Gene Ontology: Ontology Comparison Report

Files used:

file 1 (old): go-2011-08-13.obo; date: 12:08:2011 16:34; CVS revision: 1.2181
file 2 (new): go-2011-08-20.obo; date: 19:08:2011 16:54; CVS revision: 1.2200

New terms
Obsoletions
Term merges
Term changes
Other Stanza Types
File Stats

New terms

ID	name	namespace
GO:0001179	RNA polymerase I transcription factor binding	molecular_function
GO:0001180	transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript	biological_process
GO:0001181	core RNA polymerase I binding transcription factor activity	molecular_function
GO:0001182	promoter clearance from RNA polymerase I promoter	biological_process
GO:0001183	transcription elongation from RNA polymerase I promoter for nuclear large rRNA transcript	biological_process
GO:0001184	promoter clearance from RNA polymerase I promoter for nuclear large rRNA transcript	biological_process
GO:0001185	termination of RNA polymerase I transcription from promoter for nuclear large rRNA transcript	biological_process
GO:0035974	meiotic spindle pole body	cellular_component
GO:0035975	carbamoyl phosphate catabolic process	biological_process
GO:0035976	AP1 complex	cellular_component
GO:0035977	protein deglycosylation involved in glycoprotein catabolic process	biological_process
GO:0052719	apurinic/apyrimidinic endoribonuclease activity	molecular_function
GO:0052720	apurinic/apyrimidinic endodeoxyribonuclease activity	molecular_function
GO:0052721	regulation of apurinic/apyrimidinic endodeoxyribonuclease activity	biological_process
GO:0052722	fatty acid in-chain hydroxylase activity	molecular_function
GO:0052723	inositol hexakisphosphate 1-kinase activity	molecular_function
GO:0052724	inositol hexakisphosphate 3-kinase activity	molecular_function
GO:0052725	inositol-1,3,4-trisphosphate 6-kinase activity	molecular_function
GO:0052726	inositol-1,3,4-trisphosphate 5-kinase activity	molecular_function
GO:0052727	capsanthin synthase activity	molecular_function
GO:0052728	capsorubin synthase activity	molecular_function
GO:0052729	dimethylglycine N-methyltransferase activity	molecular_function
GO:0052730	sarcosine N-methyltransferase activity	molecular_function
GO:0052731	phosphocholine phosphatase activity	molecular_function
GO:0052732	phosphoethanolamine phosphatase activity	molecular_function
GO:0052733	quinate 3-dehydrogenase (NADP+) activity	molecular_function
GO:0052734	shikimate 3-dehydrogenase (NAD+) activity	molecular_function
GO:0052735	tRNA (cytosine-3-)-methyltransferase activity	molecular_function
GO:0052736	beta-glucanase activity	molecular_function
GO:0072690	vegetative growth of a single-celled organism	biological_process
GO:0072691	initiation of premeiotic DNA replication	biological_process
GO:0080186	developmental vegetative growth	biological_process
GO:2001013	epithelial cell proliferation involve in renal tubule morphogenesis	biological_process
GO:2001017	regulation of retrograde axon cargo transport	biological_process
GO:2001018	negative regulation of retrograde axon cargo transport	biological_process
GO:2001019	positive regulation of retrograde axon cargo transport	biological_process

Obsoletions

None

Term merges

Old ID	Old name	Merged into	Merged term name
GO:0000420	DNA-directed RNA polymerase IVa complex	GO:0000418	DNA-directed RNA polymerase IV complex
GO:0010953	regulation of protein maturation by peptide bond cleavage	GO:0070613	regulation of protein processing
GO:0051605	protein maturation by peptide bond cleavage	GO:0016485	protein processing
GO:0080137	DNA-directed RNA polymerase V complex	GO:0000419	DNA-directed RNA polymerase V complex

Term changes

Changes in term-related data
File 1 (12:08:2011 16:34, 1.2181)	File 2 (19:08:2011 16:54, 1.2200)

GO:0000418 : DNA-directed RNA polymerase IV complex
def RNA polymerase IV is a multisubunit RNA polymerase complex found in the nucleus of plants. In addition to RNA polymerases I, II, and III, the essential RNA polymerases present in all eukaryotes, plants have two additional nuclear RNA polymerases, Pol IV and Pol V, that play nonredundant roles in siRNA-directed DNA methylation and gene silencing. Pol IV is required for siRNA production and Pol V is required for generating noncoding transcripts at target loci. Pol IV is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. The largest and second-largest subunits of Pol IV are the catalytic subunits and share similarity with the corresponding subunits of other eukaryotic and bacterial multisubunit RNA polymerases.	alt_id GO:0000420 def RNA polymerase IV is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol IV is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. The largest and second-largest subunits of Pol IV are the catalytic subunits and share similarity with the corresponding subunits of other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase V, while the largest subunit is found only in RNAP IV complex. synonym "DNA-directed RNA polymerase IVa complex" EXACT []

GO:0000418 : DNA-directed RNA polymerase IV complex

def
RNA polymerase IV is a multisubunit RNA polymerase complex found in the nucleus of plants. In addition to RNA polymerases I, II, and III, the essential RNA polymerases present in all eukaryotes, plants have two additional nuclear RNA polymerases, Pol IV and Pol V, that play nonredundant roles in siRNA-directed DNA methylation and gene silencing. Pol IV is required for siRNA production and Pol V is required for generating noncoding transcripts at target loci. Pol IV is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. The largest and second-largest subunits of Pol IV are the catalytic subunits and share similarity with the corresponding subunits of other eukaryotic and bacterial multisubunit RNA polymerases.

alt_id
GO:0000420
def
RNA polymerase IV is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol IV is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. The largest and second-largest subunits of Pol IV are the catalytic subunits and share similarity with the corresponding subunits of other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase V, while the largest subunit is found only in RNAP IV complex.
synonym
"DNA-directed RNA polymerase IVa complex" EXACT []

GO:0000419 : DNA-directed RNA polymerase V complex
name ~~DNA-directed RNA polymerase IVb complex~~ def RNA polymerase IVb is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase IVa, while the largest subunit is found only in the IVa complex and contains an extended C-terminal domain (CTD) that includes multiple repeats of a 16 amino-acid consensus sequence as well as other sequences. The remainder of the complex is composed of smaller subunits. is_a ~~GO:0000418~~	name DNA-directed RNA polymerase V complex alt_id GO:0080137 def RNA polymerase V is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol V is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase IVa, while the largest subunit is found only in the IVa complex and contains an extended C-terminal domain (CTD) that includes multiple repeats of a 16 amino-acid consensus sequence as well as other sequences. The remainder of the complex is composed of smaller subunits. synonym "DNA-directed RNA polymerase IVb complex" EXACT [] is_a GO:0055029

GO:0000419 : DNA-directed RNA polymerase V complex

name
~~DNA-directed RNA polymerase IVb complex~~
def
RNA polymerase IVb is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase IVa, while the largest subunit is found only in the IVa complex and contains an extended C-terminal domain (CTD) that includes multiple repeats of a 16 amino-acid consensus sequence as well as other sequences. The remainder of the complex is composed of smaller subunits.
is_a
~~GO:0000418~~

name
DNA-directed RNA polymerase V complex
alt_id
GO:0080137
def
RNA polymerase V is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol V is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase IVa, while the largest subunit is found only in the IVa complex and contains an extended C-terminal domain (CTD) that includes multiple repeats of a 16 amino-acid consensus sequence as well as other sequences. The remainder of the complex is composed of smaller subunits.
synonym
"DNA-directed RNA polymerase IVb complex" EXACT []
is_a
GO:0055029

GO:0000785 : chromatin
def ~~The ordered and organized complex of DNA and protein that forms the chromosome.~~	def The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.

GO:0000789 : cytoplasmic chromatin
def ~~The ordered and organized complex of DNA and protein that forms the chromosome in the cytoplasm.~~	def The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the cytoplasm.

GO:0000790 : nuclear chromatin
def ~~The ordered and organized complex of DNA and protein that forms the chromosome in the nucleus.~~	def The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.

GO:0000825 : inositol tetrakisphosphate 6-kinase activity
	xref MetaCyc:RXN-7184

GO:0000830 : inositol hexakisphosphate 4-kinase activity
is_a ~~GO:0033187~~	is_a GO:0000828

GO:0000831 : inositol hexakisphosphate 6-kinase activity
is_a ~~GO:0033187~~	is_a GO:0000828

GO:0000832 : inositol hexakisphosphate 5-kinase activity
	xref KEGG:R09087

GO:0000833 : inositol heptakisphosphate 4-kinase activity
is_a ~~GO:0033199~~	is_a GO:0000829

GO:0000834 : inositol heptakisphosphate 6-kinase activity
is_a ~~GO:0033199~~	is_a GO:0000829

GO:0000903 : regulation of cell shape during vegetative growth phase
	relationship part_of GO:0072690

GO:0000988 : protein binding transcription factor activity
def Interacting selectively and non-covalently with two or more protein molecules, or a protein and another macromolecule or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. relationship ~~has_part GO:0030674~~	def Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. relationship has_part GO:0005515

GO:0000988 : protein binding transcription factor activity

def
Interacting selectively and non-covalently with two or more protein molecules, or a protein and another macromolecule or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
relationship
~~has_part GO:0030674~~

def
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
relationship
has_part GO:0005515

GO:0000989 : transcription factor binding transcription factor activity
def Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	def Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0000989 : transcription factor binding transcription factor activity

def
Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

def
Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0000990 : core RNA polymerase binding transcription factor activity
def Interacting selectively and non-covalently with an RNA polymerase and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	def Interacting selectively and non-covalently with an RNA polymerase in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0000991 : core RNA polymerase II binding transcription factor activity
def Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	def Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0000991 : core RNA polymerase II binding transcription factor activity

def
Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

def
Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0000995 : core RNA polymerase III binding transcription factor activity
def Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	def Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0001007 : RNA polymerase III transcription factor binding transcription factor activity
def Interacting selectively and non-covalently with an RNA polymerase III transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	def Interacting selectively and non-covalently with an RNA polymerase III transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0001007 : RNA polymerase III transcription factor binding transcription factor activity

def
Interacting selectively and non-covalently with an RNA polymerase III transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

def
Interacting selectively and non-covalently with an RNA polymerase III transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0001076 : RNA polymerase II transcription factor binding transcription factor activity
def Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	def Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0001076 : RNA polymerase II transcription factor binding transcription factor activity

def
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

def
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0001082 : RNA polymerase I transcription factor binding transcription factor activity
def Interacting selectively and non-covalently with an RNA polymerase I transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	def Interacting selectively and non-covalently with an RNA polymerase I transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well. relationship has_part GO:0001179 part_of GO:0006360

GO:0001082 : RNA polymerase I transcription factor binding transcription factor activity

def
Interacting selectively and non-covalently with an RNA polymerase I transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

def
Interacting selectively and non-covalently with an RNA polymerase I transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
relationship
has_part GO:0001179
part_of GO:0006360

GO:0001083 : RNA polymerase II basal transcription factor binding transcription factor activity
def Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	def Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0001083 : RNA polymerase II basal transcription factor binding transcription factor activity

def
Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

def
Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.

GO:0001164 : RNA polymerase I core promoter sequence-specific DNA binding
	synonym "RNA polymerase I CORE element sequence-specific DNA binding" EXACT []

GO:0001169 : RNA polymerase I core promoter sequence-specific DNA binding transcription factor activity
	synonym "RNA polymerase I CORE element sequence-specific DNA binding transcription factor activity" EXACT []

GO:0002192 : IRES-dependent translational initiation
def The process where translation initiation recruits the 40S ribosomal\n\nsubunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation.	def The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation.

GO:0002541 : activation of plasma proteins involved in acute inflammatory response
is_a ~~GO:0051605~~	is_a GO:0016485

GO:0003682 : chromatin binding
def ~~Interacting selectively and non-covalently with chromatin, the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase.~~	def Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.

GO:0004352 : glutamate dehydrogenase (NAD+) activity
name ~~glutamate dehydrogenase activity~~	name glutamate dehydrogenase (NAD+) activity

GO:0004446 : inositol-hexakisphosphate phosphatase activity
name ~~multiple inositol-polyphosphate phosphatase activity~~ synonym ~~"1D-myo-inositol-hexakisphosphate 5-phosphohydrolase activity" EXACT [EC:3.1.3.62]~~ ~~"inositol tetrakisphosphate phosphomonoesterase activity" EXACT [EC:3.1.3.62]~~ ~~"MIPP activity" EXACT [EC:3.1.3.62]~~	name inositol-hexakisphosphate phosphatase activity synonym "1D-myo-inositol-hexakisphosphate 5-phosphohydrolase activity" NARROW [EC:3.1.3.62] "inositol tetrakisphosphate phosphomonoesterase activity" RELATED [EC:3.1.3.62] "MIPP activity" BROAD [EC:3.1.3.62] "multiple inositol-polyphosphate phosphatase activity" BROAD [EC:3.1.3.62]

GO:0004730 : pseudouridylate synthase activity
	synonym "pseudouridine-5'-phosphate glycosidase activity" EXACT []

GO:0004764 : shikimate 3-dehydrogenase (NADP+) activity
name ~~shikimate 5-dehydrogenase activity~~ def ~~Catalysis of the reaction: shikimate + NADP+ = 5-dehydroshikimate + NADPH + H+.~~ synonym ~~"dehydroshikimic reductase activity" EXACT [EC:1.1.1.25]~~ ~~"DHS reductase activity" EXACT [EC:1.1.1.25]~~ ~~"shikimate oxidoreductase activity" EXACT [EC:1.1.1.25]~~ ~~"shikimate:NADP(+) oxidoreductase activity" EXACT [EC:1.1.1.25]~~	name shikimate 3-dehydrogenase (NADP+) activity def Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+. synonym "dehydroshikimic reductase activity" BROAD [EC:1.1.1.25] "DHS reductase activity" BROAD [EC:1.1.1.25] "shikimate oxidoreductase activity" BROAD [EC:1.1.1.25] "shikimate:NADP(+) oxidoreductase activity" BROAD [EC:1.1.1.25] xref EC:1.1.1.282 KEGG:R06847 RHEA:17740

GO:0004764 : shikimate 3-dehydrogenase (NADP+) activity

name
~~shikimate 5-dehydrogenase activity~~
def
~~Catalysis of the reaction: shikimate + NADP+ = 5-dehydroshikimate + NADPH + H+.~~
synonym
~~"dehydroshikimic reductase activity" EXACT [EC:1.1.1.25]~~
~~"DHS reductase activity" EXACT [EC:1.1.1.25]~~
~~"shikimate oxidoreductase activity" EXACT [EC:1.1.1.25]~~
~~"shikimate:NADP(+) oxidoreductase activity" EXACT [EC:1.1.1.25]~~

name
shikimate 3-dehydrogenase (NADP+) activity
def
Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+.
synonym
"dehydroshikimic reductase activity" BROAD [EC:1.1.1.25]
"DHS reductase activity" BROAD [EC:1.1.1.25]
"shikimate oxidoreductase activity" BROAD [EC:1.1.1.25]
"shikimate:NADP(+) oxidoreductase activity" BROAD [EC:1.1.1.25]
xref
EC:1.1.1.282
KEGG:R06847
RHEA:17740

GO:0005006 : epidermal growth factor-activated receptor activity
name ~~epidermal growth factor receptor activity~~ def ~~Combining with an epidermal growth factor to initiate a change in cell activity.~~	name epidermal growth factor-activated receptor activity def Combining with an epidermal growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. comment Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand EGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888. synonym "epidermal growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] relationship has_part GO:0048408

GO:0005006 : epidermal growth factor-activated receptor activity

name
~~epidermal growth factor receptor activity~~
def
~~Combining with an epidermal growth factor to initiate a change in cell activity.~~

name
epidermal growth factor-activated receptor activity
def
Combining with an epidermal growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.
comment
Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand EGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.
synonym
"epidermal growth factor receptor activity" EXACT [GOC:bf, GOC:signaling]
relationship
has_part GO:0048408

GO:0005007 : fibroblast growth factor-activated receptor activity
name ~~fibroblast growth factor receptor activity~~ def ~~Combining with fibroblast growth factor to initiate a change in cell activity.~~	name fibroblast growth factor-activated receptor activity def Combining with a fibroblast growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. comment Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand FGF. For receptors that bind other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888. synonym "FGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling] "fibroblast growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] relationship has_part GO:0017134

GO:0005007 : fibroblast growth factor-activated receptor activity

name
~~fibroblast growth factor receptor activity~~
def
~~Combining with fibroblast growth factor to initiate a change in cell activity.~~

name
fibroblast growth factor-activated receptor activity
def
Combining with a fibroblast growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.
comment
Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand FGF. For receptors that bind other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.
synonym
"FGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling]
"fibroblast growth factor receptor activity" EXACT [GOC:bf, GOC:signaling]
relationship
has_part GO:0017134

GO:0005008 : hepatocyte growth factor-activated receptor activity
name ~~hepatocyte growth factor receptor activity~~ def ~~Combining with hepatocye growth factor to initiate a change in cell activity.~~	name hepatocyte growth factor-activated receptor activity def Combining with hepatocyte growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. comment Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand HGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888. synonym "hepatocyte growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] "HGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling]

GO:0005008 : hepatocyte growth factor-activated receptor activity

name
~~hepatocyte growth factor receptor activity~~
def
~~Combining with hepatocye growth factor to initiate a change in cell activity.~~

name
hepatocyte growth factor-activated receptor activity
def
Combining with hepatocyte growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.
comment
Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand HGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.
synonym
"hepatocyte growth factor receptor activity" EXACT [GOC:bf, GOC:signaling]
"HGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling]

GO:0005009 : insulin-activated receptor activity
name ~~insulin receptor activity~~ def ~~Combining with insulin to initiate a change in cell activity.~~	name insulin-activated receptor activity def Combining with insulin and transmitting the signal across the plasma membrane to initiate a change in cell activity. comment Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand insulin. For receptors that bind other extracellular ligands, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888. synonym "insulin receptor activity" EXACT [GOC:bf, GOC:signaling] relationship has_part GO:0043559

GO:0005009 : insulin-activated receptor activity

name
~~insulin receptor activity~~
def
~~Combining with insulin to initiate a change in cell activity.~~

name
insulin-activated receptor activity
def
Combining with insulin and transmitting the signal across the plasma membrane to initiate a change in cell activity.
comment
Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand insulin. For receptors that bind other extracellular ligands, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.
synonym
"insulin receptor activity" EXACT [GOC:bf, GOC:signaling]
relationship
has_part GO:0043559

GO:0005010 : insulin-like growth factor-activated receptor activity
name ~~insulin-like growth factor receptor activity~~ def ~~Combining with an insulin-like growth factor to initiate a change in cell activity.~~	name insulin-like growth factor-activated receptor activity def Combining with insulin-like growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. comment Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand IGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888. synonym "" RELATED [] "IGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling] "insulin-like growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] relationship has_part GO:0005520

GO:0005010 : insulin-like growth factor-activated receptor activity

name
~~insulin-like growth factor receptor activity~~
def
~~Combining with an insulin-like growth factor to initiate a change in cell activity.~~

name
insulin-like growth factor-activated receptor activity
def
Combining with insulin-like growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.
comment
Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand IGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.
synonym
"" RELATED []
"IGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling]
"insulin-like growth factor receptor activity" EXACT [GOC:bf, GOC:signaling]
relationship
has_part GO:0005520

GO:0005017 : platelet-derived growth factor-activated receptor activity
name ~~platelet-derived growth factor receptor activity~~ def ~~Combining with platelet-derived growth factor to initiate a change in cell activity.~~	name platelet-derived growth factor-activated receptor activity def Combining with platelet-derived growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. comment Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand PDGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888. synonym "PDGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling] "platelet-derived growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] relationship has_part GO:0048407

GO:0005017 : platelet-derived growth factor-activated receptor activity

name
~~platelet-derived growth factor receptor activity~~
def
~~Combining with platelet-derived growth factor to initiate a change in cell activity.~~

name
platelet-derived growth factor-activated receptor activity
def
Combining with platelet-derived growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.
comment
Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand PDGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.
synonym
"PDGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling]
"platelet-derived growth factor receptor activity" EXACT [GOC:bf, GOC:signaling]
relationship
has_part GO:0048407

GO:0005021 : vascular endothelial growth factor-activated receptor activity
name ~~vascular endothelial growth factor receptor activity~~ def ~~Combining with vascular endothelial growth factor to initiate a change in cell activity.~~	name vascular endothelial growth factor-activated receptor activity def Combining with vascular endothelial growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity. comment Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand VEGF. For receptors that bind other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888. synonym "vascular endothelial growth factor receptor activity" EXACT [GOC:bf, GOC:signaling] "VEGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling]

GO:0005021 : vascular endothelial growth factor-activated receptor activity

name
~~vascular endothelial growth factor receptor activity~~
def
~~Combining with vascular endothelial growth factor to initiate a change in cell activity.~~

name
vascular endothelial growth factor-activated receptor activity
def
Combining with vascular endothelial growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.
comment
Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand VEGF. For receptors that bind other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.
synonym
"vascular endothelial growth factor receptor activity" EXACT [GOC:bf, GOC:signaling]
"VEGF-activated receptor activity" EXACT [GOC:bf, GOC:signaling]

GO:0005024 : transforming growth factor beta-activated receptor activity
name ~~transforming growth factor beta receptor activity~~	name transforming growth factor beta-activated receptor activity comment Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand TGFbeta. For binding to other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888. synonym "TGFbeta-activated receptor activity" EXACT [GOC:bf, GOC:signaling] "transforming growth factor beta receptor activity" EXACT [GOC:bf, GOC:signaling] relationship has_part GO:0050431

GO:0005024 : transforming growth factor beta-activated receptor activity

name
~~transforming growth factor beta receptor activity~~

name
transforming growth factor beta-activated receptor activity
comment
Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand TGFbeta. For binding to other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.
synonym
"TGFbeta-activated receptor activity" EXACT [GOC:bf, GOC:signaling]
"transforming growth factor beta receptor activity" EXACT [GOC:bf, GOC:signaling]
relationship
has_part GO:0050431

GO:0005971 : ribonucleoside-diphosphate reductase complex
	synonym "ribonucleotide reductase complex" EXACT [GOC:mah] "RNR complex" EXACT [GOC:mah]

GO:0006465 : signal peptide processing
is_a ~~GO:0051605~~	is_a GO:0016485

GO:0006510 : ATP-dependent proteolysis
consider ~~GO:0051605~~	consider GO:0016485

GO:0006517 : protein deglycosylation
is_a ~~GO:0006516~~

GO:0007165 : signal transduction
	relationship part_of GO:0007154

GO:0007175 : negative regulation of epidermal growth factor-activated receptor activity
name ~~negative regulation of epidermal growth factor receptor activity~~ def ~~Any process that stops, prevents, or reduces the frequency, rate or extent of EGF receptor activity.~~	name negative regulation of epidermal growth factor-activated receptor activity def Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity. synonym "negative regulation of epidermal growth factor receptor activity" EXACT [GOC:bf, GOC:signaling]

GO:0007176 : regulation of epidermal growth factor-activated receptor activity
name ~~regulation of epidermal growth factor receptor activity~~ def ~~Any process that modulates the frequency, rate or extent of EGF receptor activity.~~	name regulation of epidermal growth factor-activated receptor activity def Any process that modulates the frequency, rate or extent of EGF-activated receptor activity. synonym "regulation of epidermal growth factor receptor activity" EXACT [GOC:bf, GOC:signaling]

GO:0007366 : periodic partitioning by pair rule gene
	is_a GO:0009952

GO:0007386 : compartment pattern specification
name ~~compartment pattern formation~~	name compartment pattern specification

GO:0007448 : anterior/posterior pattern specification, imaginal disc
name ~~anterior/posterior pattern formation, imaginal disc~~	name anterior/posterior pattern specification, imaginal disc

GO:0008313 : gurken-activated receptor activity
name ~~gurken receptor activity~~	name gurken-activated receptor activity synonym "gurken receptor activity" EXACT [GOC:bf, GOC:signaling]

GO:0008934 : inositol monophosphate phosphatase activity
name ~~inositol-1(or 4)-monophosphatase activity~~ synonym ~~"inositol monophosphate phosphatase activity" BROAD [EC:3.1.3.25]~~	name inositol monophosphate phosphatase activity synonym "inositol-1(or 4)-monophosphatase activity" BROAD [EC:3.1.3.25]

GO:0009952 : anterior/posterior pattern specification
name ~~anterior/posterior pattern formation~~ synonym ~~"anterior/posterior pattern specification" NARROW []~~	name anterior/posterior pattern specification synonym "anterior/posterior pattern formation" RELATED []

GO:0009955 : adaxial/abaxial pattern specification
name ~~adaxial/abaxial pattern formation~~ synonym ~~"adaxial/abaxial pattern specification" NARROW []~~	name adaxial/abaxial pattern specification synonym "adaxial/abaxial pattern formation" RELATED []

GO:0010448 : vegetative meristem growth
	is_a GO:0080186

GO:0010496 : intercellular transport
is_a ~~GO:0032501~~	is_a GO:0009987

GO:0010755 : regulation of plasminogen activation
is_a ~~GO:0010953~~	is_a GO:0070613

GO:0010954 : positive regulation of protein processing
name ~~positive regulation of protein maturation by peptide bond cleavage~~ is_a ~~GO:0010953~~ ~~GO:0045862~~ intersection_of ~~positively_regulates GO:0051605~~ relationship ~~positively_regulates GO:0051605~~	name positive regulation of protein processing synonym "positive regulation of protein maturation by peptide bond cleavage" EXACT [GOC:bf] is_a GO:0070613 intersection_of positively_regulates GO:0016485 relationship positively_regulates GO:0016485

GO:0010955 : negative regulation of protein processing
name ~~negative regulation of protein maturation by peptide bond cleavage~~ is_a ~~GO:0010953~~ ~~GO:0045861~~ intersection_of ~~negatively_regulates GO:0051605~~ relationship ~~negatively_regulates GO:0051605~~	name negative regulation of protein processing synonym "negative regulation of protein maturation by peptide bond cleavage" EXACT [GOC:bf] is_a GO:0070613 intersection_of negatively_regulates GO:0016485 relationship negatively_regulates GO:0016485

GO:0014889 : muscle atrophy
	comment GO:0014889 should only be used for annotation when muscle atrophy is a normal physiological process and not a disease process.

GO:0016485 : protein processing

def
~~Any protein maturation process achieved by the cleavage of peptide bonds.~~

alt_id
GO:0051605
def
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
synonym
"peptidolysis during protein maturation" RELATED [GOC:mah]
"protein maturation by peptide bond cleavage" EXACT [GOC:bf]
"protein maturation by peptide bond hydrolysis" EXACT [GOC:mah]
"protein maturation by proteolysis" RELATED [GOC:mah]

GO:0016486 : peptide hormone processing
is_a ~~GO:0051605~~	is_a GO:0016485

GO:0016568 : chromatin modification
def ~~The alteration of DNA or protein in chromatin, which may result in changing the chromatin structure.~~	def The alteration of DNA, protein, or sometimes RNA, in chromatin, which may result in changing the chromatin structure.

GO:0017002 : activin-activated receptor activity

name
~~activin receptor activity~~

name
activin-activated receptor activity
comment
Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand activin. For binding to other extracellular ligands, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.
synonym
"activin receptor activity" EXACT [GOC:bf, GOC:signaling]
relationship
has_part GO:0048185

GO:0017174 : glycine N-methyltransferase activity
	xref EC:2.1.1.156 EC:2.1.1.162 KEGG:R00367 MetaCyc:2.1.1.162-RXN RHEA:19940

GO:0017177 : glucosidase II complex
name ~~alpha-glucosidase II complex~~	name glucosidase II complex synonym "alpha-glucosidase II complex" RELATED [GOC:19605557, GOC:vw]

GO:0018456 : aryl-alcohol dehydrogenase (NAD+) activity
name ~~aryl-alcohol dehydrogenase activity~~	name aryl-alcohol dehydrogenase (NAD+) activity

GO:0021797 : forebrain anterior/posterior pattern specification
name ~~forebrain anterior/posterior pattern formation~~ synonym ~~"forebrain anterior-posterior pattern formation" EXACT []~~	name forebrain anterior/posterior pattern specification synonym "forebrain anterior-posterior pattern specification" EXACT []

GO:0030266 : quinate 3-dehydrogenase (NAD+) activity

name
~~quinate 5-dehydrogenase activity~~
def
~~Catalysis of the reaction: quinate + NAD+ = 5-dehydroquinate + NADH + H+.~~
synonym
~~"quinate:NAD oxidoreductase activity" EXACT [EC:1.1.1.24]~~
~~"quinic dehydrogenase activity" EXACT [EC:1.1.1.24]~~

name
quinate 3-dehydrogenase (NAD+) activity
def
Catalysis of the reaction: (-)-quinate + NAD+ = (-)-3-dehydroquinate + NADH + H+.
synonym
"quinate:NAD 3-oxidoreductase activity" EXACT []
"quinate:NAD 5-oxidoreductase activity" EXACT [EC:1.1.1.24]
"quinate:NAD(+) 3-oxidoreductase activity" EXACT []
"quinic dehydrogenase activity" BROAD [EC:1.1.1.24]
xref
EC:1.1.1.282
KEGG:R01872
RHEA:22367

GO:0030449 : regulation of complement activation
is_a ~~GO:0010953~~	is_a GO:0070613

GO:0031315 : extrinsic to mitochondrial outer membrane
	relationship part_of GO:0005741

GO:0031497 : chromatin assembly
def The assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus.	def The assembly of DNA, histone proteins, other associated proteins, and sometimes RNA, into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus.

GO:0031498 : chromatin disassembly
def ~~The controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, and other proteins.~~	def The controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, other proteins, and sometimes RNA.

GO:0031551 : regulation of brain-derived neurotrophic factor-activated receptor activity
name ~~regulation of brain-derived neurotrophic factor receptor activity~~ def ~~Any process that modulates the frequency, rate or extent of brain-derived neurotrophic factor receptor activity.~~	name regulation of brain-derived neurotrophic factor-activated receptor activity def Any process that modulates the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity. synonym "regulation of brain-derived neurotrophic factor receptor activity" EXACT [GOC:bf, GOC:signaling]

GO:0031552 : negative regulation of brain-derived neurotrophic factor-activated receptor activity
name ~~negative regulation of brain-derived neurotrophic factor receptor activity~~ def ~~Any process that stops, prevents, or reduces the frequency, rate or extent of brain-derived neurotrophic factor receptor activity.~~	name negative regulation of brain-derived neurotrophic factor-activated receptor activity def Any process that stops, prevents, or reduces the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity. synonym "negative regulation of brain-derived neurotrophic factor receptor activity" EXACT [GOC:bf, GOC:signaling]

GO:0031553 : positive regulation of brain-derived neurotrophic factor-activated receptor activity
name ~~positive regulation of brain-derived neurotrophic factor receptor activity~~ def ~~Any process that activates or increases the frequency, rate or extent of brain-derived neurotrophic factor receptor activity.~~	name positive regulation of brain-derived neurotrophic factor-activated receptor activity def Any process that activates or increases the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity. synonym "positive regulation of brain-derived neurotrophic factor receptor activity" EXACT [GOC:bf, GOC:signaling]

GO:0031638 : zymogen activation
is_a ~~GO:0051605~~	is_a GO:0016485

GO:0032005 : signal transduction involved in conjugation with cellular fusion
name ~~regulation of conjugation with cellular fusion by signal transduction~~ is_a ~~GO:0031137~~	name signal transduction involved in conjugation with cellular fusion relationship part_of GO:0000747

GO:0032440 : 2-alkenal reductase [NAD(P)] activity
name ~~2-alkenal reductase activity~~	name 2-alkenal reductase [NAD(P)] activity

GO:0032905 : transforming growth factor beta1 production
name ~~transforming growth factor-beta1 production~~	name transforming growth factor beta1 production synonym "transforming growth factor-beta1 production" EXACT [GOC:bf]

GO:0032906 : transforming growth factor beta2 production
name ~~transforming growth factor-beta2 production~~	name transforming growth factor beta2 production synonym "transforming growth factor-beta2 production" EXACT [GOC:bf]

GO:0032907 : transforming growth factor beta3 production
name ~~transforming growth factor-beta3 production~~	name transforming growth factor beta3 production synonym "transforming growth factor-beta3 production" EXACT [GOC:bf]

GO:0032908 : regulation of transforming growth factor beta1 production
name ~~regulation of transforming growth factor-beta1 production~~	name regulation of transforming growth factor beta1 production synonym "regulation of transforming growth factor-beta1 production" EXACT [GOC:bf]

GO:0032909 : regulation of transforming growth factor beta2 production
name ~~regulation of transforming growth factor-beta2 production~~	name regulation of transforming growth factor beta2 production synonym "regulation of transforming growth factor beta2 production" EXACT [GOC:bf]

GO:0032910 : regulation of transforming growth factor beta3 production
name ~~regulation of transforming growth factor-beta3 production~~	name regulation of transforming growth factor beta3 production synonym "regulation of transforming growth factor-beta3 production" EXACT [GOC:bf]

GO:0032911 : negative regulation of transforming growth factor beta1 production
name ~~negative regulation of transforming growth factor-beta1 production~~	name negative regulation of transforming growth factor beta1 production synonym "negative regulation of transforming growth factor-beta1 production" EXACT [GOC:bf]

GO:0032912 : negative regulation of transforming growth factor beta2 production
name ~~negative regulation of transforming growth factor-beta2 production~~	name negative regulation of transforming growth factor beta2 production synonym "negative regulation of transforming growth factor-beta2 production" EXACT [GOC:bf]

GO:0032913 : negative regulation of transforming growth factor beta3 production
name ~~negative regulation of transforming growth factor-beta3 production~~	name negative regulation of transforming growth factor beta3 production synonym "negative regulation of transforming growth factor-beta3 production" EXACT [GOC:bf]

GO:0032914 : positive regulation of transforming growth factor beta1 production
name ~~positive regulation of transforming growth factor-beta1 production~~ synonym ~~"activation of transforming growth factor-beta1 production" NARROW []~~	name positive regulation of transforming growth factor beta1 production synonym "activation of transforming growth factor-beta1 production" NARROW [GOC:bf]

GO:0032915 : positive regulation of transforming growth factor beta2 production
name ~~positive regulation of transforming growth factor-beta2 production~~	name positive regulation of transforming growth factor beta2 production synonym "positive regulation of transforming growth factor beta2 production" EXACT [GOC:bf]

GO:0032916 : positive regulation of transforming growth factor beta3 production
name ~~positive regulation of transforming growth factor-beta3 production~~	name positive regulation of transforming growth factor beta3 production synonym "positive regulation of transforming growth factor beta3 production" EXACT [GOC:bf]

GO:0033709 : D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity
def ~~Catalysis of the reactions: D-arabinitol + NADP+ = D-ribulose + NADPH + H+.~~	def Catalysis of the reaction: D-arabinitol + NADP+ = D-ribulose + NADPH + H+.

GO:0033903 : endo-1,3(4)-beta-glucanase activity
is_a ~~GO:0004553~~	is_a GO:0052736

GO:0033919 : glucan 1,3-alpha-glucosidase activity
synonym ~~"glucosidase II activity" EXACT [EC:3.2.1.84]~~	synonym "glucosidase II activity" RELATED [EC:3.2.1.84, GOC:vw]

GO:0033946 : xyloglucan-specific endo-beta-1,4-glucanase activity
is_a ~~GO:0004553~~	is_a GO:0052736

GO:0033950 : xyloglucan-specific exo-beta-1,4-glucanase activity
is_a ~~GO:0004553~~	is_a GO:0052736

GO:0035054 : embryonic heart tube anterior/posterior pattern specification
name ~~embryonic heart tube anterior/posterior pattern formation~~	name embryonic heart tube anterior/posterior pattern specification

GO:0035103 : sterol regulatory element binding protein cleavage
is_a ~~GO:0051605~~	is_a GO:0016485

GO:0035300 : inositol-1,3,4-trisphosphate 5/6-kinase activity
xref ~~Reactome:REACT_25214 "ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5/6-P4, Homo sapiens"~~

GO:0035334 : Notch receptor processing, ligand-independent
is_a ~~GO:0051605~~	is_a GO:0016485

GO:0035551 : protein initiator methionine removal involved in protein maturation
is_a ~~GO:0051605~~	is_a GO:0016485

GO:0035561 : regulation of chromatin binding
def Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase.	def Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.

GO:0035562 : negative regulation of chromatin binding
def Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase.	def Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.

GO:0035563 : positive regulation of chromatin binding
def Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA and protein that make up the chromosomes of the eukaryotic nucleus during interphase.	def Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.

GO:0035625 : epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway

name
~~epidermal growth factor receptor transactivation by G-protein coupled receptor signaling pathway~~
def
The process in which an epidermal growth factor receptor is activated via signaling events from a G-protein coupled receptor. This is an example of cross-talk between the EGFR and GPCR signaling pathways.

name
epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
def
The process in which an epidermal growth factor-activated receptor is activated via signaling events from a G-protein coupled receptor. This is an example of cross-talk between the EGF and GPCR signaling pathways.
synonym
"epidermal growth factor receptor transactivation by G-protein coupled receptor signaling pathway" EXACT [GOC:bf, GOC:signaling]

GO:0035630 : bone mineralization involved in bone maturation
	intersection_of GO:0030282 part_of GO:0070977

GO:0035798 : 2-alkenal reductase (NADP+) activity
name ~~2-alkenal reductase activity (NADP+) activity~~	name 2-alkenal reductase (NADP+) activity

GO:0038005 : peptide bond cleavage involved in epidermal growth factor receptor ligand maturation
is_a ~~GO:0051605~~	is_a GO:0016485

GO:0042790 : transcription of nuclear large rRNA transcript from RNA polymerase I promoter
name ~~transcription of nuclear rRNA large RNA polymerase I transcript~~ def ~~The synthesis of the large ribosomal RNA (rRNA) transcript which encodes several rRNAs, e.g. in mammals 28S, 18S and 5.8S, from a nuclear DNA template.~~	name transcription of nuclear large rRNA transcript from RNA polymerase I promoter def The synthesis of the large ribosomal RNA (rRNA) transcript which encodes several rRNAs, e.g. in mammals 28S, 18S and 5.8S, from a nuclear DNA template transcribed by RNA polymerase I.

GO:0042813 : Wnt-activated receptor activity
name ~~Wnt receptor activity~~ def ~~Combining with a member of the Wnt family of signaling molecules to initiate a change in cell activity.~~	name Wnt-activated receptor activity def Combining with a Wnt protein and transmitting the signal across the plasma membrane to initiate a change in cell activity. synonym "Wnt receptor activity" EXACT [GOC:bf, GOC:signaling] relationship has_part GO:0017147

GO:0043957 : acryloyl-CoA reductase (NADP+) activity
name ~~acrylyl-CoA reductase (NADPH) activity~~ def ~~Catalysis of the reaction: acrylyl-CoA + NADPH + H+ = propionyl-CoA + NADP+.~~ xref ~~EC:1.3.1.-~~	name acryloyl-CoA reductase (NADP+) activity def Catalysis of the reaction: acryloyl-CoA + NADPH + H+ = propionyl-CoA + NADP+. synonym "acryloyl-CoA reductase (NADPH) activity" EXACT [] "acrylyl-CoA reductase (NADPH) activity" EXACT [] xref EC:1.3.1.84 KEGG:R00919

GO:0043958 : acryloyl-CoA reductase activity
def ~~Catalysis of the reaction: reduced electron transferring flavoprotein + NADH + acrylyl-CoA = NAD+ + oxidized electron transferring flavoprotein + propionyl-CoA.~~ xref ~~EC:1.3.1.-~~ ~~MetaCyc:CPLX-7247~~	def Catalysis of the reaction: acryloyl-CoA + NADH + H+ + a reduced electron-transfer flavoprotein = propionyl-CoA + NAD+ + an oxidized electron-transfer flavoprotein. xref EC:1.3.99.3 MetaCyc:RXN-8568

GO:0045741 : positive regulation of epidermal growth factor-activated receptor activity
name ~~positive regulation of epidermal growth factor receptor activity~~ def ~~Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor activity.~~	name positive regulation of epidermal growth factor-activated receptor activity def Any process that activates or increases the frequency, rate or extent of EGF-activated receptor activity. synonym "positive regulation of epidermal growth factor receptor activity" EXACT [GOC:bf, GOC:signaling]

GO:0051286 : cell tip
is_a ~~GO:0044464~~	comment Note that this term differs from 'cell pole ; GO:0060187' in that it is applicable to a narrower range of cell shapes. is_a GO:0060187

GO:0052632 : citrate hydro-lyase (cis-aconitate-forming) activity
def ~~Catalysis of the reactions: citrate = cis-aconitate + H2O.~~	def Catalysis of the reaction: citrate = cis-aconitate + H2O.

GO:0052662 : zeaxanthin epoxidase activity
def ~~Catalysis of the reactions: zeaxanthin + NAD(P)H + H+ + O2 = antheraxanthin + NAD(P)+ + H2O.~~	def Catalysis of the reaction: zeaxanthin + NAD(P)H + H+ + O2 = antheraxanthin + NAD(P)+ + H2O.

GO:0060175 : brain-derived neurotrophic factor-activated receptor activity

name
~~brain-derived neurotrophic factor receptor activity~~
def
~~Combining with brain-derived neurotrophic factor, to block apoptosis in neurons and promote nerve growth, or to initiate a change in cell activity.~~

name
brain-derived neurotrophic factor-activated receptor activity
def
Combining with a brain-derived neurotrophic factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.
comment
Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand BDNF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.
synonym
"BDNF-activated receptor activity" EXACT [GOC:bf, GOC:signaling]
"brain-derived neurotrophic factor receptor activity" EXACT [GOC:bf, GOC:signaling]
relationship
has_part GO:0048403

GO:0060187 : cell pole
	comment Note that this term differs from 'cell tip ; GO:0051286' in that it is applicable to a broader range of cell shapes.

GO:0060568 : regulation of peptide hormone processing
is_a ~~GO:0010953~~	is_a GO:0070613

GO:0061289 : Wnt receptor signaling pathway involved in kidney development
relationship ~~part_of GO:0001822~~	is_a GO:0060995

GO:0070613 : regulation of protein processing
def Any process that modulates the frequency, rate or extent of protein processing, the posttranslational modification of a protein leading to the attainment of the full functional capacity of the protein.	alt_id GO:0010953 def Any process that modulates the frequency, rate or extent of protein processing, any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. synonym "regulation of protein maturation by peptide bond cleavage" EXACT []

GO:0071586 : CAAX-box protein processing
is_a ~~GO:0051605~~	is_a GO:0016485

GO:0071604 : transforming growth factor beta production
name ~~transforming growth factor-beta production~~	name transforming growth factor beta production synonym "transforming growth factor-beta production" EXACT [GOC:bf]

GO:0071634 : regulation of transforming growth factor beta production
name ~~regulation of transforming growth factor-beta production~~	name regulation of transforming growth factor beta production synonym "regulation of transforming growth factor-beta production" EXACT [GOC:bf]

GO:0071635 : negative regulation of transforming growth factor beta production
name ~~negative regulation of transforming growth factor-beta production~~	name negative regulation of transforming growth factor beta production synonym "negative regulation of transforming growth factor-beta production" EXACT [GOC:bf]

GO:0071636 : positive regulation of transforming growth factor beta production
name ~~positive regulation of transforming growth factor-beta production~~	name positive regulation of transforming growth factor beta production synonym "positive regulation of transforming growth factor-beta production" EXACT [GOC:bf]

GO:0072043 : regulation of pre-tubular aggregate formation by cell-cell signaling

def
Any process that mediates the transfer of information from one cell to another that modulates the rate, frequency, or extent of pre-tubular aggregate formation. Pre-tubular aggregate formation is the cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.

def
Any process that mediates the transfer of information from one cell to another that modulates the rate, frequency, or extent of pre-tubular aggregate formation. Pre-tubular aggregate formation is the cell adhesion process in which mesenchymal cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.

GO:0072168 : specification of anterior mesonephric tubule identity
	is_a GO:0072098

GO:0072169 : specification of posterior mesonephric tubule identity
	is_a GO:0072098

GO:0072689 : MCM complex assembly
def ~~The aggregation, arrangement and bonding together of a set of components to form an MCM complex, a hexameric protein complex required for the initiation and regulation of DNA replication.~~	def The aggregation, arrangement and bonding together of a set of components to form an MCM complex, a hexameric protein complex required for the initiation and regulation of DNA replication.

GO:0080120 : CAAX-box protein maturation
relationship ~~has_part GO:0051605~~	relationship has_part GO:0016485

GO:0080184 : response to phenylpropanoid

def
Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a phenylpropanoid stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. A phenylpropoanoid is any of secondary metabolites with structures based on a phenylpropane skeleton. The class includes phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules. Phenylpropanoids are also precursors of lignin.

def
Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a phenylpropanoid stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. A phenylpropanoid is any of secondary metabolites with structures based on a phenylpropane skeleton. The class includes phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules. Phenylpropanoids are also precursors of lignin.

Other Stanza Types

Stanzas Edited

Stanza type	ID	name
Typedef	occurs_in	occurs in

File Stats

Term counts for the old and new files
Ontology	Old file	New file	Change
molecular function	9043 9043 (100.0%) defined	9062 9062 (100.0%) defined	+19
cellular component	2892 2892 (100.0%) defined	2892 2892 (100.0%) defined	0
biological process	21317 21317 (100.0%) defined	21330 21330 (100.0%) defined	+13
Obsolete	1564 (4.5% of total)	1564 (4.5% of total)	0 (0.0%)
Totals	33252 33252 (100.0%) defined 34816 inc. obsoletes	33284 33284 (100.0%) defined 34848 inc. obsoletes	+32 (+0.1%)

Ontology report info