# HISTORY 21 Oct 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20161021: Gammaproteobacteria_PTN000769367 has function DNA replication origin binding (GO:0003688) 20161021: Bacteria _PTN000769352 has function DNA replication origin binding (GO:0003688) 20161021: Gammaproteobacteria_PTN001247363 has LOST/MODIFIED function DNA replication origin binding (GO:0003688) # cellular_component 20161021: Bacteria _PTN000769352 is found in plasma membrane (GO:0005886) 20161021: Gammaproteobacteria_PTN001247363 is NOT found in plasma membrane (GO:0005886) 20161021: Branchiostegus japonicus_Q89BD6 is NOT found in cytosol (GO:0005829) 20161021: Branchiostegus japonicus_Q89BF5 is NOT found in cytosol (GO:0005829) 20161021: Branchiostegus japonicus_Q89BD6 is NOT found in cytoplasm (GO:0005737) 20161021: Branchiostegus japonicus_Q89BF5 is NOT found in cytoplasm (GO:0005737) 20161021: root_PTN001574578 is found in cytoplasm (GO:0005737) # biological_process 20161021: root_PTN001574578 participates in DNA replication (GO:0006260) 20161021: Bacteria _PTN000769352 participates in DNA replication initiation (GO:0006270) 20161021: Bacteria _PTN001247366 participates in DNA strand elongation involved in DNA replication (GO:0006271) 20161021: Gammaproteobacteria_PTN001247363 participates in negative regulation of DNA-dependent DNA replication initiation (GO:0032297) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).