# HISTORY 26 Apr 2016: Updated by: TOUCHUP-v1.15 19 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20151007: Eukaryota_PTN001282244 has function S-adenosylmethionine-dependent methyltransferase activity (GO:0008757) 20151007: Fungi_PTN001285370 has function protein-arginine N5-methyltransferase activity (GO:0019702) 20151007: Opisthokonta_PTN001285367 has function guanidinoacetate N-methyltransferase activity (GO:0030731) # cellular_component 20151007: Eukaryota_PTN001282244 is found in nucleus (GO:0005634) 20151007: Eukaryota_PTN001282244 is found in cytoplasm (GO:0005737) # biological_process 20151007: Eukaryota_PTN001282244 participates in S-adenosylhomocysteine metabolic process (GO:0046498) 20151007: Eukaryota_PTN001282244 participates in S-adenosylmethionine metabolic process (GO:0046500) 20151007: Fungi_PTN001285370 participates in peptidyl-arginine methylation (GO:0018216) 20151007: Opisthokonta_PTN001285367 participates in creatine biosynthetic process (GO:0006601) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).