# molecular_function
20150209: Eukaryota_PTN000571155 has function microtubule binding (GO:0008017)
20150209: Eukaryota_PTN000571155 has function Rho GTPase activator activity (GO:0005100)
20150209: Eukaryota_PTN000571155 has function GTPase activator activity (GO:0005096)
# cellular_component
20150209: Eukaryota_PTN000571155 located in centralspindlin complex (GO:0097149)
# biological_process
20150209: Eukaryota_PTN000571155 participates in actomyosin contractile ring assembly (GO:0000915)
20150209: Eukaryota_PTN000571155 participates in mitotic spindle assembly (GO:0090307)
20150209: Eukaryota_PTN000571155 participates in positive regulation of Rho GTPase activity (GO:0032321)
# Notes



Annotation inferences using phylogenetic trees

The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).