# HISTORY 06 Aug 2016: Saved by suzi using Paint 2.22 # molecular_function 20160307: root_PTN000698504 has function ubiquitin protein ligase binding (GO:0031625) # cellular_component 20160307: root_PTN000698504 is found in cytoplasm (GO:0005737) 20160307: root_PTN000698504 is found in SCF ubiquitin ligase complex (GO:0019005) 20160307: Eumetazoa_PTN001229949 is found in cytosol (GO:0005829) 20160307: Eumetazoa_PTN001974273 is found in cytoplasmic mRNA processing body (GO:0000932) 20160307: Magnoliophyta_PTN001561970 is found in cytosol (GO:0005829) 20160307: Magnoliophyta_PTN000698663 is found in nucleus (GO:0005634) 20160307: Bilateria_PTN000698511 is found in nucleus (GO:0005634) 20160307: Embryophyta_PTN001229862 is found in nucleus (GO:0005634) # biological_process 20160307: root_PTN000698504 participates in proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161) 20160307: root_PTN000698504 participates in regulation of proteolysis (GO:0030162) 20160307: root_PTN000698504 participates in protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787) 20160307: Eumetazoa_PTN001229949 participates in neurogenesis (GO:0022008) 20160307: Euteleostomi_PTN000698349 participates in cerebral cortex development (GO:0021987) 20160307: Euteleostomi_PTN000698349 participates in dendrite morphogenesis (GO:0048813) 20160307: Magnoliophyta_PTN001561970 participates in negative regulation of cytokinin-activated signaling pathway (GO:0080037) 20160307: Magnoliophyta_PTN001561970 participates in regulation of phenylpropanoid metabolic process (GO:2000762) 20160307: Bilateria_PTN000698411 participates in circadian behavior (GO:0048512) 20160307: Bilateria_PTN000698411 participates in modulation of synaptic transmission (GO:0050804) 20160307: Bilateria_PTN000698411 participates in adult locomotory behavior (GO:0008344) 20160307: Euteleostomi_PTN000698171 participates in SMAD protein signal transduction (GO:0060395) 20160307: Embryophyta_PTN001229862 participates in induced systemic resistance, jasmonic acid mediated signaling pathway (GO:0009864) 20160307: Pentapetalae_PTN001974705 participates in defense response to bacterium (GO:0042742) 20160307: Pentapetalae_PTN001974705 participates in regulation of jasmonic acid mediated signaling pathway (GO:2000022) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED ## Annotations that have been removed. 20160307: Magnoliophyta_PTN001561740 to nucleus (GO:0005634) using [TAIR:locus:2056705, TAIR:locus:2202765, TAIR:locus:2175143, TAIR:locus:2012547, TAIR:locus:2168738] - lacks supporting evidence 20160307: Magnoliophyta_PTN001974366 to nucleus (GO:0005634) using [TAIR:locus:2019215] - lacks supporting evidence 20160307: Eukaryota_PTN001974461 to response to stress (GO:0006950) is an excluded term and not to be used for annotation 20160307: Bilateria_PTN001229991 to nucleus (GO:0005634) using [UniProtKB:Q8N961] - lacks supporting evidence # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).