# HISTORY 12 Oct 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20161012: root_PTN002464028 has function ATP-dependent peptidase activity (GO:0004176) 20161012: Eukaryota_PTN000005479 has function mitochondrial light strand promoter anti-sense binding (GO:0070361) # cellular_component 20161012: Eukaryota_PTN000005479 is found in mitochondrial matrix (GO:0005759) # biological_process 20161012: root_PTN002464028 participates in proteolysis (GO:0006508) 20161012: Eukaryota_PTN000005479 participates in mitochondrion organization (GO:0007005) 20161012: root_PTN002464028 participates in proteolysis involved in cellular protein catabolic process (GO:0051603) 20161012: root_PTN002464028 participates in misfolded or incompletely synthesized protein catabolic process (GO:0006515) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).