# HISTORY
27 Mar 2016: Updated by: TOUCHUP-v1.15
18 Mar 2016: Updated by: TOUCHUP-v1.14

# molecular_function
20150213: root_PTN000681419 has function calmodulin-dependent protein kinase activity (GO:0004683) 
20150213: root_PTN000681419 has function calcium-dependent protein serine/threonine kinase activity (GO:0009931) 
20150213: root_PTN000681419 has function calmodulin binding (GO:0005516) 
20150213: Eukaryota_PTN001553005 has function signal transducer activity (GO:0004871) 
20150213: Euteleostomi_PTN000721059 has function microtubule binding (GO:0008017) 

# cellular_component
20150213: root_PTN000681419 is found in cytoplasm (GO:0005737) 
20150213: root_PTN000681419 is found in nucleus (GO:0005634) 
20150213: Viridiplantae_PTN000681739 is found in plasma membrane (GO:0005886) 

# biological_process
20150213: root_PTN000681419 participates in protein autophosphorylation (GO:0046777) 
20150213: root_PTN000681419 participates in peptidyl-serine phosphorylation (GO:0018105) 
20150213: root_PTN000681419 participates in intracellular signal transduction (GO:0035556) 
20150213: Chordata_PTN001553006 participates in Ras protein signal transduction (GO:0007265) 
20150213: node_PTN000681750 participates in abscisic acid-activated signaling pathway (GO:0009738) 
20150213: Eukaryota_PTN001553005 participates in cell surface receptor signaling pathway (GO:0007166) 
20150213: Eukaryota_PTN001553005 participates in MAPK cascade (GO:0000165) 
20150213: Euteleostomi_PTN000681525 participates in cellular response to vascular endothelial growth factor stimulus (GO:0035924) 
20150213: Euteleostomi_PTN000681525 participates in inflammatory response (GO:0006954) 
20150213: Euteleostomi_PTN000681525 participates in vascular endothelial growth factor receptor signaling pathway (GO:0048010) 
20150213: Euteleostomi_PTN000721059 participates in neuron migration (GO:0001764) 
20150213: Chordata_PTN000680635 participates in positive regulation of transcription, DNA-templated (GO:0045893) 

# WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED
## Annotations that have been removed.
20150213: Opisthokonta_PTN000757376 to cellular response to stress (GO:0033554) is an excluded term and not to be used for annotation

# NOTES

# REFERENCE
Annotation inferences using phylogenetic trees
The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).