# HISTORY 27 Oct 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20161027: root_PTN000826174 has function DNA binding (GO:0003677) 20161027: root_PTN000826174 has function histone binding (GO:0042393) 20161027: Eukaryota_PTN002235452 has LOST/MODIFIED function DNA binding (GO:0003677) 20161027: Eukaryota_PTN002235452 has LOST/MODIFIED function histone binding (GO:0042393) # cellular_component 20161027: root_PTN000826174 is found in nuclear nucleosome (GO:0000788) 20161027: Eukaryota_PTN001289503 is found in chromosome, centromeric region (GO:0000775) 20161027: Eukaryota_PTN001289503 is found in kinetochore (GO:0000776) 20161027: Eukaryota_PTN002235452 is NOT found in nuclear nucleosome (GO:0000788) 20161027: Eukaryota_PTN002235452 is found in nucleus (GO:0005634) # biological_process 20161027: Eukaryota_PTN001289503 participates in protein localization to kinetochore involved in kinetochore assembly (GO:1903394) 20161027: Eukaryota_PTN000049975 participates in nucleosome assembly (GO:0006334) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).