Gene Ontology Ontology Comparison Report ========================== Files used: - file 1 (old): go-2011-08-13.obo; date: 12:08:2011 16:34; CVS revision: 1.2181 - file 2 (new): go-2011-08-20.obo; date: 19:08:2011 16:54; CVS revision: 1.2200 NEW TERMS ========= ID name namespace GO:0001179 RNA polymerase I transcription factor binding molecular_function GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript biological_process GO:0001181 core RNA polymerase I binding transcription factor activity molecular_function GO:0001182 promoter clearance from RNA polymerase I promoter biological_process GO:0001183 transcription elongation from RNA polymerase I promoter for nuclear large rRNA transcript biological_process GO:0001184 promoter clearance from RNA polymerase I promoter for nuclear large rRNA transcript biological_process GO:0001185 termination of RNA polymerase I transcription from promoter for nuclear large rRNA transcript biological_process GO:0035974 meiotic spindle pole body cellular_component GO:0035975 carbamoyl phosphate catabolic process biological_process GO:0035976 AP1 complex cellular_component GO:0035977 protein deglycosylation involved in glycoprotein catabolic process biological_process GO:0052719 apurinic/apyrimidinic endoribonuclease activity molecular_function GO:0052720 apurinic/apyrimidinic endodeoxyribonuclease activity molecular_function GO:0052721 regulation of apurinic/apyrimidinic endodeoxyribonuclease activity biological_process GO:0052722 fatty acid in-chain hydroxylase activity molecular_function GO:0052723 inositol hexakisphosphate 1-kinase activity molecular_function GO:0052724 inositol hexakisphosphate 3-kinase activity molecular_function GO:0052725 inositol-1,3,4-trisphosphate 6-kinase activity molecular_function GO:0052726 inositol-1,3,4-trisphosphate 5-kinase activity molecular_function GO:0052727 capsanthin synthase activity molecular_function GO:0052728 capsorubin synthase activity molecular_function GO:0052729 dimethylglycine N-methyltransferase activity molecular_function GO:0052730 sarcosine N-methyltransferase activity molecular_function GO:0052731 phosphocholine phosphatase activity molecular_function GO:0052732 phosphoethanolamine phosphatase activity molecular_function GO:0052733 quinate 3-dehydrogenase (NADP+) activity molecular_function GO:0052734 shikimate 3-dehydrogenase (NAD+) activity molecular_function GO:0052735 tRNA (cytosine-3-)-methyltransferase activity molecular_function GO:0052736 beta-glucanase activity molecular_function GO:0072690 vegetative growth of a single-celled organism biological_process GO:0072691 initiation of premeiotic DNA replication biological_process GO:0080186 developmental vegetative growth biological_process GO:2001013 epithelial cell proliferation involve in renal tubule morphogenesis biological_process GO:2001017 regulation of retrograde axon cargo transport biological_process GO:2001018 negative regulation of retrograde axon cargo transport biological_process GO:2001019 positive regulation of retrograde axon cargo transport biological_process OBSOLETIONS =========== None TERM MERGES =========== GO:0000420, DNA-directed RNA polymerase IVa complex was merged into GO:0000418, DNA-directed RNA polymerase IV complex GO:0010953, regulation of protein maturation by peptide bond cleavage was merged into GO:0070613, regulation of protein processing GO:0051605, protein maturation by peptide bond cleavage was merged into GO:0016485, protein processing GO:0080137, DNA-directed RNA polymerase V complex was merged into GO:0000419, DNA-directed RNA polymerase V complex TERM CHANGES ============ GO:0000418 : DNA-directed RNA polymerase IV complex + alt_id: GO:0000420 - def: RNA polymerase IV is a multisubunit RNA polymerase complex found in the nucleus of plants. In addition to RNA polymerases I, II, and III, the essential RNA polymerases present in all eukaryotes, plants have two additional nuclear RNA polymerases, Pol IV and Pol V, that play nonredundant roles in siRNA-directed DNA methylation and gene silencing. Pol IV is required for siRNA production and Pol V is required for generating noncoding transcripts at target loci. Pol IV is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. The largest and second-largest subunits of Pol IV are the catalytic subunits and share similarity with the corresponding subunits of other eukaryotic and bacterial multisubunit RNA polymerases. + def: RNA polymerase IV is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol IV is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. The largest and second-largest subunits of Pol IV are the catalytic subunits and share similarity with the corresponding subunits of other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase V, while the largest subunit is found only in RNAP IV complex. + synonym: "DNA-directed RNA polymerase IVa complex" EXACT [] GO:0000419 : DNA-directed RNA polymerase V complex - name: DNA-directed RNA polymerase IVb complex + name: DNA-directed RNA polymerase V complex + alt_id: GO:0080137 - def: RNA polymerase IVb is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase IVa, while the largest subunit is found only in the IVa complex and contains an extended C-terminal domain (CTD) that includes multiple repeats of a 16 amino-acid consensus sequence as well as other sequences. The remainder of the complex is composed of smaller subunits. + def: RNA polymerase V is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol V is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase IVa, while the largest subunit is found only in the IVa complex and contains an extended C-terminal domain (CTD) that includes multiple repeats of a 16 amino-acid consensus sequence as well as other sequences. The remainder of the complex is composed of smaller subunits. + synonym: "DNA-directed RNA polymerase IVb complex" EXACT [] - is_a: GO:0000418 + is_a: GO:0055029 GO:0000785 : chromatin - def: The ordered and organized complex of DNA and protein that forms the chromosome. + def: The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. GO:0000789 : cytoplasmic chromatin - def: The ordered and organized complex of DNA and protein that forms the chromosome in the cytoplasm. + def: The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the cytoplasm. GO:0000790 : nuclear chromatin - def: The ordered and organized complex of DNA and protein that forms the chromosome in the nucleus. + def: The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus. GO:0000825 : inositol tetrakisphosphate 6-kinase activity + xref: MetaCyc:RXN-7184 GO:0000830 : inositol hexakisphosphate 4-kinase activity - is_a: GO:0033187 + is_a: GO:0000828 GO:0000831 : inositol hexakisphosphate 6-kinase activity - is_a: GO:0033187 + is_a: GO:0000828 GO:0000832 : inositol hexakisphosphate 5-kinase activity + xref: KEGG:R09087 GO:0000833 : inositol heptakisphosphate 4-kinase activity - is_a: GO:0033199 + is_a: GO:0000829 GO:0000834 : inositol heptakisphosphate 6-kinase activity - is_a: GO:0033199 + is_a: GO:0000829 GO:0000903 : regulation of cell shape during vegetative growth phase + relationship: part_of GO:0072690 GO:0000988 : protein binding transcription factor activity - def: Interacting selectively and non-covalently with two or more protein molecules, or a protein and another macromolecule or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. + def: Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. - relationship: has_part GO:0030674 + relationship: has_part GO:0005515 GO:0000989 : transcription factor binding transcription factor activity - def: Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. + def: Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0000990 : core RNA polymerase binding transcription factor activity - def: Interacting selectively and non-covalently with an RNA polymerase and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. + def: Interacting selectively and non-covalently with an RNA polymerase in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0000991 : core RNA polymerase II binding transcription factor activity - def: Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. + def: Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0000995 : core RNA polymerase III binding transcription factor activity - def: Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. + def: Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0001007 : RNA polymerase III transcription factor binding transcription factor activity - def: Interacting selectively and non-covalently with an RNA polymerase III transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. + def: Interacting selectively and non-covalently with an RNA polymerase III transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0001076 : RNA polymerase II transcription factor binding transcription factor activity - def: Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. + def: Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0001082 : RNA polymerase I transcription factor binding transcription factor activity - def: Interacting selectively and non-covalently with an RNA polymerase I transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. + def: Interacting selectively and non-covalently with an RNA polymerase I transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. + relationship: has_part GO:0001179 + relationship: part_of GO:0006360 GO:0001083 : RNA polymerase II basal transcription factor binding transcription factor activity - def: Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. + def: Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. GO:0001164 : RNA polymerase I core promoter sequence-specific DNA binding + synonym: "RNA polymerase I CORE element sequence-specific DNA binding" EXACT [] GO:0001169 : RNA polymerase I core promoter sequence-specific DNA binding transcription factor activity + synonym: "RNA polymerase I CORE element sequence-specific DNA binding transcription factor activity" EXACT [] GO:0002192 : IRES-dependent translational initiation - def: The process where translation initiation recruits the 40S ribosomal\n\nsubunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation. + def: The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation. GO:0002541 : activation of plasma proteins involved in acute inflammatory response - is_a: GO:0051605 + is_a: GO:0016485 GO:0003682 : chromatin binding - def: Interacting selectively and non-covalently with chromatin, the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase. + def: Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. GO:0004352 : glutamate dehydrogenase (NAD+) activity - name: glutamate dehydrogenase activity + name: glutamate dehydrogenase (NAD+) activity GO:0004446 : inositol-hexakisphosphate phosphatase activity - name: multiple inositol-polyphosphate phosphatase activity + name: inositol-hexakisphosphate phosphatase activity - synonym: "MIPP activity" EXACT [EC:3.1.3.62] - synonym: "1D-myo-inositol-hexakisphosphate 5-phosphohydrolase activity" EXACT [EC:3.1.3.62] - synonym: "inositol tetrakisphosphate phosphomonoesterase activity" EXACT [EC:3.1.3.62] + synonym: "MIPP activity" BROAD [EC:3.1.3.62] + synonym: "inositol tetrakisphosphate phosphomonoesterase activity" RELATED [EC:3.1.3.62] + synonym: "multiple inositol-polyphosphate phosphatase activity" BROAD [EC:3.1.3.62] + synonym: "1D-myo-inositol-hexakisphosphate 5-phosphohydrolase activity" NARROW [EC:3.1.3.62] GO:0004730 : pseudouridylate synthase activity + synonym: "pseudouridine-5'-phosphate glycosidase activity" EXACT [] GO:0004764 : shikimate 3-dehydrogenase (NADP+) activity - name: shikimate 5-dehydrogenase activity + name: shikimate 3-dehydrogenase (NADP+) activity - def: Catalysis of the reaction: shikimate + NADP+ = 5-dehydroshikimate + NADPH + H+. + def: Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+. - synonym: "shikimate oxidoreductase activity" EXACT [EC:1.1.1.25] - synonym: "DHS reductase activity" EXACT [EC:1.1.1.25] - synonym: "shikimate:NADP(+) oxidoreductase activity" EXACT [EC:1.1.1.25] - synonym: "dehydroshikimic reductase activity" EXACT [EC:1.1.1.25] + synonym: "shikimate:NADP(+) oxidoreductase activity" BROAD [EC:1.1.1.25] + synonym: "DHS reductase activity" BROAD [EC:1.1.1.25] + synonym: "shikimate oxidoreductase activity" BROAD [EC:1.1.1.25] + synonym: "dehydroshikimic reductase activity" BROAD [EC:1.1.1.25] + xref: KEGG:R06847 + xref: EC:1.1.1.282 + xref: RHEA:17740 GO:0005006 : epidermal growth factor-activated receptor activity - name: epidermal growth factor receptor activity + name: epidermal growth factor-activated receptor activity - def: Combining with an epidermal growth factor to initiate a change in cell activity. + def: Combining with an epidermal growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. + comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand EGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888. + synonym: "epidermal growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] + relationship: has_part GO:0048408 GO:0005007 : fibroblast growth factor-activated receptor activity - name: fibroblast growth factor receptor activity + name: fibroblast growth factor-activated receptor activity - def: Combining with fibroblast growth factor to initiate a change in cell activity. + def: Combining with a fibroblast growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. + comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand FGF. For receptors that bind other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888. + synonym: "FGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling] + synonym: "fibroblast growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] + relationship: has_part GO:0017134 GO:0005008 : hepatocyte growth factor-activated receptor activity - name: hepatocyte growth factor receptor activity + name: hepatocyte growth factor-activated receptor activity - def: Combining with hepatocye growth factor to initiate a change in cell activity. + def: Combining with hepatocyte growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. + comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand HGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888. + synonym: "HGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling] + synonym: "hepatocyte growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] GO:0005009 : insulin-activated receptor activity - name: insulin receptor activity + name: insulin-activated receptor activity - def: Combining with insulin to initiate a change in cell activity. + def: Combining with insulin and transmitting the signal across the plasma membrane to initiate a change in cell activity. + comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand insulin. For receptors that bind other extracellular ligands, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888. + synonym: "insulin receptor activity" EXACT [GOC:bf, GOC:signaling] + relationship: has_part GO:0043559 GO:0005010 : insulin-like growth factor-activated receptor activity - name: insulin-like growth factor receptor activity + name: insulin-like growth factor-activated receptor activity - def: Combining with an insulin-like growth factor to initiate a change in cell activity. + def: Combining with insulin-like growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. + comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand IGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888. + synonym: "IGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling] + synonym: "" RELATED [] + synonym: "insulin-like growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] + relationship: has_part GO:0005520 GO:0005017 : platelet-derived growth factor-activated receptor activity - name: platelet-derived growth factor receptor activity + name: platelet-derived growth factor-activated receptor activity - def: Combining with platelet-derived growth factor to initiate a change in cell activity. + def: Combining with platelet-derived growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. + comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand PDGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888. + synonym: "platelet-derived growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] + synonym: "PDGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling] + relationship: has_part GO:0048407 GO:0005021 : vascular endothelial growth factor-activated receptor activity - name: vascular endothelial growth factor receptor activity + name: vascular endothelial growth factor-activated receptor activity - def: Combining with vascular endothelial growth factor to initiate a change in cell activity. + def: Combining with vascular endothelial growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. + comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand VEGF. For receptors that bind other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888. + synonym: "VEGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling] + synonym: "vascular endothelial growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] GO:0005024 : transforming growth factor beta-activated receptor activity - name: transforming growth factor beta receptor activity + name: transforming growth factor beta-activated receptor activity + comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand TGFbeta. For binding to other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888. + synonym: "TGFbeta-activated receptor activity" EXACT [GOC:bf, GOC:signaling] + synonym: "transforming growth factor beta receptor activity" EXACT [GOC:bf, GOC:signaling] + relationship: has_part GO:0050431 GO:0005971 : ribonucleoside-diphosphate reductase complex + synonym: "RNR complex" EXACT [GOC:mah] + synonym: "ribonucleotide reductase complex" EXACT [GOC:mah] GO:0006465 : signal peptide processing - is_a: GO:0051605 + is_a: GO:0016485 GO:0006510 : ATP-dependent proteolysis - consider: GO:0051605 + consider: GO:0016485 GO:0006517 : protein deglycosylation - is_a: GO:0006516 GO:0007165 : signal transduction + relationship: part_of GO:0007154 GO:0007175 : negative regulation of epidermal growth factor-activated receptor activity - name: negative regulation of epidermal growth factor receptor activity + name: negative regulation of epidermal growth factor-activated receptor activity - def: Any process that stops, prevents, or reduces the frequency, rate or extent of EGF receptor activity. + def: Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity. + synonym: "negative regulation of epidermal growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] GO:0007176 : regulation of epidermal growth factor-activated receptor activity - name: regulation of epidermal growth factor receptor activity + name: regulation of epidermal growth factor-activated receptor activity - def: Any process that modulates the frequency, rate or extent of EGF receptor activity. + def: Any process that modulates the frequency, rate or extent of EGF-activated receptor activity. + synonym: "regulation of epidermal growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] GO:0007366 : periodic partitioning by pair rule gene + is_a: GO:0009952 GO:0007386 : compartment pattern specification - name: compartment pattern formation + name: compartment pattern specification GO:0007448 : anterior/posterior pattern specification, imaginal disc - name: anterior/posterior pattern formation, imaginal disc + name: anterior/posterior pattern specification, imaginal disc GO:0008313 : gurken-activated receptor activity - name: gurken receptor activity + name: gurken-activated receptor activity + synonym: "gurken receptor activity" EXACT [GOC:bf, GOC:signaling] GO:0008934 : inositol monophosphate phosphatase activity - name: inositol-1(or 4)-monophosphatase activity + name: inositol monophosphate phosphatase activity - synonym: "inositol monophosphate phosphatase activity" BROAD [EC:3.1.3.25] + synonym: "inositol-1(or 4)-monophosphatase activity" BROAD [EC:3.1.3.25] GO:0009952 : anterior/posterior pattern specification - name: anterior/posterior pattern formation + name: anterior/posterior pattern specification - synonym: "anterior/posterior pattern specification" NARROW [] + synonym: "anterior/posterior pattern formation" RELATED [] GO:0009955 : adaxial/abaxial pattern specification - name: adaxial/abaxial pattern formation + name: adaxial/abaxial pattern specification - synonym: "adaxial/abaxial pattern specification" NARROW [] + synonym: "adaxial/abaxial pattern formation" RELATED [] GO:0010448 : vegetative meristem growth + is_a: GO:0080186 GO:0010496 : intercellular transport - is_a: GO:0032501 + is_a: GO:0009987 GO:0010755 : regulation of plasminogen activation - is_a: GO:0010953 + is_a: GO:0070613 GO:0010954 : positive regulation of protein processing - name: positive regulation of protein maturation by peptide bond cleavage + name: positive regulation of protein processing + synonym: "positive regulation of protein maturation by peptide bond cleavage" EXACT [GOC:bf] - is_a: GO:0045862 - is_a: GO:0010953 + is_a: GO:0070613 - intersection_of: positively_regulates GO:0051605 + intersection_of: positively_regulates GO:0016485 - relationship: positively_regulates GO:0051605 + relationship: positively_regulates GO:0016485 GO:0010955 : negative regulation of protein processing - name: negative regulation of protein maturation by peptide bond cleavage + name: negative regulation of protein processing + synonym: "negative regulation of protein maturation by peptide bond cleavage" EXACT [GOC:bf] - is_a: GO:0045861 - is_a: GO:0010953 + is_a: GO:0070613 - intersection_of: negatively_regulates GO:0051605 + intersection_of: negatively_regulates GO:0016485 - relationship: negatively_regulates GO:0051605 + relationship: negatively_regulates GO:0016485 GO:0014889 : muscle atrophy + comment: GO:0014889 should only be used for annotation when muscle atrophy is a normal physiological process and not a disease process. GO:0016485 : protein processing + alt_id: GO:0051605 - def: Any protein maturation process achieved by the cleavage of peptide bonds. + def: Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein. + synonym: "peptidolysis during protein maturation" RELATED [GOC:mah] + synonym: "protein maturation by peptide bond cleavage" EXACT [GOC:bf] + synonym: "protein maturation by peptide bond hydrolysis" EXACT [GOC:mah] + synonym: "protein maturation by proteolysis" RELATED [GOC:mah] GO:0016486 : peptide hormone processing - is_a: GO:0051605 + is_a: GO:0016485 GO:0016568 : chromatin modification - def: The alteration of DNA or protein in chromatin, which may result in changing the chromatin structure. + def: The alteration of DNA, protein, or sometimes RNA, in chromatin, which may result in changing the chromatin structure. GO:0017002 : activin-activated receptor activity - name: activin receptor activity + name: activin-activated receptor activity + comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand activin. For binding to other extracellular ligands, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888. + synonym: "activin receptor activity" EXACT [GOC:bf, GOC:signaling] + relationship: has_part GO:0048185 GO:0017174 : glycine N-methyltransferase activity + xref: KEGG:R00367 + xref: RHEA:19940 + xref: MetaCyc:2.1.1.162-RXN + xref: EC:2.1.1.162 + xref: EC:2.1.1.156 GO:0017177 : glucosidase II complex - name: alpha-glucosidase II complex + name: glucosidase II complex + synonym: "alpha-glucosidase II complex" RELATED [GOC:19605557, GOC:vw] GO:0018456 : aryl-alcohol dehydrogenase (NAD+) activity - name: aryl-alcohol dehydrogenase activity + name: aryl-alcohol dehydrogenase (NAD+) activity GO:0021797 : forebrain anterior/posterior pattern specification - name: forebrain anterior/posterior pattern formation + name: forebrain anterior/posterior pattern specification - synonym: "forebrain anterior-posterior pattern formation" EXACT [] + synonym: "forebrain anterior-posterior pattern specification" EXACT [] GO:0030266 : quinate 3-dehydrogenase (NAD+) activity - name: quinate 5-dehydrogenase activity + name: quinate 3-dehydrogenase (NAD+) activity - def: Catalysis of the reaction: quinate + NAD+ = 5-dehydroquinate + NADH + H+. + def: Catalysis of the reaction: (-)-quinate + NAD+ = (-)-3-dehydroquinate + NADH + H+. - synonym: "quinate:NAD oxidoreductase activity" EXACT [EC:1.1.1.24] - synonym: "quinic dehydrogenase activity" EXACT [EC:1.1.1.24] + synonym: "quinate:NAD 5-oxidoreductase activity" EXACT [EC:1.1.1.24] + synonym: "quinate:NAD 3-oxidoreductase activity" EXACT [] + synonym: "quinate:NAD(+) 3-oxidoreductase activity" EXACT [] + synonym: "quinic dehydrogenase activity" BROAD [EC:1.1.1.24] + xref: RHEA:22367 + xref: KEGG:R01872 + xref: EC:1.1.1.282 GO:0030449 : regulation of complement activation - is_a: GO:0010953 + is_a: GO:0070613 GO:0031315 : extrinsic to mitochondrial outer membrane + relationship: part_of GO:0005741 GO:0031497 : chromatin assembly - def: The assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus. + def: The assembly of DNA, histone proteins, other associated proteins, and sometimes RNA, into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus. GO:0031498 : chromatin disassembly - def: The controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, and other proteins. + def: The controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, other proteins, and sometimes RNA. GO:0031551 : regulation of brain-derived neurotrophic factor-activated receptor activity - name: regulation of brain-derived neurotrophic factor receptor activity + name: regulation of brain-derived neurotrophic factor-activated receptor activity - def: Any process that modulates the frequency, rate or extent of brain-derived neurotrophic factor receptor activity. + def: Any process that modulates the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity. + synonym: "regulation of brain-derived neurotrophic factor receptor activity" EXACT [GOC:bf, GOC:signaling] GO:0031552 : negative regulation of brain-derived neurotrophic factor-activated receptor activity - name: negative regulation of brain-derived neurotrophic factor receptor activity + name: negative regulation of brain-derived neurotrophic factor-activated receptor activity - def: Any process that stops, prevents, or reduces the frequency, rate or extent of brain-derived neurotrophic factor receptor activity. + def: Any process that stops, prevents, or reduces the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity. + synonym: "negative regulation of brain-derived neurotrophic factor receptor activity" EXACT [GOC:bf, GOC:signaling] GO:0031553 : positive regulation of brain-derived neurotrophic factor-activated receptor activity - name: positive regulation of brain-derived neurotrophic factor receptor activity + name: positive regulation of brain-derived neurotrophic factor-activated receptor activity - def: Any process that activates or increases the frequency, rate or extent of brain-derived neurotrophic factor receptor activity. + def: Any process that activates or increases the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity. + synonym: "positive regulation of brain-derived neurotrophic factor receptor activity" EXACT [GOC:bf, GOC:signaling] GO:0031638 : zymogen activation - is_a: GO:0051605 + is_a: GO:0016485 GO:0032005 : signal transduction involved in conjugation with cellular fusion - name: regulation of conjugation with cellular fusion by signal transduction + name: signal transduction involved in conjugation with cellular fusion - is_a: GO:0031137 + relationship: part_of GO:0000747 GO:0032440 : 2-alkenal reductase [NAD(P)] activity - name: 2-alkenal reductase activity + name: 2-alkenal reductase [NAD(P)] activity GO:0032905 : transforming growth factor beta1 production - name: transforming growth factor-beta1 production + name: transforming growth factor beta1 production + synonym: "transforming growth factor-beta1 production" EXACT [GOC:bf] GO:0032906 : transforming growth factor beta2 production - name: transforming growth factor-beta2 production + name: transforming growth factor beta2 production + synonym: "transforming growth factor-beta2 production" EXACT [GOC:bf] GO:0032907 : transforming growth factor beta3 production - name: transforming growth factor-beta3 production + name: transforming growth factor beta3 production + synonym: "transforming growth factor-beta3 production" EXACT [GOC:bf] GO:0032908 : regulation of transforming growth factor beta1 production - name: regulation of transforming growth factor-beta1 production + name: regulation of transforming growth factor beta1 production + synonym: "regulation of transforming growth factor-beta1 production" EXACT [GOC:bf] GO:0032909 : regulation of transforming growth factor beta2 production - name: regulation of transforming growth factor-beta2 production + name: regulation of transforming growth factor beta2 production + synonym: "regulation of transforming growth factor beta2 production" EXACT [GOC:bf] GO:0032910 : regulation of transforming growth factor beta3 production - name: regulation of transforming growth factor-beta3 production + name: regulation of transforming growth factor beta3 production + synonym: "regulation of transforming growth factor-beta3 production" EXACT [GOC:bf] GO:0032911 : negative regulation of transforming growth factor beta1 production - name: negative regulation of transforming growth factor-beta1 production + name: negative regulation of transforming growth factor beta1 production + synonym: "negative regulation of transforming growth factor-beta1 production" EXACT [GOC:bf] GO:0032912 : negative regulation of transforming growth factor beta2 production - name: negative regulation of transforming growth factor-beta2 production + name: negative regulation of transforming growth factor beta2 production + synonym: "negative regulation of transforming growth factor-beta2 production" EXACT [GOC:bf] GO:0032913 : negative regulation of transforming growth factor beta3 production - name: negative regulation of transforming growth factor-beta3 production + name: negative regulation of transforming growth factor beta3 production + synonym: "negative regulation of transforming growth factor-beta3 production" EXACT [GOC:bf] GO:0032914 : positive regulation of transforming growth factor beta1 production - name: positive regulation of transforming growth factor-beta1 production + name: positive regulation of transforming growth factor beta1 production - synonym: "activation of transforming growth factor-beta1 production" NARROW [] + synonym: "activation of transforming growth factor-beta1 production" NARROW [GOC:bf] GO:0032915 : positive regulation of transforming growth factor beta2 production - name: positive regulation of transforming growth factor-beta2 production + name: positive regulation of transforming growth factor beta2 production + synonym: "positive regulation of transforming growth factor beta2 production" EXACT [GOC:bf] GO:0032916 : positive regulation of transforming growth factor beta3 production - name: positive regulation of transforming growth factor-beta3 production + name: positive regulation of transforming growth factor beta3 production + synonym: "positive regulation of transforming growth factor beta3 production" EXACT [GOC:bf] GO:0033709 : D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity - def: Catalysis of the reactions: D-arabinitol + NADP+ = D-ribulose + NADPH + H+. + def: Catalysis of the reaction: D-arabinitol + NADP+ = D-ribulose + NADPH + H+. GO:0033903 : endo-1,3(4)-beta-glucanase activity - is_a: GO:0004553 + is_a: GO:0052736 GO:0033919 : glucan 1,3-alpha-glucosidase activity - synonym: "glucosidase II activity" EXACT [EC:3.2.1.84] + synonym: "glucosidase II activity" RELATED [EC:3.2.1.84, GOC:vw] GO:0033946 : xyloglucan-specific endo-beta-1,4-glucanase activity - is_a: GO:0004553 + is_a: GO:0052736 GO:0033950 : xyloglucan-specific exo-beta-1,4-glucanase activity - is_a: GO:0004553 + is_a: GO:0052736 GO:0035054 : embryonic heart tube anterior/posterior pattern specification - name: embryonic heart tube anterior/posterior pattern formation + name: embryonic heart tube anterior/posterior pattern specification GO:0035103 : sterol regulatory element binding protein cleavage - is_a: GO:0051605 + is_a: GO:0016485 GO:0035300 : inositol-1,3,4-trisphosphate 5/6-kinase activity - xref: Reactome:REACT_25214 "ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5/6-P4, Homo sapiens" GO:0035334 : Notch receptor processing, ligand-independent - is_a: GO:0051605 + is_a: GO:0016485 GO:0035551 : protein initiator methionine removal involved in protein maturation - is_a: GO:0051605 + is_a: GO:0016485 GO:0035561 : regulation of chromatin binding - def: Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase. + def: Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. GO:0035562 : negative regulation of chromatin binding - def: Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase. + def: Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. GO:0035563 : positive regulation of chromatin binding - def: Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase. + def: Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. GO:0035625 : epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway - name: epidermal growth factor receptor transactivation by G-protein coupled receptor signaling pathway + name: epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway - def: The process in which an epidermal growth factor receptor is activated via signaling events from a G-protein coupled receptor. This is an example of cross-talk between the EGFR and GPCR signaling pathways. + def: The process in which an epidermal growth factor-activated receptor is activated via signaling events from a G-protein coupled receptor. This is an example of cross-talk between the EGF and GPCR signaling pathways. + synonym: "epidermal growth factor receptor transactivation by G-protein coupled receptor signaling pathway" EXACT [GOC:bf, GOC:signaling] GO:0035630 : bone mineralization involved in bone maturation + intersection_of: GO:0030282 + intersection_of: part_of GO:0070977 GO:0035798 : 2-alkenal reductase (NADP+) activity - name: 2-alkenal reductase activity (NADP+) activity + name: 2-alkenal reductase (NADP+) activity GO:0038005 : peptide bond cleavage involved in epidermal growth factor receptor ligand maturation - is_a: GO:0051605 + is_a: GO:0016485 GO:0042790 : transcription of nuclear large rRNA transcript from RNA polymerase I promoter - name: transcription of nuclear rRNA large RNA polymerase I transcript + name: transcription of nuclear large rRNA transcript from RNA polymerase I promoter - def: The synthesis of the large ribosomal RNA (rRNA) transcript which encodes several rRNAs, e.g. in mammals 28S, 18S and 5.8S, from a nuclear DNA template. + def: The synthesis of the large ribosomal RNA (rRNA) transcript which encodes several rRNAs, e.g. in mammals 28S, 18S and 5.8S, from a nuclear DNA template transcribed by RNA polymerase I. GO:0042813 : Wnt-activated receptor activity - name: Wnt receptor activity + name: Wnt-activated receptor activity - def: Combining with a member of the Wnt family of signaling molecules to initiate a change in cell activity. + def: Combining with a Wnt protein and transmitting the signal across the plasma membrane to initiate a change in cell activity. + synonym: "Wnt receptor activity" EXACT [GOC:bf, GOC:signaling] + relationship: has_part GO:0017147 GO:0043957 : acryloyl-CoA reductase (NADP+) activity - name: acrylyl-CoA reductase (NADPH) activity + name: acryloyl-CoA reductase (NADP+) activity - def: Catalysis of the reaction: acrylyl-CoA + NADPH + H+ = propionyl-CoA + NADP+. + def: Catalysis of the reaction: acryloyl-CoA + NADPH + H+ = propionyl-CoA + NADP+. + synonym: "acryloyl-CoA reductase (NADPH) activity" EXACT [] + synonym: "acrylyl-CoA reductase (NADPH) activity" EXACT [] - xref: EC:1.3.1.- + xref: EC:1.3.1.84 + xref: KEGG:R00919 GO:0043958 : acryloyl-CoA reductase activity - def: Catalysis of the reaction: reduced electron transferring flavoprotein + NADH + acrylyl-CoA = NAD+ + oxidized electron transferring flavoprotein + propionyl-CoA. + def: Catalysis of the reaction: acryloyl-CoA + NADH + H+ + a reduced electron-transfer flavoprotein = propionyl-CoA + NAD+ + an oxidized electron-transfer flavoprotein. - xref: MetaCyc:CPLX-7247 - xref: EC:1.3.1.- + xref: MetaCyc:RXN-8568 + xref: EC:1.3.99.3 GO:0045741 : positive regulation of epidermal growth factor-activated receptor activity - name: positive regulation of epidermal growth factor receptor activity + name: positive regulation of epidermal growth factor-activated receptor activity - def: Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor activity. + def: Any process that activates or increases the frequency, rate or extent of EGF-activated receptor activity. + synonym: "positive regulation of epidermal growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] GO:0051286 : cell tip + comment: Note that this term differs from 'cell pole ; GO:0060187' in that it is applicable to a narrower range of cell shapes. - is_a: GO:0044464 + is_a: GO:0060187 GO:0052632 : citrate hydro-lyase (cis-aconitate-forming) activity - def: Catalysis of the reactions: citrate = cis-aconitate + H2O. + def: Catalysis of the reaction: citrate = cis-aconitate + H2O. GO:0052662 : zeaxanthin epoxidase activity - def: Catalysis of the reactions: zeaxanthin + NAD(P)H + H+ + O2 = antheraxanthin + NAD(P)+ + H2O. + def: Catalysis of the reaction: zeaxanthin + NAD(P)H + H+ + O2 = antheraxanthin + NAD(P)+ + H2O. GO:0060175 : brain-derived neurotrophic factor-activated receptor activity - name: brain-derived neurotrophic factor receptor activity + name: brain-derived neurotrophic factor-activated receptor activity - def: Combining with brain-derived neurotrophic factor, to block apoptosis in neurons and promote nerve growth, or to initiate a change in cell activity. + def: Combining with a brain-derived neurotrophic factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. + comment: Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand BDNF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888. + synonym: "brain-derived neurotrophic factor receptor activity" EXACT [GOC:bf, GOC:signaling] + synonym: "BDNF-activated receptor activity" EXACT [GOC:bf, GOC:signaling] + relationship: has_part GO:0048403 GO:0060187 : cell pole + comment: Note that this term differs from 'cell tip ; GO:0051286' in that it is applicable to a broader range of cell shapes. GO:0060568 : regulation of peptide hormone processing - is_a: GO:0010953 + is_a: GO:0070613 GO:0061289 : Wnt receptor signaling pathway involved in kidney development + is_a: GO:0060995 - relationship: part_of GO:0001822 GO:0070613 : regulation of protein processing + alt_id: GO:0010953 - def: Any process that modulates the frequency, rate or extent of protein processing, the posttranslational modification of a protein leading to the attainment of the full functional capacity of the protein. + def: Any process that modulates the frequency, rate or extent of protein processing, any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. + synonym: "regulation of protein maturation by peptide bond cleavage" EXACT [] GO:0071586 : CAAX-box protein processing - is_a: GO:0051605 + is_a: GO:0016485 GO:0071604 : transforming growth factor beta production - name: transforming growth factor-beta production + name: transforming growth factor beta production + synonym: "transforming growth factor-beta production" EXACT [GOC:bf] GO:0071634 : regulation of transforming growth factor beta production - name: regulation of transforming growth factor-beta production + name: regulation of transforming growth factor beta production + synonym: "regulation of transforming growth factor-beta production" EXACT [GOC:bf] GO:0071635 : negative regulation of transforming growth factor beta production - name: negative regulation of transforming growth factor-beta production + name: negative regulation of transforming growth factor beta production + synonym: "negative regulation of transforming growth factor-beta production" EXACT [GOC:bf] GO:0071636 : positive regulation of transforming growth factor beta production - name: positive regulation of transforming growth factor-beta production + name: positive regulation of transforming growth factor beta production + synonym: "positive regulation of transforming growth factor-beta production" EXACT [GOC:bf] GO:0072043 : regulation of pre-tubular aggregate formation by cell-cell signaling - def: Any process that mediates the transfer of information from one cell to another that modulates the rate, frequency, or extent of pre-tubular aggregate formation. Pre-tubular aggregate formation is the cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney. + def: Any process that mediates the transfer of information from one cell to another that modulates the rate, frequency, or extent of pre-tubular aggregate formation. Pre-tubular aggregate formation is the cell adhesion process in which mesenchymal cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney. GO:0072168 : specification of anterior mesonephric tubule identity + is_a: GO:0072098 GO:0072169 : specification of posterior mesonephric tubule identity + is_a: GO:0072098 GO:0072689 : MCM complex assembly - def: The aggregation, arrangement and bonding together of a set of components to form an MCM complex, a hexameric protein complex required for the initiation and regulation of DNA replication. + def: The aggregation, arrangement and bonding together of a set of components to form an MCM complex, a hexameric protein complex required for the initiation and regulation of DNA replication. GO:0080120 : CAAX-box protein maturation - relationship: has_part GO:0051605 + relationship: has_part GO:0016485 GO:0080184 : response to phenylpropanoid - def: Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a phenylpropanoid stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. A phenylpropoanoid is any of secondary metabolites with structures based on a phenylpropane skeleton. The class includes phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules. Phenylpropanoids are also precursors of lignin. + def: Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a phenylpropanoid stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. A phenylpropanoid is any of secondary metabolites with structures based on a phenylpropane skeleton. The class includes phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules. Phenylpropanoids are also precursors of lignin. OTHER STANZA TYPES ================== Stanzas Edited ============== Stanza type ID Name Typedef occurs_in occurs in FILE STATS ========== Term counts for the old and new files Ontology Old file New file Change molecular function 9043 9062 +19 (9043 defined) (9062 defined) cellular component 2892 2892 (2892 defined) (2892 defined) biological process 21317 21330 +13 (21317 defined) (21330 defined) Obsolete 1564 1564 0 (4.5% of total) (4.5% of total) (0.0%) Totals 33252 33284 +32 (+0.1%) 33252 (100.0%) defined 33284 (100.0%) defined 34816 inc. obs 34848 inc. obs