# HISTORY 27 Mar 2016: Updated by: TOUCHUP-v1.15 18 Nov 2015: redistribution of PTN000660132 from PTHR24229 to PTHR24242 18 Mar 2016: Updated by: TOUCHUP-v1.14 # molecular_function 20150602: Opisthokonta_PTN001544342 has function G-protein coupled receptor activity (GO:0004930) 20150602: node_PTN000662758 has function tachykinin receptor activity (GO:0004995) 20150820: Euteleostomi_PTN000662764 has function substance P receptor activity (GO:0016496) 20150820: Euteleostomi_PTN000662791 has function substance K receptor activity (GO:0016497) 20150820: Tetrapoda_PTN000663028 has function melatonin receptor activity (GO:0008502) 20150820: Euteleostomi_PTN001955502 has function melatonin receptor activity (GO:0008502) 20150820: Euteleostomi_PTN000663245 has function neuropeptide receptor activity (GO:0008188) 20150820: Euteleostomi_PTN000663245 has function melanin-concentrating hormone receptor activity (GO:0030273) 20150602: node_PTN001955576 has function pancreatic polypeptide receptor activity (GO:0001602) # cellular_component 20150602: Opisthokonta_PTN001544342 is found in integral component of plasma membrane (GO:0005887) # biological_process 20150820: Opisthokonta_PTN001544342 participates in cell surface receptor signaling pathway (GO:0007166) 20150602: Opisthokonta_PTN001544342 participates in G-protein coupled receptor signaling pathway (GO:0007186) 20150820: node_PTN000662758 participates in neuropeptide signaling pathway (GO:0007218) 20150820: node_PTN000662758 participates in synaptic transmission (GO:0007268) 20150820: node_PTN000662758 participates in positive regulation of smooth muscle contraction (GO:0045987) 20150820: Amniota_PTN000663094 participates in feeding behavior (GO:0007631) 20150820: Amniota_PTN000663094 participates in neuropeptide signaling pathway (GO:0007218) 20150820: Euteleostomi_PTN000663009 participates in circadian rhythm (GO:0007623) 20150820: Euteleostomi_PTN001955502 participates in circadian rhythm (GO:0007623) 20150820: node_PTN001955526 participates in neuropeptide signaling pathway (GO:0007218) 20150820: node_PTN001955526 participates in synaptic transmission (GO:0007268) 20150820: node_PTN001955526 participates in feeding behavior (GO:0007631) 20140924: Diptera_PTN000660132 participates in germ cell migration (GO:0008354) 20140924: Diptera_PTN000660132 participates in germ cell development (GO:0007281) 20150602: node_PTN001955576 participates in neuropeptide signaling pathway (GO:0007218) 20150820: node_PTN001955576 participates in feeding behavior (GO:0007631) 20150820: node_PTN001955576 participates in blood circulation (GO:0008015) 20150820: Euteleostomi_PTN000662876 participates in circadian rhythm (GO:0007623) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES Annotated by PG and VH # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).