# molecular_function
20150414: Insecta_PTN000661585 has function allatostatin receptor activity (GO:0008261)
20150414: Insecta_PTN000661678 has function leucokinin receptor activity (GO:0042071)
20150414: Insecta_PTN001201583 has function neuropeptide receptor activity (GO:0008188)
20150414: Tetrapoda_PTN000661529 has function bile acid receptor activity (GO:0038181)
20150414: Eumetazoa_PTN001201576 has function G-protein coupled receptor activity (GO:0004930)
# cellular_component
20150414: Eumetazoa_PTN001201576 located in integral component of plasma membrane (GO:0005887)
# biological_process
20150414: Insecta_PTN000661585 participates in neuropeptide signaling pathway (GO:0007218)
20150414: Insecta_PTN001201583 participates in neuropeptide signaling pathway (GO:0007218)
20150414: Eumetazoa_PTN001201576 participates in G-protein coupled receptor signaling pathway (GO:0007186)
# Notes



Annotation inferences using phylogenetic trees

The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).