# HISTORY 07 May 2016: Updated by: TOUCHUP-v1.18 18 Mar 2016: Updated by: TOUCHUP-v1.14 27 Mar 2016: Updated by: TOUCHUP-v1.15 # molecular_function 20150313: Bilateria_PTN001170450 has function extracellular matrix structural constituent (GO:0005201) # cellular_component 20150313: Bilateria_PTN001170450 is found in extracellular matrix (GO:0031012) # biological_process 20150313: Bilateria_PTN001170450 participates in anatomical structure morphogenesis (GO:0009653) 20150313: Bilateria_PTN001170450 participates in regulation of cellular response to growth factor stimulus (GO:0090287) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES Annotated Bilateria_PTN001170450 since the sequence is not very well conserved in more ancient members of the family. PG 2015-03-13 # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).