# HISTORY 21 Feb 2017: Saved by donghuili using Paint 2.0-beta14 # molecular_function # cellular_component 20170221: Eukaryota_PTN002008627 is found in nucleus (GO:0005634) 20170221: Eukaryota_PTN002008627 is found in cytoplasm (GO:0005737) # biological_process 20170221: Eukaryota_PTN002008627 participates in DNA replication (GO:0006260) 20170221: Eukaryota_PTN002008627 participates in chromosome organization (GO:0051276) 20170221: Eukaryota_PTN002008627 participates in DNA replication checkpoint (GO:0000076) 20170221: Bilateria_PTN002008632 participates in mitotic cell cycle (GO:0000278) 20170221: Bilateria_PTN002008632 participates in regulation of DNA-dependent DNA replication initiation (GO:0030174) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).