# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 17 Mar 2016: Updated by: TOUCHUP-v1.14 27 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150916: root_PTN001510949 has function immunoglobulin receptor binding (GO:0034987) 20150916: root_PTN001510949 has function antigen binding (GO:0003823) # cellular_component 20150916: root_PTN001510949 is found in blood microparticle (GO:0072562) 20150916: root_PTN001510949 is found in external side of plasma membrane (GO:0009897) 20150916: root_PTN001510949 is found in immunoglobulin complex, circulating (GO:0042571) # biological_process 20150916: root_PTN001510949 participates in B cell receptor signaling pathway (GO:0050853) 20150916: root_PTN001510949 participates in innate immune response (GO:0045087) 20150916: root_PTN001510949 participates in complement activation, classical pathway (GO:0006958) 20150916: root_PTN001510949 participates in defense response to bacterium (GO:0042742) 20150916: root_PTN001510949 participates in phagocytosis, recognition (GO:0006910) 20150916: root_PTN001510949 participates in phagocytosis, engulfment (GO:0006911) 20150916: root_PTN001510949 participates in positive regulation of B cell activation (GO:0050871) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).