# molecular_function 20150313: Theria _PTN000627437 has function fructose transmembrane transporter activity (GO:0005353) 20150313: LUCA_PTN000627328 has function sugar:proton symporter activity (GO:0005351) 20150313: root_PTN000756124 has function glucose transmembrane transporter activity (GO:0005355) # cellular_component 20150313: root_PTN000627327 located in integral component of plasma membrane (GO:0005887) # biological_process 20150313: Theria _PTN000627437 participates in fructose transport (GO:0015755) 20150313: root_PTN000756124 participates in glucose import (GO:0046323) 20150313: Euteleostomi_PTN000627513 participates in cellular response to insulin stimulus (GO:0032869) 20150313: root_PTN000756124 participates in hexose transmembrane transport (GO:0035428) 20150313: root_PTN000756124 participates in glucose transport (GO:0015758) # Notes 13-March-2015, HM Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).