# HISTORY 26 Apr 2016: Updated by: TOUCHUP-v1.15 19 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20151130: Dikarya_PTN002172173 has function GTPase activator activity (GO:0005096) # cellular_component 20151130: Dikarya_PTN002172173 is found in mitotic spindle pole body (GO:0044732) 20151130: Dikarya_PTN002172173 is found in Bfa1-Bub2 complex (GO:1990334) # biological_process 20151130: Dikarya_PTN002172173 participates in regulation of Ras protein signal transduction (GO:0046578) 20151130: Dikarya_PTN002172173 participates in mitotic spindle orientation checkpoint (GO:0031578) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).