# HISTORY 11 Aug 2016: Saved by pascalegaudet using Paint 2.22 # molecular_function 20160811: node_PTN001921855 has function substrate-specific transmembrane transporter activity (GO:0022891) # cellular_component 20160811: root_PTN001921833 is found in integral component of membrane (GO:0016021) 20160811: Metazoa_PTN001921838 is found in synaptic vesicle (GO:0008021) 20160811: node_PTN001921855 is found in plasma membrane (GO:0005886) 20160811: Metazoa_PTN001921838 is found in neuron projection (GO:0043005) 20160811: Metazoa_PTN001921838 is found in synaptic vesicle membrane (GO:0030672) # biological_process 20160811: Metazoa_PTN001921838 participates in neurotransmitter uptake (GO:0001504) 20160811: node_PTN001921855 participates in organic hydroxy compound transport (GO:0015850) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).