# HISTORY 16 Aug 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20160816: Euteleostomi_PTN001595864 has function GTPase activity (GO:0003924) # cellular_component 20160816: Theria _PTN000365263 is found in endoplasmic reticulum membrane (GO:0005789) # biological_process 20160816: Theria _PTN000365263 participates in cellular response to interferon-beta (GO:0035458) 20160816: Theria _PTN000365263 participates in defense response (GO:0006952) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).