# HISTORY 22 Nov 2016: Saved by mfeuerma using Paint 2.22 # molecular_function 20161122: root_PTN002385416 has function serine-type endopeptidase activity (GO:0004252) # cellular_component 20161122: root_PTN002385416 is found in extracellular space (GO:0005615) 20161122: Chordata_PTN002385417 is found in integral component of plasma membrane (GO:0005887) 20161122: Chordata_PTN002385417 is NOT found in extracellular space (GO:0005615) # biological_process 20161122: node_PTN002385419 participates in complement activation, lectin pathway (GO:0001867) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).