# HISTORY 04 Aug 2016: Updated by: TOUCHUP-v1.21 # molecular_function # cellular_component 20160422: Deuterostomia_PTN002006936 is found in extracellular region (GO:0005576) # biological_process 20160422: Euteleostomi_PTN002006938 participates in commissural neuron differentiation in spinal cord (GO:0021528) 20160422: Euteleostomi_PTN002006938 participates in dorsal spinal cord development (GO:0021516) 20160422: Euteleostomi_PTN002006938 participates in axon guidance (GO:0007411) 20160422: Euteleostomi_PTN002006938 participates in negative regulation of canonical Wnt signaling pathway (GO:0090090) 20160422: Euteleostomi_PTN002006938 participates in forebrain development (GO:0030900) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).