# HISTORY 28 Mar 2016: Updated by: TOUCHUP-v1.15 14 Mar 2016: Updated by: TOUCHUP-v1.12 18 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function # cellular_component 20151118: Ascomycota_PTN001997200 is found in integral component of nuclear outer membrane (GO:0031309) 20151118: Ascomycota_PTN001997200 is found in nuclear pore transmembrane ring (GO:0070762) # biological_process 20151118: Ascomycota_PTN001997200 participates in protein import into nucleus (GO:0006606) 20151118: Ascomycota_PTN001997200 participates in spindle pole body duplication (GO:0030474) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES This family comprises the POM34, a POM, which is an integral membrane protein of the nuclear envelope membrane domain of the nuclear pore complex. POM34 is present in S. cerevisiae and other yeast, but not in humans [Hoelz et al. 2011 (PMID:21495847), Aitchison and Rout 2012 (PMID:22419078), and Kabachinski and Schwartz 2015 (PMID:26046137)]. # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).