# HISTORY 21 Feb 2017: Saved by donghuili using Paint 2.0-beta14 # molecular_function 20170221: Eukaryota_PTN001272081 has function polyubiquitin binding (GO:0031593) # cellular_component 20170221: Eukaryota_PTN001272081 is found in nucleus (GO:0005634) 20170221: Euteleostomi_PTN000786812 is found in cytoplasm (GO:0005737) # biological_process 20170221: Euteleostomi_PTN000786812 participates in response to ischemia (GO:0002931) 20170221: Euteleostomi_PTN000786812 participates in protein K63-linked deubiquitination (GO:0070536) 20170221: Euteleostomi_PTN000786819 participates in double-strand break repair (GO:0006302) 20170221: Euteleostomi_PTN000786819 participates in G2 DNA damage checkpoint (GO:0031572) 20170221: Euteleostomi_PTN000786819 participates in positive regulation of DNA repair (GO:0045739) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).