# HISTORY 24 May 2016: Saved by pascalegaudet using Paint 2.0-beta19 # molecular_function 20160523: Eukaryota_PTN002009488 has function phosphatidylinositol binding (GO:0035091) # cellular_component 20160523: Eukaryota_PTN002009488 is found in membrane (GO:0016020) # biological_process 20160523: Deuterostomia_PTN002009495 participates in determination of ventral identity (GO:0048264) 20160524: Eukaryota_PTN002009488 participates in intracellular signal transduction (GO:0035556) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).