# HISTORY 17 Nov 2016: Saved by mfeuerma using Paint 2.22 # molecular_function # cellular_component 20161117: Opisthokonta_PTN001932250 is found in integral component of plasma membrane (GO:0005887) # biological_process 20161117: Amniota_PTN000617834 participates in synapse assembly (GO:0007416) 20161117: Amniota_PTN000617834 participates in chemical synaptic transmission (GO:0007268) 20161117: Monosiga brevicollis_A9UU29 does NOT participate in nervous system development (GO:0007399) 20161117: Opisthokonta_PTN001932250 participates in nervous system development (GO:0007399) 20161117: Opisthokonta_PTN001932250 participates in cell adhesion (GO:0007155) 20161117: Opisthokonta_PTN001932250 participates in cell-cell signaling (GO:0007267) 20161117: Euteleostomi_PTN000617322 participates in synapse assembly (GO:0007416) # WARNINGS - THE FOLLOWING HAVE BEEN REMOVED FOR THE REASONS NOTED # NOTES # REFERENCE Annotation inferences using phylogenetic trees The goal of the GO Reference Genome Project, described in PMID 19578431, is to provide accurate, complete and consistent GO annotations for all genes in twelve model organism genomes. To this end, GO curators are annotating evolutionary trees from the PANTHER database with GO terms describing molecular function, biological process and cellular component. GO terms based on experimental data from the scientific literature are used to annotate ancestral genes in the phylogenetic tree by sequence similarity (ISS), and unannotated descendants of these ancestral genes are inferred to have inherited these same GO annotations by descent. The annotations are done using a tool called PAINT (Phylogenetic Annotation and INference Tool).