# HISTORY 27 Mar 2016: Updated by: TOUCHUP-v1.15 18 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20141114: Opisthokonta_PTN001210741 has function steroid hydroxylase activity (GO:0008395) 20141114: Euteleostomi_PTN000670379 has function arachidonic acid epoxygenase activity (GO:0008392) 20141114: Euteleostomi_PTN000670523 has function arachidonic acid epoxygenase activity (GO:0008392) # cellular_component # biological_process 20141114: Euteleostomi_PTN000670379 participates in arachidonic acid metabolic process (GO:0019369) 20141114: Euteleostomi_PTN000670523 participates in epoxygenase P450 pathway (GO:0019373) 20141114: Theria _PTN000670816 participates in naphthalene metabolic process (GO:0018931) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).