# HISTORY 28 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.12 18 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150917: Ascomycota_PTN002000565 contributes to function histone deacetylase activity (GO:0004407) # cellular_component 20150917: Ascomycota_PTN002000565 is found in Rpd3L complex (GO:0033698) 20150917: Ascomycota_PTN002000565 is found in cytosol (GO:0005829) 20150917: Ascomycota_PTN002000565 is found in Clr6 histone deacetylase complex I'' (GO:1990483) # biological_process 20150917: Ascomycota_PTN002000565 participates in negative regulation of chromatin silencing at rDNA (GO:0061188) 20150917: Ascomycota_PTN002000565 participates in transfer RNA gene-mediated silencing (GO:0061587) 20150917: Ascomycota_PTN002000565 participates in negative regulation of chromatin silencing at telomere (GO:0031939) 20150917: Ascomycota_PTN002000565 participates in negative regulation of chromatin silencing at silent mating-type cassette (GO:0061186) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).