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File 1 (03:06:2011 15:49, 1.2009) | File 2 (10:06:2011 13:58, 1.2028) |
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GO:0002154 : thyroid hormone mediated signaling pathway | |
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is_a GO:0030522 |
GO:0003700 : sequence-specific DNA binding transcription factor activity | |
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relationship part_of GO:0006355 |
GO:0003857 : 3-hydroxyacyl-CoA dehydrogenase activity | |
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synonym |
synonym "3-oxoacyl-thioester reductase activity" RELATED [PMID:19685079] "beta-hydroxybutyrylcoenzyme A dehydrogenase activity" NARROW [EC:1.1.1.35] |
GO:0004568 : chitinase activity | |
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def |
def Catalysis of the hydrolysis of 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. |
GO:0004879 : ligand-dependent nuclear receptor activity | |
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relationship part_of GO:0030522 |
GO:0004923 : leukemia inhibitory factor receptor activity | |
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relationship part_of GO:0048861 |
GO:0004952 : dopamine receptor activity | |
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relationship part_of GO:0007212 |
GO:0004963 : follicle-stimulating hormone receptor activity | |
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relationship part_of GO:0042699 |
GO:0004993 : serotonin receptor activity | |
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relationship part_of GO:0007210 |
GO:0005003 : ephrin receptor activity | |
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relationship part_of GO:0048013 |
GO:0005042 : netrin receptor activity | |
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def |
def Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. relationship part_of GO:0038007 |
GO:0005043 : netrin receptor activity involved in chemorepulsion | |
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name def is_a |
name netrin receptor activity involved in chemorepulsion def Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell away from a higher concentration of netrin. synonym "netrin receptor activity involved in negative chemotaxis" EXACT [GOC:bf] "repulsive netrin receptor activity" EXACT [GOC:bf] is_a GO:0005042 intersection_of GO:0005042 part_of GO:0050919 relationship part_of GO:0050919 |
GO:0006286 : base-excision repair, base-free sugar-phosphate removal | |
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xref |
xref Reactome:110375 "Excision of the abasic sugar phosphate (dRP) residue at the strand break" Reactome:1231000 "Excision of the abasic sugar phosphate (dRP) residue at the strand break" Reactome:1258781 "Excision of the abasic sugar phosphate (dRP) residue at the strand break" Reactome:1284239 "Excision of the abasic sugar phosphate (dRP) residue at the strand break" Reactome:1304715 "Excision of the abasic sugar phosphate (dRP) residue at the strand break" Reactome:1332351 "Excision of the abasic sugar phosphate (dRP) residue at the strand break" Reactome:1377923 "Excision of the abasic sugar phosphate (dRP) residue at the strand break" Reactome:1398294 "Excision of the abasic sugar phosphate (dRP) residue at the strand break" Reactome:1424681 "Excision of the abasic sugar phosphate (dRP) residue at the strand break" Reactome:1517174 "Excision of the abasic sugar phosphate (dRP) residue at the strand break" |
GO:0006490 : oligosaccharide-lipid intermediate biosynthetic process | |
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name def |
name oligosaccharide-lipid intermediate biosynthetic process def The chemical reactions and pathways resulting in the formation of an oligosaccharide-lipid intermediate, such as a molecule of dolichol-P-man or dolicol-P-Glc used in N-linked glycosylation. |
GO:0006509 : membrane protein ectodomain proteolysis | |
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synonym "ectodomain cleavage" EXACT [PMID:18757500] |
GO:0006921 : cellular component disassembly involved in apoptosis | |
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xref |
xref Reactome:1253537 "Apoptotic execution phase" Reactome:1280476 "Apoptotic execution phase" Reactome:1299299 "Apoptotic execution phase" Reactome:1327054 "Apoptotic execution phase" Reactome:1353148 "Apoptotic execution phase" Reactome:1373327 "Apoptotic execution phase" Reactome:1393351 "Apoptotic execution phase" Reactome:1417845 "Apoptotic execution phase" Reactome:1450936 "Apoptotic execution phase" Reactome:1471361 "Apoptotic execution phase" Reactome:1483322 "Apoptotic execution phase" Reactome:1497026 "Apoptotic execution phase" Reactome:1514413 "Apoptotic execution phase" Reactome:1521263 "Apoptotic execution phase" Reactome:1526972 "Apoptotic execution phase" Reactome:1532708 "Apoptotic execution phase" Reactome:1536122 "Apoptotic execution phase" Reactome:75153 "Apoptotic execution phase" |
GO:0007174 : epidermal growth factor catabolic process | |
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name def synonym is_a relationship |
name epidermal growth factor catabolic process def The chemical reactions and pathways resulting in the breakdown of epidermal growth factor (EGF), following internalization of the receptor-bound ligand into the signal-receiving cell. Full breakdown of epidermal growth factor results in a ligand that is unable to bind and activate its receptor. comment This term describes the breakdown of epidermal growth factor within the cell, following internalization. For proteolysis events that result in the maturation of an epidermal growth factor receptor ligand, see 'epidermal growth factor receptor ligand maturation ; GO:'. synonym "EGF breakdown" EXACT [GOC:bf] "EGF catabolism" EXACT [GOC:bf] "EGF receptor ligand processing" RELATED [GOC:bf] "epidermal growth factor breakdown" EXACT [GOC:bf] "epidermal growth factor catabolism" EXACT [GOC:bf] "epidermal growth factor ligand processing" RELATED [GOC:bf] "intracellular EGF processing" RELATED [PMID:2985587] "receptor-mediated EGF processing" RELATED [PMID:1683723] is_a GO:0042059 GO:0044257 |
GO:0007254 : JNK cascade | |
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xref |
xref Reactome:1253365 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" Reactome:1280305 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" Reactome:1299157 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" Reactome:1326883 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" Reactome:1352975 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" Reactome:1373172 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" Reactome:1393183 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" Reactome:1417675 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" Reactome:1450781 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" Reactome:1483199 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" Reactome:1526902 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" Reactome:1532635 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" Reactome:450321 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" |
GO:0007257 : activation of JUN kinase activity | |
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xref |
xref Reactome:437986 "Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation" |
GO:0008046 : axon guidance receptor activity | |
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GO:0008095 : inositol-1,4,5-trisphosphate receptor activity | |
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relationship part_of GO:0048016 |
GO:0008624 : induction of apoptosis by extracellular signals | |
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xref |
xref Reactome:1252951 "Death Receptor Signalling" Reactome:1279982 "Death Receptor Signalling" Reactome:1298875 "Death Receptor Signalling" Reactome:1326454 "Death Receptor Signalling" Reactome:1352570 "Death Receptor Signalling" Reactome:1372797 "Death Receptor Signalling" Reactome:1392807 "Death Receptor Signalling" Reactome:1417381 "Death Receptor Signalling" Reactome:1450373 "Death Receptor Signalling" Reactome:73887 "Death Receptor Signalling" |
GO:0008843 : endochitinase activity | |
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def |
def Catalysis of the hydrolysis of nonterminal 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, endochitinases cleave randomly within the chitin chain. |
GO:0018845 : 2-hydroxychromene-2-carboxylate isomerase activity | |
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def |
def Catalysis of the reaction: 2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate. (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate is also known as trans-o-hydroxybenzylidenepyruvate. |
GO:0023052 : signaling | |
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def |
def The entirety of a process in which information is transmitted. This process begins with an active signal and ends when a cellular response has been triggered. |
GO:0030518 : steroid hormone receptor signaling pathway | |
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def |
def Any series of molecular signals generated as a consequence of a steroid hormone receptor binding to one of its physiological ligands. |
GO:0035419 : activation of MAPK activity involved in innate immune response | |
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xref |
xref Reactome:433822 "NFkB and MAPK activation mediated by TRAF6" |
GO:0035626 : juvenile hormone mediated signaling pathway | |
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is_a GO:0030522 |
GO:0035638 : signal maturation | |
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def synonym relationship |
def Any process leading to the attainment of the full functional capacity of a signal. A signal is a physical entity or change in state that is used to transfer information to trigger a response, and is functional when it can activate a receptor. synonym "ligand maturation" NARROW [GOC:bf] relationship part_of GO:0023056 |
GO:0042071 : leucokinin receptor activity | |
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relationship part_of GO:0009755 |
GO:0042197 : halogenated hydrocarbon metabolic process | |
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xref |
xref Reactome:1230016 "Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide" Reactome:1257793 "Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide" Reactome:1283421 "Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide" Reactome:1303848 "Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide" Reactome:1331308 "Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide" Reactome:1356226 "Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide" Reactome:1377227 "Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide" Reactome:1397459 "Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide" Reactome:1423463 "Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide" Reactome:76475 "Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide" |
GO:0042734 : presynaptic membrane | |
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is_a |
is_a GO:0097060 |
GO:0043401 : steroid hormone mediated signaling pathway | |
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def |
def A series of molecular signals mediated by a steroid hormone binding to a receptor. |
GO:0045211 : postsynaptic membrane | |
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is_a |
is_a GO:0097060 |
GO:0047807 : cytokinin 7-beta-glucosyltransferase activity | |
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def |
def Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-7-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event. xref KEGG:R04071 RHEA:23275 |
GO:0050785 : advanced glycation end-product receptor activity | |
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def synonym |
def Combining with advanced glycation end-products to initiate a change in cell activity. Advanced glycation end-products (AGEs) form from a series of chemical reactions after an initial glycation event (a non-enzymatic reaction between reducing sugars and free amino groups of proteins). synonym "AGE receptor activity" EXACT [PMID:21590515] "RAGE activity" EXACT [PMID:21590515] |
GO:0055100 : adiponectin binding | |
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is_a GO:0005515 |
GO:0060182 : apelin receptor activity | |
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relationship part_of GO:0060183 |
GO:0060947 : cardiac vascular smooth muscle cell differentiation | |
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is_a |
is_a GO:0035886 |
GO:0060997 : dendritic spine morphogenesis | |
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is_a GO:0097061 |
GO:0071936 : coreceptor activity involved in Wnt receptor signaling pathway | |
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intersection_of GO:0015026 part_of GO:0016055 |
GO:0080062 : cytokinin 9-beta-glucosyltransferase activity | |
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def |
def Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-9-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event. xref EC:2.4.1.- KEGG:R08369 |
GO:0097004 : adipokinetic hormone binding | |
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is_a |
is_a GO:0017046 |
GO:2000143 : negative regulation of transcription initiation, DNA-dependent | |
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is_a GO:0045892 |
GO:2000144 : positive regulation of transcription initiation, DNA-dependent | |
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is_a GO:0045893 |
GO:2000686 : regulation of rubidium ion transmembrane transporter activity | |
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is_a GO:2000680 |
GO:2000696 : regulation of epithelial cell differentiation involved in kidney development | |
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is_a GO:0090183 |
GO:2000702 : regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation | |
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is_a GO:0072106 |
Ontology | Old file | New file | Change |
---|---|---|---|
molecular function |
9015 9015 (100.0%) defined |
9019 9019 (100.0%) defined |
+4 |
cellular component |
2842 2842 (100.0%) defined |
2844 2844 (100.0%) defined |
+2 |
biological process |
20800 20800 (100.0%) defined |
20831 20831 (100.0%) defined |
+31 |
Obsolete | 1559 (4.6% of total) |
1559 (4.6% of total) |
0 (0.0%) |
Totals |
32657 32657 (100.0%) defined 34216 inc. obsoletes |
32694 32694 (100.0%) defined 34253 inc. obsoletes |
+37 (+0.1%) |