# HISTORY 27 Mar 2016: Updated by: TOUCHUP-v1.15 18 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150812: Eukaryota_PTN001216652 has function transcription factor activity, sequence-specific DNA binding (GO:0003700) 20150812: Eukaryota_PTN001216652 has function RNA polymerase II regulatory region sequence-specific DNA binding (GO:0000977) # cellular_component 20150812: Eukaryota_PTN001216652 is found in nucleus (GO:0005634) # biological_process 20150812: Eukaryota_PTN001216652 participates in regulation of transcription from RNA polymerase II promoter (GO:0006357) 20150812: Eukaryota_PTN001216652 participates in anterior/posterior axis specification (GO:0009948) 20150812: Eukaryota_PTN001216652 participates in organ morphogenesis (GO:0009887) 20150812: Eukaryota_PTN001216652 participates in cell differentiation (GO:0030154) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED ## Annotations that have been removed. 20150812: Eukaryota_PTN001216652 to embryo development (GO:0009790) is an excluded term and not to be used for annotation # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).