# HISTORY 07 oct. 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20161007: Eukaryota_PTN001592797 has function unfolded protein binding (GO:0051082) # cellular_component 20161007: Fungi_PTN001278552 is found in Vma12-Vma22 assembly complex (GO:1990871) 20161007: Eukaryota_PTN001592797 is found in extrinsic component of endoplasmic reticulum membrane (GO:0042406) # biological_process # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).