# HISTORY 26 Apr 2016: Updated by: TOUCHUP-v1.15 19 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150909: root_PTN001254638 has function substrate-specific transmembrane transporter activity (GO:0022891) 20150909: Bacteria _PTN000778000 has function drug transporter activity (GO:0090484) 20150909: Gammaproteobacteria_PTN001254681 has function spermidine transmembrane transporter activity (GO:0015606) 20150909: Gammaproteobacteria_PTN001254652 has function spermidine transmembrane transporter activity (GO:0015606) 20150909: Proteobacteria_PTN001254648 has function antiporter activity (GO:0015297) 20150909: Proteobacteria_PTN001254648 has function amino-acid betaine transmembrane transporter activity (GO:0015199) 20150909: Proteobacteria_PTN001254648 has function choline transmembrane transporter activity (GO:0015220) # cellular_component 20150909: root_PTN001254638 is found in integral component of plasma membrane (GO:0005887) # biological_process 20150909: root_PTN001254638 participates in transmembrane transport (GO:0055085) 20150909: Bacteria _PTN000778000 participates in drug export (GO:0046618) 20150909: Gammaproteobacteria_PTN001254681 participates in spermidine transmembrane transport (GO:1903711) 20150909: Gammaproteobacteria_PTN001254652 participates in spermidine transmembrane transport (GO:1903711) 20150909: Proteobacteria_PTN001254648 participates in glycine betaine transport (GO:0031460) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).