# HISTORY 22 Nov 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20161122: root_PTN000775525 has function glucokinase activity (GO:0004340) 20161122: Bacteria _PTN000775527 has function transcription factor activity, sequence-specific DNA binding (GO:0003700) 20161122: Bacteria _PTN000775527 has LOST/MODIFIED function glucokinase activity (GO:0004340) # cellular_component 20161122: node_PTN000775536 is found in cytosol (GO:0005829) # biological_process 20161122: Bacteria _PTN000775527 participates in regulation of transcription, DNA-templated (GO:0006355) 20161122: root_PTN000775525 participates in glycolytic process (GO:0006096) 20161122: Bacteria _PTN000775527 does NOT participate in glycolytic process (GO:0006096) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).