# HISTORY 09 Jul 2016: Updated by: TOUCHUP-v1.19 30 Jun 2016: Updated by: TOUCHUP-v1.19 # molecular_function 20160502: Bilateria_PTN001198415 has function actin binding (GO:0003779) # cellular_component 20160502: Bilateria_PTN001198415 is found in Z disc (GO:0030018) 20160502: Bilateria_PTN001198415 is found in nucleus (GO:0005634) 20160502: Bilateria_PTN001198415 is found in actin cytoskeleton (GO:0015629) # biological_process 20160502: Bilateria_PTN001198415 participates in positive regulation of actin filament bundle assembly (GO:0032233) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).