# HISTORY
25 Mar 2016: Updated by: TOUCHUP-v1.15
15 Mar 2016: Updated by: TOUCHUP-v1.14

# molecular_function
20140815: Opisthokonta_PTN000289470 has function RNA polymerase II core promoter proximal region sequence-specific DNA binding (GO:0000978) 
20140815: Opisthokonta_PTN000289470 has function transcription factor activity, sequence-specific DNA binding (GO:0003700) 

# cellular_component
20140815: Opisthokonta_PTN000289470 is found in nucleus (GO:0005634) 

# biological_process
20140815: Opisthokonta_PTN000289470 participates in regulation of transcription from RNA polymerase II promoter (GO:0006357) 
20140815: Chordata_PTN000973196 participates in negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning (GO:0021914) 
20140815: Chordata_PTN000973196 participates in cilium assembly (GO:0042384) 
20140815: Euteleostomi_PTN000289504 participates in endocrine pancreas development (GO:0031018) 
20140815: Theria <Mammalia>_PTN000289506 participates in regulation of insulin secretion (GO:0050796) 
20140815: Theria <Mammalia>_PTN000289506 participates in pancreatic D cell differentiation (GO:0003311) 
20140815: Theria <Mammalia>_PTN000289506 participates in type B pancreatic cell differentiation (GO:0003309) 
20140815: Theria <Mammalia>_PTN000289506 participates in pancreatic epsilon cell differentiation (GO:0090104) 
20140815: Theria <Mammalia>_PTN000289506 participates in pancreatic A cell differentiation (GO:0003310) 
20140815: Mammalia_PTN000289537 participates in immune response (GO:0006955) 
20140815: Mammalia_PTN000289588 participates in type B pancreatic cell differentiation (GO:0003309) 
20140815: Mammalia_PTN000289588 participates in cilium assembly (GO:0042384) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).