# HISTORY 26 Apr 2016: Updated by: TOUCHUP-v1.15 18 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150722: root_PTN001247839 has function oxidoreductase activity (GO:0016491) 20150722: Bacteria _PTN001247840 has function formate dehydrogenase (quinone) activity (GO:0036397) 20150722: Proteobacteria_PTN000763942 has function hydrogenase (acceptor) activity (GO:0033748) # cellular_component 20150722: root_PTN001247839 is found in integral component of membrane (GO:0016021) 20150722: root_PTN001247839 is found in plasma membrane (GO:0005886) 20150722: Bacteria _PTN001247840 is found in formate dehydrogenase complex (GO:0009326) 20150722: Proteobacteria_PTN000763942 is found in [Ni-Fe] hydrogenase complex (GO:0044569) # biological_process 20150722: root_PTN001247839 participates in anaerobic respiration (GO:0009061) 20150722: Bacteria _PTN001247840 participates in formate oxidation (GO:0015944) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).