# molecular_function
20140611: Has function protein kinase regulator activity (GO:0019887) in Eukaryota_PTN001268151
20140611: Has function Atg8 ligase activity (GO:0019776) in Eukaryota_PTN000333039
20140611: Has function Atg12 ligase activity (GO:0019777) in Eukaryota_PTN001029551
# cellular_component
20140611: Has function cytosol (GO:0005829) in Eukaryota_PTN001268151
20140611: Has function pre-autophagosomal structure (GO:0000407) in Eukaryota_PTN001268151
20140611: Has function extrinsic component of membrane (GO:0019898) in Eukaryota_PTN001268151
20140611: Has function Atg1p signaling complex (GO:0034273) in Eukaryota_PTN001268151
20140611: Has function pre-autophagosomal structure membrane (GO:0034045) in Eukaryota_PTN000333039
20140611: Has function Atg12-Atg5-Atg16 complex (GO:0034274) in Eukaryota_PTN000333039
20140611: Has function cytoplasm (GO:0005737) in Eukaryota_PTN000333039
20140611: Has function pre-autophagosomal structure (GO:0000407) in Eukaryota_PTN000329035
20140611: Has function intracellular (GO:0005622) in Eukaryota_PTN001029551
# biological_process
20140611: Has function protein localization to pre-autophagosomal structure (GO:0034497) in Eukaryota_PTN001268151
20140611: Has function cellular response to nitrogen starvation (GO:0006995) in Eukaryota_PTN001268151
20140611: Has function activation of protein kinase activity (GO:0032147) in Eukaryota_PTN001268151
20140611: Has function mitochondrion degradation (GO:0000422) in Eukaryota_PTN001268151
20140611: Has function nucleophagy (GO:0044804) in Eukaryota_PTN001268151
20140611: Has function macroautophagy (GO:0016236) in Eukaryota_PTN001268151
20140611: Has function cellular response to nitrogen starvation (GO:0006995) in Eukaryota_PTN000333039
20140611: Has function C-terminal protein lipidation (GO:0006501) in Eukaryota_PTN000333039
20140611: Has function nucleophagy (GO:0044804) in Eukaryota_PTN000333039
20140611: Has function autophagic vacuole assembly (GO:0000045) in Eukaryota_PTN000333039
20140611: Has function mitochondrion degradation (GO:0000422) in Eukaryota_PTN000333039
20140611: Has function macroautophagy (GO:0016236) in Eukaryota_PTN000333039
20140611: Has function autophagy (GO:0006914) in Eukaryota_PTN000333039
20140611: Has function autophagic vacuole assembly (GO:0000045) in Eukaryota_PTN000329035
20140611: Has function macroautophagy (GO:0016236) in Eukaryota_PTN000329035
20140611: Has function ascospore formation (GO:0030437) in Eukaryota_PTN000329035
20140611: Has function protein modification by small protein conjugation (GO:0032446) in Eukaryota_PTN001029551
20140611: Has function protein lipidation (GO:0006497) in Eukaryota_PTN001029551
20140611: Has function autophagy (GO:0006914) in Eukaryota_PTN001029551
# Notes
MAF 2014-06-11
reviewed with PG


Annotation inferences using phylogenetic trees

The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).