Gene Ontology: Ontology Comparison Report
Files used:
- file 1 (old): go-2011-10-15.obo; date: 14:10:2011 16:31; CVS revision: 1.2327
- file 2 (new): go-2011-10-22.obo; date: 21:10:2011 10:06; CVS revision: 1.2341
New terms
Obsoletions
ID | name | namespace |
---|---|---|
GO:0035110 | leg morphogenesis
Consider: GO:0007480, GO:0035108, GO:0035137 This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying. |
biological_process |
GO:0035111 | leg joint morphogenesis
Consider: GO:0016348, GO:0036023 This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying. |
biological_process |
GO:0035286 | leg segmentation
Consider: GO:0035285, GO:0036011 This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying. |
biological_process |
GO:0046590 | embryonic leg morphogenesis
Consider: GO:0030326, GO:0035116 This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying. |
biological_process |
GO:0046591 | embryonic leg joint morphogenesis
Consider: GO:0036023 This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying. |
biological_process |
Term merges
Old ID | Old name | Merged into | Merged term name |
---|---|---|---|
GO:0004981 | muscarinic acetylcholine receptor activity | GO:0016907 | G-protein coupled acetylcholine receptor activity |
GO:0031790 | M1 muscarinic acetylcholine receptor binding | GO:0031789 | G-protein coupled acetylcholine receptor binding |
GO:0031791 | M2 muscarinic acetylcholine receptor binding | GO:0031789 | G-protein coupled acetylcholine receptor binding |
GO:0031792 | M3 muscarinic acetylcholine receptor binding | GO:0031789 | G-protein coupled acetylcholine receptor binding |
GO:0031793 | M4 muscarinic acetylcholine receptor binding | GO:0031789 | G-protein coupled acetylcholine receptor binding |
GO:0031794 | M5 muscarinic acetylcholine receptor binding | GO:0031789 | G-protein coupled acetylcholine receptor binding |
Term changes
File 1 (14:10:2011 16:31, 1.2327) | File 2 (21:10:2011 10:06, 1.2341) |
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GO:0000988 : protein binding transcription factor activity | |
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relationship |
relationship part_of GO:2001141 |
GO:0001608 : G-protein coupled nucleotide receptor activity | |
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name def |
name G-protein coupled nucleotide receptor activity def Combining with a nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. synonym "nucleotide receptor activity, G-protein coupled" EXACT [GOC:bf] |
GO:0001609 : G-protein coupled adenosine receptor activity | |
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name def |
name G-protein coupled adenosine receptor activity def Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. synonym "adenosine receptor activity, G-protein coupled" EXACT [GOC:bf] |
GO:0001637 : G-protein coupled chemoattractant receptor activity | |
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name def synonym |
name G-protein coupled chemoattractant receptor activity def Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. synonym "G-protein chemoattractant receptor activity" EXACT [GOC:bf] |
GO:0001640 : adenylate cyclase inhibiting metabotropic glutamate receptor activity | |
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def |
def Combining with glutamate and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex to inhibit downstream adenylate cyclase activity. |
GO:0001647 : G-protein coupled cytokinin receptor activity | |
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def |
def Combining with cytokinin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. synonym "cytokinin receptor activity, G-protein coupled" EXACT [GOC:bf] |
GO:0001664 : G-protein coupled receptor binding | |
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name def |
name G-protein coupled receptor binding def Interacting selectively and non-covalently with a G-protein coupled receptor. synonym "G-protein-coupled receptor binding" EXACT [GOC:bf] |
GO:0004889 : acetylcholine-activated cation-selective channel activity | |
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name def |
name acetylcholine-activated cation-selective channel activity def Catalysis of the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine. synonym "nicotinic acetylcholine-activated cation-selective channel activity" EXACT [GOC:bf] |
GO:0004930 : G-protein coupled receptor activity | |
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def |
def Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. synonym "receptor activity, G-protein coupled" EXACT [GOC:bf] xref Wikipedia:GPCR |
GO:0004935 : adrenergic receptor activity | |
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def |
def Combining with epinephrine or norepinephrine and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex. |
GO:0005892 : acetylcholine-gated channel complex | |
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name def |
name acetylcholine-gated channel complex def A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding. synonym "nicotinic acetylcholine-gated receptor-channel complex" EXACT [GOC:bf] |
GO:0006355 : regulation of transcription, DNA-dependent | |
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is_a |
is_a GO:2001141 |
GO:0007186 : G-protein coupled receptor signaling pathway | |
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name def |
name G-protein coupled receptor signaling pathway def Any series of molecular signals initiated by an extracellular signal combining with a receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription. synonym "G-protein coupled receptor protein signaling pathway" EXACT [GOC:bf] |
GO:0007197 : inhibition of adenylate cyclase activity by G-protein coupled acetylcholine receptor signaling pathway | |
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name def |
name inhibition of adenylate cyclase activity by G-protein coupled acetylcholine receptor signaling pathway def The series of molecular signals generated as a consequence of a G-protein coupled acetylcholine receptor binding to its physiological ligand, followed by inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP. synonym "inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signaling pathway" EXACT [GOC:bf] |
GO:0007207 : activation of phospholipase C activity by G-protein coupled acetylcholine receptor signaling pathway | |
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name def |
name activation of phospholipase C activity by G-protein coupled acetylcholine receptor signaling pathway def The series of molecular signals generated as a consequence of a G-protein coupled acetylcholine receptor binding to its physiological ligand, followed by the activation of phospholipase C and the subsequent release of inositol trisphosphate. synonym "activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway" EXACT [GOC:bf] |
GO:0007213 : G-protein coupled acetylcholine receptor signaling pathway | |
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name def |
name G-protein coupled acetylcholine receptor signaling pathway def Any series of molecular signals initiated by an acetylcholine receptor on the surface of the target cell binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription. synonym "muscarinic acetylcholine receptor signaling pathway" EXACT [GOC:bf] |
GO:0007480 : imaginal disc-derived leg morphogenesis | |
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is_a |
GO:0008020 : G-protein coupled photoreceptor activity | |
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def |
def Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. synonym "photoreceptor activity, G-protein coupled" EXACT [GOC:bf] |
GO:0008227 : G-protein coupled amine receptor activity | |
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def |
def Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. synonym "amine receptor activity, G-protein coupled " EXACT [GOC:bf] |
GO:0008528 : G-protein coupled peptide receptor activity | |
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name def synonym |
name G-protein coupled peptide receptor activity def Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. synonym "peptide receptor activity, G-protein coupled" EXACT [GOC:bf] |
GO:0016348 : imaginal disc-derived leg joint morphogenesis | |
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is_a |
is_a GO:0036022 |
GO:0016492 : G-protein coupled neurotensin receptor activity | |
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name synonym |
name G-protein coupled neurotensin receptor activity synonym "neurotensin receptor activity, G-protein coupled" EXACT [GOC:bf] |
GO:0016907 : G-protein coupled acetylcholine receptor activity | |
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def |
alt_id GO:0004981 def Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. synonym "acetylcholine receptor activity, G-protein coupled" EXACT [GOC:bf] "muscarinic acetylcholine receptor activity" EXACT [] relationship part_of GO:0007213 |
GO:0031789 : G-protein coupled acetylcholine receptor binding | |
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name def |
name G-protein coupled acetylcholine receptor binding alt_id GO:0031790 GO:0031791 GO:0031792 GO:0031793 GO:0031794 def Interacting selectively and non-covalently with a G-protein coupled acetylcholine receptor. synonym "M1 muscarinic acetylcholine receptor binding" NARROW [] "M1 muscarinic acetylcholine receptor ligand" NARROW [] "M2 muscarinic acetylcholine receptor binding" NARROW [] "M2 muscarinic acetylcholine receptor ligand" NARROW [] "M3 muscarinic acetylcholine receptor binding" NARROW [] "M3 muscarinic acetylcholine receptor ligand" NARROW [] "M4 muscarinic acetylcholine receptor binding" NARROW [] "M4 muscarinic acetylcholine receptor ligand" NARROW [] "M5 muscarinic acetylcholine receptor binding" NARROW [] "M5 muscarinic acetylcholine receptor ligand" NARROW [] "muscarinic acetylcholine receptor binding" EXACT [GOC:bf] |
GO:0033282 : protein C inhibitor-acrosin complex | |
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def synonym is_a |
def A heterodimeric protein complex of protein C inhibitor (SERPINA5) and acrosin; formation of the complex inhibits the protease activity of acrosin. synonym "PCI-ACR complex" EXACT [PR:000003652, PR:000014685] "PCI-acrosin complex" EXACT [PR:000014685] "plasma serine protease inhibitor-acrosin complex" EXACT [PR:000014685] "serpin A5-acrosin complex" EXACT [PR:000014685] "SERPINA5-acrosin complex" EXACT [PR:000014685] is_a GO:0097180 |
GO:0035110 : leg morphogenesis | |
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def is_a |
def OBSOLETE. The process in which the anatomical structures of a leg are generated and organized. A leg is a limb on which an animal walks and stands. comment This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying. is_obsolete true consider GO:0007480 GO:0035108 GO:0035137 |
GO:0035111 : leg joint morphogenesis | |
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def is_a relationship |
def OBSOLETE. The process in which the anatomical structures of a leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. One example is the knee, which separates the leg tibia and femur. comment This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying. is_obsolete true consider GO:0016348 GO:0036023 |
GO:0035286 : leg segmentation | |
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def is_a relationship |
def OBSOLETE. Division of a leg into a series of semi-repetitive parts or segments. Most arthropod appendages are visibly segmented; the Drosophila leg for example has nine segments, each separated from the next by a flexible joint. comment This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying. is_obsolete true consider GO:0035285 GO:0036011 |
GO:0035775 : pronephric glomerulus morphogenesis | |
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GO:0035776 : pronephric proximal tubule development | |
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GO:0035777 : pronephric distal tubule development | |
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GO:0035778 : pronephric nephron tubule epithelial cell differentiation | |
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GO:0035787 : cell migration involved in kidney development | |
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GO:0035788 : cell migration involved in metanephros development | |
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GO:0035789 : metanephric mesenchymal cell migration | |
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GO:0035793 : positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway | |
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GO:0035799 : ureter maturation | |
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GO:0035849 : nephric duct elongation | |
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GO:0035850 : epithelial cell differentiation involved in kidney development | |
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GO:0036011 : imaginal disc-derived leg segmentation | |
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is_a |
is_a GO:0035285 |
GO:0038022 : G-protein coupled olfactory receptor activity | |
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name def synonym |
name G-protein coupled olfactory receptor activity def Combining with an odorant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. synonym "olfactory receptor activity, G-protein coupled" EXACT [GOC:bf] |
GO:0045028 : G-protein coupled purinergic nucleotide receptor activity | |
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name def synonym |
name G-protein coupled purinergic nucleotide receptor activity def Combining with a purine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. synonym "purinergic nucleotide receptor activity, G-protein coupled" EXACT [GOC:bf] |
GO:0045125 : bioactive lipid receptor activity | |
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def |
def Combining with a bioactive lipid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. A bioactive lipid is a lipid for which changes in lipid levels result in functional consequences in a variety of cellular processes. |
GO:0046590 : embryonic leg morphogenesis | |
---|---|
def is_a |
def OBSOLETE. The process, occurring in the embryo, by which the anatomical structures of the leg are generated and organized. A leg is a limb on which an animal walks and stands. comment This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying. is_obsolete true consider GO:0030326 GO:0035116 |
GO:0046591 : embryonic leg joint morphogenesis | |
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def is_a relationship |
def OBSOLETE. The process, occurring in the embryo, by which the anatomical structures of the leg joint are generated and organized. A leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. comment This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying. is_obsolete true consider GO:0036023 |
GO:0046782 : regulation of viral transcription | |
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is_a |
is_a GO:2001141 |
GO:0071340 : skeletal muscle acetylcholine-gated channel clustering | |
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name def is_a |
name skeletal muscle acetylcholine-gated channel clustering def The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals. synonym "skeletal muscle nicotinic acetylcholine receptor clustering" EXACT [GOC:bf] relationship part_of GO:0001941 |
GO:0071553 : G-protein coupled pyrimidinergic nucleotide receptor activity | |
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name def synonym |
name G-protein coupled pyrimidinergic nucleotide receptor activity def Combining with a pyrimidine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. synonym "pyrimidinergic nucleotide receptor activity, G-protein coupled" EXACT [GOC:bf] |
GO:2000004 : regulation of metanephric S-shaped body morphogenesis | |
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GO:2000005 : negative regulation of metanephric S-shaped body morphogenesis | |
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GO:2000006 : regulation of metanephric comma-shaped body morphogenesis | |
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GO:2000007 : negative regulation of metanephric comma-shaped body morphogenesis | |
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GO:2000061 : regulation of ureter smooth muscle cell differentiation | |
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GO:2000062 : negative regulation of ureter smooth muscle cell differentiation | |
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GO:2000063 : positive regulation of ureter smooth muscle cell differentiation | |
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GO:2000591 : positive regulation of metanephric mesenchymal cell migration | |
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GO:2000696 : regulation of epithelial cell differentiation involved in kidney development | |
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GO:2000697 : negative regulation of epithelial cell differentiation involved in kidney development | |
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GO:2000698 : positive regulation of epithelial cell differentiation involved in kidney development | |
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GO:2000699 : fibroblast growth factor receptor signaling pathway involved in ureteric bud formation | |
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GO:2000701 : glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation | |
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GO:2000702 : regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation | |
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GO:2000703 : negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation | |
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GO:2000704 : positive regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation | |
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GO:2000730 : regulation of termination of RNA polymerase I transcription | |
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is_a |
GO:2000804 : regulation of termination of RNA polymerase II transcription, poly(A)-coupled | |
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is_a |
GO:2001012 : mesenchymal cell differentiation involved in renal system development | |
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File Stats
Ontology | Old file | New file | Change |
---|---|---|---|
molecular function |
9141 9141 (100.0%) defined |
9138 9138 (100.0%) defined |
-3 |
cellular component |
2906 2906 (100.0%) defined |
2918 2918 (100.0%) defined |
+12 |
biological process |
21504 21504 (100.0%) defined |
21506 21506 (100.0%) defined |
+2 |
Obsolete | 1587 (4.5% of total) |
1592 (4.5% of total) |
+5 (+0.3%) |
Totals |
33551 33551 (100.0%) defined 35138 inc. obsoletes |
33562 33562 (100.0%) defined 35154 inc. obsoletes |
+16 (0.0%) |