Gene Ontology Definition Changes
Files used:
- file 1 (old): 24:11:2011 22:03, cvs revision 1.2403
- file 2 (new): 02:12:2011 16:46, cvs revision 1.2418
- Database: unknown DB type, unknown DB release name
Terms with changed definitions
GO:0002752 : cell surface pattern recognition receptor signaling pathway
OLD: Any series of molecular signals generated as a consequence of binding to a cell surface pattern recognition receptor (PRR). Such receptors bind for molecular patterns based on a repeating or polymeric structures, like those of polysaccharides or peptidoglycans, which are sometimes associated with potential pathogens.
NEW: Any series of molecular signals generated as a consequence of binding to a cell surface pattern recognition receptor (PRR). Such receptors bind molecular patterns based on a repeating or polymeric structures, like those of polysaccharides or peptidoglycans, which are sometimes associated with potential pathogens.
GO:0002753 : cytoplasmic pattern recognition receptor signaling pathway
OLD: Any series of molecular signals generated as a consequence of binding to a pattern recognition receptor (PRR) located in the cytoplasm. Such receptors bind for molecular patterns based on a repeating or polymeric structures, like those of polysaccharides or peptidoglycans, which are sometimes associated with potential pathogens.
NEW: Any series of molecular signals generated as a consequence of binding to a pattern recognition receptor (PRR) located in the cytoplasm. Such receptors bind molecular patterns based on a repeating or polymeric structures, like those of polysaccharides or peptidoglycans, which are sometimes associated with potential pathogens.
0 annotations
GO:0002754 : intracellular vesicle pattern recognition receptor signaling pathway
OLD: Any series of molecular signals generated as a consequence of binding to a pattern recognition receptor (PRR) located within the membrane of an intracellular vesicle such as an endosome or lysosome. Such receptors bind for molecular patterns based on a repeating or polymeric structures, like those of polysaccharides or peptidoglycans, which are sometimes associated with potential pathogens.
NEW: Any series of molecular signals generated as a consequence of binding to a pattern recognition receptor (PRR) located within the membrane of an intracellular vesicle such as an endosome or lysosome. Such receptors bind molecular patterns based on a repeating or polymeric structures, like those of polysaccharides or peptidoglycans, which are sometimes associated with potential pathogens.
GO:0003707 : steroid hormone receptor activity
OLD: Combining with a steroid hormone to initiate a change in cell activity.
NEW: Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
GO:0003708 : retinoic acid receptor activity
OLD: Combining with retinoic acid to initiate a change in cell activity. Retinoic acid is one of the forms of vitamin A.
NEW: Combining with retinoic acid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA\npolymerase II. Retinoic acid is one of the forms of vitamin A.
GO:0004879 : ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
(was ligand-dependent nuclear receptor activity)
OLD: A ligand-dependent receptor found in the nucleus of the cell.
NEW: Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
0 annotations
GO:0004880 : juvenile hormone receptor activity
OLD: Combining with juvenile hormone to initiate a change in cell activity.
NEW: Combining with juvenile hormone and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
GO:0004882 : androgen receptor activity
OLD: Combining with an androgen to initiate a change in cell activity.
NEW: Combining with an androgen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
GO:0004883 : glucocorticoid receptor activity
OLD: Combining with a glucocorticoid to initiate a change in cell activity.
NEW: Combining with a glucocorticoid and transmitting the signal within the cell trigger a change in cell activity or function.
GO:0004884 : ecdysteroid hormone receptor activity
OLD: Combining with ecdysteroid hormone to initiate a change in cell activity.
NEW: Combining with an ecdysteroid hormone and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
GO:0004886 : 9-cis retinoic acid receptor activity
(was retinoid-X receptor activity)
OLD: Combining with 9-cis retinoic acid to initiate a change in cell activity.
NEW: Combining with 9-cis retinoic acid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
GO:0004887 : thyroid hormone receptor activity
OLD: Combining with thyroid hormone to initiate a change in cell activity.
NEW: Combining with thyroid hormone and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
GO:0008301 : DNA binding, bending
(was DNA bending activity)
OLD: An activity that results in binding to DNA and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
NEW: The activity of binding to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
GO:0017082 : mineralocorticoid receptor activity
OLD: Combining with mineralocorticoid to initiate a change in cell activity.
NEW: Combining with a mineralocorticoid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
GO:0030284 : estrogen receptor activity
OLD: Combining with estrogen to initiate a change in cell activity.
NEW: Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function.
GO:0030487 : inositol-4,5-bisphosphate 5-phosphatase activity
OLD: Catalysis of the removal of a phosphate group from the carbon-5 position of D-myo-inositol 4,5-bisphosphate.
NEW: Catalysis of the reaction: 1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate.
GO:0030518 : intracellular steroid hormone receptor signaling pathway
(was steroid hormone receptor signaling pathway)
OLD: Any series of molecular signals generated as a consequence of a steroid hormone receptor binding to one of its physiological ligands.
NEW: A series of molecular signals generated as a consequence of a intracellular steroid hormone receptor binding to one of its physiological ligands.
GO:0030520 : intracellular estrogen receptor signaling pathway
(was estrogen receptor signaling pathway)
OLD: Any series of molecular signals generated as a consequence of an estrogen binding to its receptor.
NEW: Any series of molecular signals generated as a consequence of an intracellular estrogen receptor binding to one of its physiological ligands. The pathway begins with receptor-ligand binding, and ends with regulation of a downstream cellular process (e.g. transcription).
0 annotations
GO:0031963 : cortisol receptor activity
OLD: Combining with cortisol to initiate a change in cell activity.
NEW: Combining with cortisol and transmitting the signal within the cell to trigger a change in cell activity or function.
GO:0033143 : regulation of intracellular steroid hormone receptor signaling pathway
(was regulation of steroid hormone receptor signaling pathway)
OLD: Any process that modulates the frequency, rate or extent of the activity of any steroid hormone receptor signaling pathway.
NEW: Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
GO:0033144 : negative regulation of intracellular steroid hormone receptor signaling pathway
(was negative regulation of steroid hormone receptor signaling pathway)
OLD: Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any steroid hormone receptor signaling pathway.
NEW: Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
GO:0033145 : positive regulation of intracellular steroid hormone receptor signaling pathway
(was positive regulation of steroid hormone receptor signaling pathway)
OLD: Any process that activates or increases the frequency, rate or extent of the activity of any steroid hormone receptor signaling pathway.
NEW: Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
GO:0033146 : regulation of intracellular estrogen receptor signaling pathway
(was regulation of estrogen receptor signaling pathway)
OLD: Any process that modulates the frequency, rate or extent of the activity of an estrogen receptor signaling pathway.
NEW: Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
GO:0033147 : negative regulation of intracellular estrogen receptor signaling pathway
(was negative regulation of estrogen receptor signaling pathway)
OLD: Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an estrogen receptor signaling pathway.
NEW: Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
GO:0033148 : positive regulation of intracellular estrogen receptor signaling pathway
(was positive regulation of estrogen receptor signaling pathway)
OLD: Any process that activates or increases the frequency, rate or extent of the activity of an estrogen receptor signaling pathway.
NEW: Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
GO:0035964 : COPI-coated vesicle budding
OLD: The evagination of a Golgi membrane, resulting in formation of a COPI vesicle.
NEW: The evagination of a Golgi membrane, resulting in formation of a COPI-coated vesicle.
GO:0090114 : COPII-coated vesicle budding
OLD: The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII vesicle.
NEW: The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle.