# HISTORY 26 Mar 2016: Updated by: TOUCHUP-v1.15 17 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150918: root_PTN001470437 has function metal ion transmembrane transporter activity (GO:0046873) 20150918: Dikarya_PTN001089447 has function magnesium ion transmembrane transporter activity (GO:0015095) 20150918: Proteobacteria_PTN000488805 has function nickel cation transmembrane transporter activity (GO:0015099) 20150918: Proteobacteria_PTN000488805 has function magnesium ion transmembrane transporter activity (GO:0015095) 20150918: Proteobacteria_PTN000488805 has function cobalt ion transmembrane transporter activity (GO:0015087) # cellular_component 20150918: root_PTN001470437 is found in membrane (GO:0016020) 20150918: Dikarya_PTN001852893 is found in vacuole-mitochondrion membrane contact site (GO:1990816) 20150918: Bacteria _PTN000488811 is found in integral component of plasma membrane (GO:0005887) # biological_process 20150918: root_PTN001470437 participates in cation transmembrane transport (GO:0098655) 20150918: Dikarya_PTN001089447 participates in magnesium ion transport (GO:0015693) 20150918: Proteobacteria_PTN000488805 participates in nickel cation transmembrane transport (GO:0035444) 20150918: Proteobacteria_PTN000488805 participates in cobalt ion transport (GO:0006824) 20150918: Proteobacteria_PTN000488805 participates in magnesium ion transport (GO:0015693) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).