# molecular_function
20150409: Dikarya_PTN001161372 has function siderophore transmembrane transporter activity (GO:0015343)
20150409: Nakaseomyces/Candida clade_PTN001160475 has function drug transmembrane transporter activity (GO:0015238)
20150409: root_PTN001519109 has function sugar:proton symporter activity (GO:0005351)
20150409: Bacteria <prokaryote>_PTN000606697 has function nitrite efflux transmembrane transporter activity (GO:0015514)
20150409: Bacteria <prokaryote>_PTN000606697 has function nitrate transmembrane transporter activity (GO:0015112)
20150409: Dikarya_PTN001161079 has function basic amino acid transmembrane transporter activity (GO:0015174)
20150409: Dikarya_PTN001161029 has function ammonium transmembrane transporter activity (GO:0008519)
20150409: root_PTN001518796 has function substrate-specific transmembrane transporter activity (GO:0022891)
20150409: Embryophyta_PTN001160805 has function nitrate transmembrane transporter activity (GO:0015112)
# cellular_component
20150409: cellular organisms_PTN000605533 located in lysosomal membrane (GO:0005765)
20150409: Dikarya_PTN001161372 located in vacuolar membrane (GO:0005774)
20150409: Dikarya_PTN001161372 located in endosome (GO:0005768)
20150409: Dikarya_PTN001161372 located in intracellular membrane-bounded organelle (GO:0043231)
20150409: Dikarya_PTN001161372 located in cytoplasm (GO:0005737)
20150409: Dikarya_PTN001161372 located in plasma membrane (GO:0005886)
20150409: Nakaseomyces/Candida clade_PTN001160475 located in plasma membrane (GO:0005886)
20150409: Bacteria <prokaryote>_PTN000606697 located in integral component of plasma membrane (GO:0005887)
20150409: Dikarya_PTN001161079 located in fungal-type vacuole membrane (GO:0000329)
20150409: Dikarya_PTN001161029 located in plasma membrane (GO:0005886)
20150409: Bacteria <prokaryote>_PTN000606006 located in integral component of plasma membrane (GO:0005887)
20150409: Embryophyta_PTN001160805 located in plant-type vacuole membrane (GO:0009705)
20150409: Embryophyta_PTN001160805 located in plasma membrane (GO:0005886)
20150409: root_PTN001518796 located in integral component of membrane (GO:0016021)
# biological_process
20150409: Dikarya_PTN001161372 participates in cellular iron ion homeostasis (GO:0006879)
20150409: Dikarya_PTN001161372 participates in siderophore transmembrane transport (GO:0044718)
20150409: Bacteria <prokaryote>_PTN001160783 participates in drug transmembrane transport (GO:0006855)
20150409: Nakaseomyces/Candida clade_PTN001160475 participates in drug transmembrane transport (GO:0006855)
20150409: root_PTN001519109 participates in carbohydrate transport (GO:0008643)
20150409: Bacteria <prokaryote>_PTN000606697 participates in nitrite transport (GO:0015707)
20150409: Bacteria <prokaryote>_PTN000606697 participates in nitrate transport (GO:0015706)
20150409: Dikarya_PTN001161079 participates in basic amino acid transport (GO:0015802)
20150409: Dikarya_PTN001161029 participates in ammonium transport (GO:0015696)
20150409: Embryophyta_PTN001160805 participates in cellular response to nitrate (GO:0071249)
20150409: Embryophyta_PTN001160805 participates in nitrate transport (GO:0015706)
20150409: root_PTN001518796 participates in transmembrane transport (GO:0055085)
# Notes
MAF: Many duplications, very specific substrates and very few experimental annotations lead to very few propagations.


Annotation inferences using phylogenetic trees

The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).