# HISTORY 26 Apr 2016: Updated by: TOUCHUP-v1.15 19 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150818: root_PTN001275041 has function iron ion transmembrane transporter activity (GO:0005381) 20150818: root_PTN001275041 has function manganese ion transmembrane transporter activity (GO:0005384) # cellular_component 20150818: root_PTN001275041 is found in membrane (GO:0016020) 20150818: Eukaryota_PTN000783402 is found in vacuolar membrane (GO:0005774) 20150818: Fungi_PTN001275044 is found in fungal-type vacuole membrane (GO:0000329) 20150818: Magnoliophyta_PTN002069165 is found in ER body (GO:0010168) 20150818: Magnoliophyta_PTN002069165 is found in endoplasmic reticulum (GO:0005783) # biological_process 20150818: root_PTN001275041 participates in cellular manganese ion homeostasis (GO:0030026) 20150818: root_PTN001275041 participates in intracellular sequestering of iron ion (GO:0006880) 20150818: root_PTN001275041 participates in manganese ion transmembrane transport (GO:0071421) 20150818: root_PTN001275041 participates in cellular response to iron ion (GO:0071281) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).