# HISTORY 27 Mar 2016: Updated by: TOUCHUP-v1.15 18 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150818: root_PTN001957406 has function oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen (GO:0016709) 20150818: root_PTN001957406 has function heme binding (GO:0020037) 20150818: Euteleostomi_PTN000669179 has function steroid 11-beta-monooxygenase activity (GO:0004507) 20150818: Euteleostomi_PTN000669179 has function corticosterone 18-monooxygenase activity (GO:0047783) 20150818: Euteleostomi_PTN000669219 has function cholesterol monooxygenase (side-chain-cleaving) activity (GO:0008386) # cellular_component 20150818: root_PTN001957406 is found in intracellular membrane-bounded organelle (GO:0043231) 20150818: Chordata_PTN000669177 is found in mitochondrial inner membrane (GO:0005743) 20150818: Embryophyta_PTN001547377 is found in chloroplast outer membrane (GO:0009707) 20150818: Embryophyta_PTN001547377 is found in endoplasmic reticulum (GO:0005783) # biological_process 20150818: root_PTN001957406 participates in secondary metabolite biosynthetic process (GO:0044550) 20150818: root_PTN001957406 participates in small molecule metabolic process (GO:0044281) 20150818: node_PTN001209008 participates in dehydroaustinol biosynthetic process (GO:1900563) 20150818: node_PTN001209008 participates in austinol biosynthetic process (GO:1900560) 20150818: Chordata_PTN000669177 participates in C21-steroid hormone biosynthetic process (GO:0006700) 20150818: Chordata_PTN000669177 participates in cellular response to peptide hormone stimulus (GO:0071375) 20150818: Chordata_PTN000669177 participates in glucocorticoid biosynthetic process (GO:0006704) 20150818: Chordata_PTN000669177 participates in cholesterol metabolic process (GO:0008203) 20150818: Chordata_PTN000669177 participates in cortisol metabolic process (GO:0034650) 20150818: Euteleostomi_PTN000669179 participates in aldosterone biosynthetic process (GO:0032342) 20150818: Embryophyta_PTN001547377 participates in ent-kaurene oxidation to kaurenoic acid (GO:0010241) 20150818: Embryophyta_PTN001547377 participates in gibberellic acid mediated signaling pathway (GO:0009740) 20150818: Embryophyta_PTN001547377 participates in gibberellin biosynthetic process (GO:0009686) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).