# HISTORY 26 Apr 2016: Updated by: TOUCHUP-v1.15 18 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150916: root_PTN001248125 has function metal ion transmembrane transporter activity (GO:0046873) 20150916: root_PTN001248125 has function transition metal ion binding (GO:0046914) 20150916: Bacteria _PTN002013155 has function copper ion transmembrane transporter activity (GO:0005375) 20150916: Bacteria _PTN002013155 has function copper ion binding (GO:0005507) # cellular_component 20150916: root_PTN001248125 is found in outer membrane-bounded periplasmic space (GO:0030288) # biological_process 20150916: root_PTN001248125 participates in metal ion transport (GO:0030001) 20150916: Bacteria _PTN002013155 participates in copper ion export (GO:0060003) 20150916: Bacteria _PTN002013155 participates in cellular copper ion homeostasis (GO:0006878) 20150916: Bacteria _PTN002013155 participates in plasma membrane copper ion transport (GO:0015679) 20150916: Bacteria _PTN002013155 participates in detoxification of copper ion (GO:0010273) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).