# HISTORY 28 Sep 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20160928: Eukaryota_PTN000917495 contributes to function RNA polymerase II core promoter proximal region sequence-specific DNA binding (GO:0000978) 20160928: root_PTN000194668 has function asparaginase activity (GO:0004067) 20160928: Eukaryota_PTN000917495 has LOST/MODIFIED function asparaginase activity (GO:0004067) 20160928: Eukaryota_PTN000917495 has function transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding (GO:0001077) # cellular_component 20160928: Eukaryota_PTN000917495 is found in nuclear chromatin (GO:0000790) 20160928: Eukaryota_PTN000917495 is found in MBF transcription complex (GO:0030907) 20160928: Bacteria _PTN000194687 is found in cytosol (GO:0005829) 20160928: root_PTN000194668 is found in cytoplasm (GO:0005737) # biological_process 20160928: Eukaryota_PTN000917495 participates in regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) 20160928: Eukaryota_PTN000917495 participates in positive regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0071931) 20160928: root_PTN000194668 participates in asparagine catabolic process (GO:0006530) 20160928: Eukaryota_PTN000917495 does NOT participate in asparagine catabolic process (GO:0006530) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).