# molecular_function 20140919: Eukaryota_PTN000325444 has function UFM1 hydrolase activity (GO:0071567) 20140919: root_PTN000325443 has function small conjugating protein-specific protease activity (GO:0019783) 20140919: root_PTN000325443 has function thiolester hydrolase activity (GO:0016790) # cellular_component # biological_process 20140919: root_PTN000325443 participates in proteolysis (GO:0006508) # Notes Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).