono-6,2-lactone lactonohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "uronolactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.19"^^xsd:string) "glucuronolactonase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.14"^^xsd:string) Annotation( "RHEA:18992"^^xsd:string) "Catalysis of the reaction: L-valine + H(+) = 2-methylpropanamine + CO(2)."^^xsd:string) AnnotationAssertion(rdfs:label "valine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.14"^^xsd:string) "L-valine carboxy-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.14"^^xsd:string) "leucine decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.14"^^xsd:string) "L-valine carboxy-lyase (2-methylpropanamine-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "valine dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.8"^^xsd:string) "L-valine:NADP+ oxidoreductase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.8"^^xsd:string) "valine dehydrogenase (nicotinanide adenine dinucleotide phosphate)"^^xsd:string) AnnotationAssertion(rdfs:label "valine dehydrogenase (NADP) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.1.8"^^xsd:string) Annotation( "MetaCyc:VALINE-DEHYDROGENASE-NADP+-RXN"^^xsd:string) "Catalysis of the reaction: L-valine + H2O + NADP+ = 3-methyl-2-oxobutanoate + NH3 + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.119"^^xsd:string) "vicianin hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "vicianin beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.119"^^xsd:string) Annotation( "RHEA:14044"^^xsd:string) "Catalysis of the reaction: (R)-vicianin + H(2)O = mandelonitrile + vicianose."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.119"^^xsd:string) "(R)-vicianin beta-D-glucohydrolase activity"^^xsd:string) AnnotationAssertion( "vicianin b-glucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "vinylacetyl-CoA D-isomerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "vinylacetyl-CoA delta-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.3"^^xsd:string) "vinylacetyl coenzyme A delta-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.3"^^xsd:string) Annotation( "RHEA:10575"^^xsd:string) "Catalysis of the reaction: vinylacetyl-CoA = crotonoyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.3"^^xsd:string) "delta3-cis-delta2-trans-enoyl-CoA isomerase"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.3"^^xsd:string) "vinylacetyl coenzyme A isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.3.3"^^xsd:string) "vinylacetyl-CoA delta3-delta2-isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.103"^^xsd:string) "viomycin phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.103"^^xsd:string) "capreomycin phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.103"^^xsd:string) Annotation( "MetaCyc:VIOMYCIN-KINASE-RXN"^^xsd:string) "Catalysis of the reaction: ATP + viomycin = ADP + O-phosphoviomycin."^^xsd:string) AnnotationAssertion(rdfs:label "viomycin kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.103"^^xsd:string) "ATP:viomycin O-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.105"^^xsd:string) "UDP-glucose:vitexin 2''-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "vitexin b-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.105"^^xsd:string) "uridine diphosphoglucose-vitexin 2''-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "vitexin beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.105"^^xsd:string) Annotation( "RHEA:21959"^^xsd:string) "Catalysis of the reaction: UDP-D-glucose + vitexin = H(+) + UDP + vitexin 2''-O-beta-D-glucoside."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.105"^^xsd:string) "UDPglucose:vitexin 2''-O-beta-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "vomifoliol 4'-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.221"^^xsd:string) "vomifoliol:NAD+ 4'-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.221"^^xsd:string) Annotation( "RHEA:22807"^^xsd:string) "Catalysis of the reaction: (6S,9R)-6-hydroxy-3-oxo-alpha-ionol + NAD(+) = (6S)-6-hydroxy-3-oxo-alpha-ionone + H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Watasenia-luciferin 2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.8"^^xsd:string) "luciferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.8"^^xsd:string) Annotation( "MetaCyc:WATASEMIA-LUCIFERIN-2-MONOOXYGENASE-RXN"^^xsd:string) "Catalysis of the reaction: Watasenia luciferin + O2 = oxidized Watasenia luciferin + CO2 + light."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.8"^^xsd:string) "Watasenia-type luciferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.8"^^xsd:string) "Watasenia-luciferin:oxygen 2-oxidoreductase (decarboxylating)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.50"^^xsd:string) Annotation( "MetaCyc:WAX-ESTER-HYDROLASE-RXN"^^xsd:string) "Catalysis of the reaction: a wax ester + H2O = a long-chain alcohol + a long-chain carboxylate."^^xsd:string) AnnotationAssertion(rdfs:label "wax-ester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.50"^^xsd:string) "jojoba wax esterase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.50"^^xsd:string) "wax-ester acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.50"^^xsd:string) "WEH"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.41"^^xsd:string) "5,12-dihydroxanthommatin:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "xanthommatin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.41"^^xsd:string) Annotation( "RHEA:13420"^^xsd:string) "Catalysis of the reaction: 5,12-dihydroxanthommatin + NAD(+) = H(+) + NADH + xanthommatin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "xylitol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.122"^^xsd:string) "ATP:xylitol 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.122"^^xsd:string) "xylitol phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.122"^^xsd:string) Annotation( "RHEA:20212"^^xsd:string) "Catalysis of the reaction: ATP + xylitol = ADP + 2 H(+) + xylitol 5-phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.82"^^xsd:string) "D-xylonate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.82"^^xsd:string) Annotation( "RHEA:19160"^^xsd:string) "Catalysis of the reaction: D-xylonate = 2-dehydro-3-deoxy-D-arabinonate + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.82"^^xsd:string) "D-xylonate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.82"^^xsd:string) "D-xylonate hydro-lyase (2-dehydro-3-deoxy-D-xylonate-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "xylonate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.82"^^xsd:string) "D-xylo-aldonate dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.68"^^xsd:string) "xylono-g-lactonase activity"^^xsd:string) AnnotationAssertion(rdfs:label "xylono-1,4-lactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.68"^^xsd:string) "xylonolactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.68"^^xsd:string) "D-xylono-1,4-lactone lactonohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.68"^^xsd:string) Annotation( "MetaCyc:XYLONO-14-LACTONASE-RXN"^^xsd:string) "Catalysis of the reaction: D-xylono-1,4-lactone + H2O = D-xylonate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.203"^^xsd:string) "uridine diphosphoglucose-zeatin O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.203"^^xsd:string) "UDPglucose:trans-zeatin O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trans-zeatin O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "zeatin O-b-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.203"^^xsd:string) "UDP-glucose:trans-zeatin O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.203"^^xsd:string) "zeatin O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.203"^^xsd:string) "zeatin O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.203"^^xsd:string) Annotation( "RHEA:23227"^^xsd:string) "Catalysis of the reaction: trans-zeatin + UDP-D-glucose = O-beta-D-glucosyl-trans-zeatin + H(+) + UDP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.40"^^xsd:string) "zeatin O-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.40"^^xsd:string) Annotation( "RHEA:14724"^^xsd:string) "Catalysis of the reaction: UDP-alpha-D-xylose + zeatin = O-beta-D-xylosylzeatin + H(+) + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.40"^^xsd:string) "UDP-D-xylose:zeatin O-beta-D-xylosyltransferase activity"^^xsd:string) AnnotationAssertion( "zeatin O-b-D-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "zeatin O-beta-D-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.40"^^xsd:string) "uridine diphosphoxylose-zeatin xylosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.11.27"^^xsd:string) "acetyl-CoA carboxylase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.27"^^xsd:string) "acetyl-CoA carboxylase kinase (AMP-activated) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.27"^^xsd:string) "acetyl-CoA carboxylase kinase-2 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.27"^^xsd:string) "ACK3"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.27"^^xsd:string) "AMPK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.27"^^xsd:string) "acetyl-CoA carboxylase kinase-3 (AMP-activated) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.27"^^xsd:string) "I-peptide kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.27"^^xsd:string) "acetyl-CoA carboxylase kinase (cAMP-independent) activity"^^xsd:string) AnnotationAssertion( "Catalysis of the reaction: ATP + [acetyl-CoA carboxylase] = ADP + [acetyl-CoA carboxylase] phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.27"^^xsd:string) "ACK2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.27"^^xsd:string) "STK5"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.27"^^xsd:string) "acetyl coenzyme A carboxylase kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.27"^^xsd:string) "acetyl-coenzyme A carboxylase kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.27"^^xsd:string) "ATP:acetyl-CoA carboxylase phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.27"^^xsd:string) "acetyl-CoA carboxylase bound kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[acetyl-CoA carboxylase] kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.11.27"^^xsd:string) "acetyl-CoA carboxylase kinase 2 activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.44"^^xsd:string) Annotation( "MetaCyc:ACETYL-COA-CARBOXYLASE-PHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: [acetyl-CoA carboxylase]-phosphate + H2O = [acetyl-CoA carboxylase] + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.44"^^xsd:string) "acetyl-CoA:carbon-dioxide ligase (ADP-forming)-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.44"^^xsd:string) "acetyl-CoA carboxylase-phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[acetyl-CoA carboxylase]-phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.42"^^xsd:string) "phosphatase type 2oC"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.42"^^xsd:string) "Mg2+ dependent glycogen synthase phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.42"^^xsd:string) "UDPglucose:glycogen 4-alpha-D-glucosyltransferase-D phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.42"^^xsd:string) "glycogen glucosyltransferase phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.42"^^xsd:string) Annotation( "MetaCyc:GLYCOGEN-SYNTHASE-D-PHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: [glycogen-synthase D] + H2O = [glycogen-synthase I] + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.42"^^xsd:string) "UDPglucose-glycogen glucosyltransferase phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.42"^^xsd:string) "UDP-glucose:glycogen 4-alpha-D-glucosyltransferase-D phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.42"^^xsd:string) "UDP-glycogen glucosyltransferase phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.42"^^xsd:string) "glycogen synthase phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.42"^^xsd:string) "glycogen synthetase phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[glycogen-synthase-D] phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.42"^^xsd:string) "glycogen-synthase-D phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.42"^^xsd:string) "glycogen synthase D phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.42"^^xsd:string) "uridine diphosphoglucose-glycogen glucosyltransferase phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.49"^^xsd:string) "pyruvate kinase phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "[pyruvate kinase]-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.49"^^xsd:string) "ATP:pyruvate 2-O-phosphotransferase-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.49"^^xsd:string) Annotation( "MetaCyc:PYRUVATE-KINASE-PHOSPHATASE-RXN"^^xsd:string) "Catalysis of the reaction: [pyruvate kinase] phosphate + H2O = [pyruvate kinase] + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.49"^^xsd:string) "pyruvate kinase-phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.34"^^xsd:string) "UDP-L-arabinose:(indol-3-yl)acetyl-myo-inositol L-arabinosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "indolylacetylinositol arabinosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.34"^^xsd:string) Annotation( "RHEA:19508"^^xsd:string) "Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-L-arabinose = (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + H(+) + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.34"^^xsd:string) "UDP-L-arabinose:indol-3-ylacetyl-myo-inositol L-arabinosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.34"^^xsd:string) "arabinosylindolylacetylinositol synthase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.56"^^xsd:string) Annotation( "RHEA:13388"^^xsd:string) "Catalysis of the reaction: 3-oxolaurate + H(+) = 2-undecanone + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.56"^^xsd:string) "beta-ketolaurate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.56"^^xsd:string) "3-oxododecanoate carboxy-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-oxolaurate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.56"^^xsd:string) "beta-ketoacyl decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.56"^^xsd:string) "3-oxododecanoate carboxy-lyase (2-undecanone-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "agaritine g-glutamyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.9"^^xsd:string) Annotation( "MetaCyc:AGARITINE-GAMMA-GLUTAMYLTRANSFERASE-RXN"^^xsd:string) "Catalysis of the reaction: agaritine + acceptor-NH2 = 4-hydroxymethylphenylhydrazine + gamma-L-glutamyl-acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "agaritine gamma-glutamyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.9"^^xsd:string) "(gamma-L-glutamyl)-N1-(4-hydroxymethylphenyl)hydrazine:(acceptor) gamma-glutamyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.2.9"^^xsd:string) "(gamma-L-glutamyl)-1-N-(4-hydroxymethylphenyl)hydrazine:(acceptor) gamma-glutamyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.177"^^xsd:string) "uridine diphosphoglucose-cinnamate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.177"^^xsd:string) Annotation( "RHEA:13440"^^xsd:string) "Catalysis of the reaction: trans-cinnamate + UDP-D-glucose = 1-O-trans-cinnamoyl-beta-D-glucopyranose + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.177"^^xsd:string) "UDP-glucose:trans-cinnamate beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.177"^^xsd:string) "UDPglucose:trans-cinnamate beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "cinnamate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.177"^^xsd:string) "UDPG:t-cinnamate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cinnamate beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "cinnamate b-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-alanine 2-hydroxymethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.7"^^xsd:string) Annotation( "RHEA:10067"^^xsd:string) "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + D-alanine + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + 2-methylserine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.7"^^xsd:string) "2-methylserine hydroxymethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.2.7"^^xsd:string) "5,10-methylenetetrahydrofolate:D-alanine 2-hydroxymethyltransferase activity"^^xsd:string) AnnotationAssertion( "D-alanine hydroxymethyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.5"^^xsd:string) "N-formimidoyl-L-aspartate iminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.5"^^xsd:string) Annotation( "MetaCyc:FORMIMINOASPARTATE-DEIMINASE-RXN"^^xsd:string) "Catalysis of the reaction: N-formimidoyl-L-aspartate + H2O = N-formyl-L-aspartate + NH3."^^xsd:string) AnnotationAssertion( "formiminoaspartate deiminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "formimidoylaspartate deiminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.8"^^xsd:string) "N-formiminoglutamate hydrolase activity"^^xsd:string) AnnotationAssertion( "formiminoglutamase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.8"^^xsd:string) "N-formimidoyl-L-glutamate formimidoylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.8"^^xsd:string) "formiminoglutamate hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "formimidoylglutamase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.8"^^xsd:string) Annotation( "RHEA:22495"^^xsd:string) "Catalysis of the reaction: N-formimidoyl-L-glutamate + H(2)O = L-glutamate + formamide."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.8"^^xsd:string) "N-formimino-L-glutamate formiminohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.3.13"^^xsd:string) Annotation( "MetaCyc:FORMIMINOGLUTAMATE-DEIMINASE-RXN"^^xsd:string) "Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = N-formyl-L-glutamate + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.13"^^xsd:string) "formiminoglutamic iminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.3.13"^^xsd:string) "N-formimidoyl-L-glutamate iminohydrolase activity"^^xsd:string) AnnotationAssertion( "formiminoglutamate deiminase activity"^^xsd:string) AnnotationAssertion(rdfs:label "formimidoylglutamate deiminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.38"^^xsd:string) "glutaminase-asparaginase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.38"^^xsd:string) Annotation( "MetaCyc:GLUTAMINASE-ASPARAGIN-ASE-RXN"^^xsd:string) "Catalysis of the reaction: H2O + L-glutamine = NH3 + L-glutamate; and H2O + L-asparagine = NH3 + L-aspartate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.38"^^xsd:string) "L-asparagine/L-glutamine amidohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamin-(asparagin-)ase activity"^^xsd:string) AnnotationAssertion( "glutaminase-(asparagin-)ase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.38"^^xsd:string) "L-ASNase/L-GLNase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.38"^^xsd:string) "L-glutamine(L-asparagine) amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.99.1"^^xsd:string) "ammonia:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.99.1"^^xsd:string) Annotation( "MetaCyc:HYDROXYLAMINE-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: NH3 + H2O + acceptor = hydroxylamine + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.99.1"^^xsd:string) "hydroxylamine (acceptor) reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydroxylamine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.99.1"^^xsd:string) "ammonia:(acceptor) oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroxymandelonitrile lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.11"^^xsd:string) "(S)-4-hydroxymandelonitrile 4-hydroxybenzaldehyde-lyase (cyanide-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.11"^^xsd:string) "(S)-4-hydroxymandelonitrile hydroxybenzaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.11"^^xsd:string) "hydroxynitrile lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.11"^^xsd:string) Annotation( "MetaCyc:HYDROXYMANDELONITRILE-LYASE-RXN"^^xsd:string) "Catalysis of the reaction: 4-hydroxymandelonitrile = 4-hydroxybenzaldehyde + hydrocyanate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.11"^^xsd:string) "sorghum hydroxynitrile lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.139"^^xsd:string) Annotation( "MetaCyc:MALTOSE-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: 2 alpha-D-glucose 1-phosphate = maltose + 2 phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "maltose synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.139"^^xsd:string) "alpha-D-glucose-1-phosphate:alpha-D-glucose-1-phosphate 4-alpha-D-glucosyltransferase (dephosphorylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nitrite reductase (NO-forming) activity"^^xsd:string) AnnotationAssertion( "nitrite reductase (cytochrome) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.1"^^xsd:string) "cytochrome cd1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.1"^^xsd:string) "cytochrome c-551:O2, NO2+ oxidoreductase activity"^^xsd:string) AnnotationAssertion( "nitrite reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.1"^^xsd:string) "nitrite reductase (cytochrome; NO-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.1"^^xsd:string) "methyl viologen-nitrite reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.1"^^xsd:string) Annotation( "MetaCyc:NITRITE-REDUCTASE-CYTOCHROME-RXN"^^xsd:string) "Catalysis of the reaction: nitric oxide + H2O + ferricytochrome c = nitrite + ferrocytochrome c + 2 H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.1"^^xsd:string) "[nitrite reductase (cytochrome)]"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.1"^^xsd:string) "cytochrome c-551:O(2), NO(2)(+) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.1"^^xsd:string) "cytochrome cd activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.1"^^xsd:string) "Pseudomonas cytochrome oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.1"^^xsd:string) "cd-cytochrome nitrite reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.1"^^xsd:string) "nitric-oxide:ferricytochrome-c oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.105"^^xsd:string) "strictosidine beta-D-glucohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "strictosidine beta-glucosidase activity"^^xsd:string) AnnotationAssertion( "strictosidine b-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.105"^^xsd:string) Annotation( "RHEA:12920"^^xsd:string) "Catalysis of the reaction: 3alpha(S)-strictosidine + H(2)O = D-glucose + strictosidine aglycone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.23"^^xsd:string) "thiamin:oxygen 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiamine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.23"^^xsd:string) "thiamin dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "thiamin oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.23"^^xsd:string) Annotation( "MetaCyc:THIAMIN-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: thiamine + 2 O2 = thiamine acetic acid + 2 H2O2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.23"^^xsd:string) "thiamine:oxygen 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.23"^^xsd:string) "thiamine dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.4.3"^^xsd:string) "Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate. This reaction requires Ca2+."^^xsd:string) AnnotationAssertion(rdfs:label "calcium-dependent phospholipase C activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "transforming growth factor beta ligand binding to type II receptor"^^xsd:string) AnnotationAssertion( "transforming growth factor beta ligand binding to type I receptor"^^xsd:string) AnnotationAssertion( "TGF-beta binding"^^xsd:string) AnnotationAssertion( "TGFbeta binding"^^xsd:string) AnnotationAssertion(rdfs:label "transforming growth factor beta binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "microfibril binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a microfibril, any small fibril occurring in biological material."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.10"^^xsd:string) "geranyl pyrophosphate:(-)-endo-fenchol cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.10"^^xsd:string) "(-)-endo-fenchol cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.10"^^xsd:string) "geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-endo-fenchol-forming]"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.10"^^xsd:string) Annotation( "RHEA:20568"^^xsd:string) "Catalysis of the reaction: geranyl diphosphate + H(2)O = (-)-endo-fenchol + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "(-)-endo-fenchol synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.3.6"^^xsd:string) "acetyl-CoA:2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.6"^^xsd:string) Annotation( "RHEA:23043"^^xsd:string) "Catalysis of the reaction: 2-oxobutanate + acetyl-CoA + H(2)O = (R)-2-ethylmalate + CoA + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.6"^^xsd:string) "propylmalate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.6"^^xsd:string) "(R)-2-ethylmalate 2-oxobutanoyl-lyase (CoA-acetylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.6"^^xsd:string) "2-ethylmalate-3-hydroxybutanedioate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.6"^^xsd:string) "propylmalic synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-ethylmalate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.2.1.5"^^xsd:string) "2-hydroxy-3-oxoadipate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.5"^^xsd:string) "oxoglutarate: glyoxylate carboligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.5"^^xsd:string) "alpha-ketoglutaric-glyoxylic carboligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.5"^^xsd:string) "2-oxoglutarate:glyoxylate succinaldehydetransferase (decarboxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxy-3-oxoadipate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.5"^^xsd:string) Annotation( "RHEA:14344"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + glyoxylate + H(+) = 2-hydroxy-3-oxoadipate + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.5"^^xsd:string) "2-hydroxy-3-oxoadipate glyoxylate-lyase (carboxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.5"^^xsd:string) "oxoglutarate:glyoxylate carboligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.3.5"^^xsd:string) "MCS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.5"^^xsd:string) "propanoyl-CoA:oxaloacetate C-propanoyltransferase (thioester-hydrolysing, 1-carboxyethyl-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.5"^^xsd:string) "methylcitrate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.5"^^xsd:string) Annotation( "RHEA:23783"^^xsd:string) "Catalysis of the reaction: H(2)O + oxaloacetate + propanoyl-CoA = (2R,3S)-2-methylcitrate + CoA + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.5"^^xsd:string) "methylcitrate synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-methylcitrate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.5"^^xsd:string) "2-methylcitrate oxaloacetate-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-ethylmalate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.7"^^xsd:string) "3-ethylmalate glyoxylate-lyase (CoA-butanoylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.7"^^xsd:string) "2-ethyl-3-hydroxybutanedioate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.7"^^xsd:string) "butanoyl-CoA:glyoxylate C-butanoyltransferase (thioester-hydrolysing, 1-carboxypropyl-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.7"^^xsd:string) Annotation( "RHEA:10503"^^xsd:string) "Catalysis of the reaction: butanoyl-CoA + glyoxylate + H(2)O = 3-ethylmalate + CoA + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.3.12"^^xsd:string) "3-propylmalate glyoxylate-lyase (CoA-pentanoylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.12"^^xsd:string) "beta-n-propylmalate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.12"^^xsd:string) "3-(n-propyl)-malate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.12"^^xsd:string) "N-propylmalate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.12"^^xsd:string) "pentanoyl-CoA:glyoxylate C-pentanoyltransferase (thioester-hydrolysing, 1-carboxybutyl-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "3-propylmalate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.12"^^xsd:string) Annotation( "RHEA:14460"^^xsd:string) "Catalysis of the reaction: glyoxylate + H(2)O + pentanoyl-CoA = 3-propylmalate + CoA + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aquacobalamin reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.5"^^xsd:string) "aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.5"^^xsd:string) "NADPH2:aquacob(III)alamin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.5"^^xsd:string) "NADPH:aquacob(III)alamin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.5"^^xsd:string) Annotation( "MetaCyc:AQUACOBALAMIN-REDUCTASE-NADPH-RXN"^^xsd:string) "Catalysis of the reaction: 2 cob(II)alamin + NADP+ = 2 aquacob(III)alamin + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.5"^^xsd:string) "NADPH-linked aquacobalamin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.5"^^xsd:string) "cob(II)alamin:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.5"^^xsd:string) "aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.1.11"^^xsd:string) "NADH:asparagusate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.11"^^xsd:string) "asparagusic dehydrogenase activity"^^xsd:string) AnnotationAssertion( "asparagusate reductase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.11"^^xsd:string) "NADH2:asparagusate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.11"^^xsd:string) "3-mercapto-2-mercaptomethylpropanoate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.11"^^xsd:string) "asparagusate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.11"^^xsd:string) Annotation( "RHEA:14884"^^xsd:string) "Catalysis of the reaction: 3-mercapto-2-mercaptomethylpropanoate + NAD(+) = asparagusate + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.11"^^xsd:string) "asparagusate reductase (NADH2)"^^xsd:string) AnnotationAssertion(rdfs:label "asparagusate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "NADPH:4-(dimethylamino)azobenzene oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "NADPH2:4-(dimethylamino)azobenzene oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "orange I azoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "dibromopropylaminophenylazobenzoic azoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "p-dimethylaminoazobenzene azoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "orange II azoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "New coccine (NC)-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "azoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "NADPH2-dependent azoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "methyl red azoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "azobenzene reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "N,N-dimethyl-1,4-phenylenediamine, aniline:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "NAD(P)H:1-(4'-sulfophenylazo)-2-naphthol oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "NADPH-dependent azoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "new coccine (NC)-reductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "nicotinamide adenine dinucleotide (phosphate) azoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "NC-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "dimethylaminobenzene reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "N,N-dimethyl-4-phenylazoaniline azoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "p-aminoazobenzene reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "azo-dye reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) "azo reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.6"^^xsd:string) Annotation( "MetaCyc:AZOBENZENE-REDUCTASE-RXN"^^xsd:string) "Catalysis of the reaction: N,N-dimethyl-1,4-phenylenediamine + aniline + NADP+ = 4-(dimethylamino)azobenzene + NADPH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.50"^^xsd:string) "3-O-acetyl-L-serine:zeatin 2-amino-2-carboxyethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.50"^^xsd:string) Annotation( "RHEA:17336"^^xsd:string) "Catalysis of the reaction: O-acetyl-L-serine + zeatin = L-lupinate + acetate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.50"^^xsd:string) "lupinate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.50"^^xsd:string) "lupinic acid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.50"^^xsd:string) "O-acetyl-L-serine acetate-lyase (adding N6-substituted adenine)"^^xsd:string) AnnotationAssertion( "beta-(9-cytokinin)-alanine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.50"^^xsd:string) "O3-acetyl-L-serine:zeatin 2-amino-2-carboxyethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.50"^^xsd:string) "lupinic acid synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "zeatin 9-aminocarboxyethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.50"^^xsd:string) "O-acetyl-L-serine acetate-lyase (adding N(6)-substituted adenine) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.50"^^xsd:string) "beta-(9-cytokinin)alanine synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.21.99.1"^^xsd:string) Annotation( "RHEA:14526"^^xsd:string) "Catalysis of the reaction: beta-cyclopiazonate + A = alpha-cyclopiazonate + AH(2)."^^xsd:string) AnnotationAssertion( "b-cyclopiazonate dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-cyclopiazonate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.99.1"^^xsd:string) "beta-cyclopiazonate oxidocyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.99.1"^^xsd:string) "beta-cyclopiazonic oxidocyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.99.1"^^xsd:string) "beta-cyclopiazonate:acceptor oxidoreductase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.99.1"^^xsd:string) "beta-cyclopiazonate:(acceptor) oxidoreductase (cyclizing)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.8"^^xsd:string) "geranylgeranyl-diphosphate diphosphate-lyase (cyclizing)"^^xsd:string) AnnotationAssertion(rdfs:label "casbene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.8"^^xsd:string) "geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, casbene-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.8"^^xsd:string) "casbene synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.8"^^xsd:string) Annotation( "RHEA:14904"^^xsd:string) "Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = casbene + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.3.3"^^xsd:string) "Re-citrate-synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.3"^^xsd:string) "acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-R)-carboxymethyl-forming]"^^xsd:string) AnnotationAssertion(rdfs:label "citrate (Re)-synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.3"^^xsd:string) "(R)-citrate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.3"^^xsd:string) "citrate oxaloacetate-lyase [(pro-3R)-CH2COO-rightacetyl-CoA]"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.3"^^xsd:string) "citrate oxaloacetate-lyase ((pro-3R)-CH(2)COO(-)->acetyl-CoA) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.3"^^xsd:string) Annotation( "ISBN:0121227073"^^xsd:string) Annotation( "MetaCyc:CITRATE-RE-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the re-face of oxaloacetate; acetyl-CoA provides the two carbon atoms of the pro-R carboxymethyl group."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.1.14"^^xsd:string) "CoA-disulfide reductase (NADH2)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.14"^^xsd:string) "CoADR activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.14"^^xsd:string) "NADH:CoA-disulfide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.14"^^xsd:string) "CoA:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.14"^^xsd:string) Annotation( "MetaCyc:COA-DISULFIDE-REDUCTASE-NADH-RXN"^^xsd:string) "Catalysis of the reaction: 2 CoA + NAD+ = CoA-disulfide + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.14"^^xsd:string) "NADH2:CoA-disulfide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.14"^^xsd:string) "CoA:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "CoA-disulfide reductase activity"^^xsd:string) AnnotationAssertion( "CoA-disulphide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.14"^^xsd:string) "coenzyme A disulfide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.14"^^xsd:string) "CoA-disulfide reductase [NAD(P)H]"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.14"^^xsd:string) "CoA-disulfide reductase (NAD(P)H) activity"^^xsd:string) AnnotationAssertion( "CoA-disulfide reductase (NADH) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.1.10"^^xsd:string) "coenzyme A glutathione disulfide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.10"^^xsd:string) "NADPH2:CoA-glutathione oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.10"^^xsd:string) "NADPH:CoA-glutathione oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.10"^^xsd:string) "coenzyme A disulfide-glutathione reductase activity"^^xsd:string) AnnotationAssertion( "CoA-glutathione reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.10"^^xsd:string) "NADPH-dependent coenzyme A-SS-glutathione reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.10"^^xsd:string) "glutathione:NADP+ oxidoreductase (CoA-acylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.10"^^xsd:string) Annotation( "MetaCyc:COA-GLUTATHIONE-REDUCTASE-NADPH-RXN"^^xsd:string) "Catalysis of the reaction: CoA + glutathione + NADP+ = CoA-glutathione + NADPH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "CoA-glutathione reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.16.1.4"^^xsd:string) "vitamin B(12r) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.4"^^xsd:string) "B12r reductase activity"^^xsd:string) AnnotationAssertion( "vitamin B12 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.4"^^xsd:string) "NADH2:cob(II)alamin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.4"^^xsd:string) "B(12r) reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cob(II)alamin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.4"^^xsd:string) "NADH:cob(II)alamin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.4"^^xsd:string) Annotation( "RHEA:17484"^^xsd:string) "Catalysis of the reaction: 2 cob(I)alamin + H(+) + NAD(+) = 2 cob(II)alamin + NADH."^^xsd:string) AnnotationAssertion( "vitamin B12 reduction"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.4"^^xsd:string) "cob(I)alamin:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.16.1.4"^^xsd:string) "vitamin B12r reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.12.98.1"^^xsd:string) "F420-reducing hydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "coenzyme F420 hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.98.1"^^xsd:string) Annotation( "RHEA:23763"^^xsd:string) "Catalysis of the reaction: coenzyme F420 + H(2) + H(+) = reduced coenzyme F420."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.98.1"^^xsd:string) "coenzyme F420-dependent hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.98.1"^^xsd:string) "8-hydroxy-5-deazaflavin-reducing hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.98.1"^^xsd:string) "hydrogen:coenzyme F420 oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.21.3.2"^^xsd:string) Annotation( "RHEA:23567"^^xsd:string) "Catalysis of the reaction: 2 columbamine + O(2) = 2 berberine + 2 H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.3.2"^^xsd:string) "berberine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.3.2"^^xsd:string) "columbamine:oxygen oxidoreductase (cyclizing)"^^xsd:string) AnnotationAssertion(rdfs:label "columbamine oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.1.6"^^xsd:string) "NADH-dependent cystine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.6"^^xsd:string) "L-cysteine:NAD+ oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.6"^^xsd:string) "cystine reductase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.6"^^xsd:string) "NADH2:L-cystine oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.6"^^xsd:string) "cystine reductase (NADH2)"^^xsd:string) AnnotationAssertion(rdfs:label "cystine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.6"^^xsd:string) "NADH:L-cystine oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.6"^^xsd:string) Annotation( "RHEA:20600"^^xsd:string) "Catalysis of the reaction: 2 L-cysteine + NAD(+) = L-cystine + H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.3.2"^^xsd:string) "dodecanoyl-CoA:oxaloacetate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.2"^^xsd:string) "2-decylcitrate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.2"^^xsd:string) "(2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase (CoA- acylating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "decylcitrate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.2"^^xsd:string) "(2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase (CoA-acylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.2"^^xsd:string) Annotation( "RHEA:16608"^^xsd:string) "Catalysis of the reaction: H(2)O + lauroyl-CoA + oxaloacetate = (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate + CoA + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "decylhomocitrate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.4"^^xsd:string) "3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.4"^^xsd:string) "dodecanoyl-CoA:2-oxoglutarate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.4"^^xsd:string) "2-decylhomocitrate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.4"^^xsd:string) "3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase (CoA- acylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.4"^^xsd:string) Annotation( "RHEA:10367"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + H(2)O + lauroyl-CoA = (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.2"^^xsd:string) Annotation( "RHEA:17892"^^xsd:string) "Catalysis of the reaction: H(2)O + phosphoethanolamine = acetaldehyde + NH(4)(+) + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.2"^^xsd:string) "ethanolamine-phosphate phospho-lyase (deaminating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.2"^^xsd:string) "O-phosphorylethanol-amine phospho-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ethanolamine-phosphate phospho-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.2"^^xsd:string) "O-phosphoethanolamine-phospholyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.2"^^xsd:string) "amino alcohol O-phosphate phospholyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.2"^^xsd:string) "ethanolamine-phosphate phospho-lyase (deaminating; acetaldehyde-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.1.10"^^xsd:string) "NADH-hydroxylamine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.10"^^xsd:string) "ammonium:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.10"^^xsd:string) Annotation( "MetaCyc:HYDROXYLAMINE-REDUCTASE-NADH-RXN"^^xsd:string) "Catalysis of the reaction: NH3 + NAD+ + H2O = hydroxylamine + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.10"^^xsd:string) "NADH:hydroxylamine oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.10"^^xsd:string) "N-hydroxy amine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.10"^^xsd:string) "hydroxylamine reductase (NADH2)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.10"^^xsd:string) "ammonium dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.10"^^xsd:string) "NADH2:hydroxylamine oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydroxylamine reductase (NADH) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.52"^^xsd:string) "3-O-acetyl-L-serine:3,4-dihydroxypyridine 1-(2-amino-2-carboxyethyl)transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.52"^^xsd:string) "O3-acetyl-L-serine acetate-lyase (adding 3,4-dihydroxypyridin-1-yl)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.52"^^xsd:string) Annotation( "RHEA:12696"^^xsd:string) "Catalysis of the reaction: 3,4-dihydroxypyridine + O-acetyl-L-serine = 3-(3,4-dihydroxypyridinium-1-yl)-L-alanine + acetate."^^xsd:string) AnnotationAssertion(rdfs:label "L-mimosine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.52"^^xsd:string) "O(3)-acetyl-L-serine acetate-lyase (adding 3,4-dihydroxypyridin-1-yl) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.52"^^xsd:string) "O3-acetyl-L-serine:3,4-dihydroxypyridine 1-(2-amino-2-carboxyethyl)transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-acetylneuraminate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.56"^^xsd:string) "phosphoenolpyruvate:N-acetyl-D-mannosamine C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.56"^^xsd:string) "(NANA)condensing enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.56"^^xsd:string) Annotation( "MetaCyc:N-ACETYLNEURAMINATE-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = phosphate + N-acetylneuraminate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.56"^^xsd:string) "N-acetylneuraminate pyruvate-lyase (pyruvate-phosphorylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.56"^^xsd:string) "NeuAc synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.56"^^xsd:string) "N-acetylneuraminic acid synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.1.2"^^xsd:string) "nitrate reductase [NAD(P)H2]"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.2"^^xsd:string) Annotation( "MetaCyc:NITRATE-REDUCTASE-NADPH-RXN"^^xsd:string) "Catalysis of the reaction: nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.2"^^xsd:string) "assimilatory nitrate reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nitrate reductase [NAD(P)H] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.2"^^xsd:string) "nitrate reductase (reduced nicotinamide adenine dinucleotide (phosphate)) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.2"^^xsd:string) "NAD(P)H bispecific nitrate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.2"^^xsd:string) "assimilatory NAD(P)H-nitrate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.2"^^xsd:string) "NAD(P)H2:nitrate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.2"^^xsd:string) "NAD(P)H:nitrate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.2"^^xsd:string) "nitrite:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.2"^^xsd:string) "nitrate reductase NAD(P)H activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.2"^^xsd:string) "NAD(P)H-nitrate reductase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.1.3"^^xsd:string) "NADPH-nitrate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.3"^^xsd:string) Annotation( "MetaCyc:NITRATE-REDUCTASE-NADPH-RXN"^^xsd:string) "Catalysis of the reaction: nitrite + NADP+ + H2O = nitrate + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.3"^^xsd:string) "nitrite:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.3"^^xsd:string) "NADPH:nitrate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.3"^^xsd:string) "nitrate reductase (NADPH(2)) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.3"^^xsd:string) "assimilatory NADPH-nitrate reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nitrate reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.3"^^xsd:string) "assimilatory reduced nicotinamide adenine dinucleotide phosphate-nitrate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.3"^^xsd:string) "nitrate reductase (NADPH2)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.3"^^xsd:string) "NADPH:nitrate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.3"^^xsd:string) "assimilatory nitrate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.3"^^xsd:string) "triphosphopyridine nucleotide-nitrate reductase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.1.9"^^xsd:string) "4NQO reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.9"^^xsd:string) "NAD(P)H:4-nitroquinoline-N-oxide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.9"^^xsd:string) "4-nitroquinoline 1-oxide reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nitroquinoline-N-oxide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.9"^^xsd:string) "4-(hydroxyamino)quinoline N-oxide:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.9"^^xsd:string) Annotation( "MetaCyc:1.7.1.9-RXN"^^xsd:string) "Catalysis of the reaction: 4-(hydroxyamino)quinoline N-oxide + 2 NAD(P)+ + H2O = 4-nitroquinoline N-oxide + 2 NAD(P)H + 2 H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.1.9"^^xsd:string) "NAD(P)H2:4-nitroquinoline-N-oxide oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.7"^^xsd:string) "pentalenene synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.7"^^xsd:string) "2-trans,6-trans-farnesyldiphosphate diphosphate-lyase (cyclizing, pentalenene-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.7"^^xsd:string) "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, pentalenene-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.7"^^xsd:string) Annotation( "RHEA:18084"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + pentalenene."^^xsd:string) AnnotationAssertion(rdfs:label "pentalenene synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.21.3.3"^^xsd:string) "berberine bridge enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.3.3"^^xsd:string) "berberine-bridge-forming enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.3.3"^^xsd:string) "BBE"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.3.3"^^xsd:string) "tetrahydroprotoberberine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.3.3"^^xsd:string) Annotation( "RHEA:19888"^^xsd:string) "Catalysis of the reaction: (S)-reticuline + O(2) = (S)-scoulerine + H(2)O(2) + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.21.3.3"^^xsd:string) "(S)-reticuline:oxygen oxidoreductase (methylene-bridge-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "reticuline oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.11"^^xsd:string) "sabinene hydrate cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.11"^^xsd:string) "geranyl-diphosphate diphosphate-lyase (cyclizing, sabinene-hydrate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.11"^^xsd:string) Annotation( "RHEA:19568"^^xsd:string) "Catalysis of the reaction: geranyl diphosphate + H(2)O = diphosphate + sabinene hydrate."^^xsd:string) AnnotationAssertion(rdfs:label "sabinene-hydrate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.8.2"^^xsd:string) "TMADh activity"^^xsd:string) AnnotationAssertion(rdfs:label "trimethylamine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.8.2"^^xsd:string) "trimethylamine:electron-transferring flavoprotein oxidoreductase (demethylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.8.2"^^xsd:string) Annotation( "MetaCyc:1.5.8.2-RXN"^^xsd:string) "Catalysis of the reaction: trimethylamine + H2O + electron-transferring flavoprotein = dimethylamine + formaldehyde + reduced electron-transferring flavoprotein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.53"^^xsd:string) "O3-acetyl-L-serine acetate-lyase (adding uracil)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.53"^^xsd:string) "O(3)-acetyl-L-serine acetate-lyase (adding uracil) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.53"^^xsd:string) "Willardiine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.53"^^xsd:string) Annotation( "MetaCyc:URACILYLALANINE-SYNTHASE-RXN"^^xsd:string) "Catalysis of the reaction: O3-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.53"^^xsd:string) "3-O-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.53"^^xsd:string) "isowillardiine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.53"^^xsd:string) "O3-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "uracilylalanine synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "zeatin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.69"^^xsd:string) Annotation( "RHEA:12760"^^xsd:string) "Catalysis of the reaction: dihydrozeatin + NADP(+) = H(+) + NADPH + zeatin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.69"^^xsd:string) "dihydrozeatin:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.33"^^xsd:string) "Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.33"^^xsd:string) "arachidonate omega(6) lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.33"^^xsd:string) "arachidonate:oxygen 15-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.33"^^xsd:string) "omega6 lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.33"^^xsd:string) "linoleic acid omega6-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.33"^^xsd:string) "arachidonate omega6 lipoxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arachidonate 15-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.33"^^xsd:string) "15-lipoxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(S)-norcoclaurine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.78"^^xsd:string) "4-hydroxyphenylacetaldehyde hydro-lyase [adding dopamine; (S)-norcoclaurine-forming]"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.78"^^xsd:string) "Catalysis of the reaction: 4-(2-aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde = (S)-norcoclaurine + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.78"^^xsd:string) "4-hydroxyphenylacetaldehyde hydro-lyase (adding dopamine)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.78"^^xsd:string) "(S)-norlaudanosoline synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.78"^^xsd:string) "acetylenedicarboxylate carboxy-lyase (pyruvate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.78"^^xsd:string) "acetylenedicarboxylate hydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetylenedicarboxylate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.78"^^xsd:string) "acetylenedicarboxylate hydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.78"^^xsd:string) "Catalysis of the reaction: H2O + acetylenedicarboxylate = CO2 + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.78"^^xsd:string) "acetylenedicarboxylate carboxy-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.17"^^xsd:string) "epsilon-lysine acylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acyl-lysine deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.17"^^xsd:string) "Catalysis of the reaction: H2O + N6-acyl-L-lysine = L-lysine + a carboxylate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.17"^^xsd:string) "N6-acyl-L-lysine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.17"^^xsd:string) "6-N-acyl-L-lysine amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "anthranilate 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.3"^^xsd:string) Annotation( "RHEA:21171"^^xsd:string) "Catalysis of the reaction: 5,6,7,8-tetrahydrobiopterin + anthranilate + O(2) = 3-hydroxyanthranilate + 7,8-dihydrobiopterin + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.3"^^xsd:string) "anthranilic acid hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.3"^^xsd:string) "anthranilate,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.3"^^xsd:string) "anthranilic hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "anthranilate 3-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.16.5"^^xsd:string) Annotation( "MetaCyc:GLYCERYL-ETHER-MONOOXYGENASE-RXN"^^xsd:string) "Catalysis of the reaction: 1-alkyl-sn-glycerol + O2 + (tetrahydrobiopterin/tetrahydropteridine) = 1-hydroxyalkyl-sn-glycerol + H2O + (dihydrobiopterin/dihydropteridine)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.5"^^xsd:string) "glyceryl-ether cleaving enzyme activity"^^xsd:string) AnnotationAssertion(rdfs:label "glyceryl-ether monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.5"^^xsd:string) "1-alkyl-sn-glycerol,tetrahydrobiopterin:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.5"^^xsd:string) "O-alkylglycerol monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.5"^^xsd:string) "alkylglycerol monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.5"^^xsd:string) "glyceryl etherase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.5"^^xsd:string) "glyceryl ether oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "imidazolonepropionase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.7"^^xsd:string) "imidazolone-5-propionate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.7"^^xsd:string) Annotation( "RHEA:23663"^^xsd:string) "Catalysis of the reaction: (S)-3-(4-oxo-4,5-dihydro-1H-imidazol-5-yl)propanoic acid + H(2)O = N-formimidoyl-L-glutamate + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.7"^^xsd:string) "3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.7"^^xsd:string) "4(5)-imidazolone-5(4)-propionic acid hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.7"^^xsd:string) "imidazolone propionic acid hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-mandelate 4-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.6"^^xsd:string) "(S)-2-hydroxy-2-phenylacetate,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "mandelate 4-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.6"^^xsd:string) "mandelic acid 4-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.16.6"^^xsd:string) Annotation( "RHEA:21719"^^xsd:string) "Catalysis of the reaction: (S)-mandelate + 5,6,7,8-tetrahydrobiopterin + O(2) = (S)-4-hydroxymandelate + 7,8-dihydrobiopterin + H(2)O. (S)-2-hydroxy-2-phenylacetate is also known as S-mandelate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IMP 5' nucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: 5'-IMP + H2O = inosine + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "IMP 5'-nucleotidase activity"^^xsd:string) AnnotationAssertion( "IMP-GMP specific 5'-nucleotidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "GMP 5' nucleotidase activity"^^xsd:string) AnnotationAssertion( "IMP-GMP specific 5'-nucleotidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "GMP 5'-nucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: 5'-GMP + H2O = guanosine + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulphide as acceptor"^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is disulfide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "intramolecular transferase activity, transferring hydroxy groups"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a hydroxyl group from one position to another within a single molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sulphoacetaldehyde acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.15"^^xsd:string) Annotation( "RHEA:24207"^^xsd:string) "Catalysis of the reaction: acetyl phosphate + sulfite = phosphate + sulfoacetaldehyde."^^xsd:string) AnnotationAssertion(rdfs:label "sulfoacetaldehyde acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.3.15"^^xsd:string) "acetyl-phosphate:sulfite S-acetyltransferase (acyl-phosphate hydrolysing, 2-oxoethyl-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:10073711"^^xsd:string) "Catalysis of the reaction: UDP-glucose + ecdysteroid = UDP + glucosyl-ecdysteroid."^^xsd:string) AnnotationAssertion( "ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ecdysteroid UDP-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.25"^^xsd:string) "1,4-lactone hydroxyacylhydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1,4-lactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.25"^^xsd:string) "gamma-lactonase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.25"^^xsd:string) Annotation( "MetaCyc:14-LACTONASE-RXN"^^xsd:string) "Catalysis of the reaction: H2O + a 1,4-lactone = a 4-hydroxyacid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.260"^^xsd:string) Annotation( "RHEA:24487"^^xsd:string) "Catalysis of the reaction: NAD(+) + sulcatol = H(+) + NADH + sulcatone."^^xsd:string) AnnotationAssertion(rdfs:label "sulcatone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.260"^^xsd:string) "sulcatol:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycerol-1-phosphate dehydrogenase [NAD(P)+] activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.261"^^xsd:string) Annotation( "MetaCyc:1.1.1.261-RXN"^^xsd:string) "Catalysis of the reaction: NAD(P)+ + sn-glycerol-1-phosphate = NAD(P)H + H+ + dihydroxy-acetone-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.261"^^xsd:string) "sn-glycerol-1-phosphate:NAD(P)+ 2-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "transferase activity, transferring alkylthio groups"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of an alkylthio group from one compound (donor) to another (acceptor)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and the latter donor is dehydrogenated."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a NAD(P)+ to NAD(P)H."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1,3-beta-galactosyl-N-acetylhexosamine phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.211"^^xsd:string) "beta-D-galactopyranosyl-(1->3)-N-acetyl-D-hexosamine:phosphate galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.211"^^xsd:string) Annotation( "MetaCyc:2.4.1.211-RXN"^^xsd:string) "Catalysis of the reaction: phosphate + beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine = N-acetyl-D-glucosamine + alpha-D-galactopyranose 1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.211"^^xsd:string) "beta-D-galactopyranosyl-(1,3)-N-acetyl-D-hexosamine:phosphate galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "beta-1,3-galactosyl-N-acetylhexosamine phosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.212"^^xsd:string) "spHAS"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.212"^^xsd:string) "HAS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.212"^^xsd:string) "alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1,4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hyaluronan synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.212"^^xsd:string) Annotation( "MetaCyc:2.4.1.212-RXN"^^xsd:string) "Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)](n) + 2n UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.212"^^xsd:string) "seHAS"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.212"^^xsd:string) "alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1->4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cis-zeatin O-b-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.215"^^xsd:string) Annotation( "RHEA:20684"^^xsd:string) "Catalysis of the reaction: cis-zeatin + UDP-D-glucose = O-beta-D-glucosyl-cis-zeatin + H(+) + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.215"^^xsd:string) "UDP-glucose:cis-zeatin O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.215"^^xsd:string) "UDPglucose:cis-zeatin O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cis-zeatin O-beta-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.216"^^xsd:string) "trehalose 6-phosphate:phosphate beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trehalose 6-phosphate phosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.216"^^xsd:string) Annotation( "MetaCyc:2.4.1.216-RXN"^^xsd:string) "Catalysis of the reaction: trehalose 6-phosphate + phosphate = glucose 6-phosphate + beta-D-glucose 1-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.217"^^xsd:string) "GDP-mannose:3-phosphoglycerate 3-alpha-D-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.217"^^xsd:string) Annotation( "RHEA:13540"^^xsd:string) "Catalysis of the reaction: 3-phospho-D-glycerate + GDP-alpha-D-mannose = 2-(alpha-D-mannosyl)-3-phosphoglycerate + GDP + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.217"^^xsd:string) "MPG synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannosyl-3-phosphoglycerate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.218"^^xsd:string) Annotation( "RHEA:12563"^^xsd:string) "Catalysis of the reaction: hydroquinone + UDP-D-glucose = H(+) + hydroquinone O-beta-D-glucopyranoside + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.218"^^xsd:string) "arbutin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.218"^^xsd:string) "UDPglucose:hydroquinone-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.218"^^xsd:string) "hydroquinone:O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydroquinone glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.218"^^xsd:string) "UDP-glucose:hydroquinone-O-beta-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.219"^^xsd:string) "UDP-glucose:vomilenine 21-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "vomilenine glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.219"^^xsd:string) Annotation( "RHEA:19388"^^xsd:string) "Catalysis of the reaction: UDP-D-glucose + vomilenine = H(+) + raucaffricine + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.219"^^xsd:string) "vomilenine-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.219"^^xsd:string) "UDPG:vomilenine 21-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.219"^^xsd:string) "UDPG:vomilenine 21beta-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.220"^^xsd:string) "indoxyl-UDPG-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "indoxyl-UDPG glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.220"^^xsd:string) "UDP-glucose:indoxyl 3-O-beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.220"^^xsd:string) Annotation( "RHEA:12007"^^xsd:string) "Catalysis of the reaction: indoxyl + UDP-D-glucose = H(+) + indican + UDP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.224"^^xsd:string) "alpha-N-acetylglucosaminyltransferase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.224"^^xsd:string) Annotation( "MetaCyc:2.4.1.224-RXN"^^xsd:string) "Catalysis of the reaction: beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP-N-acetyl-D-glucosamine = N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.224"^^xsd:string) "UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion( "glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-a-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.224"^^xsd:string) "glucuronyl-N-acetylglucosaminylproteoglycan alpha-1,4-N-acetylglucosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.225"^^xsd:string) "heparan glucuronyltransferase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.225"^^xsd:string) "UDP-alpha-D-glucuronate:N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 4-beta-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion( "N-acetylglucosaminyl-proteoglycan 4-b-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.225"^^xsd:string) Annotation( "MetaCyc:2.4.1.225-RXN"^^xsd:string) "Catalysis of the reaction: N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.225"^^xsd:string) "N-acetylglucosaminylproteoglycan beta-1,4-glucuronyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.226"^^xsd:string) Annotation( "MetaCyc:2.4.1.226-RXN"^^xsd:string) "Catalysis of the reaction: N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,3)-N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP."^^xsd:string) AnnotationAssertion( "N-acetylgalactosaminyl-proteoglycan 3-b-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.226"^^xsd:string) "chondroitin glucuronyltransferase II activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.226"^^xsd:string) "alpha-D-glucuronate:N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 3-beta-glucuronosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.227"^^xsd:string) "undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.227"^^xsd:string) Annotation( "MetaCyc:2.4.1.227-RXN"^^xsd:string) "Catalysis of the reaction: Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP."^^xsd:string) AnnotationAssertion( "undecaprenyldiphospho-muramoylpentapeptide b-N-acetylglucosaminyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.227"^^xsd:string) "UDP-N-acetyl-D-glucosamine:N-acetyl-alpha-D-muramyl(oyl-L-Ala- gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol beta-1,4-N-acetylglucosaminlytransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.227"^^xsd:string) "UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.227"^^xsd:string) "MurG transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.228"^^xsd:string) Annotation( "MetaCyc:2.4.1.228-RXN"^^xsd:string) "Catalysis of the reaction: beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = alpha-D-galactosyl-(1,4)-beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP."^^xsd:string) AnnotationAssertion(rdfs:label "lactosylceramide 4-alpha-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.228"^^xsd:string) "UDP-galactose:lactosylceramide 4II-alpha-D-galactosyltransferase activity"^^xsd:string) AnnotationAssertion( "lactosylceramide 4-a-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.228"^^xsd:string) "Gal-beta-(1,4)-Glc-beta-1-Cer alpha-(1,4)-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.228"^^xsd:string) "histo-blood group P(k) UDP-galactose activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.228"^^xsd:string) "Gal-beta-1,4-Glc-beta-1-Cer alpha-1,4-galactosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.228"^^xsd:string) "globotriaosylceramide/CD77 synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.228"^^xsd:string) "histo-blood group Pk UDP-galactose"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.38"^^xsd:string) "beta-1,2-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.38"^^xsd:string) "1,2-beta-xylosyltransferase activity"^^xsd:string) AnnotationAssertion( "glycoprotein 2-b-D-xylosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.38"^^xsd:string) Annotation( "RHEA:10615"^^xsd:string) "Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + UDP-alpha-D-xylose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-[beta-D-xylosyl-(1->2)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + H(+) + UDP."^^xsd:string) AnnotationAssertion(rdfs:label "glycoprotein 2-beta-D-xylosyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.45"^^xsd:string) Annotation( "MetaCyc:2.5.1.45-RXN"^^xsd:string) "Catalysis of the reaction: spermidine + putrescine = sym-homospermidine + propane-1,3-diamine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.45"^^xsd:string) "spermidine:putrescine 4-aminobutyltransferase (propane-1,3-diamine-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "homospermidine synthase (spermidine-specific) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.148"^^xsd:string) Annotation( "RHEA:18440"^^xsd:string) "Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.148"^^xsd:string) "4-diphosphocytidyl-2-C-methyl-D-erythritol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.148"^^xsd:string) "CMK activity"^^xsd:string) AnnotationAssertion( "4-diphosphocytidyl-2C-methyl-D-erythritol kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.148"^^xsd:string) "CDP-ME kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.148"^^xsd:string) "ATP:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol 2-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.60"^^xsd:string) "4-diphosphocytidyl-2-C-methyl-D-erythritol synthase activity"^^xsd:string) AnnotationAssertion( "MEP cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.60"^^xsd:string) "MCT activity"^^xsd:string) AnnotationAssertion( "CTP:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.60"^^xsd:string) Annotation( "RHEA:13432"^^xsd:string) "Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + CTP = 4-CDP-2-C-methyl-D-erythritol + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity"^^xsd:string) AnnotationAssertion( "4-diphosphocytidyl-2C-methyl-D-erythritol synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.61"^^xsd:string) "2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "holo-citrate lyase synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.61"^^xsd:string) Annotation( "MetaCyc:2.7.7.61-RXN"^^xsd:string) "Catalysis of the reaction: apo-citrate lyase + 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA = diphosphate + holo-citrate lyase."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.61"^^xsd:string) "CitX"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.61"^^xsd:string) "2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.61"^^xsd:string) "holo-ACP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.61"^^xsd:string) "2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.24"^^xsd:string) "CDPdiglyceride-choline O-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylcholine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.24"^^xsd:string) "CDP-diacylglycerol:choline O-phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.24"^^xsd:string) "PC synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.24"^^xsd:string) Annotation( "RHEA:14600"^^xsd:string) "Catalysis of the reaction: CDP-diacylglycerol + choline = 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.24"^^xsd:string) "CDP-diglyceride-choline O-phosphatidyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-glucan, water dikinase activity"^^xsd:string) AnnotationAssertion( "a-glucan, water dikinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.4"^^xsd:string) Annotation( "MetaCyc:2.7.9.4-RXN"^^xsd:string) "Catalysis of the reaction: ATP + alpha-glucan + H2O = AMP + phospho-alpha-glucan + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.4"^^xsd:string) "alpha-glucan,water dikinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.4"^^xsd:string) "GWD"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.4"^^xsd:string) "ATP:alpha-glucan, water phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.4"^^xsd:string) "starch-related R1 protein activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which phosphorus or arsenic acts as a hydrogen or electron donor and reduces a known acceptor other than disulfide, NAD or NADP."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on phosphorus or arsenic in donors, with other known acceptors"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "coenzyme-B sulfoethylthiotransferase activity"^^xsd:string) AnnotationAssertion( "coenzyme-B sulphoethylthiotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.4.1"^^xsd:string) Annotation( "RHEA:12535"^^xsd:string) "Catalysis of the reaction: coenzyme B + methyl-coenzyme M = coenzyme M-coenzyme B heterodisulfide + methane. Methyl-CoM is also known as 2-(methylthio)ethanesulfonate, coenzyme B as N-(7-mercaptoheptanoyl)threonine 3-O-phosphate, and coenzyme M-coenzyme B heterodisulfide as CoM-S-S-CoB."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.4.1"^^xsd:string) "methyl-CoM reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.4.1"^^xsd:string) "2-(methylthio)ethanesulfonate:N-(7-thioheptanoyl)-3-O-phosphothreonine S-(2-sulfoethyl)thiotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.4.1"^^xsd:string) "methyl coenzyme M reductase activity"^^xsd:string) AnnotationAssertion( "methyl-coenzyme-M reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cutinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.74"^^xsd:string) "cutin hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.74"^^xsd:string) Annotation( "MetaCyc:3.1.1.74-RXN"^^xsd:string) "Catalysis of the reaction: cutin + H2O = cutin monomers."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.75"^^xsd:string) "poly((R)-hydroxyalkanoic acid) depolymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.75"^^xsd:string) Annotation( "MetaCyc:3.1.1.75-RXN"^^xsd:string) "Catalysis of the reaction: H2O + poly[(R)-3-hydroxybutanoate](n) = poly[(R)-3-hydroxybutanoate](x) + poly[(R)-3-hydroxybutanoate](n-x); x is 1-5."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.75"^^xsd:string) "poly(HA(SCL)) depolymerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "poly(3-hydroxybutyrate) depolymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.75"^^xsd:string) "poly[(R)-3-hydroxybutyrate] hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.75"^^xsd:string) "poly[(R)-hydroxyalkanoic acid] depolymerase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.75"^^xsd:string) "poly(HA) depolymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.75"^^xsd:string) "PHB depolymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.75"^^xsd:string) "poly(HASCL) depolymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.75"^^xsd:string) "poly(3HB) depolymerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.76"^^xsd:string) "poly{oxycarbonyl[(R)-2-pentylethylene]} hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.76"^^xsd:string) "poly[(R)-3-hydroxyoctanoate] hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.76"^^xsd:string) "PHO depolymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.76"^^xsd:string) "poly[(R)-hydroxyalkanoic acid] depolymerase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.76"^^xsd:string) Annotation( "MetaCyc:3.1.1.76-RXN"^^xsd:string) "Catalysis of the reaction: H2O + poly[(R)-3-hydroxyoctanoate](n) = poly[(R)-3-hydroxyoctanoate](x) + poly[(R)-3-hydroxyoctanoate](n-x); x is 1-5."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.76"^^xsd:string) "PHA depolymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.76"^^xsd:string) "poly((R)-3-hydroxyoctanoate) hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.76"^^xsd:string) "poly((R)-hydroxyalkanoic acid) depolymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.76"^^xsd:string) "poly(HA(MCL)) depolymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.76"^^xsd:string) "poly(3HO) depolymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.76"^^xsd:string) "poly(HA) depolymerase activity"^^xsd:string) AnnotationAssertion(rdfs:label "poly(3-hydroxyoctanoate) depolymerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.76"^^xsd:string) "poly(HAMCL) depolymerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.77"^^xsd:string) Annotation( "MetaCyc:3.1.1.77-RXN"^^xsd:string) "Catalysis of the reaction: 3-(acyloxy)acyl group of bacterial toxin = 3-hydroxyacyl group of bacterial toxin + a fatty acid."^^xsd:string) AnnotationAssertion(rdfs:label "acyloxyacyl hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.78"^^xsd:string) "polyneuridine aldehyde esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.78"^^xsd:string) "polyneuridine aldehyde hydrolase (decarboxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "polyneuridine-aldehyde esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.78"^^xsd:string) Annotation( "RHEA:17504"^^xsd:string) "Catalysis of the reaction: H(2)O + polyneuridine aldehyde = 16-epivellosimine + CO(2) + methanol."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.78"^^xsd:string) "PNAE activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.69"^^xsd:string) Annotation( "RHEA:22655"^^xsd:string) "Catalysis of the reaction: 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + H(2)O = 2-O-(beta-D-glucosyl)-sn-glycerol + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "glucosylglycerol 3-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.69"^^xsd:string) "salt tolerance protein A"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.69"^^xsd:string) "2-(beta-D-glucosyl)-sn-glycerol-3-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.69"^^xsd:string) "StpA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.70"^^xsd:string) "alpha-D-mannosyl-3-phosphoglycerate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannosyl-3-phosphoglycerate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.70"^^xsd:string) Annotation( "RHEA:19312"^^xsd:string) "Catalysis of the reaction: 2-(alpha-D-mannosyl)-3-phosphoglycerate + H(2)O = 2-(alpha-D-mannosyl)-D-glycerate + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.71"^^xsd:string) "(R)-2-phospho-3-sulfolactate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-phosphosulfolactate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.71"^^xsd:string) Annotation( "RHEA:23419"^^xsd:string) "Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate + H(2)O = (R)-3-sulfolactate + phosphate."^^xsd:string) AnnotationAssertion( "2-phosphosulpholactate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.71"^^xsd:string) "(2R)-phosphosulfolactate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.71"^^xsd:string) "ComB phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5-phytase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.72"^^xsd:string) "myo-inositol-hexakisphosphate 5-phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.72"^^xsd:string) Annotation( "MetaCyc:3.1.3.72-RXN"^^xsd:string) "Catalysis of the reaction: H2O + myo-inositol hexakisphosphate = phosphate + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.144"^^xsd:string) "alpha-Kdo-ase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.144"^^xsd:string) Annotation( "MetaCyc:3.2.1.144-RXN"^^xsd:string) "Catalysis of the reaction: 3-deoxyoctulosonyl-lipopolysaccharide + H2O = 3-deoxyoctulosonic acid + lipopolysaccharide."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.144"^^xsd:string) "3-deoxyoctulosonyl-lipopolysaccharide hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-deoxyoctulosonase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-primeverosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.149"^^xsd:string) Annotation( "MetaCyc:3.2.1.149-RXN"^^xsd:string) "Catalysis of the reaction: a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside + H2O = 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose + an alcohol."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.149"^^xsd:string) "6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside 6-O-(beta-D-xylosyl)-beta-D-glucohydrolase activity"^^xsd:string) AnnotationAssertion( "b-primeverosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.85"^^xsd:string) "(S)-N-acetylphenylethylamine:H2O hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.85"^^xsd:string) "(S)-N-acetyl-1-phenylethylamine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.85"^^xsd:string) Annotation( "RHEA:23955"^^xsd:string) "Catalysis of the reaction: N-acetylphenylethylamine + H(2)O = acetate + phenylethylamine."^^xsd:string) AnnotationAssertion(rdfs:label "(S)-N-acetyl-1-phenylethylamine hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.86"^^xsd:string) "Pseudomonas mandelamide hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mandelamide amidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.86"^^xsd:string) "mandelamide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.86"^^xsd:string) Annotation( "RHEA:22879"^^xsd:string) "Catalysis of the reaction: (R)-mandelamide + H(2)O = (R)-mandelate + NH(4)(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-carbamoyl-L-amino-acid hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.87"^^xsd:string) Annotation( "MetaCyc:3.5.1.87-RXN"^^xsd:string) "Catalysis of the reaction: N-carbamoyl-L-2-amino acid + H2O = L-2-amino acid + NH3 + CO2. The N-carbamoyl-L-2-amino acid is a 2-ureido carboxylate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.87"^^xsd:string) "L-carbamoylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.87"^^xsd:string) "N-carbamoyl-L-amino acid amidohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.2.16"^^xsd:string) "cyclic imide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.16"^^xsd:string) "cyclic-imide amidohydrolase (decyclicizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.16"^^xsd:string) "imidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.16"^^xsd:string) "cyclic-imide amidohydrolase (decyclizing)"^^xsd:string) AnnotationAssertion(rdfs:label "maleimide hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.2.16"^^xsd:string) Annotation( "RHEA:24479"^^xsd:string) "Catalysis of the reaction: H(2)O + maleimide = H(+) + maleamate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.99.5"^^xsd:string) "2-aminomuconate aminohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-aminomuconate deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.99.5"^^xsd:string) Annotation( "RHEA:20999"^^xsd:string) "Catalysis of the reaction: 2-aminomuconate + H(2)O + H(+) = (Z)-5-oxohex-2-enedioate + NH(4)(+)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta,beta-carotene-9',10'-dioxygenase activity"^^xsd:string) AnnotationAssertion( "b,b-carotene-9',10'-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11278918"^^xsd:string) "Catalysis of the reaction: beta-carotene + O2 = beta-apo-10'-carotenal + beta-ionone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "icosanoid binding"^^xsd:string) AnnotationAssertion( "eicosanoid binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with icosanoids, any C20 polyunsaturated fatty acids or their derivatives, including the leukotrienes and the prostanoids."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "icosatetraenoic acid binding"^^xsd:string) AnnotationAssertion( "eicosatetraenoic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with icosatetraenoic acid, any straight-chain fatty acid with twenty carbon atoms and four double bonds per molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arachidonic acid binding"^^xsd:string) AnnotationAssertion( "arachidonate binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.79"^^xsd:string) "sulfopyruvate carboxy-lyase (2-sulfoacetaldehyde-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.79"^^xsd:string) "sulfopyruvate carboxy-lyase activity"^^xsd:string) AnnotationAssertion( "sulphopyruvate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.79"^^xsd:string) Annotation( "RHEA:20951"^^xsd:string) "Catalysis of the reaction: 3-sulfopyruvate + H(+) = CO(2) + sulfoacetaldehyde."^^xsd:string) AnnotationAssertion(rdfs:label "sulfopyruvate decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.1.80"^^xsd:string) Annotation( "RHEA:18700"^^xsd:string) "Catalysis of the reaction: (4-hydroxyphenyl)pyruvate + H(+) = (4-hydroxyphenyl)acetaldehyde + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.80"^^xsd:string) "4-hydroxyphenylpyruvate carboxy-lyase (4-hydroxyphenylacetaldehyde-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxyphenylpyruvate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.80"^^xsd:string) "4-hydroxyphenylpyruvate carboxy-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.41"^^xsd:string) Annotation( "RHEA:18728"^^xsd:string) "Catalysis of the reaction: 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA = acetyl-CoA + vanillin."^^xsd:string) AnnotationAssertion(rdfs:label "vanillin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.41"^^xsd:string) "3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propionyl-CoA:vanillin lyase (acetyl-CoA-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.41"^^xsd:string) "3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA vanillin-lyase (acetyl-CoA-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.101"^^xsd:string) Annotation( "MetaCyc:4.2.1.101-RXN"^^xsd:string) "Catalysis of the reaction: trans-feruloyl-CoA + H2O = 4-hydroxy-3-methoxyphenyl-beta-hydroxypropionyl-CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.101"^^xsd:string) "trans-feruloyl-CoA hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.101"^^xsd:string) "4-hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA hydro-lyase (trans-feruloyl-CoA-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "trans-feruloyl-CoA hydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.103"^^xsd:string) "N-cyclohexylformamide hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.103"^^xsd:string) "isonitrile hydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyclohexyl-isocyanide hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.103"^^xsd:string) Annotation( "RHEA:18200"^^xsd:string) "Catalysis of the reaction: N-cyclohexylformamide + H(+) = cyclohexyl isocyanide + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.103"^^xsd:string) "N-cyclohexylformamide hydro-lyase (cyclohexyl-isocyanide-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.14"^^xsd:string) Annotation( "MetaCyc:4.2.3.14-RXN"^^xsd:string) "Catalysis of the reaction: geranyl diphosphate = pinene + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.14"^^xsd:string) "beta-geraniolene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.14"^^xsd:string) "(-)-(1S,5S)-pinene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.14"^^xsd:string) "geranyl-diphosphate diphosphate-lyase (cyclizing, pinene-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.14"^^xsd:string) "geranyldiphosphate diphosphate lyase (pinene forming)"^^xsd:string) AnnotationAssertion(rdfs:label "pinene synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "geranyl-diphosphate diphosphate-lyase (myrcene-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.15"^^xsd:string) Annotation( "RHEA:16968"^^xsd:string) "Catalysis of the reaction: geranyl diphosphate = diphosphate + myrcene."^^xsd:string) AnnotationAssertion(rdfs:label "myrcene synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.16"^^xsd:string) "geranyldiphosphate diphosphate lyase (limonene forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.16"^^xsd:string) Annotation( "MetaCyc:4.2.3.16-RXN"^^xsd:string) "Catalysis of the reaction: geranyl diphosphate = (4S)-limonene + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.16"^^xsd:string) "geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-(4S)-limonene-forming]"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.16"^^xsd:string) "geranyldiphosphate diphosphate lyase [cyclizing, (4S)-limonene-forming]"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.16"^^xsd:string) "4S-(-)-limonene synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(4S)-limonene synthase activity"^^xsd:string) AnnotationAssertion( "(-)-(4S)-limonene synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.17"^^xsd:string) Annotation( "RHEA:20915"^^xsd:string) "Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = diphosphate + taxa-4,11-diene."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.17"^^xsd:string) "taxa-4(5),11(12)-diene synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "taxadiene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.17"^^xsd:string) "geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxa-4,11-diene-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.17"^^xsd:string) "geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxadiene-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.18"^^xsd:string) "(+)-copalyl-diphosphate diphosphate-lyase (cyclizing, (-)-abietadiene-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.18"^^xsd:string) Annotation( "RHEA:13876"^^xsd:string) "Catalysis of the reaction: (+)-copalyl diphosphate = (-)-abietadiene + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.18"^^xsd:string) "copalyl-diphosphate diphosphate-lyase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.18"^^xsd:string) "abietadiene cyclase activity"^^xsd:string) AnnotationAssertion(rdfs:label "abietadiene synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-hydroxypropyl-CoM lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.23"^^xsd:string) "epoxyalkane:CoM transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.23"^^xsd:string) "epoxyalkane:2-mercaptoethanesulfonate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.23"^^xsd:string) "epoxypropane:coenzyme M transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.23"^^xsd:string) "epoxypropyl:CoM transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.23"^^xsd:string) "2-hydroxypropyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.23"^^xsd:string) "(R)-2-hydroxypropyl-CoM 2-mercaptoethanesulfonate lyase (cyclizing; epoxyalkane-ring-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.19"^^xsd:string) Annotation( "MetaCyc:4.2.99.19-RXN"^^xsd:string) "Catalysis of the reactions: (R)-2-hydroxypropyl-CoM = H-S-CoM + (R)-1,2-epoxypropane, and (S)-2-hydroxypropyl-CoM = H-S-CoM + (S)-1,2-epoxypropane."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.23"^^xsd:string) "coenzyme M-epoxyalkane ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.23"^^xsd:string) "(R)-[or (S)-]2-hydroxypropyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.23"^^xsd:string) "epoxyalkyl:CoM transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.23"^^xsd:string) "epoxyalkane:coenzyme M transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.23"^^xsd:string) "EaCoMT activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.3.3"^^xsd:string) "deacetylisoipecoside dopamine-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "deacetylisoipecoside synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.3.3"^^xsd:string) Annotation( "RHEA:21759"^^xsd:string) "Catalysis of the reaction: deacetylisoipecoside + H(2)O = dopamine + secologanin."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.3.3"^^xsd:string) "deacetylisoipecoside dopamine-lyase (secologanin-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.3.4"^^xsd:string) "deacetylipecoside dopamine-lyase (secologanin-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "deacetylipecoside synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.3.4"^^xsd:string) "deacetylipecoside dopamine-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.3.4"^^xsd:string) Annotation( "RHEA:12299"^^xsd:string) "Catalysis of the reaction: deacetylipecoside + H(2)O = dopamine + secologanin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "maltose epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.21"^^xsd:string) "maltose 1-epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.1.3.21"^^xsd:string) Annotation( "RHEA:21231"^^xsd:string) "Catalysis of the reaction: alpha-maltose = beta-maltose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.5.1.12"^^xsd:string) "(+)-copalyl-diphosphate lyase (decyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.5.1.12"^^xsd:string) Annotation( "RHEA:24319"^^xsd:string) "Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = (+)-copalyl diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "copalyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion( "diterpene cyclase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.23"^^xsd:string) "L-aspartate:tRNAAsx ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.23"^^xsd:string) Annotation( "MetaCyc:6.1.1.23-RXN"^^xsd:string) "Catalysis of the reaction: tRNA(Asx) + L-aspartate + ATP = aspartyl-tRNA(Asx) + diphosphate + AMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.23"^^xsd:string) "nondiscriminating aspartyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion( "aspartate-tRNAAsn ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aspartate-tRNA(Asn) ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.1.1.24"^^xsd:string) Annotation( "MetaCyc:6.1.1.24-RXN"^^xsd:string) "Catalysis of the reaction: tRNA(Glx) + L-glutamate + ATP = glutamyl-tRNA(Glx) + diphosphate + AMP."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.24"^^xsd:string) "nondiscriminating glutamyl-tRNA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.24"^^xsd:string) "L-glutamate:tRNAGlx ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "glutamate-tRNA(Gln) ligase activity"^^xsd:string) AnnotationAssertion( "glutamate-tRNAGln ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "lysine-tRNAPyl ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.25"^^xsd:string) "L-lysine:tRNAPyl ligase (AMP-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "lysine-tRNA(Pyl) ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.1.1.25"^^xsd:string) Annotation( "MetaCyc:6.1.1.25-RXN"^^xsd:string) "Catalysis of the reaction: tRNA(Pyl) + L-lysine + ATP = L-lysyl-tRNA(Pyl) + diphosphate + AMP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "trans-feruloyl-CoA synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.34"^^xsd:string) "trans-feruloyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.34"^^xsd:string) Annotation( "MetaCyc:6.2.1.34-RXN"^^xsd:string) "Catalysis of the reaction: ferulic acid + CoASH + ATP = trans-feruloyl-CoA + products of ATP breakdown."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.2.1.34"^^xsd:string) "trans-ferulate:CoASH ligase (ATP-hydrolysing)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.26"^^xsd:string) "ACV synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.26"^^xsd:string) "L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.26"^^xsd:string) "L-2-aminohexanedioate:L-cysteine:L-valine ligase (AMP-forming, valine-inverting)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.26"^^xsd:string) Annotation( "RHEA:23199"^^xsd:string) "Catalysis of the reaction: L-2-aminoadipate + L-cysteine + L-valine + 3 ATP + H(2)O = N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate + 6 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.26"^^xsd:string) "L-alpha-aminoadipyl-cysteinyl-valine synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.27"^^xsd:string) Annotation( "RHEA:11763"^^xsd:string) "Catalysis of the reaction: 2 N(6)-acetyl-N(6)-hydroxy-L-lysine + 4 ATP + citrate + 2 H(2)O = 4 ADP + aerobactin + 8 H(+) + 4 phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "aerobactin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.27"^^xsd:string) "citrate:6-N-acetyl-6-N-hydroxy-L-lysine ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.27"^^xsd:string) "citrate:N6-acetyl-N6-hydroxy-L-lysine ligase (ADP-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.5.6"^^xsd:string) "asparaginyl-tRNA synthase (glutamine-hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.6"^^xsd:string) "Asp-AdT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.6"^^xsd:string) "aspartyl-tRNAAsn:L-glutamine amido-ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.6"^^xsd:string) "aspartyl-tRNAAsn amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.6"^^xsd:string) Annotation( "MetaCyc:6.3.5.6-RXN"^^xsd:string) "Catalysis of the reaction: L-glutamine + aspartyl-tRNA(Asn) + ATP = L-glutamate + asparaginyl-tRNA(Asn) + phosphate + ADP."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.6"^^xsd:string) "Asp-tRNAAsn:L-glutamine amido-ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.6"^^xsd:string) "Asp-tRNA(Asn) amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.6"^^xsd:string) "Asp-tRNAAsn amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.6"^^xsd:string) "aspartyl-tRNA(Asn) amidotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.7"^^xsd:string) "Glu-tRNAGln amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.-"^^xsd:string) "Glu-AdT activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.7"^^xsd:string) "Glu-tRNAGln:L-glutamine amido-ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.7"^^xsd:string) "glutamyl-tRNAGln amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.7"^^xsd:string) "glutaminyl-tRNA synthase (glutamine-hydrolysing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.7"^^xsd:string) Annotation( "MetaCyc:6.3.5.7-RXN"^^xsd:string) "Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP."^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.-"^^xsd:string) "glutamyl-tRNA(Gln) amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.-"^^xsd:string) "Glu-tRNA(Gln) amidotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.7"^^xsd:string) "glutamyl-tRNAGln:L-glutamine amido-ligase (ADP-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.44"^^xsd:string) "protein-L-glutamine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.44"^^xsd:string) "glutaminylpeptide glutaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.44"^^xsd:string) "peptidylglutaminase II"^^xsd:string) AnnotationAssertion(rdfs:label "protein-glutamine glutaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.44"^^xsd:string) "glutaminyl-peptide glutaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.44"^^xsd:string) "destabilase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.44"^^xsd:string) Annotation( "MetaCyc:CHEBDEAMID-RXN"^^xsd:string) "Catalysis of the reaction: protein L-glutamine + H2O = protein L-glutamate + NH3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.5.1.44"^^xsd:string) "peptidoglutaminase II activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.21"^^xsd:string) Annotation( "RHEA:20004"^^xsd:string) "Catalysis of the reaction: glycolaldehyde + H(2)O + NAD(+) = glycolate + 2 H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.21"^^xsd:string) "glycolaldehyde:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycolaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.21"^^xsd:string) "glycol aldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.262"^^xsd:string) "4-(phosphonooxy)-L-threonine:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.262"^^xsd:string) Annotation( "MetaCyc:1.1.1.262-RXN"^^xsd:string) "Catalysis of the reaction: 4-(phosphonooxy)-threonine + NAD+ = 2-amino-3-oxo-4-phosphonooxybutyrate + NADH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxythreonine-4-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.262"^^xsd:string) "L-threonine 4-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.262"^^xsd:string) "NAD+-dependent threonine 4-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.262"^^xsd:string) "4-(phosphohydroxy)-L-threonine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.262"^^xsd:string) "NAD(+)-dependent threonine 4-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.262"^^xsd:string) "PdxA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.263"^^xsd:string) "AF reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1,5-anhydro-D-fructose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.263"^^xsd:string) "1,5-anhydro-D-glucitol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.263"^^xsd:string) Annotation( "RHEA:20668"^^xsd:string) "Catalysis of the reaction: 1,5-anhydro-D-glucitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.264"^^xsd:string) Annotation( "MetaCyc:1.1.1.264-RXN"^^xsd:string) "Catalysis of the reaction: L-idonate + NAD(P)+ = 5-dehydrogluconate + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(rdfs:label "L-idonate 5-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.264"^^xsd:string) "L-idonate:NAD(P)+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dTDP-4-dehydro-6-deoxyglucose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.266"^^xsd:string) "dTDP-4-keto-6-deoxyglucose reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.266"^^xsd:string) "dTDP-D-fucose:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.266"^^xsd:string) Annotation( "RHEA:21903"^^xsd:string) "Catalysis of the reaction: dTDP-D-fucose + NADP(+) = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADPH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.268"^^xsd:string) "2-[2-(R)-hydroxypropylthio]ethanesulfonate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-(R)-hydroxypropyl-CoM dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.268"^^xsd:string) "2-(2-(R)-hydroxypropylthio)ethanesulfonate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.268"^^xsd:string) Annotation( "RHEA:13252"^^xsd:string) "Catalysis of the reaction: 2-(R)-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-(S)-hydroxypropyl-CoM dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.269"^^xsd:string) Annotation( "RHEA:21055"^^xsd:string) "Catalysis of the reaction: 2-(S)-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + NADH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.269"^^xsd:string) "2-[2-(S)-hydroxypropylthio]ethanesulfonate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.269"^^xsd:string) "2-(2-(S)-hydroxypropylthio)ethanesulfonate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.271"^^xsd:string) Annotation( "MetaCyc:1.1.1.271-RXN"^^xsd:string) "Catalysis of the reaction: GDP-L-fucose + NAD+ = GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.271"^^xsd:string) "GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.271"^^xsd:string) "GDP-fucose synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "GDP-L-fucose synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.271"^^xsd:string) "GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.272"^^xsd:string) "(R)-sulfolactate:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.272"^^xsd:string) "L-sulfolactate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.272"^^xsd:string) "(R)-sulfolactate:NAD(P)(+) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.272"^^xsd:string) "(R)-2-hydroxyacid:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(R)-2-hydroxyacid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.272"^^xsd:string) Annotation( "MetaCyc:1.1.1.272-RXN"^^xsd:string) "Catalysis of the reaction: (S)-3-sulfolactate + NAD(P)+ = 3-sulfopyruvate + NAD(P)H + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.273"^^xsd:string) Annotation( "RHEA:20032"^^xsd:string) "Catalysis of the reaction: 10-deoxysarpagine + NADP(+) = H(+) + NADPH + vellosimine."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.273"^^xsd:string) "10-deoxysarpagine:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "vellosimine dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.274"^^xsd:string) "2,5-diketo-D-gluconate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.274"^^xsd:string) "YqhE reductase"^^xsd:string) AnnotationAssertion(rdfs:label "2,5-didehydrogluconate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.274"^^xsd:string) Annotation( "MetaCyc:1.1.1.274-RXN"^^xsd:string) "Catalysis of the reaction: 2-dehydro-D-gluconate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.274"^^xsd:string) "2-dehydro-D-gluconate:NADP+ 2-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.40"^^xsd:string) "D-arabitol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.40"^^xsd:string) "mannitol oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-mannitol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.40"^^xsd:string) "mannitol:oxygen oxidoreductase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.40"^^xsd:string) Annotation( "MetaCyc:1.1.3.40-RXN"^^xsd:string) "Catalysis of the reaction: mannitol + O2 = mannose + H2O2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.40"^^xsd:string) "D-arabinitol oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.41"^^xsd:string) "xylitol:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "xylitol oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.41"^^xsd:string) Annotation( "MetaCyc:1.1.3.41-RXN"^^xsd:string) "Catalysis of the reaction: xylitol + O2 = xylose + H2O2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.12.1.3"^^xsd:string) "hydrogen:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.1.3"^^xsd:string) "NADP-reducing hydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydrogen dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.1.3"^^xsd:string) "NADP-linked hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.1.3"^^xsd:string) Annotation( "MetaCyc:1.12.1.3-RXN"^^xsd:string) "Catalysis of the reaction: NADP+ + H2 = NADPH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.45"^^xsd:string) "linoleate:oxygen 11S-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.45"^^xsd:string) "manganese lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.45"^^xsd:string) Annotation( "RHEA:18996"^^xsd:string) "Catalysis of the reaction: linoleate + O(2) = (9Z,11S,12Z)-11-hydroperoxyoctadeca-9,12-dienoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.45"^^xsd:string) "linoleate dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "linoleate 11-lipoxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.46"^^xsd:string) "4-hydroxyphenylpyruvate dioxygenase II activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxymandelate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.46"^^xsd:string) "4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.46"^^xsd:string) Annotation( "MetaCyc:1.13.11.46-RXN"^^xsd:string) "Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = 4-hydroxymandelate + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3-hydroxy-2-methyl-quinolin-4-one 2,4-dioxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.48"^^xsd:string) "(1H)-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase activity"^^xsd:string) AnnotationAssertion( "1H-3-hydroxy-4-oxo quinaldine 2,4-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.48"^^xsd:string) "3-hydroxy-2-methyl-1H-quinolin-4-one 2,4-dioxygenase (CO-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.48"^^xsd:string) Annotation( "RHEA:21575"^^xsd:string) "Catalysis of the reaction: 3-hydroxy-2-methylquinolin-4(1H)-one + H(+) + O(2) = N-acetylanthranilate + CO."^^xsd:string) AnnotationAssertion( "1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.49"^^xsd:string) "chlorite dismutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.49"^^xsd:string) Annotation( "RHEA:21407"^^xsd:string) "Catalysis of the reaction: chloride + O(2) = chlorite."^^xsd:string) AnnotationAssertion(rdfs:label "chlorite O2-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.49"^^xsd:string) "chloride:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.12.12"^^xsd:string) "8'-apo-beta-carotenol:O2 oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "apo-beta-carotenoid-14',13'-dioxygenase activity"^^xsd:string) AnnotationAssertion( "apo-b-carotenoid-14',13'-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.12"^^xsd:string) Annotation( "RHEA:26026"^^xsd:string) "Catalysis of the reaction: 8'-apo-beta-carotenol + O(2) = (E,E)-7-hydroxy-6-methylhepta-3,5-dienal + 14'-apo-beta-carotenal."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.19"^^xsd:string) Annotation( "MetaCyc:1.14.11.19-RXN"^^xsd:string) "Catalysis of the reaction: leucocyanidin + 2-oxoglutarate + O2 = cis- or trans-dihydroquercetin + succinate + CO2 + 2 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.19"^^xsd:string) "leucoanthocyanidin dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.19"^^xsd:string) "anthocyanidin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.19"^^xsd:string) "leucoanthocyanidin hydroxylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.19"^^xsd:string) "leucocyanidin,2-oxoglutarate:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "leucocyanidin oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.20"^^xsd:string) "desacetyoxyvindoline-17-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.20"^^xsd:string) "desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4-beta-hydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.20"^^xsd:string) "desacetoxyvindoline-4-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.20"^^xsd:string) "deacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4beta-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.20"^^xsd:string) "desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4beta-hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "desacetoxyvindoline 4-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.20"^^xsd:string) "D17H activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.20"^^xsd:string) Annotation( "MetaCyc:1.14.11.20-RXN"^^xsd:string) "Catalysis of the reaction: desacetoxyvindoline + 2-oxoglutarate + O2 = desacetylvindoline + succinate + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "quinine 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.67"^^xsd:string) Annotation( "RHEA:20152"^^xsd:string) "Catalysis of the reaction: H(+) + NADPH + O(2) + quinine = 3-hydroxyquinine + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.67"^^xsd:string) "quinine,NADPH:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.67"^^xsd:string) "nifedipine oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "quinine 3-monooxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.68"^^xsd:string) "(Z)-4-hydroxyphenylacetaldehyde oxime,NADPH:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.68"^^xsd:string) "cytochrome P450-II-dependent monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxyphenylacetaldehyde oxime monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.68"^^xsd:string) "4-hydroxybenzeneacetaldehyde oxime monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.68"^^xsd:string) "CYP71E1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.68"^^xsd:string) Annotation( "RHEA:18404"^^xsd:string) "Catalysis of the reaction: (Z)-(4-hydroxyphenyl)acetaldehyde oxime + H(+) + NADPH + O(2) = (S)-4-hydroxymandelonitrile + 2 H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.68"^^xsd:string) "4-hydroxyphenylacetaldehyde oxime,NADPH:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.68"^^xsd:string) "cytochrome P450II-dependent monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.68"^^xsd:string) "NADPH-cytochrome P450 reductase (CYP71E1)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.71"^^xsd:string) Annotation( "RHEA:16652"^^xsd:string) "Catalysis of the reaction: (S)-N-methylcoclaurine + H(+) + NADPH + O(2) = (S)-3'-hydroxy-N-methylcoclaurine + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.71"^^xsd:string) "cytochrome P450 80B1 activity"^^xsd:string) AnnotationAssertion( "N-methylcoclaurine 3'-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N-methylcoclaurine 3'-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.71"^^xsd:string) "(S)-N-methylcoclaurine,NADPH:oxygen oxidoreductase (3'-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.71"^^xsd:string) "(S)-N-methylcoclaurine 3'-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tabersonine 16-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.73"^^xsd:string) "tabersonine,NADPH:oxygen oxidoreductase (16-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.73"^^xsd:string) Annotation( "RHEA:14136"^^xsd:string) "Catalysis of the reaction: H(+) + NADPH + O(2) + tabersonine = 16-hydroxytabersonine + H(2)O + NADP(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "7-deoxyloganin 7-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.74"^^xsd:string) Annotation( "MetaCyc:1.14.13.74-RXN"^^xsd:string) "Catalysis of the reaction: 7-deoxyloganin + NADPH + H+ + O2 = loganin + NADP+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.74"^^xsd:string) "7-deoxyloganin,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.75"^^xsd:string) "vinorine,NADPH:oxygen oxidoreductase (21alpha-hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "vinorine hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.75"^^xsd:string) Annotation( "RHEA:17260"^^xsd:string) "Catalysis of the reaction: H(+) + NADPH + O(2) + vinorine = H(2)O + NADP(+) + vomilenine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.76"^^xsd:string) "5-alpha-taxadienol-10-beta-hydroxylase activity"^^xsd:string) AnnotationAssertion( "taxane 10b-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "taxane 10-beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.76"^^xsd:string) "taxa-4(20),11-dien-5alpha-yl acetate,NADPH:oxygen oxidoreductase (10beta-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.76"^^xsd:string) "taxane 10beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.76"^^xsd:string) Annotation( "RHEA:15244"^^xsd:string) "Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-yl acetate = 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H(2)O + NADP(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.77"^^xsd:string) "taxane 13alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion( "taxane 13a-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.77"^^xsd:string) Annotation( "RHEA:18952"^^xsd:string) "Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-ol = H(2)O + NADP(+) + taxa-4(20),11-dien-5alpha,13alpha-diol."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.77"^^xsd:string) "taxa-4(20),11-dien-5alpha-ol,NADPH:oxygen oxidoreductase (13alpha-hydroxylating)"^^xsd:string) AnnotationAssertion(rdfs:label "taxane 13-alpha-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.20.1"^^xsd:string) "DAOC synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.20.1"^^xsd:string) "DAOCS activity"^^xsd:string) AnnotationAssertion( "expandase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.20.1"^^xsd:string) "penicillin N expandase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.20.1"^^xsd:string) "penicillin-N,2-oxoglutarate:oxygen oxidoreductase (ring-expanding)"^^xsd:string) AnnotationAssertion(rdfs:label "deacetoxycephalosporin-C synthase activity"^^xsd:string) AnnotationAssertion( "deacetoxycephalosporin C synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.20.1"^^xsd:string) Annotation( "RHEA:20751"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + O(2) + penicillin N = CO(2) + deacetoxycephalosporin C + H(2)O + succinate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.31"^^xsd:string) "n-tetradecanoyl-CoA,NADPH:O2 oxidoreductase [11-(E) desaturating]"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.31"^^xsd:string) Annotation( "MetaCyc:1.14.99.31-RXN"^^xsd:string) "Catalysis of the reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (E)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O."^^xsd:string) AnnotationAssertion(rdfs:label "myristoyl-CoA 11-(E) desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.31"^^xsd:string) "n-tetradecanoyl-CoA,NAD(P)H:O2 oxidoreductase [11-(E) desaturating]"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.32"^^xsd:string) "n-tetradecanoyl-CoA,NAD(P)H:O2 oxidoreductase [11-(Z) desaturating]"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.32"^^xsd:string) Annotation( "MetaCyc:1.14.99.32-RXN"^^xsd:string) "Catalysis of the reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (Z)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.32"^^xsd:string) "n-tetradecanoyl-CoA,NADPH:O2 oxidoreductase [11-(Z) desaturating]"^^xsd:string) AnnotationAssertion(rdfs:label "myristoyl-CoA 11-(Z) desaturase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.34"^^xsd:string) Annotation( "MetaCyc:1.14.99.34-RXN"^^xsd:string) "Catalysis of the reaction: O2 + NADPH + H+ + 7-O-methylluteone = H2O + NADP+ + dihydrofurano derivatives."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.34"^^xsd:string) "monoprenyl isoflavone monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.34"^^xsd:string) "7-O-methylluteone,NADPH:O2 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.34"^^xsd:string) "7-O-methylluteone:O2 oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "monoprenyl isoflavone epoxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.99.35"^^xsd:string) "thiophene-2-carbonyl-CoA, hydrogen-donor:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.35"^^xsd:string) "thiophene-2-carboxyl-CoA monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.35"^^xsd:string) "thiophene-2-carboxyl-CoA hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.35"^^xsd:string) Annotation( "RHEA:18932"^^xsd:string) "Catalysis of the reaction: AH(2) + O(2) + thiophene-2-carbonyl-CoA = 5-hydroxythiophene-2-carbonyl-CoA + A + H(2)O + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.35"^^xsd:string) "thiophene-2-carboxyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "thiophene-2-carbonyl-CoA monooxygenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "taxadiene 5-alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.37"^^xsd:string) Annotation( "RHEA:14052"^^xsd:string) "Catalysis of the reaction: AH(2) + O(2) + taxa-4,11-diene = A + H(2)O + taxa-4(20),11-dien-5alpha-ol."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.37"^^xsd:string) "taxa-4,11-diene,hydrogen-donor:oxygen oxidoreductase (5alpha-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.99.37"^^xsd:string) "taxadiene 5alpha-hydroxylase activity"^^xsd:string) AnnotationAssertion( "taxadiene 5a-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.15.1.2"^^xsd:string) "neelaredoxin activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.2"^^xsd:string) "rubredoxin:superoxide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.2"^^xsd:string) "desulfoferrodoxin activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.15.1.2"^^xsd:string) Annotation( "MetaCyc:1.15.1.2-RXN"^^xsd:string) "Catalysis of the reaction: superoxide + reduced rubredoxin + 2 H+ = H2O2 + rubredoxin."^^xsd:string) AnnotationAssertion(rdfs:label "superoxide reductase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.312"^^xsd:string) "4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:29590"^^xsd:string) "Catalysis of the reaction: 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal + NADP(+) = 2-oxo-2H-pyran-4,6-dicarboxylate + H(+) + NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "4-carboxy-2-hydroxymuconate semialdehyde hemiacetal dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.312"^^xsd:string) "alpha-hydroxy-gamma-carboxymuconic epsilon-semialdehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.312"^^xsd:string) "4-carboxy-2-hydroxy-cis,cis-muconate-6-semialdehyde:NADP(+) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.312"^^xsd:string) "2-hydroxy-4-carboxymuconate 6-semialdehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mycothiol-dependent formaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.66"^^xsd:string) Annotation( "MetaCyc:1.2.1.66-RXN"^^xsd:string) "Catalysis of the reaction: formaldehyde + mycothiol + NAD+ = S-formylmycothiol + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.66"^^xsd:string) "NAD/factor-dependent formaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.66"^^xsd:string) "formaldehyde:NAD+ oxidoreductase (mycothiol-formylating)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.1.67"^^xsd:string) "vanillin:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.67"^^xsd:string) Annotation( "RHEA:13312"^^xsd:string) "Catalysis of the reaction: H(2)O + NAD(+) + vanillin = 2 H(+) + NADH + vanillate."^^xsd:string) AnnotationAssertion(rdfs:label "vanillin dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.20.1.1"^^xsd:string) "phosphonate:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.20.1.1"^^xsd:string) Annotation( "RHEA:13176"^^xsd:string) "Catalysis of the reaction: H(2)O + NAD(+) + phosphonate = 2 H(+) + NADH + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.20.1.1"^^xsd:string) "NAD:phosphite oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.20.1.1"^^xsd:string) "NAD-dependent phosphite dehydrogenas activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.20.1.1"^^xsd:string) "phosphite dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphonate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.20.4.2"^^xsd:string) "gluthathione:methylarsonate oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methylarsonate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.20.4.2"^^xsd:string) Annotation( "RHEA:15972"^^xsd:string) "Catalysis of the reaction: 2 glutathione + H(+) + methylarsonate = glutathione disulfide + H(2)O + methylarsonous acid."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.20.4.2"^^xsd:string) "MMA(V) reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.20.9.1"^^xsd:string) "arsenite:azurin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.20.9.1"^^xsd:string) Annotation( "MetaCyc:1.20.98.1-RXN"^^xsd:string) "Catalysis of the reaction: H(2)O + arsenite + 2 oxidized azurin = 2 H(+) + 2 reduced azurin + arsenate."^^xsd:string) AnnotationAssertion(rdfs:label "arsenate reductase (azurin) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.20.9.1"^^xsd:string) "arsenite oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.20.99.1"^^xsd:string) "arsenate:(acceptor) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.20.99.1"^^xsd:string) "arsenate:acceptor oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arsenate reductase (donor) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.20.99.1"^^xsd:string) Annotation( "RHEA:18452"^^xsd:string) "Catalysis of the reaction: A + arsenite + H(2)O = AH(2) + arsenate + 2 H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.70"^^xsd:string) "4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP+ delta14-oxidoreductase activity"^^xsd:string) AnnotationAssertion( "D14-sterol reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.70"^^xsd:string) Annotation( "MetaCyc:1.3.1.70-RXN"^^xsd:string) "Catalysis of the reaction: NADP+ + 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol = NADPH + H+ + 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.70"^^xsd:string) "sterol C14-reductase activity"^^xsd:string) AnnotationAssertion( "sterol C-14 reductase activity"^^xsd:string) AnnotationAssertion( "C-14 sterol reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "delta14-sterol reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "delta24-sterol reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.72"^^xsd:string) "lanosterol delta24-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.72"^^xsd:string) "lanosterol Delta(24)-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.72"^^xsd:string) Annotation( "MetaCyc:1.3.1.72-RXN"^^xsd:string) "Catalysis of the reaction: NADP+ + 5-alpha-cholest-7-en-3-beta-ol = NADPH + H+ + 5-alpha-cholesta-7,24-dien-3-beta-ol."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.72"^^xsd:string) "sterol:NADP+ delta24-oxidoreductase activity"^^xsd:string) AnnotationAssertion( "D24-sterol reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.73"^^xsd:string) Annotation( "RHEA:12323"^^xsd:string) "Catalysis of the reaction: 17-O-acetylnorajmaline + NADP(+) = 1,2-dihydrovomilenine + H(+) + NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.73"^^xsd:string) "17-O-acetylnorajmaline:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1,2-dihydrovomilenine reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "secologanin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.9"^^xsd:string) "loganin:oxygen oxidoreductase (ring-cleaving)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.9"^^xsd:string) Annotation( "MetaCyc:1.3.3.9-RXN"^^xsd:string) "Catalysis of the reaction: loganin + NADPH + H+ + O2 = secologanin + NADP+ + 2 H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "15,16-dihydrobiliverdin:ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.2"^^xsd:string) Annotation( "MetaCyc:1.3.7.2-RXN"^^xsd:string) "Catalysis of the reaction: 15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.2"^^xsd:string) "PebA"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phycoerythrobilin:ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.3"^^xsd:string) "PebB"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.3"^^xsd:string) "(3Z)-phycoerythrobilin:ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.3"^^xsd:string) Annotation( "MetaCyc:1.3.7.3-RXN"^^xsd:string) "Catalysis of the reaction: (3Z)-phycoerythrobilin + oxidized ferredoxin = 15,16-dihydrobiliverdin + reduced ferredoxin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.7.4"^^xsd:string) "PFB synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.4"^^xsd:string) Annotation( "MetaCyc:1.3.7.4-RXN"^^xsd:string) "Catalysis of the reaction: (3Z)-phytochromobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.4"^^xsd:string) "P-Phi-B synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.4"^^xsd:string) "phytochromobilin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.4"^^xsd:string) "HY2"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.4"^^xsd:string) "(3Z)-phytochromobilin:ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phytochromobilin:ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.4"^^xsd:string) "PPhiB synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phycocyanobilin:ferredoxin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.5"^^xsd:string) Annotation( "MetaCyc:1.3.7.5-RXN"^^xsd:string) "Catalysis of the reaction: (3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.7.5"^^xsd:string) "(3Z)-phycocyanobilin:ferredoxin oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.3.10"^^xsd:string) "L-tryptophan alpha,beta-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.10"^^xsd:string) "L-tryptophan 2',3'-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.10"^^xsd:string) Annotation( "RHEA:19904"^^xsd:string) "Catalysis of the reaction: L-tryptophan + O(2) = alpha,beta-didehydrotryptophan + H(2)O(2) + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "tryptophan alpha,beta-oxidase activity"^^xsd:string) AnnotationAssertion( "tryptophan a,b-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.10"^^xsd:string) "L-tryptophan:oxygen alpha,beta-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.99.5"^^xsd:string) "glycine:acceptor oxidoreductase (hydrogen-cyanide-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.99.5"^^xsd:string) Annotation( "MetaCyc:1.4.99.5-RXN"^^xsd:string) "Catalysis of the reaction: glycine + 2 A = HCN + CO2 + 2 AH2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.99.5"^^xsd:string) "HCN synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glycine dehydrogenase (cyanide-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.99.5"^^xsd:string) "hydrogen cyanide synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.31"^^xsd:string) Annotation( "RHEA:21271"^^xsd:string) "Catalysis of the reaction: (R)-canadine + 2 NADP(+) = berberine + H(+) + 2 NADPH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.31"^^xsd:string) "(R)-tetrahydroberberine:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.31"^^xsd:string) "(R)-canadine synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "berberine reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.32"^^xsd:string) Annotation( "RHEA:16412"^^xsd:string) "Catalysis of the reaction: 1,2-dihydrovomilenine + NADP(+) = H(+) + NADPH + vomilenine."^^xsd:string) AnnotationAssertion(rdfs:label "vomilenine reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.32"^^xsd:string) "1,2-dihydrovomilenine:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.6.5.7"^^xsd:string) "NADH:2-hydroxy-1,4-benzoquinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.7"^^xsd:string) "2-hydroxy-1,4-benzoquinone:NADH oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.-"^^xsd:string) "hydroxybenzoquinone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.7"^^xsd:string) "1,2,4-trihydroxybenzene:NAD oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.7"^^xsd:string) "1,2,4-trihydroxybenzene:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxy-1,4-benzoquinone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.5.7"^^xsd:string) Annotation( "RHEA:12431"^^xsd:string) "Catalysis of the reaction: 2-hydroxy-1,4-benzoquinone + 2 H(+) + NADH = benzene-1,2,4-triol + NAD(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.2.3"^^xsd:string) "TOR activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.3"^^xsd:string) "trimethylamine:cytochrome c oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trimethylamine-N-oxide reductase (cytochrome c) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.3"^^xsd:string) Annotation( "MetaCyc:1.7.2.3-RXN"^^xsd:string) "Catalysis of the reaction: trimethylamine + 2 (ferricytochrome c)-subunit + H2O = trimethylamine-N-oxide + 2 (ferrocytochrome c)-subunit + 2 H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.2.3"^^xsd:string) "TMAO reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mycothione reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.15"^^xsd:string) "mycothiol:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.15"^^xsd:string) "mycothiol-disulfide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.15"^^xsd:string) Annotation( "MetaCyc:1.8.1.15-RXN"^^xsd:string) "Catalysis of the reaction: NAD(P)+ + mycothiol = NAD(P)H + H+ + mycothione."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.8.1.5"^^xsd:string) "NADPH:2-ketopropyl-coenzyme M oxidoreductase/carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.5"^^xsd:string) "2-mercaptoethanesulfonate,acetoacetate:NADP+ oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.5"^^xsd:string) Annotation( "RHEA:16980"^^xsd:string) "Catalysis of the reaction: acetoacetate + coenzyme M + NADP(+) = 2-oxopropyl-coenzyme M + CO(2) + NADPH."^^xsd:string) AnnotationAssertion(rdfs:label "2-oxopropyl-CoM reductase (carboxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.5"^^xsd:string) "NADPH:2-(2-ketopropylthio)ethanesulfonate oxidoreductase/carboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.1.5"^^xsd:string) "2-KPCC activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.97.1.8"^^xsd:string) "tetrachloroethene reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.8"^^xsd:string) "acceptor:trichloroethene oxidoreductase (chlorinating)"^^xsd:string) AnnotationAssertion(rdfs:label "tetrachloroethene reductive dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.97.1.8"^^xsd:string) Annotation( "MetaCyc:1.97.1.8-RXN"^^xsd:string) "Catalysis of the reaction: trichloroethene + chloride + acceptor = tetrachloroethene + reduced acceptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(iso)eugenol O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.146"^^xsd:string) "S-adenosyl-L-methionine:isoeugenol O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.146"^^xsd:string) Annotation( "MetaCyc:2.1.1.146-RXN"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + isoeugenol = S-adenosyl-L-homocysteine + isomethyleugenol."^^xsd:string) AnnotationAssertion( "isoeugenol O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.147"^^xsd:string) "S-adenosyl-L-methionine:protoberberine 13-C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.147"^^xsd:string) Annotation( "RHEA:14776"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + 2 NADPH + palmatine = S-adenosyl-L-homocysteine + corydaline + 2 NADP(+)."^^xsd:string) AnnotationAssertion(rdfs:label "corydaline synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.154"^^xsd:string) "oxopristanoyl-CoA thiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.154"^^xsd:string) "peroxisomal 3-oxoacyl coenzyme A thiolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.154"^^xsd:string) "peroxisome sterol carrier protein thiolase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.154"^^xsd:string) "4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA C2-4,8,12-trimethyltridecanoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.154"^^xsd:string) "sterol carrier protein"^^xsd:string) AnnotationAssertion( "propionyl-CoA C(2)-trimethyltridecanoyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "propionyl-CoA C2-trimethyltridecanoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.154"^^xsd:string) Annotation( "RHEA:10411"^^xsd:string) "Catalysis of the reaction: 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA."^^xsd:string) AnnotationAssertion( "sterol carrier protein X-related thiolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.154"^^xsd:string) "3-oxopristanoyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.154"^^xsd:string) "SCPx"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.154"^^xsd:string) "4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA 2-C-4,8,12-trimethyltridecanoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.154"^^xsd:string) "3-oxopristanoyl-CoA thiolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acetyl-CoA C-myristoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.155"^^xsd:string) "3-oxopalmitoyl-CoA-CoA acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.155"^^xsd:string) Annotation( "MetaCyc:2.3.1.155-RXN"^^xsd:string) "Catalysis of the reaction: myristoyl-CoA + acetyl-CoA = 3-oxopalmitoyl-CoA + CoA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.155"^^xsd:string) "myristoyl-CoA:acetyl-CoA C-myristoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.155"^^xsd:string) "myristoyl-CoA C-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.155"^^xsd:string) "3-oxopalmitoyl-CoA hydrolase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.156"^^xsd:string) Annotation( "MetaCyc:2.3.1.156-RXN"^^xsd:string) "Catalysis of the reaction: isovaleryl-CoA + 3 malonyl-CoA = 4 CoASH + 3 CO2 + 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.156"^^xsd:string) "3-methyl-1-(trihydroxyphenyl)butan-1-one synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phloroisovalerophenone synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.156"^^xsd:string) "isovaleryl-CoA:malonyl-CoA acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.156"^^xsd:string) "valerophenone synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.159"^^xsd:string) "malonyl-CoA:N-methylanthraniloyl-CoA malonyltransferase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.159"^^xsd:string) Annotation( "RHEA:22227"^^xsd:string) "Catalysis of the reaction: N-methylanthranilyl-CoA + 3 H(+) + 3 malonyl-CoA = 1,3-dihydroxy-N-methylacridone + 3 CO(2) + 4 CoA + H(2)O."^^xsd:string) AnnotationAssertion(rdfs:label "acridone synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "vinorine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.160"^^xsd:string) "acyl-CoA:16-epivellosimine O-acetyltransferase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.160"^^xsd:string) Annotation( "RHEA:24019"^^xsd:string) "Catalysis of the reaction: 16-epivellosimine + acetyl-CoA = CoA + vinorine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.161"^^xsd:string) "acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, thioester-hydrolysing)"^^xsd:string) AnnotationAssertion(rdfs:label "lovastatin nonaketide synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.161"^^xsd:string) Annotation( "RHEA:18568"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine(1+) + acetyl-CoA + 18 H(+) + 8 malonyl-CoA + 11 NADPH = S-adenosyl-L-homocysteine + 8 CO(2) + 9 CoA + dihydromonacolin L + 6 H(2)O + 11 NADP(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.162"^^xsd:string) "taxadienol acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.162"^^xsd:string) "acetyl coenzyme A: taxa-4(20),11(12)-dien-5alpha-ol O-acetyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.162"^^xsd:string) "taxa-4(20),11(12)-dien-5alpha-ol-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.162"^^xsd:string) "taxadien-5alpha-ol O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "taxadien-5-alpha-ol O-acetyltransferase activity"^^xsd:string) AnnotationAssertion( "taxadien-5a-ol O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.162"^^xsd:string) "acetyl coenzyme A:taxa-4(20),11(12)-dien-5-alpha-ol O-acetyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.162"^^xsd:string) Annotation( "RHEA:22031"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + taxa-4(20),11-dien-5alpha-ol = CoA + taxa-4(20),11-dien-5alpha-yl acetate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.162"^^xsd:string) "acetyl-CoA:taxa-4(20),11-dien-5alpha-ol O-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "10-hydroxytaxane O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.163"^^xsd:string) "acetyl coenzyme A:10-hydroxytaxane O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.163"^^xsd:string) Annotation( "RHEA:18840"^^xsd:string) "Catalysis of the reaction: 10-desacetyltaxuyunnanin C + acetyl-CoA = CoA + taxuyunnanin C."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.163"^^xsd:string) "acetyl-CoA:taxan-10beta-ol O-acetyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.163"^^xsd:string) "acetyl coenzyme A: 10-hydroxytaxane O-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "isopenicillin-N acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.164"^^xsd:string) "isopenicillin N:acyl-CoA acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.164"^^xsd:string) "acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.164"^^xsd:string) "acyl-coenzyme A:isopenicillin N acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.164"^^xsd:string) "acyl-CoA:isopenicillin N N-acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "isopenicillin-N N-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.164"^^xsd:string) Annotation( "MetaCyc:2.3.1.164-RXN"^^xsd:string) "Catalysis of the reaction: phenylacetyl-CoA + isopenicillin N + H2O = CoA + penicillin G + L-2-aminohexanedioate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.165"^^xsd:string) Annotation( "RHEA:12243"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + 3 H(+) + 3 malonyl-CoA + NADPH = 6-methylsalicylate + 3 CO(2) + 4 CoA + H(2)O + NADP(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.165"^^xsd:string) "acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl-reducing, thioester-hydrolysing and cyclizing)"^^xsd:string) AnnotationAssertion(rdfs:label "6-methylsalicylic acid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.165"^^xsd:string) "6-MSAS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.165"^^xsd:string) "MSAS activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.166"^^xsd:string) "benzoyl-CoA:taxan-2alpha-ol O-benzoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.166"^^xsd:string) "2alpha-hydroxytaxane 2-O-benzoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.166"^^xsd:string) "benzoyl-CoA:taxane 2-alpha-O-benzoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.166"^^xsd:string) Annotation( "RHEA:18744"^^xsd:string) "Catalysis of the reaction: 10-deacetyl-2-debenzoylbaccatin III + benzoyl-CoA = 10-deacetylbaccatin III + CoA."^^xsd:string) AnnotationAssertion( "2a-hydroxytaxane 2-O-benzoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.166"^^xsd:string) "2-debenzoyl-7,13-diacetylbaccatin III-2-O-benzoyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.166"^^xsd:string) "benzoyl-CoA:taxane 2alpha-O-benzoyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-alpha-hydroxytaxane 2-O-benzoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.167"^^xsd:string) "acetyl-CoA:taxan-10beta-ol O-acetyltransferase"^^xsd:string) AnnotationAssertion(rdfs:label "10-deacetylbaccatin III 10-O-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.167"^^xsd:string) Annotation( "RHEA:20140"^^xsd:string) "Catalysis of the reaction: 10-deacetylbaccatin III + acetyl-CoA = baccatin III + CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cis-p-coumarate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.209"^^xsd:string) Annotation( "RHEA:13132"^^xsd:string) "Catalysis of the reaction: cis-4-coumarate + UDP-D-glucose = 4'-O-beta-D-glucosyl-cis-4-coumarate + H(+) + UDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.209"^^xsd:string) "UDP-glucose:cis-p-coumarate beta-D-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.210"^^xsd:string) "uridine diphosphoglucose-limonoid glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.210"^^xsd:string) "limonoid UDP-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "limonoid glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.210"^^xsd:string) "LGTase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.210"^^xsd:string) "Catalysis of the reaction: UDP-glucose + limonin = glucosyl-limonin + UDP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds."^^xsd:string) AnnotationAssertion( "5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid binding"^^xsd:string) AnnotationAssertion(rdfs:label "5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid binding"^^xsd:string) AnnotationAssertion(rdfs:label "5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds."^^xsd:string) AnnotationAssertion(rdfs:label "5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding"^^xsd:string) AnnotationAssertion( "5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:11726664"^^xsd:string) "Catalysis of the reaction: testosterone + donor-H2 + O2 = 6-beta-hydroxytestosterone + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "testosterone 6-beta-hydroxylase activity"^^xsd:string) AnnotationAssertion( "testosterone 6b-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phosphoadenosine phosphosulfate binding"^^xsd:string) AnnotationAssertion(rdfs:label "3'-phosphoadenosine 5'-phosphosulfate binding"^^xsd:string) AnnotationAssertion( "3'-phosphoadenosine 5'-phosphosulphate binding"^^xsd:string) AnnotationAssertion( "PAPS binding"^^xsd:string) AnnotationAssertion( "adenosine 3'-phosphate 5'-phosphosulfate binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with 3'-phosphoadenosine 5'-phosphosulfate (PAPS), a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems."^^xsd:string) AnnotationAssertion( "3'-phosphoadenylyl-sulfate binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.8.2.33"^^xsd:string) "3'-phosphoadenylyl-sulfate:dermatan 6'-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.33"^^xsd:string) "Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate."^^xsd:string) AnnotationAssertion(rdfs:label "N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.33"^^xsd:string) "GalNAc4S-6ST"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.33"^^xsd:string) "N-acetylgalactosamine 4-sulfate 6-O-sulphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "flavin adenine dinucleotide binding"^^xsd:string) AnnotationAssertion( "FAD or FADH2 binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:24040"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:imk"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2."^^xsd:string) AnnotationAssertion( "flavine-adenine dinucleotide binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "NADP or NADPH binding"^^xsd:string) AnnotationAssertion(rdfs:label "NADP binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH."^^xsd:string) AnnotationAssertion( "nicotinamide adenine dinucleotide phosphate binding"^^xsd:string) AnnotationAssertion( "NADP+ or NADPH binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed."^^xsd:string) AnnotationAssertion(rdfs:label "coenzyme binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor"^^xsd:string) AnnotationAssertion( "oxidoreductase activity, acting on NADH or NADPH, oxygen as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.6.3.-"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an oxygen molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "AR binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with an androgen receptor."^^xsd:string) AnnotationAssertion(rdfs:label "androgen receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:9682036"^^xsd:string) "Interacting selectively and non-covalently with the AF-2 domain of a protein, a highly conserved ligand-dependent transactivation domain which is essential for receptor-mediated transcriptional activation."^^xsd:string) AnnotationAssertion(rdfs:label "AF-2 domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:9682036"^^xsd:string) "Interacting selectively and non-covalently with the AF-1 domain of a protein, a ligand-independent transactivation domain which is required for the full transcriptional activity of the receptor."^^xsd:string) AnnotationAssertion(rdfs:label "AF-1 domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DBD domain binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9682036"^^xsd:string) "Interacting selectively and non-covalently with the DBD, DNA binding domain, of a protein. The DNA binding domain of the vitamin D receptor, one of a family of receptors with the DBD, is split into three regions, the P, D and T boxes. Residues that are critical for target sequence selectivity form the P-box. The D-box contains residues that are important for homodimerization of class I nuclear receptors. The T-box is essential for both DNA-binding and transactivation of the VDR; this region may also be important for dimerization with RXR for class II nuclear receptors."^^xsd:string) AnnotationAssertion( "DNA binding domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ligand binding domain binding"^^xsd:string) AnnotationAssertion(rdfs:label "LBD domain binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9682036"^^xsd:string) "Interacting selectively and non-covalently with the LBD, the ligand binding domain found in nuclear receptors. In general, the LBDs consist of three layers comprised of twelve alpha-helices and several beta-strands that are organized around a lipophilic ligand-binding pocket."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:11323440"^^xsd:string) Annotation( "PMID:11356829"^^xsd:string) "Catalysis of the reaction: N-acetyllactosamine + 3'-phosphoadenosine 5'-phosphosulfate = 3-sulfo-N-acetyllactosamine + adenosine 3',5'-bisphosphate. N-acetyllactosamine residues are found in a number of different carbohydrate types. N-acetyllactosamine can also be written as Gal-beta-(1,4)-GlcNAc."^^xsd:string) AnnotationAssertion( "Gal-3-O-sulfotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "galactose 3-O-sulfotransferase activity"^^xsd:string) AnnotationAssertion( "galactose 3-O-sulphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "benzoylformate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.7"^^xsd:string) "benzoylformate carboxy-lyase activity"^^xsd:string) AnnotationAssertion( "phenylglyoxylate decarboxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.7"^^xsd:string) "benzoylformate carboxy-lyase (benzaldehyde-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.1.7"^^xsd:string) Annotation( "MetaCyc:BENZOYLFORMATE-DECARBOXYLASE-RXN"^^xsd:string) "Catalysis of the reaction: benzoylformate = benzaldehyde + CO2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1,1,2-trichloroethene reductive dehalogenase activity"^^xsd:string) AnnotationAssertion( "1,1,2-trichloroethylene reductive dehalogenase activity"^^xsd:string) AnnotationAssertion( "TCE-reductive dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:TCEREDCHLOR-RXN"^^xsd:string) Annotation( "UM-BBD_enzymeID:e0271"^^xsd:string) "Catalysis of the reaction: trichloroethene + 2 H+ + 2 e- = HCl + 1,2-dichloroethene."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "proteoglycan sulphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.-"^^xsd:string) Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + proteoglycan = adenosine 3',5'-bisphosphate + proteoglycan sulfate. A proteoglycan is a glycoprotein whose carbohydrate units are glycosaminoglycans."^^xsd:string) AnnotationAssertion( "proteoglycan sulfate transfer"^^xsd:string) AnnotationAssertion(rdfs:label "proteoglycan sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:14531730"^^xsd:string) "Interacting selectively and non-covalently with a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions."^^xsd:string) AnnotationAssertion(rdfs:label "WW domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CARD domain binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12054670"^^xsd:string) "Interacting selectively and non-covalently with a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing proteins that participate in activation or suppression of CARD carrying members of the caspase family."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11684676"^^xsd:string) Annotation( "PMID:12215544"^^xsd:string) "Interacting selectively and non-covalently with an RS domain of a protein; RS domains are usually highly phosphorylated and characterized by the presence of arginine (R)/serine (S) dipeptides. The RS domain promotes protein-protein interactions and directs subcellular localization and, in certain situations, nucleocytoplasmic shuttling of individual SR proteins. They also play a role in splicing."^^xsd:string) AnnotationAssertion(rdfs:label "RS domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a hydroxycinnamoyl group to an acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "hydroxycinnamoyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a malonyl group to a nitrogen atom on the acceptor molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "O-malonyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a malonyl group to an oxygen atom on the acceptor molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "O-hydroxycinnamoyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a hydroxycinnamoyl group to an oxygen atom on the acceptor molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a fructosyl group to an acceptor molecule, typically another carbohydrate or a lipid."^^xsd:string) AnnotationAssertion(rdfs:label "fructosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a low-density lipoprotein receptor."^^xsd:string) AnnotationAssertion(rdfs:label "low-density lipoprotein particle receptor binding"^^xsd:string) AnnotationAssertion( "LDL receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "low-density lipoprotein receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dopamine receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a dopamine receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2,4,6-trichlorophenol reductive dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:12697029"^^xsd:string) "Catalysis of the reaction: 2,4,6-trichlorophenol + 2 H+ + 2 e- = 2,4-dichlorophenol + HCl."^^xsd:string) AnnotationAssertion(rdfs:label "ortho-trichlorophenol reductive dehalogenase activity"^^xsd:string) AnnotationAssertion( "2,4,6-TCP reductive dehalogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "galactose uniporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "TC:2.A.1.1.6"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose (out) = galactose(in)."^^xsd:string) AnnotationAssertion( "galactose, glucose uniporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:21590515"^^xsd:string) "RAGE activity"^^xsd:string) AnnotationAssertion(rdfs:label "advanced glycation end-product receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:21590515"^^xsd:string) "AGE receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:12453678"^^xsd:string) Annotation( "PMID:12707408"^^xsd:string) Annotation( "PMID:7592757"^^xsd:string) Annotation( "PMID:9224812"^^xsd:string) Annotation( "Wikipedia:RAGE_(receptor)"^^xsd:string) "Combining with advanced glycation end-products and transmitting the signal to initiate a change in cell activity. Advanced glycation end-products (AGEs) form from a series of chemical reactions after an initial glycation event (a non-enzymatic reaction between reducing sugars and free amino groups of proteins)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the RAGE receptor, the receptor for advanced glycation end-products."^^xsd:string) AnnotationAssertion( "advanced glycation end-product receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "RAGE receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.148"^^xsd:string) "5,10-methylenetetrahydrofolate,FADH2:dUMP C-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.148"^^xsd:string) "FDTS activity"^^xsd:string) AnnotationAssertion(rdfs:label "thymidylate synthase (FAD) activity"^^xsd:string) AnnotationAssertion( "ThyX activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.148"^^xsd:string) "flavin dependent thymidylate synthase activity"^^xsd:string) AnnotationAssertion( "Thy1 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.148"^^xsd:string) "Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "diazepam binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with diazepam, one of the most widely used benzodiazepine drugs. It is used as an anti-anxiety-hypnotic agent and has the proprietary name Valium."^^xsd:string) AnnotationAssertion( "Valium binding"^^xsd:string) AnnotationAssertion( "diazepam binding inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor."^^xsd:string) AnnotationAssertion( "gamma-aminobutyric acid receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "GABA receptor binding"^^xsd:string) AnnotationAssertion( "4-aminobutanoate receptor binding"^^xsd:string) AnnotationAssertion( "4-aminobutyrate receptor binding"^^xsd:string) AnnotationAssertion( "diazepam binding inhibitor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phosphoserine/phosphothreonine binding"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoserine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a phosphorylated serine residue within a protein."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphothreonine binding"^^xsd:string) AnnotationAssertion( "phosphoserine/phosphothreonine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a phosphorylated threonine residue within a protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "water binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with water (H2O)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ice crystal binding"^^xsd:string) AnnotationAssertion( "ice nucleation inhibitor activity"^^xsd:string) AnnotationAssertion(rdfs:label "ice binding"^^xsd:string) AnnotationAssertion( "ice nucleation activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "Interacting selectively and non-covalently with ice, water reduced to the solid state by cold temperature. It is a white or transparent colorless substance, crystalline, brittle, and viscoidal."^^xsd:string) AnnotationAssertion( "antifreeze activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "pore-forming toxin activity"^^xsd:string) AnnotationAssertion( "cytotoxin activity"^^xsd:string) AnnotationAssertion(rdfs:label "toxin receptor binding"^^xsd:string) AnnotationAssertion( "exotoxin activity"^^xsd:string) AnnotationAssertion( "channel-forming toxin activity"^^xsd:string) AnnotationAssertion( "toxin activity"^^xsd:string) AnnotationAssertion( "endotoxin activity"^^xsd:string) AnnotationAssertion( "lipoprotein toxin"^^xsd:string) AnnotationAssertion( "neurotoxin activity"^^xsd:string) AnnotationAssertion( "enterotoxin activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a toxin receptor, a receptor for substances that cause injury to living organisms."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyruvate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of pyruvate, 2-oxopropanoate, from one side of the membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a cell adhesion molecule."^^xsd:string) AnnotationAssertion(rdfs:label "cell adhesion molecule binding"^^xsd:string) AnnotationAssertion( "CAM binding"^^xsd:string) AnnotationAssertion( "cell adhesion molecule activity"^^xsd:string) AnnotationAssertion( "adhesive extracellular matrix constituent"^^xsd:string) AnnotationAssertion( "cell adhesion receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "extracellular matrix constituent binding"^^xsd:string) AnnotationAssertion(rdfs:label "extracellular matrix binding"^^xsd:string) AnnotationAssertion( "adhesive extracellular matrix constituent"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a component of the extracellular matrix."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cobalt binding"^^xsd:string) AnnotationAssertion(rdfs:label "cobalt ion binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a cobalt (Co) ion."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "quaternary amine binding"^^xsd:string) AnnotationAssertion(rdfs:label "quaternary ammonium group binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a quaternary ammonium group, including glycine betaine, choline, carnitine and proline. A quaternary ammonium group is any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the enzyme nitric-oxide synthase."^^xsd:string) AnnotationAssertion(rdfs:label "nitric-oxide synthase binding"^^xsd:string) AnnotationAssertion( "NOS binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.6"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the joining of a metal ion to a molecule via a nitrogen-metal bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "ligase activity, forming nitrogen-metal bonds"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.6.1.-"^^xsd:string) "Catalysis of the ligation of two substances via a nitrogen-metal bond, forming a coordination complex."^^xsd:string) AnnotationAssertion(rdfs:label "ligase activity, forming nitrogen-metal bonds, forming coordination complexes"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.99.17"^^xsd:string) "Catalysis of the reaction: squalene = hop-22(29)-ene."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.17"^^xsd:string) "squalene mutase (cyclizing)"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18033581"^^xsd:string) "squalene:hopene cyclase activity"^^xsd:string) AnnotationAssertion(rdfs:label "squalene-hopene cyclase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Hsp27 protein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with Hsp27 proteins, a lightweight heat shock protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:ACETYLHOMOSER-CYS-RXN"^^xsd:string) Annotation( "RHEA:27825"^^xsd:string) "Catalysis of the reaction: O-acetyl-L-homoserine + hydrogen sulfide = homocysteine + acetate."^^xsd:string) AnnotationAssertion(rdfs:label "O-acetylhomoserine sulfhydrylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "microtubule plus-end binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:14557818"^^xsd:string) Annotation( "PMID:14614826"^^xsd:string) "Interacting selectively and non-covalently with the plus end of a microtubule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:14557818"^^xsd:string) Annotation( "PMID:14614826"^^xsd:string) "Interacting selectively and non-covalently with the minus end of a microtubule."^^xsd:string) AnnotationAssertion(rdfs:label "microtubule minus-end binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "actin filament binding"^^xsd:string) AnnotationAssertion( "F-actin binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits."^^xsd:string) AnnotationAssertion( "actin cross-linking activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "protein kinase A anchoring activity"^^xsd:string) AnnotationAssertion( "PKA binding"^^xsd:string) AnnotationAssertion(rdfs:label "protein kinase A binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with any subunit of protein kinase A."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "MAP-kinase anchoring activity"^^xsd:string) AnnotationAssertion( "MAP kinase binding"^^xsd:string) AnnotationAssertion( "MAPK binding"^^xsd:string) AnnotationAssertion(rdfs:label "mitogen-activated protein kinase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a mitogen-activated protein kinase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "GTPase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a GTPase, any enzyme that catalyzes the hydrolysis of GTP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a GDP-dissociation inhibitor protein."^^xsd:string) AnnotationAssertion( "GDI binding"^^xsd:string) AnnotationAssertion(rdfs:label "GDP-dissociation inhibitor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Rho GDI binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a Rho GDP-dissociation inhibitor protein."^^xsd:string) AnnotationAssertion(rdfs:label "Rho GDP-dissociation inhibitor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nucleic acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of RNA, ribonucleic acid, from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "RNA transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tRNA transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters."^^xsd:string) AnnotationAssertion(rdfs:label "NF-kappaB binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.41"^^xsd:string) "debranching enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.41"^^xsd:string) "R-enzyme"^^xsd:string) AnnotationAssertion( "amylopectin 6-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.41"^^xsd:string) "pullulan alpha-1,6-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pullulanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.41"^^xsd:string) "Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in pullulan (a linear polymer of alpha-(1,6)-linked maltotriose units) and in amylopectin and glycogen, and the a- and b-limit dextrins of amylopectin and glycogen."^^xsd:string) AnnotationAssertion( "pullulan 6-glucanohydrolase activity"^^xsd:string) AnnotationAssertion( "alpha-dextrin endo-1,6-alpha-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.41"^^xsd:string) "limit dextrinase (erroneous)"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.41"^^xsd:string) "bacterial debranching enzyme"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ADP reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:ADPREDUCT-RXN"^^xsd:string) "Catalysis of the reaction: dADP + thioredoxin disulfide + H2O = ADP + thioredoxin."^^xsd:string) AnnotationAssertion( "ADP reduction"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "UDP reduction"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:UDPREDUCT-RXN"^^xsd:string) "Catalysis of the reaction: dUDP + thioredoxin disulfide + H2O = UDP + thioredoxin."^^xsd:string) AnnotationAssertion(rdfs:label "UDP reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:CDPREDUCT-RXN"^^xsd:string) "Catalysis of the reaction: dCDP + thioredoxin disulfide + H2O = CDP + thioredoxin."^^xsd:string) AnnotationAssertion( "CDP reduction"^^xsd:string) AnnotationAssertion(rdfs:label "CDP reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "TTP reduction"^^xsd:string) AnnotationAssertion(rdfs:label "TTP reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:1.17.4.2-RXN"^^xsd:string) "Catalysis of the reaction: dTTP + thioredoxin disulfide + H2O = TTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CTP reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:1.17.4.2-RXN"^^xsd:string) "Catalysis of the reaction: dCTP + thioredoxin disulfide + H2O = CTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin."^^xsd:string) AnnotationAssertion( "CTP reduction"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.26"^^xsd:string) Annotation( "MetaCyc:COBALAMINSYN-RXN"^^xsd:string) "Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole = GMP + adenosylcobalamin."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.26"^^xsd:string) "cobalamin (5'-phosphate) synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.26"^^xsd:string) "CobS"^^xsd:string) AnnotationAssertion( "cobalamin synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "adenosylcobinamide-GDP ribazoletransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.26"^^xsd:string) "cobalamin-5'-phosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.8.26"^^xsd:string) "adenosylcobinamide-GDP:alpha-ribazole ribazoletransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "S-adenosyl methionine:tRNA ribosyltransferase-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12731872"^^xsd:string) "Catalysis of the reaction: S-adenosylmethionine + 7-(aminomethyl)-7-deazaguanosine-tRNA = adenine + methionine + epoxyqueuosine-tRNA. 7-(aminomethyl)-7-deazaguanosine-tRNA is also known as preQ1-tRNA, and epoxyqueuosine-tRNA as oQ-tRNA."^^xsd:string) AnnotationAssertion(rdfs:label "S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "chaperone activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with an unfolded protein."^^xsd:string) AnnotationAssertion( "binding unfolded ER proteins"^^xsd:string) AnnotationAssertion(rdfs:label "unfolded protein binding"^^xsd:string) AnnotationAssertion( "histone-specific chaperone activity"^^xsd:string) AnnotationAssertion( "ribosomal chaperone activity"^^xsd:string) AnnotationAssertion( "tubulin-specific chaperone activity"^^xsd:string) AnnotationAssertion( "glycoprotein-specific chaperone activity"^^xsd:string) AnnotationAssertion( "fimbrium-specific chaperone activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "co-chaperonin activity"^^xsd:string) AnnotationAssertion(rdfs:label "chaperone binding"^^xsd:string) AnnotationAssertion( "co-chaperone activity"^^xsd:string) AnnotationAssertion( "chaperone protein binding"^^xsd:string) AnnotationAssertion(Annotation( "http://www.onelook.com"^^xsd:string) "Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "carnitine synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:DCARNCOALIG-RXN"^^xsd:string) "Catalysis of the reaction: D-carnitine + CoA + ATP = AMP + diphosphate + D-carnitinyl-CoA."^^xsd:string) AnnotationAssertion( "crotonobetaine/carnitine-CoA ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "carnitine-CoA ligase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "crotonobetaine-CoA synthase activity"^^xsd:string) AnnotationAssertion( "crotonobetaine/carnitine-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:CROTCOALIG-RXN"^^xsd:string) "Catalysis of the reaction: CoA + crotono-betaine + ATP = AMP + diphosphate + crotonobetainyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "crotonobetaine-CoA ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cobaltochelatase activity"^^xsd:string) AnnotationAssertion( "hydrogenobyrinic acid a,c-diamide cobaltochelatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.6.1.2"^^xsd:string) "hydrogenobyrinic-acid-a,c-diamide:cobalt cobalt-ligase (ADP-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.6.1.2"^^xsd:string) Annotation( "RHEA:15344"^^xsd:string) "Catalysis of the reaction: ATP + Co(2+) + H(2)O + hydrogenobyrinate a,c-diamide = ADP + cob(II)yrinate a,c diamide + 4 H(+) + phosphate."^^xsd:string) AnnotationAssertion( "CobNST"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.6.1.2"^^xsd:string) "CobN-CobST"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ATPase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.59"^^xsd:string) "mutanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.59"^^xsd:string) "endo-1,3-alpha-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.59"^^xsd:string) "endo-1,3-alpha-D-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.59"^^xsd:string) "endo-(1->3)-alpha-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.59"^^xsd:string) "1,3(1,3;1,4)-alpha-D-glucan 3-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.59"^^xsd:string) "cariogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucan endo-1,3-alpha-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.59"^^xsd:string) "Catalysis of the endohydrolysis of (1->3)-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.59"^^xsd:string) "cariogenanase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a sugar from one side of the membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides."^^xsd:string) AnnotationAssertion( "sugar/polyol channel activity"^^xsd:string) AnnotationAssertion(rdfs:label "sugar transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hepoxilin A3 synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15123652"^^xsd:string) "Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate. 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid is also known as 12S-HpETE, and (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate as hepoxilin A3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "metal ion:hydrogen antiporter activity"^^xsd:string) AnnotationAssertion( "metal ion:proton antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: metal ion(in) + H+(out) = metal ion(out) + H+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "vitamin or cofactor transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "vitamin transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of vitamins into, out of or within a cell, or between cells. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "vitamin or cofactor transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "cofactor transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of a cofactor into, out of or within a cell, or between cells. A cofactor is a substance that is required for the activity of an enzyme or other protein."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "coenzyme transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of a coenzyme into, out of or within a cell, or between cells. A coenzyme is any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein."^^xsd:string) AnnotationAssertion(rdfs:label "prosthetic group binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "vanadium ion binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with vanadium (V) ions."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "DOI:10.1016/S0040-4020(03)00944-X"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "http://www.onelook.com/"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which both atoms of oxygen from one molecule of O2 are incorporated into the (reduced) product(s) of the reaction. The two atoms of oxygen may be distributed between two different products."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phosphorylated protein binding"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoprotein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a phosphorylated protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "MOG transacylation"^^xsd:string) AnnotationAssertion( "monooleoylglycerol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mono-olein transacylation activity"^^xsd:string) AnnotationAssertion( "acyl-CoA-independent mono-olein transacylation"^^xsd:string) AnnotationAssertion( "mono-oleoylglycerol transacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:15364929"^^xsd:string) "Catalysis of the reaction: mono-olein + mono-olein = diolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol."^^xsd:string) AnnotationAssertion( "monooleoylglycerol transacylase activity"^^xsd:string) AnnotationAssertion( "monoolein transacylation"^^xsd:string) AnnotationAssertion( "mono-oleoylglycerol O-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:15364929"^^xsd:string) "Catalysis of the reaction: diolein + mono-olein = triolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol, and triolein as trioleoylglycerol and olein."^^xsd:string) AnnotationAssertion( "dioleoylglycerol O-acyltransferase activity"^^xsd:string) AnnotationAssertion( "acyl-CoA-independent diolein transacylation"^^xsd:string) AnnotationAssertion(rdfs:label "diolein transacylation activity"^^xsd:string) AnnotationAssertion( "dioleoylglycerol transacylase activity"^^xsd:string) AnnotationAssertion( "DOG transacylation"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.99.1.4"^^xsd:string) "SirB"^^xsd:string) AnnotationAssertion( "sirohydrochlorin ferro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.4"^^xsd:string) "Met8P"^^xsd:string) AnnotationAssertion(rdfs:label "sirohydrochlorin ferrochelatase activity"^^xsd:string) AnnotationAssertion( "siroheme synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.4"^^xsd:string) "CysG"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.4"^^xsd:string) Annotation( "RHEA:24363"^^xsd:string) "Catalysis of the reaction: siroheme + 2 H+ = Fe(2+) + sirohydrochlorin."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.99.1.4"^^xsd:string) "siroheme ferro-lyase (sirohydrochlorin-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:14985347"^^xsd:string) Annotation( "PMID:15452134"^^xsd:string) "Catalysis of the reaction: ethanolamine phosphate + Man-alpha-(1,2)-Man-alpha-(1,2)-Man-alpha-(1,6)-R = Man-alpha-(1,2)-Man-alpha-6-P-EtN-(1,2)-Man-alpha-(1,6)-R; R is Man-alpha(1,4)-GlcNH2-inositol-PO4-lipid. This reaction is the transfer of ethanolamine phosphate to C6 of second mannose in the GPI lipid precursor CP2."^^xsd:string) AnnotationAssertion( "CP2 EtN-P transferase activity"^^xsd:string) AnnotationAssertion( "gpi7 activity"^^xsd:string) AnnotationAssertion( "addition of ethanolamine phosphate to mannose of GPI precursor CP2"^^xsd:string) AnnotationAssertion( "CP2 ethanolamine phosphate transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "CP2 mannose-ethanolamine phosphotransferase activity"^^xsd:string) AnnotationAssertion( "CP2 phosphoethanolamine transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-keto amide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:15564669"^^xsd:string) "Catalysis of the reaction: alpha-keto amide + 2 H+ (from donor) = (R)-hydroxy amide. Alpha-keto amides are of the form R-CO-CONH2, where R may be aromatic or aliphatic."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-keto ester reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:15564669"^^xsd:string) "Catalysis of the reaction: alpha-keto ester + 2 H+ (from donor) = (R)-hydroxy ester. Alpha-keto esters are of the form R(1)-CO-CO-O-R(2), where the R groups may be aromatic or aliphatic."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NAD binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH."^^xsd:string) AnnotationAssertion( "nicotinamide adenine dinucleotide binding"^^xsd:string) AnnotationAssertion( "NAD+ or NADH binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "NAD or NADH binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "alpha-actinin 2 binding"^^xsd:string) AnnotationAssertion(rdfs:label "muscle alpha-actinin binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10984498"^^xsd:string) Annotation( "PMID:11699871"^^xsd:string) Annotation( "PMID:15014165"^^xsd:string) "Interacting selectively and non-covalently with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc."^^xsd:string) AnnotationAssertion( "alpha-actinin 3 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "calsarcin 3 binding"^^xsd:string) AnnotationAssertion( "FATZ 3 binding"^^xsd:string) AnnotationAssertion(rdfs:label "FATZ binding"^^xsd:string) AnnotationAssertion( "FATZ 2 binding"^^xsd:string) AnnotationAssertion( "FATZ 1 binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10984498"^^xsd:string) Annotation( "PMID:11699871"^^xsd:string) "Interacting selectively and non-covalently with a member of the FATZ family of proteins, filamin-, actinin-, and telethonin-binding proteins of the Z-disc of striated muscle. FATZ proteins are located in the Z-disc of the sarcomere and are involved in a complex network of interactions with other Z-band components."^^xsd:string) AnnotationAssertion( "calsarcin 1 binding"^^xsd:string) AnnotationAssertion( "filamin-, actinin- and telethonin-binding protein of the Z-disc of striated muscle"^^xsd:string) AnnotationAssertion( "calsarcin 2 binding"^^xsd:string) AnnotationAssertion( "calsarcin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "phosphoethanolamine transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannose-ethanolamine phosphotransferase activity"^^xsd:string) AnnotationAssertion( "addition of ethanolamine phosphate to mannose of GPI precursor"^^xsd:string) AnnotationAssertion( "EtN-P transferase activity"^^xsd:string) AnnotationAssertion( "ethanolamine phosphate transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15632136"^^xsd:string) "Catalysis of the transfer of ethanolamine phosphate to a mannose residue in the GPI lipid precursor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "serotonin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties."^^xsd:string) AnnotationAssertion( "5-hydroxytryptamine binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "adrenaline binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine."^^xsd:string) AnnotationAssertion(rdfs:label "epinephrine binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine."^^xsd:string) AnnotationAssertion( "noradrenaline binding"^^xsd:string) AnnotationAssertion(rdfs:label "norepinephrine binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histamine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "tRNA cytidine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15037780"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of a tRNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "alpha-actinin 4 binding"^^xsd:string) AnnotationAssertion( "alpha-actinin 1 binding"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-actinin binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10984498"^^xsd:string) Annotation( "PMID:11699871"^^xsd:string) Annotation( "PMID:15014165"^^xsd:string) "Interacting selectively and non-covalently with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats."^^xsd:string) AnnotationAssertion( "nonmuscle alpha-actinin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Bcl-2 homology domain binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11048732"^^xsd:string) Annotation( "PMID:12133724"^^xsd:string) Annotation( "PMID:9020082"^^xsd:string) Annotation( "PMID:9704409"^^xsd:string) "Interacting selectively and non-covalently with the Bcl-2 homology (BH) domain of a protein. Bcl-2-related proteins share homology in one to four conserved regions designated the Bcl-2 homology (BH) domains BH1, BH2, BH3 and BH4. These domains contribute at multiple levels to the function of these proteins in cell death and survival. Anti-apoptotic members of the Bcl-2 family have four BH domains (BH1-BH4). Pro-apoptotic members have fewer BH domains."^^xsd:string) AnnotationAssertion(rdfs:label "BH domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "calponin homology domain binding"^^xsd:string) AnnotationAssertion(rdfs:label "CH domain binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11911887"^^xsd:string) Annotation( "Prosite:PDOC50021"^^xsd:string) "Interacting selectively and non-covalently with the calponin homology domain of a protein, a domain of 100 residues that occurs in signaling and cytoskeletal proteins."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "dihydroxyacetone-phosphate:inorganic phosphate antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerone phosphate(out) + phosphate(in) = glycerone phosphate(in) + phosphate(out)."^^xsd:string) AnnotationAssertion(rdfs:label "glycerone phosphate:inorganic phosphate antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glyceraldehyde 3-phosphate:inorganic phosphate antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glyceraldehyde 3-phosphate(out) + phosphate(in) = glyceraldehyde 3-phosphate(in) + phosphate(out)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "CRH binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "CRF binding"^^xsd:string) AnnotationAssertion( "corticotropin-releasing factor binding"^^xsd:string) AnnotationAssertion(rdfs:label "corticotropin-releasing hormone binding"^^xsd:string) AnnotationAssertion(Annotation( "http://www.onelook.com"^^xsd:string) "Interacting selectively and non-covalently with corticotropin-releasing hormone, a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland."^^xsd:string) AnnotationAssertion( "corticoliberin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "PID binding"^^xsd:string) AnnotationAssertion( "phosphotyrosine-interacting domain binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15924411"^^xsd:string) Annotation( "Pfam:PF02174.5"^^xsd:string) "Interacting selectively and non-covalently with a phosphotyrosine-binding (PTB) domain of a protein."^^xsd:string) AnnotationAssertion(rdfs:label "PTB domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a receptor for hormones."^^xsd:string) AnnotationAssertion(rdfs:label "hormone receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "polypeptide hormone receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "peptide hormone receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a receptor for peptide hormones."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "CRHR binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a receptor for corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "CRF receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "CRH receptor binding"^^xsd:string) AnnotationAssertion( "corticotropin releasing factor receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "corticotropin-releasing hormone receptor binding"^^xsd:string) AnnotationAssertion( "corticotropin releasing factor receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "corticotropin-releasing factor receptor binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "CRHR1 binding"^^xsd:string) AnnotationAssertion( "type 1 corticotropin releasing factor receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "corticotropin-releasing hormone receptor 1 binding"^^xsd:string) AnnotationAssertion( "type 1 corticotropin releasing factor receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15134857"^^xsd:string) "Interacting selectively and non-covalently with the corticotropin-releasing hormone receptor 1 (CRHR1). CRHR1 is the major subtype in the pituitary corticotroph, and mediates the stimulatory actions of corticotropin-releasing hormone on corticotropin hormone secretion. CRHR1 are also located in cortical areas of the brain, cerebellum and limbic system."^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "type 1 corticotropin-releasing factor receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "type 2 corticotropin-releasing factor receptor binding"^^xsd:string) AnnotationAssertion( "type 2 corticotropin releasing factor receptor binding"^^xsd:string) AnnotationAssertion( "CRHR2 binding"^^xsd:string) AnnotationAssertion( "type 2 corticotropin releasing factor receptor ligand"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15134857"^^xsd:string) "Interacting selectively and non-covalently with the corticotropin-releasing hormone receptor type 2 (CRHR2). The CRHR2 has several splice variants that are located in sub-cortical areas of the brain and in the periphery."^^xsd:string) AnnotationAssertion(rdfs:label "corticotropin-releasing hormone receptor 2 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11048732"^^xsd:string) Annotation( "PMID:12133724"^^xsd:string) Annotation( "PMID:9020082"^^xsd:string) Annotation( "PMID:9704409"^^xsd:string) Annotation( "Prosite:PS01080"^^xsd:string) "Interacting selectively and non-covalently with the BH1 domain of a protein of the Bcl-2 family. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists."^^xsd:string) AnnotationAssertion(rdfs:label "BH1 domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11048732"^^xsd:string) Annotation( "PMID:12133724"^^xsd:string) Annotation( "PMID:9020082"^^xsd:string) Annotation( "PMID:9704409"^^xsd:string) Annotation( "Prosite:PS01258"^^xsd:string) "Interacting selectively and non-covalently with the BH2 domain of a protein of the Bcl-2 family. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists."^^xsd:string) AnnotationAssertion(rdfs:label "BH2 domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11048732"^^xsd:string) Annotation( "PMID:12133724"^^xsd:string) Annotation( "PMID:9020082"^^xsd:string) Annotation( "PMID:9704409"^^xsd:string) Annotation( "Prosite:PS01259"^^xsd:string) "Interacting selectively and non-covalently with the BH3 domain of a protein of the Bcl-2 family. The BH3 domain is a potent death domain and has an important role in protein-protein interactions and in cell death."^^xsd:string) AnnotationAssertion(rdfs:label "BH3 domain binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "InterPro:IPR003093"^^xsd:string) Annotation( "PMID:11048732"^^xsd:string) Annotation( "PMID:12133724"^^xsd:string) Annotation( "PMID:9020082"^^xsd:string) Annotation( "PMID:9704409"^^xsd:string) Annotation( "Prosite:PS01260"^^xsd:string) Annotation( "Prosite:PS50063"^^xsd:string) "Interacting selectively and non-covalently with the BH4 domain of a protein of the Bcl-2 family. All anti-apoptotic proteins contain BH1 and BH2 domains; some also contain an additional N-terminal BH4 domain, which is almost never seen in pro-apoptotic proteins. Loss of the BH4 domain can diminish or abrogate anti-apoptotic function or even impart outright death-promoting properties to the protein."^^xsd:string) AnnotationAssertion(rdfs:label "BH4 domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "gonadotrophin releasing hormone binding"^^xsd:string) AnnotationAssertion(rdfs:label "gonadotropin-releasing hormone binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pr"^^xsd:string) Annotation( "PMID:1984190"^^xsd:string) "Interacting selectively and non-covalently with gonadotropin-releasing hormone (GnRH), a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus."^^xsd:string) AnnotationAssertion( "GnRH binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "thyrotropin releasing hormone binding"^^xsd:string) AnnotationAssertion(rdfs:label "thyrotropin-releasing hormone binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with thyrotropin-releasing hormone, a tripeptide hormone that stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary and it is produced by the hypothalamus and travels across the median eminence to the pituitary via the pituitary portal system."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of ectoine from one side of the membrane to the other. Ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid) is a tetrahydropyrimidine commonly synthesized by halophilic bacteria."^^xsd:string) AnnotationAssertion(rdfs:label "ectoine transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucosylglycerol transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) "Catalysis of the transfer of a glucosylglycerol from one side of the membrane to the other. A glucosylglycerol is an alpha-D-glucopyranosyl-alpha-(1,2)-glycerol."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mannosylglycerate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:15034926"^^xsd:string) "Catalysis of the transfer of a mannosylglycerate from one side of the membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-8528"^^xsd:string) "Catalysis of the reaction: geranylgeranyl diphosphate = 9alpha-copalyl diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "syn-copalyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion( "diterpene cyclase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D-aminoacyl-tRNA deacylase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14527667"^^xsd:string) "Catalysis of the reaction: D-aminoacyl-tRNA = D-amino acid + tRNA. Hydrolysis of the removal of D-amino acids from residues in charged tRNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:14527667"^^xsd:string) "Catalysis of the reaction: D-tyrosyl-tRNA(Tyr) = D-tyrosine + tRNA(Tyr). Hydrolysis of the removal of D-tyrosine from tyrosine residues in charged tRNA."^^xsd:string) AnnotationAssertion(rdfs:label "D-tyrosyl-tRNA(Tyr) deacylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: UDP-glucose + a sterol = UDP + O-glucosyl-cholesterol."^^xsd:string) AnnotationAssertion(rdfs:label "cholesterol UDP-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: UDP-glucose + a sterol = UDP + O-glucosyl-ergosterol."^^xsd:string) AnnotationAssertion(rdfs:label "ergosterol UDP-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: UDP-glucose + a sterol = UDP + O-glucosyl-beta-sitosterol."^^xsd:string) AnnotationAssertion(rdfs:label "beta-sitosterol UDP-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: UDP-glucose + a sterol = UDP + O-glucosyl-stigmasterol."^^xsd:string) AnnotationAssertion(rdfs:label "stigmasterol UDP-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: UDP-glucose + a sterol = UDP + O-glucosyl-tomatidine."^^xsd:string) AnnotationAssertion(rdfs:label "tomatidine UDP-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "NFATc2 binding"^^xsd:string) AnnotationAssertion( "NFATx binding"^^xsd:string) AnnotationAssertion( "non-calcium-regulated NFAT protein binding"^^xsd:string) AnnotationAssertion( "NFAT3 protein binding"^^xsd:string) AnnotationAssertion( "nuclear factor of activated T cell protein binding"^^xsd:string) AnnotationAssertion( "NFATc binding"^^xsd:string) AnnotationAssertion( "NFAT2 protein binding"^^xsd:string) AnnotationAssertion( "NFAT binding"^^xsd:string) AnnotationAssertion( "NFATp binding"^^xsd:string) AnnotationAssertion(rdfs:label "NFAT protein binding"^^xsd:string) AnnotationAssertion( "NFATc4 binding"^^xsd:string) AnnotationAssertion( "NFAT1 protein binding"^^xsd:string) AnnotationAssertion( "NFAT5 protein binding"^^xsd:string) AnnotationAssertion( "NFAT4 protein binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15928679"^^xsd:string) "Interacting selectively and non-covalently with NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors. NFAT proteins have crucial roles in the development and function of the immune system."^^xsd:string) AnnotationAssertion( "NFATc3 binding"^^xsd:string) AnnotationAssertion( "NFATc1 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "iron-sulfur cluster binding"^^xsd:string) AnnotationAssertion( "iron sulphur cluster binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with an iron-sulfur cluster, a combination of iron and sulfur atoms."^^xsd:string) AnnotationAssertion( "iron-sulphur cluster binding"^^xsd:string) AnnotationAssertion( "Fe/S binding"^^xsd:string) AnnotationAssertion( "iron sulfur cluster binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "2Fe-2S cluster binding"^^xsd:string) AnnotationAssertion( "diiron disulfide cluster binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:15952888"^^xsd:string) Annotation( "Wikipedia:Iron-sulfur_cluster"^^xsd:string) "Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands."^^xsd:string) AnnotationAssertion( "2 iron, 2 sulphur cluster binding"^^xsd:string) AnnotationAssertion( "iron-sulphur cluster 2Fe-2S binding"^^xsd:string) AnnotationAssertion( "iron-sulfur cluster 2Fe-2S binding"^^xsd:string) AnnotationAssertion( "2 Fe 2 S cluster binding"^^xsd:string) AnnotationAssertion(rdfs:label "2 iron, 2 sulfur cluster binding"^^xsd:string) AnnotationAssertion( "diiron disulphide cluster binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3Fe-4S cluster binding"^^xsd:string) AnnotationAssertion(rdfs:label "3 iron, 4 sulfur cluster binding"^^xsd:string) AnnotationAssertion( "3 Fe 4 S cluster binding"^^xsd:string) AnnotationAssertion( "3 iron, 4 sulphur cluster binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:15952888"^^xsd:string) Annotation( "Wikipedia:Iron-sulfur_cluster"^^xsd:string) "Interacting selectively and non-covalently with a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing."^^xsd:string) AnnotationAssertion( "triiron tetrasulphide cluster binding"^^xsd:string) AnnotationAssertion( "iron-sulfur cluster 3Fe-4S binding"^^xsd:string) AnnotationAssertion( "iron-sulphur cluster 3Fe-4S binding"^^xsd:string) AnnotationAssertion( "triiron tetrasulfide cluster binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4 iron, 4 sulfur cluster binding"^^xsd:string) AnnotationAssertion( "4 iron, 4 sulphur cluster binding"^^xsd:string) AnnotationAssertion( "iron-sulphur cluster 4Fe-4S binding"^^xsd:string) AnnotationAssertion( "tetrairon tetrasulphide cluster binding"^^xsd:string) AnnotationAssertion( "tetrairon tetrasulfide cluster binding"^^xsd:string) AnnotationAssertion( "4 Fe 4 S cluster binding"^^xsd:string) AnnotationAssertion( "4Fe-4S cluster binding"^^xsd:string) AnnotationAssertion( "iron-sulfur cluster 4Fe-4S binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "PMID:15952888"^^xsd:string) Annotation( "Wikipedia:Iron-sulfur_cluster"^^xsd:string) "Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jsg"^^xsd:string) "Interacting selectively and non-covalently with a cluster of atoms including both metal ions and nonmetal atoms, usually sulfur and oxygen. Examples include iron-sulfur clusters and nickel-iron-sulfur clusters."^^xsd:string) AnnotationAssertion(rdfs:label "metal cluster binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "anthocyanidin 3-glucoside-rhamnosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "anthocyanidin-3-glucoside rhamnosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8130800"^^xsd:string) "Catalysis of the reaction: anthocyanidin 3-glucoside + UDP-rhamnose = anthocyanidin 3-rutinoside + UDP."^^xsd:string) AnnotationAssertion( "3RT activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11251121"^^xsd:string) Annotation( "PMID:16120966"^^xsd:string) "Catalysis of the beta-elimination of the 5' deoxyribose-5-phosphate at an abasic site in DNA where a DNA-(apurinic or apyrimidinic site) lyase has already cleaved the C-O-P bond 3' to the apurinic or apyrimidinic site."^^xsd:string) AnnotationAssertion(rdfs:label "5'-deoxyribose-5-phosphate lyase activity"^^xsd:string) AnnotationAssertion( "dRP lyase activity"^^xsd:string) AnnotationAssertion( "dRPase activity"^^xsd:string) AnnotationAssertion( "5'-deoxyribose phosphate activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "polysaccharide beta-fructofuranosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "fructan beta-fructosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.80"^^xsd:string) "fructanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.80"^^xsd:string) "beta-D-fructan fructohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.80"^^xsd:string) "Catalysis of the hydrolysis of terminal, non-reducing 2,1- and 2,6-linked beta-D-fructofuranose residues in fructans."^^xsd:string) AnnotationAssertion( "exo-beta-fructosidase activity"^^xsd:string) AnnotationAssertion( "exo-beta-D-fructosidase activity"^^xsd:string) AnnotationAssertion( "fructan exohydrolase activity"^^xsd:string) AnnotationAssertion( "fructan b-fructosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "inulase activity"^^xsd:string) AnnotationAssertion( "endo-inulinase activity"^^xsd:string) AnnotationAssertion( "2,1-beta-D-fructan fructanohydrolase activity"^^xsd:string) AnnotationAssertion( "indoinulinase activity"^^xsd:string) AnnotationAssertion( "exoinulinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.7"^^xsd:string) "Catalysis of the endohydrolysis of 2,1-beta-D-fructosidic linkages in inulin."^^xsd:string) AnnotationAssertion(rdfs:label "inulinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.57"^^xsd:string) "Catalysis of the hydrolysis of pullulan to isopanose (6-alpha-maltosylglucose)."^^xsd:string) AnnotationAssertion(rdfs:label "isopullulanase activity"^^xsd:string) AnnotationAssertion( "pullulan 4-glucanohydrolase (isopanose-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "saccharopine oxidase activity"^^xsd:string) AnnotationAssertion( "SAX activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16233628"^^xsd:string) "Catalysis of the reaction: L-saccharopine + O2 = L-2-aminoadipic 6-semialdehyde + L-glutamate + H2O2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "proline oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-821"^^xsd:string) "Catalysis of the reaction: L-proline + O2 + H2O = L-delta1-pyrroline-5-carboxylate + H2O2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "FAOD activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16233628"^^xsd:string) "Catalysis of the reaction: fructosyl-amino acid + O2 = corresponding amino acid + glucosone + H2O2."^^xsd:string) AnnotationAssertion(rdfs:label "fructosyl-amino acid oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.-"^^xsd:string) "inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.-"^^xsd:string) "inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.-"^^xsd:string) "inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "MetaCyc:3.1.3.62-RXN"^^xsd:string) "Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) Annotation( "PMID:15689527"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + CpG (in DNA) = S-adenosyl-L-homocysteine + 5-MeCpG (in DNA)."^^xsd:string) AnnotationAssertion(rdfs:label "DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "HpaII methylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "M.BsuRIa"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "HpaII' methylase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) "M.BsuRIb"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) Annotation( "PMID:15689527"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpN = S-adenosyl-L-homocysteine + DNA containing 5-MeCpN."^^xsd:string) AnnotationAssertion(rdfs:label "DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.37"^^xsd:string) Annotation( "PMID:15689527"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpNpG = S-adenosyl-L-homocysteine + DNA containing 5-MeCpNpG."^^xsd:string) AnnotationAssertion(rdfs:label "DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein phosphatase 2A binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with the enzyme protein phosphatase 2A."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein C-terminal methylesterase activity"^^xsd:string) AnnotationAssertion( "protein phosphatase methylesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10318862"^^xsd:string) Annotation( "PMID:8650216"^^xsd:string) "Catalysis of the reaction: C-terminal protein amino acid methyl ester + H2O = protein amino acid + methanol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: protein amino acid methyl ester + H2O = protein amino acid + methanol."^^xsd:string) AnnotationAssertion( "protein carboxylic ester hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein methylesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.-"^^xsd:string) "protein carboxyl methylesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.-"^^xsd:string) "protein methyl-esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.-"^^xsd:string) "PME activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "reduced NAD transporter activity"^^xsd:string) AnnotationAssertion( "NADH transporter activity"^^xsd:string) AnnotationAssertion( "NAD (reduced) transporter activity"^^xsd:string) AnnotationAssertion( "NAD+ transporter activity"^^xsd:string) AnnotationAssertion( "NAD (oxidized) transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of nicotinamide adenine dinucleotide into, out of or within a cell, or between cells; transport may be of either the oxidized form, NAD, or the reduced form, NADH."^^xsd:string) AnnotationAssertion( "oxidized NAD transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "NAD transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "GTP-dependent RNA 5'-hydroxyl-kinase activity"^^xsd:string) AnnotationAssertion( "GTP-dependent polynucleotide 5'-hydroxyl-kinase activity"^^xsd:string) AnnotationAssertion( "GTP-dependent polyribonucleotide kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.78"^^xsd:string) Annotation( "PMID:8428918"^^xsd:string) "Catalysis of the reaction: GTP + 5'-dephospho-RNA = GDP + 5'-phospho-RNA."^^xsd:string) AnnotationAssertion( "GTP-dependent RNA kinase activity"^^xsd:string) AnnotationAssertion( "GTP:5'-dephosphopolyribonucleotide 5'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.78"^^xsd:string) "polynucleotide 5'-hydroxy-kinase activity"^^xsd:string) AnnotationAssertion( "5'-dephosphopolynucleotide kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.78"^^xsd:string) "PNK"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.78"^^xsd:string) "Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.78"^^xsd:string) "polynucleotide kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.78"^^xsd:string) "5'-hydroxyl polynucleotide kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.78"^^xsd:string) "polynucleotide 5'-hydroxyl kinase (phosphorylating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "polynucleotide 5'-hydroxyl-kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.78"^^xsd:string) "Catalysis of the reaction: NTP + 5'-dephospho-RNA = NDP + 5'-phospho-RNA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.78"^^xsd:string) "5'-hydroxyl RNA kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "polyribonucleotide kinase activity"^^xsd:string) AnnotationAssertion( "RNA 5'-hydroxyl kinase activity"^^xsd:string) AnnotationAssertion( "RNA kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.78"^^xsd:string) "5'-hydroxyl polyribonucleotide kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "DNA kinase activity"^^xsd:string) AnnotationAssertion( "DNA 5'-hydroxyl kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "polydeoxyribonucleotide kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.78"^^xsd:string) "Catalysis of the reaction: NTP + 5'-dephospho-DNA = NDP + 5'-phospho-DNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ATP:5'-dephosphopolynucleotide 5'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.78"^^xsd:string) "Catalysis of the reaction: ATP + 5'-dephosphopolynucleotide = ADP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.78"^^xsd:string) "ATP:5'-dephosphopolynucleotide 5'-phosphatase activity"^^xsd:string) AnnotationAssertion( "ATP-dependent polynucleotide 5'-hydroxyl-kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ATP-dependent polynucleotide kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.78"^^xsd:string) "Catalysis of the reaction: GTP + 5'-dephosphopolynucleotide = GDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA."^^xsd:string) AnnotationAssertion( "GTP:5'-dephosphopolynucleotide 5'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "GTP-dependent polynucleotide kinase activity"^^xsd:string) AnnotationAssertion( "GTP-dependent polynucleotide 5'-hydroxyl-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ATP-dependent RNA 5'-hydroxyl-kinase activity"^^xsd:string) AnnotationAssertion( "ATP-dependent RNA kinase activity"^^xsd:string) AnnotationAssertion( "ATP-dependent polynucleotide 5'-hydroxyl-kinase activity"^^xsd:string) AnnotationAssertion( "ATP-dependent polyribonucleotide kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.78"^^xsd:string) "Catalysis of the reaction: ATP + 5'-dephospho-RNA = ADP + 5'-phospho-RNA."^^xsd:string) AnnotationAssertion( "ATP:5'-dephosphopolyribonucleotide 5'-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "GTP-dependent DNA 5'-hydroxyl-kinase activity"^^xsd:string) AnnotationAssertion( "GTP-dependent polydeoxyribonucleotide kinase activity"^^xsd:string) AnnotationAssertion( "GTP-dependent DNA kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.78"^^xsd:string) Annotation( "PMID:8428918"^^xsd:string) "Catalysis of the reaction: GTP + 5'-dephospho-DNA = GDP + 5'-phospho-DNA."^^xsd:string) AnnotationAssertion(rdfs:label "GTP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity"^^xsd:string) AnnotationAssertion( "GTP-dependent polynucleotide 5'-hydroxyl-kinase activity"^^xsd:string) AnnotationAssertion( "GTP:5'-dephosphopolydeoxyribonucleotide 5'-phosphotransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "ISBN:0122146743"^^xsd:string) "Interacting selectively and non-covalently with xanthophylls, any of several neutral yellow to orange carotenoid pigments containing oxygen."^^xsd:string) AnnotationAssertion(rdfs:label "xanthophyll binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ammonia transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:go_curators"^^xsd:string) "Enables the directed movement of ammonia from one side of the membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator."^^xsd:string) AnnotationAssertion( "ethene binding"^^xsd:string) AnnotationAssertion(rdfs:label "ethylene binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "MPBQ methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-methyl-6-phytyl-1,4-benzoquinone methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-2542"^^xsd:string) "Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-phytyl-1,4-benzoquinone + S-adenosyl-homocysteine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-methyl-6-solanyl-1,4-benzoquinone methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-2762"^^xsd:string) "Catalysis of the reaction: 2-methyl-6-solanyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-solanyl-1,4-benzoquinone + S-adenosyl-homocysteine."^^xsd:string) AnnotationAssertion( "MSBQ methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "red chlorophyll catabolite reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10743659"^^xsd:string) "Catalysis of the reaction: red chlorophyll catabolite + reduced ferredoxin + 2 H+ = primary fluorescent catabolite + oxidized ferredoxin. This reaction is the reduction of the C20/C1 double bond in the pyrrole system of red chlorophyll catabolite (RCC) to a colorless tetrapyrrole (pFCC) with a strong blue fluorescence."^^xsd:string) AnnotationAssertion( "RCC reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3,8-divinyl protochlorophyllide a 8-vinyl reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN1F-72"^^xsd:string) "Catalysis of the reaction: divinyl protochlorophyllide a + NADPH + H+ = monovinyl protochlorophyllide a + NADP+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "isopentenyl-diphosphate:NAD(P)+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.2"^^xsd:string) "Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H + H+ = isopentenyl diphosphate + NAD(P)+ + H2O. Note that (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate is an alternative name for 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.2"^^xsd:string) "4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thalianol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15125655"^^xsd:string) "Catalysis of the cyclization of 3(S)-oxidosqualene to (3S,13S,14R)-malabarica-8,17,21-trien-3-ol (thalianol)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cytosine C-5 DNA demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10050851"^^xsd:string) "Catalysis of the reaction: methyl-dCpdG DNA + H2O = dCpdG DNA + methanol. This reaction is the hydrolytic removal of the methyl group on the 5 position of cytosine in DNA."^^xsd:string) AnnotationAssertion(Annotation( "PMID:10050851"^^xsd:string) "DNA demethylase activity"^^xsd:string) AnnotationAssertion( "DNA methyltransferase activity acting on cytosine C-5"^^xsd:string) AnnotationAssertion( "hydrolytic DNA demethylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.64"^^xsd:string) "PsUSP"^^xsd:string) AnnotationAssertion( "UDP-monosaccharide pyrophosphorylase activity"^^xsd:string) AnnotationAssertion( "UDP-monosaccharide diphosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.64"^^xsd:string) Annotation( "PMID:15326166"^^xsd:string) "Catalysis of the reaction: UTP + a monosaccharide 1-phosphate = diphosphate + UDP-monosaccharide."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.64"^^xsd:string) "USP"^^xsd:string) AnnotationAssertion(rdfs:label "UTP-monosaccharide-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.64"^^xsd:string) "UDP-sugar pyrophosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16169896"^^xsd:string) "Catalysis of the reaction: indole acetic acid + S-adenosyl-methionine = methyl indole acetic acid ester + S-adenosyl-homocysteine."^^xsd:string) AnnotationAssertion( "IAA carboxyl methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "indole acetic acid carboxyl methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16040662"^^xsd:string) "Catalysis of the isomerization of 3,5-dienoyl-CoA to 2,4-dienoyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "delta3,5-delta2,4-dienoyl-CoA isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-1,4-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15772281"^^xsd:string) "Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->4) linkage."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.9.5"^^xsd:string) "OK1"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoglucan, water dikinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.5"^^xsd:string) Annotation( "PMID:15618411"^^xsd:string) "Catalysis of the reaction: ATP + [phospho-alpha-glucan] + H2O = AMP + O-phospho-[phospho-alpha-glucan] + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.5"^^xsd:string) "ATP:phospho-alpha-glucan, water phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.9.5"^^xsd:string) "PWD"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "galactomannan beta-1,4-mannosyltransferase activity"^^xsd:string) AnnotationAssertion( "mannan beta-1,4-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14726589"^^xsd:string) "Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-(1->4)-linked mannan backbone in substrates such as galactomannan."^^xsd:string) AnnotationAssertion(rdfs:label "mannan synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: inositol tetrakisphosphate + ATP = inositol pentakisphosphate + ADP."^^xsd:string) AnnotationAssertion(rdfs:label "inositol tetrakisphosphate kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol trisphosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: inositol trisphosphate + ATP = inositol tetrakisphosphate + ADP."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ent-kaurenoic acid oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ent-kaurenoate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.79"^^xsd:string) Annotation( "MetaCyc:RXN1F-159"^^xsd:string) "Catalysis of the reaction: ent-kaurenoate + NADPH + O2 = ent-7-alpha-hydroxykaurenoate + NADP+ + H2O. This is the first of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12)."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.79"^^xsd:string) "ent-kaur-16-en-19-oate,NADPH:oxygen oxidoreductase (hydroxylating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ent-7-alpha-hydroxykaurenoate oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.79"^^xsd:string) Annotation( "MetaCyc:RXN1F-160"^^xsd:string) "Catalysis of the reaction: ent-7-alpha-hydroxykaurenoate + NADPH + H+ + O2 = gibberellin 12-aldehyde + NADP+ + 2 H2O. This is the second of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.79"^^xsd:string) Annotation( "MetaCyc:RXN1F-161"^^xsd:string) "Catalysis of the reaction: gibberellin 12-aldehyde + NADPH + H+ + O2 = gibberellin 12 + NADP+ + H2O. This is the third of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12)."^^xsd:string) AnnotationAssertion( "GA12-aldehyde oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "gibberellin 12-aldehyde oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "all-trans-retinol 13,14-reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.23"^^xsd:string) "retinol saturase activity"^^xsd:string) AnnotationAssertion( "all-trans-13,14-dihydroretinol:acceptor 13,14-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.23"^^xsd:string) Annotation( "RHEA:19196"^^xsd:string) "Catalysis of the reaction: all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH(2). Note that this reaction has only been observed to occur in the opposite direction."^^xsd:string) AnnotationAssertion( "(13,14)-all-trans-retinol saturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.23"^^xsd:string) "RetSat activity"^^xsd:string) AnnotationAssertion( "all-trans-retinol:all-trans-13,14-dihydroretinol saturase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with a misfolded protein."^^xsd:string) AnnotationAssertion(rdfs:label "misfolded protein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "PTEN activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:9811831"^^xsd:string) "Catalysis of the reaction: phosphatidylinositol-3,4-bisphosphate + H2O = phosphatidylinositol-4-phosphate + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "http://www.chem.qmul.ac.uk/iupac/misc/glylp.html#2.1"^^xsd:string) "Interacting selectively and non-covalently with a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "glycolipid binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16362057"^^xsd:string) "Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 36) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 36 of the histone H3 protein."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.27"^^xsd:string) "JHDM1A activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.27"^^xsd:string) "protein-N6,N6-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion( "histone-lysine demethylase activity (H3-K36 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.27"^^xsd:string) "JmjC domain-containing histone demethylase 1A activity"^^xsd:string) AnnotationAssertion( "histone-lysine(H3-K36) demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.27"^^xsd:string) "protein-6-N,6-N-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.27"^^xsd:string) "histone H3-lysine-36 demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.27"^^xsd:string) "histone-lysine (H3-K36) demethylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "histone demethylase activity (H3-K36 specific)"^^xsd:string) AnnotationAssertion( "[histone-H3]-lysine-36 demethylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.27"^^xsd:string) "H3-K36-specific demethylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:nln"^^xsd:string) "Interacting selectively and non-covalently with methotrexate, an antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofolate reductase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA."^^xsd:string) AnnotationAssertion(rdfs:label "methotrexate binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "dihydrofolate binding"^^xsd:string) AnnotationAssertion(rdfs:label "dihydrofolic acid binding"^^xsd:string) AnnotationAssertion( "DHF binding"^^xsd:string) AnnotationAssertion(Annotation( "ISBN:0721662544"^^xsd:string) "Interacting selectively and non-covalently with dihydrofolic acid, a folic acid in which the bicyclic pteridine structure is in the dihydro, partially reduced form; they are intermediates in folate metabolism and are reduced to their tetrahydro, reduced forms."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size."^^xsd:string) AnnotationAssertion( "Hsp90 class protein binding"^^xsd:string) AnnotationAssertion( "Hsp90 binding"^^xsd:string) AnnotationAssertion(rdfs:label "Hsp90 protein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "tetraplex DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16142245"^^xsd:string) Annotation( "PMID:9512530"^^xsd:string) "Interacting selectively and non-covalently with G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "G-quartet DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "G quadruplex DNA binding"^^xsd:string) AnnotationAssertion(rdfs:label "G-quadruplex DNA binding"^^xsd:string) AnnotationAssertion( "G-DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "G quartet binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "G quartet DNA binding"^^xsd:string) AnnotationAssertion( "quadruplex DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "G-quartet binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.284"^^xsd:string) "glutathione-dependent formaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "S-(hydroxymethyl)glutathione dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.284"^^xsd:string) "class III alcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.284"^^xsd:string) "GS-FDH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.284"^^xsd:string) "Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.284"^^xsd:string) "FDH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.284"^^xsd:string) "NAD- and glutathione-dependent formaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.284"^^xsd:string) "ADH3 activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.284"^^xsd:string) "formic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.284"^^xsd:string) "chi-ADH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.284"^^xsd:string) "NAD-dependent formaldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.284"^^xsd:string) "S-(hydroxymethyl)glutathione:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.284"^^xsd:string) "GD-FALDH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.284"^^xsd:string) "NAD-linked formaldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.4.1.22"^^xsd:string) "S-(hydroxymethyl)glutathione formaldehyde-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "S-(hydroxymethyl)glutathione synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.22"^^xsd:string) "S-(hydroxymethyl)glutathione formaldehyde-lyase (glutathione-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.22"^^xsd:string) Annotation( "RHEA:22491"^^xsd:string) "Catalysis of the reaction: S-(hydroxymethyl)glutathione = formaldehyde + glutathione."^^xsd:string) AnnotationAssertion( "glutathione-dependent formaldehyde-activating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.4.1.22"^^xsd:string) "Gfa"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "double-stranded DNA specific 5'-3' exodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a double-stranded DNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "double-stranded DNA 5'-3' exodeoxyribonuclease activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "alkynoate hydratase activity"^^xsd:string) AnnotationAssertion( "acetylenemonocarboxylate hydratase activity"^^xsd:string) AnnotationAssertion(rdfs:label "acetylenecarboxylate hydratase activity, producing 3-hydroxypropenoate"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:ACETYLENECARBOXYLATE-HYDRATASE-RXN"^^xsd:string) "Catalysis of the reaction: 3-hydroxypropenoate = propynoate + H2O."^^xsd:string) AnnotationAssertion( "acetylenecarboxylate hydratase activity"^^xsd:string) AnnotationAssertion( "3-hydroxypropenoate dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.12.98.3"^^xsd:string) "Catalysis of the reaction: H2 + 2-(2,3-dihydropentaprenyloxy)phenazine = 2-dihydropentaprenyloxyphenazine."^^xsd:string) AnnotationAssertion(rdfs:label "Methanosarcina-phenazine hydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.12.98.3"^^xsd:string) "hydrogen:2-(2,3-dihydropentaprenyloxy)phenazine oxidoreductase activity"^^xsd:string) AnnotationAssertion( "coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity"^^xsd:string) AnnotationAssertion( "methylviologen-reducing hydrogenase activity"^^xsd:string) AnnotationAssertion( "methanophenazine hydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CoB--CoM heterodisulfide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.98.1"^^xsd:string) "Catalysis of the reaction: coenzyme B + coenzyme M + methanophenazine = N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine + dihydromethanophenazine."^^xsd:string) AnnotationAssertion( "heterodisulfide reductase activity"^^xsd:string) AnnotationAssertion( "coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity"^^xsd:string) AnnotationAssertion( "coenzyme B--coenzyme M heterodisulfide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.98.1"^^xsd:string) "soluble heterodisulfide reductase activity"^^xsd:string) AnnotationAssertion( "CoB-CoM heterodisulfide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.8.98.1"^^xsd:string) "coenzyme B:coenzyme M:methanophenazine oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Interacting selectively and non-covalently with granulocyte colony-stimulating factor, G-CSF."^^xsd:string) AnnotationAssertion( "granulocyte colony stimulating factor binding"^^xsd:string) AnnotationAssertion( "G-CSF binding"^^xsd:string) AnnotationAssertion(rdfs:label "granulocyte colony-stimulating factor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "PRDX activity"^^xsd:string) AnnotationAssertion(rdfs:label "peroxiredoxin activity"^^xsd:string) AnnotationAssertion( "alkyl hydroperoxide reductase C22 activity"^^xsd:string) AnnotationAssertion( "AhpC activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.15"^^xsd:string) "Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.15"^^xsd:string) "thiol-containing-reductant:hydroperoxide oxidoreductase activity"^^xsd:string) AnnotationAssertion( "Prx activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.5.10"^^xsd:string) "adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase (ADP-forming)"^^xsd:string) AnnotationAssertion( "Ado-cobyric acid synthase [glutamine hydrolyzing] activity"^^xsd:string) AnnotationAssertion( "cobyric acid synthase activity"^^xsd:string) AnnotationAssertion( "5'-deoxy-5'-adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase activity"^^xsd:string) AnnotationAssertion(rdfs:label "adenosylcobyric acid synthase (glutamine-hydrolyzing) activity"^^xsd:string) AnnotationAssertion( "CobQ activity"^^xsd:string) AnnotationAssertion( "adenosylcobyric acid synthase (glutamine-hydrolysing) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.5.10"^^xsd:string) Annotation( "RHEA:23259"^^xsd:string) "Catalysis of the reaction: 4 L-glutamine + adenosylcob(III)yrinate a,c-diamide + 4 ATP + 4 H(2)O = 4 L-glutamate + adenosylcobyrate + 4 ADP + 8 H(+) + 4 phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12730293"^^xsd:string) "Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + cholesterol = adenosine 3',5'-bisphosphate + cholesterol sulfate."^^xsd:string) AnnotationAssertion(rdfs:label "cholesterol sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Interacting selectively and non-covalently with a light intermediate chain of the dynein complex."^^xsd:string) AnnotationAssertion(rdfs:label "dynein light intermediate chain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lysophospholipid transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Enables the directed movement of lysophospholipids into, out of or within a cell, or between cells. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "iron-nicotianamine transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "Fe-NA chelate transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of the iron chelate iron-nicotianamine (Fe-NA) from one side of a membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "copper chelate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "http://www.onelook.com"^^xsd:string) "Catalysis of the transfer of a copper chelate from one side of a membrane to the other. A copper chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "copper-nicotianamine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of the copper chelate copper-nicotianamine (Cu-NA) from one side of a membrane to the other."^^xsd:string) AnnotationAssertion( "Cu-NA chelate transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "coproporphyrinogen dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.22"^^xsd:string) "Catalysis of the reaction: coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.22"^^xsd:string) "coproporphyrinogen III oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.22"^^xsd:string) "coproporphyrinogen-III:S-adenosyl-L-methionine oxidoreductase (decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.22"^^xsd:string) "HemN"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.99.22"^^xsd:string) "radical SAM enzyme activity"^^xsd:string) AnnotationAssertion( "oxygen-independent coproporphyrinogen-III oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.99.2"^^xsd:string) Annotation( "MetaCyc:2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN"^^xsd:string) "Catalysis of the reaction: (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "(R)-2-hydroxyglutarate dehydrogenase activity"^^xsd:string) AnnotationAssertion( "D-2-hydroxyglutarate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:NACGLCTRANS-RXN"^^xsd:string) "Catalysis of the reaction: N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + UDP."^^xsd:string) AnnotationAssertion(rdfs:label "UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.8.13"^^xsd:string) Annotation( "MetaCyc:PHOSNACMURPENTATRANS-RXN"^^xsd:string) "Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine + di-trans,poly-cis-undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol."^^xsd:string) AnnotationAssertion(rdfs:label "UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "abscisic acid glucose ester beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16990135"^^xsd:string) "Catalysis of the reaction: abscisic acid glucose ester + H2O = abscisic acid + beta-D-glucose."^^xsd:string) AnnotationAssertion( "ABA-GE beta-glucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a methyl group to the phosphorus atom of an acceptor molecule."^^xsd:string) AnnotationAssertion(rdfs:label "P-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Se-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a methyl group to the selenium atom of an acceptor molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.21"^^xsd:string) "squalene synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "squalene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.21"^^xsd:string) "Catalysis of the reaction: presqualene diphosphate + NADPH = squalene + NADP+ + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-6201"^^xsd:string) "Catalysis of the reaction: 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H imidazole-5-carboxylate + H+ = S-allantoin + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity"^^xsd:string) AnnotationAssertion( "4-(carbamoylamino)-5-hydroxy-2-oxo-2,5-dihydro-1H-imidazole-5-carboxylate decarboxylase activity"^^xsd:string) AnnotationAssertion( "OHCU decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a methyl group to a carboxyl group on a protein."^^xsd:string) AnnotationAssertion( "protein carboxyl methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein carboxyl O-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.75"^^xsd:string) "Catalysis of the reaction: dimethylallyl diphosphate + tRNA = diphosphate + tRNA containing 6-dimethylallyladenosine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.75"^^xsd:string) "tRNA prenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "tRNA isopentenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.75"^^xsd:string) Annotation( ) "dimethylallyl-diphosphate:tRNA dimethylallyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA dimethylallyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "germacrene-D synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.22"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-germacrene D + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.22"^^xsd:string) "2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(-)-Germacrene D-forming] activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-8574"^^xsd:string) "(E,E)-alpha-farnesene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8574"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,E)-alpha-farnesene + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-farnesene synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.1.81"^^xsd:string) Annotation( "MetaCyc:RXN-5164"^^xsd:string) "Catalysis of the reaction: (+)-isomenthone + NADP+ = (+)-pulegone + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.81"^^xsd:string) "(+)-isomenthone:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(+)-pulegone reductase, (+)-isomenthone as substrate, activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(+)-pulegone reductase, (-)-menthone as substrate, activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.81"^^xsd:string) Annotation( "MetaCyc:RXN-5163"^^xsd:string) "Catalysis of the reaction: (-)-menthone + NADP+ = (+)-pulegone + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.81"^^xsd:string) "(-)-menthone:NADP+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(-)-isopiperitenone reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.82"^^xsd:string) "(+)-cis-isopulegone:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.1.82"^^xsd:string) Annotation( "RHEA:25651"^^xsd:string) "Catalysis of the reaction: (6R)-isoperitenone + H(+) + NADPH = (2R,5R)-isopulegone + NADP(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(+)-menthofuran synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.104"^^xsd:string) "menthofuran synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.104"^^xsd:string) "(+)-pulegone 9-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.104"^^xsd:string) "(+)-MFS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.104"^^xsd:string) "(+)-pulegone,NADPH:oxygen oxidoreductase (9-hydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.104"^^xsd:string) "cytochrome P450 menthofuran synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.104"^^xsd:string) Annotation( "RHEA:25661"^^xsd:string) "Catalysis of the reaction: (R)-pulegone + H(+) + NADPH + O(2) = (R)-menthofuran + 2 H(2)O + NADP(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction in which a halogen in the donor substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on halogen in donors"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of an oxidation-reduction in which a halogen in the donor substance acts as a hydrogen or electron donor and reduces NAD or NADP."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on halogen in donors, with NAD or NADP as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-NH2 group of donors, with a quinone or similar compound as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a quinone or similar compound."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a quinone or similar compound."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on other nitrogenous compounds as donors, with a quinone or similar compound as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.303"^^xsd:string) "(R)-acetoin dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "diacetyl reductase ((R)-acetoin forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.303"^^xsd:string) Annotation( "RHEA:22903"^^xsd:string) "Catalysis of the reaction: (R)-acetoin + NAD(+) = diacetyl + H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.304"^^xsd:string) Annotation( "RHEA:27289"^^xsd:string) "Catalysis of the reaction: (S)-acetoin + NAD(+) = diacetyl + H(+) + NADH."^^xsd:string) AnnotationAssertion(rdfs:label "diacetyl reductase ((S)-acetoin forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.304"^^xsd:string) "(S)-acetoin dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.5.4"^^xsd:string) "(S)-malate:menaquinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.5.4"^^xsd:string) "(S)-malate:(menaquinone) oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "malate dehydrogenase (menaquinone) activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXNI-3"^^xsd:string) "Catalysis of the reaction: (S)-malate + a menaquinone = oxaloacetate + a menaquinol."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN0-5258"^^xsd:string) "Catalysis of the reaction: sn-glycerol 3-phosphate + a ubiquinone = glycerone phosphate + a ubiquinol."^^xsd:string) AnnotationAssertion(rdfs:label "sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:GLYC3PDEHYDROG-RXN"^^xsd:string) "Catalysis of the reaction: sn-glycerol 3-phosphate + ubiquinone-8 = glycerone phosphate + ubiquinol-8."^^xsd:string) AnnotationAssertion(rdfs:label "sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulphur protein as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-1401"^^xsd:string) "Catalysis of the reaction: tryptamine + H2O + O2 = NH3 + indole acetaldehyde + hydrogen peroxide + H+."^^xsd:string) AnnotationAssertion(rdfs:label "tryptamine:oxygen oxidoreductase (deaminating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:AMACETOXID-RXN"^^xsd:string) "Catalysis of the reaction: aminoacetone + H2O + O2 = methylglyoxal + NH3 + hydrogen peroxide + H+."^^xsd:string) AnnotationAssertion(rdfs:label "aminoacetone:oxygen oxidoreductase(deaminating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:AMINEOXID-RXN"^^xsd:string) "Catalysis of the reaction: an aliphatic amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide + H+."^^xsd:string) AnnotationAssertion(rdfs:label "aliphatic-amine oxidase activity"^^xsd:string) AnnotationAssertion( "aliphatic-amine:oxygen oxidoreductase(deaminating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:AMINEPHEN-RXN"^^xsd:string) "Catalysis of the reaction: phenylethylamine + O2 + H2O = phenylacetaldehyde + NH3 + hydrogen peroxide + H+."^^xsd:string) AnnotationAssertion(rdfs:label "phenethylamine:oxygen oxidoreductase (deaminating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "diamine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.22"^^xsd:string) Annotation( ) "diamine:oxygen oxidoreductase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-9599"^^xsd:string) "Catalysis of the reaction: a diamine + H2O + O2 = a monoamine + NH3 + hydrogen peroxide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "KEGG:R02150"^^xsd:string) "1H-Imidazole-4-ethanamine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.22"^^xsd:string) Annotation( ) "histamine:oxygen oxidoreductase (deaminating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "histamine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R02150"^^xsd:string) "1H-Imidazole-4-ethanamine:oxygen oxidoreductase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-9600"^^xsd:string) "Catalysis of the reaction: histamine + H2O + O2 = imidazole-4-acetaldehyde + NH3 + hydrogen peroxide + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methylputrescine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8244"^^xsd:string) "Catalysis of the reaction: N-methylputrescine + H2O + O2 = N-methylaminobutanal + NH3 + hydrogen peroxide + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.22"^^xsd:string) Annotation( ) "N-methylputrescine:oxygen oxidoreductase (deaminating) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "propane-1,3-diamine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-6381"^^xsd:string) "Catalysis of the reaction: propane-1,3-diamine + H2O + O2 = 3-aminopropanal + NH3 + hydrogen peroxide + H+."^^xsd:string) AnnotationAssertion(Annotation( "KEGG:C00986"^^xsd:string) "1,3-diaminopropane oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.3.22"^^xsd:string) Annotation( ) "propane-1,3-diamine:oxygen oxidoreductase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15725"^^xsd:string) "trimethylenediamine oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(S)-limonene 1,2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.107"^^xsd:string) Annotation( ) "(S)-limonene,NAD(P)H:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.107"^^xsd:string) "(-)-limonene 1,2-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-9409"^^xsd:string) "Catalysis of the reaction: (4S)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4S)-limonene-1,2-epoxide."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.107"^^xsd:string) "(-)-limonene,NAD(P)H:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-chloronitrobenzene nitroreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8833"^^xsd:string) "Catalysis of the reaction: 4-chloronitrobenzene + NADPH + H+ = 1-chloro-4-nitrosobenzene + NADP+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1-chloro-4-nitrosobenzene nitroreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8834"^^xsd:string) "Catalysis of the reaction: 1-chloro-4-nitrosobenzene + NADPH + H+ = 1-chloro-4-hydroxylaminobenzene + NADP+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-2561"^^xsd:string) Annotation( "PMID:12213958"^^xsd:string) "Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone = delta-tocopherol."^^xsd:string) AnnotationAssertion(rdfs:label "delta-tocopherol cyclase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "gamma-tocopherol cyclase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-2543"^^xsd:string) Annotation( "PMID:12213958"^^xsd:string) "Catalysis of the reaction: 2,3-dimethyl-6-phytyl-1,4-benzoquinone = gamma-tocopherol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.12.14"^^xsd:string) "chlorophyllide-a oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.14"^^xsd:string) Annotation( "MetaCyc:RXN-7676"^^xsd:string) "Catalysis of the reaction: chlorophyllide a + NADPH + O2 + 2 H+ = 7-hydroxychlorophyllide a + NADP+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "chlorophyllide a oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.14"^^xsd:string) "CAO activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.14"^^xsd:string) "chlorophyllide a:oxygen 7-oxidoreductase activity"^^xsd:string) AnnotationAssertion( "chlorophyll a oxygenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "7-hydroxy-chlorophyllide a oxygenase activity"^^xsd:string) AnnotationAssertion( "chlorophyll b synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.14"^^xsd:string) "chlorophyll-b synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.14"^^xsd:string) "7-hydroxychlorophyllide-a oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.14"^^xsd:string) "CAO activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.14"^^xsd:string) Annotation( "MetaCyc:RXN-7677"^^xsd:string) "Catalysis of the reaction: 7-hydroxychlorophyllide a + NADPH + O2 + H+ = chlorophyllide b + NADP+ + 2 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.12.14"^^xsd:string) "7-hydroxychlorophyllide a:oxygen 7-oxidoreductase activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-8214"^^xsd:string) "Catalysis of the reaction: echinenone + a reduced electron acceptor + oxygen = 3-hydroxyechinenone + an oxidized electron acceptor + H2O."^^xsd:string) AnnotationAssertion( "beta-carotene hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:MONOMER-12386"^^xsd:string) "beta-ring carotenoid 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "echinenone 3-hydroxylase activity"^^xsd:string) AnnotationAssertion( "carotene beta-ring hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-ketotorulene 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8218"^^xsd:string) "Catalysis of the reaction: 4-ketotorulene + a reduced electron acceptor + oxygen = 3-hydroxy-4-ketotorulene + an oxidized electron acceptor + H2O."^^xsd:string) AnnotationAssertion( "beta-carotene hydroxylase activity"^^xsd:string) AnnotationAssertion( "carotene beta-ring hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:MONOMER-12386"^^xsd:string) "beta-ring carotenoid 3-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:MONOMER-12386"^^xsd:string) "beta-ring carotenoid 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-cryptoxanthin hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8026"^^xsd:string) "Catalysis of the reaction: beta-cryptoxanthin + a reduced electron acceptor + oxygen = zeaxanthin + an oxidized electron acceptor + H2O."^^xsd:string) AnnotationAssertion( "beta-carotene hydroxylase activity"^^xsd:string) AnnotationAssertion( "carotene beta-ring hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-carotene 3-hydroxylase activity"^^xsd:string) AnnotationAssertion( "beta-carotene hydroxylase activity"^^xsd:string) AnnotationAssertion( "carotene beta-ring hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:MONOMER-12386"^^xsd:string) "beta-carotene 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8025"^^xsd:string) "Catalysis of the reaction: beta-carotene + a reduced electron acceptor + oxygen = beta-cryptoxanthin + an oxidized electron acceptor + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "adonirubin 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:MONOMER-12386"^^xsd:string) "beta-ring carotenoid 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8187"^^xsd:string) "Catalysis of the reaction: adonirubin + a reduced electron acceptor + oxygen = 3S,3'S-astaxanthin + an oxidized electron acceptor + H2O."^^xsd:string) AnnotationAssertion( "beta-carotene hydroxylase activity"^^xsd:string) AnnotationAssertion( "carotene beta-ring hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "beta-carotene hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "canthaxanthin 3-hydroxylase activity"^^xsd:string) AnnotationAssertion( "carotene beta-ring hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:MONOMER-12386"^^xsd:string) "beta-ring carotenoid 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8186"^^xsd:string) "Catalysis of the reaction: canthaxanthin + a reduced electron acceptor + oxygen = adonirubin + an oxidized electron acceptor + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN0-6444"^^xsd:string) Annotation( "PMID:20369853"^^xsd:string) Annotation( "PMID:20400551"^^xsd:string) "Catalysis of the reaction: uracil + NADH + O2 + H+ = ureidoacrylate peracid + NAD+. Ureidoacrylate peracid is spontaneously reduced by NADH to form ureidoacrylate."^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-6444"^^xsd:string) "pyrimidine oxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "uracil oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:1.14.13.78-RXN"^^xsd:string) "Catalysis of the reaction: H+ + NADPH + ent-kaur-16-ene + oxygen = H2O + NADP+ + ent-kaur-16-en-19-ol."^^xsd:string) AnnotationAssertion(rdfs:label "ent-kaurene oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-5242"^^xsd:string) "Catalysis of the reaction: H+ + NADPH + ent-kaur-16-en-19-ol + oxygen = 2 H2O + NADP+ + ent-kaur-16-en-19-al."^^xsd:string) AnnotationAssertion(rdfs:label "ent-kaur-16-en-19-ol oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ent-kaur-16-en-19-al oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-7580"^^xsd:string) "Catalysis of the reaction: NADPH + ent-kaur-16-en-19-al + oxygen = H2O + NADP+ + ent-kaurenoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-8080"^^xsd:string) "Catalysis of the reaction: GTP + L-glutamate + factor F420-0 = GDP + H+ + factor gamma-F420-1 + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "coenzyme F420-0:L-glutamate ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "coenzyme F420-1:gamma-L-glutamate ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8081"^^xsd:string) "Catalysis of the reaction: GTP + L-glutamate + factor gamma-F420-1 = GDP + H+ + factor gamma-F420-2 + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thymine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8646"^^xsd:string) "Catalysis of the reaction: H2O + thymine + acceptor = 5-methyl-barbiturate + donor-H2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.7.65"^^xsd:string) "GTP:GTP guanylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.65"^^xsd:string) Annotation( "RHEA:24901"^^xsd:string) "Catalysis of the reaction: 2 GTP = cyclic di-3',5'-guanylate + 2 diphosphate + 2 H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "diguanylate cyclase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ATP isopentenyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ATP dimethylallyltransferase activity"^^xsd:string) AnnotationAssertion( "2-isopentenyl-diphosphate:ATP 2-isopentenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R08052"^^xsd:string) "2-isopentenyl-diphosphate:ATP delta2-isopentenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.27"^^xsd:string) "dimethylallyl-diphosphate:ATP dimethylallyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.27"^^xsd:string) Annotation( "MetaCyc:RXN-4303"^^xsd:string) "Catalysis of the reaction: delta(2)-isopentenyl diphosphate + ATP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-triphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.27"^^xsd:string) Annotation( "MetaCyc:RXN-4305"^^xsd:string) "Catalysis of the reaction: delta2-isopentenyl diphosphate + ADP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-diphosphate."^^xsd:string) AnnotationAssertion( "2-isopentenyl-diphosphate:ADP 2-isopentenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R08051"^^xsd:string) "2-isopentenyl-diphosphate:ADP delta2-isopentenyltransferase activity"^^xsd:string) AnnotationAssertion( "ADP isopentenyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.27"^^xsd:string) "dimethylallyl-diphosphate:ADP dimethylallyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ADP dimethylallyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "salicylate methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-phytyl-1,4-naphthoquinone methyltransferase activity"^^xsd:string) AnnotationAssertion( "S-adenosyl-L-methionine:demethylphylloquinone methyltransferase activity"^^xsd:string) AnnotationAssertion( "S-adenosyl-L-methionine:salicylate carboxyl methyltransferase activity"^^xsd:string) AnnotationAssertion( "S-adenosyl-L-methionine:2-phytyl-1,4-naphthoquinone methyltransferase activity"^^xsd:string) AnnotationAssertion( "salicylic acid methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-6723"^^xsd:string) Annotation( "MetaCyc:RXN-7569"^^xsd:string) Annotation( "PMID:14617060"^^xsd:string) "Catalysis of the reaction: demethylphylloquinone + S-adenosyl-L-methionine = phylloquinone + S-adenosyl-L-homocysteine + H+."^^xsd:string) AnnotationAssertion( "SA methyltransferase activity"^^xsd:string) AnnotationAssertion( "demethylphylloquinone methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "p-aminobenzoyl amino acid synthetase activity"^^xsd:string) AnnotationAssertion( "4-aminobenzoyl amino acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10884"^^xsd:string) Annotation( "PMID:19189963"^^xsd:string) "Catalysis of the reaction: 4-aminobenzoate + ATP + amino acid = 4-aminobenzoyl amino acid conjugate + AMP + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "4-aminobenzoate amino acid synthetase activity"^^xsd:string) AnnotationAssertion( "pABA amino acid synthetase activity"^^xsd:string) AnnotationAssertion( "p-aminobenzoate amino acid synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "benzoyl amino acid synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "benzoate amino acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10886"^^xsd:string) Annotation( "PMID:19189963"^^xsd:string) "Catalysis of the reaction: benzoate + ATP + amino acid = benzoyl amino acid conjugate + AMP + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "vanillate amino acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10885"^^xsd:string) Annotation( "PMID:19189963"^^xsd:string) "Catalysis of the reaction: vanillate + ATP + amino acid = vanillate amino acid conjugate + AMP + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "p-hydroxybenzoate amino acid synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10884"^^xsd:string) Annotation( "PMID:19189963"^^xsd:string) "Catalysis of the reaction: 4-hydroxybenzoate + ATP + amino acid = 4-hydroxybenzoyl amino acid conjugate + AMP + diphosphate."^^xsd:string) AnnotationAssertion( "p-hydroxybenzoyl amino acid synthetase activity"^^xsd:string) AnnotationAssertion( "4-hydroxybenzoyl amino acid synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxybenzoate amino acid synthetase activity"^^xsd:string) AnnotationAssertion( "4HBA amino acid synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-10958"^^xsd:string) Annotation( "PMID:19901554"^^xsd:string) "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate + 2 H+."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "N-acetylgalactosamine 1-phosphate uridylyltransferase"^^xsd:string) AnnotationAssertion( "UTP:2-acetamido-2-deoxy-alpha-D-galactose-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion( "N-acetylgalactosamine-1-phosphate uridyltransferase activity"^^xsd:string) AnnotationAssertion( "uridine diphosphoacetylgalactosamine pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.7.23"^^xsd:string) "Catalysis of the reaction: UTP + N-acetyl-alpha-D-galactosamine 1-phosphate = diphosphate + UDP-N-acetyl-D-galactosamine."^^xsd:string) AnnotationAssertion(rdfs:label "UDP-N-acetylgalactosamine diphosphorylase activity"^^xsd:string) AnnotationAssertion( "uridine diphosphate-N-acetylgalactosamine pyrophosphorylase activity"^^xsd:string) AnnotationAssertion( "UDP-N-acetylgalactosamine pyrophosphorylase activity"^^xsd:string) AnnotationAssertion( "uridine diphosphoacetylgalactosamine phosphorylase activity"^^xsd:string) AnnotationAssertion( "UDP-acetylgalactosamine pyrophosphorylase activity"^^xsd:string) AnnotationAssertion( "UTP:N-acetyl-alpha-D-galactosamine-1-phosphate uridylyltransferase activity"^^xsd:string) AnnotationAssertion( "UDP-GalNAc pyrophosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:17600137"^^xsd:string) Annotation( "PMID:9786850"^^xsd:string) "Catalysis of the formation of a double bond between C8 and C9 of the long chain base of a sphingolipid. For example, sphinganine (d18:0) = 8-sphingenine (d18:1delta8); phytosphinganine (t18:0) = 8-phytosphingenine (t18:1delta8); and 4-sphingenine (18:1delta4) = 4,8-sphingadienine (d18:2delta4,8)."^^xsd:string) AnnotationAssertion(rdfs:label "sphingolipid delta-8 desaturase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.1.3"^^xsd:string) "cis-aconitase activity"^^xsd:string) AnnotationAssertion(rdfs:label "isocitrate hydro-lyase (cis-aconitate-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.3"^^xsd:string) "citrate(isocitrate) hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.3"^^xsd:string) "citrate(isocitrate) hydro-lyase (cis-aconitate-forming)"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.3"^^xsd:string) "citrate hydro-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.3"^^xsd:string) Annotation( "GOC:pde"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) Annotation( "MetaCyc:ACONITATEHYDR-RXN"^^xsd:string) "Catalysis of the reaction: cis-aconitate + H2O = isocitrate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.3"^^xsd:string) "aconitate hydratase activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "C-19 gibberellin 2-oxidase activity"^^xsd:string) AnnotationAssertion( "C-19 gibberellin 2beta-hydroxylase activity"^^xsd:string) AnnotationAssertion( "C-19 gibberellin 2-beta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.13"^^xsd:string) Annotation( "GOC:kad"^^xsd:string) "Catalysis of the reaction: a C-19 gibberellin + 2-oxoglutarate + O2 = a C-19 2-beta-hydroxygibberellin + succinate + CO2. C-19 gibberellin refers to a gibberellin with nineteen carbons."^^xsd:string) AnnotationAssertion(rdfs:label "C-19 gibberellin 2-beta-dioxygenase activity"^^xsd:string) AnnotationAssertion( "C-19 gibberellin 2beta-dioxygenase activity"^^xsd:string) AnnotationAssertion( "(C-19 gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating)"^^xsd:string) AnnotationAssertion( "C(19) gibberellin 2-oxidase activity"^^xsd:string) AnnotationAssertion( "C-19 GA 2-oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "C-20 gibberellin 2-beta-dioxygenase activity"^^xsd:string) AnnotationAssertion( "(C-20 gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating)"^^xsd:string) AnnotationAssertion( "C-20 gibberellin 2beta-hydroxylase activity"^^xsd:string) AnnotationAssertion( "C(20) gibberellin 2-oxidase activity"^^xsd:string) AnnotationAssertion( "C-20 GA 2-oxidase activity"^^xsd:string) AnnotationAssertion( "C-20 gibberellin 2-oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.13"^^xsd:string) Annotation( "GOC:kad"^^xsd:string) "Catalysis of the reaction: a C-20 gibberellin + 2-oxoglutarate + O2 = a C-20 2-beta-hydroxygibberellin + succinate + CO2. C-20 gibberellin refers to a gibberellin with twenty carbons."^^xsd:string) AnnotationAssertion( "C-20 gibberellin 2beta-dioxygenase activity"^^xsd:string) AnnotationAssertion( "C-20 gibberellin 2-beta-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor)."^^xsd:string) AnnotationAssertion( "arabinosyl transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arabinosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "MetaCyc:RXN-8319"^^xsd:string) Annotation( "PMID:19682287"^^xsd:string) "Catalysis of the reaction: 1-18:3-3-16:0-phosphatidylglycerol = 1-18:3-3-trans-16:1-phosphatidylglycerol + 2 H+. This reaction is the formation of a trans double bond between carbon 3 and carbon 4 (counting from the carboxyl end) of palmitic acid, which is specifically esterified to the sn-2 glyceryl carbon of phosphatidylglycerol."^^xsd:string) AnnotationAssertion(rdfs:label "delta 3-trans-hexadecenoic acid phosphatidylglycerol desaturase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IBA-glucose synthase activity"^^xsd:string) AnnotationAssertion( "uridine diphosphoglucose-indolebutyrate glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "UDP-glucose:indol-3-ylbutyrate glucosyl-transferase activity"^^xsd:string) AnnotationAssertion( "UDP-glucose:indol-3-ylbutyrate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "indole-3-butyrate beta-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "indole-3-butyric acid glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "UDPG-indol-3-ylbutyryl glucosyl transferase activity"^^xsd:string) AnnotationAssertion( "IBAGlu synthase activity"^^xsd:string) AnnotationAssertion( "UDP-glucose:(indol-3-yl)butyrate beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion( "indol-3-ylbutyrylglucose synthase activity"^^xsd:string) AnnotationAssertion( "UDPglucose:indole-3-butyrate beta-D-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11655"^^xsd:string) "Catalysis of the reaction: indole-3-butyrate + UDP-D-glucose = indole-3-butyryl-beta-1-D-glucose + UDP."^^xsd:string) AnnotationAssertion( "IBA-Glc synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-11659"^^xsd:string) "UDP:glucose:salicylic acid glucosyltransferase (ester-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "salicylic acid glucosyltransferase (ester-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11659"^^xsd:string) "UDP:glucose:SA glucosyltransferase (ester-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11659"^^xsd:string) "UDP:glucose:salicylate glucosyltransferase (ester-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11659"^^xsd:string) "Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid glucose ester + UDP."^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11659"^^xsd:string) "salicylic acid glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11659"^^xsd:string) "UDP:glucose:2-hydroxybenzoic acid glucosyltransferase (ester-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-11658"^^xsd:string) "UDP:glucose:2-hydroxybenzoic acid glucosyltransferase (glucoside-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11658"^^xsd:string) "salicylic acid glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11658"^^xsd:string) "UDP:glucose:SA glucosyltransferase (glucoside-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11658"^^xsd:string) "UDP:glucose:salicylate glucosyltransferase (glucoside-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "salicylic acid glucosyltransferase (glucoside-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11658"^^xsd:string) "Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid 2-O-glucoside + UDP."^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11658"^^xsd:string) "UDP:glucose:salicylic acid glucosyltransferase (glucoside-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-11660"^^xsd:string) "UDP:glucose:benzoate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11660"^^xsd:string) "UDP:glucose:benzoic acid glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11660"^^xsd:string) "Catalysis of the reaction: benzoic acid + UDP-glucose = benzoic acid glucose ester + UDP."^^xsd:string) AnnotationAssertion(rdfs:label "benzoic acid glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11660"^^xsd:string) "benzoate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11660"^^xsd:string) "UDP:glucose:BA glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:20045079"^^xsd:string) Annotation( "PMID:7966317"^^xsd:string) "Catalysis of the reaction: lysophosphatidic acid + H2O = phosphate + monoacylglycerol."^^xsd:string) AnnotationAssertion( "lysophosphatidate phosphatase activity"^^xsd:string) AnnotationAssertion( "LPA phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "lysophosphatidic acid phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.300"^^xsd:string) "all-trans-retinol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.300"^^xsd:string) "NADP(H)-dependent retinol dehydrogenase/reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.300"^^xsd:string) "retinol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.300"^^xsd:string) "retinol dehydrogenase [NADP+] activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:25036"^^xsd:string) "Catalysis of the reaction: all-trans-retinol + NADP+ = all-trans-retinal + NADPH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "NADP-retinol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.300"^^xsd:string) "all-trans retinal reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-leucine transaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.42"^^xsd:string) Annotation( "MetaCyc:BRANCHED-CHAINAMINOTRANSFERLEU-RXN"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamatic acid."^^xsd:string) AnnotationAssertion( "L-leucine aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-valine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.42"^^xsd:string) Annotation( "MetaCyc:BRANCHED-CHAINAMINOTRANSFERVAL-RXN"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoic acid + L-glutamatic acid."^^xsd:string) AnnotationAssertion(rdfs:label "L-valine transaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-isoleucine transaminase activity"^^xsd:string) AnnotationAssertion( "L-isoleucine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.6.1.42"^^xsd:string) Annotation( "MetaCyc:BRANCHED-CHAINAMINOTRANSFERILEU-RXN"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoic acid + L-glutamic acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "purine-6-thiol phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "hypoxanthine-guanine phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "guanylate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "6-hydroxypurine phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "guanine phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "GMP pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "guanosine phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Catalysis of the reaction: GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "Transphosphoribosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "6-mercaptopurine phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "guanosine 5'-phosphate pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "guanylic pyrophosphorylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "guanine-hypoxanthine phosphoribosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.2.8"^^xsd:string) "GPRT"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "L-myo-inositol 1,4,5-trisphosphate-monoesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "D-myo-inositol 1,4,5-trisphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "InsP3 5-phosphatase activity"^^xsd:string) AnnotationAssertion( "inositol triphosphate 5-phosphomonoesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "myo-inositol-1,4,5-trisphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion( "type II inositol polyphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "inosine triphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "inositol polyphosphate-5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "type I inositol-polyphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "InsP(3) 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "inositol phosphate 5-phosphomonoesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "inositol trisphosphate phosphomonoesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "D-myo-inositol(1,4,5)-trisphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "5PTase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "Ins(1,4,5)P3 5-phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol-1,4,5-trisphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "D-myo-inositol 1,4,5-triphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) Annotation( "RHEA:19800"^^xsd:string) "Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "inositol 1,4,5-trisphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) Annotation( "RHEA:11395"^^xsd:string) "Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "D-myo-inositol (1,3,4,5)-polyphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion( "type II inositol polyphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "type I inositol-polyphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "inositol polyphosphate-5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "Ins(1,3,4,5)P4 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "5PTase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.56"^^xsd:string) "Ins(1,3,4,5)P(4) 5-phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "RHEA:23875"^^xsd:string) "Catalysis of the reaction: (R)-propane-1,2-diol + NAD+ = (R)-lactaldehyde + NADH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.77"^^xsd:string) "D-lactaldehyde:propanediol oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.77"^^xsd:string) "(R)-propane-1,2-diol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "R-lactaldehyde reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.77"^^xsd:string) "L-lactaldehyde:propanediol oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.77"^^xsd:string) "(S)-propane-1,2-diol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "S-lactaldehyde reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:15936"^^xsd:string) "Catalysis of the reaction: (S)-propane-1,2-diol + NAD+ = (S)-lactaldehyde + NADH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.90"^^xsd:string) "Catalysis of the reaction: zeaxanthin + NAD(P)H + H+ + O2 = antheraxanthin + NAD(P)+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.90"^^xsd:string) "zea-epoxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "zeaxanthin epoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.90"^^xsd:string) "zeaxanthin,NAD(P)H:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.90"^^xsd:string) "antheraxanthin,NAD(P)H:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "antheraxanthin epoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-7979"^^xsd:string) "Catalysis of the reaction: antheraxanthin + NAD(P)H + H+ + O2 = all-trans-violaxanthin + NAD(P)+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.7.3.1"^^xsd:string) "nitroalkane reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.3.1"^^xsd:string) "NAO activity"^^xsd:string) AnnotationAssertion(rdfs:label "nitroalkane oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.3.1"^^xsd:string) "Catalysis of the reaction: nitroalkane + H2O + O2 = an aldehyde or ketone + nitrite + H2O2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.7.3.1"^^xsd:string) "nitroalkane:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "tRNA uracil 2'-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "S-adenosyl-L-methionine:tRNA (uracil-2'-O-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA (uracil-2'-O-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "S-adenosyl-L-methionine:tRNA uracil-2'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methyluracil."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "tRNA (uracil 2')-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "tRNA uracil-2'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "transfer ribonucleate uracil 2'-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "tRNA cytosine-2'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylcytosine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "S-adenosyl-L-methionine:tRNA cytosine-2'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "S-adenosyl-L-methionine:tRNA (cytosine-2'-O-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "tRNA cytosine 2'-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA (cytosine-2'-O-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "tRNA (cytosine 2')-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.34"^^xsd:string) "transfer ribonucleate cytosine 2'-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "KEGG:R06868"^^xsd:string) Annotation( "MetaCyc:RXN-5642"^^xsd:string) Annotation( "RHEA:25322"^^xsd:string) "Catalysis of the reaction: N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "phosphomethylethanolamine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R06868"^^xsd:string) Annotation( ) "S-adenosyl-L-methionine:methylethanolamine phosphate N-methyltransferase activity"^^xsd:string) AnnotationAssertion( "N-methylethanolamine phosphate N-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kd"^^xsd:string) Annotation( "MetaCyc:RXN-11625"^^xsd:string) "Catalysis of the reaction: farnesol + nucleoside triphosphate = farnesyl monophosphate + nucleoside diphosphate."^^xsd:string) AnnotationAssertion( "farnesol phosphotransferase activity"^^xsd:string) AnnotationAssertion( "trans,trans-farnesol kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "farnesol kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CTP:2-trans,-6-trans-farnesol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11625"^^xsd:string) "Catalysis of the reaction: 2-trans,-6-trans-farnesol + CTP = 2-trans,-6-trans-farnesyl monophosphate + CDP + H+."^^xsd:string) AnnotationAssertion( "CTP:2-trans,-6-trans-farnesol phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "geraniol phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kd"^^xsd:string) "Catalysis of the reaction: geraniol + nucleoside triphosphate = geranyl monophosphate + nucleoside diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "geraniol kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kd"^^xsd:string) Annotation( "MetaCyc:RXN-11629"^^xsd:string) "Catalysis of the reaction: geranylgeraniol + nucleoside triphosphate = all-trans-geranyl-geranyl monophosphate + nucleoside diphosphate."^^xsd:string) AnnotationAssertion( "geranylgeraniol phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "geranylgeraniol kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "CTP:geranylgeraniol phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "CTP:geranylgeraniol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11629"^^xsd:string) "Catalysis of the reaction: geranylgeraniol + CTP = all-trans-geranyl-geranyl monophosphate + CDP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) Annotation( "GOC:kd"^^xsd:string) "Catalysis of the reaction: prenol + nucleoside triphosphate = prenyl phosphate + nucleoside diphosphate activity."^^xsd:string) AnnotationAssertion( "prenyl alcohol phosphotransferase activity"^^xsd:string) AnnotationAssertion( "prenyl alcohol kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "prenol kinase activity"^^xsd:string) AnnotationAssertion( "prenol phosphotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "RHEA:25547"^^xsd:string) "Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-9(11),15-diene + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.31"^^xsd:string) Annotation( ) "ent-copalyl-diphosphate diphosphate-lyase [ent-pimara-9(11),15-diene-forming] activity"^^xsd:string) AnnotationAssertion(rdfs:label "ent-pimara-9(11),15-diene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.31"^^xsd:string) "PMD synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "3-methylbutyraldehyde reductase (NADP) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.265"^^xsd:string) Annotation( "KEGG:R05686"^^xsd:string) "Catalysis of the reaction: 3-methylbutanol + NADP+ = 3-methylbutanal + NADPH + H+. 3-methylbutanal is also known as isovaleraldehyde."^^xsd:string) AnnotationAssertion( "3-methylbutanal reductase (NADP) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.265"^^xsd:string) "3-methylbutanol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-methylbutanol:NADP oxidoreductase activity"^^xsd:string) AnnotationAssertion( "isoamyl alcohol oxidase (NADP) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.265"^^xsd:string) "3-methylbutanol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion( "3-methylbutyraldehyde reductase (NAD) activity"^^xsd:string) AnnotationAssertion(rdfs:label "3-methylbutanol:NAD oxidoreductase activity"^^xsd:string) AnnotationAssertion( "3-methylbutanal reductase (NAD) activity"^^xsd:string) AnnotationAssertion( "isoamyl alcohol oxidase (NAD) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.265"^^xsd:string) Annotation( "KEGG:R05685"^^xsd:string) "Catalysis of the reaction: 3-methylbutanol + NAD+ = 3-methylbutanal + NADH + H+. 3-methylbutanal is also known as isovaleraldehyde."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.287"^^xsd:string) "D-arabinitol:NADP+ dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.287"^^xsd:string) "ARD1p"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.287"^^xsd:string) "NADP+-dependent D-arabinitol dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.287"^^xsd:string) "Catalysis of the reaction: D-arabinitol + NADP+ = D-xylulose + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.287"^^xsd:string) "D-arabinitol dehydrogenase 1 activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "levopimaradiene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:25551"^^xsd:string) "Catalysis of the reaction: (+)-copalyl diphosphate = abieta-8(14),12-diene + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.32"^^xsd:string) Annotation( ) "ent-copalyl-diphosphate diphosphate-lyase [ent-abieta-8(14),12-diene-forming] activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "RHEA:25620"^^xsd:string) "Catalysis of the reaction: terpentedienyl diphosphate = diphosphate + terpentetriene."^^xsd:string) AnnotationAssertion(rdfs:label "terpentetriene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.36"^^xsd:string) Annotation( ) "terpentedienyl-diphosphate diphosphate-lyase (terpentetriene-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.37"^^xsd:string) Annotation( "KEGG:R07830"^^xsd:string) Annotation( ) "(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-epi-isozizaene-forming] activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:25995"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-epi-isozizaene + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "epi-isozizaene synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "KEGG:R08370"^^xsd:string) "bisabolene synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-bisabolene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:25439"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,R)-alpha-bisabolene + diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.38"^^xsd:string) Annotation( ) "(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(E)-alpha-bisabolene-forming] activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "epicedrol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:26118"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = epi-cedrol + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "epi-cedrol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.3.39"^^xsd:string) Annotation( ) "(2E,6E)-farnesyl-diphosphate diphosphate-lyase (8-epi-cedrol-forming) activity"^^xsd:string) AnnotationAssertion( "8-epicedrol synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.3.40"^^xsd:string) Annotation( ) "(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(Z)-gamma-bisabolene-forming] activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:26084"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "(Z)-gamma-bisabolene synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "tryptophan synthase beta subunit activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "L-serine hydro-lyase (adding indole; L-tryptophan-forming) activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-2382"^^xsd:string) "Catalysis of the reaction: indole + L-serine = L-tryptophan + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "KEGG:R06368"^^xsd:string) "Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + ADP + phosphate + perillyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "perillic acid:CoA ligase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0731"^^xsd:string) "perillyl-CoA synthetase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0731"^^xsd:string) "perillyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R06368"^^xsd:string) "Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + AMP + diphosphate + perillyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "perillic acid:CoA ligase (AMP-forming) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0737"^^xsd:string) "3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R06396"^^xsd:string) "Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP + phosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0737"^^xsd:string) "3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R06515"^^xsd:string) "Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + AMP + diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.1"^^xsd:string) "carboxylic esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.1"^^xsd:string) "procaine esterase activity"^^xsd:string) AnnotationAssertion( "serine esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.1"^^xsd:string) "nonspecific carboxylesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.1"^^xsd:string) "triacetin esterase"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.1"^^xsd:string) "cocaine esterase activity"^^xsd:string) AnnotationAssertion( "carboxylic ester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.1"^^xsd:string) "ali-esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.1"^^xsd:string) "esterase A"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1"^^xsd:string) Annotation( "EC:3.1.1.1"^^xsd:string) Annotation( "GOC:curators"^^xsd:string) "Catalysis of the hydrolysis of a carboxylic ester bond."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.1"^^xsd:string) "carboxylate esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.1"^^xsd:string) "carboxyl ester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.1"^^xsd:string) "carboxyesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.1"^^xsd:string) "alpha-carboxylesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.1"^^xsd:string) "Ali-esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.1"^^xsd:string) "B-esterase activity"^^xsd:string) AnnotationAssertion( "carboxylesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.1"^^xsd:string) "vitamin A esterase"^^xsd:string) AnnotationAssertion(rdfs:label "carboxylic ester hydrolase activity"^^xsd:string) AnnotationAssertion( "carboxylic acid esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.1"^^xsd:string) "esterase B"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0028"^^xsd:string) "xenobiotic reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0028"^^xsd:string) "pentaerythritol tetranitrate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_enzymeID:e0251"^^xsd:string) "tetrachlorohydroquinone reductive dehalogenase activity"^^xsd:string) AnnotationAssertion( "trichlorohydroquinone reductive dehalogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r0031"^^xsd:string) Annotation( "UM-BBD_reactionID:r0315"^^xsd:string) "Catalysis of the reaction: 2,3,6-trichlorohydroquinone + 2 glutathione = 2,6-dichlorohydroquinone + glutathione disulfide + HCl."^^xsd:string) AnnotationAssertion(rdfs:label "trichloro-p-hydroquinone reductive dehalogenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.99.30"^^xsd:string) Annotation( "RHEA:28353"^^xsd:string) "Catalysis of the reaction: UDP-beta-L-arabinofuranose = UDP-beta-L-arabinopyranose."^^xsd:string) AnnotationAssertion(rdfs:label "UDP-arabinopyranose mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.30"^^xsd:string) "UDP-L-arabinose mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.30"^^xsd:string) Annotation( ) "UDP-arabinopyranose pyranomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.30"^^xsd:string) "UDP-L-Ara mutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.30"^^xsd:string) "UDP-L-arabinopyranose furanomutase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.99.30"^^xsd:string) "uridine-diphosphate-L-arabinose mutase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "raffinose alpha-galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:20739305"^^xsd:string) "raffinose-specific alkaline alpha-galactosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11502"^^xsd:string) "Catalysis of the reaction: raffinose + H2O = alpha-D-galactose + sucrose."^^xsd:string) AnnotationAssertion( "raffinose galactohydrolase activity"^^xsd:string) AnnotationAssertion( "alkaline alpha-galactosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:21502530"^^xsd:string) "Catalysis of the reaction: epoxyqueuosine in tRNA + reductant = queuosine in tRNA + oxidised reductant."^^xsd:string) AnnotationAssertion(rdfs:label "epoxyqueuosine reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "jasmonoyl-isoleucine-12-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-12421"^^xsd:string) Annotation( "PMID:21576464"^^xsd:string) "Catalysis of the reaction: jasmonoyl-isoleucine + NADPH + H+ + O2 = 12-hydroxy-jasmonoyl-isoleucine + NADP+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.44"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha-methyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha-dimethyl-L-histidine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.44"^^xsd:string) "methylhistidine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.44"^^xsd:string) "histidine-alpha-N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.44"^^xsd:string) "S-adenosyl-L-methionine:alpha-N-dimethyl-L-histidine alpha-N-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methylhistidine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.44"^^xsd:string) "S-adenosyl-L-methionine:N-alpha-dimethyl-L-histidine N-alpha-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.44"^^xsd:string) "S-adenosyl-L-methionine:L-histidine Nalpha-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.44"^^xsd:string) "histidine-alpha-N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.44"^^xsd:string) "histidine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.44"^^xsd:string) "S-adenosyl-L-methionine:L-histidine alpha-N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.44"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + L-histidine = S-adenosyl-L-homocysteine + N-alpha-trimethyl-L-histidine."^^xsd:string) AnnotationAssertion(rdfs:label "histidine N-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol phosphosphingolipid phospholipase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: inositol phosphosphingolipid + H2O = sphingolipid + phosphorylinositol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: inositol phosphorylceramide + H2O = C26-phytoceramide + phosphorylinositol."^^xsd:string) AnnotationAssertion(rdfs:label "inositol phosphorylceramide phospholipase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: mannosyl-inositol phosphorylceramide + H2O = C26-phytoceramide + mannosylphosphorylinositol."^^xsd:string) AnnotationAssertion(rdfs:label "mannosyl-inositol phosphorylceramide phospholipase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: mannosyl-diinositol phosphorylceramide + H2O = C26-phytoceramide + mannosyldiphosphorylinositol."^^xsd:string) AnnotationAssertion(rdfs:label "mannosyl-diinositol phosphorylceramide phospholipase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroquinone:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion( "benzenediol:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.10.3.2"^^xsd:string) "Catalysis of the reaction: 4 hydroquinone + O2 = 4 benzosemiquinone + 4 H2O."^^xsd:string) AnnotationAssertion( "laccase reaction"^^xsd:string) AnnotationAssertion( "p-diphenol:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tRNA-specific adenosine-34 deaminase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17875641"^^xsd:string) "Catalysis of the reaction: adenosine-34 + H2O = inosine-34 + NH3, in a tRNA-Ala molecule."^^xsd:string) AnnotationAssertion( "tRNA(Ala)-A34 deaminase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19401441"^^xsd:string) "Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a ribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-ribose phosphate and 3'-hydroxyl ends."^^xsd:string) AnnotationAssertion(rdfs:label "apurinic/apyrimidinic endoribonuclease activity"^^xsd:string) AnnotationAssertion( "apyrimidinic endoribonuclease activity"^^xsd:string) AnnotationAssertion( "AP endoribonuclease activity"^^xsd:string) AnnotationAssertion( "apurinic endoribonuclease activity"^^xsd:string) AnnotationAssertion( "abasic endoribonuclease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "AP deoxyendoribonuclease activity"^^xsd:string) AnnotationAssertion(rdfs:label "apurinic/apyrimidinic endodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion( "apyrimidinic deoxyendoribonuclease activity"^^xsd:string) AnnotationAssertion( "abasic deoxyendoribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19401441"^^xsd:string) "Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends."^^xsd:string) AnnotationAssertion( "apurinic deoxyendoribonuclease activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fatty acid in-chain hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-12186"^^xsd:string) "Catalysis of the reaction: fatty acid + O2 + 2 NADPH + H+ = fatty acid with in-chain hydroxy group + 2 NADP+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jp"^^xsd:string) Annotation( "PMID:18981179"^^xsd:string) "Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inositol (2,3,4,5,6)pentakisphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "inositol hexakisphosphate 1-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jp"^^xsd:string) Annotation( "PMID:18981179"^^xsd:string) "Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "inositol hexakisphosphate 3-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.127"^^xsd:string) "ATP:1D-myo-inositol-1,3,4-trisphosphate 6-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.127"^^xsd:string) "IP3 6-kinase activity"^^xsd:string) AnnotationAssertion( "1D-myo-inositol-trisphosphate 6-kinase activity"^^xsd:string) AnnotationAssertion( "inositol 1,3,4-trisphosphate 6-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.127"^^xsd:string) "ins(1,3,4)P(3) 6-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.134"^^xsd:string) "Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.127"^^xsd:string) "Ins(1,3,4)P3 6-kinase activity"^^xsd:string) AnnotationAssertion( "inositol-trisphosphate 6-kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol-1,3,4-trisphosphate 6-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "inositol-trisphosphate 5-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.134"^^xsd:string) "Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion( "1D-myo-inositol-trisphosphate 5-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.127"^^xsd:string) "IP3 5-kinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol-1,3,4-trisphosphate 5-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.127"^^xsd:string) "ins(1,3,4)P(3) 5-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.127"^^xsd:string) "ATP:1D-myo-inositol-1,3,4-trisphosphate 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion( "inositol 1,3,4-trisphosphate 5-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.127"^^xsd:string) "Ins(1,3,4)P3 5-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.99.8"^^xsd:string) "capsanthin-capsorubin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.8"^^xsd:string) "CCS"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.8"^^xsd:string) "Catalysis of the reaction: antheraxanthin = capsanthin."^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.8"^^xsd:string) "ketoxanthophyll synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "capsanthin synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.3.99.8"^^xsd:string) "violaxanthin-capsorubin isomerase (ketone-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.8"^^xsd:string) "capsanthin-capsorubin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.8"^^xsd:string) "CCS"^^xsd:string) AnnotationAssertion(rdfs:label "capsorubin synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.8"^^xsd:string) "ketoxanthophyll synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.3.99.8"^^xsd:string) "Catalysis of the reaction: violaxanthin = capsorubin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.157"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine."^^xsd:string) AnnotationAssertion(rdfs:label "dimethylglycine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.157"^^xsd:string) "ApDMT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.157"^^xsd:string) "S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.157"^^xsd:string) "SDMT"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.157"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine."^^xsd:string) AnnotationAssertion(rdfs:label "sarcosine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.157"^^xsd:string) "S-adenosyl-L-methionine:N,N-sarcosine N-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.75"^^xsd:string) "phosphoethanolamine phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphocholine phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.75"^^xsd:string) "Catalysis of the reaction: choline phosphate + H2O = choline + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.75"^^xsd:string) "3X11A"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.75"^^xsd:string) "PHOSPHO1"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.75"^^xsd:string) "phosphoethanolamine phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.75"^^xsd:string) "3X11A"^^xsd:string) AnnotationAssertion(rdfs:label "phosphoethanolamine phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.75"^^xsd:string) "PHOSPHO1"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.75"^^xsd:string) "Catalysis of the reaction: O-phosphoethanolamine + H2O = ethanolamine + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.24"^^xsd:string) "quinic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.24"^^xsd:string) "quinate:NADP(+) 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:18428"^^xsd:string) "Catalysis of the reaction: quinate + NADP+ = 3-dehydroquinate + NADPH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "quinate 3-dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.24"^^xsd:string) "quinate:NADP 3-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.25"^^xsd:string) "shikimate oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.25"^^xsd:string) "DHS reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.25"^^xsd:string) "3-dehydroshikimic reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "shikimate 3-dehydrogenase (NAD+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.25"^^xsd:string) "shikimate:NAD(P)(+) 3-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.25"^^xsd:string) "dehydroshikimic reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.25"^^xsd:string) "shikimate:NAD(P)(+) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.25"^^xsd:string) "3-dehydroshikimate reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:17744"^^xsd:string) "Catalysis of the reaction: shikimate + NAD+ = 3-dehydroshikimate + NADH + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "transfer ribonucleate cytosine 3-methyltransferase activity"^^xsd:string) AnnotationAssertion( "tRNA (cytosine 3)-methyltransferase activity"^^xsd:string) AnnotationAssertion( "tRNA cytosine-3-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tRNA (cytosine-3-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:21518804"^^xsd:string) Annotation( "PMID:21518805"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 3-methylcytosine."^^xsd:string) AnnotationAssertion( "S-adenosyl-L-methionine:tRNA (cytosine-3-)-methyltransferase activity"^^xsd:string) AnnotationAssertion( "tRNA cytosine 3-methyltransferase activity"^^xsd:string) AnnotationAssertion( "S-adenosyl-L-methionine:tRNA cytosine-3-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-glucanase activity"^^xsd:string) AnnotationAssertion( "beta-D-glucanase activity"^^xsd:string) AnnotationAssertion(Annotation( "Wikipedia:Beta-glucan"^^xsd:string) "Catalysis of the hydrolysis of linkages in beta-D-glucans; beta-glucans are polysaccharides of D-glucose monomers linked by beta-glycosidic bonds."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.2.5.1"^^xsd:string) "pyruvate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.5.1"^^xsd:string) "pyruvic dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.5.1"^^xsd:string) "Catalysis of the reaction: a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.5.1"^^xsd:string) "pyruvate:ubiquinone-8-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.5.1"^^xsd:string) Annotation( ) "pyruvate:ubiquinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pyruvate dehydrogenase (quinone) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.5"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a quinone or similar compound."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.32"^^xsd:string) "phosphatidylserine-specific phospholipase A1 activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R04034"^^xsd:string) "Catalysis of the reaction: phosphatidylserine + H2O = 2-acyl-sn-glycero-3-phosphoserine + fatty acid."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylserine 1-acylhydrolase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "BRENDA:3.1.1.32"^^xsd:string) "Catalysis of the reaction: 1-acyl-2-lysophosphatidylserine + H2O = sn-glycerol-phosphoserine + a carboxylate."^^xsd:string) AnnotationAssertion(rdfs:label "1-acyl-2-lysophosphatidylserine acylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.32"^^xsd:string) "phosphatidylserine-specific phospholipase A1 activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.13.80"^^xsd:string) Annotation( "RHEA:18960"^^xsd:string) "Catalysis of the reaction: (4R)-limonene + H+ + NADPH + O2 = (1R,5S)-carveol + H2O + NADP+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.80"^^xsd:string) Annotation( ) "(R)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "(R)-limonene 6-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.80"^^xsd:string) "(+)-limonene 6-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.80"^^xsd:string) "(+)-limonene-6-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidylinositol kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: myo-inositol tetrakisphosphate + H2O = myo-inositol trisphosphate + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "inositol tetrakisphosphate phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidylinositol monophosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: phosphatidylinositol monophosphate + H2O = phosphatidylinositol + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: inositol phosphate(n) + H2O = inositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from an inositol phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "inositol phosphate phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.195"^^xsd:string) Annotation( ) "sinapyl-alcohol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sinapyl alcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "MetaCyc:RXN-1125"^^xsd:string) "Catalysis of the reaction: sinapaldehyde + NADPH + H+ = sinapyl-alcohol + NADP+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.195"^^xsd:string) "sinapyl-alcohol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "baicalin beta-D-glucuronidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.167"^^xsd:string) "5,6,7-trihydroxyflavone-7-O-beta-D-glucupyranosiduronate glucuronosylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "RHEA:28133"^^xsd:string) "Catalysis of the reaction: baicalin + H2O = baicalein + D-glucuronate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.167"^^xsd:string) "baicalinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.98.2"^^xsd:string) Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "RHEA:27297"^^xsd:string) "Catalysis of the reaction: beta-D-glucose 6-phosphate + coenzyme F420 + H+ = 6-O-phosphono-D-glucono-1,5-lactone + reduced coenzyme F420."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.98.2"^^xsd:string) "F420-dependent glucose-6-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.98.2"^^xsd:string) "coenzyme F420-dependent glucose-6-phosphate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.98.2"^^xsd:string) Annotation( ) "D-glucose-6-phosphate:F420 1-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucose-6-phosphate dehydrogenase (coenzyme F420) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "KEGG:R07612"^^xsd:string) Annotation( "MetaCyc:RXN-8666"^^xsd:string) "Catalysis of the reaction: reactive black 5 + hydrogen peroxide = oxidized reactive black 5 + 2 H2O."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.11.1.16"^^xsd:string) "versatile peroxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "reactive-black-5:hydrogen-peroxide oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16766526"^^xsd:string) "Catalysis of the reaction: GDP-mannose + H2O = GMP + mannose-1-phosphate."^^xsd:string) AnnotationAssertion(Annotation( "PMID:16766526"^^xsd:string) "GDP-mannose pyrophosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "GDP-mannose hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:9914308"^^xsd:string) "Catalysis of the reaction: reduced coenzyme F420 + CoB-S-S-CoM = coenzyme F420 + CoM-SH + CoB-SH."^^xsd:string) AnnotationAssertion(Annotation( "PMID:9914308"^^xsd:string) "F420-dependent heterodisulfide oxidoreductase activity"^^xsd:string) AnnotationAssertion( "F420H2:heterodisulfide oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "reduced coenzyme F420:heterodisulfide oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9914308"^^xsd:string) "coenzyme F420-dependent heterodisulfide oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "isopropanol:coenzyme F420 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:15016352"^^xsd:string) Annotation( "PMID:1879431"^^xsd:string) Annotation( "PMID:8706724"^^xsd:string) "Catalysis of the reaction: propan-2-ol + coenzyme F420 = acetone + reduced coenzyme F420."^^xsd:string) AnnotationAssertion( "F420-dependent secondary alcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "propan-2-ol:coenzyme F420 oxidoreductase activity"^^xsd:string) AnnotationAssertion( "F420-dependent propan-2-ol dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "MetaCyc:MONOMER-13942"^^xsd:string) Annotation( "MetaCyc:RXN-9385"^^xsd:string) "Catalysis of the reaction: GTP + factor gamma-F420-2 + H+ = coenzyme F390-G + diphosphate."^^xsd:string) AnnotationAssertion( "GTP:coenzyme F420 guanylyltransferase activity"^^xsd:string) AnnotationAssertion( "coenzyme F390-G synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "GTP:coenzyme F420 guanyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "F420H2:2,3-dimethyl-1,4-naphthoquinone oxidoreductase activity"^^xsd:string) AnnotationAssertion( "F420H2-dependent quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion( "F420H2:quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:10971593"^^xsd:string) Annotation( "PMID:8055920"^^xsd:string) "Catalysis of the reaction: reduced coenzyme F420 + 2,3-dimethyl-1,4-naphthoquinone = coenzyme F420 + reduced 2,3-dimethyl-1,4-naphthoquinone. Reduced 2,3-dimethyl-1,4-naphthoquinone is also known as 2,3-dimethyl-1,4-hydronaphthoquinone."^^xsd:string) AnnotationAssertion(rdfs:label "reduced coenzyme F420:quinone oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:15274915"^^xsd:string) Annotation( "Wikipedia:chitobiose"^^xsd:string) "Catalysis of the reaction: chitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate. This reaction is the phosphorolysis of chitobiose, (GlcNAc)2, a dimer of beta-(1->4) linked glucosamine units."^^xsd:string) AnnotationAssertion(rdfs:label "chitobiose phosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chondroitin hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:18390555"^^xsd:string) "Catalysis of the hydrolysis of hexosaminic linkages in chondroitin, a linear polymer structure composed of the repeating disaccharide unit [->4)-D-glucuronic acid-(1->3)-N-acetyl-D-galactosamine-(1-], also written as [->4GlcUA1->3GalNAc1-]."^^xsd:string) AnnotationAssertion(Annotation( "PMID:18390555"^^xsd:string) "chondroitin endo-beta-galactosaminidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "TNP reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:11995829"^^xsd:string) Annotation( "UM-BBD_reactionID:r1065"^^xsd:string) "Catalysis of the reaction: 2,4,6-trinitrophenol + H- = 2,4,6-trinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction."^^xsd:string) AnnotationAssertion( "coenzyme F420-dependent 2,4,6-trinitrophenol hydride transferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "UM-BBD_reactionID:r1066"^^xsd:string) "Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex + H- = trinitrophenol dihydride Meisenheimer complex (aci form). Coenzyme F420 supplies the hydride (H-) in the reaction."^^xsd:string) AnnotationAssertion( "coenzyme F420-dependent 2,4,6-trinitrophenol-hydride-Meisenheimer-complex hydride transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "coenzyme F420-dependent 2,4-dinitrophenol reductase activity"^^xsd:string) AnnotationAssertion( "DNP reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:11995829"^^xsd:string) Annotation( "UM-BBD_reactionID:r1071"^^xsd:string) "Catalysis of the reaction: 2,4-dinitrophenol + H- = 2,4-dinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction."^^xsd:string) AnnotationAssertion( "coenzyme F420-dependent 2,4-dinitrophenol hydride transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.165"^^xsd:string) "exochitosanase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R08715"^^xsd:string) "chitosan glucosaminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.165"^^xsd:string) Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "MetaCyc:3.2.1.165-RXN"^^xsd:string) "Catalysis of the reaction: [beta-(1->4)-D-glucosamine]n-[N-acetyl-D-glucosamine]m = D-glucosamine + [beta-(1->4)-D-glucosamine](n-1)-[N-acetyl-D-glucosamine]m. This reaction is the hydrolysis of chitosan or chitosan oligosaccharides to remove a D-glucosamine residue from the non-reducing termini; chitosan is a linear polysaccharide composed of randomly distributed beta-(1->4)-linked D-glucosamine and N-acetyl-D-glucosamine units."^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R08715"^^xsd:string) "chitosan exo-1,4-beta-D-glucosaminidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "exo-1,4-beta-D-glucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.165"^^xsd:string) "exo-beta-D-glucosaminidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "MetaCyc:RXN-12269"^^xsd:string) "Catalysis of the reaction: gellan = n beta-D-4-deoxy-delta4,5-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp. This reaction is the eliminative cleavage of beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyluronate bonds of gellan backbone, releasing tetrasaccharides containing a 4-deoxy-4,5-unsaturated D-glucopyranosyluronic acid at the non-reducing end; in the product, the abbreviations are D-glucose (Glc), D-glucuronic acid (GlcA), and L-rhamnose (Rha)."^^xsd:string) AnnotationAssertion(rdfs:label "gellan lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ulvan lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:9468631"^^xsd:string) "Catalysis of the cleavage of a carbon-oxygen bond in ulvan, a carbohydrate composed of a repeating structure of [->4)-beta-D-GlcA-(1,4)-alpha-L-Rha 3S-(1->4)-alpha-L-IdoA-(1->4)-alpha-L-Rha 3S-(1-]n. Continued digest of ulvan with an enzyme that can catalyze this reaction results in ulvanobiouronic acid A 3-sulfate [->4)-beta-D-GlcpA-(1->4)-alpha-L-Rhap 3-sulfate-(1-]n with 4-deoxy-L-threo-hex-4-enopyranosiduronic acid at the non-reducing end."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "exo-oligoalginate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:20925655"^^xsd:string) "Catalysis of the cleavage of glycosidic bonds through a beta-elimination reaction on alginate, a linear polysaccharide consisting of guluronate (G) and mannuronate (M) as the monomer constituents. An oligoalginate is a linear polymer of two, three or four units of (1->4)-alpha-L-guluronic acid and beta-D-mannuronic acid, releasing monosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "F420H2:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion( "F420H2 oxidase activity"^^xsd:string) AnnotationAssertion( "coenzyme F420H2 oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:15340796"^^xsd:string) "Catalysis of the reaction: 2 reduced coenzyme F420 + O2 = 2 coenzyme F420 + 2 H2O."^^xsd:string) AnnotationAssertion(rdfs:label "reduced coenzyme F420 oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mannoside alpha-1,4-mannosidase activity"^^xsd:string) AnnotationAssertion( "mannoside exo-alpha-1,4-mannosidase activity"^^xsd:string) AnnotationAssertion( "alpha-1,4-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:20081828"^^xsd:string) "Catalysis of the hydrolysis of the alpha-(1->4) linkage of the terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides."^^xsd:string) AnnotationAssertion( "alpha-1,4-exomannosidase activity"^^xsd:string) AnnotationAssertion( "mannoside alpha-1,4-exomannosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "1,6-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannosyl-oligosaccharide 1,6-alpha-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:1849817"^^xsd:string) Annotation( "PMID:2338081"^^xsd:string) "Catalysis of the hydrolysis of the alpha-(1->6) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide."^^xsd:string) AnnotationAssertion( "alpha-1,6-mannosyl-oligosaccharide alpha-D-mannohydrolase activity"^^xsd:string) AnnotationAssertion( "1,6-alpha-mannosidase activity"^^xsd:string) AnnotationAssertion( "alpha-1,6-mannosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "1,3-alpha-mannosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:1849817"^^xsd:string) Annotation( "PMID:2338081"^^xsd:string) "Catalysis of the hydrolysis of the alpha-(1->3) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide."^^xsd:string) AnnotationAssertion( "1,3-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity"^^xsd:string) AnnotationAssertion( "alpha-1,3-mannosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "mannosyl-oligosaccharide 1,3-alpha-mannosidase activity"^^xsd:string) AnnotationAssertion( "alpha-1,3-mannosyl-oligosaccharide alpha-D-mannohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sulfomucin beta-6-sulfate-N-acetylglucosaminidase activity"^^xsd:string) AnnotationAssertion( "sulfoglycosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-6-sulfate-N-acetylglucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:15716424"^^xsd:string) "Catalysis of the glycosidic cleavage of the terminal 2-acetamido-2-deoxy-beta-D-glucopyranoside 6-sulfate (6-SO3-GlcNAc) residue from sulfomucin, a sulfated mucin derivative."^^xsd:string) AnnotationAssertion( "exosulfoglycosidase activity"^^xsd:string) AnnotationAssertion( "beta-6-SO3-N-acetylglucosaminidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "8-hydroxyadenylylated-coenzyme F420 hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "coenzyme F390-A hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:8536708"^^xsd:string) Annotation( "PMID:9352911"^^xsd:string) "Catalysis of the reaction: coenzyme F390-A = AMP + coenzyme F420."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "coenzyme F390-G hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:8536708"^^xsd:string) Annotation( "PMID:9352911"^^xsd:string) "Catalysis of the reaction: coenzyme F390-G = GMP + coenzyme F420."^^xsd:string) AnnotationAssertion( "8-hydroxyguanylylated-coenzyme F420 hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:10201402"^^xsd:string) Annotation( "PMID:8106385"^^xsd:string) "Catalysis of the hydrolysis of brefeldin A to produce brefeldin A acid. Brefeldin A is also known as gamma,4-dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid lambda-lactone."^^xsd:string) AnnotationAssertion( "BFA esterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "brefeldin A esterase activity"^^xsd:string) AnnotationAssertion( "brefeldin A hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "MetaCyc:RXN-12543"^^xsd:string) Annotation( "PMID:15136574"^^xsd:string) Annotation( "PMID:16232910"^^xsd:string) Annotation( "PMID:16736587"^^xsd:string) "Catalysis of the reaction: N,N'-diacetylchitobiose (GlcNac2) + H2O = acetate + 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose (GlcN-GlcNAc)."^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-12543"^^xsd:string) "N,N'-diacetylchitobiose deacetylase (nonreducing end)"^^xsd:string) AnnotationAssertion(rdfs:label "diacetylchitobiose deacetylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucosyl-N-acetylglucosamine glucosaminidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:15136574"^^xsd:string) Annotation( "PMID:16232910"^^xsd:string) Annotation( "PMID:16736587"^^xsd:string) "Catalysis of the reaction: glucosyl-N-acetylglucosamine + H2O = glucosamine + N-acetylglucosamine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "endorhamnosidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "endo-1,3-alpha-L-rhamnosidase activity"^^xsd:string) AnnotationAssertion( "endo-(1->3)-alpha-L-rhamnosidase activity"^^xsd:string) AnnotationAssertion( "endo-(1,3)-alpha-L-rhamnosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:10439404"^^xsd:string) "Catalysis of the reaction: R1-L-rhamnose-(1->3)-alpha-L-rhamnose-R2 + H2O = R1-L-rhamnose + L-rhamnose-R2. This reaction is the hydrolysis of an alpha-(1->3) linkage between two rhamnose residues in a polysaccharide chain."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "d-4,5 unsaturated beta-glucuronyl hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:12729728"^^xsd:string) "Catalysis of the hydrolysis of the glycosidic bond in an unsaturated saccharide between the unsaturated glucuronyl residue at the nonreducing terminus and the saccharide linked to the residue."^^xsd:string) AnnotationAssertion( "unsaturated beta-glucuronyl hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.78"^^xsd:string) "beta-1,3-mannan 3-mannanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.78"^^xsd:string) "1,3-beta-D-mannan mannanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.78"^^xsd:string) "exo-1,3-mannanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.78"^^xsd:string) "exo-beta-1,3-mannase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.78"^^xsd:string) "exo-1,3-beta-mannanase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.78"^^xsd:string) Annotation( "GOC:mengo_curators"^^xsd:string) "Catalysis of the hydrolysis of (1->3)-beta-D-mannosidic linkages in mannans, releasing mannose."^^xsd:string) AnnotationAssertion(rdfs:label "mannan 1,3-beta-mannosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:8421697"^^xsd:string) Annotation( "PMID:8986807"^^xsd:string) "Catalysis of the reaction: chitooligosaccharide with N-acetylglucosamine at nonreducing terminal + H2O = chitooligosaccharide with glucosamine at nonreducing terminal + acetate. This reaction is the deacetylation of a chitooligosaccharide at the nonreducing N-acetylglucosamine residue; chitooligosaccharide are composed of (1->4)-linked D-glucosamine (GlcN) and N-acetyl-D-glucosamine (GlcNAc) in varying proportions."^^xsd:string) AnnotationAssertion(rdfs:label "chitooligosaccharide deacetylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-deoxy-D-glycero-D-galacto-2-nonulosonic acid hydrolase activity"^^xsd:string) AnnotationAssertion( "2-keto-3-deoxynononic acid sialidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:21247893"^^xsd:string) "Catalysis of the reaction: (2-keto-3-deoxynononic acid)n + H2O = (2-keto-3-deoxynononic acid)n-1 + 2-keto-3-deoxynononic acid. This reaction is the hydrolysis of a 2-keto-3-deoxynononic acid residue from a poly-2-keto-3-deoxynononic acid chain."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:10618200"^^xsd:string) "Catalysis of the endohydrolysis of xylogalacturonate by cleavage of the alpha-(1,4)-linkage. Xylogalacturonate (XGA) is composed of a chain of alpha-(1,4)-linked D-galacturonic acid residues with beta-D-xylose substituted at the O3 position."^^xsd:string) AnnotationAssertion(rdfs:label "endo-xylogalacturonan hydrolase activity"^^xsd:string) AnnotationAssertion( "endo-galacturonase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:9218776"^^xsd:string) "Catalysis of the reaction: pectin + H2O = pectate + acetate. This reaction is the hydrolysis of acetyl esters of pectin, producing pectate, partially esterified pectin."^^xsd:string) AnnotationAssertion(rdfs:label "pectin acetylesterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.18"^^xsd:string) Annotation( "GOC:mengo_curators"^^xsd:string) "Catalysis of the hydrolysis of alpha-(2->3)-glycosidic linkages of terminal sialic residues in substrates."^^xsd:string) AnnotationAssertion( "exo-alpha-2,3-sialidase activity"^^xsd:string) AnnotationAssertion( "exo-alpha-(2,3)-sialidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "exo-alpha-(2->3)-sialidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "exo-alpha-2,6-sialidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "exo-alpha-(2->6)-sialidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.18"^^xsd:string) Annotation( "GOC:mengo_curators"^^xsd:string) "Catalysis of the hydrolysis of alpha-(2->6)-glycosidic linkages of terminal sialic residues in substrates."^^xsd:string) AnnotationAssertion( "exo-alpha-(2,6)-sialidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.18"^^xsd:string) Annotation( "GOC:mengo_curators"^^xsd:string) "Catalysis of the hydrolysis of alpha-(2->8)-glycosidic linkages of terminal sialic residues in substrates."^^xsd:string) AnnotationAssertion( "exo-alpha-2,8-sialidase activity"^^xsd:string) AnnotationAssertion( "exo-alpha-(2,8)-sialidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "exo-alpha-(2->8)-sialidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16876163"^^xsd:string) "glucuronoyl esterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-O-methyl-glucuronoyl methylesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:16876163"^^xsd:string) "Catalysis of the reaction: [X]-4-O-methyl-D-glucuronic acid + H2O = [X]-OH + methyl-D-glucuronic acid. This reaction is the hydrolysis of the ester linkage between 4-O-methyl-D-glucuronic acid (MeGlcA) and an alcohol (-OH) group attached to a molecule, denoted here as [X]."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-galactoside alpha-2,3-sialyltransferase activity"^^xsd:string) AnnotationAssertion( "trans-sialidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:7826016"^^xsd:string) Annotation( "PMID:8405811"^^xsd:string) "Catalysis of the transfer of sialyl residues alpha-2,3-linked to a beta galactosyl residue on the donor to form an alpha-2,3 linkage to a terminal beta galactosyl residue on the acceptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "sulfite:reduced coenzyme F420 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:16048999"^^xsd:string) "Catalysis of the reaction: sulfite + 3 1,5-dihydrocoenzyme F420 = hydrogen sulfide + 3 H2O + 3 coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420."^^xsd:string) AnnotationAssertion( "coenzyme F420-sulfite reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfite reductase (coenzyme F420) activity"^^xsd:string) AnnotationAssertion( "hydrogen-sulfide:coenzyme F420 oxidoreductase activity"^^xsd:string) AnnotationAssertion( "coenzyme F420-dependent sulfite reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "coenzyme F420-dependent aflatoxin reductase activity"^^xsd:string) AnnotationAssertion( "aflatoxin:reduced coenzyme F420 reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:20807200"^^xsd:string) "Catalysis of the reaction: aflatoxin + 1,5-dihydrocoenzyme F420 = aflatoxin with reduced furanocoumarin moiety + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420."^^xsd:string) AnnotationAssertion( "aflatoxin:coenzyme F420 oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aflatoxin reductase (coenzyme F420) activity"^^xsd:string) AnnotationAssertion( "coenzyme F420-aflatoxin reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "F420H2:NADP oxidoreductase activity"^^xsd:string) AnnotationAssertion( "coenzyme F420-dependent NADP reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:11726492"^^xsd:string) "Catalysis of the reaction: NADP+ + 1,5-dihydrocoenzyme F420 = NADPH + H+ + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420."^^xsd:string) AnnotationAssertion(rdfs:label "reduced coenzyme F420:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion( "F420H2:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion( "NADP+:F420 oxidoreductase activity"^^xsd:string) AnnotationAssertion( "coenzyme F420-dependent NADP oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acharan sulfate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) Annotation( "PMID:19566715"^^xsd:string) "Catalysis of the cleavage of a carbon-oxygen bond in acharan sulfate, a glycosaminoglycan with a uniformly repeating disaccharide structure of alpha-D-N-acetylglucosaminyl-2-O-sulfo-alpha-L-iduronic acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.137"^^xsd:string) "ATP:1-phosphatidyl-1D-myo-inositol 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion( "1-phosphatidylinositol 5-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.137"^^xsd:string) "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "1-phosphatidylinositol-5-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.150"^^xsd:string) "Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.150"^^xsd:string) "ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 4-phosphotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "1-phosphatidylinositol-3-phosphate 4-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.150"^^xsd:string) "phosphatidylinositol 3-phosphate 4-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.7.1.153"^^xsd:string) "ATP:1-phosphatidyl-1D-myo-inositol-3,4-bisphosphate 5-phosphotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.153"^^xsd:string) "Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol-3,4-bisphosphate 5-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: ATP + a phosphatidylinositol bisphosphate = ADP + a phosphatidylinositol trisphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol bisphosphate kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "medium-chain-aldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.48"^^xsd:string) "medium-chain-aldehyde:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.48"^^xsd:string) "medium-chain fatty aldehyde dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.48"^^xsd:string) "Catalysis of the reaction: a medium-chain aldehyde + NAD+ = a medium-chain carboxylate + NADH + H+. Medium-chain aldehydes have a chain length of between 8 and 12 carbons."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.2.1.48"^^xsd:string) "medium-chain aliphatic aldehyde dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "medium-chain acyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "medium-chain-acyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "medium-chain acyl coenzyme A hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "medium-chain acyl-thioester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "medium-chain hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA. A medium chain is a chain of between eight and twelve carbons in length."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "long-chain acyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "long-chain acyl coenzyme A hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "long-chain hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "long-chain acyl-thioester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "long-chain-acyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "Catalysis of the reaction: H2O + a long-chain acyl-CoA = a long-chain carboxylate + CoA. A long chain is a chain of greater than 12 carbons in length."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "very long-chain hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "very long-chain-acyl-CoA hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "very long-chain acyl-thioester hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "very long-chain acyl coenzyme A hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.2.19"^^xsd:string) "Catalysis of the reaction: H2O + a very long chain acyl-CoA = a very long chain carboxylate + CoA. A very long chain has chain length greater than C18."^^xsd:string) AnnotationAssertion(rdfs:label "very long chain acyl-CoA hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.48"^^xsd:string) "GDP-mannose:heteroglycan 3-alpha-D-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.48"^^xsd:string) "GDP mannose 3-alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.48"^^xsd:string) Annotation( "MetaCyc:RXN-7992"^^xsd:string) "Catalysis of the reaction: heteroglycan + GDP-mannose = (1->3)-alpha-D-mannosylheteroglycan + GDP."^^xsd:string) AnnotationAssertion(rdfs:label "heteroglycan 3-alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "heteropolysaccharide 3-alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.48"^^xsd:string) "guanosine diphosphomannose-heteroglycan 3-alpha-mannosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "heteropolysaccharide 2-alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.48"^^xsd:string) "GDP-mannose:heteroglycan 2-alpha-D-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.48"^^xsd:string) "guanosine diphosphomannose-heteroglycan 2-alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "heteroglycan 2-alpha-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.48"^^xsd:string) Annotation( "MetaCyc:2.4.1.48-RXN"^^xsd:string) "Catalysis of the reaction: heteroglycan + GDP-mannose = (1->2)-alpha-D-mannosylheteroglycan + GDP."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.48"^^xsd:string) "GDP mannose 2-alpha-mannosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "1,N(6)-ethenoadenine N-glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:21960007"^^xsd:string) "Catalysis of the reaction: DNA with 1-N6-ethenoadenine + H2O = DNA with abasic site + 1-N6-ethenoadenine. This reaction is the removal of 1,N6-ethenoadenine by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar."^^xsd:string) AnnotationAssertion(rdfs:label "DNA-1,N6-ethenoadenine N-glycosylase activity"^^xsd:string) AnnotationAssertion( "1,N6-ethenoadenine glycosylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) Annotation( "PMID:16468998"^^xsd:string) "Catalysis of the reaction: DNA containing 7-methyladenine + H2O = DNA with abasic site + 7-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methyladenine and the deoxyribose sugar to remove the 7-methyladenine, leaving an abasic site."^^xsd:string) AnnotationAssertion(rdfs:label "DNA-7-methyladenine glycosylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.2.20"^^xsd:string) "3-methylguanine DNA glycosylase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.20"^^xsd:string) "alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)"^^xsd:string) AnnotationAssertion(rdfs:label "DNA-3-methylguanine glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.20"^^xsd:string) "deoxyribonucleate 3-methylguanine glycosidase I"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.20"^^xsd:string) "DNA glycosidase I activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.2.21"^^xsd:string) Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:10872450"^^xsd:string) Annotation( "PMID:9224623"^^xsd:string) "Catalysis of the reaction: DNA containing 3-methylguanine + H2O = DNA with abasic site + 3-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylguanine and the deoxyribose sugar to remove the 3-methylguanine, leaving an abasic site."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.7.1.14"^^xsd:string) Annotation( ) "(2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate fumarylhydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:25049"^^xsd:string) "Catalysis of the reaction: (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + fumarate + H+."^^xsd:string) AnnotationAssertion(Annotation( "UM-BBD_reactionID:r1622"^^xsd:string) "2-hydroxy-6-ketonona-2,4,7-trienedoic acid hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10336995"^^xsd:string) "Catalysis of the addition of mannose to dolichyl-pyrophosphate Man7GlcNAc2 (also written as Man7GlcNAc2-PP-Dol) in alpha-(1->6) linkage, producing Man8GlcNAc2-PP-Dol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-3,4,5,6-tetrakisphosphate + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol hexakisphosphate 2-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.62"^^xsd:string) "Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.62"^^xsd:string) "1D-myo-inositol-hexakisphosphate 2-phosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol pentakisphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "Catalysis of the reaction: myo-inositol pentakisphosphate + H2O = myo-inositol tetrakisphosphate + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol-3,4-bisphosphate 4-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: 1D-myo-inositol 3,4-bisphosphate + H2O = 1D-myo-inositol 3-phosphate + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol-1,3,4-trisphosphate 1-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-1,3,4-trisphosphate + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-3,4,6-trisphosphate + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol monophosphate 3-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "Catalysis of the reaction: myo-inositol 3-phosphate + H2O = myo-inositol + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "myo-inositol-1(or 4)-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "inositol-1(or 4)-monophosphatase activity"^^xsd:string) AnnotationAssertion( "myo-inositol-1(or 4)-monophosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol monophosphate 4-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "Catalysis of the reaction: myo-inositol 4-phosphate + H2O = myo-inositol + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "inositol-1(or 4)-monophosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol monophosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "myo-inositol monophosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "L-myo-inositol-phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "myo-inositol-1(or 4)-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "myo-inositol-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "inositol phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "inositol-phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "myo-inositol phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "Catalysis of the reaction: myo-inositol phosphate + H2O = myo-inositol + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.25"^^xsd:string) "myo-inositol-phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "inositol 3,4,6-trisphosphate 1-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.127"^^xsd:string) "IP3 1-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.127"^^xsd:string) "Ins(3,4,6)P3 1-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.127"^^xsd:string) "ATP:1D-myo-inositol-3,4,6-trisphosphate 1-phosphotransferase activity"^^xsd:string) AnnotationAssertion( "1D-myo-inositol-trisphosphate 1-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.127"^^xsd:string) "ins(3,4,6)P(3) 1-kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.7.1.134"^^xsd:string) "Catalysis of the reaction: 1D-myo-inositol 3,4,6-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+)."^^xsd:string) AnnotationAssertion(rdfs:label "inositol-3,4,6-trisphosphate 1-kinase activity"^^xsd:string) AnnotationAssertion( "inositol-trisphosphate 1-kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11502751"^^xsd:string) Annotation( "PMID:18355727"^^xsd:string) "Catalysis of the reaction: ATP + inositol 5-diphosphate pentakisphosphate = ADP + inositol 5-triphosphate pentakisphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "inositol 5-diphosphate pentakisphosphate 5-kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol diphosphate tetrakisphosphate kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:10827188"^^xsd:string) Annotation( "PMID:11502751"^^xsd:string) Annotation( "PMID:18355727"^^xsd:string) "Catalysis of the reaction: Catalysis of the reaction: ATP + inositol diphosphate tetrakisphosphate = ADP + inositol bisdiphosphate trisphosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol diphosphate tetrakisphosphate diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10963"^^xsd:string) Annotation( "PMID:10827188"^^xsd:string) Annotation( "PMID:11502751"^^xsd:string) "Catalysis of the reaction: inositol diphosphate tetrakisphosphate + H2O = inositol 1,3,4,5,6-pentakisphosphate + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-10965"^^xsd:string) Annotation( "MetaCyc:RXN-10975"^^xsd:string) Annotation( "MetaCyc:RXN-10976"^^xsd:string) Annotation( "PMID:10827188"^^xsd:string) Annotation( "PMID:11502751"^^xsd:string) "Catalysis of the reaction: inositol bisdiphosphate tetrakisphosphate + H2O = inositol diphosphate pentakisphosphate + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "inositol bisdiphosphate tetrakisphosphate diphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol diphosphate pentakisphosphate diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10964"^^xsd:string) Annotation( "MetaCyc:RXN-10977"^^xsd:string) Annotation( "MetaCyc:RXN-10978"^^xsd:string) Annotation( "PMID:10827188"^^xsd:string) Annotation( "PMID:11502751"^^xsd:string) "Catalysis of the reaction: inositol diphosphate pentakisphosphate + H2O = inositol hexakisphosphate + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-10977"^^xsd:string) Annotation( "PMID:10827188"^^xsd:string) Annotation( "PMID:11502751"^^xsd:string) "Catalysis of the reaction: inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+."^^xsd:string) AnnotationAssertion(rdfs:label "inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10978"^^xsd:string) Annotation( "PMID:10827188"^^xsd:string) Annotation( "PMID:11502751"^^xsd:string) "Catalysis of the reaction: inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-10964"^^xsd:string) Annotation( "PMID:10827188"^^xsd:string) Annotation( "PMID:11502751"^^xsd:string) "Catalysis of the reaction: inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+."^^xsd:string) AnnotationAssertion(rdfs:label "inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10965"^^xsd:string) Annotation( "PMID:10827188"^^xsd:string) Annotation( "PMID:11502751"^^xsd:string) "Catalysis of the reaction: 1,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10975"^^xsd:string) Annotation( "PMID:10827188"^^xsd:string) Annotation( "PMID:11502751"^^xsd:string) "Catalysis of the reaction: 1,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + phosphate + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10976"^^xsd:string) Annotation( "PMID:10827188"^^xsd:string) Annotation( "PMID:11502751"^^xsd:string) "Catalysis of the reaction: 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NADPH-dependent curcumin reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-6676"^^xsd:string) "Catalysis of the reaction: curcumin + NADPH + H+ = dihydrocurcumin + NADP+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "dihydrocurcumin reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-6677"^^xsd:string) "Catalysis of the reaction: dihydrocurcumin + NADPH+ + H+ = tetrahydrocurcumin + NADP+."^^xsd:string) AnnotationAssertion(rdfs:label "NADPH-dependent dihydrocurcumin reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Fe(II):NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-6555"^^xsd:string) "Catalysis of the reaction: 2 Fe3+ + NADPH = 2 Fe2+ + H+ + NADP+ ."^^xsd:string) AnnotationAssertion( "NADPH:Fe3+-EDTA reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ferric-chelate reductase (NADPH) activity"^^xsd:string) AnnotationAssertion( "ferric chelate reductase activity"^^xsd:string) AnnotationAssertion( "ferric reductase, NADPH-dependent activity"^^xsd:string) AnnotationAssertion( "iron chelate reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "oxidase, very-long-chain L-2-hydroxy acid"^^xsd:string) AnnotationAssertion(rdfs:label "very-long-chain-(S)-2-hydroxy-acid oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "very-long-chain-hydroxy-acid oxidase A activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "very-long-chain-hydroxy-acid oxidase B activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "Catalysis of the reaction: very-long-chain (S)-2-hydroxy-acid + O2 = very-long-chain 2-oxo acid + hydrogen peroxide. Very long chain refers to a chain length of greater than 18 carbons."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "very-long-chain-(S)-2-hydroxy-acid:oxygen 2-oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "very-long-chain L-alpha-hydroxy acid oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "very-long-chain-hydroxyacid oxidase A"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "very-long-chain L-2-hydroxy acid oxidase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "long-chain-hydroxyacid oxidase A"^^xsd:string) AnnotationAssertion(rdfs:label "long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "Catalysis of the reaction: long-chain-(S)-2-hydroxy-acid + O2 = long-chain-2-oxo acid + hydrogen peroxide. Long chain refers to a chain length of 14 to 18 carbons."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "long-chain-L-alpha-hydroxy acid oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "long-chain-hydroxy-acid oxidase A activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "long-chain-L-2-hydroxy acid oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "long-chain-hydroxy-acid oxidase B activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "oxidase, long-chain-L-2-hydroxy acid"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "long-chain-(S)-2-hydroxy-acid:oxygen 2-oxidoreductase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "oxidase, medium-chain-L-2-hydroxy acid"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "medium-chain-hydroxy-acid oxidase B activity"^^xsd:string) AnnotationAssertion(rdfs:label "medium-chain-(S)-2-hydroxy-acid oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "Catalysis of the reaction: medium-chain-(S)-2-hydroxy-acid + O2 = medium-chain-2-oxo acid + hydrogen peroxide. Medium chain refers to a chain length of between 8 and 12 carbons."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "medium-chain-(S)-2-hydroxy-acid:oxygen 2-oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "medium-chain-hydroxyacid oxidase A"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "medium-chain-L-2-hydroxy acid oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "medium-chain-L-alpha-hydroxy acid oxidase"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.3.15"^^xsd:string) "medium-chain-hydroxy-acid oxidase A activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ADP-dependent NAD(P)H-hydrate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.93"^^xsd:string) Annotation( "PMID:21994945"^^xsd:string) "Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ADP = AMP + 3 H(+) + NADH + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.93"^^xsd:string) "(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase(ADP-hydrolysing; NADH-forming)"^^xsd:string) AnnotationAssertion( "ADP-dependent H4NAD(P)OH dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.93"^^xsd:string) "reduced nicotinamide adenine dinucleotide hydrate dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.93"^^xsd:string) "(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing)"^^xsd:string) AnnotationAssertion( "ADP-dependent H(4)NAD(P)OH dehydratase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:21994945"^^xsd:string) "Catalysis of the reaction: (R)-NADHX = (S)-NADHX."^^xsd:string) AnnotationAssertion(rdfs:label "NADHX epimerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NADPHX epimerase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:21994945"^^xsd:string) "Catalysis of the reaction: (R)-NADPHX = (S)-NADPHX."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.3.1.32"^^xsd:string) "Catalysis of the reaction: acetyl phosphate + peptidyl-L-lysine = phosphate + peptidyl-N6-acetyl-L-lysine."^^xsd:string) AnnotationAssertion( "acetyl-phosphate:peptidyl-L-lysine 6-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion( "peptidyl-lysine N6-acetyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "peptidyl-lysine N-acetyltransferase activity"^^xsd:string) AnnotationAssertion( "peptidyl-lysine N(6)-acetyltransferase activity"^^xsd:string) AnnotationAssertion( "peptidyl-lysine acetyltransferase activity"^^xsd:string) AnnotationAssertion( "acetyl-phosphate:peptidyl-L-lysine N6-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "beta-1->4-glucan hydrolase activity"^^xsd:string) AnnotationAssertion( "beta-1,4-glucan hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.75"^^xsd:string) "Catalysis of the random hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans."^^xsd:string) AnnotationAssertion( "beta-1,4-glucan 4-glucanohydrolase activity"^^xsd:string) AnnotationAssertion( "endo-beta-1,4-glucanase activity"^^xsd:string) AnnotationAssertion( "endo-1,4-beta-glucanase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucan endo-1,4-beta-glucosidase activity"^^xsd:string) AnnotationAssertion( "endo-(1,4)-beta-D-glucanase activity"^^xsd:string) AnnotationAssertion( "endo-1,4-beta-D-glucanase activity"^^xsd:string) AnnotationAssertion( "1,4-beta-D-glucan glucanohydrolase activity"^^xsd:string) AnnotationAssertion( "endo-(1->4)-beta-D-glucanase activity"^^xsd:string) AnnotationAssertion( "beta-1,4-glucanase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.11.25"^^xsd:string) "Catalysis of the reaction: 2'-deoxymugineic acid + 2-oxoglutarate + O2 = 3-epihydroxy-2'-deoxymugineic acid + succinate + CO2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.25"^^xsd:string) "2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity"^^xsd:string) AnnotationAssertion(rdfs:label "2'-deoxymugineic-acid 3-dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.6"^^xsd:string) "Catalysis of the endohydrolysis of (1->3)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.6"^^xsd:string) "laminaranase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.6"^^xsd:string) "laminarinase activity"^^xsd:string) AnnotationAssertion(rdfs:label "glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.6"^^xsd:string) "1,3-(1,3)-beta-D-glucan 3-glucanohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.2.1.6"^^xsd:string) "laminaranase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.6"^^xsd:string) "1,3-(1,4)-beta-D-glucan 4-glucanohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.6"^^xsd:string) "laminarinase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.2.1.6"^^xsd:string) "Catalysis of the endohydrolysis of (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3."^^xsd:string) AnnotationAssertion(rdfs:label "glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of the reaction: phosphatidylinositol phosphate(n) + H2O = phosphatidylinositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from a phosphatidylinositol phosphate."^^xsd:string) AnnotationAssertion( "phosphoinositide phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol phosphate phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.3.-"^^xsd:string) "phosphatidylinositol 1,4,5-trisphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.-"^^xsd:string) "phosphatidyl-myo-inositol-1,4,5-trisphosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.-"^^xsd:string) "phosphatidylinositol-trisphosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.-"^^xsd:string) "triphosphoinositide phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.-"^^xsd:string) "triphosphoinositide phosphomonoesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.-"^^xsd:string) "PtdIns(1,4,5)P(3) phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.-"^^xsd:string) "Catalysis of the reaction: phosphatidyl-1D-myo-inositol 1,4,5-trisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 1,4-bisphosphate + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.3.-"^^xsd:string) "PtdIns(1,4,5)P3 phosphatase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein-lysine lysyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:20729861"^^xsd:string) "Catalysis of the reaction: protein-lysine + protein-lysine = protein N6-(lysyl)-L-lysine + protein. This reaction is the addition of lysine group from one protein to a lysine residue in a second protein, producing N6-(lysyl)-L-lysine."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "KEGG:R07041"^^xsd:string) "Catalysis of the reaction: arachidonic acid + O2 + NADPH + H+ = 20-HETE + NADP+ + H2O. Arachidonic acid is also known as (5Z,8Z,11Z,14Z)-icosatetraenoic acid, and 20-HETE is also known as (5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid."^^xsd:string) AnnotationAssertion( "arachidonic acid hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "arachidonic acid omega-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( ) "arachidonic acid:oxygen 1-oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-11003"^^xsd:string) "Catalysis of the reaction: tocopherol + O2 + NADPH + H+ = 13'-hydroxy-tocopherol + NADP+ + H2O ."^^xsd:string) AnnotationAssertion(rdfs:label "tocopherol omega-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( ) "tocopherol 13-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "alpha-tocopherol 13-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "alpha-tocopherol omega-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11003"^^xsd:string) "Catalysis of the reaction: alpha-tocopherol + O2 + NADPH + H+ = 13'-hydroxy-alpha-tocopherol + NADP+ + H2O ."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tocotrienol omega-hydroxylase activity"^^xsd:string) AnnotationAssertion( "tocotrienol 13-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-11003"^^xsd:string) "Catalysis of the reaction: tocotrienol + O2 + NADPH + H+ = 13'-hydroxy-tocotrienol + NADP+ + H2O ."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NADPH(2):FMN oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "FMNH2:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NADPH-FMN reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:21627"^^xsd:string) "Catalysis of the reaction: FMNH2 + NADP+ = FMN + NADPH + 2 H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NADPH(2) dehydrogenase (FMN) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NADPH:FMN oxidoreductase activity"^^xsd:string) AnnotationAssertion( "NADPH dehydrogenase (FMN) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "flavin mononucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NADPH:flavin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "flavine mononucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "SsuE"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NADPH2:FMN oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.3"^^xsd:string) "NADPH2 dehydrogenase (FMN)"^^xsd:string) AnnotationAssertion(rdfs:label "FMN reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NADPH-dependent FMN reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "FMN reductase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NADH-FMN reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "flavine mononucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "flavin mononucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NADH:FMN oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:21623"^^xsd:string) "Catalysis of the reaction: FMNH2 + NAD+ = FMN + NADH + 2 H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NADH-dependent FMN reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "SsuE"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NADH(2):FMN oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "FMNH2:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NADH(2) dehydrogenase (FMN) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.3"^^xsd:string) "NADH2 dehydrogenase (FMN)"^^xsd:string) AnnotationAssertion( "NADH dehydrogenase (FMN) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NADH:flavin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.29"^^xsd:string) "NADH2:FMN oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.1.41"^^xsd:string) "NAD(P)H:riboflavin oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.41"^^xsd:string) "NAD(P)H:FMN oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.41"^^xsd:string) "riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide) reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.41"^^xsd:string) "riboflavin mononucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.41"^^xsd:string) "flavine mononucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.41"^^xsd:string) "NAD(P)H2:FMN oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "riboflavin reductase (NADH) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.41"^^xsd:string) "flavin mononucleotide reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.41"^^xsd:string) "NAD(P)H2 dehydrogenase (FMN) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.41"^^xsd:string) "NAD(P)H-dependent FMN reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.41"^^xsd:string) "NAD(P)H-FMN reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:31458"^^xsd:string) "Catalysis of the reaction: reduced riboflavin + NAD+ = riboflavin + NADH + 2 H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.1.41"^^xsd:string) "riboflavine mononucleotide reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.4.9.1"^^xsd:string) "primary-amine:(acceptor) oxidoreductase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.9.1"^^xsd:string) "amine:(acceptor) oxidoreductase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.9.1"^^xsd:string) "primary-amine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R00606"^^xsd:string) "Catalysis of the reaction: methylamine + H2O + amicyanin = formaldehyde + ammonia + reduced amicyanin."^^xsd:string) AnnotationAssertion(rdfs:label "methylamine dehydrogenase (amicyanin) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.9.1"^^xsd:string) Annotation( ) "methylamine:amicyanin oxidoreductase (deaminating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.9.1"^^xsd:string) "methylamine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.9.1"^^xsd:string) "MADH activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.4.9.1"^^xsd:string) "amine dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ai"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and a copper protein is the acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.13.11.60"^^xsd:string) "7,8-linoleate diol synthase (bifunctional enzyme) activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:25398"^^xsd:string) "Catalysis of the reaction: O(2) + linoleate = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.60"^^xsd:string) "7,8-LDS (bifunctional enzyme) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.60"^^xsd:string) "5,8-linoleate diol synthase (bifunctional enzyme) activity"^^xsd:string) AnnotationAssertion(rdfs:label "linoleate 8R-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.44"^^xsd:string) "linoleate diol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.60"^^xsd:string) "5,8-LDS (bifunctional enzyme) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:5.4.4.6"^^xsd:string) "(8R,9Z,12Z)-8-hydroperoxy-9,12-octadecadienoate mutase ((7S,8S,9Z,12Z)-5,8-dihydroxy-9,12-octadecadienoate-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.4.4.6"^^xsd:string) "8-hydroperoxide isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.44"^^xsd:string) "linoleate diol synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "9,12-octadecadienoate 8-hydroperoxide 8S-isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:25402"^^xsd:string) "Catalysis of the reaction: (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate = (7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a copper protein."^^xsd:string) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on diphenols and related substances as donors, with copper protein as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.14.14.9"^^xsd:string) "p-hydroxyphenylacetate 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.9"^^xsd:string) "p-hydroxyphenylacetate hydroxylase (FAD) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.9"^^xsd:string) "p-hydroxyphenylacetate 3-hydroxylase (FAD) activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:30598"^^xsd:string) "Catalysis of the reaction: (4-hydroxyphenyl)acetate + FADH(2) + O(2) = 3,4-dihydroxyphenylacetate + FAD + H(+) + H(2)O."^^xsd:string) AnnotationAssertion(Annotation( ) "4-hydroxyphenylacetate,FADH:oxygen oxidoreductase (3-hydroxylating) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.9"^^xsd:string) "4 HPA 3-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4-hydroxyphenylacetate 3-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.9"^^xsd:string) "4-hydroxyphenylacetic acid-3-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.14.9"^^xsd:string) "p-hydroxyphenylacetate hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on phosphorus or arsenic in donors, with a copper protein as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a copper protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.1.23"^^xsd:string) "tyrase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.23"^^xsd:string) "TAL activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.1.23"^^xsd:string) "L-tyrosine ammonia-lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:24909"^^xsd:string) "Catalysis of the reaction: L-tyrosine = NH(4)(+) + trans-4-coumarate."^^xsd:string) AnnotationAssertion(rdfs:label "tyrosine ammonia-lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.64"^^xsd:string) "retinol isomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:31778"^^xsd:string) "Catalysis of the reaction: H(2)O + all-trans-retinyl palmitate = 11-cis-retinol + H(+) + palmitate."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.64"^^xsd:string) "all-trans-retinyl-palmitate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.64"^^xsd:string) "all-trans-retinol isomerase:hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.64"^^xsd:string) "retinoid isomerohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.1.64"^^xsd:string) "all-trans-retinol isomerase:hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.64"^^xsd:string) "retinoid isomerohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.64"^^xsd:string) "all-trans-retinylester 11-cis isomerohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:31774"^^xsd:string) "Catalysis of the reaction: H(2)O + all-trans-retinyl ester = 11-cis-retinol + fatty acid."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.64"^^xsd:string) "all-trans-retinyl ester acylhydrolase, 11-cis retinol forming activity"^^xsd:string) AnnotationAssertion(rdfs:label "all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.64"^^xsd:string) "retinol isomerase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.5.6"^^xsd:string) "zeta-carotene desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.5.6"^^xsd:string) "Catalysis of the reaction: 9,9'-di-cis-zeta-carotene + a quinone = 7,9,9'-tri-cis-neurosporene + a quinol."^^xsd:string) AnnotationAssertion(rdfs:label "9,9'-dicis-carotene:quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.5.6"^^xsd:string) "ZDS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.5.6"^^xsd:string) "9,9'-di-cis-zeta-carotene desaturase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.5.6"^^xsd:string) "9,9'-di-cis-zeta-carotene desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.5.6"^^xsd:string) "Catalysis of the reaction: 7,9,9'-tri-cis-neurosporene + a quinone = 7,9,7',9'-tetra-cis-lycopene + a quinol."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.5.6"^^xsd:string) "ZDS activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.5.6"^^xsd:string) "zeta-carotene desaturase activity"^^xsd:string) AnnotationAssertion(rdfs:label "7,9,9'-tricis-neurosporene:quinone oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.98.1"^^xsd:string) Annotation( "RHEA:30062"^^xsd:string) "Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.98.1"^^xsd:string) "DHodehase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.98.1"^^xsd:string) "DHOD activity"^^xsd:string) AnnotationAssertion(rdfs:label "dihydroorotate oxidase (fumarate) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.98.1"^^xsd:string) "dihydroorotate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.98.1"^^xsd:string) "dihydoorotic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.98.1"^^xsd:string) "DHOdase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.98.1"^^xsd:string) "dihydroorotate oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a flavin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.47"^^xsd:string) "(S)-oxynitrilase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.47"^^xsd:string) "oxynitrilase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.47"^^xsd:string) "(S)-cyanohydrin producing hydroxynitrile lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.47"^^xsd:string) "(S)-cyanohydrin carbonyl-lyase (cyanide forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.47"^^xsd:string) "Catalysis of the reaction: an aliphatic (S)-hydroxynitrile = an aliphatic aldehyde or ketone + cyanide."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.47"^^xsd:string) "hydroxynitrile lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.47"^^xsd:string) "(S)-selective hydroxynitrile lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aliphatic (S)-hydroxynitrile lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.47"^^xsd:string) "(S)-hydroxynitrile lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.47"^^xsd:string) "(S)-oxynitrilase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.47"^^xsd:string) "(S)-hydroxynitrile lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.47"^^xsd:string) Annotation( "KEGG:R09359"^^xsd:string) "Catalysis of the reaction: an aromatic (S)-hydroxynitrile = an aromatic aldehyde + cyanide."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.47"^^xsd:string) "oxynitrilase activity"^^xsd:string) AnnotationAssertion(rdfs:label "aromatic (S)-hydroxynitrile lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.47"^^xsd:string) "hydroxynitrile lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.47"^^xsd:string) "(S)-cyanohydrin producing hydroxynitrile lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.47"^^xsd:string) "(S)-cyanohydrin carbonyl-lyase (cyanide forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.47"^^xsd:string) "(S)-selective hydroxynitrile lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.14"^^xsd:string) "polyamine oxidase (propane-1,3-diamine-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10465"^^xsd:string) "Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N-(3-acetamidopropyl)-4-aminobutanal + propane-1,3-diamine + hydrogen peroxide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-10464"^^xsd:string) "Catalysis of the reaction: norspermine + oxygen + H2O = norspermidine + 3-aminopropanal + hydrogen peroxide."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.16"^^xsd:string) "norspermine oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "norspermine:oxygen oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.3.16"^^xsd:string) "N1-acetylspermine oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:POLYAMINE-OXIDASE-RXN"^^xsd:string) "Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N1-acetylspermidine + 3-aminopropanal + hydrogen peroxide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "spermidine oxidase (propane-1,3-diamine-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.14"^^xsd:string) "polyamine oxidase (propane-1,3-diamine-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.14"^^xsd:string) "spermidine:(acceptor) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:25823"^^xsd:string) "Catalysis of the reaction: H(2)O + O(2) + spermidine = 1,3-diaminopropane + 4-aminobutanal + H(2)O(2)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.15"^^xsd:string) "N(8)-acetylspermidine oxidase (propane-1,3-diamine-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:25975"^^xsd:string) "Catalysis of the reaction: H(2)O + N(8)-acetylspermidine + O(2) = 1,3-diaminopropane + 4-acetamidobutanal + H(2)O(2)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:25867"^^xsd:string) "Catalysis of the reaction: H(2)O + N(1)-acetylspermidine + O(2) = 1,3-diaminopropane + 4-acetamidobutanal + H(2)O(2)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "RHEA:25871"^^xsd:string) "Catalysis of the reaction: H(2)O + N(1),N(12)-diacetylspermine + O(2) = 3-acetamidopropanal + H(2)O(2) + N(1)-acetylspermidine."^^xsd:string) AnnotationAssertion(rdfs:label "N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.13"^^xsd:string) "N(1)-acetylpolyamine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.13"^^xsd:string) Annotation( "EC:1.5.3.17"^^xsd:string) "polyamine oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "RHEA:25827"^^xsd:string) "Catalysis of the reaction: H(2)O + O(2) + spermine = 1,3-diaminopropane + H(2)O(2) + N-(3-aminopropyl)-4-aminobutanal."^^xsd:string) AnnotationAssertion(rdfs:label "spermine oxidase (propane-1,3-diamine-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.14"^^xsd:string) "polyamine oxidase (propane-1,3-diamine-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.3.13"^^xsd:string) Annotation( "EC:1.5.3.17"^^xsd:string) "polyamine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.17"^^xsd:string) "non-specific polyamine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.16"^^xsd:string) "spermine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.13"^^xsd:string) "N(1)-acetylpolyamine oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "spermine:oxygen oxidoreductase (spermidine-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:25807"^^xsd:string) "Catalysis of the reaction: H(2)O + O(2) + spermine = 3-aminopropanal + H(2)O(2) + spermidine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.3.17"^^xsd:string) "non-specific polyamine oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:25811"^^xsd:string) "Catalysis of the reaction: H(2)O + O(2) + spermidine = 3-aminopropanal + H(2)O(2) + putrescine."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.13"^^xsd:string) Annotation( "EC:1.5.3.17"^^xsd:string) "polyamine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.13"^^xsd:string) "N(1)-acetylpolyamine oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.3.13"^^xsd:string) Annotation( "EC:1.5.3.17"^^xsd:string) "polyamine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.13"^^xsd:string) "N(1)-acetylpolyamine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:25803"^^xsd:string) "Catalysis of the reaction: H(2)O + N(1)-acetylspermine + O(2) = 3-acetamidopropanal + H(2)O(2) + spermidine."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.17"^^xsd:string) "non-specific polyamine oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.5.3.13"^^xsd:string) "N(1)-acetylpolyamine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:25815"^^xsd:string) "Catalysis of the reaction: H(2)O + N(1)-acetylspermidine + O(2) = 3-acetamidopropanal + H(2)O(2) + putrescine."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.13"^^xsd:string) Annotation( "EC:1.5.3.17"^^xsd:string) "polyamine oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.5.3.17"^^xsd:string) "non-specific polyamine oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tRNA (guanine(9)-N(1))-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.221"^^xsd:string) "tRNA (guanine-N(1)-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.221"^^xsd:string) "tRNA m(1)G(9)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.221"^^xsd:string) "tRNA m(1)G(9) Mtase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.221"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + guanine(9) in tRNA = N(1)-methylguanine(9) in tRNA + S-adenosyl-L-homocysteine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.221"^^xsd:string) "tRNA(m(1)G(9)/m(1)A(9))Mtase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.221"^^xsd:string) "tRNA(m(1)G(9)/m(1)A(9))-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tRNA (guanine(37)-N(1))-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.228"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + guanine(37) in tRNA = N(1)-methylguanine(37) in tRNA + S-adenosyl-L-homocysteine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.228"^^xsd:string) "transfer RNA (m(1)G(37)) methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.228"^^xsd:string) "tRNA-(N(1)G37) methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.228"^^xsd:string) "tRNA (m(1)G(37)) methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.181"^^xsd:string) "M(6)A(1618) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.181"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA."^^xsd:string) AnnotationAssertion(rdfs:label "23S rRNA (adenine(1618)-N(6))-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.181"^^xsd:string) "rRNA large subunit methyltransferase F activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.182"^^xsd:string) "Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-dimethyladenine(1519) in 16S rRNA."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.182"^^xsd:string) "S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.183"^^xsd:string) "M(6)(2)A dimethylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.183"^^xsd:string) "Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1779)/adenine(1780) in 18S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1779)/N(6)-dimethyladenine(1780) in 18S rRNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.184"^^xsd:string) "ermC 23S rRNA methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.184"^^xsd:string) "rRNA methyltransferase ermC' activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.184"^^xsd:string) "rRNA:m(6)A methyltransferase ermC' activity"^^xsd:string) AnnotationAssertion(rdfs:label "23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.184"^^xsd:string) "Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2085) in 23S rRNA = 2 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(2085) in 23S rRNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.187"^^xsd:string) "23S rRNA m(1)G(745) methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "23S rRNA (guanine(745)-N(1))-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.187"^^xsd:string) "ribosomal ribonucleate guanine 1-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.187"^^xsd:string) "S-adenosyl-L-methionine:rRNA (guanine-1-N-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.187"^^xsd:string) "rRNA(m(1)G)methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.187"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + guanine(745) in 23S rRNA = N(1)-methylguanine(745) in 23S rRNA + S-adenosyl-L-homocysteine."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.187"^^xsd:string) "ribosomal RNA(m(1)G)-methylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.187"^^xsd:string) "rlmA(I) methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.188"^^xsd:string) "23S rRNA m(1)G(748) methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "23S rRNA (guanine(748)-N(1))-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.188"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + guanine(748) in 23S rRNA = N(1)-methylguanine(748) in 23S rRNA + S-adenosyl-L-homocysteine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "16S rRNA (guanine(966)-N(2))-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.171"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(966) in 16S rRNA = N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "16S rRNA (guanine(1207)-N(2))-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.172"^^xsd:string) "M(2)G1207 methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.172"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1207) in 16S rRNA = N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "23S rRNA (guanine(2445)-N(2))-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.173"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(2445) in 23S rRNA = N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.174"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = N(2)-methylguanosine(1835) in 23S rRNA + S-adenosyl-L-homocysteine."^^xsd:string) AnnotationAssertion(rdfs:label "23S rRNA (guanine(1835)-N(2))-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.260"^^xsd:string) "dolichyl-P-mannose:Man(7)GlcNAc(2)-PP-dolichyl mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.260"^^xsd:string) "dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl alpha-6-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.260"^^xsd:string) Annotation( "RHEA:29538"^^xsd:string) "Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.261"^^xsd:string) Annotation( "RHEA:29542"^^xsd:string) "Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->6))-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.46"^^xsd:string) "Catalysis of the reaction: an aliphatic (R)-hydroxynitrile = an aliphatic aldehyde or ketone + hydrogen cyanide."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.46"^^xsd:string) "(R)-HNL activity"^^xsd:string) AnnotationAssertion(rdfs:label "aliphatic (R)-hydroxynitrile lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.46"^^xsd:string) "(R)-hydroxynitrile lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.2.46"^^xsd:string) "(R)-oxynitrilase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.1.2.46"^^xsd:string) "Catalysis of the reaction: (2R)-2-hydroxy-2-methylbutanenitrile = butan-2-one + hydrogen cyanide."^^xsd:string) AnnotationAssertion(rdfs:label "(2R)-2-hydroxy-2-methylbutanenitrile lyase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "acetone-cyanohydrin acetone-lyase (cyanide-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R01553"^^xsd:string) Annotation( "MetaCyc:ACETONE-CYANHYDRIN-LYASE-RXN"^^xsd:string) "Catalysis of the reaction: acetone cyanohydrin = hydrogen cyanide + acetone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.82"^^xsd:string) "(all-E) hexaprenyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.82"^^xsd:string) "hexaprenyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.82"^^xsd:string) "hexaprenyl pyrophosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:27558"^^xsd:string) "Catalysis of the reaction: geranylgeranyl diphosphate + 2 isopentenyl diphosphate = 2 diphosphate + all-trans-hexaprenyl diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.82"^^xsd:string) "(all-trans)-hexaprenyl-diphosphate synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.84"^^xsd:string) "nonaprenyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.84"^^xsd:string) Annotation( "RHEA:27566"^^xsd:string) "Catalysis of the reaction: geranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-nonaprenyl diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.84"^^xsd:string) "solanesyl diphosphate synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.84"^^xsd:string) "solPP synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.84"^^xsd:string) "solanesyl-diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.84"^^xsd:string) "SPP-synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.84"^^xsd:string) "SPP synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.5.1.85"^^xsd:string) "nonaprenyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.85"^^xsd:string) "solanesyl diphosphate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.85"^^xsd:string) "solanesyl diphosphate synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.85"^^xsd:string) "Catalysis of the reaction: geranylgeranyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-nonaprenyl diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.258"^^xsd:string) "man(5)GlcNAc(2)-PP-Dol mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.258"^^xsd:string) "dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "RHEA:29530"^^xsd:string) "Catalysis of the reaction: an alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.259"^^xsd:string) "dolichylphosphomannose-dependent ALG9 mannosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.259"^^xsd:string) Annotation( "RHEA:29534"^^xsd:string) "Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CTP:tRNA cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R09383"^^xsd:string) "Catalysis of the reaction: a tRNA precursor + CTP = a tRNA with a 3' cytidine end + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CTP:3'-cytidine-tRNA cytidylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R09384"^^xsd:string) "Catalysis of the reaction: a tRNA with a 3' cytidine + CTP = a tRNA with a 3' CC end + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ATP:3'-CC-tRNA adenylyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R09386"^^xsd:string) "Catalysis of the reaction: a tRNA with a 3' CC end + ATP = a tRNA with a 3' CCA end + diphosphate."^^xsd:string) AnnotationAssertion( "ATP:tRNA adenylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.2.7"^^xsd:string) "methanol dehydrogenase (cytochrome c) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.7"^^xsd:string) "methanol dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methanol ferricytochrome-c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R01146"^^xsd:string) "Catalysis of the reaction: methanol + 2 ferricytochrome c = formaldehyde + 2 ferrocytochrome c + 2 H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.2.7"^^xsd:string) "ethanol dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ethanol cytochrome-c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R09127"^^xsd:string) "Catalysis of the reaction: ethanol + 2 cytochrome c(L) = acetaldehyde + 2 reduced cytochrome c(L) + 2 H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.7"^^xsd:string) "ethanol dehydrogenase (cytochrome c) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-chloroethanol cytochrome-c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.7"^^xsd:string) "2-chloroethanol dehydrogenase (cytochrome c) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.7"^^xsd:string) "2-chloroethanol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R09128"^^xsd:string) "Catalysis of the reaction: 2-chloroethanol + 2 cytochrome c(L) = chloroacetaldehyde + 2 reduced cytochrome c(L)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alcohol dehydrogenase (cytochrome c(L)) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.7"^^xsd:string) Annotation( ) "alcohol:cytochrome c(L) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.7"^^xsd:string) "Catalysis of the reaction: primary alcohol + 2 cytochrome c(L) = 2 reduced cytochrome c(L) + an aldehyde + 2 H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.2.8"^^xsd:string) "quinoprotein alcohol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.8"^^xsd:string) "Catalysis of the reaction: primary alcohol + 2 cytochrome c = 2 reduced cytochrome c + an aldehyde + 2 H+."^^xsd:string) AnnotationAssertion(rdfs:label "alcohol dehydrogenase (cytochrome c) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.8"^^xsd:string) Annotation( ) "alcohol:cytochrome c oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "KEGG:R05198"^^xsd:string) "Catalysis of the reaction: ethanol + 2 cytochrome c = 2 reduced cytochrome c + acetaldehyde."^^xsd:string) AnnotationAssertion(rdfs:label "ethanol:cytochrome c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.8"^^xsd:string) "ethanol dehydrogenase (cytochrome c) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "KEGG:R05285"^^xsd:string) "Catalysis of the reaction: 2-chloroethanol + 2 cytochrome c = chloroacetaldehyde + 2 reduced cytochrome c."^^xsd:string) AnnotationAssertion(rdfs:label "2-chloroethanol:cytochrome c oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.2.8"^^xsd:string) "2-chloroethanol dehydrogenase (cytochrome c) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.163"^^xsd:string) "cyclopentanol:NADP+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.163"^^xsd:string) "cyclopentanol:NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cyclopentanol dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.163"^^xsd:string) Annotation( "RHEA:11731"^^xsd:string) "Catalysis of the reaction: cyclopentanol + NAD(+) = cyclopentanone + H(+) + NADH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5-valerolactone hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the reaction: 5-valerolactone + H2O = 5-hydroxyvalerate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) Annotation( "GOC:mlg"^^xsd:string) "Catalysis of the reaction: 5-oxovalerate + NADP+ + H2O = glutarate + NADPH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "5-oxovalerate dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mannose:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ct"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: mannose + H+ = mannose + H+."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fructose:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ct"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose + H+ = fructose + H+."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ct"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose + H+ = D-glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. D-glucose is the dextrorotatory D-enantiomer of glucose."^^xsd:string) AnnotationAssertion(rdfs:label "D-glucose:hydrogen symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jid"^^xsd:string) Annotation( "GOC:jsg"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "D-glucose transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "connexon channel activity"^^xsd:string) AnnotationAssertion(rdfs:label "gap junction hemi-channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dgh"^^xsd:string) "A wide pore channel activity that enables the transport of a solute across a membrane via a gap junction hemi-channel. Two gap junction hemi-channels coupled together form a complete gap junction."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "adiponectin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) Annotation( "PMID:15210937"^^xsd:string) "Interacting selectively and non-covalently with adiponectin, a protein hormone produced by adipose tissue that modulates a number of metabolic processes, including glucose regulation and fatty acid catabolism."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lipase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Stops, prevents or reduces the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Modulates the activity of a ligase."^^xsd:string) AnnotationAssertion(rdfs:label "ligase regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "ligase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Stops, prevents or reduces the activity of a ligase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "ubiquitin-protein ligase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Stops, prevents or reduces the activity of a ubiquitin-protein ligase."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "ubiquitin-protein ligase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Modulates the activity of a ubiquitin-protein ligase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "C3HC4-type RING finger domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:amm"^^xsd:string) Annotation( "InterPro:IPR001841"^^xsd:string) Annotation( "InterPro:IPR018957"^^xsd:string) "Interacting selectively and non-covalently with a C3HC4-type zinc finger domain of a protein. The C3HC4-type zinc finger is a variant of RING finger, is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C, where X is any amino acid. Many proteins containing a C3HC4-type RING finger play a key role in the ubiquitination pathway."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "PMID:10519557"^^xsd:string) "Catalysis of movement along a microfilament towards the minus end, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP). The minus end of an actin filament is the end that does not preferentially add actin monomers."^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "pointed-end directed actin-filament motor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "minus-end directed actin filament motor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "minus-end directed actin-filament motor activity"^^xsd:string) AnnotationAssertion(rdfs:label "minus-end directed microfilament motor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "PMID:10519557"^^xsd:string) "Catalysis of movement along a microfilament towards the plus end, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP). The plus end of an actin filament is the end that preferentially adds actin monomers."^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "barbed-end directed actin-filament motor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "plus-end directed actin-filament motor activity"^^xsd:string) AnnotationAssertion(rdfs:label "plus-end directed microfilament motor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "plus-end directed actin filament motor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "BK channel activity"^^xsd:string) AnnotationAssertion(rdfs:label "large conductance calcium-activated potassium channel activity"^^xsd:string) AnnotationAssertion( "BK KCa channels"^^xsd:string) AnnotationAssertion( "BK calcium-activated potassium channel activity"^^xsd:string) AnnotationAssertion( "large conductance KCa channels"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "ISBN:0815340729"^^xsd:string) Annotation( "PMID:17115074"^^xsd:string) "Catalysis of the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:seeAlso "receptor activity") AnnotationAssertion(Annotation( "GOC:mtg_MIT_16mar07"^^xsd:string) "The molecular function that accepts an input of one form and creates an output of a different form."^^xsd:string) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "molecular transducer"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "binding, bridging"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_MIT_16mar07"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way."^^xsd:string) AnnotationAssertion( "molecular adaptor activity"^^xsd:string) AnnotationAssertion( "LEGO") SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "BDNF receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "brain-derived neurotrophic factor receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "BDNF-activated receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) "Combining with a brain-derived neurotrophic factor and transmitting the signal across the plasma membrane to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "brain-derived neurotrophic factor-activated receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "Combining with the peptide apelin to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "apelin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "LCAT activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) Annotation( "PMID:4335615"^^xsd:string) "Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylcholine-sterol O-acyltransferase activator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "lipase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Increases the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "lipoprotein lipase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) Annotation( "PMID:10727238"^^xsd:string) "Increases the activity of a lipoprotein lipase, an enzyme that catalyzes of the hydrolysis of a lipid within a lipoprotein."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "Stops, prevents or reduces the activity of a lysozyme, an enzyme that hydrolyses the beta- (1,4) glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan."^^xsd:string) AnnotationAssertion(rdfs:label "lysozyme inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Modulates the activity of GTP cyclohydrolase I. GTP cyclohydrolase I activity catalyzes the reaction: GTP + 2 H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "GTP cyclohydrolase I regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "peptidyl-dipeptidase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Stops, prevents or reduces the activity of a peptidyl-dipeptidase. Peptidyl-dipeptidase activity catalyzes the release of C-terminal dipeptides from a polypeptide chain."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "NTPase regulator activity"^^xsd:string) AnnotationAssertion(rdfs:label "nucleoside-triphosphatase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Modulates the rate of NTP hydrolysis by a NTPase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "ATPase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Modulates the rate of ATP hydrolysis by an ATPase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Stops, prevents or reduces the activity of an endoribonuclease, any enzyme that catalyzes the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks."^^xsd:string) AnnotationAssertion(rdfs:label "endoribonuclease inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "DNase inhibitor activity"^^xsd:string) AnnotationAssertion(rdfs:label "deoxyribonuclease inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Stops, prevents or reduces the activity of deoxyribonuclease."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "coreceptor activity involved in epidermal growth factor receptor signaling pathway"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "coreceptor activity involved in epidermal growth factor receptor signalling pathway"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Combining with an extracellular messenger, and in cooperation with a primary EGF receptor, initiating a change in cell activity through the EGF receptor signaling pathway."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phospholipase D inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Stops, prevents or reduces the activity of a phospholipase D, an enzyme that catalyzes the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Increases the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides."^^xsd:string) AnnotationAssertion(rdfs:label "endopeptidase activator activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds."^^xsd:string) AnnotationAssertion(rdfs:label "peptidase regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides."^^xsd:string) AnnotationAssertion(rdfs:label "endopeptidase regulator activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "L-arginine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "Catalysis of the stereospecific transfer of L-arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "O-acetyl-ADP-ribose deacetylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "Catalysis of the reaction O-acetyl-ADP-ribose + H2O = ADP-ribose + acetate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "murein tripeptide carboxypeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "PMID:22970852"^^xsd:string) "Catalysis of the reaction L-Ala-gamma;-D-Glu-meso-Dap (murein tripeptide) + H2O = L-Ala-γ-D-Glu + meso-diaminopimelate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sulfinylpropanyl adenylate synthase"^^xsd:string) AnnotationAssertion(Annotation( "PMID:8346915"^^xsd:string) "SPA synthase"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "PMID:8346915"^^xsd:string) "Catalysis of the reaction: cysteine sulfanate + GTP + IMP = sulfinylpropanyl adenylate + GDP + 3 H(+) + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "high affinity fructose transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "PMID:10735857"^^xsd:string) "Catalysis of the transfer of fructose from one side of a membrane to the other. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclic-GMP-AMP synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "PMID:23258413"^^xsd:string) "Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic GMP-AMP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "PMID:23242255"^^xsd:string) "Catalysis of the ATP-dependent dehydration of t6A to form cyclic t6A."^^xsd:string) AnnotationAssertion(rdfs:label "tRNA threonylcarbamoyladenosine dehydratase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA topoisomerase II activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; changes the linking number in multiples of 2."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is not coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2."^^xsd:string) AnnotationAssertion(rdfs:label "DNA topoisomerase type II (ATP-independent) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclic-GMP-AMP binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "PMID:23258412"^^xsd:string) "Interacting selectively and non-covalently with cyclic-GMP-AMP (cGAMP) cyclic nucleotide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucose 6-phosphate:inorganic phosphate antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "PMID:18337460"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + inorganic phosphate(in) = glucose 6-phosphate(in) + inorganic phosphate(out)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "Catalysis of the reaction 1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-naphthoate + CoA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3-demethylubiquinone-n 3-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.64"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-n = S-adenosyl-L-homocysteine + ubiquinone-n."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-6 = S-adenosyl-L-homocysteine + ubiquinone-6."^^xsd:string) AnnotationAssertion(rdfs:label "3-demethylubiquinone-6 3-O-methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "PMID:21356517"^^xsd:string) "Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UMP + (1,4)-alpha-D-glucosyl(n)-glucose-1-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "glycogen synthase activity, transferring glucose-1-phosphate"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclin-dependent protein serine/threonine kinase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "PMID:2569363"^^xsd:string) Annotation( "PMID:3322810"^^xsd:string) "Increases the activity of a cyclin-dependent protein serine/threonine kinase."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "Lys63-specific deubiquitinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:pg"^^xsd:string) Annotation( "PMID:18313383"^^xsd:string) "Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-acyl homoserine lactone synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "autoinducer-1 synthase"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "Catalyzing the reaction: acyl-[acyl-carrier-protein] + S-adenosyl-L-methionine -> [acyl-carrier- protein] + S-methyl-5'-thioadenosine + N-acyl-L-homoserine lactone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile."^^xsd:string) AnnotationAssertion(rdfs:label "aspartic-type peptidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutamic-type peptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "threonine-type peptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) "Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cysteine-type exopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#EXOPEPTIDASE"^^xsd:string) "Catalysis of the hydrolysis of C- or N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cysteine-type aminopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#AMINOPEPTIDASE"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) "Catalysis of the hydrolysis of N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#AMINOPEPTIDASE"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) "Catalysis of the hydrolysis of N-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions."^^xsd:string) AnnotationAssertion(rdfs:label "metalloaminopeptidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glutamic-type endopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#ENDOPEPTIDASE"^^xsd:string) "Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0716720094"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#EXOPEPTIDASE"^^xsd:string) "Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)."^^xsd:string) AnnotationAssertion(rdfs:label "serine-type exopeptidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0716720094"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#AMINOPEPTIDASE"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) "Catalysis of the hydrolysis of a peptide bond not more than three residues from the N-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)."^^xsd:string) AnnotationAssertion(rdfs:label "serine-type aminopeptidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of peptide bonds formed between D-amino acids."^^xsd:string) AnnotationAssertion(rdfs:label "peptidase activity, acting on D-amino acid peptides"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of peptide bonds formed between L-amino acids."^^xsd:string) AnnotationAssertion(rdfs:label "peptidase activity, acting on L-amino acid peptides"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Catalysis of the hydrolysis of a peptide bond in an oligopeptide, i.e. a molecule containing a small number (2 to 20) of amino acid residues connected by peptide bonds."^^xsd:string) AnnotationAssertion(rdfs:label "oligopeptidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "armadillo repeat binding"^^xsd:string) AnnotationAssertion( "armadillo domain binding"^^xsd:string) AnnotationAssertion(rdfs:label "armadillo repeat domain binding"^^xsd:string) AnnotationAssertion( "Arm repeat domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) Annotation( "InterPro:IPR000225"^^xsd:string) "Interacting selectively and non-covalently with the armadillo repeat domain of a protein, an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity protein armadillo. Arm-repeat proteins are involved in various processes, including intracellular signalling and cytoskeletal regulation."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carbon monoxide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) "Interacting selectively and non-covalently with carbon monoxide (CO)."^^xsd:string) AnnotationAssertion( "CO binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) "Interacting selectively and non-covalently with nitric oxide (NO)."^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:16480"^^xsd:string) "nitrosyl binding"^^xsd:string) AnnotationAssertion( "NO binding"^^xsd:string) AnnotationAssertion( "nitrogen monoxide binding"^^xsd:string) AnnotationAssertion(rdfs:label "nitric oxide binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) "Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of carbon monoxide (CO)."^^xsd:string) AnnotationAssertion(rdfs:label "carbon monoxide sensor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "telomeric RNA repeat binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "PMID:16884717"^^xsd:string) "Interacting selectively and non-covalently with the telomerase RNA template or to RNA complementary to it."^^xsd:string) AnnotationAssertion(rdfs:label "telomeric RNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: purine NTP + H2O = purine NDP + phosphate, to drive the unwinding of a DNA or RNA helix."^^xsd:string) AnnotationAssertion(rdfs:label "purine NTP-dependent helicase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: GTP + H2O = GDP + phosphate, to drive the unwinding of a DNA or RNA helix."^^xsd:string) AnnotationAssertion(rdfs:label "GTP-dependent helicase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "rRNA (pseudouridine) methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "rRNA (pseudouridine-N3-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylguanosine."^^xsd:string) AnnotationAssertion(rdfs:label "rRNA (guanosine-2'-O-)-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "rRNA (adenine-C2-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "PMID:20007606"^^xsd:string) Annotation( "PMID:20184321"^^xsd:string) Annotation( "PMID:21368151"^^xsd:string) Annotation( "PMID:21415317"^^xsd:string) Annotation( "PMID:21527678"^^xsd:string) "Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2503) in 23S rRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + rRNA containing C2-methyladenine(2503) in 23S rRNA."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "rRNA (uridine-C5-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "rRNA (uridine-N3-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methyluridine."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine."^^xsd:string) AnnotationAssertion(rdfs:label "rRNA (guanine-N7-)-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fibrinogen binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a type V collagen."^^xsd:string) AnnotationAssertion(rdfs:label "collagen V binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "Combining with thrombospondin and transmitting the signal to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "thrombospondin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fructose binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:28757"^^xsd:string) Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with an RNA polymerase molecule or complex."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "proline-rich region binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a proline-rich region, i.e. a region that contains a high proportion of proline residues, in a protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "InterPro:IPR015129"^^xsd:string) "Interacting selectively and non-covalently with the titin Z domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34."^^xsd:string) AnnotationAssertion(rdfs:label "titin Z domain binding"^^xsd:string) AnnotationAssertion( "Z repeat domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "chromoshadow domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) Annotation( "InterPro:IPR008251"^^xsd:string) Annotation( "PMID:7667093"^^xsd:string) "Interacting selectively and non-covalently with a chromo shadow domain, a protein domain that is distantly related, and found in association with, the chromo domain."^^xsd:string) AnnotationAssertion(rdfs:label "chromo shadow domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chloride-activated potassium channel activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kmv"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) "Catalysis of the chloride concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with fructose 6-phosphate."^^xsd:string) AnnotationAssertion( "fructose 6-phosphate binding"^^xsd:string) AnnotationAssertion(rdfs:label "fructose-6-phosphate binding"^^xsd:string) AnnotationAssertion( "D-fructose 6-phosphate binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:rph"^^xsd:string) "Interacting selectively and non-covalently with the delta subunit of the catenin complex."^^xsd:string) AnnotationAssertion(rdfs:label "delta-catenin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "CNTF binding"^^xsd:string) AnnotationAssertion(rdfs:label "ciliary neurotrophic factor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the cytokine ciliary neurotrophic factor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://128.240.24.212/cgi-bin/omd?isopeptide+bond"^^xsd:string) "Catalysis of the hydrolysis of an isopeptide bond. An isopeptide bond is an amide linkage between a carboxyl group of one amino acid and an amino group of another amino acid in which at least one of these groups is not on the a-carbon of one of the amino acids (for example, the link between an epsilon-amino group of a lysine molecule to a carboxyl group on a second amino acid is an isopeptide bond)."^^xsd:string) AnnotationAssertion(rdfs:label "isopeptidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "endoglin"^^xsd:string) AnnotationAssertion( "betaglycan"^^xsd:string) AnnotationAssertion(rdfs:label "transforming growth factor beta receptor activity, type III"^^xsd:string) AnnotationAssertion( "transforming growth factor beta ligand binding to type III receptor"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9759503"^^xsd:string) "Combining with transforming growth factor beta to initiate a change in cell activity; facilitates ligand binding to type I and type II TGF-beta receptors."^^xsd:string) AnnotationAssertion( "type III transforming growth factor beta receptor activity"^^xsd:string) AnnotationAssertion( "type III TGFbeta receptor activity"^^xsd:string) AnnotationAssertion( "type III TGF-beta receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "small conjugating protein-specific endopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "small conjugating protein-specific isopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of an isopeptide bond between a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO) and a protein to which the small protein has been conjugated."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within the small conjugating protein SUMO."^^xsd:string) AnnotationAssertion(rdfs:label "SUMO-specific endopeptidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "SUMO-specific isopeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydrolysis of an isopeptide bond between the small conjugating protein SUMO and a protein to which SUMO has been conjugated."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) "25S rRNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) "Interacting selectively and non-covalently with the large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA."^^xsd:string) AnnotationAssertion(rdfs:label "LSU rRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "SSU rRNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) "Interacting selectively and non-covalently with the small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA."^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) "18S rRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA polymerase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a DNA polymerase."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:11445442"^^xsd:string) "The action characteristic of growth hormone, a peptide hormone that is secreted by the anterior pituitary or the placenta into the circulation, and binds to membrane receptors in target tissues to stimulate body growth."^^xsd:string) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "pituitary growth hormone activity"^^xsd:string) AnnotationAssertion(rdfs:label "growth hormone activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11445442"^^xsd:string) "GH activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "placental growth hormone activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mcc"^^xsd:string) Annotation( "PMID:17535911"^^xsd:string) Annotation( "PMID:19049972"^^xsd:string) "Catalysis of the reaction: L-methionine R-oxide + thioredoxin = L-methionine + thioredoxin disulfide; can act on free oxidized methionine with specificity for the R enantiomer; does not act on oxidized methionine in peptide linkage. Thioredoxin disulfide is the oxidized form of thioredoxin."^^xsd:string) AnnotationAssertion(rdfs:label "methionine-R-sulfoxide reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.9"^^xsd:string) "MenD"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.9"^^xsd:string) Annotation( "RHEA:25596"^^xsd:string) "Catalysis of the reaction: 2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO(2)."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.2.1.9"^^xsd:string) "SEPHCHC synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.2.99.20"^^xsd:string) "YfbB"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.20"^^xsd:string) "SHCHC synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.20"^^xsd:string) "6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.20"^^xsd:string) Annotation( "RHEA:25600"^^xsd:string) "Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylate + pyruvate."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.20"^^xsd:string) "MenH"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.99.20"^^xsd:string) "2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:MONOMER-12314"^^xsd:string) "sulfide-quinone reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfide:quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "sulphide:quinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:R17-RXN"^^xsd:string) "Catalysis of the reaction: hydrogen sulfide + a quinone = S0 + a hydroquinone."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-8156"^^xsd:string) "Catalysis of the reaction: hydrogen sulfide + oxidized cytochrome c = S0 + reduced cytochrome c."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "sulphide dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8156"^^xsd:string) "flavocytochrome c sulfide dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfide dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:SULFFEOXIDO-RXN"^^xsd:string) "hydrogen sulfide:ferric ion oxidoreductase"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:SULFFEOXIDO-RXN"^^xsd:string) "Catalysis of the reaction: a perthiol + 4 Fe3+ + 3 H2O = sulfite + a thiol + 4 Fe2+ + 8 H+."^^xsd:string) AnnotationAssertion(rdfs:label "sulfur:ferric ion oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:pde"^^xsd:string) Annotation( "PMID:10198260"^^xsd:string) "Catalysis of the reaction: ATP + pristanate + CoA = AMP + diphosphate + pristanoyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "pristanate-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "pristanoyl-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "pristanate:CoA ligase (AMP-forming)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:16751265"^^xsd:string) "Catalysis of the hydrolysis of phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between a DNA topoisomerase and DNA."^^xsd:string) AnnotationAssertion(rdfs:label "tyrosyl-DNA phosphodiesterase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5'-tyrosyl-DNA phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16751265"^^xsd:string) "Catalysis of the hydrolysis of 5'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidylinositol-4-phosphate binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "vitamin B6 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:17310"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde, a form of vitamin B6."^^xsd:string) AnnotationAssertion(rdfs:label "pyridoxal binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:16410"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6."^^xsd:string) AnnotationAssertion(rdfs:label "pyridoxamine binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:16709"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with pyridoxine, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6."^^xsd:string) AnnotationAssertion(rdfs:label "pyridoxine binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "radical SAM enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:17291766"^^xsd:string) Annotation( "PMID:18307109"^^xsd:string) "Catalysis of a reaction in which S-adenosyl-L-methionine (SAM) undergoes reductive cleavage to serve as a source of the 5'-deoxyadenosyl radical."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:18953358"^^xsd:string) "HMP-P synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18953358"^^xsd:string) "ThiC"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18953358"^^xsd:string) "Catalysis of the reaction: 5-aminoimidazole ribonucleotide + S-adenosylmethionine = 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate + 5'deoxyadenosine."^^xsd:string) AnnotationAssertion(rdfs:label "4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:17459943"^^xsd:string) Annotation( "PMID:19154717"^^xsd:string) "Combining with ferritin, and delivering ferritin into the cell via endocytosis."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "ferritin complex receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "ferritin receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NAPE-specific phospholipase D activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:elh"^^xsd:string) Annotation( "PMID:14634025"^^xsd:string) Annotation( "PMID:15878693"^^xsd:string) "Catalysis of the release of N-acylethanolamine from N-acyl-phosphatidylethanolamine (NAPE) to generate N-acylethanolamine (NAE)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jp"^^xsd:string) "phosphatidate binding"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:16337"^^xsd:string) Annotation( "GOC:jp"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Interacting selectively and non-covalently with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Stops, prevents, or reduces the activity of an inwardly rectifying potassium channel."^^xsd:string) AnnotationAssertion(rdfs:label "inward rectifier potassium channel inhibitor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:rph"^^xsd:string) "Interacting selectively and non-covalently with thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland."^^xsd:string) AnnotationAssertion(rdfs:label "thyroid hormone binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "triiodothyronine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "thyroxine binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Interacting selectively and non-covalently with a lipoprotein particle receptor."^^xsd:string) AnnotationAssertion(rdfs:label "lipoprotein particle receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) "very-low-density lipoprotein receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "VLDL receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a very-low-density lipoprotein receptor."^^xsd:string) AnnotationAssertion(rdfs:label "very-low-density lipoprotein particle receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "VLDLR binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "apolipoprotein E receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aromatase activity"^^xsd:string) AnnotationAssertion( "estrogen synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:cb"^^xsd:string) "Catalysis of the reduction of an aliphatic ring to yield an aromatic ring."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aspartate binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:29995"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with aspartate, the alpha-amino-acid anion of 2-aminobutanedioic acid that has formula C4H5NO4."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "aspartic acid binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "flap-structured DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:15189154"^^xsd:string) "Interacting selectively and non-covalently with a flap structure in DNA. A DNA flap structure is one in which a single-stranded length of DNA or RNA protrudes from a double-stranded DNA molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:15189154"^^xsd:string) "Interacting selectively and non-covalently with a 3'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 3'-end of DNA or RNA protrudes from a double-stranded DNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "3'-flap-structured DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5'-flap-structured DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:15189154"^^xsd:string) "Interacting selectively and non-covalently with a 5'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 5'-end of DNA or RNA protrudes from a double-stranded DNA molecule. 5'-flap structures can be formed during DNA repair or lagging strand synthesis; in the latter case RNA flaps form from lagging strand RNA primers."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:9485316"^^xsd:string) "LSPas binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9485316"^^xsd:string) "LSP non-coding strand binding"^^xsd:string) AnnotationAssertion(rdfs:label "mitochondrial light strand promoter anti-sense binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9485316"^^xsd:string) "Interacting selectively and non-covalently with the anti-sense strand of the light strand promoter, a promoter located on the light, or cytosine-rich, strand of mitochondrial DNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mitochondrial heavy strand promoter anti-sense binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9485316"^^xsd:string) "HSPas binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9485316"^^xsd:string) "HSP non-coding strand binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9485316"^^xsd:string) "Interacting selectively and non-covalently with the anti-sense strand of the heavy strand promoter, a promoter located on the heavy, or guanine-rich, strand of mitochondrial DNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:9485316"^^xsd:string) "LSP coding strand binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:9485316"^^xsd:string) "LSPs binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9485316"^^xsd:string) "Interacting selectively and non-covalently with the sense strand of the light strand promoter, a promoter located on the light, or cytosine-rich, strand of mitochondrial DNA."^^xsd:string) AnnotationAssertion(rdfs:label "mitochondrial light strand promoter sense binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:9485316"^^xsd:string) "HSP coding strand binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9485316"^^xsd:string) "Interacting selectively and non-covalently with the sense strand of the heavy strand promoter, a promoter located on the heavy, or guanine-rich, strand of mitochondrial DNA."^^xsd:string) AnnotationAssertion(Annotation( "PMID:9485316"^^xsd:string) "HSPs binding"^^xsd:string) AnnotationAssertion(rdfs:label "mitochondrial heavy strand promoter sense binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) "HMGB1 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "PMID:18431461"^^xsd:string) "Interacting selectively and non-covalently with high mobility group box 1 (HMBGB1)."^^xsd:string) AnnotationAssertion(rdfs:label "high mobility group box 1 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) "HMGB1 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) Annotation( "PMID:18431461"^^xsd:string) "Combining with high mobility group box 1 (HMBGB1) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "high mobility group box 1 receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "NADP binding"^^xsd:string) AnnotationAssertion(rdfs:label "NADP+ binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "oxidized NADP binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "NADP (oxidized) binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "oxidized nicotinamide adenine dinucleotide phosphate binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "reduced NADP binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "reduced nicotinamide adenine dinucleotide phosphate binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "NADP (reduced) binding"^^xsd:string) AnnotationAssertion(rdfs:label "NADPH binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "NAD (oxidized) binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "oxidized NAD binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "NAD binding"^^xsd:string) AnnotationAssertion(rdfs:label "NAD+ binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "oxidized nicotinamide adenine dinucleotide binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "reduced nicotinamide adenine dinucleotide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "NAD (reduced) binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "reduced NAD binding"^^xsd:string) AnnotationAssertion(rdfs:label "NADH binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the reduced form, NADH, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ammonium ion binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:28938"^^xsd:string) Annotation( "GOC:ecd"^^xsd:string) "Interacting selectively and non-covalently with ammonium ions (NH4+)."^^xsd:string) AnnotationAssertion( "ammonium binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:28300"^^xsd:string) Annotation( "GOC:ecd"^^xsd:string) "Interacting selectively and non-covalently with glutamine, 2,5-diamino-5-oxopentanoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "glutamine binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "co-SMAD binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) Annotation( "PMID:19114992"^^xsd:string) "Interacting selectively and non-covalently with a common mediator SMAD signaling protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) Annotation( "PMID:19114992"^^xsd:string) "Interacting selectively and non-covalently with an inhibitory SMAD signaling protein."^^xsd:string) AnnotationAssertion(rdfs:label "I-SMAD binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "R-SMAD binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) Annotation( "PMID:19114992"^^xsd:string) "Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-8452"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + laricitrin = S-adenosyl-L-homocysteine + syringetin."^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.149"^^xsd:string) "CrCOMT2"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.149"^^xsd:string) "flavonoid 3',5'-O-dimethyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "laricitrin 5'-O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.149"^^xsd:string) "S-adenosyl-L-methionine:myricetin O-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "galactose-1-phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: galactose-1-phosphate + H2O = galactose + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:9462881"^^xsd:string) "Catalysis of the reaction: D-galactose-1-phosphate + H2O = D-galactose + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "D-galactose-1-phosphate phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "tubulin-activated ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tubulin-dependent ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:16906148"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of a tubulin dimer to accelerate release of ADP and phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "repressing transcription factor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:txnOH"^^xsd:string) "Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oligosaccharide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with any oligosaccharide, a molecule with between two and (about) 20 monosaccharide residues connected by glycosidic linkages."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "MetaCyc:RXN0-5507"^^xsd:string) Annotation( "PMID:19231875"^^xsd:string) "Catalysis of the reaction: 7,8-dihydroneopterin triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H+."^^xsd:string) AnnotationAssertion(rdfs:label "6-carboxy-5,6,7,8-tetrahydropterin synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "HDL receptor"^^xsd:string) AnnotationAssertion(rdfs:label "high-density lipoprotein particle receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "high-density lipoprotein receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) Annotation( "PMID:9211901"^^xsd:string) "Combining with a high-density lipoprotein particle and delivering the high-density lipoprotein into the cell via endocytosis."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "death domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) Annotation( "InterPro:IPR000488"^^xsd:string) Annotation( "Pfam:PF00531"^^xsd:string) "Interacting selectively and non-covalently with a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:15761036"^^xsd:string) "Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "11-beta-hydroxysteroid dehydrogenase (NAD+) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.146"^^xsd:string) "corticosteroid 11-beta-dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.146"^^xsd:string) "11beta-hydroxysteroid:NADP+ 11-oxidoreductase"^^xsd:string) AnnotationAssertion(rdfs:label "11-beta-hydroxysteroid dehydrogenase (NADP+) activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.146"^^xsd:string) "Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.1.1.146"^^xsd:string) "beta-hydroxysteroid dehydrogenase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of an amino group from L-tryptophan to an acceptor, usually a 2-oxo acid."^^xsd:string) AnnotationAssertion(rdfs:label "L-tryptophan aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:15556404"^^xsd:string) Annotation( "PMID:17525341"^^xsd:string) "Interacting selectively and non-covalently and non-covalently with a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers."^^xsd:string) AnnotationAssertion(rdfs:label "K63-linked polyubiquitin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oleic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:16196"^^xsd:string) Annotation( "GOC:lp"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with oleic acid, the 18-carbon monounsaturated fatty acid (9Z)-octadec-9-enoic acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:17351"^^xsd:string) Annotation( "GOC:lp"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with linoleic acid, the 18-carbon unsaturated fatty acid (9Z,12Z)-octadeca-9,12-dienoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "linoleic acid binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:28842"^^xsd:string) Annotation( "GOC:lp"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with stearic acid, the 18-carbon saturated fatty acid octadecanoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "stearic acid binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of an amino group from L-phenylalanine to an acceptor, usually a 2-oxo acid."^^xsd:string) AnnotationAssertion(rdfs:label "L-phenylalanine aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-tyrosine aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of an amino group from L-tyrosine to an acceptor, usually a 2-oxo acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of an amino group from L-glutamine to an acceptor, usually a 2-oxo acid."^^xsd:string) AnnotationAssertion(rdfs:label "L-glutamine aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "endoribonuclease activity, cleaving siRNA-paired mRNA"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "argonaute endoribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:15105377"^^xsd:string) "Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:15940"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "niacin receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "nicotinic acid receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15940"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12522134"^^xsd:string) "Combining with nicotinic acid to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of an adenylyl group to an acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "adenylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a cytidylyl group to an acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "cytidylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a guanylyl group to an acceptor."^^xsd:string) AnnotationAssertion(rdfs:label "guanylyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "uridylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of an uridylyl group to an acceptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "http://merops.sanger.ac.uk/about/glossary.htm#CATTYPE"^^xsd:string) "Catalysis of the hydrolysis of a dipeptide by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions."^^xsd:string) AnnotationAssertion(rdfs:label "metallodipeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rb"^^xsd:string) "metallo-exo-dipeptidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "metalloexodipeptidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "ergocalciferol 24-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "vitamin D3 24-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "calciferol 24-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "vitamin D 24-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "vitamin D2 24-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "cholecalciferol 24-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:15546903"^^xsd:string) "Catalysis of the hydroxylation of C-24 of any form of vitamin D."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) Annotation( "PMID:17582821"^^xsd:string) "Interacting selectively and non-covalently with an acetylated lysine residue within a histone."^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "acetylated histone residue binding"^^xsd:string) AnnotationAssertion(rdfs:label "histone acetyl-lysine binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19372391"^^xsd:string) "Catalysis of the reaction: methylcytosine + 2-oxoglutarate + O2 = 5-hydroxymethylcytosine + succinate + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "methylcytosine dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:17956872"^^xsd:string) "Interacting selectively and non-covalently with the juvenile hormone response element (JHRE), a conserved sequence found in the promoters of genes whose expression is regulated in response to juvenile hormone."^^xsd:string) AnnotationAssertion(rdfs:label "juvenile hormone response element binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "JHRE binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.1.1.125"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:17898714"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 2) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 2). This reaction is the addition of a methyl group to arginine at position 2 of histone H3."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histone methylase activity (H3-R2 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histone-arginine N-methyltransferase activity (H3-R2 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone methyltransferase activity (H3-R2 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histone methylase activity (H2A-R3 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histone-arginine N-methyltransferase activity (H2A-R3 specific)"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.125"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:17898714"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + (histone H2A)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H2A)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to arginine at position 3 of histone H2A."^^xsd:string) AnnotationAssertion(rdfs:label "histone methyltransferase activity (H2A-R3 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "nucleosome-activated ATPase activity"^^xsd:string) AnnotationAssertion(rdfs:label "nucleosome-dependent ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19165147"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of one or more nucleosomes."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:4.3.2.2"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "adenylosuccinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "adenylosuccinate lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.3.2.2"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "succino AMP-lyase activity"^^xsd:string) AnnotationAssertion(rdfs:label "(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:pde"^^xsd:string) "Catalysis of the reaction: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a proteasome, a large multisubunit protein complex that catalyzes protein degradation."^^xsd:string) AnnotationAssertion(rdfs:label "proteasome binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nicotinamide riboside hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-8441"^^xsd:string) Annotation( "PMID:19001417"^^xsd:string) "Catalysis of the reaction: nicotinamide riboside + H2O = nicotinamide + D-ribose."^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15927"^^xsd:string) "nicotinamide ribonucleoside hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15927"^^xsd:string) "N-ribosylnicotinamide hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "nicotinate ribonucleoside hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:27748"^^xsd:string) "D-ribosylnicotinic acid hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "D-ribosylnicotinate hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19001417"^^xsd:string) "Catalysis of the reaction: nicotinic acid riboside + H2O = nicotinic acid + D-ribose."^^xsd:string) AnnotationAssertion(rdfs:label "nicotinic acid riboside hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "nicotinic acid ribonucleoside hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "nicotinate riboside hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the hydroxylation of C-25 of any form of vitamin D."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "calciferol 25-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "cholecalciferol 25-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "vitamin D 25-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "vitamin D2 25-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "ergocalciferol 25-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "vitamin D response element binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) Annotation( "PMID:17426122"^^xsd:string) "Interacting selectively and non-covalently with the vitamin D response element (VDRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum."^^xsd:string) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) Annotation( "PMID:17426122"^^xsd:string) "VDRE binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a high-density lipoprotein receptor."^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "high-density lipoprotein receptor binding"^^xsd:string) AnnotationAssertion(rdfs:label "high-density lipoprotein particle receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "HDL receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.17.1.4"^^xsd:string) "hypoxanthine oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.4"^^xsd:string) "NAD-hypoxanthine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.4"^^xsd:string) "hypoxanthine/NAD(+) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.4"^^xsd:string) "hypoxanthine/NAD+ oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.4"^^xsd:string) "hypoxanthine-NAD oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:pde"^^xsd:string) "Catalysis of the reaction: hypoxanthine + NAD+ + H2O = xanthine + NADH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "hypoxanthine dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.1.4"^^xsd:string) "hypoxanthine:NAD+ oxidoreductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.17.3.2"^^xsd:string) "hypoxanthine:O(2) oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.2"^^xsd:string) "hypoxanthine:oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hypoxanthine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.2"^^xsd:string) "hypoxanthine-xanthine oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.2"^^xsd:string) "schardinger enzyme"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.2"^^xsd:string) "hypoxanthine:O2 oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:pde"^^xsd:string) "Catalysis of the reaction: hypoxanthine + H2O + O2 = xanthine + H2O2."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.2"^^xsd:string) "xanthine oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.17.3.2"^^xsd:string) "Schardinger enzyme activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "rRNA (cytosine-2'-O-)-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19400805"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylcytosine."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) "unprocessed protein binding"^^xsd:string) AnnotationAssertion(rdfs:label "preprotein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12914940"^^xsd:string) "Interacting selectively and non-covalently with a preprotein, the unprocessed form of a protein destined to undergo co- or post-translational processing."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "inositol 1,4,5 trisphosphate binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "IP3 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with inositol 1,4,5 trisphosphate."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "InsP3 binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "deoxyribonucleoside 5'-monophosphate N-glycosidase activity"^^xsd:string) AnnotationAssertion( "deoxynucleoside 5'-monophosphate N-glycosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ab"^^xsd:string) Annotation( "PMID:17234634"^^xsd:string) "Catalysis of the reaction: a deoxyribonucleoside 5'-monophosphate + H2O = deoxyribose 5-monophosphate + a purine or pyrimidine base."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a receptor that spans a cell membrane and possesses protein serine/threonine kinase activity."^^xsd:string) AnnotationAssertion(rdfs:label "transmembrane receptor protein serine/threonine kinase binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "activin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with an activin receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with a type I activin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type I activin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with a type II activin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "type II activin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "bone morphogenetic protein receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "Interacting selectively and non-covalently with a BMP receptor."^^xsd:string) AnnotationAssertion(rdfs:label "BMP receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sterol desaturase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Catalysis of the introduction of a double bond into a sterol molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with any stretch of purines (adenine or guanine) in an RNA molecule."^^xsd:string) AnnotationAssertion(rdfs:label "poly-purine tract binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:25017"^^xsd:string) Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with 2-amino-4-methylpentanoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "leucine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Leu binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19039103"^^xsd:string) Annotation( "PMID:19362538"^^xsd:string) "Catalysis of the reaction: ATP + protein = diphosphate + adenylyl-protein; mediates the addition of an adenylyl (adenosine 5'-monophosphate; AMP group) to specific residues of target proteins."^^xsd:string) AnnotationAssertion(rdfs:label "protein adenylyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "AMPylator"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "adenosine monophosphate-protein transferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19524510"^^xsd:string) "Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target protein."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "protein glycylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-glycine ligase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19524510"^^xsd:string) "Catalysis of the posttranslational transfer of a glycine residue to the gamma-carboxyl group(s) of one or more specific glutamate residues on a target protein."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "protein glycylase activity, initiating"^^xsd:string) AnnotationAssertion(rdfs:label "protein-glycine ligase activity, initiating"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19524510"^^xsd:string) "Catalysis of the posttranslational transfer of one or more glycine residues to a glycine residue covalently attached to the gamma-carboxyl group of a glutamate residue on a target protein, resulting in the elongation of a polyglycine side chain."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "protein glycylase activity, elongating"^^xsd:string) AnnotationAssertion(rdfs:label "protein-glycine ligase activity, elongating"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tubulin-glycine ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19524510"^^xsd:string) "Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target tubulin molecule; acts on alpha or beta tubulin."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "tubulin glycylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "protein-glutamate ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19524510"^^xsd:string) "Catalysis of the posttranslational transfer of one or more glutamate residues to a specific residue on a target protein."^^xsd:string) AnnotationAssertion(rdfs:label "protein-glutamic acid ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "protein glutamylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "tubulin glutamylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19524510"^^xsd:string) "Catalysis of the posttranslational transfer of one or more glutamate residues to the gamma-carboxyl group(s) of one or more specific glutamate residues on a tubulin molecule."^^xsd:string) AnnotationAssertion(rdfs:label "tubulin-glutamic acid ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "tubulin-glutamate ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "Pfam:PF00096"^^xsd:string) "Interacting selectively and non-covalently with a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion."^^xsd:string) AnnotationAssertion(rdfs:label "C2H2 zinc finger domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) "IL-35 binding"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-35 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) "Interacting selectively and non-covalently with interleukin-35."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "interleukin-35 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) "IL-35 receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) "IL-35R"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:signaling"^^xsd:string) "Combining with interleukin-35 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) "Interacting selectively and non-covalently with the interleukin-35 receptor."^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) "IL-35"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) "interleukin-35 receptor ligand"^^xsd:string) AnnotationAssertion(rdfs:label "interleukin-35 receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19560421"^^xsd:string) "NtQ-amidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protein-N-terminal glutamine amidohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19560421"^^xsd:string) "Catalysis of the reaction: protein-N-terminal-L-glutamine + H2O = protein-N-terminal-L-glutamate + NH3. This reaction is the deamidation of an N-terminal glutamine residue of a protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:pde"^^xsd:string) Annotation( "PMID:11356846"^^xsd:string) "Catalysis of the reaction: a phytoceramide + H2O = a fatty acid + phytosphingosine."^^xsd:string) AnnotationAssertion(rdfs:label "phytoceramidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:pde"^^xsd:string) Annotation( "PMID:12815058"^^xsd:string) "Catalysis of the reaction: dihydrosphingosine 1-phosphate + H2O = dihydrosphingosine + phosphate."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "dihydrosphingosine-1-phosphate phosphohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dihydrosphingosine-1-phosphate phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "sphinganine-1-phosphate phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-2-phosphate(out) = ADP + phosphate + glycerol-2-phosphate(in)."^^xsd:string) AnnotationAssertion(rdfs:label "glycerol-2-phosphate-transporting ATPase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peptidyl-lysine 5-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.4"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "peptidyllysine, 2-oxoglutarate:oxygen 5-oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "peptide-lysine 5-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "protein lysine hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "lysyl hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.11.4"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "peptidyl-lysine, 2-oxoglutarate: oxygen oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19574390"^^xsd:string) "Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "lysine,2-oxoglutarate 5-dioxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "lysine hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "lysine-2-oxoglutarate dioxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.3.3.4"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19583219"^^xsd:string) "Catalysis of the reaction: protoporphyrinogen IX + acceptor = protoporphyrin IX + reduced acceptor."^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.4"^^xsd:string) "protoporphyrinogen IX oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.4"^^xsd:string) "protoporphyrinogen-IX oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.3.3.4"^^xsd:string) "protoporphyrinogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "protoporphyrinogen oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "protoporphyrinogen-IX:menaquinone oxidoreductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19583219"^^xsd:string) "Catalysis of the reaction: protoporphyrinogen IX + menaquinone = protoporphyrin IX + reduced menaquinone."^^xsd:string) AnnotationAssertion(rdfs:label "menaquinone-dependent protoporphyrinogen oxidase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:yaf"^^xsd:string) "Catalysis of the transfer of chromium (Cr) ions from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "chromium ion transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dynein complex binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "growth factor receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with a growth factor receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "myosin VI binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:15473855"^^xsd:string) Annotation( "http://www.mrc-lmb.cam.ac.uk/myosin/Review/Reviewframeset.html"^^xsd:string) "Interacting selectively and non-covalently with a class VI myosin. The myosin VI heavy chain has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain, a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) "Interacting selectively and non-covalently with a heavy chain of a myosin VI complex."^^xsd:string) AnnotationAssertion(rdfs:label "myosin VI heavy chain binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "myosin VI head/neck binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) "Interacting selectively and non-covalently with the head/neck region of a myosin VI heavy chain."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) "Interacting selectively and non-covalently with a light chain of a myosin VI complex."^^xsd:string) AnnotationAssertion(rdfs:label "myosin VI light chain binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sterol-dependent protein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) "Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) in the presence of sterols."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "primary miRNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sl"^^xsd:string) Annotation( "PMID:15531877"^^xsd:string) Annotation( "PMID:15574589"^^xsd:string) "Interacting selectively and non-covalently with a primary microRNA (pri-miRNA) transcript, an RNA molecule that is processed into a short hairpin-shaped structure called a pre-miRNA and finally into a functional miRNA. Both double-stranded and single-stranded regions of a pri-miRNA are required for binding."^^xsd:string) AnnotationAssertion(Annotation( "PMID:15531877"^^xsd:string) Annotation( "PMID:15574589"^^xsd:string) "primary microRNA binding"^^xsd:string) AnnotationAssertion( "pri-miRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:18951094"^^xsd:string) "precursor microRNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pr"^^xsd:string) "pre-microRNA binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18951094"^^xsd:string) "Interacting selectively and non-covalently with a precursor microRNA (pre-miRNA) transcript, a stem-loop-containing precursor of microRNA."^^xsd:string) AnnotationAssertion(rdfs:label "pre-miRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vk"^^xsd:string) "E-box promoter binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) Annotation( "PMID:11812799"^^xsd:string) "Interacting selectively and non-covalently with an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues."^^xsd:string) AnnotationAssertion(rdfs:label "E-box binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sodium-dependent L-ascorbate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:yaf"^^xsd:string) Annotation( "PMID:18094143"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-ascorbate(out) + Na+(out) = L-ascorbate(in) + Na+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "PMID:14665680"^^xsd:string) "Interacting selectively and non-covalently with lipoteichoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "lipoteichoic acid binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "PMID:14665680"^^xsd:string) "Combining with lipoteichoic acid and transmitting the signal to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "lipoteichoic acid receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:17822"^^xsd:string) Annotation( "GOC:rph"^^xsd:string) "Interacting selectively and non-covalently with 2-amino-3-hydroxypropanoic acid."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Ser binding"^^xsd:string) AnnotationAssertion(rdfs:label "serine binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dh"^^xsd:string) "Catalysis of the reaction: aspartate(out) + alanine(in) = aspartate(in) + alanine(out)."^^xsd:string) AnnotationAssertion(rdfs:label "aspartate:alanine antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "aspartate/alanine antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "aspartate-alanine antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histidine:histamine antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dh"^^xsd:string) "Catalysis of the reaction: histidine(out) + histamine(in) = histidine(in) + histamine(out)."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histidine/histamine antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histidine-histamine antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dh"^^xsd:string) "Catalysis of the reaction: tyrosine(out) + tyramine(in) = tyrosine(in) + tyramine(out)."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "tyrosine-tyramine antiporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "tyrosine:tyramine antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "tyrosine/tyramine antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "glutamate/gamma-aminobutyric acid antiporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "glutamate:gamma-aminobutyric acid antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dh"^^xsd:string) "Catalysis of the reaction: tyrosine(out) + tyramine(in) = tyrosine(in) + tyramine(out)."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "glutamate-gamma-aminobutyric acid antiporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dh"^^xsd:string) "glutamate: GABA antiporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:15755723"^^xsd:string) "LPA receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "lysophosphatidic acid receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:52288"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:15755723"^^xsd:string) "Combining with the phospholipid derivative lysophosphatidic acid, and transmitting the signal across the membrane by activating an associated G-protein."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "IPC synthase regulator activity"^^xsd:string) AnnotationAssertion(rdfs:label "inositol phosphoceramide synthase regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Modulates the activity of inositol phosphoceramide synthase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:16848"^^xsd:string) Annotation( "GOC:dh"^^xsd:string) "Interacting selectively and non-covalently with F420, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes."^^xsd:string) AnnotationAssertion(rdfs:label "coenzyme F420 binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pyrroloquinoline quinone binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:18315"^^xsd:string) Annotation( "GOC:dh"^^xsd:string) "Interacting selectively and non-covalently with pyrroloquinoline quinone, PQQ, the coenzyme or the prosthetic group of certain alcohol dehydrogenases and glucose dehydrogenases."^^xsd:string) AnnotationAssertion(Annotation( "GOC:dh"^^xsd:string) "PQQ binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:yaf"^^xsd:string) Annotation( "InterPro:IPR000327"^^xsd:string) "Interacting selectively and non-covalently with a POU domain of a protein. The POU domain is a bipartite DNA binding domain composed of two subunits separated by a non-conserved region of 15-55 amino acids; it is found in several eukaryotic transcription factors."^^xsd:string) AnnotationAssertion(rdfs:label "POU domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "FHA domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "InterPro:IPR000253"^^xsd:string) "Interacting selectively and non-covalently with a FHA domain of a protein. The FHA domain is a phosphopeptide recognition domain found in many regulatory proteins, and consists of approximately 80-100 amino acid residues folded into an 11-stranded beta sandwich."^^xsd:string) AnnotationAssertion(Annotation( "InterPro:IPR000253"^^xsd:string) "Forkhead-associated domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "TIR domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "InterPro:IPR000157"^^xsd:string) "Interacting selectively and non-covalently with a Toll-Interleukin receptor (TIR) domain of a protein. The TIR domain is an intracellular 200 residue domain that is found in the Toll protein, the interleukin-1 receptor (IL-1R), and MyD88; it contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components."^^xsd:string) AnnotationAssertion(Annotation( "InterPro:IPR000157"^^xsd:string) "Toll-Interleukin receptor domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:12575990"^^xsd:string) Annotation( "Pfam:PF00856"^^xsd:string) "Interacting selectively and non-covalently with a SET domain of a protein. SET domains are named after three Drosophila proteins that contain this domain: Su(var), E(z) and trithorax. SET domains are associated with histone lysine methylation."^^xsd:string) AnnotationAssertion(rdfs:label "SET domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) "SET binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "snRNP binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) "Interacting selectively and non-covalently with any part of a small nuclear ribonucleoprotein particle."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "medium-chain-acyl-CoA dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "MCAD activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:59554"^^xsd:string) Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a medium-chain fatty acid residue. A medium chain fatty acid is any fatty acid with a chain length of between C6 and C12."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "type 1 melanocortin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a type 1 melanocortin receptor."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "type 1 melanocortin receptor ligand"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) "Interacting selectively and non-covalently with eukaryotic initiation factor eIF2, a protein complex involved in the initiation of ribosome-mediated translation."^^xsd:string) AnnotationAssertion(rdfs:label "eukaryotic initiation factor eIF2 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:37240"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PubChem_Compound:159296"^^xsd:string) "Catalysis of the transfer of adenosine 3',5'-bisphosphate from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(Annotation( "PubChem_Compound:159296"^^xsd:string) "adenosine 3'-phosphate-5'-phosphate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "PubChem_Compound:159296"^^xsd:string) "adenosine 3',5'-diphosphate transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "adenosine 3',5'-bisphosphate transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclic-guanylate-specific phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.52"^^xsd:string) "cyclic bis(3->5')diguanylate phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.52"^^xsd:string) Annotation( "RHEA:24905"^^xsd:string) "Catalysis of the reaction: cyclic di-3',5'-guanylate + H(2)O = 5'-phosphoguanylyl(3'->5')guanosine + H(+)."^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.52"^^xsd:string) "c-di-GMP phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.52"^^xsd:string) "PDEA1"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.52"^^xsd:string) "VieA"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.52"^^xsd:string) "c-di-GMP-specific phosphodiesterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.4.52"^^xsd:string) "phosphodiesterase A1 activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:6.3.2.29"^^xsd:string) "Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n + L-Asp = ADP + phosphate + [L-Asp(4-L-Arg)]n-L-Asp."^^xsd:string) AnnotationAssertion(rdfs:label "cyanophycin synthetase activity (L-aspartate-adding)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyanophycin synthetase activity (L-arginine-adding)"^^xsd:string) AnnotationAssertion(Annotation( "EC:6.3.2.30"^^xsd:string) "Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n-L-Asp + L-arginine = ADP + phosphate + [L-Asp(4-L-Arg)]n+1."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "snRNA methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "RNA trimethylguanosine synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "PMID:11983179"^^xsd:string) Annotation( "PMID:18775984"^^xsd:string) "Catalysis of two successive methyl transfer reactions from AdoMet to the N-2 atom of guanosine, thereby converting 7-methylguanosine in an RNA cap to 2,2,7 trimethylguanosine."^^xsd:string) AnnotationAssertion(Annotation( "GOC:rl"^^xsd:string) "small nuclear RNA methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11983179"^^xsd:string) "cap hypermethylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "PMID:19897652"^^xsd:string) "Catalysis of the reaction: 7,8-dihydromonapterin + NADPH = tetrahydromonapterin + NADP+."^^xsd:string) AnnotationAssertion(rdfs:label "dihydromonapterin reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19470752"^^xsd:string) "Interacting selectively and non-covalently with a conserved stem-loop structure found in histone pre-mRNAs."^^xsd:string) AnnotationAssertion(rdfs:label "histone pre-mRNA stem-loop binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19470752"^^xsd:string) "Interacting selectively and non-covalently with the downstream cleavage product (DCP) generated by histone pre-mRNA 3'-end processing."^^xsd:string) AnnotationAssertion(rdfs:label "histone pre-mRNA DCP binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:12975319"^^xsd:string) "Interacting selectively and non-covalently with the U7 small nuclear RNA (U7 snRNA)."^^xsd:string) AnnotationAssertion(rdfs:label "U7 snRNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "connexin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19864490"^^xsd:string) "Interacting selectively and non-covalently with a connexin, any of a group of related proteins that assemble to form gap junctions."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "PMID:19965768"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N4-methylcytosine."^^xsd:string) AnnotationAssertion(rdfs:label "rRNA (cytosine-N4-)-methyltransferase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with DNA sequences encoding transfer RNA."^^xsd:string) AnnotationAssertion(rdfs:label "tDNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "autoinducer-2 kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:425228"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "4,5-dihydroxy-pentane-2,3-dione kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "PMID:17274596"^^xsd:string) Annotation( "PMID:20025244"^^xsd:string) "Catalysis of the reaction: 4,5-dihydroxy-pentane-2,3-dione + ATP = 5-phospho-4-hydroxy-pentane-2,3-dione (P-DPD) + ADP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ureidoglycine aminohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:URUR-RXN"^^xsd:string) Annotation( "PMID:19935661"^^xsd:string) Annotation( "PMID:20038185"^^xsd:string) "Catalysis of the reaction: ureidoglycine + H2O = S-ureidoglycolate + NH3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:amm"^^xsd:string) "ANK repeat binding"^^xsd:string) AnnotationAssertion(rdfs:label "ankyrin repeat binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "InterPro:IPR002110"^^xsd:string) "Interacting selectively and non-covalently with an ankyrin repeat of a protein. Ankyrin repeats are tandemly repeated modules of about 33 amino acids; each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90-degree angle, and repeats stack to form an L-shaped structure."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "InterPro:IPR014857"^^xsd:string) "Interacting selectively and non-covalently with a RING-like zinc finger domain domain of a protein. The RING-like domain is a zinc finger domain that is related to the C3HC4 RING finger domain."^^xsd:string) AnnotationAssertion(rdfs:label "RING-like zinc finger domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RIP homotypic interaction motif binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "RHIM binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:11734559"^^xsd:string) "Interacting selectively and non-covalently with a RIP homotypic interaction motif (RHIM) of a protein. The RHIM is a 16-amino-acid motif found in some members, including RIP3, of a family of related kinases."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "pyrimidinergic nucleotide receptor activity, G protein coupled"^^xsd:string) AnnotationAssertion( "G protein coupled pyrimidinergic nucleotide receptor activity"^^xsd:string) AnnotationAssertion( "G-protein-coupled pyrimidinergic nucleotide receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "G-protein coupled pyrimidinergic nucleotide receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "pyrimidinergic nucleotide receptor activity, G-protein coupled"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sl"^^xsd:string) Annotation( "PMID:10736418"^^xsd:string) Annotation( "PMID:12369950"^^xsd:string) Annotation( "PMID:15796906"^^xsd:string) "Combining with a pyrimidine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "histone demethylase activity (H3-K27 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:20622853"^^xsd:string) "Catalysis of the removal of a methyl group from lysine at position 27 of the histone H3 protein."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UFM1 activating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:20018847"^^xsd:string) "Catalysis of the activation of the small ubiquitin-related modifier UFM1, through the formation of an ATP-dependent high-energy thiolester bond."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UFM1 hydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:20018847"^^xsd:string) "Catalysis of the hydrolysis of UFM1, a small ubiquitin-related modifier, from previously modified substrates."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "UFM1 conjugating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:20018847"^^xsd:string) "Catalysis of the covalent attachment of the ubiquitin-like protein UFM1 to other proteins or other substrate molecules."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tetrahydrodictyopterin binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:52447"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with tetrahydrodictyopterin, the pterin 2-amino-6-[(1R,2R)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "D-threo-tetrahydrobiopterin"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "DH4 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "linoleic acid monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "PMID:11042099"^^xsd:string) "Catalysis of an NADPH- and oxygen-dependent reaction that converts linoleic acid to a cis-epoxyoctadecenoic acid."^^xsd:string) AnnotationAssertion(rdfs:label "linoleic acid epoxygenase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:cjk"^^xsd:string) "Catalysis of the transfer of acyl groups from an acyl-CoA to a lysophospholipid."^^xsd:string) AnnotationAssertion(rdfs:label "lysophospholipid acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:cjk"^^xsd:string) "Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidylethanolamine."^^xsd:string) AnnotationAssertion(rdfs:label "lysophosphatidylethanolamine acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dihydroceramidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:10900202"^^xsd:string) "Catalysis of the reaction: a dihydroceramide + H2O = a fatty acid + dihydrosphingosine."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) "RNA/DNA hybrid binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) "Interacting selectively and non-covalently with a RNA/DNA hybrid."^^xsd:string) AnnotationAssertion(rdfs:label "DNA/RNA hybrid binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "PMID:20190044"^^xsd:string) "Catalysis of the reaction: para-aminobenzoyl-glutamate + H2O = para-aminobenzoate + L-glutamate."^^xsd:string) AnnotationAssertion(rdfs:label "para-aminobenzoyl-glutamate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sl"^^xsd:string) "eicosanoid transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sl"^^xsd:string) "Catalysis of the transfer of icosanoids from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "icosanoid transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) "bacterial lipoprotein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "PMID:12077222"^^xsd:string) Annotation( "PMID:12524386"^^xsd:string) Annotation( "PMID:2757794"^^xsd:string) "Interacting selectively and non-covalently with a lipopeptide, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds and containing a nonprotein group consisting of a lipid or lipids."^^xsd:string) AnnotationAssertion(rdfs:label "lipopeptide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) "bacterial lipopeptide binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "biotin-pyruvate-carboxylase ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:10551847"^^xsd:string) "Catalysis of the reaction: ATP + biotin + apo-(pyruvate-carboxylase) = AMP + diphosphate + biotin-(pyruvate-carboxylase)."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "biotin:apo-pyruvate-carboxylase ligase"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "biotin-[pyruvate carboxylase] synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jp"^^xsd:string) "biotin-[pyruvate carboxylase] ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "biotin-pyruvate carboxylase synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "biotin-[pyruvate-carboxylase] ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "aldehyde decarbonylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) Annotation( "PMID:6593720"^^xsd:string) Annotation( "PMID:8718622"^^xsd:string) "Catalysis of the reaction: a C(n) aldehyde = C(n-1) alkane + CO."^^xsd:string) AnnotationAssertion(Annotation( "EC:4.1.99.5"^^xsd:string) Annotation( "GOC:kad"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "decarbonylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:amm"^^xsd:string) "CCL5 binding"^^xsd:string) AnnotationAssertion(rdfs:label "chemokine (C-C motif) ligand 5 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) Annotation( "GOC:amm"^^xsd:string) "Interacting selectively and non-covalently with chemokine (C-C motif) ligand 5."^^xsd:string) AnnotationAssertion(Annotation( "GOC:add"^^xsd:string) "Regulated upon Activation, Normal T-cell Expressed, and Secreted binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "RANTES binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "CAP-Gly domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "InterPro:IPR000938"^^xsd:string) "Interacting selectively and non-covalently with a CAP-Gly domain of a protein. The CAP_Gly domain is a conserved, glycine-rich domain of about 42 residues found in some cytoskeleton-associated proteins, and features a novel protein fold containing three beta-sheets."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:18775313"^^xsd:string) "Interacting selectively and non-covalently and non-covalently with a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers."^^xsd:string) AnnotationAssertion(rdfs:label "K11-linked polyubiquitin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:17525341"^^xsd:string) Annotation( "PMID:20351172"^^xsd:string) "Interacting selectively and non-covalently and non-covalently with a polymer of ubiquitin formed by linkages between lysine residues at position 6 of the ubiquitin monomers."^^xsd:string) AnnotationAssertion(rdfs:label "K6-linked polyubiquitin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "plasma lipoprotein particle binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "plasma lipoprotein binding"^^xsd:string) AnnotationAssertion(rdfs:label "lipoprotein particle binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "lipoprotein binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:6495"^^xsd:string) Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a lipoprotein particle. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a protein-lipid complex, any macromolecular complex that contains both protein and lipid molecules."^^xsd:string) AnnotationAssertion(rdfs:label "protein-lipid complex binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) "IDL binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) "intermediate-density lipoprotein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a intermediate-density lipoprotein particle, a triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm."^^xsd:string) AnnotationAssertion(rdfs:label "intermediate-density lipoprotein particle binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-box binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "N box binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:yaf"^^xsd:string) Annotation( "PMID:11498047"^^xsd:string) "Interacting selectively and non-covalently with an N-box, a DNA motif with the consensus sequence CACNAG that is found in the promoters of genes expressed preferentially at synapses."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "N-box promoter binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:yaf"^^xsd:string) Annotation( "InterPro:IPR009071"^^xsd:string) Annotation( "PMID:18445004"^^xsd:string) "Interacting selectively and non-covalently with an HMG box domain, a protein domain that consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin."^^xsd:string) AnnotationAssertion(rdfs:label "HMG box domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kmv"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a neuropeptide receptor."^^xsd:string) AnnotationAssertion(rdfs:label "neuropeptide receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kmv"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a beta-endorphin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "beta-endorphin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "corazonin receptor binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kmv"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a corazonin receptor."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kmv"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a neuropeptide F receptor."^^xsd:string) AnnotationAssertion(rdfs:label "neuropeptide F receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kmv"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a proctolin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "proctolin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kmv"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a tachykinin receptor."^^xsd:string) AnnotationAssertion(rdfs:label "tachykinin receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein phosphatase type 1 activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) "Increases the activity of the enzyme protein phosphatase type 1."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "vitamin D receptor activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:vk"^^xsd:string) "Interacting (directly or indirectly) with vitamin D receptors such that the proportion of receptors in the active form is increased."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-terminal protein N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:20481588"^^xsd:string) "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser."^^xsd:string) AnnotationAssertion(Annotation( "GOC:rn"^^xsd:string) "X-Pro-Lys N-terminal methyltransferase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:100436"^^xsd:string) Annotation( "GOC:yaf"^^xsd:string) Annotation( "PMID:19057895"^^xsd:string) "Interacting selectively and non-covalently with the amine 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine, a serotonin receptor agonist that can act as a psychedelic drug."^^xsd:string) AnnotationAssertion(Annotation( "PMID:19057895"^^xsd:string) "1-(4-iodo-2,5-dimethoxyphenyl)-2-aminopropane binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:100436"^^xsd:string) "(+/-)2-(4-iodo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine binding"^^xsd:string) AnnotationAssertion(rdfs:label "1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding"^^xsd:string) AnnotationAssertion(Annotation( "PubChem_Compound:1229"^^xsd:string) "4-iodo-2,5-dimethoxyphenylisopropylamine binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "14-3-3 protein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:cna"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "InterPro:IPR000308"^^xsd:string) Annotation( "PMID:15167810"^^xsd:string) Annotation( "PMID:19575580"^^xsd:string) Annotation( "PR:000003237"^^xsd:string) "Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxyl terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:17544"^^xsd:string) "hydrogencarbonate binding"^^xsd:string) AnnotationAssertion(rdfs:label "bicarbonate binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:17544"^^xsd:string) "Interacting selectively and non-covalently with bicarbonate (CHO3-) ions."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:yaf"^^xsd:string) Annotation( "PMID:19460168"^^xsd:string) "Interacting selectively and non-covalently with a CRD (context dependent regulatory) domain, a domain of about 130 residues that is the most divergent region among the LEF/TCF proteins."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "context dependent regulatory domain binding"^^xsd:string) AnnotationAssertion(rdfs:label "CRD domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "citrate secondary active transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:mtg_transport"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Catalysis of the transfer of citrate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "citrate carrier activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dipeptide transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Enables the directed movement of a dipeptide across a membrane into, out of or within a cell, or between cells. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Catalysis of the transfer of a triose phosphate from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "triose-phosphate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Arp2/3 complex binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with an Arp2/3 complex, a protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "coreceptor activity involved in Wnt receptor signaling pathway"^^xsd:string) AnnotationAssertion(Annotation( "GOC:signaling"^^xsd:string) "coreceptor activity involved in Wnt-activated signaling pathway"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "coreceptor activity involved in Wnt receptor signalling pathway"^^xsd:string) AnnotationAssertion(rdfs:label "coreceptor activity involved in Wnt signaling pathway"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "In cooperation with a primary Wnt receptor, initiating a change in cell activity through the Wnt signaling pathway."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "oxidized flavine-adenine dinucleotide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes."^^xsd:string) AnnotationAssertion(rdfs:label "FAD binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "oxidized flavin adenine dinucleotide binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "reduced flavine-adenine dinucleotide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with the reduced form, FADH2, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "reduced flavin adenine dinucleotide binding"^^xsd:string) AnnotationAssertion(rdfs:label "FADH2 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lipopolysaccharide core heptosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-5122"^^xsd:string) "Catalysis of the reaction: glucosyl-heptosyl2-KDO2-lipid A-phosphate + ADP-L-glycero-beta-D-manno-heptose = glucosyl-heptosyl3-KDO2-lipid A-phosphate + ADP + H+."^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:LIPA-CORESYN-PWY"^^xsd:string) "LPS core heptosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lipid A-core heptosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN0-5127"^^xsd:string) "Catalysis of the reaction: galactosyl-glucosyl3-heptosyl3-KDO2-lipid A-bisphosphate + ADP-L-glycero-beta-D-manno-heptose = lipid A-core + ADP + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-11349"^^xsd:string) "Catalysis of the reaction: 2 a peptidoglycan dimer (tetrapeptide) + 3 H2O = a peptidoglycan tetramer with L,D cross-links (L-Lys-D-Asn-L-Lys) + di-trans,poly-cis-undecaprenyl diphosphate + 4 D-alanine."^^xsd:string) AnnotationAssertion(rdfs:label "peptidoglycan L,D-transpeptidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:yaf"^^xsd:string) "beta-transducin repeat domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:yaf"^^xsd:string) "WD domain binding"^^xsd:string) AnnotationAssertion(rdfs:label "WD40-repeat domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:yaf"^^xsd:string) Annotation( "InterPro:IPR017986"^^xsd:string) "Interacting selectively and non-covalently with a WD40 repeat domain of a protein. The WD40 repeat is a short structural motif of approximately 40 amino acids, often terminating in a tryptophan-aspartic acid (W-D) dipeptide. Several of these repeats are combined to form a type of protein domain called the WD domain."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) Annotation( "http://en.wikipedia.org/wiki/Phytochelatin#History"^^xsd:string) "cadystin transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of a phytochelatin into, out of or within a cell, or between cells. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes."^^xsd:string) AnnotationAssertion(rdfs:label "phytochelatin transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) Annotation( "http://en.wikipedia.org/wiki/Phytochelatin#History"^^xsd:string) "cadystin transmembrane transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "phytochelatin transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "ISBN:0198506732"^^xsd:string) "Enables the directed movement of a phytochelatin across a membrane into, out of or within a cell, or between cells. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of glutathione S-conjugate across a membrane."^^xsd:string) AnnotationAssertion(rdfs:label "glutathione S-conjugate-transporting ATPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jl"^^xsd:string) "Catalysis of the hydrolysis of 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans that contributes to the release of ascospores from the ascus."^^xsd:string) AnnotationAssertion(rdfs:label "glucan endo-1,3-beta-D-glucosidase activity involved in ascospore release from ascus"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transmembrane transfer of a chloride ion by a volume-sensitive channel. A volume-sensitive channel is a channel that responds to changes in the volume of a cell."^^xsd:string) AnnotationAssertion(rdfs:label "volume-sensitive chloride channel activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:32878"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n."^^xsd:string) AnnotationAssertion(rdfs:label "alkene binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:25359"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with a modified amino acid."^^xsd:string) AnnotationAssertion(rdfs:label "modified amino acid binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NAADP-sensitive calcium-release channel activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19387438"^^xsd:string) Annotation( "PMID:19557428"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a channel that opens when nicotinic acid adenine dinucleotide phosphate (NAADP) has been bound by the channel complex or one of its constituent parts."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:11752598"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a channel that opens when cyclic adenosine diphosphate ribose (cADPR) has been bound by the channel complex or one of its constituent parts."^^xsd:string) AnnotationAssertion(rdfs:label "cADPR-sensitive calcium-release channel activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:25359"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of modified amino acids from one side of a membrane to the other."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "modified amino acid transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "modified amino acid transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histone threonine kinase activity (H3-T3 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of a phosphate group to the threonine-3 residue of the N-terminal tail of histone H3."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histone-threonine kinase activity (H3-T3 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone kinase activity (H3-T3 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histone serine kinase activity (H2A-S121 specific)"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:19965387"^^xsd:string) "Catalysis of the transfer of a phosphate group to the serine-121 residue of the N-terminal tail of histone H2A."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "histone-serine kinase activity (H2A-S121 specific)"^^xsd:string) AnnotationAssertion(rdfs:label "histone kinase activity (H2A-S121 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "MetaCyc:CPD-7421"^^xsd:string) Annotation( "MetaCyc:CPD1F-118"^^xsd:string) Annotation( "MetaCyc:RXN-5962"^^xsd:string) "Catalysis of the reaction: alpha-carotene + NADPH + O2 + H+ = alpha-cryptoxanthin + NADP+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-carotene epsilon hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) Annotation( "MetaCyc:CPD-7421"^^xsd:string) Annotation( "MetaCyc:CPD1F-118"^^xsd:string) Annotation( "MetaCyc:RXN-5962"^^xsd:string) "Catalysis of the reaction: a carotene + NADPH + O2 + H+ = a beta-ring hydroxylcarotene + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene."^^xsd:string) AnnotationAssertion(rdfs:label "carotene epsilon hydroxylase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Pup ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Pup conjugating enzyme activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sp"^^xsd:string) "Catalysis of ATP-dependent isopeptide bond formation between the carboxy-terminal residue of the small ubiquitin-related modifier Pup and a substrate lysine residue."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of inorganic cations with a valency of two from one side of the membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage."^^xsd:string) AnnotationAssertion(rdfs:label "divalent inorganic cation transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the transfer of inorganic cations with a valency of three from one side of the membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage."^^xsd:string) AnnotationAssertion(rdfs:label "trivalent inorganic cation transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "Rho-dependent protein serine/threonine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) "ROCK kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) Annotation( "PMID:12778124"^^xsd:string) Annotation( "PMID:20230755"^^xsd:string) "Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires binding of the GTPase Rho."^^xsd:string) AnnotationAssertion(Annotation( "GOC:ecd"^^xsd:string) "Rho-associated protein kinase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) Annotation( "PMID:19779199"^^xsd:string) "Catalysis of the meta-hydroxylation of any of the three phenolic rings on triferuloyl spermidine or any of its mono- or di-(hydroxyferuloyl)-spermidine derivatives."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) Annotation( "PMID:19779199"^^xsd:string) "Catalysis of the meta-hydroxylation of any of the three phenolic rings on tricoumaroyl spermidine or any of its mono- or dicaffeoyl spermidine derivatives."^^xsd:string) AnnotationAssertion(rdfs:label "tri-(coumaroyl or caffeoyl) spermidine meta-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:rs"^^xsd:string) "peroxynitritase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rs"^^xsd:string) Annotation( "PMID:11001062"^^xsd:string) "Catalysis of the reaction: 2 R-SH + ONOO- = R-SS-R + NO2- + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "peroxynitrite reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein phosphatase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Increases the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein phosphatase type 2A activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) "Increases the activity of the enzyme protein phosphatase type 2A."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-DOPA binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15765"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Interacting selectively and non-covalently with L-DOPA, the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid."^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:15765"^^xsd:string) "L-dopa binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Tyr binding"^^xsd:string) AnnotationAssertion(rdfs:label "tyrosine binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:18186"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) "Interacting selectively and non-covalently with2-amino-3-(4-hydroxyphenyl)propanoic acid."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) Annotation( "PMID:19779199"^^xsd:string) "Catalysis of the reaction: tricoumaroyl spermidine + NADPH + O2 = dicoumaroyl monocaffeoyl spermidine + NADP+ + H2O."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "tricoumaroyl spermidine meta-hydroxylase activity"^^xsd:string) AnnotationAssertion(rdfs:label "tricoumaroylspermidine meta-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) Annotation( "PMID:19779199"^^xsd:string) "Catalysis of the reaction: dicoumaroyl monocaffeoyl spermidine + NADPH + O2 = monocoumaroyl dicaffeoyl spermidine + NADP+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "dicoumaroyl monocaffeoyl spermidine meta-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) Annotation( "PMID:19779199"^^xsd:string) "Catalysis of the reaction: monocoumaroyl dicaffeoyl spermidine + NADPH + O2 = tricaffeoyl spermidine + NADP+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "monocoumaroyl dicaffeoyl spermidine meta-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) Annotation( "PMID:19779199"^^xsd:string) "Catalysis of the reaction: triferuloyl spermidine + NADPH + O2 = diferuloyl mono-(hydroxyferuloyl) spermidine + NADP+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "triferuloylspermidine meta-hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "triferuloyl spermidine meta-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) Annotation( "PMID:19779199"^^xsd:string) "Catalysis of the reaction: diferuloyl mono-(hydroxyferuloyl) spermidine + NADPH + O2 = monoferuloyl di-(hydroxyferuloyl) spermidine + NADP+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "diferuloyl mono-(hydroxyferuloyl) spermidine meta-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) Annotation( "PMID:19779199"^^xsd:string) "Catalysis of the reaction: monoferuloyl di-(hydroxyferuloyl) spermidine + NADPH + O2 = tri-(hydroxyferuloyl) spermidine + NADP+ + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "monoferuloyl di-(hydroxyferuloyl) spermidine meta-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) "17-beta-ketosteroid reductase (NADPH) activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) "7beta-ketosteroid reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "17-beta-ketosteroid reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) Annotation( "PMID:17074428"^^xsd:string) "Catalysis of the reaction: a 17-beta-ketosteroid + NADPH + H+ = a 17-beta-hydroxysteroid + NADP+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:16864"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:20088964"^^xsd:string) "Interacting selectively and non-covalently with ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment."^^xsd:string) AnnotationAssertion(rdfs:label "ADP-D-ribose binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "ADP-ribose binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "mono-ADP-D-ribose binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:16864"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:20088964"^^xsd:string) "Interacting selectively and non-covalently with monomeric ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment."^^xsd:string) AnnotationAssertion(Annotation( "PMID:20088964"^^xsd:string) "mADPr binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "mono-ADP-ribose binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:61151"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:20088964"^^xsd:string) "Interacting selectively and non-covalently with polymeric ADP-D-ribose, a polymer that is composed of poly-ADP-D-ribose units linked through 1,2-glycosidic bonds at the ribose ring."^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "poly-ADP-ribose binding"^^xsd:string) AnnotationAssertion(rdfs:label "poly-ADP-D-ribose binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:20088964"^^xsd:string) "pADPr binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) Annotation( "PMID:17074428"^^xsd:string) "Catalysis of the reaction: a 17-beta-hydroxysteroid + NADP+ = a 17-oxosteroid + NADPH + H+."^^xsd:string) AnnotationAssertion(rdfs:label "17-beta-hydroxysteroid dehydrogenase (NADP+) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) "xanthosine ribohydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "xanthosine nucleotidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) Annotation( "MetaCyc:RXN0-363"^^xsd:string) Annotation( "PMID:21235647"^^xsd:string) "Catalysis of the reaction: xanthosine + H2O = D-ribose + xanthine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA topoisomerase (ATP-hydrolyzing) regulator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2."^^xsd:string) AnnotationAssertion(rdfs:label "DNA topoisomerase (ATP-hydrolyzing) activator activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:20643647"^^xsd:string) Annotation( "PMID:20657015"^^xsd:string) "Catalysis of the reaction: ATP + N-acetyl-L-aspartate + L-glutamate = ADP + phosphate + N-acetylaspartyl-glutamate."^^xsd:string) AnnotationAssertion(rdfs:label "N-acetyl-L-aspartate-L-glutamate ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:20657015"^^xsd:string) "Catalysis of the reaction: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate."^^xsd:string) AnnotationAssertion(rdfs:label "citrate-L-glutamate ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:2.4.1.-"^^xsd:string) Annotation( "PMID:18385129"^^xsd:string) "Catalysis of the reaction: 4-aminobenzoate + UDP-glucose = p-aminobenzoate-beta-D-glucopyranosyl ester + UDP."^^xsd:string) AnnotationAssertion( "UDP-glucose:pABA acylglucosyltransferase activity"^^xsd:string) AnnotationAssertion( "UDP-glucose:p-aminobenzoate glucosyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "UDP-glucose:4-aminobenzoate acylglucosyltransferase activity"^^xsd:string) AnnotationAssertion( "UDP-glucose:p-aminobenzoate acylglucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:18356490"^^xsd:string) "Catalysis of the reaction: a thalian-diol = a desaturated thalian-diol. This reaction is the introduction of a double bond to a thalian-diol molecule at carbon 15."^^xsd:string) AnnotationAssertion(rdfs:label "thalian-diol desaturase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "S-nitrosoglutathione reductase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10742"^^xsd:string) Annotation( "PMID:11260719"^^xsd:string) "Catalysis of the reaction: glutathione N-hydroxysulfenamide + NADH + H+ = S-nitrosoglutathione + NAD+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "baruol synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-9685"^^xsd:string) Annotation( "PMID:17705488"^^xsd:string) "Catalysis of the reaction: (S)-2,3-epoxysqualene = baruol. Baruol is also known as D:B-Friedo-Baccharan-5,21-dien-3-ol."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-11263"^^xsd:string) "N1,N5,N10-tris-(5-hydroxyferuloyl)spermidine O-methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "trihydroxyferuloyl spermidine O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18557837"^^xsd:string) "Catalysis of the reaction: trihydroxyferuloyl spermidine + S-adenosyl-L-methionine = dihydroxyferuloyl-sinapoyl spermidine + S-adenosyl-L-homocysteine + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(E,E)-geranyllinalool synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10441"^^xsd:string) Annotation( "PMID:18398052"^^xsd:string) "Catalysis of the reaction: all-trans-geranyl-geranyl diphosphate + H2O = (E,E)-geranyllinalool + diphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thalianol hydroxylase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-9631"^^xsd:string) Annotation( "PMID:17474751"^^xsd:string) Annotation( "PMID:18356490"^^xsd:string) "Catalysis of the reaction: a thalianol = a thalian-diol. This reaction is the addition of a hydroxyl group to thalianol ((13R,14R,17E)-podioda-8,17,21-trien-3beta-ol) to create a thalian-diol ((13R,14R,17E)-podioda-8,17,21-trien-3beta,X-diol), where the hydroxyl group may be attached at one of several different available carbons in ring B or C of thalianol, indicated by the X."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-5103"^^xsd:string) Annotation( "PMID:12566586"^^xsd:string) Annotation( "PMID:9747540"^^xsd:string) "Catalysis of the reaction: geranyl diphosphate = sabinene + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "sabinene synthase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-8414"^^xsd:string) Annotation( "PMID:12566586"^^xsd:string) Annotation( "PMID:9442047"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-E-beta-caryophyllene + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "(-)-E-beta-caryophyllene synthase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "alpha-humulene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:12566586"^^xsd:string) Annotation( "PMID:9442047"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = alpha-humulene + diphosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "anthocyanin 5-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15807784"^^xsd:string) "Catalysis of the reaction: an anthocyanin + UDP-D-glucose = an anthocyanin-5-O-glucoside + UDP."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16980563"^^xsd:string) "Catalysis of the reaction: a very long chain fatty acyl-CoA + NADPH + H+ = a very long chain primary alcohol + NADP+ + CoA."^^xsd:string) AnnotationAssertion(rdfs:label "fatty-acyl-CoA reductase (alcohol-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "fatty acyl CoA reductase (alcohol-forming) activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "fatty acyl-CoA reductase (alcohol-forming) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "3R-hydroxyacyl-CoA dehydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16982622"^^xsd:string) "Catalysis of the reaction: 3R-hydroxyacyl-CoA = 2E-enoyl-CoA + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidylinositol-3,5-bisphosphate binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:18397324"^^xsd:string) "Interacting selectively and non-covalently with phosphatidylinositol-3,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 5' positions."^^xsd:string) AnnotationAssertion( "PtdIns(3,5)P2 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methyl indole-3-acetate esterase activity"^^xsd:string) AnnotationAssertion( "indole-3-Acetic acid methyl ester esterase activity"^^xsd:string) AnnotationAssertion( "methyl indole-3-acetate esterase activity"^^xsd:string) AnnotationAssertion( "Methyl IAA esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10711"^^xsd:string) Annotation( "PMID:18467465"^^xsd:string) "Catalysis of the reaction: methyl indole-3-acetate + H2O = indole-3-acetate + methanol + H+."^^xsd:string) AnnotationAssertion( "MeIAA esterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "methyl SA esterase activity"^^xsd:string) AnnotationAssertion( "methylsalicylate esterase activity"^^xsd:string) AnnotationAssertion( "MESA esterase activity"^^xsd:string) AnnotationAssertion(rdfs:label "methyl salicylate esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXNQT-4366"^^xsd:string) Annotation( "PMID:18467465"^^xsd:string) Annotation( "PMID:18643994"^^xsd:string) "Catalysis of the reaction: methyl salicylate + H2O = salicylic acid + methanol + H+."^^xsd:string) AnnotationAssertion( "salicylic acid methyl ester esterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:15233793"^^xsd:string) Annotation( "PMID:18467465"^^xsd:string) "Catalysis of the reaction: a methyl jasmonate + H2O = a jasmonic acid + methanol."^^xsd:string) AnnotationAssertion(rdfs:label "methyl jasmonate esterase activity"^^xsd:string) AnnotationAssertion( "methyl JA esterase activity"^^xsd:string) AnnotationAssertion( "MEJA esterase activity"^^xsd:string) AnnotationAssertion( "jasmonic acid methyl ester esterase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "xyloglucan endotransglucosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.207"^^xsd:string) Annotation( "GOC:ask"^^xsd:string) Annotation( "PMID:1400418"^^xsd:string) Annotation( "PMID:1554366"^^xsd:string) "Catalysis of the hydrolysis of a beta-(1,4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of a xyloglucan or an oligosaccharide of xyloglucan."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Catalysis of the reaction: ADP-ribose + H2O = AMP + ribose-1-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "ADP-ribose pyrophosphohydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ADP-glucose pyrophosphohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Catalysis of the reaction: ADP-glucose + H2O = AMP + glucose-1-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "quercetin 3-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15352060"^^xsd:string) "Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3-hydroxy group of a quercetin molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "quercetin 7-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15352060"^^xsd:string) "Catalysis of the transfer of a glucosyl group from UDP-glucose to the 7-hydroxy group of a quercetin molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "quercetin 3'-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15352060"^^xsd:string) "Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3'-hydroxy group of a quercetin molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "quercetin 4'-O-glucosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15352060"^^xsd:string) "Catalysis of the transfer of a glucosyl group from UDP-glucose to the 4'-hydroxy group of a quercetin molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:18463094"^^xsd:string) "Catalysis of the reaction: GDP-L-galactose + phosphate = L-galactose-1-P + GDP."^^xsd:string) AnnotationAssertion(rdfs:label "GDP-L-galactose phosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:18463094"^^xsd:string) "Catalysis of the reaction: GDP-D-glucose + phosphate = D-glucose-1-P + GDP."^^xsd:string) AnnotationAssertion(rdfs:label "GDP-D-glucose phosphorylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:18190525"^^xsd:string) "Catalysis of the reaction: L-gulono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c."^^xsd:string) AnnotationAssertion(rdfs:label "L-gulono-1,4-lactone dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19050168"^^xsd:string) "Catalysis of the transfer of nitrate ions (NO3-) from one side of a membrane to the other. In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations."^^xsd:string) AnnotationAssertion(rdfs:label "low affinity nitrate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "flavonol 3-O-arabinosyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18757557"^^xsd:string) "Catalysis of the reaction: UDP-arabinose + a flavonol = UDP + a flavonol 3-O-D-arabinoside."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.5.1"^^xsd:string) Annotation( "MetaCyc:RXN-1404"^^xsd:string) "Catalysis of the reaction: indole-3-acetonitrile + 2 H2O = indole-3-acetic acid + NH3."^^xsd:string) AnnotationAssertion(rdfs:label "indole-3-acetonitrile nitrilase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "KEGG:R08369"^^xsd:string) Annotation( "PMID:15342621"^^xsd:string) "Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-9-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event."^^xsd:string) AnnotationAssertion(rdfs:label "cytokinin 9-beta-glucosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:14653780"^^xsd:string) "Catalysis of the reaction: 4,4-dimethyl-9beta,19-cyclopropylsterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy, 4-beta-methyl-9beta,19-cyclopropylsterol + 3 NADP+ + 3 H2O. This overall reaction proceeds through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH)."^^xsd:string) AnnotationAssertion(rdfs:label "4,4-dimethyl-9beta,19-cyclopropylsterol-4alpha-methyl oxidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-alpha-methyl-delta7-sterol-4alpha-methyl oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14653780"^^xsd:string) "Catalysis of the reaction: 4-alpha-methyl-delta7-sterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy,delta7-sterol + 3 NADP+ + 3 H2O. This overall reaction proceeds through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19077143"^^xsd:string) "Catalysis of the reaction: 3-methylthiopropyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 3-methylthiopropyl-glucosinolate + adenosine 3',5'-bisphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "3-methylthiopropyl-desulfoglucosinolate sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-methylthiobutyl-desulfoglucosinolate sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19077143"^^xsd:string) "Catalysis of the reaction: 4-methylthiobutyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 4-methylthiobutyl-glucosinolate + adenosine 3',5'-bisphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5-methylthiopentyl-desulfoglucosinolate sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19077143"^^xsd:string) "Catalysis of the reaction: 5-methylthiopentyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 5-methylthiopentyl-glucosinolate + adenosine 3',5'-bisphosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19077143"^^xsd:string) "Catalysis of the reaction: 7-methylthioheptyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 7-methylthioheptyl-glucosinolate + adenosine 3',5'-bisphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "7-methylthioheptyl-desulfoglucosinolate sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19077143"^^xsd:string) "Catalysis of the reaction: 8-methylthiooctyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 8-methylthiooctyl-glucosinolate + adenosine 3',5'-bisphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "8-methylthiooctyl-desulfoglucosinolate sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19077143"^^xsd:string) "Catalysis of the reaction: indol-3-yl-methyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = indol-3-yl-methyl-glucosinolate + adenosine 3',5'-bisphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "indol-3-yl-methyl-desulfoglucosinolate sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19077165"^^xsd:string) "Catalysis of the transfer of a sinapoyl group to a nitrogen atom on the spermidine molecule."^^xsd:string) AnnotationAssertion(rdfs:label "spermidine:sinapoyl CoA N-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19077165"^^xsd:string) "Catalysis of the transfer of a coumaroyl group to a nitrogen atom on the spermidine molecule."^^xsd:string) AnnotationAssertion(rdfs:label "spermidine:coumaroyl CoA N-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19077165"^^xsd:string) "Catalysis of the transfer of a caffeoyl group to a nitrogen atom on the spermidine molecule."^^xsd:string) AnnotationAssertion(rdfs:label "spermidine:caffeoyl CoA N-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19077165"^^xsd:string) "Catalysis of the transfer of a feruloyl group to a nitrogen atom on the spermidine molecule."^^xsd:string) AnnotationAssertion(rdfs:label "spermidine:feruloyl CoA N-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "caffeoyl CoA:S-adenosyl-L-methionine O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19077165"^^xsd:string) "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a caffeoyl CoA molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "trihydroxyferuloyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19077165"^^xsd:string) "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a trihydroxyferuloyl spermidine molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tricaffeoyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19077165"^^xsd:string) "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a tricaffeoyl spermidine molecule."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cellobiose glucosidase activity"^^xsd:string) AnnotationAssertion( "cellobiose glucohydrolase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15604686"^^xsd:string) "Catalysis of the reaction: cellobiose + H2O = 2 D-glucose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-methylumbelliferyl-beta-D-glucopyranoside beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15604686"^^xsd:string) "Catalysis of the hydrolysis of glucosidic link in 4-methylumbelliferyl-beta-D-glucopyranoside."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:15604686"^^xsd:string) "Catalysis of the hydrolysis of glucosidic link in esculin."^^xsd:string) AnnotationAssertion(rdfs:label "esculin beta-glucosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "beta-gentiobiose beta-glucosidase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15604686"^^xsd:string) "Catalysis of the hydrolysis of glucosidic link in beta-gentiobiose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:12711688"^^xsd:string) "Interacting selectively and non-covalently with the 5S rDNA sequence encoding ribosomal 5S rRNA, which is individually transcribed by RNA polymerase III, rather than by RNA polymerase I, in species where it exists."^^xsd:string) AnnotationAssertion(rdfs:label "5S rDNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19168716"^^xsd:string) "Catalysis of the transfer of a sinapoyl group to a nitrogen atom on the spermidine molecule."^^xsd:string) AnnotationAssertion(rdfs:label "sinapoyl spermidine:sinapoyl CoA N-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidylethanolamine-sterol O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16020547"^^xsd:string) "Catalysis of the reaction: a phosphatidylethanolamine + a sterol = a sterol ester + a lysophosphatidylethanolamine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16020547"^^xsd:string) "Catalysis of the reaction: a phosphatidate + a sterol = a sterol ester + a lysophosphatidate."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidate-sterol O-acyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-10139"^^xsd:string) "Catalysis of the reaction: L-tryptophan + pyruvate = 3-(indol-3-yl)pyruvate + L-alanine."^^xsd:string) AnnotationAssertion(rdfs:label "L-tryptophan:pyruvate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN3O-4157"^^xsd:string) "Catalysis of the reaction: L-tyrosine + pyruvate = (4-hydroxyphenyl)pyruvate + L-alanine."^^xsd:string) AnnotationAssertion(rdfs:label "L-tyrosine:pyruvate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-methionine:alpha-ketoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-methionine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18394996"^^xsd:string) "Catalysis of the reaction: L-methionine + 2-oxoglutarate = 4-methylthio-2-oxobutyrate + L-glutamate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:18394996"^^xsd:string) "Catalysis of the reaction: L-glutamine + 2-oxoglutarate = 2-oxoglutaramate + L-glutamate."^^xsd:string) AnnotationAssertion(rdfs:label "L-glutamine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion( "L-glutamine:alpha-ketoglutarate aminotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidyl-N-dimethylethanolamine N-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.71"^^xsd:string) Annotation( "PMID:19366698"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-dimethylethanolamine = S-adenosyl-L-homocysteine + phosphatidylcholine."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:18799661"^^xsd:string) "Catalysis of the reaction: 3-methylthiopropyl-glucosinolate = 3-methylsulfinylpropyl-glucosinolate."^^xsd:string) AnnotationAssertion(rdfs:label "3-methylthiopropyl glucosinolate S-oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:18799661"^^xsd:string) "Catalysis of the reaction: 4-methylthiopropyl-glucosinolate = 4-methylsulfinylpropyl-glucosinolate."^^xsd:string) AnnotationAssertion(rdfs:label "4-methylthiopropyl glucosinolate S-oxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5-methylthiopropyl glucosinolate S-oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18799661"^^xsd:string) "Catalysis of the reaction: 5-methylthiopropyl-glucosinolate = 5-methylsulfinylpropyl-glucosinolate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "6-methylthiopropyl glucosinolate S-oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18799661"^^xsd:string) "Catalysis of the reaction: 6-methylthiopropyl-glucosinolate = 6-methylsulfinylpropyl-glucosinolate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "7-methylthiopropyl glucosinolate S-oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18799661"^^xsd:string) "Catalysis of the reaction: 7-methylthiopropyl-glucosinolate = 7-methylsulfinylpropyl-glucosinolate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "8-methylthiopropyl glucosinolate S-oxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18799661"^^xsd:string) "Catalysis of the reaction: 8-methylthiopropyl-glucosinolate = 8-methylsulfinylpropyl-glucosinolate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "S-alkylthiohydroximate lyase activity"^^xsd:string) AnnotationAssertion( "S-alkylthiohydroximate C-S lyase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:14871316"^^xsd:string) "Catalysis of the conversion of a S-alkylthiohydroximate to a thiohydroximate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "indole-3-acetonitrile nitrile hydratase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:4.2.1.84"^^xsd:string) Annotation( "MetaCyc:RXN-7567"^^xsd:string) Annotation( "PMID:11607511"^^xsd:string) Annotation( "PMID:12430025"^^xsd:string) "Catalysis of the reaction: indole-3-acetonitrile + H2O = indole-3-acetamide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:18703495"^^xsd:string) "Interacting selectively and non-covalently with the tail region of a myosin XI heavy chain."^^xsd:string) AnnotationAssertion(rdfs:label "myosin XI tail binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:18980649"^^xsd:string) "Catalysis of the transfer of glucuronate to the xylan backbone of glucuronoxylan molecule."^^xsd:string) AnnotationAssertion(rdfs:label "glucuronoxylan glucuronosyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "brassinosteroid sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:22921"^^xsd:string) Annotation( "PMID:10409637"^^xsd:string) Annotation( "PMID:17039368"^^xsd:string) "Catalysis of the reaction: a brassinosteroid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated brassinosteroid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a brassinosteroid acceptor, producing the sulfated brassinosteroid derivative."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "adenosine monophosphate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "AMP transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18923018"^^xsd:string) "Catalysis of the transfer of AMP, adenosine monophosphate, from one side of a membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "jasmonic acid-amino synthetase activity"^^xsd:string) AnnotationAssertion( "jasmonate-amino acid synthetase activity"^^xsd:string) AnnotationAssertion( "jasmonate-amido synthetase activity"^^xsd:string) AnnotationAssertion( "jasmonyl-amino synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:15258265"^^xsd:string) Annotation( "PMID:17291501"^^xsd:string) "Catalysis of the reaction: jasmonate + an amino acid = an amide-linked jasmonyl-amino acid conjugate. The substrates of this reaction include non-standard amino acids, such as ACC (1-aminocyclopropane-1-carboxylate)."^^xsd:string) AnnotationAssertion( "ja-amino synthetase activity"^^xsd:string) AnnotationAssertion( "jasmonate-amino acid conjugate synthetase activity"^^xsd:string) AnnotationAssertion( "jasmonate:amino acid synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "jasmonate-amino synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "pheophytin pheophorbide hydrolase activity"^^xsd:string) AnnotationAssertion(rdfs:label "pheophytinase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19304936"^^xsd:string) "Catalysis of the reaction: pheophytin + H2O = phytol + pheophorbide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "L-phenylalanine:alpha-ketoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-phenylalanine:2-oxoglutarate aminotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pmn_curators"^^xsd:string) Annotation( "PMID:18394996"^^xsd:string) "Catalysis of the reaction: L-phenylalanine + 2-oxoglutarate = phenylpyruvate + L-glutamate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-10451"^^xsd:string) "12-hydroxyjasmonic acid sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.2.-"^^xsd:string) Annotation( "GOC:pmn_curators"^^xsd:string) Annotation( "MetaCyc:RXN-10451"^^xsd:string) Annotation( "MetaCyc:RXN-10453"^^xsd:string) Annotation( "PMID:12637544"^^xsd:string) "Catalysis of the reaction: a hydroxyjasmonate + 3'-phosphoadenosine-5'-phosphosulfate = a hydroxyjasmonate sulfate + adenosine-3',5'-diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10451"^^xsd:string) "12-OHJA sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10453"^^xsd:string) "11-hydroxyjasmonic acid sulfotransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "hydroxyjasmonate sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10451"^^xsd:string) "12-hydroxyjasmonate sulfotransferase activity"^^xsd:string) AnnotationAssertion( "OHJA sulfotransferase activity"^^xsd:string) AnnotationAssertion( "hydroxyjasmonic acid sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10453"^^xsd:string) "11-OHJA sulfotransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-10453"^^xsd:string) "11-hydroxyjasmonate sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "fatty acid 2-hydroxylase"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19054355"^^xsd:string) "Catalysis of the conversion of a fatty acid to an alpha-hydroxylated fatty acid. A hydroxyl group is added to the second carbon, counted from the carboxyl end, of a fatty acid chain."^^xsd:string) AnnotationAssertion(rdfs:label "fatty acid alpha-hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:17905869"^^xsd:string) "Catalysis of the conversion of an alkane to a secondary alcohol."^^xsd:string) AnnotationAssertion(rdfs:label "midchain alkane hydroxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "borate uptake transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "boron uptake transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18603465"^^xsd:string) "Catalysis of the transfer of borate from the outside of a cell to the inside of the cell across a membrane."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "borate efflux transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:18603465"^^xsd:string) "Catalysis of the transfer of borate from the inside of the cell to the outside of the cell across a membrane."^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "boron efflux transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-cysteine desulfhydrase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:LCYSDESULF-RXN"^^xsd:string) Annotation( "PMID:19955263"^^xsd:string) "Catalysis of the reaction: L-cysteine + H2O = ammonia + pyruvate + hydrogen sulfide + H+."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "S-adenosyl-L-methionine:benzoate carboxyl methyltransferase activity"^^xsd:string) AnnotationAssertion(rdfs:label "S-adenosyl-L-methionine:benzoic acid carboxyl methyl transferase activity"^^xsd:string) AnnotationAssertion(Annotation( "MetaCyc:RXN-6722"^^xsd:string) Annotation( "PMID:10852939"^^xsd:string) "Catalysis of the reaction: benzoate + S-adenosyl-L-methionine = methylbenzoate + S-adenosyl-L-homocysteine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "auxin transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19506555"^^xsd:string) "Catalysis of the transfer of auxins from one side of the membrane to the other. Auxins are plant hormones that regulate aspects of plant growth."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:20801759"^^xsd:string) "Catalysis of the hydrolysis of xyloglucan side chains so as to remove unsubstituted D-xylose residues attached to the glucose located at the non-reducing terminus."^^xsd:string) AnnotationAssertion(rdfs:label "xyloglucan 1,6-alpha-xylosidase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "voltage-gated sodium channel activity involved in cardiac muscle cell action potential"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "voltage-gated calcium channel activity involved in cardiac muscle cell action potential"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "A wide pore channel activity that enables a direct cytoplasmic connection from an SA node cell to an atrial cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction."^^xsd:string) AnnotationAssertion( "gap junction channel activity involved in SAN cell-atrial cardiomyocyte electrical coupling"^^xsd:string) AnnotationAssertion( "gap junction channel activity involved in sinoatrial node cell-atrial cardiomyocyte electrical coupling"^^xsd:string) AnnotationAssertion(rdfs:label "gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling"^^xsd:string) AnnotationAssertion( "gap junction channel activity involved in sinus node cell-atrial cardiomyocyte electrical coupling"^^xsd:string) AnnotationAssertion( "gap junction channel activity involved in SA node cell-atrial cardiomyocyte electrical coupling"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sodium:potassium-exchanging ATPase activity involved in regulation of cardiac muscle cell membrane potential"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in), that contributes to regulating the membrane potential of a cardiac muscle cell."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in), which contributes to regulating the membrane potential of a cardiac muscle cell."^^xsd:string) AnnotationAssertion(rdfs:label "calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a cardiac muscle cell plasma membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans). The transfer contributes to the regulation of the plasma membrane potential."^^xsd:string) AnnotationAssertion(rdfs:label "calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a cardiac muscle cell membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). This transfer contributes to the regulation of the cardiac muscle cell plasma membrane potential."^^xsd:string) AnnotationAssertion(rdfs:label "sodium:hydrogen antiporter activity involved in regulation of cardiac muscle cell membrane potential"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "voltage-gated potassium channel activity involved in sinoatrial node cell action potential depolarization"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion(rdfs:label "voltage-gated potassium channel activity involved in SA node cell action potential depolarization"^^xsd:string) AnnotationAssertion( "voltage-gated potassium channel activity involved in sinus node cell action potential depolarization"^^xsd:string) AnnotationAssertion( "voltage-gated potassium channel activity involved in SAN cell action potential depolarization"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an AV node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion( "voltage-gated calcium channel activity involved in AV node cardiac muscle cell action potential"^^xsd:string) AnnotationAssertion(rdfs:label "voltage-gated calcium channel activity involved in AV node cell action potential"^^xsd:string) AnnotationAssertion( "voltage-gated calcium channel activity involved in atrioventricular node cardiac muscle cell action potential"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "voltage-gated calcium channel activity involved in bundle of His cell action potential"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a bundle of His cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion( "voltage-gated calcium channel activity involved in bundle of His cardiac muscle cell action potential"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an Purkinje myocyte cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion(rdfs:label "voltage-gated calcium channel activity involved in Purkinje myocyte cell action potential"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "voltage-gated calcium channel activity involved in SAN cardiac muscle cell action potential"^^xsd:string) AnnotationAssertion(rdfs:label "voltage-gated calcium channel activity involved SA node cell action potential"^^xsd:string) AnnotationAssertion( "voltage-gated calcium channel activity involved in sinus node cardiac muscle cell action potential"^^xsd:string) AnnotationAssertion( "voltage-gated calcium channel activity involved in sinoatrial node cardiac muscle cell action potential"^^xsd:string) AnnotationAssertion( "voltage-gated calcium channel activity involved in SA node cardiac muscle cell action potential"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an SA node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion( "voltage-gated sodium channel activity involved in atrioventricular node cardiac muscle cell action potential"^^xsd:string) AnnotationAssertion(rdfs:label "voltage-gated sodium channel activity involved in AV node cell action potential"^^xsd:string) AnnotationAssertion( "voltage-gated sodium channel activity involved in AV node cardiac muscle cell action potential"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "voltage-gated sodium channel activity involved in bundle of His cardiac muscle cell action potential"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a bundle of His cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion(rdfs:label "voltage-gated sodium channel activity involved in bundle of His cell action potential"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion(rdfs:label "voltage-gated sodium channel activity involved in Purkinje myocyte action potential"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion( "voltage-gated sodium channel activity involved in sinoatrial node cardiac muscle cell action potential"^^xsd:string) AnnotationAssertion( "voltage-gated sodium channel activity involved in SAN cardiac muscle cell action potential"^^xsd:string) AnnotationAssertion(rdfs:label "voltage-gated sodium channel activity involved in SA node cell action potential"^^xsd:string) AnnotationAssertion( "voltage-gated sodium channel activity involved in sinus node cardiac muscle cell action potential"^^xsd:string) AnnotationAssertion( "voltage-gated sodium channel activity involved in SA node cardiac muscle cell action potential"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "A wide pore channel activity that enables a direct cytoplasmic connection from one cardiomyocyte to an adjacent cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction."^^xsd:string) AnnotationAssertion(rdfs:label "gap junction channel activity involved in cardiac conduction electrical coupling"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "gap junction channel activity involved in atrial cardiomyocyte-AV node cell electrical coupling"^^xsd:string) AnnotationAssertion(rdfs:label "gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling"^^xsd:string) AnnotationAssertion( "gap junction channel activity involved in atrial cardiomyocyte-atrioventricular node cell electrical coupling"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "A wide pore channel activity that enables a direct cytoplasmic connection from an atrial cardiomyocyte to an AV node cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "A wide pore channel activity that enables a direct cytoplasmic connection from an AV node cell to a bundle of His cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction."^^xsd:string) AnnotationAssertion( "gap junction channel activity involved in atrioventricular node cell-bundle of His cell electrical coupling"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "A wide pore channel activity that enables a direct cytoplasmic connection from a bundle of His cell to a Purkinje myocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction."^^xsd:string) AnnotationAssertion(rdfs:label "gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "A wide pore channel activity that enables a direct cytoplasmic connection from a Purkinje myocyte to a ventricular cardiac muscle cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction."^^xsd:string) AnnotationAssertion(rdfs:label "gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Interacting selectively and non-covalently with any protein or protein complex contributing to the adhesion of two different types of cells."^^xsd:string) AnnotationAssertion(rdfs:label "cell adhesion mediator"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "cell adhesive protein binding involved in atrial cardiomyocyte-AV node cell communication"^^xsd:string) AnnotationAssertion( "cell adhesive protein binding involved in atrial cardiomyocyte-atrioventricular node cell communication"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Interacting selectively and non-covalently with any protein or protein complex that results in the connection of an atrial cardiomyocyte with an AV node cell and contributes to the communication between the two cells."^^xsd:string) AnnotationAssertion(rdfs:label "cell adhesive protein binding involved in atrial cardiac muscle cell-AV node cell communication"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Interacting selectively and non-covalently with any protein or protein complex that results in the connection of an AV node cell with a bundle of His cell and contributes to the communication between the two cells."^^xsd:string) AnnotationAssertion( "cell adhesive protein binding involved in atrioventricular node cell-bundle of His cell communication"^^xsd:string) AnnotationAssertion(rdfs:label "cell adhesive protein binding involved in AV node cell-bundle of His cell communication"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Interacting selectively and non-covalently with any protein or protein complex that results in the connection of a bundle of His cell with a Purkinje myocyte and contributes to the communication between the two cells."^^xsd:string) AnnotationAssertion(rdfs:label "cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Interacting selectively and non-covalently with any protein or protein complex that results in the connection of a Purkinje myocyte with an ventricular cardiac muscle cell and contributes to the communication between the two cells."^^xsd:string) AnnotationAssertion(rdfs:label "cell adhesive protein binding involved in Purkinje myocyte-ventricular cardiac muscle cell communication"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "cell adhesive protein binding involved in SA cardiomyocyte-atrial cardiomyocyte communication"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Interacting selectively and non-covalently with any protein or protein complex that results in the connection of an SA cardiomyocyte with an atrial cardiomyocyte and contributes to the communication between the two cells."^^xsd:string) AnnotationAssertion(rdfs:label "cell adhesive protein binding involved in SA cardiac muscle cell-atrial cardiac muscle cell communication"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "voltage-gated potassium channel activity involved in AV node cell action potential repolarization"^^xsd:string) AnnotationAssertion( "voltage-gated potassium channel activity involved in AV node cardiac muscle cell action potential repolarization"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion( "voltage-gated potassium channel activity involved in atrioventricular node cardiac muscle cell action potential"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a bundle of His cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "voltage-gated potassium channel activity involved in Purkinje myocyte action potential repolarization"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an atrial cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion( "voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "voltage-gated potassium channel activity involved in SA node cell action potential repolarization"^^xsd:string) AnnotationAssertion( "voltage-gated potassium channel activity involved in SAN cell action potential"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) "Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion( "voltage-gated potassium channel activity involved in sinus node cell action potential"^^xsd:string) AnnotationAssertion( "voltage-gated potassium channel activity involved in sinoatrial node cell action potential"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "translation regulator activity, nucleic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Any selective and non-covalent interaction with a nucleic acid involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "mitotic anaphase-promoting complex activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "A ubiquitin-protein ligase activity that increases the rate or extent of the metaphase to anaphase transition of the mitotic cell cycle."^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "ubiquitin-protein ligase activity involved in positive regulation of mitotic metaphase/anaphase transition"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Stops, prevents or reduces the activity of a polygalacturonase. Polygalacturonases catalyze the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans."^^xsd:string) AnnotationAssertion(rdfs:label "polygalacturonase inhibitor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ornithine carbamoyltransferase inhibitor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:jp"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) "Stops, prevents, or reduces ornithine carbamoyltransferase activity, the catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-12359"^^xsd:string) "Catalysis of the reaction: malonate + ATP + coenzyme A = malonyl-CoA + AMP + diphosphate."^^xsd:string) AnnotationAssertion(rdfs:label "malonyl-CoA synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "brassinosteroid binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Interacting selectively and non-covalently with a brassinosteroid."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) Annotation( "PMID:21934147"^^xsd:string) "Catalysis of the reaction: 7-hydroxymethyl chlorophyll a + 2 reduced ferredoxin + 2 H+ chlorophyll a + 2 oxidized ferredoxin + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "7-hydroxymethyl chlorophyll a reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nicotinate transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Enables the directed movement of nicotinate into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-methylnicotinate transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Enables the directed movement of N-methylnicotinate into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thiamine pyrophosphate transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "thiamine diphosphate transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Enables the directed movement of thiamine pyrophosphate into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:pz"^^xsd:string) "Catalysis of the reaction: caffeoyl-CoA + a saturated primary alcohol = an alkyl caffeate + CoA."^^xsd:string) AnnotationAssertion(rdfs:label "caffeoyl-CoA: alcohol caffeoyl transferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "myristoyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:18071249"^^xsd:string) "Catalysis of the reaction: ATP + myristic acid + CoA = AMP + diphosphate + myristoyl-CoA."^^xsd:string) AnnotationAssertion(rdfs:label "myristoyl-CoA ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:18071249"^^xsd:string) "Catalysis of the reaction: ATP + palmitic acid + CoA = AMP + diphosphate + palmitoyl-CoA."^^xsd:string) AnnotationAssertion( "palmitoyl-CoA synthetase activity"^^xsd:string) AnnotationAssertion(rdfs:label "palmitoyl-CoA ligase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oleoyl-CoA ligase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:18071249"^^xsd:string) "Catalysis of the reaction: ATP + oleic acid + CoA = AMP + diphosphate + oleoyl-CoA."^^xsd:string) AnnotationAssertion( "oleoyl-CoA synthetase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, camelliol-C-forming)"^^xsd:string) AnnotationAssertion(rdfs:label "camelliol C synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) Annotation( "PMID:17985917"^^xsd:string) "Catalyzes the reaction: (3S)-2,3-epoxy-2,3-dihydrosqualene = camelliol C."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-12183"^^xsd:string) Annotation( "PMID:21193570"^^xsd:string) "Catalyzes the reaction: a hydroxyacyl-CoA + 3 malonyl-CoA + 2 H+ = a hydroxylated tetraketide alpha-pyrone + 3 CO2 + 4 coenzyme A ."^^xsd:string) AnnotationAssertion(rdfs:label "tetraketide alpha-pyrone synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Enables the directed movement of abscisic acid into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion(rdfs:label "abscisic acid transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycerol-3-phosphate 2-O-acyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.3.1.198"^^xsd:string) "Catalysis of the reaction: an acyl-CoA + sn-glycerol 3-phosphate = CoA + a 2-acyl-sn-glycerol 3-phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucosinolate:hydrogen symporter activity"^^xsd:string) AnnotationAssertion( "glucosinolate:proton symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:22864417"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucosinolate(out) + H+(out) = glucosinolate(in) + H+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "IDPase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:22849572"^^xsd:string) "Catalysis of the reaction: IDP + H2O = IMP + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "inosine-diphosphatase activity"^^xsd:string) AnnotationAssertion( "inosine diphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "9,15,9'-tri-cis-zeta-carotene isomerase activity"^^xsd:string) AnnotationAssertion( "9,15,9'-tricis-zeta-carotene cis-trans-isomerase"^^xsd:string) AnnotationAssertion(Annotation( "EC:5.2.1.12"^^xsd:string) "Catalysis of the reaction: 9,15,9'-tricis-zeta-carotene = 9,9'-dicis-zeta-carotene."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "vitamin transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Enables the transfer of a vitamin from one side of a membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:22988102"^^xsd:string) "Catalysis of the reaction: phosphatidylglycerol + phosphatidylethanolamine = cardiolipin + ethanolamine."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylglycerol-phosphatidylethanolamine phosphatidyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "cardiolipin synthase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "drug transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Enables the directed movement of a drug into, out of or within a cell, or between cells. A drug is any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "small RNA 2'-O-methyltransferase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.1.1.n8"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a nucleoside residue in a small RNA molecule. Reaction: S-adenosyl-L-methionine + small RNA <=> S-adenosyl-L-homocysteine + small RNA containing a 3'-terminal 2'-O-methylnucleotide."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "GOC:tb"^^xsd:string) Annotation( "PMID:12352953"^^xsd:string) Annotation( "Pfam:PF00659"^^xsd:string) "Interacting selectively and non-covalently with a polo box domain of a protein. The polo box domain is involved in binding substrates of polo kinases."^^xsd:string) AnnotationAssertion(rdfs:label "polo box domain specific binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "tryptophan N-monooxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating)"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.125"^^xsd:string) Annotation( "KEGG:R08160"^^xsd:string) "Catalyzes the multi-step reaction: L-Tryptophan + 2 Oxygen + 2 NADPH + 2 H+ = Indole-3-acetaldehyde oxime + 3 H2O + 2 NADP+ + CO2. The individual reactions are: (1a) L-tryptophan + O2 + NADPH + H+ = N-hydroxy-L-tryptophan + NADP+ + H2O,(1b) N-hydroxy-L-tryptophan + O2 + NADPH + H+ = N,N-dihydroxy-L-tryptophan + NADP+ + H2O, and (1c) N,N-dihydroxy-L-tryptophan = (E)-indol-3-ylacetaldoxime + CO2 + H2O."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R09583"^^xsd:string) "Catalyzes the reaction: L-Tryptophan + Oxygen + NADPH + H+ = N-Hydroxy-L-tryptophan + NADP+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N-hydroxy-L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating)"^^xsd:string) AnnotationAssertion(Annotation( "KEGG:R09584"^^xsd:string) "Catalyzes the reaction: N-Hydroxy-L-tryptophan + Oxygen + NADPH + H+ = N,N-Dihydroxy-L-tryptophan + NADP+ + H2O."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "KEGG:R09585"^^xsd:string) "Catalyzes the reaction: N,N-Dihydroxy-L-tryptophan = Indole-3-acetaldehyde oxime + CO2 + H2O."^^xsd:string) AnnotationAssertion(rdfs:label "N,N-Dihydroxy-L-tryptophan decarboxylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pimelyl-[acyl-carrier protein] methyl ester esterase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:3.1.1.85"^^xsd:string) Annotation( "PMID:23045647"^^xsd:string) "Catalysis of the reaction: pimelyl-[acyl-carrier protein] methyl ester + H2O = pimelyl-[acyl-carrier protein] + methanol."^^xsd:string) AnnotationAssertion( "pimelyl-[acyl-carrier protein] methyl ester hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cytochrome-b5 reductase activity, acting on NADPH"^^xsd:string) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome b(5) = NADP+ + 2 ferrocytochrome b(5)."^^xsd:string) AnnotationAssertion( "cytochrome-b5 reductase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:tb"^^xsd:string) "Catalysis of the reaction: NADH + H+ + 2 ferricytochrome b(5) = NAD+ + 2 ferrocytochrome b(5)."^^xsd:string) AnnotationAssertion( "cytochrome b5 reductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cytochrome-b5 reductase activity, acting on NADH"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:pm"^^xsd:string) Annotation( "InterPro:IPR007330"^^xsd:string) "Interacting selectively and non-covalently with the MIT domain of a protein. The MIT domain is found in vacuolar sorting proteins, spastin (probable ATPase involved in the assembly or function of nuclear protein complexes), and a sorting nexin, which may play a role in intracellular trafficking."^^xsd:string) AnnotationAssertion(rdfs:label "MIT domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ELYC domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pm"^^xsd:string) Annotation( "PMID:18032582"^^xsd:string) Annotation( "PMID:19525971"^^xsd:string) "Interacting selectively and non-covalently with the ELYC domain of a protein. The ELYC domain is an approximately 150 amino acid sequence which contains a highly conserved tetrapeptide sequence, ELYC."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:64612"^^xsd:string) Annotation( "GOC:ab"^^xsd:string) Annotation( "PMID:16452632"^^xsd:string) Annotation( "RHEA:38584"^^xsd:string) "Catalysis of the movement of phosphatidylcholine from one membrane bilayer leaflet to the other, driven by the hydrolysis of ATP."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylcholine-translocating ATPase activity"^^xsd:string) AnnotationAssertion( "phosphatidylcholine flippase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:64612"^^xsd:string) Annotation( "GOC:ab"^^xsd:string) Annotation( "PMID:16452632"^^xsd:string) Annotation( "RHEA:36440"^^xsd:string) "Catalysis of the movement of phosphatidylethanolamine from one membrane bilayer leaflet to the other, driven by the hydrolysis of ATP."^^xsd:string) AnnotationAssertion( "phosphatidylethanolamine flippase activity"^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylethanolamine-translocating ATPase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidylserine-translocating ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:57262"^^xsd:string) Annotation( "GOC:ab"^^xsd:string) Annotation( "PMID:16452632"^^xsd:string) Annotation( "PMID:20224745"^^xsd:string) Annotation( "RHEA:38568"^^xsd:string) "Catalysis of the movement of phosphatidylserine from one membrane bilayer leaflet to the other, driven by the hydrolysis of ATP."^^xsd:string) AnnotationAssertion( "phosphatidylserine flippase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ceramide binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:17761"^^xsd:string) Annotation( "GOC:sart"^^xsd:string) "Interacting selectively and non-covalently with any ceramide, a class of lipids that is composed of sphingosine linked to a fatty acid. Ceramides are a major component of cell membranes."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "AKH receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:11904407"^^xsd:string) "Combining with an adipokinetic hormone to initiate a change in cell activity. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis."^^xsd:string) AnnotationAssertion(rdfs:label "adipokinetic hormone receptor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "AKH binding"^^xsd:string) AnnotationAssertion(rdfs:label "adipokinetic hormone binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:11904407"^^xsd:string) "Interacting selectively and non-covalently with an adipokinetic hormone. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:11904407"^^xsd:string) "Interacting selectively and non-covalently with an adipokinetic hormone receptor. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis."^^xsd:string) AnnotationAssertion(rdfs:label "adipokinetic hormone receptor binding"^^xsd:string) AnnotationAssertion( "AKH receptor binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "TMTT synthase activity"^^xsd:string) AnnotationAssertion(rdfs:label "4,8,12-trimethyltrideca-1,3,7,11-tetraene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) Annotation( "MetaCyc:RXN-8620"^^xsd:string) Annotation( "PMID:21088219"^^xsd:string) "Catalysis of the reaction: (EE)-geranyllinalool + NADPH + O2 = 4,8,12-trimethyl-1,3,7,11-tridecatetraene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C18-farnesylacetone and then cleaved to produce 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) and acetone."^^xsd:string) AnnotationAssertion( "4,8,12-trimethyl-1,3,7,11-tridecatetraene synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(3E)-4,8-dimethyl-1,3,7-nonatriene synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:kad"^^xsd:string) Annotation( "MetaCyc:RXN-8619"^^xsd:string) Annotation( "PMID:21088219"^^xsd:string) "Catalysis of the reaction: (E)-nerolidol + NADPH + O2 = (3E)-4,8-dimethylnona-1,3,7-triene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C11-geranylacetone and then cleaved to produce (3E)-4,8-dimethylnona-1,3,7-triene (DMNT) and acetone."^^xsd:string) AnnotationAssertion( "(3E)-4,8-dimethylnona-1,3,7-triene synthase activity"^^xsd:string) AnnotationAssertion( "DMNT synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "PMID:15241471"^^xsd:string) Annotation( "PMID:17237226"^^xsd:string) Annotation( "Prosite:PDOC51022"^^xsd:string) "Interacting selectively and non-covalently with a L27 domain of a protein. L27 is composed of conserved negatively charged amino acids and a conserved aromatic amino acid. L27 domains can assemble proteins involved in signaling and establishment and maintenance of cell polarity into complexes by interacting in a heterodimeric manner."^^xsd:string) AnnotationAssertion(rdfs:label "L27 domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "COPII adaptor activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rb"^^xsd:string) Annotation( "PMID:16957051"^^xsd:string) Annotation( "PMID:20236934"^^xsd:string) "The binding activity of a molecule that brings together the COPII vesicle proteins and one or more other molecules, permitting them to function in a coordinated way."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "PMID:11120740"^^xsd:string) Annotation( "PMID:21290439"^^xsd:string) "Catalysis of the reaction: D-fructose-6-phosphate = dihydroxyacetone + D-glyceraldehyde-3-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "fructose 6-phosphate aldolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ubiquitin-protein ligase activator activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rb"^^xsd:string) Annotation( "PMID:18321851"^^xsd:string) "Increases the activity of a ubiquitin-protein ligase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "centromere-specific nucleosome binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:jp"^^xsd:string) Annotation( "PMID:21412236"^^xsd:string) "Interacting selectively and non-covalently with a centromere-specific nucleosome, a form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3)."^^xsd:string) AnnotationAssertion( "centromeric nucleosome binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:rs"^^xsd:string) Annotation( "PMID:19456862"^^xsd:string) "Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of cadmium (Cd++)."^^xsd:string) AnnotationAssertion(rdfs:label "cadmium ion sensor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:rs"^^xsd:string) Annotation( "PMID:19928961"^^xsd:string) "Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of copper(I) (Cu+)."^^xsd:string) AnnotationAssertion(rdfs:label "copper ion sensor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "selenite:H+ symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mcc"^^xsd:string) Annotation( "PMID:20861301"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: selenite(out) + H+(out) = selenite(in) + H+(in)."^^xsd:string) AnnotationAssertion(rdfs:label "selenite:hydrogen symporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA/RNA hybrid annealing activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "PMID:21699496"^^xsd:string) "Facilitates the base-pairing of single-stranded RNA to double-stranded DNA resulting in the formation of R-loops."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:jj"^^xsd:string) Annotation( "Wikipedia:Albumen"^^xsd:string) "The action of a molecule that contributes to the structural integrity of albumen (also called egg white). Albumen is the clear liquid contained within an egg and consists of water and proteins, among which are ovomucin and ovomucoid. It protects the egg yolk and provides additional nutrition for the growth of the embryo."^^xsd:string) AnnotationAssertion(rdfs:label "structural constituent of albumen"^^xsd:string) AnnotationAssertion( "structural constituent of egg white"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "supercoiled DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pr"^^xsd:string) Annotation( "GOC:rph"^^xsd:string) Annotation( "PMID:20723754"^^xsd:string) Annotation( "PMID:21345933"^^xsd:string) Annotation( "Wikipedia:DNA_supercoil"^^xsd:string) "Interacting selectively and non-covalently with supercoiled DNA. For example, during replication and transcription, template DNA is negatively supercoiled in the receding downstream DNA and positively supercoiled in the approaching downstream DNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) Annotation( "PMID:10050855"^^xsd:string) "Interacting selectively and non-covalently with a member of the hedgehog protein family, signaling proteins involved in development."^^xsd:string) AnnotationAssertion(rdfs:label "hedgehog family protein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) Annotation( "GOC:sjp"^^xsd:string) Annotation( "PMID:21424692"^^xsd:string) "Interacting selectively and non-covalently with a member of the neuroligin protein family, neuronal cell surface proteins that mediate synapse formation."^^xsd:string) AnnotationAssertion(rdfs:label "neuroligin family protein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "scaffold protein binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:sjp"^^xsd:string) Annotation( "PMID:10433269"^^xsd:string) Annotation( "Wikipedia:Scaffold_protein"^^xsd:string) "Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cysteine-type endopeptidase activity involved in apoptotic process"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_apoptosis"^^xsd:string) "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process."^^xsd:string) AnnotationAssertion( "caspase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_apoptosis"^^xsd:string) "metacaspase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pre-mRNA intronic binding"^^xsd:string) AnnotationAssertion( "pre-messenger RNA intronic binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ans"^^xsd:string) Annotation( "PMID:16260624"^^xsd:string) "Interacting selectively and non-covalently with an intronic sequence of a pre-messenger RNA (pre-mRNA)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pre-mRNA intronic pyrimidine-rich binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ans"^^xsd:string) Annotation( "PMID:16260624"^^xsd:string) Annotation( "PMID:16777844"^^xsd:string) "Interacting selectively and non-covalently with a pyrimidine-rich (CU-rich) intronic sequence of a pre-messenger RNA (pre-mRNA)."^^xsd:string) AnnotationAssertion( "pre-messenger RNA intronic pyrimidine-rich binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "organic cyclic compound binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:33832"^^xsd:string) Annotation( "GOC:sjw"^^xsd:string) Annotation( "PMID:7583672"^^xsd:string) "Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "PCB binding"^^xsd:string) AnnotationAssertion( "polychlorobiphenyl binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:53156"^^xsd:string) Annotation( "GOC:sjw"^^xsd:string) Annotation( "PMID:7583672"^^xsd:string) "Interacting selectively and non-covalently with a polychlorinated biphenyl (PCB), a biphenyl compound containing between 2 and 10 chlorine atoms attached to the two benzene rings."^^xsd:string) AnnotationAssertion(rdfs:label "polychlorinated biphenyl binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:yaf"^^xsd:string) Annotation( "InterPro:IPR000219"^^xsd:string) Annotation( "PMID:12775584"^^xsd:string) "Interacting selectively and non-covalently with a DH (Dbl homology) domain of a protein. The DH domain contains three structurally conserved regions separated by more variable regions. It is composed of 11 alpha helices that are folded into a flattened, elongated alpha-helix bundle in which two of the three conserved regions, conserved region 1 (CR1) and conserved region 3 (CR3), are exposed near the centre of one surface. CR1 and CR3, together with a part of alpha-6 and the DH/PH (pleckstrin homology) junction site, constitute the Rho GTPase interacting pocket."^^xsd:string) AnnotationAssertion(rdfs:label "DH domain binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "MADS box domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:yaf"^^xsd:string) Annotation( "InterPro:IPR002100"^^xsd:string) Annotation( "PMID:18296735"^^xsd:string) Annotation( "Wikipedia:MADS-box"^^xsd:string) "Interacting selectively and non-covalently with a MADS box domain, a protein domain that encodes the DNA-binding MADS domain. The MADS domain binds to DNA sequences of high similarity to the motif CC[A/T]6GG termed the CArG-box. MADS-domain proteins are generally transcription factors. The length of the MADS-box is in the range of 168 to 180 base pairs."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sulfur carrier activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:imk"^^xsd:string) Annotation( "PMID:16387657"^^xsd:string) "Enables the directed movement of sulfur into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ans"^^xsd:string) Annotation( "PMID:20739282"^^xsd:string) "Interacting selectively and non-covalently with any part of a mitochondrial ribosome, a ribosome found in the mitochondrion of a eukaryotic cell."^^xsd:string) AnnotationAssertion(rdfs:label "mitochondrial ribosome binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "cysteine-type endopeptidase activity involved in apoptotic signalling pathway"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_apoptosis"^^xsd:string) "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway."^^xsd:string) AnnotationAssertion( "apical caspase activity"^^xsd:string) AnnotationAssertion( "initiator caspase activity"^^xsd:string) AnnotationAssertion(rdfs:label "cysteine-type endopeptidase activity involved in apoptotic signaling pathway"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cysteine-type endopeptidase activity involved in execution phase of apoptosis"^^xsd:string) AnnotationAssertion( "executioner caspase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_apoptosis"^^xsd:string) "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the execution phase of apoptosis."^^xsd:string) AnnotationAssertion( "effector caspase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:17633"^^xsd:string) Annotation( "GOC:imk"^^xsd:string) Annotation( "PMID:15109491"^^xsd:string) Annotation( "PMID:16968770"^^xsd:string) Annotation( "PMID:18359660"^^xsd:string) "Interacting selectively and non-covalently with guanosine tetraphosphate (5'-ppGpp-3'), a guanosine bisphosphate having diphosphate groups at both the 3' and 5'-positions."^^xsd:string) AnnotationAssertion( "5'-ppGpp-3' binding"^^xsd:string) AnnotationAssertion(rdfs:label "guanosine tetraphosphate binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "flavonoid binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:47916"^^xsd:string) Annotation( "GOC:sl"^^xsd:string) Annotation( "PMID:20599706"^^xsd:string) "Interacting selectively and non-covalently with a flavonoid, a compound containing two or more aromatic rings, each bearing at least one aromatic hydroxyl and connected with a carbon bridge."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:5078"^^xsd:string) Annotation( "GOC:sl"^^xsd:string) "Interacting selectively and non-covalently with a flavonol, a flavonoid that contains a 3-hydroxy-2-phenylchromen-4-one backbone."^^xsd:string) AnnotationAssertion(rdfs:label "flavonol binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:24036"^^xsd:string) Annotation( "GOC:sl"^^xsd:string) "Interacting selectively and non-covalently with a flavanol."^^xsd:string) AnnotationAssertion( "flavan-3-ol binding"^^xsd:string) AnnotationAssertion(rdfs:label "flavanol binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:23053"^^xsd:string) Annotation( "GOC:sl"^^xsd:string) "Interacting selectively and non-covalently with a catechin, a polyphenolic antioxidant plant metabolite with a flavonoid or flavan-3-ol structure."^^xsd:string) AnnotationAssertion(rdfs:label "catechin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "epigallocatechin 3-gallate binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:4806"^^xsd:string) Annotation( "GOC:sl"^^xsd:string) Annotation( "PMID:21307292"^^xsd:string) "Interacting selectively and non-covalently with epigallocatechin 3-gallate, a compound that is a gallic acid ester of a catechin."^^xsd:string) AnnotationAssertion( "EGCG binding"^^xsd:string) AnnotationAssertion( "catechin gallate binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "(R)-3-hydroxybutyrate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "beta-hydroxybutyrate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "3-hydroxybutanoic acid transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:10983"^^xsd:string) Annotation( "GOC:dsf"^^xsd:string) Annotation( "PMID:22302940"^^xsd:string) "Catalysis of the transfer of beta-hydroxybutyrate from one side of the membrane to the other. Beta-hydroxybutyrate is the conjugate base of (R)-3-hydroxybutyric acid."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phenyllactate dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pde"^^xsd:string) Annotation( "PMID:15421980"^^xsd:string) "Catalysis of the oxidation of phenyllactate to produce phenylpyruvate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "leukotriene B4 12-hydroxydehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "leukotriene B4 12-hydroxy dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mw"^^xsd:string) Annotation( "KEGG:R03864"^^xsd:string) Annotation( "PMID:8394361"^^xsd:string) Annotation( "PMID:9461497"^^xsd:string) "Catalysis of the reaction: leukotriene B4 + NADP(+) = 12-oxo-leukotriene B4 + NADPH + H(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "20-hydroxy-leukotriene B4 omega-oxidation"^^xsd:string) AnnotationAssertion( "20-hydroxy-leukotriene B4 omega-oxidase activity"^^xsd:string) AnnotationAssertion(rdfs:label "20-hydroxy-leukotriene B4 omega oxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mw"^^xsd:string) Annotation( "PMID:2836406"^^xsd:string) "Catalysis of the reaction: 20-hydroxy-leukotriene B4 + O2 + NADPH + H(+) = 20-aldehyde-leukotriene B4 + 2H2O + NADP(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "20-aldehyde-leukotriene B4 20-monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mw"^^xsd:string) Annotation( "PMID:2549038"^^xsd:string) Annotation( "PMID:2836406"^^xsd:string) "Catalysis of the reaction: 20-aldehyde-leukotriene B4 + O2 + NADPH + H(+) = 20-carboxy-leukotriene B4 + H2O + NADP(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mw"^^xsd:string) Annotation( "PMID:18184802"^^xsd:string) Annotation( "PMID:18647347"^^xsd:string) "Catalysis of the reaction: leukotriene A4 = eoxin A4."^^xsd:string) AnnotationAssertion(rdfs:label "eoxin A4 synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "eoxin C4 synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mw"^^xsd:string) Annotation( "PMID:18184802"^^xsd:string) Annotation( "PMID:18647347"^^xsd:string) "Catalysis of the reaction: eoxin A4 + glutathione = eoxin C4."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "eoxin D4 synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mw"^^xsd:string) Annotation( "PMID:18184802"^^xsd:string) Annotation( "PMID:18647347"^^xsd:string) "Catalysis of the reaction: eoxin C4 = eoxin D4 + 5-L-glutamyl amino acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mw"^^xsd:string) Annotation( "PMID:18184802"^^xsd:string) Annotation( "PMID:18647347"^^xsd:string) "Catalysis of the reaction: eoxin D4 + H20 = eoxin E4 + glycine."^^xsd:string) AnnotationAssertion(rdfs:label "eoxin E4 synthase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "5-HETE dehydrogenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity"^^xsd:string) AnnotationAssertion( "5(S)-HETE dehydrogenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mw"^^xsd:string) Annotation( "PMID:1326548"^^xsd:string) "Catalysis of the reaction: 5-HETE + NADP(+) = 5-oxo-ETE + NADPH + H(+)."^^xsd:string) AnnotationAssertion( "5-hydroxy-eicosatetraenoic acid dehydrogenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phenylacetyl-CoA 1,2-epoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.149"^^xsd:string) "phenylacetyl-CoA monooxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "phenylacetyl-CoA epoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.149"^^xsd:string) "ring 1,2-phenylacetyl-CoA epoxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.14.13.149"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "GOC:gk"^^xsd:string) Annotation( "PMID:20660314"^^xsd:string) Annotation( "PMID:21247899"^^xsd:string) "Catalysis of the reaction: phenylacetyl-CoA + H(+) + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP(+)."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "all-trans-decaprenyl-diphosphate synthase activity"^^xsd:string) AnnotationAssertion( "2-trans,6-trans-farnesyl diphosphate activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.5.1.91"^^xsd:string) Annotation( "GOC:mw"^^xsd:string) Annotation( "PMID:16262699"^^xsd:string) "Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-decaprenyl diphosphate."^^xsd:string) AnnotationAssertion( "(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cysteine-type endopeptidase activity involved in plant-type hypersensitive response"^^xsd:string) AnnotationAssertion( "metacaspase activity involved in plant-type hypersensitive response"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mtg_apoptosis"^^xsd:string) "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to plant-type hypersensitive response, the rapid, localized death of plant cells in response to invasion by a pathogen."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "7SK snRNA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:nhn"^^xsd:string) Annotation( "PMID:21853533"^^xsd:string) "Interacting selectively and non-covalently with a 7SK small nuclear RNA (7SK snRNA)."^^xsd:string) AnnotationAssertion( "7SK small nuclear RNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "toxin-antitoxin pair type II binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:rs"^^xsd:string) Annotation( "PMID:19143615"^^xsd:string) Annotation( "PMID:19325885"^^xsd:string) Annotation( "PMID:21819231"^^xsd:string) Annotation( "PMID:22545240"^^xsd:string) Annotation( "http://en.wikipedia.org/wiki/Toxin-antitoxin_system#Type_II"^^xsd:string) "Interacting selectively and non-covalently with a toxic protein, disabling its function. There may be more than one antitoxin to a toxic protein. Instances of this activity are known only in prokaryotes, where the toxic protein may be a ribonuclease, a DNA gyrase, or other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:se"^^xsd:string) Annotation( "PMID:10918062"^^xsd:string) "Catalysis of the reaction: D-leucyl-tRNA(Leu) = D-leucine + tRNA(Leu). Hydrolysis of the removal of D-leucine from residues in charged tRNA(Leu)."^^xsd:string) AnnotationAssertion(rdfs:label "D-leucyl-tRNA(Leu) deacylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "O-GlcNAc transferase"^^xsd:string) AnnotationAssertion( "UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase"^^xsd:string) AnnotationAssertion( "OGTase"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.4.1.255"^^xsd:string) Annotation( "GOC:jsg"^^xsd:string) Annotation( "GOC:sart"^^xsd:string) Annotation( "PMID:22158438"^^xsd:string) "Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine, or UDP-N-acetyl-D-glucosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine."^^xsd:string) AnnotationAssertion(rdfs:label "protein O-GlcNAc transferase activity"^^xsd:string) AnnotationAssertion( "O-linked N-acetylglucosaminyltransferase "^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) Annotation( "PMID:21290758"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential."^^xsd:string) AnnotationAssertion(rdfs:label "stretch-activated, cation-selective, calcium channel activity involved in regulation of action potential"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) Annotation( "PMID:21290758"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential in a cardiac muscle cell."^^xsd:string) AnnotationAssertion(rdfs:label "stretch-activated, cation-selective, calcium channel activity involved in regulation of cardiac muscle cell action potential"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carbohydrate derivative binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:pr"^^xsd:string) "Interacting selectively and non-covalently with a carbohydrate derivative."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "InterPro:IPR016495"^^xsd:string) "Interacting selectively and non-covalently with any isoform of the MDM2/MDM4 protein family, comprising negative regulators of p53."^^xsd:string) AnnotationAssertion(rdfs:label "MDM2/MDM4 family protein binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.17"^^xsd:string) Annotation( "EC:3.5.1.98"^^xsd:string) Annotation( "GOC:sp"^^xsd:string) Annotation( "PMID:22722849"^^xsd:string) Annotation( "RHEA:24551"^^xsd:string) "Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 18) + H2O = histone H3 L-lysine (position 18) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 18 of the histone H3 protein."^^xsd:string) AnnotationAssertion(rdfs:label "NAD-dependent histone deacetylase activity (H3-K18 specific)"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:pde"^^xsd:string) "Catalysis of the reaction: a deoxynucleoside diphosphate + H2O = a deoxynucleotide + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "deoxynucleoside-diphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:pde"^^xsd:string) Annotation( "PMID:20385596"^^xsd:string) "Catalysis of the reaction: dIDP + H2O = dIMP + phosphate."^^xsd:string) AnnotationAssertion( "deoxyinosine-diphosphatase activity"^^xsd:string) AnnotationAssertion(rdfs:label "dIDP diphosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) "Catalysis of the ligation of an amino acid to another amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate, carried out by a nonribosomal peptide synthase."^^xsd:string) AnnotationAssertion(rdfs:label "amino acid ligation activity by nonribosomal peptide synthase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "succinate:hydrogen symporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:1293882"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + H+(out) = succinate(in) + H+(in)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cyclin-dependent protein tyrosine kinase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:1372994"^^xsd:string) "Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. This reaction requires the binding of a regulatory cyclin subunit."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:pr"^^xsd:string) "Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK)."^^xsd:string) AnnotationAssertion(rdfs:label "cyclin-dependent protein kinase activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "structural molecule activity conferring elasticity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) Annotation( "PMID:23283722"^^xsd:string) "The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell, providing elasticity and recoiling."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "deaminated base DNA glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:18789404"^^xsd:string) "DNA N-glycosylase activity acting on deaminated bases."^^xsd:string) AnnotationAssertion(rdfs:label "deaminated base DNA N-glycosylase activity"^^xsd:string) AnnotationAssertion( "DNA glycosylase activity acting on deaminated bases"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:18789404"^^xsd:string) "DNA N-glycosylase activity acting on deaminated adenine (hypoxanthine)."^^xsd:string) AnnotationAssertion(rdfs:label "hypoxanthine DNA N-glycosylase activity"^^xsd:string) AnnotationAssertion( "hypoxanthine-DNA glycosylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "xanthine-DNA glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:18789404"^^xsd:string) "DNA N-glycosylase activity acting on deaminated guanine (xanthine)."^^xsd:string) AnnotationAssertion(rdfs:label "xanthine DNA N-glycosylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "oxanine DNA N-glycosylase activity"^^xsd:string) AnnotationAssertion( "oxanine-DNA glycosylase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:18789404"^^xsd:string) "DNA N-glycosylase activity acting on deaminated guanine where the resulting base (oxanine) is generated by NO- or HNO2-induced nitrosative deamination."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "G-rich strand telomeric DNA binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11349150"^^xsd:string) "Interacting selectively and non-covalently with G-rich, single-stranded, telomere-associated DNA."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mah"^^xsd:string) "Catalysis of the reaction: phosphopolynucleotide + H2O = polynucleotide + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "polynucleotide phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nucleotide phosphatase activity, acting on free nucleotides"^^xsd:string) AnnotationAssertion( "nucleotide phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:dos"^^xsd:string) "Catalysis of the reaction: nucleotide + H2O = nucleotide + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dos"^^xsd:string) Annotation( "http://www.ecocyc.org/ECOLI/NEW-IMAGE?object=BC-3.1.2.3"^^xsd:string) "A DNA binding transcription factor activity that is directly regulated by binding of a ligand to the protein with this activity. Examples include the lac and trp repressors in E.coli and many steroid hormone receptors."^^xsd:string) AnnotationAssertion(rdfs:label "direct ligand regulated sequence-specific DNA binding transcription factor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dos"^^xsd:string) Annotation( "PMID:23910378"^^xsd:string) "Interacting selectively and non-covalently with c[G(2',5')pA(2',5')p], a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2',5' and 3',5' linkages."^^xsd:string) AnnotationAssertion(Annotation( "PMID:23910378"^^xsd:string) "c[G(2',5')pA(3',5')p] binding"^^xsd:string) AnnotationAssertion(rdfs:label "2',5-3',5'-cyclic GMP-AMP binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "oligopeptido binding"^^xsd:string) AnnotationAssertion(rdfs:label "oligopeptide binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Oligopeptid binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:21854595"^^xsd:string) "Interacting selectively and non-covalently with an oligopeptide."^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "oligopeptides binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:52971"^^xsd:string) Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:al"^^xsd:string) "Interacting selectively and non-covalently with ubiquinone-6. Ubiquinone-6 is a ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2."^^xsd:string) AnnotationAssertion(rdfs:label "ubiquinone-6 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:22699612"^^xsd:string) "Interacting selectively and non-covalently with salicylic acid."^^xsd:string) AnnotationAssertion(rdfs:label "salicylic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:22699612"^^xsd:string) "salicylic acid receptor"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(R)-carnitine transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:16365042"^^xsd:string) Annotation( "PMID:20357772"^^xsd:string) Annotation( "PMID:20829798"^^xsd:string) "Catalysis of the transfer of (R)-carnitine from one side of the membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:16952940"^^xsd:string) Annotation( "PMID:21784948"^^xsd:string) "Catalysis of the transfer of 4-(trimethylammonio)butanoate from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "4-(trimethylammonio)butanoate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tungstate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:16952940"^^xsd:string) Annotation( "PMID:21784948"^^xsd:string) "Catalysis of the transfer of tungstate from one side of the membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "tungstate transmembrane-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:16952940"^^xsd:string) Annotation( "PMID:21784948"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + tungstate(in) = ADP + phosphate + tungstate(out)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:9128730"^^xsd:string) Annotation( "PMID:9573154"^^xsd:string) "Catalysis of the transfer of malonate(1-) from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "malonate(1-) transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "4-hydroxyphenylacetate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:9315705"^^xsd:string) "Catalysis of the transfer of 4-hydroxyphenylacetate from one side of the membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "doxorubicin transmembrane-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:12057006"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + doxorubicin(in) = ADP + phosphate + doxorubicin(out)."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "methionine transmembrane-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:12169620"^^xsd:string) Annotation( "PMID:12819857"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + methionine(in) = ADP + phosphate + methionine(out)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "nucleoside phosphate binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Interacting selectively and non-covalently with nucleoside phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "catecholamine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Interacting selectively and non-covalently with catecholamine."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Interacting selectively and non-covalently with tungstate."^^xsd:string) AnnotationAssertion(rdfs:label "tungstate binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "heterocyclic compound binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Interacting selectively and non-covalently with heterocyclic compound."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "NAD transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "reduced nicotinamide adenine dinucleotide transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "oxidized nicotinamide adenine dinucleotide transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "nicotinamide adenine dinucleotide transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Catalysis of the transfer of NAD from one side of the membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Catalysis of the transfer of an acetate ester from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "acetate ester transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "azole transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Catalysis of the transfer of azole from one side of the membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carbohydrate transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Enables the directed movement of carbohydrate into, out of or within a cell, or between cells."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Catalysis of the transfer of amitrole from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "aminotriazole transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Catalysis of the transfer of benomyl from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "benomyl transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "RHEA:33658"^^xsd:string) "Enables the directed movement of oleate into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion(rdfs:label "oleate transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) "Enables the directed movement of carbohydrate derivative into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion(rdfs:label "carbohydrate derivative transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lipo-chitin oligosaccharide transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Catalysis of the transfer of lipo-chitin oligosaccharide from one side of the membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lipo-chitin oligosaccharide transmembrane-transporting ATPase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipo-chitin oligosaccharide(in) = ADP + phosphate + lipo-chitin oligosaccharide(out)."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Catalysis of the transfer of poly-beta-1,6-N-acetyl-D-glucosamine from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) Annotation( "PMID:22223481"^^xsd:string) "Interacting selectively and non-covalently with hypochlorite."^^xsd:string) AnnotationAssertion(rdfs:label "hypochlorite binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Catalysis of the transfer of malonic acid from the outside of a cell to the inside across a membrane."^^xsd:string) AnnotationAssertion(rdfs:label "malonic acid uptake transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "fatty acid derivative binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) "Interacting selectively and non-covalently with fatty acid derivative."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Catalysis of the transfer of tetrapeptide from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "tetrapeptide transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dethiobiotin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Interacting selectively and non-covalently with dethiobiotin."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Catalysis of the transfer of biotin from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "biotin transmembrane transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "dethiobiotin transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Catalysis of the transfer of dethiobiotin from one side of the membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:kmv"^^xsd:string) "Interacting selectively and non-covalently with phosphatidylglycerol."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylglycerol binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "cardiolipin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:kmv"^^xsd:string) "Interacting selectively and non-covalently with cardiolipin."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "organic hydroxy compound transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) "Catalysis of the transfer of organic hydroxy compound from one side of the membrane to the other."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "XTP binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Interacting selectively and non-covalently with XTP."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ITP binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Interacting selectively and non-covalently with ITP."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) "Catalysis of the transfer of phosphate from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "phosphate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sulfur-containing amino acid secondary active transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) "Catalysis of the transfer of sulfur-containing amino acid from one side of the membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) "Interacting selectively and non-covalently with a sulfur compound."^^xsd:string) AnnotationAssertion(rdfs:label "sulfur compound binding"^^xsd:string) AnnotationAssertion( "sulfur molecular entity binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) "Catalysis of the transfer of a sulfur compound from one side of the membrane to the other."^^xsd:string) AnnotationAssertion( "sulfur molecular entity transmembrane transporter activity"^^xsd:string) AnnotationAssertion(rdfs:label "sulfur compound transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Catalysis of the transfer of an arsenate ion from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "arsenate ion transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Interacting selectively and non-covalently with proton."^^xsd:string) AnnotationAssertion(rdfs:label "proton binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) "Catalysis of the transfer of salt from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "salt transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "leptomycin B binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "Interacting selectively and non-covalently with leptomycin B."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) Annotation( "PMID:22573892"^^xsd:string) "Any protein kinase activity that is involved in regulation of protein localization to cell division site involved in cytokinesis."^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "protein kinase activity involved in regulation of protein localisation to cell division site involved in cytokinesis"^^xsd:string) AnnotationAssertion(rdfs:label "protein kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "protamine kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "protamine kinase activity involved in regulation of protein localisation to cell division site involved in cytokinesis"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:pm"^^xsd:string) Annotation( "PMID:7730362"^^xsd:string) "Interacting selectively and non-covalently with proline."^^xsd:string) AnnotationAssertion(rdfs:label "proline binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "pmid:23382251"^^xsd:string) "Catalysis of the transfer of glycerate from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "glycerate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:23445487"^^xsd:string) "Interacting selectively and non-covalently with phosphatidylinositol phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "phosphatidylinositol phosphate binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "maltose binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:21566157"^^xsd:string) "Interacting selectively and non-covalently with maltose."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:16529801"^^xsd:string) "Interacting selectively and non-covalently with (25S)-Delta(4)-dafachronate."^^xsd:string) AnnotationAssertion(rdfs:label "(25S)-Delta(4)-dafachronate binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(25S)-Delta(7)-dafachronate binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:16529801"^^xsd:string) "Interacting selectively and non-covalently with (25S)-Delta(7)-dafachronate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcitriol binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:17823"^^xsd:string) "1alpha,25-dihydroxycholecalciferol binding"^^xsd:string) AnnotationAssertion(Annotation( "Wikipedia:Calcitriol"^^xsd:string) "1,25-dihydroxyvitamin D3 binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:21872797"^^xsd:string) "1alpha,25(OH)2 vitamin D3 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:bf"^^xsd:string) "hormonally active vitamin D3 binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:17823"^^xsd:string) "1alpha,25(OH)2D3 binding"^^xsd:string) AnnotationAssertion(Annotation( "Wikipedia:Calcitriol"^^xsd:string) "1,25-dihydroxycholecalciferol binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:21872797"^^xsd:string) Annotation( "Wikipedia:Calcitriol_receptor"^^xsd:string) "Interacting selectively and non-covalently with calcitriol. Calcitriol (1,25-dihydroxycholecalciferol) is the hormonally active form of vitamin D3."^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:17823"^^xsd:string) "1alpha,25-dihydroxyvitamin D3 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "CHEBI:17933"^^xsd:string) "calcifediol binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:17933"^^xsd:string) "25(OH)D3 binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:11799400"^^xsd:string) "25OHD3 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:11799400"^^xsd:string) "Interacting selectively and non-covalently with calcidiol."^^xsd:string) AnnotationAssertion(rdfs:label "calcidiol binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:17933"^^xsd:string) "25-hydroxycholecalciferol binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:17933"^^xsd:string) "25-hydroxyvitamin D3 binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:20371703"^^xsd:string) "Interacting selectively and non-covalently with lithocholic acid."^^xsd:string) AnnotationAssertion(rdfs:label "lithocholic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:20371703"^^xsd:string) "LCA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chenodeoxycholic acid binding"^^xsd:string) AnnotationAssertion(Annotation( "CHEBI:16755"^^xsd:string) "CDCA binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:10334992"^^xsd:string) "Interacting selectively and non-covalently with chenodeoxycholic acid."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) "phosphoribosylpyrophosphate binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:4314233"^^xsd:string) "Interacting selectively and non-covalently with 5-O-phosphono-alpha-D-ribofuranosyl diphosphate."^^xsd:string) AnnotationAssertion(Annotation( "GOC:curators"^^xsd:string) "5-phosphoribose 1-diphosphate binding"^^xsd:string) AnnotationAssertion(rdfs:label "5-O-phosphono-alpha-D-ribofuranosyl diphosphate binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "IMP binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:mah"^^xsd:string) Annotation( "PMID:4314233"^^xsd:string) "Interacting selectively and non-covalently with IMP, inosine monophosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "D3 vitamins binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:bf"^^xsd:string) Annotation( "PMID:9127467"^^xsd:string) "Interacting selectively and non-covalently with D3 vitamins."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential"^^xsd:string) AnnotationAssertion(rdfs:label "voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:mtg_cardiac_conduct_nov11"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) Annotation( "PMID:8528244"^^xsd:string) "Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a ventricular cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "galactaric acid anion transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:pr"^^xsd:string) "Catalysis of the transfer of galactaric acid anion (galactarate) from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "galactarate transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "D-galactarate transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydroquinone binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:bhm"^^xsd:string) Annotation( "pmid:15667223"^^xsd:string) "Interacting selectively and non-covalently with hydroquinone."^^xsd:string) AnnotationAssertion( "quinol binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "chemoattractant activity involved in axon guidance"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "chemoattractant activity involved in axon growth cone guidance"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "chemoattractant activity involved in axon pathfinding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "chemoattractant activity involved in axon chemotaxis"^^xsd:string) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) Annotation( "PMID:21658587"^^xsd:string) "Any chemoattractant activity that is involved in axon guidance."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ceramide 1-phosphate binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:23863933"^^xsd:string) "Interacting selectively and non-covalently with ceramide 1-phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:23863933"^^xsd:string) "Enables the directed movement of ceramide 1-phosphate into, out of or within a cell, or between cells."^^xsd:string) AnnotationAssertion(rdfs:label "ceramide 1-phosphate transporter activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "ABA-GE transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:24028845"^^xsd:string) "Catalysis of the transfer of (+)-abscisic acid D-glucopyranosyl ester from one side of the membrane to the other."^^xsd:string) AnnotationAssertion(rdfs:label "(+)-abscisic acid D-glucopyranosyl ester transmembrane transporter activity"^^xsd:string) AnnotationAssertion( "abscisic acid glucosyl ester transmembrane transporter activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "riboflavin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:12083520"^^xsd:string) "Interacting selectively and non-covalently with riboflavin."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "L-cysteine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:bhm"^^xsd:string) Annotation( "PMID:12941942"^^xsd:string) "Interacting selectively and non-covalently with L-cysteine."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein binding involved in negative regulation of telomere maintenance via telomerase"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "protein binding involved in downregulation of telomere maintenance via telomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "protein binding involved in down-regulation of telomere maintenance via telomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "protein binding involved in inhibition of telomere maintenance via telomerase"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) "protein binding involved in down regulation of telomere maintenance via telomerase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:dph"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:24013504"^^xsd:string) "Any protein binding that is involved in negative regulation of telomere maintenance via telomerase."^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "sn-glycerol 3-phosphate binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:bhm"^^xsd:string) Annotation( "PMID:23013274"^^xsd:string) "Interacting selectively and non-covalently with sn-glycerol 3-phosphate."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "5'-adenylyl sulfate transmembrane transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "PMID:24296033"^^xsd:string) "Catalysis of the transfer of 5'-adenylyl sulfate from one side of the membrane to the other."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "CO2 binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:TermGenie"^^xsd:string) Annotation( "GOC:bhm"^^xsd:string) Annotation( "GO_REF:0000067"^^xsd:string) Annotation( "PMID:15491402"^^xsd:string) "Interacting selectively and non-covalently with carbon dioxide."^^xsd:string) AnnotationAssertion(rdfs:label "carbon dioxide binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:1.1.1.-"^^xsd:string) Annotation( "MetaCyc:RXN0-4281"^^xsd:string) Annotation( "PMID:16077126"^^xsd:string) Annotation( "RHEA:27989"^^xsd:string) "Catalysis of the reaction: H+ + methylglyoxal + NADPH <=> hydroxyacetone + NADP+."^^xsd:string) AnnotationAssertion(rdfs:label "methylglyoxal reductase (NADPH-dependent, acetol producing)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "IDP phosphatase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:20385596"^^xsd:string) "Catalysis of the reaction: IDP + H2O = IMP + phosphate."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:20385596"^^xsd:string) "Catalysis of the reaction: XDP + H2O = XMP + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "XDP phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:BHF"^^xsd:string) Annotation( "GOC:rl"^^xsd:string) Annotation( "PMID:16382099"^^xsd:string) Annotation( "http://en.wikipedia.org/wiki/Calcium_channel"^^xsd:string) "Catalysis of the transmembrane transfer of a calcium ion by an intermediate voltage-gated channel. An intermediate voltage-gated channel is a channel whose open state is dependent on intermediate voltage across the membrane in which it is embedded."^^xsd:string) AnnotationAssertion(rdfs:label "intermediate voltage-gated calcium channel activity"^^xsd:string) AnnotationAssertion( "R-type calcium channel"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glycerol dehydrogenase [NAD(P)+] activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:22979944"^^xsd:string) "Catalysis of an oxidation-reduction (redox) reaction in which glycerol is converted into glycerone and NAD+ or NADP is reduced."^^xsd:string) AnnotationAssertion( "glycerol dehydrogenase activity, NAD or NADP as acceptor"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.1.25.-"^^xsd:string) Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:9708997"^^xsd:string) "Catalysis of the endonucleolytic cleavage immediately 5' to pyrimidine dimers to products with 5'-phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "5' deoxyribonuclease (pyrimidine dimer) activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "phosphatidic acid transporter activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:23042293"^^xsd:string) "Enables the directed movement of phosphatidic acid into, out of or within a cell, or between cells. Phosphatidic acid refers to a glycophospholipids with, in general, a saturated fatty acid bonded to carbon-1, an unsaturated fatty acid bonded to carbon-2, and a phosphate group bonded to carbon-3."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:23316050"^^xsd:string) "Catalysis of the reaction: DNA containing 5-methylcytosine + H2O = DNA with abasic site + 5-methylcytosine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the DNA 5-methylcytosine and the deoxyribose sugar to remove the 5-methylcytosine, leaving an abasic site."^^xsd:string) AnnotationAssertion(rdfs:label "DNA-5-methylcytosine glycosylase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "MetaCyc:RXN-8990"^^xsd:string) Annotation( "PMID:16766535"^^xsd:string) Annotation( "PMID:23204519"^^xsd:string) "Catalyzes the reaction: L-phenylalanine + O2 + H2O -> phenylacetaldehyde + ammonia + hydrogen peroxide + CO2."^^xsd:string) AnnotationAssertion(rdfs:label "phenylacetaldehyde synthase activity"^^xsd:string) AnnotationAssertion( "aromatic aldehyde synthase"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "beta-phenylethylamine receptor activity"^^xsd:string) AnnotationAssertion(rdfs:label "2-phenylethylamine receptor activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:16878137"^^xsd:string) "Combining with the biogenic amine 2-phenylethylamine to initiate a change in cell activity."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:16878137"^^xsd:string) "Combining with the biogenic amine trimethylamine to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "trimethylamine receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "PMID:10077852"^^xsd:string) "Catalysis of the reaction: a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M = methyl-CoM + a [Co(I) methanol-specific corrinoid protein]."^^xsd:string) AnnotationAssertion(rdfs:label "[methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "thiazole synthase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:2.8.1.10"^^xsd:string) Annotation( "GOC:cjk"^^xsd:string) Annotation( "PMID:22031445"^^xsd:string) Annotation( "RHEA:26300"^^xsd:string) "Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + thiocarboxy-adenylate-[sulfur-carrier protein ThiS] = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS] + 2 H2O."^^xsd:string) AnnotationAssertion( "1-deoxy-D-xylulose 5-phosphate:thiol sulfurtransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:rb"^^xsd:string) Annotation( "PMID:23721653"^^xsd:string) "Stops, prevents or reduces the activity of ATP-dependent RNA helicase."^^xsd:string) AnnotationAssertion(rdfs:label "ATP-dependent RNA helicase inhibitor activity"^^xsd:string) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:23611783"^^xsd:string) "Catalysis of the reaction: a flavonoid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated flavonoid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a flavonoid acceptor, producing the sulfated flavonoid derivative."^^xsd:string) AnnotationAssertion(rdfs:label "flavonoid sulfotransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "linoleate 9-lipoxygenase activity"^^xsd:string) AnnotationAssertion( "9-lipoxygenase activity"^^xsd:string) AnnotationAssertion( "9S-lipoxygenase activity"^^xsd:string) AnnotationAssertion(Annotation( "EC:1.13.11.58"^^xsd:string) Annotation( "GOC:rph"^^xsd:string) Annotation( "RHEA:30294"^^xsd:string) "Catalysis of the reaction: linoleate + O2 = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate."^^xsd:string) AnnotationAssertion( "linoleate:oxygen 9S-oxidoreductase activity"^^xsd:string) AnnotationAssertion(rdfs:label "linoleate 9S-lipoxygenase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "PMID:19467604"^^xsd:string) "peroxygenase activity"^^xsd:string) AnnotationAssertion(rdfs:label "plant seed peroxidase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:19467604"^^xsd:string) "Catalysis of the reaction: R1H + R2OOH = R1OH + R2OH."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "talin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "PMID:23372168"^^xsd:string) "Interacting selectively and non-covalently with a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "EC:3.5.1.98"^^xsd:string) Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:23771057"^^xsd:string) "Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 4) + H2O = histone H3 L-lysine (position 4) + acetate. This reaction represents the removal of an acetyl group from lysine at position 4 of the histone H3 protein."^^xsd:string) AnnotationAssertion(rdfs:label "histone deacetylase activity (H3-K4 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:22723423"^^xsd:string) "Catalysis of the reaction: ATP + H2O = ADP + phosphate, where this reaction drives the unwinding of the DNA helix of DNA containing four-way junctions, including Holliday junctions."^^xsd:string) AnnotationAssertion( "ATP-dependent four-way junction DNA helicase activity"^^xsd:string) AnnotationAssertion( "ATP-dependent Holliday junction helicase activity"^^xsd:string) AnnotationAssertion(rdfs:label "ATP-dependent four-way junction helicase activity"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:21984210"^^xsd:string) "Interacting selectively and non-covalently with damaged DNA containing single-strand breaks (SSBs)."^^xsd:string) AnnotationAssertion( "SSB-containing DNA binding"^^xsd:string) AnnotationAssertion(rdfs:label "single-strand break-containing DNA binding"^^xsd:string) AnnotationAssertion( "single-strand break-containing damaged DNA binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:dgf"^^xsd:string) Annotation( "PMID:20802481"^^xsd:string) "Catalysis of the removal of the cap from an unmethylated 5'-end capped RNA resulting in the release of the entire cap structure (GpppN) and a 5' monophosphorylated RNA."^^xsd:string) AnnotationAssertion(rdfs:label "phosphodiesterase decapping endonuclease activity"^^xsd:string) AnnotationAssertion( "G(5')pppN pyrophosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "EH domain binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "PMID:11911876"^^xsd:string) Annotation( "PMID:21115825"^^xsd:string) "Interacting selectively and non-covalently with an EH domain of a protein. The EH stand for Eps15 homology. This was originally identified as a motif present in three copies at the NH2-termini of Eps15 and of the related molecule Eps15R."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:22431512"^^xsd:string) "Interacting selectively and non-covalently with euchromatin, a dispersed and relatively uncompacted form of chromatin."^^xsd:string) AnnotationAssertion(rdfs:label "euchromatin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:23912279"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + N-terminal L-serine in peptide = CoA + N-acetyl-L-serine-peptide."^^xsd:string) AnnotationAssertion(rdfs:label "peptide-serine-N-acetyltransferase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "peptide-glutamate-N-acetyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "PMID:23912279"^^xsd:string) "Catalysis of the reaction: acetyl-CoA + N-terminal L-glutamate in peptide = CoA + N-acetyl-L-glutamate-peptide."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "JA-Ile hydrolase"^^xsd:string) AnnotationAssertion(Annotation( "PMID:23943861"^^xsd:string) "Catalysis of the reaction: jasmonyl-Ile + H2O = jasmonic acid + L-isoleucine."^^xsd:string) AnnotationAssertion(rdfs:label "jasmonyl-Ile conjugate hydrolase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:rb"^^xsd:string) Annotation( "PMID:21349851"^^xsd:string) Annotation( "RHEA:30818"^^xsd:string) "Catalysis of the reaction: beta-nicotinamide D-ribonucleotide (NMN-) + H2O = beta-nicotinamide D-riboside (nicotinamide ribose, NmR) + phosphate."^^xsd:string) AnnotationAssertion(rdfs:label "NMN phosphatase activity"^^xsd:string) AnnotationAssertion( "beta-nicotinamide D-ribonucleotide phosphatase activity"^^xsd:string) AnnotationAssertion( "nicotinamide mononucleotide phosphatase activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone methyltransferase binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:ame"^^xsd:string) Annotation( "PMID:19486527"^^xsd:string) "Interacting selectively and non-covalently with a histone methyltransferase enzyme."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "dsDNA-specific endodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(rdfs:label "double-stranded DNA endodeoxyribonuclease activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:PG"^^xsd:string) Annotation( "PMID:22885404"^^xsd:string) "Catalysis of the hydrolysis of ester linkages within a double-stranded deoxyribonucleic acid molecule by creating internal breaks."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:ln"^^xsd:string) "Interacting selectively and non-covalently with a steroid hormone."^^xsd:string) AnnotationAssertion(rdfs:label "steroid hormone binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:pr"^^xsd:string) "Catalysis of the transfer of methionine into a cell or organelle, across a membrane."^^xsd:string) AnnotationAssertion( "methionine importing activity"^^xsd:string) AnnotationAssertion( "methionine importer"^^xsd:string) AnnotationAssertion(rdfs:label "methionine-importing activity"^^xsd:string) AnnotationAssertion( "methionine importer activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "histone threonine kinase activity (H2A-T120 specific)"^^xsd:string) AnnotationAssertion(Annotation( "PMID:24140421"^^xsd:string) "Catalysis of the transfer of a phosphate group to the threonine-120 residue of histone H2A."^^xsd:string) AnnotationAssertion(rdfs:label "histone kinase activity (H2A-T120 specific)"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "N6-methyladenosine-containing RNA binding"^^xsd:string) AnnotationAssertion(Annotation( "PMID:22575960"^^xsd:string) Annotation( "PMID:24284625"^^xsd:string) "Interacting selectively and non-covalently with an RNA molecule modified by N6-methyladenosine (m6A), a modification present at internal sites of mRNAs and some non-coding RNAs."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "keratin filament binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:krc"^^xsd:string) Annotation( "PMID:6170061"^^xsd:string) "Interacting selectively and non-covalently with a keratin filament, an intermediate filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "histone-glutamine methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "PMID:24352239"^^xsd:string) "Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-glutamine = S-adenosyl-L-homocysteine + (histone)-N5-methyl-glutamine."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:di"^^xsd:string) Annotation( "PMID:22796944"^^xsd:string) "Interacting selectively and non-covalently with phosphorylated serine residues in the C-terminal domain of RNA polymerase II."^^xsd:string) AnnotationAssertion(rdfs:label "RNA polymerase II C-terminal domain phosphoserine binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:di"^^xsd:string) "RNA Pol II C-terminal domain phosphoserine binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:hjd"^^xsd:string) Annotation( "PMID:23624077"^^xsd:string) "Combining with anti-Mullerian hormone to initiate a change in cell activity."^^xsd:string) AnnotationAssertion(rdfs:label "anti-Mullerian hormone receptor activity"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:di"^^xsd:string) Annotation( "PMID:22735702"^^xsd:string) "Interacting selectively and non-covalently with any part of a preribosome."^^xsd:string) AnnotationAssertion(rdfs:label "preribosome binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA 5'-methyltransferase activity"^^xsd:string) AnnotationAssertion(Annotation( "GOC:al"^^xsd:string) Annotation( "GOC:vw"^^xsd:string) Annotation( "PMID:22740346"^^xsd:string) "Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the 5'-gamma-phosphate in an RNA molecule."^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with xylan."^^xsd:string) AnnotationAssertion(rdfs:label "xylan binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "glucomannan binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with glucomannan."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with cellooligosaccharide."^^xsd:string) AnnotationAssertion(rdfs:label "cellooligosaccharide binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:obol"^^xsd:string) "mannoglycan binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with mannan."^^xsd:string) AnnotationAssertion(rdfs:label "mannan binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with amylopectin."^^xsd:string) AnnotationAssertion(rdfs:label "amylopectin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "pullulan binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with pullulan."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arabinoxylan binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with arabinoxylan."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:obol"^^xsd:string) "animal starch binding"^^xsd:string) AnnotationAssertion(rdfs:label "glycogen binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:obol"^^xsd:string) "liver starch binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with glycogen."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with starch."^^xsd:string) AnnotationAssertion(Annotation( "GOC:obol"^^xsd:string) "amidon binding"^^xsd:string) AnnotationAssertion(rdfs:label "starch binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:obol"^^xsd:string) "amylum binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with maltoheptaose."^^xsd:string) AnnotationAssertion(rdfs:label "maltoheptaose binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with galactomannan."^^xsd:string) AnnotationAssertion(rdfs:label "galactomannan binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with cyclodextrin."^^xsd:string) AnnotationAssertion(rdfs:label "cyclodextrin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "beta-(1,3),(1,4)-glucan binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with (1->3),(1->4)-beta-glucan."^^xsd:string) AnnotationAssertion( "(1,3),(1,4)-beta-glucan binding"^^xsd:string) AnnotationAssertion( "beta-1->3,1->4-glucan binding"^^xsd:string) AnnotationAssertion( "1->3,1->4-beta-glucan binding"^^xsd:string) AnnotationAssertion( "beta-1,3-1,4-glucan binding"^^xsd:string) AnnotationAssertion( "beta-(1->3),(1->4)-glucan binding"^^xsd:string) AnnotationAssertion(rdfs:label "(1->3),(1->4)-beta-glucan binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "1,6-beta-D-glucan binding"^^xsd:string) AnnotationAssertion( "beta-1,6-D-glucan binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with (1->6)-beta-D-glucan."^^xsd:string) AnnotationAssertion( "(1,6)-beta-D-glucan binding"^^xsd:string) AnnotationAssertion( "beta-(1,6)-D-glucan binding"^^xsd:string) AnnotationAssertion( "beta-1->6-D-glucan binding"^^xsd:string) AnnotationAssertion(rdfs:label "(1->6)-beta-D-glucan binding"^^xsd:string) AnnotationAssertion( "1->6-beta-D-glucan binding"^^xsd:string) AnnotationAssertion( "beta-(1->6)-D-glucan binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc."^^xsd:string) AnnotationAssertion(rdfs:label "beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with chitosan."^^xsd:string) AnnotationAssertion(rdfs:label "chitosan binding"^^xsd:string) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "(1->4)-beta-D-galactan binding"^^xsd:string) AnnotationAssertion( "(1,4)-beta-D-galactan binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with (1->4)-beta-D-galactan."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with inulin."^^xsd:string) AnnotationAssertion(rdfs:label "inulin binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with alpha-D-glucan."^^xsd:string) AnnotationAssertion(rdfs:label "alpha-D-glucan binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with L-arabinofuranose."^^xsd:string) AnnotationAssertion(rdfs:label "L-arabinofuranose binding"^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "arabinogalactan binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:mengo_curators"^^xsd:string) "Interacting selectively and non-covalently with arabinogalactan."^^xsd:string) SubClassOf( ) Declaration(Class()) AnnotationAssertion(Annotation( "GOC:obol"^^xsd:string) "3-(1,3-thiazol-2-yl)-1H-indole binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:obol"^^xsd:string) "Interacting selectively and non-covalently with camalexin."^^xsd:string) AnnotationAssertion(rdfs:label "camalexin binding"^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "quercitrin binding"^^xsd:string) AnnotationAssertion(Annotation( "GOC:obol"^^xsd:string) "Interacting selectively and non-covalently with quercitrin."^^xsd:string) SubClassOf( ) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "The physico-chemical process by which a molecular component function is carried out. Note that while all molecular component functions must be carried out by one or more molecular mechanisms, it is possible that a molecular mechanism may not necessarily result in a molecular component function. For example, a gene product might bind another molecule but have no functional effect on that other molecule.") AnnotationAssertion(rdfs:label "molecular mechanism"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "molecular component function"@en) AnnotationAssertion( "The function that a molecule carries out, by virtue of direct molecular interactions, as a component of larger biological systems. Molecular component functions must be carried out by a physical \"molecular mechanism\" class.") SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:seeAlso "regulation of molecular function") AnnotationAssertion(rdfs:label "specific molecular function regulator"@en) AnnotationAssertion( "A gene product that controls the molecular component function of another gene product, by modulating the functional efficiency of each target molecule.") SubClassOf( ) Declaration(Class()) AnnotationAssertion( "A gene product that controls the molecular activity of another gene product, by binding to the target molecule, and modulating the functional efficiency of each target molecule.") AnnotationAssertion(rdfs:label "specific molecular function regulator via binding"@en) AnnotationAssertion( "LEGO") SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "LEGO") AnnotationAssertion(rdfs:label "specific molecular function regulator via covalent modification"@en) AnnotationAssertion( "A gene product that controls the molecular activity of another gene product, by covalently modifying the target molecule, and modulating the functional efficiency of each target molecule.") SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "LEGO") AnnotationAssertion( "A gene product that controls the molecular activity of another gene product, by biosynthesis or release of a small molecule or ion that subsequently binds the target molecule, which in turn modulates the functional efficiency of each target molecule.") AnnotationAssertion(rdfs:label "specific molecular function regulator via small molecule intermediate"@en) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "Detects the presence of a target molecular entity. Directly interacts with the target, and responds to this interaction, e.g. by conformational change or by a change in affinity of other interactions.") AnnotationAssertion(rdfs:label "molecular sensor"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Detects the presence of a target molecule or ion. Directly binds the target, and responds to this interaction, e.g. by conformational change or by a change in affinity of other interactions.") AnnotationAssertion(rdfs:label "sensor via binding"@en) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "sensor via protein modification"@en) AnnotationAssertion( "Detects the presence of an enzymatically active protein (e.g. a protein kinase). Directly interacts with, and is covalently modified by the protein, and responds to this interaction, e.g. by conformational change or by a change in affinity of other interactions.") SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "sensor via oxidation-reduction"@en) AnnotationAssertion( "Detects the redox state of its environment (presence of \"available\" electrons). Directly transfers electrons, and responds to this interaction, e.g. by conformational change or by a change in affinity of other interactions.") SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "photon sensor"@en) AnnotationAssertion( "Detects the presence of a photon. Directly interacts with a photon, and responds to this interaction, e.g. by conformational change or by a change in affinity of other interactions.") SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "transcription activator"@en) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "transcription repressor"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "intercellular signal"@en) AnnotationAssertion(rdfs:seeAlso "receptor binding") AnnotationAssertion( "A molecule produced by one cell, that interacts with a receptor on another cell. The molecule generally diffuses from one cell to another, though some types of signal molecules (such as Notch ligands) are attached to the cell surface.") SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "ligand-specific signaling receptor activity"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "LEGO") AnnotationAssertion( "Serving to bring two or more molecules into proximity for the purpose of one operating on another. For example, a specificity factor will bind an enzyme and a specific substrate of that enzyme.") AnnotationAssertion(rdfs:label "molecular function specificity factor activity"@en) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:seeAlso "Directly binding to a specific molecular entity, and delivering it to a specific location/molecule.") AnnotationAssertion(rdfs:label "molecular carrier"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "A gene product that controls, via direct physical interaction, the molecular activity of another gene product.") AnnotationAssertion(rdfs:label "specific molecular activity regulator"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "By virtue of direct physical interaction with either a target gene product, or the gene or mRNA encoding the target, initiates a process resulting in a change in cellular abundance of the target gene product.") AnnotationAssertion(rdfs:label "specific molecular abundance regulator"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "specific macromolecular localization regulator"@en) AnnotationAssertion( "Directly binds or covalently modifies a specific target gene product to alter the localization of the target.") SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:seeAlso "regulation of transcription") AnnotationAssertion(rdfs:label "transcriptional regulator"@en) AnnotationAssertion( "Interacting selectively and non-covalently with one or more macromolecules (can be a protein and/or a DNA or RNA template), in order to modulate transcription of the template.") SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "specific protein degradation regulator"@en) AnnotationAssertion( "By virtue of direct physical interaction with a protein molecule, initiates a process resulting in a decrease in cellular abundance of the target protein molecule. An example would be a protein kinase or protein ubiquitin ligase that by covalently modifying a protein initiates protein degradation.") SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "substrate for catalytic activity"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "substrate binding"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "By virtue of direct physical interaction with an RNA molecule, initiates a process resulting in a decrease in cellular abundance of the target RNA molecule. An example would be a microRNA that by binding to an RNA initiates RNA degradation.") AnnotationAssertion(rdfs:label "specific RNA degradation regulator"@en) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion( "By virtue of directly covalently modifying (\"tagging\") a protein molecule, initiates a process resulting in degradation of the target protein molecule. An example would be a protein kinase or protein ubiquitin ligase that by covalently modifying a protein initiates protein degradation.") AnnotationAssertion(rdfs:label "protein degradation tagging activity"@en) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "transcriptional insulator activity"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Directly acts to remove or chemically alter a molecular entity that would otherwise be toxic to the cell or organism.") AnnotationAssertion(rdfs:label "molecular detoxifier"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:comment "Functioning to synthesize and/or degrade a specific small molecule. This function is accomplished by the enzymatic catalysis of a chemical reaction.") AnnotationAssertion(rdfs:label "small molecule interconversion function"@en) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "molecular energy harvesting activity"@en) AnnotationAssertion( "The use of an energy source (\"chemical potential\"), which will be coupled to another molecular function that requires energy.") SubClassOf( ) Declaration(Class()) AnnotationAssertion( "LEGOr") AnnotationAssertion( "Through direct physical interaction, modifies the structure of a DNA molecule. This modification can be to the primary structure (e.g. through nuclease activity or base-modifying enzymes), secondary structure (e.g. strand separation) or tertiary structure (e.g. DNA bending).") AnnotationAssertion(rdfs:label "DNA structure modulator"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:seeAlso "macromolecule modification") AnnotationAssertion(rdfs:label "macromolecular covalent modification activity"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein modification activity"@en) AnnotationAssertion(rdfs:seeAlso "cellular protein modification process") SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "small molecule degradation function"@en) AnnotationAssertion( "Functioning to degrade a specific small molecule. This function is accomplished by the enzymatic catalysis of a chemical reaction.") SubClassOf( ) Declaration(Class()) AnnotationAssertion( "LEGOr") AnnotationAssertion( "Through direct physical interaction, modifies the structure of an RNA molecule. This modification can be to the primary structure (e.g. through nuclease activity or base-modifying enzymes), secondary structure (e.g. strand separation) or tertiary structure (e.g. RNA folding).") AnnotationAssertion(rdfs:label "RNA structure modulator"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion( "LEGOr") AnnotationAssertion(rdfs:seeAlso "ion transport") AnnotationAssertion(rdfs:label "small molecule or ion transporter"@en) AnnotationAssertion( "Functioning to transport a small molecule or ion from one cellular location to another, by direct physical interaction with that molecule and/or with the membrane that would otherwise be a barrier.") SubClassOf( ) Declaration(Class()) AnnotationAssertion( "Interacts directly with a target protein precursor, to produce the biologically stable ('mature') form and location of the target protein.") AnnotationAssertion(rdfs:label "protein maturation factor"@en) AnnotationAssertion( "LEGOr") AnnotationAssertion(rdfs:seeAlso "protein maturation") SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein glycosylation activity"@en) SubClassOf( ) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "signal sequence-recognizing protein transport activity"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "antitermination factor"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "vesicle adaptor activity"@en) AnnotationAssertion( "Directly binds and links vesicle cargo molecules or vesicle assembly proteins to formed or budding vesicles.") SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "calcium ion sensor activity"@en) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) Declaration(Class()) AnnotationAssertion(rdfs:label "structural constituent of vesicle"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hijacked molecular function"@en) AnnotationAssertion( "A function that was not selected for in the evolution of an organism, but arises from co-option by another organism, e.g. a human protein used as a virus receptor.") SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "carrier protein transport activity"@en) AnnotationAssertion(rdfs:comment "Transports, via direct interaction, a protein molecule that is carrying a small molecule or ion.") SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "hydrolase activity, acting to interconvert small molecules"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "isomerase activity, acting to interconvert small molecules"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "kinase activity, acting to interconvert small molecules"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "ligase activity, acting to interconvert small molecules"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "lyase activity, acting to interconvert small molecules"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "transferase activity, acting to interconvert small molecules"@en) SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "xenobiotic efflux transporter activity"@en) AnnotationAssertion( "Transports, by direct physical interaction, a potentially toxic xenobiotic out of the cell.") AnnotationAssertion(rdfs:seeAlso "toxin transport") SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:seeAlso "toxin catabolic process") AnnotationAssertion(rdfs:label "xenobiotic chemical modification activity"@en) AnnotationAssertion( "Chemically modifies, through an enzymatic reaction, a xenobiotic in order to facilitate removal or catabolism.") SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "DNA modification activity"@en) AnnotationAssertion(rdfs:seeAlso "DNA modification") SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "RNA modification activity"@en) AnnotationAssertion(rdfs:seeAlso "RNA modification") SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:seeAlso "regulation of receptor internalization") AnnotationAssertion(rdfs:label "cell surface protein internalization regulator"@en) AnnotationAssertion( "By virtue of direct physical interaction with a protein, modulates the process of internalization (endocytosis) of that protein.") SubClassOf( ) Declaration(Class()) AnnotationAssertion(rdfs:label "protein biosynthesis or maturation factor"@en) AnnotationAssertion( "Molecular functions required to express the function of a protein product from an mRNA. By virtue of direct physical interactions, directly contributes to the production of a functional protein, including translation and maturation of the protein.") SubClassOf( ) Declaration(Class()) AnnotationAssertion( "A molecular component that contributes, by virtue of direct physical interactions, the translation of a polypeptide. This function includes ribosomal components as well as tRNAs and tRNA charging enzymes.") AnnotationAssertion(rdfs:label "component of basal translation machinery"@en) SubClassOf( ) Declaration(ObjectProperty()) AnnotationAssertion(rdfs:label "part_of"^^xsd:string) InverseObjectProperties( ) TransitiveObjectProperty() Declaration(ObjectProperty()) AnnotationAssertion(rdfs:label "has_part"^^xsd:string) InverseObjectProperties( ) TransitiveObjectProperty() Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) SubObjectPropertyOf( ) Declaration(ObjectProperty()) SubObjectPropertyOf( ) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) AnnotationAssertion(rdfs:label "definition") SubAnnotationPropertyOf( ) SubAnnotationPropertyOf( ) SubAnnotationPropertyOf( ) SubAnnotationPropertyOf( ) SubAnnotationPropertyOf( ) SubAnnotationPropertyOf( ) AnnotationAssertion( "goslim_lego"@en) SubAnnotationPropertyOf( ) SubAnnotationPropertyOf( ) SubAnnotationPropertyOf( ) SubAnnotationPropertyOf( ) SubAnnotationPropertyOf( ) SubAnnotationPropertyOf( ) SubAnnotationPropertyOf( ) SubAnnotationPropertyOf( ) SubAnnotationPropertyOf( ) SubAnnotationPropertyOf( ) SubAnnotationPropertyOf( ) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty(rdfs:label)) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) )