# HISTORY 25 Mar 2016: Updated by: TOUCHUP-v1.15 15 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20140730: root_PTN000225632 has function flavin adenine dinucleotide binding (GO:0050660) 20140730: root_PTN000225632 has function xanthine dehydrogenase activity (GO:0004854) 20140730: root_PTN000225632 has function oxidoreductase activity, acting on the aldehyde or oxo group of donors (GO:0016903) 20140730: Embryophyta_PTN000935795 has LOST/MODIFIED function xanthine dehydrogenase activity (GO:0004854) # cellular_component 20140730: root_PTN000225632 is found in cytosol (GO:0005829) 20140730: Theria _PTN000225699 is found in extracellular space (GO:0005615) # biological_process 20140730: root_PTN000225632 participates in xanthine catabolic process (GO:0009115) 20140730: Embryophyta_PTN000935795 does NOT participate in xanthine catabolic process (GO:0009115) # PRUNED 25 Mar 2016: node_PTN000935815 has been pruned from tree # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES 15 Mar 2016: node_PTN000935815 has been pruned from tree # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).