# HISTORY 04 Aug 2016: Updated by: TOUCHUP-v1.21 20 Apr 2016: Saved by pascalegaudet using Paint 2.0-beta15 # molecular_function 20160420: Bilateria_PTN000275807 has function transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding (GO:0001077) # cellular_component 20160420: Bilateria_PTN000275807 is found in nucleus (GO:0005634) # biological_process 20160420: Bilateria_PTN000275807 participates in gliogenesis (GO:0042063) 20160420: Deuterostomia_PTN000275808 participates in calcium ion homeostasis (GO:0055074) 20160420: Theria _PTN000275814 participates in cell differentiation involved in embryonic placenta development (GO:0060706) 20160420: node_PTN000964769 does NOT participate in gliogenesis (GO:0042063) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).