# molecular_function
20140922: Eukaryota_PTN000860681 has function cytoskeletal protein binding (GO:0008092)
20140922: Eukaryota_PTN000860681 has function phospholipid binding (GO:0005543)
# cellular_component
20140924: Euteleostomi_PTN000102991 located in neuron projection (GO:0043005)
20140924: Opisthokonta_PTN000860688 located in endosome (GO:0005768)
20140924: Eukaryota_PTN000860681 located in membrane (GO:0016020)
20140924: Eukaryota_PTN000860681 located in endomembrane system (GO:0012505)
20140922: Eukaryota_PTN000860681 located in membrane-bounded vesicle (GO:0031988)
# biological_process
20140924: Eukaryota_PTN000860681 participates in cytoskeleton organization (GO:0007010)
20140924: Euteleostomi_PTN000102991 participates in neuron projection morphogenesis (GO:0048812)
20140924: Opisthokonta_PTN000860688 participates in regulation of endocytosis (GO:0030100)
20140924: Eukaryota_PTN000860681 participates in membrane tubulation (GO:0097320)
20140924: Eukaryota_PTN000860681 participates in regulation of vesicle-mediated transport (GO:0060627)
20140924: Deuterostomia_PTN000102963 lost/modified cytokinesis (GO:0000910) capacity
20140922: Eukaryota_PTN000860681 participates in cytokinesis (GO:0000910)
# Notes
Annotated by VH and reviewed by PG. 


Annotation inferences using phylogenetic trees

The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).