# molecular_function # cellular_component 20150121: Eukaryota_PTN001197414 located in proteasome regulatory particle, base subcomplex (GO:0008540) 20150121: Eukaryota_PTN001197414 located in cytoplasm (GO:0005737) 20150121: Eukaryota_PTN001197414 located in nucleus (GO:0005634) 20150121: Eukaryota_PTN001197414 located in proteasome regulatory particle (GO:0005838) # biological_process 20150121: Eukaryota_PTN001197414 participates in positive regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032436) 20150121: Eukaryota_PTN001197414 participates in proteasome regulatory particle assembly (GO:0070682) # Notes MAF: function linked to proteasome assembly and function, I would not propagate the transcription stuff. Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).