# HISTORY
24 Mar 2016: Updated by: TOUCHUP-v1.15
14 Mar 2016: Updated by: TOUCHUP-v1.12

# molecular_function
20110121: Magnoliophyta_PTN000072135 has function long-chain-alcohol oxidase activity (GO:0046577) 

# cellular_component

# biological_process

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED

# NOTES
Fast-pass curation of PTHR10668 (PHYTOENE DEHYDROGENASE) family
General information:
- Animal origin, the major form of vitamin A is an ester, which is converted to the retinol.
- Carotenoids are tetraterpenoid organic pigments that are naturally occurring in the chloroplasts and chromoplasts of plants and some other photosynthetic organisms like algae, some types of fungus some bacteria and at least one species of aphid. Carotenoids are generally not manufactured by species in the animal kingdom
MF:
- Propagate GO:0051786 all-trans-retinol 13,14-reductase activity to AN10
- Propagate GO:0046608 carotenoid isomerase activity to AN54
- Propagate GO:0046577 long-chain-alcohol oxidase activity to AN83
CC
- Propagate GO:0005789 endoplasmic reticulum membrane to AN10
- Propagate GO:0009507 chloroplast to AN54
- Propagate GO:0005792 microsome to AN83
- Propagate GO: 0005813 centrosome to AN105
- Propagate GO:0005634 nucleus to AN105
- Propagate GO:0031083 BLOC-1 complex to AN105
- According to PMID:15358783, MGI need to delete nuclear membrane and nuclear outer membrane annotation, could add a microsome annotaton.
- According to PMID: 15102850 MGI need to add annotation GO:0031083 BLOC-1 complex.
- No propagation of HTP data at the moment.
PMID:16618929 TAIR AT4G28570 The false positive rate of localization of proteins using the LOPIT approach could be estimated at �10%
TAIR AT5G49555 mitochondrion
BP
- Propagate GO:0042572 retinol metabolic process to AN10
- Propagate GO:0016117 carotenoid biosynthetic process to AN54
- Propagate GO:0045944 positive regulation of transcription from RNA polymerase II promoter to AN105
LN, 20 Jan 2011

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).